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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for UCCAGUU

Z-value: 0.90

Motif logo

logo of

miRNA associated with seed UCCAGUU

NamemiRBASE accession
hsa-miR-145-5p
MIMAT0000437
hsa-miR-5195-3p
MIMAT0021127

Activity profile of UCCAGUU motif

Sorted Z-values of UCCAGUU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_159893507 25.89 ENST00000368096.1
TAGLN2
transgelin 2
chr8_+_98656336 25.42 ENST00000336273.3
MTDH
metadherin
chr12_-_92539614 23.07 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr1_+_86046433 22.94 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr18_+_3247413 21.41 ENST00000579226.1
ENST00000217652.3
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr11_-_102323489 20.70 ENST00000361236.3
TMEM123
transmembrane protein 123
chr3_+_180630090 18.30 ENST00000357559.4
ENST00000305586.7
FXR1
fragile X mental retardation, autosomal homolog 1
chr19_-_2456922 17.28 ENST00000582871.1
ENST00000325327.3
LMNB2
lamin B2
chr2_+_114647504 17.15 ENST00000263238.2
ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr1_-_94374946 16.11 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chr17_+_37026106 16.08 ENST00000318008.6
LASP1
LIM and SH3 protein 1
chr9_-_127952032 15.97 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
PPP6C
protein phosphatase 6, catalytic subunit
chrX_+_48432892 15.51 ENST00000376759.3
ENST00000430348.2
RBM3
RNA binding motif (RNP1, RRM) protein 3
chr10_-_74856608 15.04 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr9_+_114659046 14.97 ENST00000374279.3
UGCG
UDP-glucose ceramide glucosyltransferase
chr19_+_16187085 14.53 ENST00000300933.4
TPM4
tropomyosin 4
chr1_+_29063271 14.50 ENST00000373812.3
YTHDF2
YTH domain family, member 2
chr1_-_115259337 14.10 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr12_+_72148614 14.03 ENST00000261263.3
RAB21
RAB21, member RAS oncogene family
chr18_-_51751132 13.85 ENST00000256429.3
MBD2
methyl-CpG binding domain protein 2
chr16_+_67063036 13.69 ENST00000290858.6
ENST00000564034.1
CBFB
core-binding factor, beta subunit
chr2_-_174830430 13.27 ENST00000310015.6
ENST00000455789.2
SP3
Sp3 transcription factor
chr7_+_100770328 13.25 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr3_+_171758344 13.20 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr1_+_206557366 13.10 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr5_+_151151471 13.06 ENST00000394123.3
ENST00000543466.1
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr3_+_30648066 12.92 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr14_+_19553365 12.90 ENST00000409832.3
POTEG
POTE ankyrin domain family, member G
chr3_-_182698381 12.86 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr6_-_99797522 12.80 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr14_+_50359773 12.76 ENST00000298316.5
ARF6
ADP-ribosylation factor 6
chr11_-_46142948 12.34 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr3_-_195808952 12.28 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
TFRC
transferrin receptor
chrX_-_20284958 12.18 ENST00000379565.3
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr10_+_17686124 12.13 ENST00000377524.3
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr11_+_86748863 12.01 ENST00000340353.7
TMEM135
transmembrane protein 135
chr7_+_116139424 11.91 ENST00000222693.4
CAV2
caveolin 2
chrX_-_99891796 11.74 ENST00000373020.4
TSPAN6
tetraspanin 6
chr5_-_157002775 11.68 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr3_-_156877997 11.65 ENST00000295926.3
CCNL1
cyclin L1
chr1_+_10459111 11.40 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
PGD
phosphogluconate dehydrogenase
chr2_-_242212227 11.28 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
HDLBP
high density lipoprotein binding protein
chr9_+_131445928 11.26 ENST00000372692.4
SET
SET nuclear oncogene
chr16_-_85722530 11.14 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr5_+_86564739 10.80 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr1_-_70671216 10.73 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr18_-_18691739 10.18 ENST00000399799.2
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr1_-_94703118 9.96 ENST00000260526.6
ENST00000370217.3
ARHGAP29
Rho GTPase activating protein 29
chr11_+_63706444 9.92 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
NAA40
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chrX_-_108976521 9.80 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
ACSL4
acyl-CoA synthetase long-chain family member 4
chr15_+_52121822 9.74 ENST00000558455.1
ENST00000308580.7
TMOD3
tropomodulin 3 (ubiquitous)
chr2_+_36582857 9.71 ENST00000280527.2
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr5_+_115177178 9.62 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr14_-_20020272 9.62 ENST00000551509.1
POTEM
POTE ankyrin domain family, member M
chr7_+_77166592 9.61 ENST00000248594.6
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr16_+_16043406 9.59 ENST00000399410.3
ENST00000399408.2
ENST00000346370.5
ENST00000351154.5
ENST00000345148.5
ENST00000349029.5
ABCC1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
chr17_-_40306934 9.40 ENST00000592574.1
ENST00000550406.1
ENST00000547517.1
ENST00000393860.3
ENST00000346213.4
CTD-2132N18.3
RAB5C
Uncharacterized protein
RAB5C, member RAS oncogene family
chr11_-_6704513 9.36 ENST00000532203.1
ENST00000288937.6
MRPL17
mitochondrial ribosomal protein L17
chr1_-_38325256 9.22 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr7_+_5632436 9.03 ENST00000340250.6
ENST00000382361.3
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr15_+_67358163 9.00 ENST00000327367.4
SMAD3
SMAD family member 3
chr7_+_114562172 8.89 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr5_+_134094461 8.86 ENST00000452510.2
ENST00000354283.4
DDX46
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr3_-_113465065 8.74 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr7_-_131241361 8.66 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL
podocalyxin-like
chr4_-_24586140 8.49 ENST00000336812.4
DHX15
DEAH (Asp-Glu-Ala-His) box helicase 15
chr2_-_106810783 8.30 ENST00000283148.7
UXS1
UDP-glucuronate decarboxylase 1
chr17_-_46682321 8.09 ENST00000225648.3
ENST00000484302.2
HOXB6
homeobox B6
chr2_-_227664474 7.96 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr8_+_95732095 7.96 ENST00000414645.2
DPY19L4
dpy-19-like 4 (C. elegans)
chr11_+_9685604 7.84 ENST00000447399.2
ENST00000318950.6
SWAP70
SWAP switching B-cell complex 70kDa subunit
chr1_-_183604794 7.80 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr4_-_69215699 7.74 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTHDC1
YTH domain containing 1
chr1_+_167691191 7.72 ENST00000392121.3
ENST00000474859.1
MPZL1
myelin protein zero-like 1
chr5_-_39425068 7.52 ENST00000515700.1
ENST00000339788.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr6_+_143929307 7.52 ENST00000427704.2
ENST00000305766.6
PHACTR2
phosphatase and actin regulator 2
chr17_-_60142609 7.47 ENST00000397786.2
MED13
mediator complex subunit 13
chr11_+_34073195 7.39 ENST00000341394.4
CAPRIN1
cell cycle associated protein 1
chr11_+_9406169 7.34 ENST00000379719.3
ENST00000527431.1
IPO7
importin 7
chr1_+_218519577 7.28 ENST00000366930.4
ENST00000366929.4
TGFB2
transforming growth factor, beta 2
chr12_-_120687948 7.27 ENST00000458477.2
PXN
paxillin
chr3_+_179370517 7.25 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr20_+_19867150 7.21 ENST00000255006.6
RIN2
Ras and Rab interactor 2
chr4_-_25864581 7.14 ENST00000399878.3
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr1_-_19811962 7.04 ENST00000375142.1
ENST00000264202.6
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr2_+_9346892 6.98 ENST00000281419.3
ENST00000315273.4
ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr19_-_42759300 6.96 ENST00000222329.4
ERF
Ets2 repressor factor
chr10_+_5454505 6.95 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr1_-_205719295 6.77 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr3_+_57994127 6.71 ENST00000490882.1
ENST00000295956.4
ENST00000358537.3
ENST00000429972.2
ENST00000348383.5
ENST00000357272.4
FLNB
filamin B, beta
chr16_+_69221028 6.70 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr1_-_1822495 6.69 ENST00000378609.4
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr1_+_116184566 6.67 ENST00000355485.2
ENST00000369510.4
VANGL1
VANGL planar cell polarity protein 1
chr20_+_61427797 6.62 ENST00000370487.3
MRGBP
MRG/MORF4L binding protein
chr1_-_25291475 6.58 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr5_-_133304473 6.56 ENST00000231512.3
C5orf15
chromosome 5 open reading frame 15
chr3_-_189838670 6.45 ENST00000319332.5
LEPREL1
leprecan-like 1
chr3_+_58291965 6.38 ENST00000445193.3
ENST00000295959.5
ENST00000466547.1
RPP14
ribonuclease P/MRP 14kDa subunit
chr12_-_46766577 6.35 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr1_+_193091080 6.29 ENST00000367435.3
CDC73
cell division cycle 73
chr6_-_111804393 6.21 ENST00000368802.3
ENST00000368805.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr5_+_14143728 6.19 ENST00000344204.4
ENST00000537187.1
TRIO
trio Rho guanine nucleotide exchange factor
chr3_+_112709804 6.13 ENST00000383677.3
GTPBP8
GTP-binding protein 8 (putative)
chr10_+_70883908 6.02 ENST00000263559.6
ENST00000395098.1
ENST00000546041.1
ENST00000541711.1
VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr12_-_76478686 6.01 ENST00000261182.8
NAP1L1
nucleosome assembly protein 1-like 1
chr14_+_67707826 5.93 ENST00000261681.4
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr1_-_155232047 5.80 ENST00000302631.3
SCAMP3
secretory carrier membrane protein 3
chr5_-_77844974 5.79 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr17_+_18761417 5.76 ENST00000419284.2
ENST00000268835.2
ENST00000412418.1
ENST00000575228.1
ENST00000575102.1
ENST00000536323.1
PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr2_-_201828356 5.74 ENST00000234296.2
ORC2
origin recognition complex, subunit 2
chr18_+_2655692 5.65 ENST00000320876.6
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr9_+_80912059 5.64 ENST00000347159.2
ENST00000376588.3
PSAT1
phosphoserine aminotransferase 1
chr7_+_130126012 5.63 ENST00000341441.5
MEST
mesoderm specific transcript
chr2_-_131267239 5.50 ENST00000451531.2
POTEI
POTE ankyrin domain family, member I
chr2_+_228336849 5.35 ENST00000409979.2
ENST00000310078.8
AGFG1
ArfGAP with FG repeats 1
chr7_+_5938351 5.34 ENST00000325974.6
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr3_-_134093395 5.30 ENST00000249883.5
AMOTL2
angiomotin like 2
chr10_-_118032697 5.28 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr7_-_10979750 5.17 ENST00000339600.5
NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr12_+_96588143 5.15 ENST00000228741.3
ENST00000547249.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr17_+_45727204 5.11 ENST00000290158.4
KPNB1
karyopherin (importin) beta 1
chr20_-_62601218 5.04 ENST00000369888.1
ZNF512B
zinc finger protein 512B
chr6_+_7107999 5.04 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr1_+_39456895 5.03 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1
akirin 1
chr11_-_65381643 5.03 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr12_+_53848505 5.00 ENST00000552819.1
ENST00000455667.3
PCBP2
poly(rC) binding protein 2
chrX_+_70752917 4.97 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr17_-_79479789 4.92 ENST00000571691.1
ENST00000571721.1
ENST00000573283.1
ENST00000575842.1
ENST00000575087.1
ENST00000570382.1
ENST00000331925.2
ACTG1
actin, gamma 1
chr9_-_14314066 4.86 ENST00000397575.3
NFIB
nuclear factor I/B
chr7_-_5570229 4.84 ENST00000331789.5
ACTB
actin, beta
chr5_-_121413974 4.80 ENST00000231004.4
LOX
lysyl oxidase
chr14_-_75179774 4.76 ENST00000555249.1
ENST00000556202.1
ENST00000356357.4
ENST00000338772.5
AREL1
AC007956.1
apoptosis resistant E3 ubiquitin protein ligase 1
Full-length cDNA 5-PRIME end of clone CS0CAP004YO05 of Thymus of Homo sapiens (human); Uncharacterized protein
chrX_+_154299753 4.74 ENST00000369459.2
ENST00000369462.1
ENST00000411985.1
ENST00000399042.1
BRCC3
BRCA1/BRCA2-containing complex, subunit 3
chr15_+_41523335 4.73 ENST00000334660.5
CHP1
calcineurin-like EF-hand protein 1
chrX_+_100663243 4.61 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr18_-_45456930 4.53 ENST00000262160.6
ENST00000587269.1
SMAD2
SMAD family member 2
chr4_+_146402925 4.52 ENST00000302085.4
SMAD1
SMAD family member 1
chr10_+_112631547 4.51 ENST00000280154.7
ENST00000393104.2
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr18_+_9913977 4.44 ENST00000400000.2
ENST00000340541.4
VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr10_+_82213904 4.39 ENST00000429989.3
TSPAN14
tetraspanin 14
chr13_+_73632897 4.27 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr12_-_125348448 4.21 ENST00000339570.5
SCARB1
scavenger receptor class B, member 1
chr7_+_94285637 4.17 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr15_-_73076030 4.03 ENST00000311669.8
ADPGK
ADP-dependent glucokinase
chr9_-_110251836 4.01 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr16_-_4987065 3.98 ENST00000590782.2
ENST00000345988.2
PPL
periplakin
chr7_+_129710350 3.96 ENST00000335420.5
ENST00000463413.1
KLHDC10
kelch domain containing 10
chr8_-_119124045 3.93 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chrX_+_100645812 3.91 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A
RPL36A-HNRNPH2
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr6_+_25279651 3.90 ENST00000329474.6
LRRC16A
leucine rich repeat containing 16A
chr19_-_11308190 3.83 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KANK2
KN motif and ankyrin repeat domains 2
chr4_+_184020398 3.81 ENST00000403733.3
ENST00000378925.3
WWC2
WW and C2 domain containing 2
chr8_-_68255912 3.81 ENST00000262215.3
ENST00000519436.1
ARFGEF1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr2_+_121103706 3.74 ENST00000295228.3
INHBB
inhibin, beta B
chr5_+_174905398 3.55 ENST00000321442.5
SFXN1
sideroflexin 1
chr8_-_23712312 3.50 ENST00000290271.2
STC1
stanniocalcin 1
chr11_+_76494253 3.49 ENST00000333090.4
TSKU
tsukushi, small leucine rich proteoglycan
chr8_-_42751820 3.41 ENST00000526349.1
ENST00000527424.1
ENST00000534961.1
ENST00000319073.4
RNF170
ring finger protein 170
chr16_-_56485257 3.41 ENST00000300291.5
NUDT21
nudix (nucleoside diphosphate linked moiety X)-type motif 21
chr6_+_76458909 3.40 ENST00000369981.3
ENST00000369985.4
MYO6
myosin VI
chr17_+_72983674 3.38 ENST00000337231.5
CDR2L
cerebellar degeneration-related protein 2-like
chr4_-_68566832 3.29 ENST00000420827.2
ENST00000322244.5
UBA6
ubiquitin-like modifier activating enzyme 6
chr6_+_134274322 3.27 ENST00000367871.1
ENST00000237264.4
TBPL1
TBP-like 1
chr12_+_111843749 3.18 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr9_+_128509624 3.15 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chr4_-_102268628 3.13 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr17_+_1733276 3.12 ENST00000254719.5
RPA1
replication protein A1, 70kDa
chrX_-_119445263 3.11 ENST00000309720.5
TMEM255A
transmembrane protein 255A
chr8_-_6420930 3.04 ENST00000325203.5
ANGPT2
angiopoietin 2
chr8_-_28243934 3.03 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395
zinc finger protein 395
chr9_-_123964114 3.02 ENST00000373840.4
RAB14
RAB14, member RAS oncogene family
chr14_-_78083112 3.01 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr2_+_136499179 2.93 ENST00000272638.9
UBXN4
UBX domain protein 4
chr12_+_49761224 2.93 ENST00000553127.1
ENST00000321898.6
SPATS2
spermatogenesis associated, serine-rich 2
chr20_+_51588873 2.91 ENST00000371497.5
TSHZ2
teashirt zinc finger homeobox 2
chr22_-_42915788 2.89 ENST00000323013.6
RRP7A
ribosomal RNA processing 7 homolog A (S. cerevisiae)
chr19_-_4540486 2.84 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chr4_-_140098339 2.82 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr20_-_48770174 2.82 ENST00000341698.2
TMEM189-UBE2V1
TMEM189-UBE2V1 readthrough
chr17_+_57970469 2.80 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr12_-_31744031 2.70 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr20_-_48729670 2.67 ENST00000371657.5
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr2_+_204571198 2.58 ENST00000374481.3
ENST00000458610.2
ENST00000324106.8
CD28
CD28 molecule
chr6_-_11232891 2.56 ENST00000379433.5
ENST00000379446.5
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr19_-_47220335 2.52 ENST00000601806.1
ENST00000593363.1
ENST00000598633.1
ENST00000595515.1
ENST00000433867.1
PRKD2
protein kinase D2
chr7_-_92463210 2.51 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr22_+_31795509 2.50 ENST00000331457.4
DRG1
developmentally regulated GTP binding protein 1
chr2_-_24149977 2.48 ENST00000238789.5
ATAD2B
ATPase family, AAA domain containing 2B
chr1_+_89149905 2.46 ENST00000316005.7
ENST00000370521.3
ENST00000370505.3
PKN2
protein kinase N2
chr12_+_22778009 2.45 ENST00000266517.4
ENST00000335148.3
ETNK1
ethanolamine kinase 1
chrX_+_73641286 2.44 ENST00000587091.1
SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
chr11_-_33183006 2.42 ENST00000524827.1
ENST00000323959.4
ENST00000431742.2
CSTF3
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
chr12_+_58087901 2.39 ENST00000315970.7
ENST00000547079.1
ENST00000439210.2
ENST00000389146.6
ENST00000413095.2
ENST00000551035.1
ENST00000257966.8
ENST00000435406.2
ENST00000550372.1
ENST00000389142.5
OS9
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr17_-_38721711 2.34 ENST00000578085.1
ENST00000246657.2
CCR7
chemokine (C-C motif) receptor 7
chr2_+_204192942 2.29 ENST00000295851.5
ENST00000261017.5
ABI2
abl-interactor 2
chr17_-_1359443 2.28 ENST00000574295.1
ENST00000398970.5
ENST00000300574.2
CRK
v-crk avian sarcoma virus CT10 oncogene homolog
chr21_-_28338732 2.24 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chrX_-_3631635 2.24 ENST00000262848.5
PRKX
protein kinase, X-linked
chr7_-_83824169 2.19 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_-_13372395 2.05 ENST00000276297.4
ENST00000511869.1
DLC1
deleted in liver cancer 1

Network of associatons between targets according to the STRING database.

First level regulatory network of UCCAGUU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
5.0 20.2 GO:0003274 endocardial cushion fusion(GO:0003274)
5.0 15.0 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
4.4 13.3 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
4.0 16.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
3.8 23.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
3.8 11.4 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
2.9 22.9 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
2.7 16.3 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
2.7 8.0 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
2.6 7.8 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
2.5 10.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
2.4 22.0 GO:0032534 regulation of microvillus assembly(GO:0032534)
2.2 21.6 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
2.1 14.5 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
1.9 15.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
1.8 7.3 GO:0035523 protein K29-linked deubiquitination(GO:0035523) maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
1.8 9.0 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
1.8 23.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
1.7 12.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
1.7 6.8 GO:0019046 release from viral latency(GO:0019046)
1.7 5.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
1.6 9.6 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
1.5 4.5 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
1.5 4.5 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
1.4 7.0 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
1.4 5.6 GO:0007498 mesoderm development(GO:0007498)
1.4 4.2 GO:0015920 lipopolysaccharide transport(GO:0015920)
1.4 11.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
1.3 1.3 GO:0072190 ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
1.3 1.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.3 4.0 GO:0007500 mesodermal cell fate determination(GO:0007500) negative regulation of muscle hyperplasia(GO:0014740)
1.3 13.1 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
1.3 20.7 GO:0045793 positive regulation of cell size(GO:0045793)
1.3 5.1 GO:0031291 Ran protein signal transduction(GO:0031291)
1.3 3.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.3 3.8 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
1.3 5.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
1.2 3.7 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.2 1.2 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
1.2 11.7 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
1.2 3.5 GO:0061073 ciliary body morphogenesis(GO:0061073)
1.1 5.6 GO:0042816 vitamin B6 metabolic process(GO:0042816)
1.1 3.3 GO:0021764 amygdala development(GO:0021764)
1.1 8.7 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
1.1 6.3 GO:0032328 alanine transport(GO:0032328)
1.0 3.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
1.0 8.6 GO:0001675 acrosome assembly(GO:0001675)
0.9 15.0 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.9 2.8 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.9 16.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.8 11.7 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.8 12.9 GO:0045116 protein neddylation(GO:0045116)
0.8 8.0 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.8 4.7 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.8 2.3 GO:2000525 dendritic cell dendrite assembly(GO:0097026) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.8 7.8 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.8 3.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.8 3.8 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.8 3.0 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.8 3.0 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.7 9.6 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.7 9.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.7 5.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.7 11.3 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.7 4.9 GO:0021960 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) anterior commissure morphogenesis(GO:0021960) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.7 12.3 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.7 14.2 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.7 1.3 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.7 5.9 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.6 2.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.6 4.7 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.6 9.9 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.6 7.0 GO:0051451 myoblast migration(GO:0051451)
0.6 39.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.6 4.5 GO:0031053 primary miRNA processing(GO:0031053)
0.6 5.6 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.5 3.2 GO:0007386 compartment pattern specification(GO:0007386)
0.5 6.3 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.5 2.5 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.5 1.4 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.5 5.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.5 12.2 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.5 1.9 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.4 0.9 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.4 2.2 GO:0048880 sensory system development(GO:0048880)
0.4 4.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 11.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.4 2.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.4 9.4 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.4 7.3 GO:0007172 signal complex assembly(GO:0007172)
0.4 3.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.4 2.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 6.7 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.4 1.4 GO:1903826 arginine transmembrane transport(GO:1903826)
0.4 6.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.4 12.0 GO:0032094 response to food(GO:0032094)
0.3 12.1 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.3 5.0 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.3 1.7 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.3 9.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.3 27.2 GO:0070527 platelet aggregation(GO:0070527)
0.3 1.8 GO:0055064 chloride ion homeostasis(GO:0055064)
0.3 5.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 1.5 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.3 1.8 GO:0035137 embryonic hindlimb morphogenesis(GO:0035116) hindlimb morphogenesis(GO:0035137)
0.3 0.9 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.3 6.7 GO:0003334 keratinocyte development(GO:0003334)
0.3 3.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.3 1.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.3 4.5 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.3 7.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.3 1.6 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.3 11.1 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.3 2.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 2.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.2 9.7 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.2 7.2 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.2 10.2 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.2 2.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 5.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.2 GO:0016584 nucleosome positioning(GO:0016584)
0.2 7.6 GO:0006270 DNA replication initiation(GO:0006270)
0.2 40.6 GO:0002576 platelet degranulation(GO:0002576)
0.2 0.5 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 2.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 7.5 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.2 2.5 GO:0043297 apical junction assembly(GO:0043297)
0.2 2.6 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.2 8.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 2.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 1.8 GO:0051956 negative regulation of amino acid transport(GO:0051956)
0.2 0.8 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.2 6.3 GO:0006301 postreplication repair(GO:0006301)
0.2 0.7 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 1.5 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.2 8.6 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.2 0.7 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.2 12.8 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.2 13.7 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 4.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 9.2 GO:0046686 response to cadmium ion(GO:0046686)
0.1 2.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.1 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 1.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 2.2 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.1 3.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.5 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.9 GO:0060033 anatomical structure regression(GO:0060033)
0.1 8.8 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 2.8 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 12.0 GO:0016575 histone deacetylation(GO:0016575)
0.1 4.2 GO:0035329 hippo signaling(GO:0035329)
0.1 2.9 GO:0001825 blastocyst formation(GO:0001825)
0.1 0.5 GO:0042695 thelarche(GO:0042695) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744)
0.1 2.0 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 0.6 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.9 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 4.0 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 5.5 GO:0001895 retina homeostasis(GO:0001895)
0.1 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.4 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 1.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.8 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 6.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 1.4 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 3.5 GO:0006826 iron ion transport(GO:0006826)
0.1 21.6 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 0.8 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 3.0 GO:0090382 phagosome maturation(GO:0090382)
0.1 6.4 GO:0043473 pigmentation(GO:0043473)
0.1 3.2 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 6.6 GO:0016573 histone acetylation(GO:0016573)
0.0 0.1 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.7 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 2.4 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 4.0 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0098904 pulmonary valve formation(GO:0003193) atrial ventricular junction remodeling(GO:0003294) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of AV node cell action potential(GO:0098904) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.0 0.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 1.3 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 3.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 3.0 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.0 0.2 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.0 1.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.5 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.3 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.6 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 15.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
4.0 12.1 GO:0033565 ESCRT-0 complex(GO:0033565)
3.6 25.4 GO:0046581 intercellular canaliculus(GO:0046581)
3.0 9.0 GO:0044393 microspike(GO:0044393)
2.8 11.1 GO:0000811 GINS complex(GO:0000811)
2.3 20.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
2.0 6.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)
1.9 17.3 GO:0005638 lamin filament(GO:0005638)
1.9 5.7 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
1.8 14.0 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
1.7 8.5 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
1.7 13.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
1.6 8.0 GO:0005899 insulin receptor complex(GO:0005899)
1.4 5.8 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
1.3 24.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
1.2 8.7 GO:0031415 NatA complex(GO:0031415)
1.2 14.8 GO:0044327 dendritic spine head(GO:0044327)
1.1 10.2 GO:0032059 bleb(GO:0032059)
0.9 12.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.9 5.6 GO:0001740 Barr body(GO:0001740)
0.9 9.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.9 9.6 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.9 12.8 GO:0090543 Flemming body(GO:0090543)
0.8 3.0 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.8 9.8 GO:0097433 dense body(GO:0097433)
0.7 7.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.7 12.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.6 1.9 GO:0031213 RSF complex(GO:0031213)
0.6 6.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.6 4.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.6 4.7 GO:0070552 BRISC complex(GO:0070552)
0.5 2.7 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.5 6.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.5 12.9 GO:0031528 microvillus membrane(GO:0031528)
0.5 5.9 GO:0035749 myelin sheath adaxonal region(GO:0035749) lateral loop(GO:0043219)
0.5 6.4 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.5 2.4 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.4 6.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.4 13.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.4 11.9 GO:0002080 acrosomal membrane(GO:0002080)
0.4 34.5 GO:0005811 lipid particle(GO:0005811)
0.4 3.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.4 5.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.4 18.3 GO:0043034 costamere(GO:0043034)
0.4 2.9 GO:0042382 paraspeckles(GO:0042382)
0.3 3.1 GO:0005955 calcineurin complex(GO:0005955)
0.3 1.7 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 6.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3 5.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 12.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 25.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.3 5.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.3 6.6 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.3 24.6 GO:0016459 myosin complex(GO:0016459)
0.2 9.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 7.5 GO:0016592 mediator complex(GO:0016592)
0.2 13.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 13.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 9.6 GO:0002102 podosome(GO:0002102)
0.2 18.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 1.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.2 21.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.2 0.9 GO:0089701 U2AF(GO:0089701)
0.2 14.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 2.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 19.4 GO:0015934 large ribosomal subunit(GO:0015934)
0.2 4.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 2.3 GO:0031209 SCAR complex(GO:0031209)
0.2 10.4 GO:0015030 Cajal body(GO:0015030)
0.2 2.3 GO:0071141 SMAD protein complex(GO:0071141)
0.2 1.9 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 1.1 GO:0005915 zonula adherens(GO:0005915)
0.1 12.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 14.7 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 0.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 4.0 GO:0030057 desmosome(GO:0030057)
0.1 7.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 3.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 12.3 GO:0005643 nuclear pore(GO:0005643)
0.1 4.8 GO:0005581 collagen trimer(GO:0005581)
0.1 2.9 GO:0030686 90S preribosome(GO:0030686)
0.1 1.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 0.4 GO:0043196 varicosity(GO:0043196)
0.1 2.3 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 4.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 5.0 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.1 1.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.8 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.1 GO:0032420 stereocilium(GO:0032420)
0.1 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 17.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 2.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 14.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 4.1 GO:0005903 brush border(GO:0005903)
0.0 1.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 4.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.5 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 2.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 5.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 3.6 GO:0030027 lamellipodium(GO:0030027)
0.0 8.7 GO:0016607 nuclear speck(GO:0016607)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 3.9 GO:0005813 centrosome(GO:0005813)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 1.1 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.2 GO:0005840 ribosome(GO:0005840)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
3.8 11.4 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
3.2 12.9 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
3.2 9.6 GO:0015235 cobalamin transporter activity(GO:0015235)
3.0 15.0 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
2.4 7.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
2.4 7.3 GO:1904288 BAT3 complex binding(GO:1904288)
2.0 9.9 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
1.8 9.0 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
1.7 18.8 GO:0033592 RNA strand annealing activity(GO:0033592)
1.7 22.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
1.7 6.7 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
1.7 5.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
1.5 4.4 GO:0033149 FFAT motif binding(GO:0033149)
1.4 13.9 GO:0003696 satellite DNA binding(GO:0003696)
1.4 5.5 GO:0034186 apolipoprotein A-I binding(GO:0034186)
1.3 5.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
1.1 8.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
1.1 12.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
1.0 3.0 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.0 3.9 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
1.0 5.8 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
1.0 17.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.9 2.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.9 32.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.8 2.5 GO:0098770 FBXO family protein binding(GO:0098770)
0.8 5.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.8 4.0 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.8 12.8 GO:0031996 thioesterase binding(GO:0031996)
0.8 6.8 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.8 10.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.8 5.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.7 9.8 GO:0030957 Tat protein binding(GO:0030957)
0.7 16.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.7 9.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.7 11.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.7 9.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.7 25.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.7 2.0 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.5 3.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.5 7.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.5 1.5 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.5 1.4 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.5 9.1 GO:0097602 cullin family protein binding(GO:0097602)
0.5 4.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.5 7.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.5 1.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.4 8.0 GO:0000030 mannosyltransferase activity(GO:0000030)
0.4 18.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.4 1.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.4 1.6 GO:0038132 neuregulin binding(GO:0038132)
0.4 13.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 6.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.4 9.0 GO:0017166 vinculin binding(GO:0017166)
0.4 1.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.3 26.5 GO:0019003 GDP binding(GO:0019003)
0.3 8.3 GO:0070403 NAD+ binding(GO:0070403)
0.3 11.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.3 7.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 3.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 1.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 2.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.3 4.8 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.3 12.3 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.3 12.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 2.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.3 10.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.3 12.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.3 5.6 GO:0008483 transaminase activity(GO:0008483)
0.3 6.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.2 5.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 24.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 25.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 3.0 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.2 5.0 GO:0004697 protein kinase C activity(GO:0004697)
0.2 4.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.2 1.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.2 0.9 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 15.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 1.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 2.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 5.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 11.8 GO:0008026 ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035)
0.2 2.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 17.1 GO:0008565 protein transporter activity(GO:0008565)
0.2 2.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 1.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 2.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 12.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 4.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 9.7 GO:0097110 scaffold protein binding(GO:0097110)
0.1 57.9 GO:0045296 cadherin binding(GO:0045296)
0.1 0.7 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 6.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 6.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 13.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.7 GO:0031489 myosin V binding(GO:0031489)
0.1 1.2 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505) sequence-specific single stranded DNA binding(GO:0098847)
0.1 0.8 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 5.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 3.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 10.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 4.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.9 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 1.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 14.1 GO:0003924 GTPase activity(GO:0003924)
0.1 8.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 42.0 GO:0003712 transcription cofactor activity(GO:0003712)
0.1 6.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 41.7 GO:0005198 structural molecule activity(GO:0005198)
0.1 0.5 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 4.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 2.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.2 GO:0042393 histone binding(GO:0042393)
0.1 0.4 GO:0050733 RS domain binding(GO:0050733)
0.1 1.3 GO:0071949 FAD binding(GO:0071949)
0.0 7.5 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 1.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0086078 gap junction hemi-channel activity(GO:0055077) gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.0 3.5 GO:0005525 GTP binding(GO:0005525)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 3.0 GO:0002020 protease binding(GO:0002020)
0.0 0.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 16.4 GO:0003723 RNA binding(GO:0003723)
0.0 0.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 7.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.2 GO:0004713 protein tyrosine kinase activity(GO:0004713)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 16.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.7 20.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6 14.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.6 12.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.6 7.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.5 14.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.5 26.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.4 8.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.4 12.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.4 22.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.4 28.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.3 14.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 40.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.3 15.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 12.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.3 14.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.3 11.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.3 6.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 30.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 13.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 2.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 16.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 7.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 5.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 2.3 PID ALK2 PATHWAY ALK2 signaling events
0.2 5.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.2 PID RHOA PATHWAY RhoA signaling pathway
0.1 32.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.7 PID IL1 PATHWAY IL1-mediated signaling events
0.1 4.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 16.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 3.1 PID ATR PATHWAY ATR signaling pathway
0.1 1.9 PID ENDOTHELIN PATHWAY Endothelins
0.1 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 14.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
1.0 8.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.7 11.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.6 7.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.6 10.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.6 24.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.6 12.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.5 9.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4 16.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.4 31.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.4 12.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.3 5.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.3 15.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.3 13.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3 8.5 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.3 3.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 3.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 5.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 5.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 9.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 6.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 9.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 4.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 2.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 2.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 14.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 12.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 5.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 7.5 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.2 2.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 5.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 3.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 3.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 5.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 4.9 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 5.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 3.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 4.8 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 2.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 17.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 7.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 5.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 3.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 0.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 4.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 5.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 3.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 7.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 6.2 REACTOME DNA REPAIR Genes involved in DNA Repair
0.1 1.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 4.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 7.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 5.5 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis