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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for UUGGCAA

Z-value: 0.22

Motif logo

logo of

miRNA associated with seed UUGGCAA

NamemiRBASE accession
hsa-miR-182-5p
MIMAT0000259

Activity profile of UUGGCAA motif

Sorted Z-values of UUGGCAA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_171758344 5.62 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr2_-_151344172 5.32 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr11_-_115375107 5.00 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr7_-_105925558 4.84 ENST00000222553.3
NAMPT
nicotinamide phosphoribosyltransferase
chr11_+_114128522 4.61 ENST00000535401.1
NNMT
nicotinamide N-methyltransferase
chr12_-_109125285 4.33 ENST00000552871.1
ENST00000261401.3
CORO1C
coronin, actin binding protein, 1C
chr1_-_86043921 4.20 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_+_235860616 4.03 ENST00000392011.2
SH3BP4
SH3-domain binding protein 4
chr2_-_183903133 3.78 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr2_+_109204909 3.75 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr3_+_197476621 3.72 ENST00000241502.4
FYTTD1
forty-two-three domain containing 1
chr7_-_47621736 3.68 ENST00000311160.9
TNS3
tensin 3
chr5_+_86564739 3.68 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr5_-_137878887 3.65 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr3_-_134093395 3.54 ENST00000249883.5
AMOTL2
angiomotin like 2
chr1_+_7831323 3.34 ENST00000054666.6
VAMP3
vesicle-associated membrane protein 3
chr2_+_187350883 3.29 ENST00000337859.6
ZC3H15
zinc finger CCCH-type containing 15
chr3_-_182698381 3.25 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr19_-_48894762 3.24 ENST00000600980.1
ENST00000330720.2
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr10_-_16859361 3.22 ENST00000377921.3
RSU1
Ras suppressor protein 1
chr6_+_64281906 3.13 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr14_+_56046914 3.04 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1
kinectin 1 (kinesin receptor)
chr3_+_187930719 2.99 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_+_182992545 2.97 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr1_+_231664390 2.95 ENST00000366639.4
ENST00000413309.2
TSNAX
translin-associated factor X
chr10_-_119134918 2.92 ENST00000334464.5
PDZD8
PDZ domain containing 8
chr17_+_66508537 2.91 ENST00000392711.1
ENST00000585427.1
ENST00000589228.1
ENST00000536854.2
ENST00000588702.1
ENST00000589309.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr1_-_68962782 2.84 ENST00000456315.2
DEPDC1
DEP domain containing 1
chr5_+_71403061 2.82 ENST00000512974.1
ENST00000296755.7
MAP1B
microtubule-associated protein 1B
chr1_-_55352834 2.81 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chr1_+_165796753 2.81 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr3_+_61547585 2.80 ENST00000295874.10
ENST00000474889.1
PTPRG
protein tyrosine phosphatase, receptor type, G
chr7_+_35840542 2.74 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7
septin 7
chr2_+_46769798 2.71 ENST00000238738.4
RHOQ
ras homolog family member Q
chr21_-_15755446 2.70 ENST00000544452.1
ENST00000285667.3
HSPA13
heat shock protein 70kDa family, member 13
chr1_-_94703118 2.67 ENST00000260526.6
ENST00000370217.3
ARHGAP29
Rho GTPase activating protein 29
chr6_+_47445467 2.59 ENST00000359314.5
CD2AP
CD2-associated protein
chr7_+_94285637 2.55 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr1_-_85742773 2.45 ENST00000370580.1
BCL10
B-cell CLL/lymphoma 10
chr2_-_174830430 2.41 ENST00000310015.6
ENST00000455789.2
SP3
Sp3 transcription factor
chr1_-_211752073 2.40 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr6_+_17600576 2.40 ENST00000259963.3
FAM8A1
family with sequence similarity 8, member A1
chr3_+_87276407 2.36 ENST00000471660.1
ENST00000263780.4
ENST00000494980.1
CHMP2B
charged multivesicular body protein 2B
chr2_-_44588893 2.34 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
PREPL
prolyl endopeptidase-like
chr16_+_83841448 2.30 ENST00000433866.2
HSBP1
heat shock factor binding protein 1
chr11_+_111807863 2.28 ENST00000440460.2
DIXDC1
DIX domain containing 1
chr17_+_45727204 2.27 ENST00000290158.4
KPNB1
karyopherin (importin) beta 1
chr8_+_98656336 2.27 ENST00000336273.3
MTDH
metadherin
chr7_+_17338239 2.26 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chr21_-_34852304 2.23 ENST00000542230.2
TMEM50B
transmembrane protein 50B
chr5_-_133968529 2.23 ENST00000402673.2
SAR1B
SAR1 homolog B (S. cerevisiae)
chr6_-_169654139 2.21 ENST00000366787.3
THBS2
thrombospondin 2
chr12_+_104682496 2.19 ENST00000378070.4
TXNRD1
thioredoxin reductase 1
chr1_+_224544552 2.18 ENST00000465271.1
ENST00000366858.3
CNIH4
cornichon family AMPA receptor auxiliary protein 4
chrX_-_153151586 2.17 ENST00000370060.1
ENST00000370055.1
ENST00000420165.1
L1CAM
L1 cell adhesion molecule
chr1_+_193091080 2.16 ENST00000367435.3
CDC73
cell division cycle 73
chrX_+_146993449 2.13 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
FMR1
fragile X mental retardation 1
chr11_+_842808 2.10 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
TSPAN4
tetraspanin 4
chr1_+_110091189 2.10 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr12_+_72148614 2.06 ENST00000261263.3
RAB21
RAB21, member RAS oncogene family
chr4_-_102268628 2.04 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr21_+_42539701 1.97 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
BACE2
beta-site APP-cleaving enzyme 2
chr1_+_40723779 1.96 ENST00000372759.3
ZMPSTE24
zinc metallopeptidase STE24
chr1_-_95392635 1.95 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr10_+_75936444 1.95 ENST00000372734.3
ENST00000541550.1
ADK
adenosine kinase
chr9_+_110045537 1.94 ENST00000358015.3
RAD23B
RAD23 homolog B (S. cerevisiae)
chr2_-_47168906 1.92 ENST00000444761.2
ENST00000409147.1
MCFD2
multiple coagulation factor deficiency 2
chr10_+_75757863 1.90 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
VCL
vinculin
chr10_-_120840309 1.90 ENST00000369144.3
EIF3A
eukaryotic translation initiation factor 3, subunit A
chr1_-_109584608 1.88 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47
WD repeat domain 47
chr1_+_230202936 1.87 ENST00000366672.4
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr2_+_121010324 1.86 ENST00000272519.5
RALB
v-ral simian leukemia viral oncogene homolog B
chr12_+_124069070 1.85 ENST00000262225.3
ENST00000438031.2
TMED2
transmembrane emp24 domain trafficking protein 2
chr9_+_2621798 1.85 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr20_+_47662805 1.82 ENST00000262982.2
ENST00000542325.1
CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr1_-_20812690 1.81 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr6_+_71998506 1.81 ENST00000370435.4
OGFRL1
opioid growth factor receptor-like 1
chr5_-_9546180 1.79 ENST00000382496.5
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr13_-_50367057 1.78 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr3_-_15374033 1.77 ENST00000253688.5
ENST00000383791.3
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr10_-_62704005 1.75 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr2_-_38303218 1.74 ENST00000407341.1
ENST00000260630.3
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr9_+_137533615 1.74 ENST00000371817.3
COL5A1
collagen, type V, alpha 1
chr6_-_79787902 1.73 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr3_-_57583130 1.73 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr4_+_55095264 1.72 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr2_-_55237484 1.72 ENST00000394609.2
RTN4
reticulon 4
chr10_+_112679301 1.71 ENST00000265277.5
ENST00000369452.4
SHOC2
soc-2 suppressor of clear homolog (C. elegans)
chr4_+_41992489 1.68 ENST00000264451.7
SLC30A9
solute carrier family 30 (zinc transporter), member 9
chr10_+_93558069 1.68 ENST00000371627.4
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr5_-_179499086 1.68 ENST00000261947.4
RNF130
ring finger protein 130
chr3_+_179370517 1.68 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr8_-_103876965 1.66 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr20_+_56884752 1.65 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr6_-_109703663 1.65 ENST00000368961.5
CD164
CD164 molecule, sialomucin
chr18_-_18691739 1.64 ENST00000399799.2
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr20_+_361261 1.64 ENST00000217233.3
TRIB3
tribbles pseudokinase 3
chr4_+_169418195 1.64 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr2_-_216300784 1.62 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr3_+_180630090 1.62 ENST00000357559.4
ENST00000305586.7
FXR1
fragile X mental retardation, autosomal homolog 1
chr10_+_62538089 1.61 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chr6_+_56954867 1.60 ENST00000370708.4
ENST00000370702.1
ZNF451
zinc finger protein 451
chr20_-_50384864 1.57 ENST00000311637.5
ENST00000402822.1
ATP9A
ATPase, class II, type 9A
chr9_-_36276966 1.56 ENST00000543356.2
ENST00000396594.3
GNE
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr9_-_74980113 1.55 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr14_+_57735614 1.55 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr7_+_129710350 1.53 ENST00000335420.5
ENST00000463413.1
KLHDC10
kelch domain containing 10
chr4_-_129208940 1.52 ENST00000296425.5
PGRMC2
progesterone receptor membrane component 2
chr11_+_118477144 1.52 ENST00000361417.2
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr14_-_73925225 1.50 ENST00000356296.4
ENST00000355058.3
ENST00000359560.3
ENST00000557597.1
ENST00000554394.1
ENST00000555238.1
ENST00000535282.1
ENST00000555987.1
ENST00000555394.1
ENST00000554546.1
NUMB
numb homolog (Drosophila)
chr3_+_69812877 1.49 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr12_-_102513843 1.48 ENST00000551744.2
ENST00000552283.1
NUP37
nucleoporin 37kDa
chr4_+_39699664 1.47 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
UBE2K
ubiquitin-conjugating enzyme E2K
chr11_-_8680383 1.47 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr7_-_25164969 1.46 ENST00000305786.2
CYCS
cytochrome c, somatic
chr10_-_133795416 1.46 ENST00000540159.1
ENST00000368636.4
BNIP3
BCL2/adenovirus E1B 19kDa interacting protein 3
chr4_+_41362796 1.41 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1
LIM and calponin homology domains 1
chr21_-_43346790 1.41 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr8_-_66546439 1.37 ENST00000276569.3
ARMC1
armadillo repeat containing 1
chr10_-_15413035 1.36 ENST00000378116.4
ENST00000455654.1
FAM171A1
family with sequence similarity 171, member A1
chr8_-_134309335 1.36 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1
N-myc downstream regulated 1
chr8_-_122653630 1.35 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr1_+_200708671 1.35 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr8_-_130951940 1.33 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
FAM49B
family with sequence similarity 49, member B
chr15_+_44829255 1.33 ENST00000261868.5
ENST00000424492.3
EIF3J
eukaryotic translation initiation factor 3, subunit J
chr1_+_93913713 1.33 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr11_-_110167352 1.32 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX
radixin
chr3_-_32022733 1.32 ENST00000438237.2
ENST00000396556.2
OSBPL10
oxysterol binding protein-like 10
chr17_-_1303462 1.30 ENST00000573026.1
ENST00000575977.1
ENST00000571732.1
ENST00000264335.8
YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
chr5_+_65440032 1.28 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr2_-_96931679 1.28 ENST00000258439.3
ENST00000432959.1
TMEM127
transmembrane protein 127
chr12_+_123237321 1.27 ENST00000280557.6
ENST00000455982.2
DENR
density-regulated protein
chr15_-_55562582 1.26 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr1_-_231560790 1.25 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr7_+_6414128 1.25 ENST00000348035.4
ENST00000356142.4
RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
chr21_-_44846999 1.24 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr2_-_100106419 1.24 ENST00000393445.3
ENST00000258428.3
REV1
REV1, polymerase (DNA directed)
chr7_+_43622664 1.24 ENST00000319357.5
STK17A
serine/threonine kinase 17a
chr4_+_146402925 1.23 ENST00000302085.4
SMAD1
SMAD family member 1
chr8_+_61429416 1.21 ENST00000262646.7
ENST00000531289.1
RAB2A
RAB2A, member RAS oncogene family
chr17_-_41174424 1.21 ENST00000355653.3
VAT1
vesicle amine transport 1
chr2_-_200322723 1.21 ENST00000417098.1
SATB2
SATB homeobox 2
chr17_-_48943706 1.19 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chr7_+_23145366 1.17 ENST00000339077.5
ENST00000322275.5
ENST00000539124.1
ENST00000542558.1
KLHL7
kelch-like family member 7
chr7_-_26904317 1.16 ENST00000345317.2
SKAP2
src kinase associated phosphoprotein 2
chr17_+_2496971 1.16 ENST00000397195.5
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr3_+_15247686 1.15 ENST00000253693.2
CAPN7
calpain 7
chr1_-_153935983 1.14 ENST00000537590.1
ENST00000356205.4
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr14_+_105331596 1.14 ENST00000556508.1
ENST00000414716.3
ENST00000453495.1
ENST00000418279.1
CEP170B
centrosomal protein 170B
chr14_+_67826709 1.10 ENST00000256383.4
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr7_-_137686791 1.08 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
CREB3L2
cAMP responsive element binding protein 3-like 2
chr2_+_28615669 1.08 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr1_+_110527308 1.08 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr3_+_142720366 1.07 ENST00000493782.1
ENST00000397933.2
ENST00000473835.2
ENST00000493598.2
U2SURP
U2 snRNP-associated SURP domain containing
chr3_-_133380731 1.07 ENST00000260810.5
TOPBP1
topoisomerase (DNA) II binding protein 1
chr16_+_87425381 1.06 ENST00000268607.5
MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
chr17_-_57184064 1.05 ENST00000262294.7
TRIM37
tripartite motif containing 37
chr3_-_87040233 1.03 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr11_+_45825896 1.03 ENST00000314134.3
SLC35C1
solute carrier family 35 (GDP-fucose transporter), member C1
chr12_-_26278030 1.02 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr18_+_19749386 1.02 ENST00000269216.3
GATA6
GATA binding protein 6
chr3_-_195270162 1.00 ENST00000438848.1
ENST00000328432.3
PPP1R2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr5_-_43557129 0.99 ENST00000514514.1
ENST00000504075.1
ENST00000306846.3
ENST00000436644.2
PAIP1
poly(A) binding protein interacting protein 1
chrX_-_67653614 0.99 ENST00000355520.5
OPHN1
oligophrenin 1
chr5_+_118407053 0.99 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr12_-_31479045 0.97 ENST00000539409.1
ENST00000395766.1
FAM60A
family with sequence similarity 60, member A
chr18_-_54305658 0.97 ENST00000586262.1
ENST00000217515.6
TXNL1
thioredoxin-like 1
chr14_+_23340822 0.96 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr16_-_29910365 0.96 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr1_+_201798269 0.96 ENST00000361565.4
IPO9
importin 9
chr1_+_84543734 0.95 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr18_+_29077990 0.95 ENST00000261590.8
DSG2
desmoglein 2
chr9_-_35732362 0.95 ENST00000314888.9
ENST00000540444.1
TLN1
talin 1
chr6_+_88182643 0.95 ENST00000369556.3
ENST00000544441.1
ENST00000369552.4
ENST00000369557.5
SLC35A1
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr7_+_156931606 0.94 ENST00000348165.5
UBE3C
ubiquitin protein ligase E3C
chr10_+_114709999 0.94 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr19_+_1752372 0.93 ENST00000382349.4
ONECUT3
one cut homeobox 3
chrX_+_12809463 0.93 ENST00000380663.3
ENST00000380668.5
ENST00000398491.2
ENST00000489404.1
PRPS2
phosphoribosyl pyrophosphate synthetase 2
chr4_-_89744457 0.93 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr6_-_86352642 0.90 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr15_+_39873268 0.90 ENST00000397591.2
ENST00000260356.5
THBS1
thrombospondin 1
chr5_-_114880533 0.90 ENST00000274457.3
FEM1C
fem-1 homolog c (C. elegans)
chr1_+_93811438 0.90 ENST00000370272.4
ENST00000370267.1
DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr11_+_70244510 0.89 ENST00000346329.3
ENST00000301843.8
ENST00000376561.3
CTTN
cortactin
chr10_-_65225722 0.89 ENST00000399251.1
JMJD1C
jumonji domain containing 1C
chr19_-_45908292 0.88 ENST00000360957.5
ENST00000592134.1
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr1_+_26606608 0.88 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr8_+_101170257 0.87 ENST00000251809.3
SPAG1
sperm associated antigen 1
chr6_-_139695757 0.86 ENST00000367651.2
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr8_-_124054587 0.86 ENST00000259512.4
DERL1
derlin 1
chr6_+_117996621 0.86 ENST00000368494.3
NUS1
nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
chr16_-_20911641 0.86 ENST00000564349.1
ENST00000324344.4
ERI2
DCUN1D3
ERI1 exoribonuclease family member 2
DCN1, defective in cullin neddylation 1, domain containing 3
chr3_-_136471204 0.85 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
STAG1
stromal antigen 1
chr22_+_18121562 0.84 ENST00000355028.3
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr7_+_18535346 0.83 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9
histone deacetylase 9
chr20_+_30865429 0.82 ENST00000375712.3
KIF3B
kinesin family member 3B
chr14_-_75179774 0.82 ENST00000555249.1
ENST00000556202.1
ENST00000356357.4
ENST00000338772.5
AREL1
AC007956.1
apoptosis resistant E3 ubiquitin protein ligase 1
Full-length cDNA 5-PRIME end of clone CS0CAP004YO05 of Thymus of Homo sapiens (human); Uncharacterized protein
chr8_+_133787586 0.81 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1
PHD finger protein 20-like 1
chr1_-_51763661 0.79 ENST00000530004.1
TTC39A
tetratricopeptide repeat domain 39A
chr21_+_37692481 0.78 ENST00000400485.1
MORC3
MORC family CW-type zinc finger 3

Network of associatons between targets according to the STRING database.

First level regulatory network of UUGGCAA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
1.2 3.6 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
1.1 3.2 GO:0002188 translation reinitiation(GO:0002188)
0.8 1.7 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.8 2.4 GO:0032765 lymphotoxin A production(GO:0032641) positive regulation of mast cell cytokine production(GO:0032765) lymphotoxin A biosynthetic process(GO:0042109)
0.8 9.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.7 2.8 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.7 2.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.7 0.7 GO:0032808 lacrimal gland development(GO:0032808)
0.7 2.0 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.7 2.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.6 1.9 GO:0044209 AMP salvage(GO:0044209)
0.6 1.9 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.6 1.7 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.6 2.3 GO:0031291 Ran protein signal transduction(GO:0031291)
0.6 2.8 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.5 1.6 GO:0003383 apical constriction(GO:0003383)
0.5 2.7 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.5 1.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.5 2.7 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.5 1.5 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.5 2.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.5 3.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.5 1.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.5 2.8 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.5 1.8 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.4 1.7 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.4 1.7 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.4 2.1 GO:2000301 regulation of intracellular transport of viral material(GO:1901252) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.4 1.7 GO:0035523 protein K29-linked deubiquitination(GO:0035523) maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.4 1.7 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.4 1.2 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.4 4.1 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.4 2.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.4 3.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.4 1.8 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.4 1.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.3 1.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.3 1.0 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.3 3.4 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.3 4.2 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.3 1.2 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.3 0.9 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.3 4.5 GO:0070831 basement membrane assembly(GO:0070831)
0.3 2.4 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.3 3.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.3 1.9 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.3 2.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.3 1.6 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.3 2.9 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.3 1.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 4.1 GO:0045116 protein neddylation(GO:0045116)
0.2 3.7 GO:0006449 regulation of translational termination(GO:0006449)
0.2 2.0 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 1.0 GO:0097338 response to clozapine(GO:0097338)
0.2 1.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 0.7 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.2 1.3 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.2 0.9 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.2 1.5 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.2 1.3 GO:0043316 cytotoxic T cell degranulation(GO:0043316) positive regulation of constitutive secretory pathway(GO:1903435)
0.2 0.6 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
0.2 1.2 GO:0051342 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.2 2.8 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.2 3.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 0.9 GO:0003164 His-Purkinje system development(GO:0003164)
0.2 1.9 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.2 0.9 GO:0006167 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) AMP biosynthetic process(GO:0006167) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 1.6 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.2 0.9 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 0.7 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.2 0.5 GO:0061198 fungiform papilla formation(GO:0061198)
0.2 0.5 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.2 1.5 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.2 1.7 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.2 0.9 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2 0.6 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.2 1.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 1.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 0.6 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.7 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 0.4 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.4 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.9 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 2.7 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 1.4 GO:0045176 apical protein localization(GO:0045176)
0.1 0.3 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.1 0.5 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.4 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.7 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 1.4 GO:0090232 peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232)
0.1 0.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 4.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.2 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 1.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.6 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 1.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 1.6 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 2.4 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.6 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 1.9 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.5 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 1.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 1.2 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.1 0.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.9 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.1 4.2 GO:0048286 lung alveolus development(GO:0048286)
0.1 0.3 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.7 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 2.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.0 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1 2.0 GO:0019054 modulation by virus of host process(GO:0019054)
0.1 1.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 2.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 1.8 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 1.3 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.1 0.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 1.0 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.4 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.6 GO:1901727 protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.3 GO:0045906 regulation of vascular smooth muscle contraction(GO:0003056) negative regulation of vasoconstriction(GO:0045906)
0.1 3.9 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.1 0.5 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.7 GO:0042262 DNA protection(GO:0042262)
0.1 1.0 GO:0007032 endosome organization(GO:0007032)
0.1 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 1.8 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 1.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.6 GO:0060352 cell adhesion molecule production(GO:0060352)
0.1 1.4 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 0.2 GO:0006172 ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.1 0.5 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.1 2.9 GO:0035329 hippo signaling(GO:0035329)
0.1 0.5 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1 0.4 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 2.3 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 1.3 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.9 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.1 0.2 GO:0048627 myoblast development(GO:0048627) positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.1 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.1 0.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.2 GO:0002076 osteoblast development(GO:0002076)
0.1 1.3 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 1.6 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.2 GO:0071233 cellular response to leucine(GO:0071233)
0.1 2.1 GO:0046039 GTP metabolic process(GO:0046039)
0.1 0.9 GO:0033622 integrin activation(GO:0033622)
0.1 0.3 GO:0051013 microtubule severing(GO:0051013)
0.1 0.1 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.4 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.9 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 3.4 GO:0048207 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 1.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.2 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 1.7 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 1.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:1903421 regulation of synaptic vesicle recycling(GO:1903421)
0.0 2.1 GO:0043297 apical junction assembly(GO:0043297)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.5 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.3 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 4.0 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.3 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.0 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 3.8 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.8 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 2.2 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.5 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 1.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.6 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 1.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.7 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.3 GO:0051348 negative regulation of transferase activity(GO:0051348)
0.0 0.4 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0 0.3 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.3 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.7 GO:0033260 nuclear DNA replication(GO:0033260)
0.0 0.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.5 GO:0051168 nuclear export(GO:0051168)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.7 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.0 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:0005606 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.7 2.1 GO:0019034 viral replication complex(GO:0019034)
0.6 1.7 GO:0005588 collagen type V trimer(GO:0005588)
0.6 2.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.5 2.4 GO:0032449 CBM complex(GO:0032449) lipopolysaccharide receptor complex(GO:0046696)
0.4 5.7 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.4 0.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.4 1.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.4 4.6 GO:0016600 flotillin complex(GO:0016600)
0.3 1.0 GO:0043291 RAVE complex(GO:0043291)
0.3 2.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 1.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.3 0.8 GO:0005873 plus-end kinesin complex(GO:0005873)
0.3 3.8 GO:0031209 SCAR complex(GO:0031209)
0.3 2.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.2 0.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 0.9 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 4.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 2.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 0.9 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.2 1.9 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 4.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 2.7 GO:0097227 sperm annulus(GO:0097227)
0.2 2.5 GO:0005577 fibrinogen complex(GO:0005577)
0.2 3.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 2.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 1.5 GO:0045180 basal cortex(GO:0045180)
0.1 0.6 GO:0045160 myosin I complex(GO:0045160)
0.1 1.9 GO:0005916 fascia adherens(GO:0005916)
0.1 1.2 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 0.1 GO:0070876 SOSS complex(GO:0070876)
0.1 1.1 GO:0051286 cell tip(GO:0051286)
0.1 0.7 GO:0097422 tubular endosome(GO:0097422)
0.1 0.9 GO:0097452 GAIT complex(GO:0097452)
0.1 0.9 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 2.2 GO:0000145 exocyst(GO:0000145)
0.1 1.9 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 1.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 2.1 GO:0042588 zymogen granule(GO:0042588)
0.1 0.3 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 1.6 GO:0032059 bleb(GO:0032059)
0.1 1.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.5 GO:0032433 filopodium tip(GO:0032433)
0.1 2.2 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 6.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 3.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.8 GO:0044754 autolysosome(GO:0044754)
0.1 1.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 2.4 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 1.5 GO:0016235 aggresome(GO:0016235)
0.1 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.1 6.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.8 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.6 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.2 GO:0071141 SMAD protein complex(GO:0071141)
0.1 2.2 GO:0031941 filamentous actin(GO:0031941)
0.1 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 3.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0005912 adherens junction(GO:0005912)
0.0 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 26.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 2.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 2.4 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 4.4 GO:0043296 apical junction complex(GO:0043296)
0.0 2.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.7 GO:0000242 pericentriolar material(GO:0000242)
0.0 4.0 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0043034 costamere(GO:0043034)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.5 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 2.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 3.5 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.2 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.9 GO:0000502 proteasome complex(GO:0000502)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0097440 apical dendrite(GO:0097440)
0.0 13.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.2 GO:1990752 microtubule end(GO:1990752)
0.0 1.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 4.0 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.7 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.6 GO:0030175 filopodium(GO:0030175)
0.0 4.2 GO:0016607 nuclear speck(GO:0016607)
0.0 1.4 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
1.2 4.6 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.9 2.7 GO:0032427 GBD domain binding(GO:0032427)
0.8 4.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.8 3.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.7 2.2 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.6 3.8 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.6 1.7 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.6 2.3 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.6 1.7 GO:1904288 BAT3 complex binding(GO:1904288)
0.5 2.6 GO:0034046 poly(G) binding(GO:0034046)
0.5 1.5 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.5 1.8 GO:0038025 glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
0.5 1.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.4 1.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 2.8 GO:0004849 uridine kinase activity(GO:0004849)
0.3 1.0 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.3 1.2 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.3 1.8 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.3 0.9 GO:0070052 collagen V binding(GO:0070052)
0.3 3.7 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.3 3.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 1.7 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.2 1.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 1.3 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.2 0.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 2.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 2.1 GO:0019206 nucleoside kinase activity(GO:0019206)
0.2 0.6 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.2 3.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 1.3 GO:0050815 phosphoserine binding(GO:0050815)
0.2 2.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.2 1.8 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 2.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 1.6 GO:0033592 RNA strand annealing activity(GO:0033592)
0.2 1.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 4.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 1.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 2.9 GO:0043422 protein kinase B binding(GO:0043422)
0.2 3.2 GO:0008603 cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 0.9 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 0.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 0.9 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 2.9 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.7 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 1.8 GO:0034452 dynactin binding(GO:0034452)
0.1 0.7 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1 1.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.0 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791) protein-disulfide reductase activity(GO:0047134)
0.1 0.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 1.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 4.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 4.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.7 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1 0.9 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 1.0 GO:0043426 MRF binding(GO:0043426)
0.1 1.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 7.3 GO:0019003 GDP binding(GO:0019003)
0.1 1.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.4 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 2.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 1.7 GO:0070330 aromatase activity(GO:0070330)
0.1 1.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 6.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 2.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 2.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 4.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 2.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.9 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 5.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 1.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 0.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.1 GO:0008494 translation activator activity(GO:0008494)
0.1 1.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 3.0 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.9 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 6.4 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.9 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 1.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.9 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.5 GO:0002020 protease binding(GO:0002020)
0.0 0.9 GO:0008143 poly(A) binding(GO:0008143)
0.0 16.0 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 3.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 2.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 1.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 5.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.6 GO:0005123 death receptor binding(GO:0005123)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.9 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 2.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.0 GO:0017040 ceramidase activity(GO:0017040)
0.0 1.3 GO:0005496 steroid binding(GO:0005496)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 1.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 1.6 PID FOXO PATHWAY FoxO family signaling
0.2 4.5 PID ARF 3PATHWAY Arf1 pathway
0.1 10.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 9.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 3.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 5.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 5.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 1.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.7 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 3.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 1.2 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 3.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 3.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 4.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.8 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 2.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.3 0.5 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.2 7.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 2.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 3.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 1.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 4.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 4.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.6 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 3.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 2.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 4.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 2.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.7 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 2.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 2.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.9 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 4.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 7.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 2.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 4.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 3.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 2.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 2.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 3.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.2 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.2 REACTOME DNA REPAIR Genes involved in DNA Repair