ISMARA results: UAAUGCU

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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for UAAUGCU

Z-value: 0.00

Motif logo

miRNA associated with seed UAAUGCU

Name	miRBASE accession
hsa-miR-155-5p miRBase	MIMAT0000646

Activity profile of UAAUGCU motif

Sorted Z-values of UAAUGCU motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr20_+_48807351 Show fit	5.18	ENST00000303004.3	CEBPB Ensembl NCBI GeneCards UniProt NextProt Show fit	CCAAT/enhancer binding protein (C/EBP), beta
chr8_+_56014949 Show fit	3.00	ENST00000327381.6	XKR4 Ensembl NCBI GeneCards UniProt NextProt Show fit	XK, Kell blood group complex subunit-related family, member 4
chr7_-_139876812 Show fit	2.77	ENST00000397560.2	JHDM1D Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine (K)-specific demethylase 7A
chr16_-_10674528 Show fit	2.73	ENST00000359543.3	EMP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	epithelial membrane protein 2
chr20_-_39317868 Show fit	2.53	ENST00000373313.2	MAFB Ensembl NCBI GeneCards UniProt NextProt Show fit	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr10_-_120514720 Show fit	2.45	ENST00000369151.3 ENST00000340214.4	CACUL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	CDK2-associated, cullin domain 1
chr2_+_28615669 Show fit	2.24	ENST00000379619.1 ENST00000264716.4	FOSL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	FOS-like antigen 2
chr12_-_15038779 Show fit	2.11	ENST00000228938.5 ENST00000539261.1	MGP Ensembl NCBI GeneCards UniProt NextProt Show fit	matrix Gla protein
chr3_-_21792838 Show fit	1.91	ENST00000281523.2	ZNF385D Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 385D
chr21_+_30671189 Show fit	1.76	ENST00000286800.3	BACH1 Ensembl NCBI GeneCards UniProt NextProt Show fit	BTB and CNC homology 1, basic leucine zipper transcription factor 1

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of UAAUGCU

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	5.2	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1	2.9	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3	2.7	GO:0070836	caveola assembly(GO:0070836)
0.8	2.5	GO:0035284	rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1	2.2	GO:0003334	keratinocyte development(GO:0003334)
0.1	2.1	GO:0001502	cartilage condensation(GO:0001502)
0.4	1.9	GO:0051138	positive regulation of NK T cell differentiation(GO:0051138)
0.2	1.9	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.3	1.7	GO:1900145	regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175)
0.2	1.7	GO:2001137	positive regulation of endocytic recycling(GO:2001137)

Showing 1 to 10 of 114 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	7.4	GO:0016363	nuclear matrix(GO:0016363)
0.0	4.5	GO:0005667	transcription factor complex(GO:0005667)
0.0	3.2	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	2.7	GO:0005901	caveola(GO:0005901)
0.0	2.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	1.9	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.3	1.7	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2	1.6	GO:0035976	AP1 complex(GO:0035976)
0.1	1.4	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	1.4	GO:0031461	cullin-RING ubiquitin ligase complex(GO:0031461)

Showing 1 to 10 of 46 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	8.0	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.2	5.5	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.3	3.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	3.1	GO:0001046	core promoter sequence-specific DNA binding(GO:0001046)
0.0	2.7	GO:0005178	integrin binding(GO:0005178)
0.0	2.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	2.1	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.2	1.8	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	1.8	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	1.7	GO:0032452	histone demethylase activity(GO:0032452)

Showing 1 to 10 of 87 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	7.7	PID IFNG PATHWAY	IFN-gamma pathway
0.1	4.4	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	3.4	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	2.2	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	1.6	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	1.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	1.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	1.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.3	PID ALK1 PATHWAY	ALK1 signaling events
0.0	1.2	PID IL4 2PATHWAY	IL4-mediated signaling events

Showing 1 to 10 of 26 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	5.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	2.7	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	2.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.7	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	1.6	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	1.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	1.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	1.4	REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases

Showing 1 to 10 of 28 entries

Results for UAAUGCU

Z-value: 0.00

Motif logo

miRNA associated with seed UAAUGCU

Activity profile of UAAUGCU motif

Sorted Z-values of UAAUGCU motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of UAAUGCU

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: