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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for UGCAUAG

Z-value: 0.46

Motif logo

logo of

miRNA associated with seed UGCAUAG

NamemiRBASE accession
hsa-miR-153-3p
MIMAT0000439

Activity profile of UGCAUAG motif

Sorted Z-values of UGCAUAG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_10199468 29.14 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr8_+_24772455 24.02 ENST00000433454.2
NEFM
neurofilament, medium polypeptide
chr8_+_80523321 22.95 ENST00000518111.1
STMN2
stathmin-like 2
chr3_+_111717511 20.39 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr5_+_140868717 17.36 ENST00000252087.1
PCDHGC5
protocadherin gamma subfamily C, 5
chr5_+_140739537 17.03 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr5_+_140864649 16.90 ENST00000306593.1
PCDHGC4
protocadherin gamma subfamily C, 4
chr5_+_140749803 16.48 ENST00000576222.1
PCDHGB3
protocadherin gamma subfamily B, 3
chr10_-_15413035 15.86 ENST00000378116.4
ENST00000455654.1
FAM171A1
family with sequence similarity 171, member A1
chr12_+_79258547 15.73 ENST00000457153.2
SYT1
synaptotagmin I
chr5_+_140729649 15.58 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr5_+_140797296 15.45 ENST00000398594.2
PCDHGB7
protocadherin gamma subfamily B, 7
chr5_+_140762268 15.34 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr5_+_140772381 14.42 ENST00000398604.2
PCDHGA8
protocadherin gamma subfamily A, 8
chr3_+_49591881 13.60 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr10_-_81205373 13.45 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr5_+_140734570 12.56 ENST00000571252.1
PCDHGA4
protocadherin gamma subfamily A, 4
chr5_+_140743859 12.30 ENST00000518069.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr5_+_140753444 12.12 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr17_-_8066250 12.11 ENST00000488857.1
ENST00000481878.1
ENST00000316509.6
ENST00000498285.1
VAMP2
RP11-599B13.6
vesicle-associated membrane protein 2 (synaptobrevin 2)
Uncharacterized protein
chr4_-_5894777 12.09 ENST00000324989.7
CRMP1
collapsin response mediator protein 1
chr20_+_1246908 11.90 ENST00000381873.3
ENST00000381867.1
SNPH
syntaphilin
chr1_+_160175117 11.70 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr15_+_75287861 11.44 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
SCAMP5
secretory carrier membrane protein 5
chr15_-_73925651 11.18 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN
neuroplastin
chr11_-_18656028 10.93 ENST00000336349.5
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr7_-_124405681 10.78 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr10_-_62149433 10.62 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_102268628 9.94 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr5_+_140306478 9.85 ENST00000253807.2
PCDHAC1
protocadherin alpha subfamily C, 1
chr5_+_140810132 9.72 ENST00000252085.3
PCDHGA12
protocadherin gamma subfamily A, 12
chr5_+_140220769 9.72 ENST00000531613.1
ENST00000378123.3
PCDHA8
protocadherin alpha 8
chr1_+_50574585 9.57 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chrX_+_135067576 9.54 ENST00000370701.1
ENST00000370698.3
ENST00000370695.4
SLC9A6
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
chr16_+_66914264 9.49 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr5_+_140767452 9.48 ENST00000519479.1
PCDHGB4
protocadherin gamma subfamily B, 4
chr5_+_140718396 9.18 ENST00000394576.2
PCDHGA2
protocadherin gamma subfamily A, 2
chr21_-_27542972 9.15 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
APP
amyloid beta (A4) precursor protein
chr14_+_85996471 9.15 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr11_+_121322832 9.01 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr5_+_140227048 8.93 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr20_+_9494987 8.89 ENST00000427562.2
ENST00000246070.2
LAMP5
lysosomal-associated membrane protein family, member 5
chr13_-_36705425 8.84 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
DCLK1
doublecortin-like kinase 1
chr5_+_140248518 8.59 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr5_+_140213815 8.39 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr5_+_140254884 8.31 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr5_+_112043186 8.16 ENST00000509732.1
ENST00000457016.1
ENST00000507379.1
APC
adenomatous polyposis coli
chr18_-_53255766 7.87 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr6_+_44238203 7.86 ENST00000451188.2
TMEM151B
transmembrane protein 151B
chr13_-_110438914 7.41 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr5_+_140345820 7.35 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr4_-_90758227 7.28 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr19_+_18794470 7.13 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr12_-_42538657 6.73 ENST00000398675.3
GXYLT1
glucoside xylosyltransferase 1
chr11_-_73309228 6.48 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr20_+_54933971 6.47 ENST00000371384.3
ENST00000437418.1
FAM210B
family with sequence similarity 210, member B
chr17_-_41856305 6.34 ENST00000397937.2
ENST00000226004.3
DUSP3
dual specificity phosphatase 3
chr12_+_4918342 6.27 ENST00000280684.3
ENST00000433855.1
KCNA6
potassium voltage-gated channel, shaker-related subfamily, member 6
chr10_+_180987 6.26 ENST00000381591.1
ZMYND11
zinc finger, MYND-type containing 11
chr12_+_111471828 6.15 ENST00000261726.6
CUX2
cut-like homeobox 2
chr16_+_27561449 5.93 ENST00000261588.4
KIAA0556
KIAA0556
chr11_-_113746277 5.85 ENST00000003302.4
ENST00000545540.1
USP28
ubiquitin specific peptidase 28
chr5_+_140792614 5.67 ENST00000398610.2
PCDHGA10
protocadherin gamma subfamily A, 10
chr5_+_67511524 5.55 ENST00000521381.1
ENST00000521657.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_+_140723601 5.43 ENST00000253812.6
PCDHGA3
protocadherin gamma subfamily A, 3
chrX_-_47479246 5.42 ENST00000295987.7
ENST00000340666.4
SYN1
synapsin I
chr20_+_8112824 5.37 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chr14_+_35515598 5.31 ENST00000280987.4
FAM177A1
family with sequence similarity 177, member A1
chr5_+_139493665 5.29 ENST00000331327.3
PURA
purine-rich element binding protein A
chr14_-_77843390 5.26 ENST00000216468.7
TMED8
transmembrane emp24 protein transport domain containing 8
chr5_+_140165876 5.26 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr20_-_48099182 5.24 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr1_-_95392635 5.21 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr7_+_69064300 5.19 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr10_-_75634260 5.11 ENST00000372765.1
ENST00000351293.3
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chrX_-_33146477 5.09 ENST00000378677.2
DMD
dystrophin
chr20_-_47894569 4.83 ENST00000371744.1
ENST00000371752.1
ENST00000396105.1
ZNFX1
zinc finger, NFX1-type containing 1
chr5_+_140782351 4.83 ENST00000573521.1
PCDHGA9
protocadherin gamma subfamily A, 9
chr1_+_159141397 4.80 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
CADM3
cell adhesion molecule 3
chr17_-_33416231 4.71 ENST00000584655.1
ENST00000447669.2
ENST00000315249.7
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr13_-_53422640 4.63 ENST00000338862.4
ENST00000377942.3
PCDH8
protocadherin 8
chr16_+_8768422 4.59 ENST00000268251.8
ENST00000564714.1
ABAT
4-aminobutyrate aminotransferase
chr2_-_131850951 4.59 ENST00000409185.1
ENST00000389915.3
FAM168B
family with sequence similarity 168, member B
chr22_+_29469012 4.50 ENST00000400335.4
ENST00000400338.2
KREMEN1
kringle containing transmembrane protein 1
chrX_+_44732757 4.49 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A
lysine (K)-specific demethylase 6A
chr2_-_222436988 4.40 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPHA4
EPH receptor A4
chr4_+_72204755 4.33 ENST00000512686.1
ENST00000340595.3
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr2_-_37193606 4.25 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr15_-_52861394 4.18 ENST00000563277.1
ENST00000566423.1
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr2_-_47798044 4.14 ENST00000327876.4
KCNK12
potassium channel, subfamily K, member 12
chr15_-_42840961 4.13 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
LRRC57
leucine rich repeat containing 57
chr2_-_202316260 4.10 ENST00000332624.3
TRAK2
trafficking protein, kinesin binding 2
chr12_-_54673871 4.01 ENST00000209875.4
CBX5
chromobox homolog 5
chrX_-_18372792 3.95 ENST00000251900.4
SCML2
sex comb on midleg-like 2 (Drosophila)
chr5_+_156693091 3.82 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr2_+_207308220 3.77 ENST00000264377.3
ADAM23
ADAM metallopeptidase domain 23
chr5_+_140855495 3.77 ENST00000308177.3
PCDHGC3
protocadherin gamma subfamily C, 3
chr17_-_31620006 3.66 ENST00000225823.2
ASIC2
acid-sensing (proton-gated) ion channel 2
chr9_+_125703282 3.63 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chr5_-_137090028 3.62 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr8_+_79578282 3.59 ENST00000263849.4
ZC2HC1A
zinc finger, C2HC-type containing 1A
chr1_+_95582881 3.52 ENST00000370203.4
ENST00000456991.1
TMEM56
transmembrane protein 56
chr10_-_119806085 3.43 ENST00000355624.3
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr9_-_23821273 3.40 ENST00000380110.4
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr12_-_49110613 3.39 ENST00000261900.3
CCNT1
cyclin T1
chr5_+_140186647 3.39 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chr9_-_14314066 3.35 ENST00000397575.3
NFIB
nuclear factor I/B
chr5_+_140261703 3.33 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr4_-_39640700 3.30 ENST00000295958.5
SMIM14
small integral membrane protein 14
chr7_+_43152191 3.30 ENST00000395891.2
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr1_+_171810606 3.28 ENST00000358155.4
ENST00000367733.2
ENST00000355305.5
ENST00000367731.1
DNM3
dynamin 3
chr6_+_116601265 3.24 ENST00000452085.3
DSE
dermatan sulfate epimerase
chr12_+_113659234 3.22 ENST00000551096.1
ENST00000551099.1
ENST00000335509.6
ENST00000552897.1
ENST00000550785.1
ENST00000549279.1
TPCN1
two pore segment channel 1
chr12_-_122018859 3.19 ENST00000536437.1
ENST00000377071.4
ENST00000538046.2
KDM2B
lysine (K)-specific demethylase 2B
chr7_+_138916231 3.19 ENST00000473989.3
ENST00000288561.8
UBN2
ubinuclein 2
chr3_-_123304017 3.18 ENST00000383657.5
PTPLB
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
chr10_+_80828774 3.14 ENST00000334512.5
ZMIZ1
zinc finger, MIZ-type containing 1
chr2_+_24163281 3.13 ENST00000309033.4
UBXN2A
UBX domain protein 2A
chr12_+_55413721 3.10 ENST00000242994.3
NEUROD4
neuronal differentiation 4
chr8_+_107670064 3.09 ENST00000312046.6
OXR1
oxidation resistance 1
chr6_+_41040678 3.08 ENST00000341376.6
ENST00000353205.5
NFYA
nuclear transcription factor Y, alpha
chrX_+_10124977 3.00 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr4_+_2845547 2.98 ENST00000264758.7
ENST00000446856.1
ENST00000398125.1
ADD1
adducin 1 (alpha)
chr11_+_14665263 2.97 ENST00000282096.4
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr3_-_114790179 2.91 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr22_-_39151463 2.91 ENST00000405510.1
ENST00000433561.1
SUN2
Sad1 and UNC84 domain containing 2
chr8_-_93115445 2.91 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_4535025 2.90 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr15_-_30114622 2.82 ENST00000495972.2
ENST00000346128.6
TJP1
tight junction protein 1
chr15_-_78423886 2.76 ENST00000258930.3
CIB2
calcium and integrin binding family member 2
chr2_-_166060571 2.73 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr19_-_1174226 2.73 ENST00000587024.1
ENST00000361757.3
SBNO2
strawberry notch homolog 2 (Drosophila)
chr5_-_179780312 2.70 ENST00000253778.8
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr10_-_124768300 2.68 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr2_+_26915584 2.67 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr4_+_89513574 2.63 ENST00000402738.1
ENST00000431413.1
ENST00000422770.1
ENST00000407637.1
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr1_-_244013384 2.62 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr16_-_17564738 2.61 ENST00000261381.6
XYLT1
xylosyltransferase I
chr11_+_129939779 2.60 ENST00000533195.1
ENST00000533713.1
ENST00000528499.1
ENST00000539648.1
ENST00000263574.5
APLP2
amyloid beta (A4) precursor-like protein 2
chr15_+_33603147 2.58 ENST00000415757.3
ENST00000389232.4
RYR3
ryanodine receptor 3
chr4_-_42659102 2.58 ENST00000264449.10
ENST00000510289.1
ENST00000381668.5
ATP8A1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr5_+_140710061 2.56 ENST00000517417.1
ENST00000378105.3
PCDHGA1
protocadherin gamma subfamily A, 1
chr6_-_90529418 2.54 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1
MDN1, midasin homolog (yeast)
chr2_+_27070964 2.51 ENST00000288699.6
DPYSL5
dihydropyrimidinase-like 5
chr5_+_172483347 2.50 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF
CREB3 regulatory factor
chr3_-_18466787 2.47 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr9_-_130742792 2.46 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr1_+_155051305 2.46 ENST00000368408.3
EFNA3
ephrin-A3
chr8_+_1449532 2.43 ENST00000421627.2
DLGAP2
discs, large (Drosophila) homolog-associated protein 2
chr14_-_53417732 2.43 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2
fermitin family member 2
chr1_+_203595903 2.41 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr2_-_206950781 2.34 ENST00000403263.1
INO80D
INO80 complex subunit D
chr8_-_116681221 2.32 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr7_-_138666053 2.32 ENST00000440172.1
ENST00000422774.1
KIAA1549
KIAA1549
chr12_+_5019061 2.26 ENST00000382545.3
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr7_-_71801980 2.26 ENST00000329008.5
CALN1
calneuron 1
chr21_+_37692481 2.20 ENST00000400485.1
MORC3
MORC family CW-type zinc finger 3
chr2_-_182545603 2.19 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr9_-_77567743 2.18 ENST00000376854.5
C9orf40
chromosome 9 open reading frame 40
chr1_-_146644122 2.14 ENST00000254101.3
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr13_+_113951532 2.10 ENST00000332556.4
LAMP1
lysosomal-associated membrane protein 1
chr5_+_149109825 2.09 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr1_+_41249539 2.08 ENST00000347132.5
ENST00000509682.2
KCNQ4
potassium voltage-gated channel, KQT-like subfamily, member 4
chr14_-_91526922 2.04 ENST00000418736.2
ENST00000261991.3
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr17_-_4046257 2.03 ENST00000381638.2
ZZEF1
zinc finger, ZZ-type with EF-hand domain 1
chr21_-_43346790 1.99 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr21_-_38362497 1.99 ENST00000427746.1
ENST00000336648.4
HLCS
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr2_-_152955537 1.95 ENST00000201943.5
ENST00000539935.1
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr4_-_170924888 1.94 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr7_-_100076873 1.89 ENST00000300181.2
TSC22D4
TSC22 domain family, member 4
chr3_+_128444965 1.88 ENST00000265062.3
RAB7A
RAB7A, member RAS oncogene family
chr20_+_48599506 1.88 ENST00000244050.2
SNAI1
snail family zinc finger 1
chr8_-_74884511 1.87 ENST00000518127.1
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr8_+_37654424 1.87 ENST00000315215.7
GPR124
G protein-coupled receptor 124
chr6_+_101846664 1.87 ENST00000421544.1
ENST00000413795.1
ENST00000369138.1
ENST00000358361.3
GRIK2
glutamate receptor, ionotropic, kainate 2
chr17_+_16593539 1.87 ENST00000340621.5
ENST00000399273.1
ENST00000443444.2
ENST00000360524.8
ENST00000456009.1
CCDC144A
coiled-coil domain containing 144A
chr2_+_148602058 1.87 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
ACVR2A
activin A receptor, type IIA
chr6_+_170102210 1.86 ENST00000439249.1
ENST00000332290.2
C6orf120
chromosome 6 open reading frame 120
chr11_+_118401706 1.80 ENST00000411589.2
ENST00000442938.2
ENST00000359862.4
TMEM25
transmembrane protein 25
chr2_+_54683419 1.78 ENST00000356805.4
SPTBN1
spectrin, beta, non-erythrocytic 1
chr10_+_86088381 1.74 ENST00000224756.8
ENST00000372088.2
CCSER2
coiled-coil serine-rich protein 2
chr2_-_172750733 1.73 ENST00000392592.4
ENST00000422440.2
SLC25A12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr13_-_111567353 1.70 ENST00000310847.4
ENST00000267339.2
ENST00000375758.5
ANKRD10
ankyrin repeat domain 10
chr6_-_84140757 1.68 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr5_-_59189545 1.66 ENST00000340635.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_178790057 1.66 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr10_+_64564469 1.60 ENST00000373783.1
ADO
2-aminoethanethiol (cysteamine) dioxygenase
chr2_+_5832799 1.59 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr7_-_6312206 1.57 ENST00000350796.3
CYTH3
cytohesin 3
chr6_-_34664612 1.53 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr2_-_11484710 1.52 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr12_-_85306594 1.51 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr19_+_36208877 1.49 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
KMT2B
Histone-lysine N-methyltransferase 2B
chr1_+_202317815 1.49 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr18_+_13218769 1.49 ENST00000399848.3
ENST00000361205.4
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr13_-_79979919 1.46 ENST00000267229.7
RBM26
RNA binding motif protein 26
chr11_+_33278811 1.44 ENST00000303296.4
ENST00000379016.3
HIPK3
homeodomain interacting protein kinase 3
chr2_+_74881355 1.43 ENST00000357877.2
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr1_+_213123915 1.40 ENST00000366968.4
ENST00000490792.1
VASH2
vasohibin 2
chr1_-_57889687 1.38 ENST00000371236.2
ENST00000371230.1
DAB1
Dab, reelin signal transducer, homolog 1 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of UGCAUAG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.0 24.0 GO:0033693 neurofilament bundle assembly(GO:0033693)
6.5 32.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
5.7 22.9 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
5.2 15.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
4.0 12.1 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
3.7 11.2 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
3.3 9.9 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
3.0 9.0 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
2.7 10.6 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
2.4 7.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
1.8 9.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
1.8 299.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.8 5.4 GO:0090427 activation of meiosis(GO:0090427)
1.7 12.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
1.5 15.4 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
1.5 4.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
1.5 4.4 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
1.5 7.3 GO:0051622 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
1.4 4.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
1.3 5.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
1.3 5.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.2 8.7 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
1.2 7.4 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
1.2 4.7 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
1.1 3.2 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
1.0 4.8 GO:0071286 cellular response to magnesium ion(GO:0071286)
1.0 9.5 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.9 2.8 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.9 8.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.9 5.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.8 2.5 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.8 2.4 GO:2000282 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.8 11.7 GO:0046325 negative regulation of glucose import(GO:0046325)
0.7 8.8 GO:0016081 synaptic vesicle docking(GO:0016081)
0.7 2.9 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.7 2.0 GO:0070781 response to biotin(GO:0070781)
0.6 2.6 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.6 8.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.6 1.9 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.6 6.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.6 1.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.6 10.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.5 5.9 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.5 1.6 GO:0061386 closure of optic fissure(GO:0061386)
0.5 5.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.5 2.1 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.5 3.7 GO:0050915 sensory perception of sour taste(GO:0050915)
0.5 3.1 GO:0007296 vitellogenesis(GO:0007296)
0.5 12.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.5 2.9 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.5 3.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.5 1.9 GO:0042713 sperm ejaculation(GO:0042713)
0.5 1.4 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.5 2.7 GO:0071105 response to interleukin-11(GO:0071105)
0.4 1.8 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.4 1.3 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.4 3.0 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.4 2.0 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.4 1.9 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.4 6.8 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.4 1.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.3 3.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3 0.7 GO:1990036 calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.3 1.5 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.3 1.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.3 0.9 GO:1904693 serotonergic neuron axon guidance(GO:0036515) negative regulation of mitotic cell cycle, embryonic(GO:0045976) midbrain morphogenesis(GO:1904693)
0.3 3.0 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.3 1.8 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 6.1 GO:0007614 short-term memory(GO:0007614)
0.3 1.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.3 0.8 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 1.3 GO:2000301 regulation of intracellular transport of viral material(GO:1901252) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 2.7 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.2 5.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.2 1.9 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 6.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 2.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 4.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.2 13.6 GO:0035418 protein localization to synapse(GO:0035418)
0.2 6.3 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.2 0.6 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 1.4 GO:0008360 regulation of cell shape(GO:0008360)
0.2 1.0 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 5.4 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.2 1.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 0.9 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 2.5 GO:0060004 reflex(GO:0060004)
0.2 2.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 0.6 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 2.8 GO:0071318 cellular response to ATP(GO:0071318)
0.2 0.6 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2 5.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 0.5 GO:1901896 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 1.0 GO:0042426 choline catabolic process(GO:0042426)
0.1 3.6 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 1.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 6.5 GO:0006284 base-excision repair(GO:0006284)
0.1 1.6 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 2.1 GO:0006853 carnitine shuttle(GO:0006853)
0.1 1.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 2.1 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 1.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 1.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 3.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 1.0 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 2.4 GO:0033622 integrin activation(GO:0033622)
0.1 0.6 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 1.2 GO:0007346 regulation of mitotic cell cycle(GO:0007346)
0.1 0.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 1.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 2.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 4.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.3 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.4 GO:1900125 regulation of hyaluronan biosynthetic process(GO:1900125)
0.1 5.9 GO:0034644 cellular response to UV(GO:0034644)
0.1 3.4 GO:0003091 renal water homeostasis(GO:0003091)
0.1 0.3 GO:0021997 response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.1 0.3 GO:0072144 renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.1 2.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.9 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.1 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.7 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1 0.6 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 2.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.3 GO:0051643 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) secretory granule localization(GO:0032252) endoplasmic reticulum localization(GO:0051643)
0.1 2.9 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 1.4 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.1 1.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 2.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 3.1 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 3.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 2.3 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 2.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 1.9 GO:0007626 locomotory behavior(GO:0007626)
0.0 0.3 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.8 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 1.0 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.8 GO:0009994 oocyte differentiation(GO:0009994)
0.0 0.7 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 1.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.0 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.6 GO:0014002 astrocyte development(GO:0014002)
0.0 0.6 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.6 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 2.1 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.2 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 2.3 GO:0006310 DNA recombination(GO:0006310)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
10.3 41.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
3.1 15.7 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.9 9.5 GO:0044308 axonal spine(GO:0044308)
1.8 26.4 GO:0005883 neurofilament(GO:0005883)
1.4 12.8 GO:0005955 calcineurin complex(GO:0005955)
1.4 5.6 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
1.3 8.9 GO:0032584 growth cone membrane(GO:0032584)
1.2 18.2 GO:0005641 nuclear envelope lumen(GO:0005641)
1.1 4.6 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.9 11.2 GO:0060077 inhibitory synapse(GO:0060077)
0.7 8.2 GO:1990909 catenin complex(GO:0016342) Wnt signalosome(GO:1990909)
0.7 3.3 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.6 4.5 GO:0032437 cuticular plate(GO:0032437)
0.6 11.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.6 3.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.6 5.1 GO:0016013 syntrophin complex(GO:0016013)
0.5 4.0 GO:0097208 alveolar lamellar body(GO:0097208)
0.5 1.9 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.4 1.3 GO:0019034 viral replication complex(GO:0019034)
0.4 1.2 GO:0043291 RAVE complex(GO:0043291)
0.4 18.2 GO:0048786 presynaptic active zone(GO:0048786)
0.4 2.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.4 5.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 3.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 9.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 2.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 3.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 4.7 GO:0044295 axonal growth cone(GO:0044295)
0.2 2.9 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 15.6 GO:0042734 presynaptic membrane(GO:0042734)
0.2 4.0 GO:0010369 chromocenter(GO:0010369)
0.2 11.4 GO:0031201 SNARE complex(GO:0031201)
0.2 5.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 3.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 2.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 6.3 GO:0001772 immunological synapse(GO:0001772)
0.2 8.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 1.7 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 4.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 2.0 GO:0005652 nuclear lamina(GO:0005652)
0.2 327.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.2 20.6 GO:0030426 growth cone(GO:0030426)
0.2 0.5 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 2.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 4.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.6 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 7.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.0 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 2.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.6 GO:0033391 chromatoid body(GO:0033391)
0.1 3.1 GO:0005801 cis-Golgi network(GO:0005801)
0.1 5.9 GO:0043235 receptor complex(GO:0043235)
0.1 2.1 GO:0016592 mediator complex(GO:0016592)
0.1 1.1 GO:0044216 host(GO:0018995) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 11.9 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 2.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 4.6 GO:0030496 midbody(GO:0030496)
0.0 1.6 GO:0001726 ruffle(GO:0001726)
0.0 0.7 GO:0043195 terminal bouton(GO:0043195)
0.0 1.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.5 GO:0031672 A band(GO:0031672)
0.0 7.1 GO:0043025 neuronal cell body(GO:0043025)
0.0 2.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 3.2 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.0 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 15.7 GO:0030348 syntaxin-3 binding(GO:0030348)
2.8 11.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
2.0 53.2 GO:0017075 syntaxin-1 binding(GO:0017075)
1.8 5.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.7 10.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.5 7.7 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
1.5 4.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.5 7.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
1.1 4.6 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
1.1 5.6 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
1.1 3.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
1.1 15.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
1.0 10.9 GO:0001042 RNA polymerase I core binding(GO:0001042)
1.0 3.0 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
1.0 9.5 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.9 9.2 GO:0051425 PTB domain binding(GO:0051425)
0.8 2.4 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.8 3.0 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.7 3.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.7 2.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.7 6.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.6 7.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.6 12.1 GO:0031005 filamin binding(GO:0031005)
0.6 9.2 GO:0045499 chemorepellent activity(GO:0045499)
0.6 9.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.5 5.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.5 13.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 7.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 3.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.4 8.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.4 3.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.4 8.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.4 6.3 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.4 4.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.4 28.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.4 13.1 GO:0017091 AU-rich element binding(GO:0017091)
0.3 288.5 GO:0005509 calcium ion binding(GO:0005509)
0.3 8.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.3 1.9 GO:0098821 BMP receptor activity(GO:0098821)
0.3 1.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.3 2.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.3 14.3 GO:0030507 spectrin binding(GO:0030507)
0.3 3.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.3 1.7 GO:0008948 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.3 3.2 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.3 1.3 GO:0034046 poly(G) binding(GO:0034046)
0.3 1.0 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 1.2 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.2 4.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 10.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 5.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 1.3 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 0.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 2.8 GO:0043495 protein anchor(GO:0043495)
0.2 2.0 GO:0009374 biotin binding(GO:0009374)
0.2 4.1 GO:0050811 GABA receptor binding(GO:0050811)
0.2 25.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 2.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 2.7 GO:0008483 transaminase activity(GO:0008483)
0.1 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 20.8 GO:0051015 actin filament binding(GO:0051015)
0.1 0.6 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 4.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 2.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.4 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 4.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 6.9 GO:0002039 p53 binding(GO:0002039)
0.1 1.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 3.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.3 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 7.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 1.1 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.7 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.6 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 3.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 2.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.2 GO:0003707 steroid hormone receptor activity(GO:0003707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 4.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.3 19.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.3 12.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.3 8.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 1.9 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.3 1.9 PID ALK1 PATHWAY ALK1 signaling events
0.2 8.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 11.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 5.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.6 ST GAQ PATHWAY G alpha q Pathway
0.1 7.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 6.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 1.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 6.0 PID TNF PATHWAY TNF receptor signaling pathway
0.1 1.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 9.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 2.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 9.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 7.9 PID P73PATHWAY p73 transcription factor network
0.0 1.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 3.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 3.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 62.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.6 10.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5 14.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.5 8.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.5 5.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5 9.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.4 6.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.4 2.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 11.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 5.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.3 12.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.3 5.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 11.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 4.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 3.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 1.5 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.2 2.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.2 11.2 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.2 2.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 2.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 3.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 7.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 5.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 2.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 3.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 7.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 9.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 5.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 3.4 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 1.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 2.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.1 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 2.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway