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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for UGCAUUG

Z-value: 0.41

Motif logo

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miRNA associated with seed UGCAUUG

NamemiRBASE accession
hsa-miR-33a-5p
MIMAT0000091
hsa-miR-33b-5p
MIMAT0003301

Activity profile of UGCAUUG motif

Sorted Z-values of UGCAUUG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_48920960 1.93 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
chr1_-_20812690 1.79 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr3_-_149688896 1.27 ENST00000239940.7
PFN2
profilin 2
chr20_+_44657845 1.25 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr10_+_54074033 1.22 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr17_+_44668035 1.20 ENST00000398238.4
ENST00000225282.8
NSF
N-ethylmaleimide-sensitive factor
chr15_+_52311398 0.98 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr5_+_140227048 0.89 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr2_-_2334888 0.88 ENST00000428368.2
ENST00000399161.2
MYT1L
myelin transcription factor 1-like
chr2_-_183903133 0.88 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr16_+_56672571 0.86 ENST00000290705.8
MT1A
metallothionein 1A
chr1_+_110527308 0.80 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr12_+_66217911 0.77 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr5_+_140220769 0.77 ENST00000531613.1
ENST00000378123.3
PCDHA8
protocadherin alpha 8
chr5_+_140345820 0.74 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr20_+_11871371 0.74 ENST00000254977.3
BTBD3
BTB (POZ) domain containing 3
chr1_+_10271674 0.73 ENST00000377086.1
KIF1B
kinesin family member 1B
chr7_+_35840542 0.72 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7
septin 7
chr2_+_74425689 0.72 ENST00000394053.2
ENST00000409804.1
ENST00000264090.4
ENST00000394050.3
ENST00000409601.1
MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr5_+_140306478 0.70 ENST00000253807.2
PCDHAC1
protocadherin alpha subfamily C, 1
chr9_+_112810878 0.70 ENST00000434623.2
ENST00000374525.1
AKAP2
A kinase (PRKA) anchor protein 2
chr18_-_21166841 0.69 ENST00000269228.5
NPC1
Niemann-Pick disease, type C1
chr5_+_140248518 0.67 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr5_+_65222299 0.67 ENST00000284037.5
ERBB2IP
erbb2 interacting protein
chr7_-_124405681 0.66 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr9_+_112542572 0.64 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr1_-_109584608 0.62 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47
WD repeat domain 47
chr2_-_50574856 0.55 ENST00000342183.5
NRXN1
neurexin 1
chr19_+_41725088 0.53 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr5_+_140213815 0.51 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr2_-_47168906 0.51 ENST00000444761.2
ENST00000409147.1
MCFD2
multiple coagulation factor deficiency 2
chr5_+_140254884 0.50 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr12_-_56694142 0.49 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
CS
citrate synthase
chr5_+_74632993 0.49 ENST00000287936.4
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr6_+_69345166 0.49 ENST00000370598.1
BAI3
brain-specific angiogenesis inhibitor 3
chr10_+_63661053 0.44 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chrX_+_47077632 0.44 ENST00000457458.2
CDK16
cyclin-dependent kinase 16
chr10_-_119134918 0.43 ENST00000334464.5
PDZD8
PDZ domain containing 8
chr8_+_104831472 0.42 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr14_+_57735614 0.42 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr4_+_140222609 0.41 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr17_-_1083078 0.40 ENST00000574266.1
ENST00000302538.5
ABR
active BCR-related
chr15_+_85523671 0.39 ENST00000310298.4
ENST00000557957.1
PDE8A
phosphodiesterase 8A
chr5_+_140165876 0.37 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr8_-_53322303 0.36 ENST00000276480.7
ST18
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
chr2_-_200322723 0.36 ENST00000417098.1
SATB2
SATB homeobox 2
chr8_+_64081118 0.35 ENST00000539294.1
YTHDF3
YTH domain family, member 3
chr8_+_110552337 0.35 ENST00000337573.5
EBAG9
estrogen receptor binding site associated, antigen, 9
chr2_-_9143786 0.34 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr14_+_103243813 0.34 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3
TNF receptor-associated factor 3
chr11_+_22359562 0.34 ENST00000263160.3
SLC17A6
solute carrier family 17 (vesicular glutamate transporter), member 6
chr3_+_150321068 0.33 ENST00000471696.1
ENST00000477889.1
ENST00000485923.1
SELT
Selenoprotein T
chr5_+_86564739 0.33 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr21_-_16437255 0.33 ENST00000400199.1
ENST00000400202.1
NRIP1
nuclear receptor interacting protein 1
chr5_-_133512683 0.32 ENST00000353411.6
SKP1
S-phase kinase-associated protein 1
chr10_+_96162242 0.31 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr13_-_103053946 0.31 ENST00000376131.4
FGF14
fibroblast growth factor 14
chr16_+_67880574 0.31 ENST00000219169.4
NUTF2
nuclear transport factor 2
chr5_+_82767284 0.29 ENST00000265077.3
VCAN
versican
chr5_-_108745689 0.29 ENST00000361189.2
PJA2
praja ring finger 2, E3 ubiquitin protein ligase
chr3_-_192445289 0.29 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12
fibroblast growth factor 12
chr10_-_62149433 0.29 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr11_-_70507901 0.28 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr6_-_52441713 0.27 ENST00000182527.3
TRAM2
translocation associated membrane protein 2
chr6_+_158733692 0.27 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr20_-_32700075 0.27 ENST00000374980.2
EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr10_-_75634260 0.26 ENST00000372765.1
ENST00000351293.3
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr14_+_55034599 0.26 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr11_-_790060 0.26 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1
chr7_-_83824169 0.25 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_+_57984965 0.25 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr5_+_140186647 0.23 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chr2_-_26101374 0.23 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr10_+_80828774 0.22 ENST00000334512.5
ZMIZ1
zinc finger, MIZ-type containing 1
chr5_+_140261703 0.22 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr2_-_166930131 0.22 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr3_+_150126101 0.22 ENST00000361875.3
ENST00000361136.2
TSC22D2
TSC22 domain family, member 2
chr2_-_86564776 0.22 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr4_-_53525406 0.21 ENST00000451218.2
ENST00000441222.3
USP46
ubiquitin specific peptidase 46
chr19_-_2015699 0.21 ENST00000255608.4
BTBD2
BTB (POZ) domain containing 2
chr3_-_182698381 0.21 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr3_-_164913777 0.21 ENST00000475390.1
SLITRK3
SLIT and NTRK-like family, member 3
chr9_-_107690420 0.20 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr6_-_86352642 0.20 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr8_+_98656336 0.18 ENST00000336273.3
MTDH
metadherin
chr16_-_69419871 0.18 ENST00000603068.1
ENST00000254942.3
ENST00000567296.2
TERF2
telomeric repeat binding factor 2
chr17_-_1359443 0.17 ENST00000574295.1
ENST00000398970.5
ENST00000300574.2
CRK
v-crk avian sarcoma virus CT10 oncogene homolog
chr3_-_160283348 0.17 ENST00000334256.4
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr12_-_104532062 0.17 ENST00000240055.3
NFYB
nuclear transcription factor Y, beta
chr8_+_1449532 0.16 ENST00000421627.2
DLGAP2
discs, large (Drosophila) homolog-associated protein 2
chr17_+_5031687 0.16 ENST00000250066.6
ENST00000304328.5
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr1_+_182992545 0.16 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr10_+_64564469 0.16 ENST00000373783.1
ADO
2-aminoethanethiol (cysteamine) dioxygenase
chr4_-_79860506 0.16 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
PAQR3
progestin and adipoQ receptor family member III
chr9_+_34990219 0.16 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr19_+_34919257 0.15 ENST00000246548.4
ENST00000590048.2
UBA2
ubiquitin-like modifier activating enzyme 2
chr4_-_85887503 0.15 ENST00000509172.1
ENST00000322366.6
ENST00000295888.4
ENST00000502713.1
WDFY3
WD repeat and FYVE domain containing 3
chr8_+_77593448 0.15 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr15_-_68498376 0.15 ENST00000540479.1
ENST00000395465.3
CALML4
calmodulin-like 4
chr7_+_29234028 0.15 ENST00000222792.6
CHN2
chimerin 2
chr1_-_160254913 0.14 ENST00000440949.3
ENST00000368072.5
ENST00000608310.1
ENST00000556710.1
PEX19
DCAF8
DCAF8
peroxisomal biogenesis factor 19
DDB1 and CUL4 associated factor 8
DDB1- and CUL4-associated factor 8
chr7_-_26578407 0.14 ENST00000242109.3
KIAA0087
KIAA0087
chr10_-_98346801 0.13 ENST00000371142.4
TM9SF3
transmembrane 9 superfamily member 3
chr4_-_46996424 0.13 ENST00000264318.3
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr2_+_46926048 0.13 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr5_-_168006591 0.13 ENST00000239231.6
PANK3
pantothenate kinase 3
chr1_+_101003687 0.12 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr7_-_126892303 0.11 ENST00000358373.3
GRM8
glutamate receptor, metabotropic 8
chr22_-_42017021 0.11 ENST00000263256.6
DESI1
desumoylating isopeptidase 1
chr1_+_145611010 0.11 ENST00000369291.5
RNF115
ring finger protein 115
chr7_-_19157248 0.10 ENST00000242261.5
TWIST1
twist family bHLH transcription factor 1
chr10_+_101088836 0.10 ENST00000356713.4
CNNM1
cyclin M1
chr5_-_59189545 0.09 ENST00000340635.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr18_+_55018044 0.09 ENST00000324000.3
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr19_+_1752372 0.09 ENST00000382349.4
ONECUT3
one cut homeobox 3
chr4_+_144434584 0.09 ENST00000283131.3
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr18_+_13218769 0.09 ENST00000399848.3
ENST00000361205.4
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr17_-_58603568 0.08 ENST00000083182.3
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr6_+_101846664 0.08 ENST00000421544.1
ENST00000413795.1
ENST00000369138.1
ENST00000358361.3
GRIK2
glutamate receptor, ionotropic, kainate 2
chr15_+_85359911 0.08 ENST00000258888.5
ALPK3
alpha-kinase 3
chr16_-_4987065 0.07 ENST00000590782.2
ENST00000345988.2
PPL
periplakin
chr5_+_134094461 0.07 ENST00000452510.2
ENST00000354283.4
DDX46
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr11_-_128737163 0.07 ENST00000324003.3
ENST00000392665.2
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr2_+_26467762 0.07 ENST00000317799.5
ENST00000405867.3
ENST00000537713.1
HADHB
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
chr2_-_222436988 0.06 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPHA4
EPH receptor A4
chr8_+_106330920 0.06 ENST00000407775.2
ZFPM2
zinc finger protein, FOG family member 2
chr5_+_153570285 0.06 ENST00000425427.2
ENST00000297107.6
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr2_-_122042770 0.06 ENST00000263707.5
TFCP2L1
transcription factor CP2-like 1
chr4_-_73434498 0.06 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr1_-_84464780 0.06 ENST00000260505.8
TTLL7
tubulin tyrosine ligase-like family, member 7
chr7_-_92463210 0.05 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr8_-_103425047 0.05 ENST00000520539.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr13_+_98086445 0.05 ENST00000245304.4
RAP2A
RAP2A, member of RAS oncogene family
chr1_-_46598284 0.05 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr9_-_124989804 0.04 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr1_+_181452678 0.04 ENST00000367570.1
ENST00000526775.1
ENST00000357570.5
ENST00000358338.5
ENST00000367567.4
CACNA1E
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr14_+_57046500 0.04 ENST00000261556.6
TMEM260
transmembrane protein 260
chr15_+_89631381 0.04 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr10_-_5855350 0.04 ENST00000456041.1
ENST00000380181.3
ENST00000418688.1
ENST00000380132.4
ENST00000609712.1
ENST00000380191.4
GDI2
GDP dissociation inhibitor 2
chr13_+_102104980 0.03 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr17_+_41177220 0.03 ENST00000587250.2
ENST00000544533.1
RND2
Rho family GTPase 2
chr10_+_76586348 0.03 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B
K(lysine) acetyltransferase 6B
chr17_+_8924837 0.03 ENST00000173229.2
NTN1
netrin 1
chr15_-_45815005 0.02 ENST00000261867.4
SLC30A4
solute carrier family 30 (zinc transporter), member 4
chr1_-_93257951 0.02 ENST00000543509.1
ENST00000370331.1
ENST00000540033.1
EVI5
ecotropic viral integration site 5
chr18_-_18691739 0.02 ENST00000399799.2
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr5_+_140201183 0.02 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5
protocadherin alpha 5
chr8_-_93115445 0.01 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_-_38657849 0.01 ENST00000254051.6
TNS4
tensin 4
chr10_+_75504105 0.01 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24C
SEC24 family member C
chr2_+_60983361 0.01 ENST00000238714.3
PAPOLG
poly(A) polymerase gamma
chr13_+_26828275 0.00 ENST00000381527.3
CDK8
cyclin-dependent kinase 8
chr17_+_61086917 0.00 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr16_-_53737795 0.00 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1L
RPGRIP1-like
chr15_-_42264702 0.00 ENST00000220325.4
EHD4
EH-domain containing 4
chr18_-_53255766 0.00 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4

Network of associatons between targets according to the STRING database.

First level regulatory network of UGCAUUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.3 1.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.3 0.8 GO:0031049 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.2 0.7 GO:1904647 response to rotenone(GO:1904647)
0.1 0.7 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 0.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.5 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 0.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.3 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1 0.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.9 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.7 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.1 0.2 GO:0031627 telomeric loop formation(GO:0031627) negative regulation of t-circle formation(GO:1904430)
0.1 0.3 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1 0.2 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.2 GO:0048880 sensory system development(GO:0048880)
0.0 0.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.4 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 1.2 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.3 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.3 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0002176 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 0.1 GO:2000275 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) regulation of oxidative phosphorylation uncoupler activity(GO:2000275) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:2001023 regulation of response to drug(GO:2001023)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 5.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.9 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.9 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.3 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0060013 righting reflex(GO:0060013)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.7 GO:0046653 tetrahydrofolate metabolic process(GO:0046653) folic acid metabolic process(GO:0046655)
0.0 0.4 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.2 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.3 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.4 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.3 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.3 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.4 GO:0016577 histone demethylation(GO:0016577)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.3 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.4 GO:0002076 osteoblast development(GO:0002076)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.7 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 0.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.4 GO:0031415 NatA complex(GO:0031415)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.0 2.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.0 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.5 GO:0033643 host cell part(GO:0033643)
0.0 0.4 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.6 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.3 0.8 GO:0035501 MH1 domain binding(GO:0035501)
0.2 0.7 GO:0004487 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 0.8 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.2 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 1.0 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 1.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.5 GO:0070402 NADPH binding(GO:0070402)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.3 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0098505 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.7 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.4 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.8 GO:0048365 Rac GTPase binding(GO:0048365)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling