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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for UCACAUU

Z-value: 0.48

Motif logo

logo of

miRNA associated with seed UCACAUU

NamemiRBASE accession
hsa-miR-23a-3p
MIMAT0000078
hsa-miR-23b-3p
MIMAT0000418
hsa-miR-23c
MIMAT0018000
hsa-miR-130a-5p
MIMAT0004593

Activity profile of UCACAUU motif

Sorted Z-values of UCACAUU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_174256276 12.26 ENST00000296503.5
HMGB2
high mobility group box 2
chr12_+_104682496 12.16 ENST00000378070.4
TXNRD1
thioredoxin reductase 1
chr17_-_62658186 9.45 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr5_+_82767284 9.04 ENST00000265077.3
VCAN
versican
chr17_+_37026106 7.77 ENST00000318008.6
LASP1
LIM and SH3 protein 1
chr12_-_76953284 7.76 ENST00000547544.1
ENST00000393249.2
OSBPL8
oxysterol binding protein-like 8
chr5_+_162864575 7.61 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr12_-_46662772 7.23 ENST00000549049.1
ENST00000439706.1
ENST00000398637.5
SLC38A1
solute carrier family 38, member 1
chr17_-_29151794 7.21 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chr5_+_65222299 6.61 ENST00000284037.5
ERBB2IP
erbb2 interacting protein
chr20_+_39657454 6.40 ENST00000361337.2
TOP1
topoisomerase (DNA) I
chr12_+_104324112 6.10 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr14_-_64010046 6.08 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr1_+_26798955 5.95 ENST00000361427.5
HMGN2
high mobility group nucleosomal binding domain 2
chr3_-_182698381 5.89 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr8_+_126442563 5.77 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr3_-_113465065 5.59 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr6_-_24721054 5.56 ENST00000378119.4
C6orf62
chromosome 6 open reading frame 62
chr13_+_98605902 5.48 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
IPO5
importin 5
chr6_+_119215308 5.44 ENST00000229595.5
ASF1A
anti-silencing function 1A histone chaperone
chr10_+_89622870 5.30 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr11_-_76091986 5.08 ENST00000260045.3
PRKRIR
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr16_+_67596310 5.04 ENST00000264010.4
ENST00000401394.1
CTCF
CCCTC-binding factor (zinc finger protein)
chr1_+_112162381 5.00 ENST00000433097.1
ENST00000369709.3
ENST00000436150.2
RAP1A
RAP1A, member of RAS oncogene family
chr1_-_225615599 4.91 ENST00000421383.1
ENST00000272163.4
LBR
lamin B receptor
chrX_-_129244655 4.85 ENST00000335997.7
ELF4
E74-like factor 4 (ets domain transcription factor)
chr3_-_52713729 4.73 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
PBRM1
polybromo 1
chr17_+_45608430 4.67 ENST00000322157.4
NPEPPS
aminopeptidase puromycin sensitive
chr8_-_103876965 4.61 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr6_+_114178512 4.58 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr11_+_32112431 4.47 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr5_-_157002775 4.45 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr12_+_70636765 4.07 ENST00000552231.1
ENST00000229195.3
ENST00000547780.1
ENST00000418359.3
CNOT2
CCR4-NOT transcription complex, subunit 2
chr2_-_175113301 3.96 ENST00000344357.5
ENST00000284719.3
OLA1
Obg-like ATPase 1
chr2_-_200322723 3.90 ENST00000417098.1
SATB2
SATB homeobox 2
chr14_+_103058948 3.89 ENST00000262241.6
RCOR1
REST corepressor 1
chr3_+_196466710 3.88 ENST00000327134.3
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr4_+_39699664 3.87 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
UBE2K
ubiquitin-conjugating enzyme E2K
chr10_+_1095416 3.86 ENST00000358220.1
WDR37
WD repeat domain 37
chr4_-_185395672 3.72 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr4_-_40631859 3.71 ENST00000295971.7
ENST00000319592.4
RBM47
RNA binding motif protein 47
chrX_+_21958674 3.63 ENST00000404933.2
SMS
spermine synthase
chr11_+_34073195 3.62 ENST00000341394.4
CAPRIN1
cell cycle associated protein 1
chr10_+_93558069 3.62 ENST00000371627.4
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr12_-_10766184 3.58 ENST00000539554.1
ENST00000381881.2
ENST00000320756.2
MAGOHB
mago-nashi homolog B (Drosophila)
chr1_-_212004090 3.56 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr10_+_81107216 3.50 ENST00000394579.3
ENST00000225174.3
PPIF
peptidylprolyl isomerase F
chr1_+_24286287 3.41 ENST00000334351.7
ENST00000374468.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr19_+_1026298 3.36 ENST00000263097.4
CNN2
calponin 2
chr14_-_68141535 3.36 ENST00000554659.1
VTI1B
vesicle transport through interaction with t-SNAREs 1B
chr5_+_112312416 3.35 ENST00000389063.2
DCP2
decapping mRNA 2
chr11_+_74660278 3.34 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr14_+_73525144 3.34 ENST00000261973.7
ENST00000540173.1
RBM25
RNA binding motif protein 25
chr15_-_37390482 3.32 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr10_-_120840309 3.32 ENST00000369144.3
EIF3A
eukaryotic translation initiation factor 3, subunit A
chr9_-_74383799 3.29 ENST00000377044.4
TMEM2
transmembrane protein 2
chr10_+_11206925 3.27 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr1_-_205719295 3.16 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr1_+_198126093 3.10 ENST00000367385.4
ENST00000442588.1
ENST00000538004.1
NEK7
NIMA-related kinase 7
chr3_-_160283348 3.08 ENST00000334256.4
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr7_+_27779714 3.07 ENST00000265393.6
ENST00000409980.1
ENST00000433216.2
ENST00000396319.2
TAX1BP1
Tax1 (human T-cell leukemia virus type I) binding protein 1
chr9_+_110045537 3.05 ENST00000358015.3
RAD23B
RAD23 homolog B (S. cerevisiae)
chr9_-_127952032 3.05 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
PPP6C
protein phosphatase 6, catalytic subunit
chr6_-_16761678 2.98 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr20_+_31407692 2.98 ENST00000375571.5
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chr10_-_101989315 2.94 ENST00000370397.7
CHUK
conserved helix-loop-helix ubiquitous kinase
chr12_+_69004619 2.92 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B
RAP1B, member of RAS oncogene family
chr17_-_40761375 2.87 ENST00000543197.1
ENST00000309428.5
FAM134C
family with sequence similarity 134, member C
chr4_+_140222609 2.79 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr2_-_10952922 2.74 ENST00000272227.3
PDIA6
protein disulfide isomerase family A, member 6
chr6_+_15246501 2.73 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr4_-_141677267 2.73 ENST00000442267.2
TBC1D9
TBC1 domain family, member 9 (with GRAM domain)
chr3_+_30648066 2.70 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr13_+_73302047 2.69 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
BORA
bora, aurora kinase A activator
chr4_+_17616253 2.67 ENST00000237380.7
MED28
mediator complex subunit 28
chr1_-_150669500 2.67 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr12_+_122242597 2.66 ENST00000267197.5
SETD1B
SET domain containing 1B
chr6_+_138188551 2.64 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr5_+_34656331 2.61 ENST00000265109.3
RAI14
retinoic acid induced 14
chr6_-_82462425 2.60 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr8_+_20054878 2.58 ENST00000276390.2
ENST00000519667.1
ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr12_+_66217911 2.51 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr1_-_245027833 2.50 ENST00000444376.2
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr1_-_114355083 2.50 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chr1_-_68962782 2.49 ENST00000456315.2
DEPDC1
DEP domain containing 1
chr8_-_28243934 2.46 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395
zinc finger protein 395
chr10_-_65225722 2.44 ENST00000399251.1
JMJD1C
jumonji domain containing 1C
chr2_+_159313452 2.43 ENST00000389757.3
ENST00000389759.3
PKP4
plakophilin 4
chrX_+_146993449 2.42 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
FMR1
fragile X mental retardation 1
chr4_-_76598296 2.40 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr1_+_244214577 2.39 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr9_+_114423615 2.35 ENST00000374293.4
GNG10
guanine nucleotide binding protein (G protein), gamma 10
chr4_-_140098339 2.33 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr9_+_36572851 2.26 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr7_-_93520259 2.24 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr8_+_26240414 2.23 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr2_+_28974668 2.22 ENST00000296122.6
ENST00000395366.2
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr2_-_160472952 2.20 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr4_-_102268628 2.20 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr7_-_26240357 2.19 ENST00000354667.4
ENST00000356674.7
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr2_-_172017343 2.19 ENST00000431350.2
ENST00000360843.3
TLK1
tousled-like kinase 1
chr3_+_152879985 2.18 ENST00000323534.2
RAP2B
RAP2B, member of RAS oncogene family
chr1_-_38325256 2.18 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr7_+_114562172 2.16 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr5_-_131826457 2.14 ENST00000437654.1
ENST00000245414.4
IRF1
interferon regulatory factor 1
chr8_+_59465728 2.13 ENST00000260130.4
ENST00000422546.2
ENST00000447182.2
ENST00000413219.2
ENST00000424270.2
ENST00000523483.1
ENST00000520168.1
SDCBP
syndecan binding protein (syntenin)
chr14_+_60715928 2.10 ENST00000395076.4
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr7_-_123197733 2.09 ENST00000470123.1
ENST00000471770.1
NDUFA5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr13_-_50367057 2.09 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr7_+_99036543 2.09 ENST00000436336.2
ENST00000451876.1
ENST00000292476.5
CPSF4
cleavage and polyadenylation specific factor 4, 30kDa
chr1_-_108742957 2.06 ENST00000565488.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr5_-_176778523 2.04 ENST00000513877.1
ENST00000515209.1
ENST00000514458.1
ENST00000502560.1
LMAN2
lectin, mannose-binding 2
chr3_+_69812877 2.03 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr8_-_8751068 1.99 ENST00000276282.6
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr18_+_3451646 1.99 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr1_-_205290865 1.99 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr4_+_154387480 1.97 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr2_-_47168906 1.93 ENST00000444761.2
ENST00000409147.1
MCFD2
multiple coagulation factor deficiency 2
chr7_-_93633684 1.91 ENST00000222547.3
ENST00000425626.1
BET1
Bet1 golgi vesicular membrane trafficking protein
chr18_+_9913977 1.90 ENST00000400000.2
ENST00000340541.4
VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr1_-_65432171 1.89 ENST00000342505.4
JAK1
Janus kinase 1
chr10_+_85899196 1.87 ENST00000372134.3
GHITM
growth hormone inducible transmembrane protein
chr3_-_72496035 1.86 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr3_-_18466787 1.84 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr4_+_160188889 1.83 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr4_-_24586140 1.82 ENST00000336812.4
DHX15
DEAH (Asp-Glu-Ala-His) box helicase 15
chr4_-_103748880 1.81 ENST00000453744.2
ENST00000349311.8
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr4_+_41937131 1.79 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
TMEM33
transmembrane protein 33
chr14_+_55518349 1.72 ENST00000395468.4
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr22_-_18111499 1.72 ENST00000413576.1
ENST00000399796.2
ENST00000399798.2
ENST00000253413.5
ATP6V1E1
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
chr20_-_36156125 1.71 ENST00000397135.1
ENST00000397137.1
BLCAP
bladder cancer associated protein
chr10_+_93683519 1.70 ENST00000265990.6
BTAF1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
chr17_-_40428359 1.66 ENST00000293328.3
STAT5B
signal transducer and activator of transcription 5B
chr17_+_57784826 1.64 ENST00000262291.4
VMP1
vacuole membrane protein 1
chr3_-_133380731 1.64 ENST00000260810.5
TOPBP1
topoisomerase (DNA) II binding protein 1
chr20_+_62371206 1.63 ENST00000266077.2
SLC2A4RG
SLC2A4 regulator
chrX_-_20284958 1.62 ENST00000379565.3
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr10_-_99094458 1.59 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr1_-_86174065 1.56 ENST00000370574.3
ENST00000431532.2
ZNHIT6
zinc finger, HIT-type containing 6
chr10_+_115438920 1.56 ENST00000429617.1
ENST00000369331.4
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr6_+_110501344 1.56 ENST00000368932.1
CDC40
cell division cycle 40
chr8_-_103668114 1.55 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr15_-_60690163 1.54 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2
annexin A2
chr14_+_39735411 1.54 ENST00000603904.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr5_+_40679584 1.50 ENST00000302472.3
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr15_+_40532058 1.50 ENST00000260404.4
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr17_-_3749515 1.49 ENST00000158149.3
ENST00000389005.4
C17orf85
chromosome 17 open reading frame 85
chr3_+_107241783 1.47 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)
chr13_-_30169807 1.47 ENST00000380752.5
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr2_-_209119831 1.47 ENST00000345146.2
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr1_+_36621529 1.46 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr2_-_153574480 1.46 ENST00000410080.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chrX_+_46433193 1.46 ENST00000276055.3
CHST7
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
chr15_+_41709302 1.44 ENST00000389629.4
RTF1
Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr8_-_117886955 1.44 ENST00000297338.2
RAD21
RAD21 homolog (S. pombe)
chr7_+_116312411 1.43 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr1_+_93913713 1.41 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr22_+_38093005 1.38 ENST00000406386.3
TRIOBP
TRIO and F-actin binding protein
chr6_+_4021554 1.37 ENST00000337659.6
PRPF4B
pre-mRNA processing factor 4B
chr12_+_22778009 1.36 ENST00000266517.4
ENST00000335148.3
ETNK1
ethanolamine kinase 1
chr4_-_140223670 1.36 ENST00000394228.1
ENST00000539387.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr8_+_86376081 1.34 ENST00000285379.5
CA2
carbonic anhydrase II
chr17_+_34900737 1.34 ENST00000304718.4
ENST00000485685.2
GGNBP2
gametogenetin binding protein 2
chr10_+_60094735 1.31 ENST00000373910.4
UBE2D1
ubiquitin-conjugating enzyme E2D 1
chr1_-_39339777 1.27 ENST00000397572.2
MYCBP
MYC binding protein
chr13_+_43597269 1.25 ENST00000379221.2
DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chr2_+_163200598 1.23 ENST00000437150.2
ENST00000453113.2
GCA
grancalcin, EF-hand calcium binding protein
chr10_+_99079008 1.22 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr15_-_52861394 1.22 ENST00000563277.1
ENST00000566423.1
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr2_-_1748214 1.21 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN
peroxidasin homolog (Drosophila)
chr12_+_96588143 1.19 ENST00000228741.3
ENST00000547249.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr8_+_61591337 1.18 ENST00000423902.2
CHD7
chromodomain helicase DNA binding protein 7
chr6_+_89790490 1.18 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr11_+_124609823 1.17 ENST00000412681.2
NRGN
neurogranin (protein kinase C substrate, RC3)
chr2_+_120517174 1.15 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr16_-_48644061 1.13 ENST00000262384.3
N4BP1
NEDD4 binding protein 1
chr8_+_37620097 1.13 ENST00000328195.3
ENST00000523358.1
ENST00000523187.1
PROSC
proline synthetase co-transcribed homolog (bacterial)
chr12_-_9102549 1.12 ENST00000000412.3
M6PR
mannose-6-phosphate receptor (cation dependent)
chr8_-_122653630 1.12 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr10_-_125851961 1.11 ENST00000346248.5
CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr7_+_69064300 1.11 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr1_-_231560790 1.10 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr7_+_5938351 1.10 ENST00000325974.6
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr17_-_65241281 1.10 ENST00000358691.5
ENST00000580168.1
HELZ
helicase with zinc finger
chrX_-_132549506 1.06 ENST00000370828.3
GPC4
glypican 4
chr8_+_64081118 1.06 ENST00000539294.1
YTHDF3
YTH domain family, member 3
chr5_+_10353780 1.06 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
MARCH6
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chr17_+_28705921 1.05 ENST00000225719.4
CPD
carboxypeptidase D
chr17_-_62502639 1.04 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr11_+_86748863 1.04 ENST00000340353.7
TMEM135
transmembrane protein 135
chr12_+_111843749 1.04 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr8_+_95653373 1.03 ENST00000358397.5
ESRP1
epithelial splicing regulatory protein 1
chr10_+_43633914 1.03 ENST00000374466.3
ENST00000374464.1
CSGALNACT2
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chrX_-_109561294 1.03 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr16_-_89007491 1.02 ENST00000327483.5
ENST00000564416.1
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr4_-_74124502 1.01 ENST00000358602.4
ENST00000330838.6
ENST00000561029.1
ANKRD17
ankyrin repeat domain 17
chr6_+_143929307 1.01 ENST00000427704.2
ENST00000305766.6
PHACTR2
phosphatase and actin regulator 2
chr16_-_46723066 1.01 ENST00000299138.7
VPS35
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr4_+_129730779 0.98 ENST00000226319.6
PHF17
jade family PHD finger 1
chr18_+_60190226 0.98 ENST00000269499.5
ZCCHC2
zinc finger, CCHC domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of UCACAUU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.5 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
1.9 5.8 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
1.7 5.0 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
1.7 5.0 GO:0097327 response to antineoplastic agent(GO:0097327)
1.4 12.2 GO:0001887 selenium compound metabolic process(GO:0001887)
1.3 5.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.2 12.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
1.2 3.6 GO:0006597 spermine biosynthetic process(GO:0006597)
1.2 3.6 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.2 3.5 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
1.2 4.6 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
1.1 5.6 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
1.1 7.8 GO:0090204 protein localization to nuclear pore(GO:0090204)
1.1 3.3 GO:0002188 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
1.0 3.0 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.9 2.7 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.9 2.6 GO:0034146 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.8 2.5 GO:0003131 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.8 3.2 GO:0019046 release from viral latency(GO:0019046)
0.8 5.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.7 2.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.7 2.9 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.7 3.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.6 1.9 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.6 3.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.6 1.8 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.6 2.4 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.6 5.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.6 1.8 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.6 4.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.6 4.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.6 1.1 GO:0030820 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121)
0.5 2.1 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.5 2.1 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.5 1.5 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.5 1.5 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.5 2.9 GO:1902741 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.5 1.5 GO:0006097 glyoxylate cycle(GO:0006097)
0.5 3.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.5 3.9 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.5 6.5 GO:0040016 embryonic cleavage(GO:0040016)
0.5 2.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 1.3 GO:0042938 dipeptide transport(GO:0042938)
0.4 1.3 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.4 2.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.4 6.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.4 0.9 GO:0060920 atrioventricular node development(GO:0003162) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.4 2.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.4 0.8 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.4 2.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.4 1.7 GO:0000255 allantoin metabolic process(GO:0000255)
0.4 1.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.4 4.0 GO:0001866 NK T cell proliferation(GO:0001866)
0.4 1.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.4 13.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.4 2.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.4 5.9 GO:0045116 protein neddylation(GO:0045116)
0.4 1.5 GO:1903826 arginine transmembrane transport(GO:1903826)
0.4 5.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 3.9 GO:0070933 histone H4 deacetylation(GO:0070933)
0.3 2.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.3 1.0 GO:1903181 positive regulation of Wnt protein secretion(GO:0061357) regulation of late endosome to lysosome transport(GO:1902822) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of vacuolar transport(GO:1903336) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.3 5.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.3 1.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.3 0.9 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.3 1.4 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.3 0.8 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 1.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 1.4 GO:0030047 actin modification(GO:0030047)
0.3 0.8 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.3 1.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.3 1.9 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.3 1.6 GO:0048254 snoRNA localization(GO:0048254)
0.3 1.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 2.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 2.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 0.5 GO:0003274 endocardial cushion fusion(GO:0003274)
0.2 0.5 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.2 0.9 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.2 0.9 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 1.1 GO:0070295 renal water absorption(GO:0070295)
0.2 2.7 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 4.6 GO:0051764 actin crosslink formation(GO:0051764)
0.2 3.6 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.2 1.3 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956) negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.2 7.2 GO:0001504 neurotransmitter uptake(GO:0001504)
0.2 1.0 GO:0021764 amygdala development(GO:0021764)
0.2 1.6 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 1.0 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.2 1.7 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 0.6 GO:1902938 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.2 1.0 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 0.5 GO:0050923 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.2 4.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 3.1 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.2 0.5 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2 3.3 GO:0006465 signal peptide processing(GO:0006465)
0.2 2.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 0.8 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 3.9 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.7 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 3.2 GO:0019054 modulation by virus of host process(GO:0019054)
0.1 0.3 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 1.9 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 2.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253) stress granule assembly(GO:0034063)
0.1 1.0 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.9 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 3.0 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.1 0.3 GO:0016241 regulation of macroautophagy(GO:0016241)
0.1 4.3 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.8 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.8 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.4 GO:0002384 hepatic immune response(GO:0002384)
0.1 1.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 1.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 1.4 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.1 0.6 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.4 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.3 GO:0003175 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186)
0.1 0.6 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.1 0.4 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 1.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 1.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 0.6 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 0.6 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 6.1 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.1 3.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.7 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1 3.1 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.1 0.3 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 4.7 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 1.5 GO:0006004 fucose metabolic process(GO:0006004)
0.1 2.0 GO:0042493 response to drug(GO:0042493)
0.1 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.8 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 3.1 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.1 1.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 3.5 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.1 0.2 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.1 4.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 5.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 2.2 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 2.7 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 5.0 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.1 5.1 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 1.6 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.1 6.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 1.9 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 2.4 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.1 5.4 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.1 1.1 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 1.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 2.1 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.9 GO:0044818 mitotic G2 DNA damage checkpoint(GO:0007095) mitotic G2/M transition checkpoint(GO:0044818)
0.1 1.5 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 2.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 2.2 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 3.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.7 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 1.0 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.1 1.8 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 3.2 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 1.2 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.1 2.0 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.1 4.5 GO:0048208 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.3 GO:1903421 regulation of synaptic vesicle recycling(GO:1903421)
0.1 1.1 GO:0006518 peptide metabolic process(GO:0006518)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 2.0 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 2.8 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.0 1.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.5 GO:0060346 bone trabecula formation(GO:0060346)
0.0 2.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 1.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.3 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 2.2 GO:0046686 response to cadmium ion(GO:0046686)
0.0 3.7 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.2 GO:0060283 negative regulation of oocyte development(GO:0060283) regulation of oocyte maturation(GO:1900193) negative regulation of oocyte maturation(GO:1900194)
0.0 1.6 GO:0007566 embryo implantation(GO:0007566)
0.0 2.6 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.9 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.2 GO:0032383 dolichol metabolic process(GO:0019348) regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.5 GO:0098781 ncRNA transcription(GO:0098781)
0.0 0.4 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.6 GO:0043010 camera-type eye development(GO:0043010)
0.0 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.6 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 4.6 GO:0002576 platelet degranulation(GO:0002576)
0.0 3.1 GO:0045931 positive regulation of mitotic cell cycle(GO:0045931)
0.0 4.5 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 3.5 GO:0051168 nuclear export(GO:0051168)
0.0 0.1 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.6 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.3 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.8 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.8 GO:0006953 acute-phase response(GO:0006953)
0.0 1.4 GO:0010324 membrane invagination(GO:0010324)
0.0 0.6 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.1 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.2 GO:0021772 olfactory bulb development(GO:0021772)
0.0 0.1 GO:0034453 microtubule anchoring(GO:0034453)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
1.2 8.4 GO:0031415 NatA complex(GO:0031415)
0.8 2.4 GO:0019034 viral replication complex(GO:0019034)
0.6 3.9 GO:0070545 PeBoW complex(GO:0070545)
0.6 3.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.6 7.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.5 3.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.5 1.4 GO:0000798 nuclear cohesin complex(GO:0000798)
0.5 3.3 GO:0005787 signal peptidase complex(GO:0005787)
0.5 8.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.4 4.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.4 6.2 GO:0043073 germ cell nucleus(GO:0043073)
0.4 3.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.4 1.8 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.3 1.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.3 2.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.3 0.9 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.3 3.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 2.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 2.2 GO:0005955 calcineurin complex(GO:0005955)
0.2 4.3 GO:0032433 filopodium tip(GO:0032433)
0.2 0.9 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.2 4.9 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 2.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 3.6 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 2.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 2.2 GO:0072357 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.2 2.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 2.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 1.6 GO:0070761 pre-snoRNP complex(GO:0070761)
0.2 0.6 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 3.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.2 1.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.2 2.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 1.7 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.2 6.2 GO:0090544 BAF-type complex(GO:0090544)
0.2 0.9 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 3.6 GO:0000242 pericentriolar material(GO:0000242)
0.2 0.9 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 3.5 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 0.4 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 1.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.8 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.9 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 3.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 3.9 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 3.3 GO:0051233 spindle midzone(GO:0051233)
0.1 1.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.4 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 2.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.6 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 17.8 GO:0000793 condensed chromosome(GO:0000793)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.8 GO:0005638 lamin filament(GO:0005638)
0.1 10.9 GO:0005643 nuclear pore(GO:0005643)
0.1 12.8 GO:0001650 fibrillar center(GO:0001650)
0.1 9.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.3 GO:0097422 tubular endosome(GO:0097422)
0.1 9.9 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.7 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 4.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 5.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 6.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 6.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 1.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 2.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.1 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.1 1.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 6.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.4 GO:0042382 paraspeckles(GO:0042382)
0.1 1.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.6 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 4.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 4.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 3.4 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 3.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 2.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 1.5 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.0 11.7 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 3.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 3.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.9 GO:0099738 cell cortex region(GO:0099738)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 13.2 GO:0000785 chromatin(GO:0000785)
0.0 0.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 0.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 2.1 GO:0000922 spindle pole(GO:0000922)
0.0 2.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 1.4 GO:0005902 microvillus(GO:0005902)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 1.8 GO:0030496 midbody(GO:0030496)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.9 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
3.1 12.3 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
1.8 5.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
1.6 4.9 GO:0050613 delta14-sterol reductase activity(GO:0050613)
1.1 5.4 GO:0034046 poly(G) binding(GO:0034046)
1.1 6.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.8 2.5 GO:0035501 MH1 domain binding(GO:0035501)
0.7 2.9 GO:0008384 IkappaB kinase activity(GO:0008384)
0.7 2.9 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.7 2.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.7 2.7 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.7 4.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.6 8.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.6 1.9 GO:0033149 FFAT motif binding(GO:0033149)
0.6 6.1 GO:0046790 virion binding(GO:0046790)
0.5 6.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.5 10.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.5 1.5 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.4 3.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.4 5.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.4 1.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.4 4.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.4 2.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.4 1.5 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.3 1.0 GO:0035500 MH2 domain binding(GO:0035500)
0.3 3.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.3 5.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.3 3.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.3 6.4 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.3 9.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 5.9 GO:0097602 cullin family protein binding(GO:0097602)
0.3 2.2 GO:0030957 Tat protein binding(GO:0030957)
0.3 2.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 1.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.3 3.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.3 1.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 3.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 5.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 1.7 GO:0050815 phosphoserine binding(GO:0050815)
0.2 1.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.2 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 2.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 1.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.2 0.7 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.2 1.0 GO:0035591 signaling adaptor activity(GO:0035591)
0.2 1.0 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.2 4.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 1.6 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.2 1.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 1.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 0.9 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 1.3 GO:0004064 arylesterase activity(GO:0004064)
0.2 1.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 2.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 6.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 4.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.8 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 2.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.6 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.8 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 1.0 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 1.4 GO:0045159 myosin II binding(GO:0045159)
0.1 1.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.9 GO:0005537 mannose binding(GO:0005537)
0.1 3.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.6 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.4 GO:0036033 mediator complex binding(GO:0036033)
0.1 3.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 6.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 1.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 2.0 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.6 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 3.9 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1 4.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.3 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 1.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.6 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 3.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 2.2 GO:0005521 lamin binding(GO:0005521)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 3.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 5.8 GO:0019003 GDP binding(GO:0019003)
0.1 2.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 3.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 0.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 7.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 1.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 2.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 3.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.7 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 3.1 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 3.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.7 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.1 3.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.8 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.4 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 1.0 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.1 5.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 4.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.3 GO:0039552 RIG-I binding(GO:0039552)
0.0 2.4 GO:0070888 E-box binding(GO:0070888)
0.0 4.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0051538 iron-responsive element binding(GO:0030350) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 4.0 GO:0004386 helicase activity(GO:0004386)
0.0 0.9 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.1 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 1.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 7.8 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 8.7 GO:0003682 chromatin binding(GO:0003682)
0.0 0.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.4 GO:0005525 GTP binding(GO:0005525)
0.0 0.1 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 12.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 1.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 7.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 3.7 PID IL5 PATHWAY IL5-mediated signaling events
0.1 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 9.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 4.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 6.6 PID BMP PATHWAY BMP receptor signaling
0.1 10.9 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 1.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 3.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 3.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 4.9 PID PLK1 PATHWAY PLK1 signaling events
0.1 7.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 6.0 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.0 PID EPO PATHWAY EPO signaling pathway
0.1 2.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 3.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 4.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 12.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.6 5.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.5 14.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.4 6.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 4.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4 8.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.4 14.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.4 12.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3 7.9 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.3 3.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 12.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 5.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 3.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 3.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 9.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 6.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 3.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 4.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 5.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 4.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 3.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 4.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 3.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.4 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1 1.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 3.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 4.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 4.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.6 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 1.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 5.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 3.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 4.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 3.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 2.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 5.5 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.9 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 3.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.2 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.3 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis