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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for VDR

Z-value: 0.19

Motif logo

Transcription factors associated with VDR

Gene Symbol Gene ID Gene Info
ENSG00000111424.6 vitamin D receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VDRhg19_v2_chr12_-_48298785_482988280.119.2e-02Click!

Activity profile of VDR motif

Sorted Z-values of VDR motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_34756219 5.38 ENST00000451448.2
ENST00000394359.3
TBC1 domain family, member 3C
TBC1 domain family, member 3H
chr17_-_34808047 5.37 ENST00000592614.1
ENST00000591542.1
ENST00000330458.7
ENST00000341264.6
ENST00000592987.1
ENST00000400684.4
TBC1 domain family, member 3G
TBC1 domain family, member 3H
chr17_-_34807272 5.30 ENST00000535592.1
ENST00000394453.1
TBC1 domain family, member 3G
chr17_-_36348610 5.29 ENST00000339023.4
ENST00000354664.4
TBC1 domain family, member 3
chr17_-_36347835 5.25 ENST00000519532.1
TBC1 domain family, member 3
chr17_+_36284791 4.95 ENST00000505415.1
TBC1 domain family, member 3F
chr22_+_18593446 4.89 ENST00000316027.6
tubulin, alpha 8
chr5_-_68665084 4.72 ENST00000509462.1
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr1_+_200993071 4.66 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
chr2_-_85625857 4.48 ENST00000453973.1
capping protein (actin filament), gelsolin-like
chr10_-_13523073 4.16 ENST00000440282.1
BEN domain containing 7
chr1_-_19426149 4.05 ENST00000429347.2
ubiquitin protein ligase E3 component n-recognin 4
chr2_-_230786619 3.89 ENST00000389045.3
ENST00000409677.1
thyroid hormone receptor interactor 12
chr18_-_6414884 3.85 ENST00000317931.7
ENST00000284898.6
ENST00000400104.3
l(3)mbt-like 4 (Drosophila)
chr2_+_111490161 3.76 ENST00000340561.4
acyl-CoA oxidase-like
chr2_-_230786679 3.73 ENST00000543084.1
ENST00000343290.5
ENST00000389044.4
ENST00000283943.5
thyroid hormone receptor interactor 12
chr5_-_179227540 3.70 ENST00000520875.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr11_-_104817919 3.67 ENST00000533252.1
caspase 4, apoptosis-related cysteine peptidase
chr6_+_31802685 3.60 ENST00000375639.2
ENST00000375638.3
ENST00000375635.2
ENST00000375642.2
ENST00000395789.1
chromosome 6 open reading frame 48
chr2_-_235405168 3.49 ENST00000339728.3
ADP-ribosylation factor-like 4C
chr3_+_54157480 3.42 ENST00000490478.1
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr17_-_34591208 3.40 ENST00000336331.5
TBC1 domain family, member 3C
chr17_-_7082861 3.38 ENST00000269299.3
asialoglycoprotein receptor 1
chr19_+_1407517 3.37 ENST00000336761.6
ENST00000233078.4
DAZ associated protein 1
chr12_-_133050726 3.36 ENST00000595994.1
mucin 8
chr10_-_43892279 3.31 ENST00000443950.2
heterogeneous nuclear ribonucleoprotein F
chr12_+_52626898 3.23 ENST00000331817.5
keratin 7
chr15_-_59949667 3.18 ENST00000396061.1
general transcription factor IIA, 2, 12kDa
chr10_-_43892668 3.16 ENST00000544000.1
heterogeneous nuclear ribonucleoprotein F
chr16_-_3767551 3.08 ENST00000246957.5
TNF receptor-associated protein 1
chr11_+_64808675 3.05 ENST00000529996.1
SAC3 domain containing 1
chr1_+_52082751 3.03 ENST00000447887.1
ENST00000435686.2
ENST00000428468.1
ENST00000453295.1
oxysterol binding protein-like 9
chr11_+_6624970 3.03 ENST00000420936.2
ENST00000528995.1
integrin-linked kinase
chr12_+_110906169 3.00 ENST00000377673.5
family with sequence similarity 216, member A
chr5_-_179051579 2.98 ENST00000505811.1
ENST00000515714.1
ENST00000513225.1
ENST00000503664.1
ENST00000356731.5
ENST00000523137.1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr15_-_59949693 2.97 ENST00000396063.1
ENST00000396064.3
ENST00000484743.1
ENST00000559706.1
ENST00000396060.2
general transcription factor IIA, 2, 12kDa
chr2_+_220363579 2.97 ENST00000313597.5
ENST00000373917.3
ENST00000358215.3
ENST00000373908.1
ENST00000455657.1
ENST00000435316.1
ENST00000341142.3
GDP-mannose pyrophosphorylase A
chr19_-_40331345 2.94 ENST00000597224.1
fibrillarin
chr12_+_10658489 2.92 ENST00000538173.1
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr17_-_79805146 2.91 ENST00000415593.1
prolyl 4-hydroxylase, beta polypeptide
chr9_+_138391805 2.80 ENST00000371785.1
mitochondrial ribosomal protein S2
chr6_-_42016385 2.77 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
cyclin D3
chr11_+_6624955 2.74 ENST00000299421.4
ENST00000537806.1
integrin-linked kinase
chr14_-_35873856 2.66 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr19_+_13261216 2.63 ENST00000587885.1
ENST00000292433.3
immediate early response 2
chr19_+_14672755 2.62 ENST00000594545.1
trans-2,3-enoyl-CoA reductase
chr11_+_6625046 2.60 ENST00000396751.2
integrin-linked kinase
chrX_+_153770421 2.52 ENST00000369609.5
ENST00000369607.1
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr16_-_3767506 2.46 ENST00000538171.1
TNF receptor-associated protein 1
chr9_+_138392483 2.44 ENST00000241600.5
mitochondrial ribosomal protein S2
chr1_+_198608146 2.42 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr3_+_180630444 2.38 ENST00000491062.1
ENST00000468861.1
ENST00000445140.2
ENST00000484958.1
fragile X mental retardation, autosomal homolog 1
chr20_+_30327063 2.37 ENST00000300403.6
ENST00000340513.4
TPX2, microtubule-associated
chr16_+_69958887 2.33 ENST00000568684.1
WW domain containing E3 ubiquitin protein ligase 2
chr3_+_180630090 2.25 ENST00000357559.4
ENST00000305586.7
fragile X mental retardation, autosomal homolog 1
chr6_+_24775153 2.23 ENST00000356509.3
ENST00000230056.3
geminin, DNA replication inhibitor
chr14_+_95047744 2.19 ENST00000553511.1
ENST00000554633.1
ENST00000555681.1
ENST00000554276.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr1_+_153750622 2.19 ENST00000532853.1
solute carrier family 27 (fatty acid transporter), member 3
chr11_-_104840093 2.18 ENST00000417440.2
ENST00000444739.2
caspase 4, apoptosis-related cysteine peptidase
chr19_+_10765699 2.08 ENST00000590009.1
interleukin enhancer binding factor 3, 90kDa
chr2_-_203736334 2.02 ENST00000392237.2
ENST00000416760.1
ENST00000412210.1
islet cell autoantigen 1,69kDa-like
chr7_-_16844611 2.02 ENST00000401412.1
ENST00000419304.2
anterior gradient 2
chr8_-_22926623 1.98 ENST00000276431.4
tumor necrosis factor receptor superfamily, member 10b
chr1_-_46152174 1.92 ENST00000290795.3
ENST00000355105.3
GC-rich promoter binding protein 1-like 1
chr21_-_15918618 1.92 ENST00000400564.1
ENST00000400566.1
SAM domain, SH3 domain and nuclear localization signals 1
chr19_+_41305085 1.91 ENST00000303961.4
egl-9 family hypoxia-inducible factor 2
chr16_+_19079215 1.90 ENST00000544894.2
ENST00000561858.1
coenzyme Q7 homolog, ubiquinone (yeast)
chr19_-_54804173 1.90 ENST00000391744.3
ENST00000251390.3
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
chr14_-_20801427 1.89 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr8_+_9046503 1.89 ENST00000512942.2
RP11-10A14.5
chr1_-_183559693 1.87 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
neutrophil cytosolic factor 2
chr9_-_139343294 1.80 ENST00000313084.5
SEC16 homolog A (S. cerevisiae)
chr9_+_71789133 1.76 ENST00000348208.4
ENST00000265384.7
tight junction protein 2
chr11_+_18433840 1.72 ENST00000541669.1
ENST00000280704.4
lactate dehydrogenase C
chr13_-_38172863 1.68 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
periostin, osteoblast specific factor
chr15_-_72563585 1.66 ENST00000287196.9
ENST00000260376.7
poly (ADP-ribose) polymerase family, member 6
chr7_-_36764004 1.63 ENST00000431169.1
acyloxyacyl hydrolase (neutrophil)
chr8_-_145028013 1.62 ENST00000354958.2
plectin
chr11_-_506316 1.61 ENST00000532055.1
ENST00000531540.1
ribonuclease/angiogenin inhibitor 1
chr15_-_59225758 1.59 ENST00000558486.1
ENST00000560682.1
ENST00000249736.7
ENST00000559880.1
ENST00000536328.1
SAFB-like, transcription modulator
chrX_-_47518498 1.58 ENST00000335890.2
ubiquitously-expressed, prefoldin-like chaperone
chr16_-_28506840 1.56 ENST00000569430.1
ceroid-lipofuscinosis, neuronal 3
chr7_+_155089486 1.56 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
insulin induced gene 1
chr8_+_12809093 1.54 ENST00000528753.2
KIAA1456
chr19_+_41281416 1.47 ENST00000597140.1
melanoma inhibitory activity
chr7_-_36764142 1.46 ENST00000258749.5
ENST00000535891.1
acyloxyacyl hydrolase (neutrophil)
chr1_-_32403370 1.45 ENST00000534796.1
protein tyrosine phosphatase type IVA, member 2
chr16_-_67281413 1.45 ENST00000258201.4
formin homology 2 domain containing 1
chr2_+_38893047 1.44 ENST00000272252.5
galactose mutarotase (aldose 1-epimerase)
chr22_-_17680472 1.41 ENST00000330232.4
cat eye syndrome chromosome region, candidate 1
chr4_-_84205905 1.38 ENST00000311461.7
ENST00000311469.4
ENST00000439031.2
coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
chr22_+_29664248 1.37 ENST00000406548.1
ENST00000437155.2
ENST00000415761.1
ENST00000331029.7
EWS RNA-binding protein 1
chr1_+_153232160 1.37 ENST00000368742.3
loricrin
chr19_-_5719860 1.36 ENST00000590729.1
lon peptidase 1, mitochondrial
chr16_+_31119615 1.36 ENST00000394950.3
ENST00000287507.3
ENST00000219794.6
ENST00000561755.1
branched chain ketoacid dehydrogenase kinase
chr16_+_19078960 1.36 ENST00000568985.1
ENST00000566110.1
coenzyme Q7 homolog, ubiquinone (yeast)
chr11_-_65667884 1.35 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOS-like antigen 1
chr16_+_19079311 1.32 ENST00000569127.1
coenzyme Q7 homolog, ubiquinone (yeast)
chr19_+_41281282 1.32 ENST00000263369.3
melanoma inhibitory activity
chr9_+_118950325 1.31 ENST00000534838.1
pregnancy-associated plasma protein A, pappalysin 1
chr7_+_65552756 1.27 ENST00000450043.1
AC068533.7
chr2_+_86333301 1.26 ENST00000254630.7
pentatricopeptide repeat domain 3
chr11_-_65667997 1.26 ENST00000312562.2
ENST00000534222.1
FOS-like antigen 1
chr3_+_157154578 1.25 ENST00000295927.3
pentraxin 3, long
chr11_-_73882029 1.24 ENST00000539061.1
C2 calcium-dependent domain containing 3
chr1_+_36348790 1.22 ENST00000373204.4
argonaute RISC catalytic component 1
chr17_+_53828333 1.19 ENST00000268896.5
phosphatidylcholine transfer protein
chr16_+_16043406 1.18 ENST00000399410.3
ENST00000399408.2
ENST00000346370.5
ENST00000351154.5
ENST00000345148.5
ENST00000349029.5
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
chr3_+_122283064 1.15 ENST00000296161.4
deltex 3-like (Drosophila)
chr10_+_47894572 1.15 ENST00000355876.5
family with sequence similarity 21, member B
chr19_+_54694119 1.12 ENST00000456872.1
ENST00000302937.4
ENST00000429671.2
TSEN34 tRNA splicing endonuclease subunit
chr19_+_41281060 1.11 ENST00000594436.1
ENST00000597784.1
melanoma inhibitory activity
chr10_+_104154229 1.10 ENST00000428099.1
ENST00000369966.3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chrX_-_135962876 1.09 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RNA binding motif protein, X-linked
chr9_+_111624577 1.08 ENST00000333999.3
actin-like 7A
chr16_-_87799505 1.08 ENST00000353170.5
ENST00000561825.1
ENST00000270583.5
ENST00000562261.1
ENST00000347925.5
kelch domain containing 4
chr7_+_155090271 1.07 ENST00000476756.1
insulin induced gene 1
chr17_-_64225508 1.06 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr15_-_59225844 1.05 ENST00000380516.2
SAFB-like, transcription modulator
chr14_-_54908043 1.04 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
cornichon family AMPA receptor auxiliary protein 1
chr7_-_72722783 1.04 ENST00000428206.1
ENST00000252594.6
ENST00000310326.8
ENST00000438747.2
NOP2/Sun domain family, member 5
chrX_-_47518527 1.04 ENST00000333119.3
ubiquitously-expressed, prefoldin-like chaperone
chr3_+_132036207 1.00 ENST00000336375.5
ENST00000495911.1
acid phosphatase, prostate
chr3_+_151986709 0.98 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
muscleblind-like splicing regulator 1
chr19_-_12595586 0.98 ENST00000397732.3
zinc finger protein 709
chr17_+_1733276 0.97 ENST00000254719.5
replication protein A1, 70kDa
chr17_+_53828381 0.97 ENST00000576183.1
phosphatidylcholine transfer protein
chr12_-_25348007 0.97 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
cancer susceptibility candidate 1
chr22_+_39077947 0.94 ENST00000216034.4
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr2_+_177134134 0.93 ENST00000249442.6
ENST00000392529.2
ENST00000443241.1
metaxin 2
chr3_-_122283100 0.91 ENST00000492382.1
ENST00000462315.1
poly (ADP-ribose) polymerase family, member 9
chr9_-_115095123 0.89 ENST00000458258.1
polypyrimidine tract binding protein 3
chr19_-_13261090 0.89 ENST00000588848.1
syntaxin 10
chr19_+_57831829 0.89 ENST00000321545.4
zinc finger protein 543
chr19_+_39936267 0.88 ENST00000359191.6
suppressor of Ty 5 homolog (S. cerevisiae)
chr19_-_13261160 0.83 ENST00000343587.5
ENST00000591197.1
syntaxin 10
chr20_-_52790512 0.82 ENST00000216862.3
cytochrome P450, family 24, subfamily A, polypeptide 1
chr22_+_45705728 0.82 ENST00000441876.2
family with sequence similarity 118, member A
chr8_-_22926526 0.79 ENST00000347739.3
ENST00000542226.1
tumor necrosis factor receptor superfamily, member 10b
chr8_+_24298597 0.79 ENST00000380789.1
ADAM metallopeptidase domain 7
chr12_+_3069037 0.78 ENST00000397122.2
TEA domain family member 4
chr12_-_110906027 0.78 ENST00000537466.2
ENST00000550974.1
ENST00000228827.3
GPN-loop GTPase 3
chr1_+_92414928 0.78 ENST00000362005.3
ENST00000370389.2
ENST00000399546.2
ENST00000423434.1
ENST00000394530.3
ENST00000440509.1
bromodomain, testis-specific
chr10_-_32345305 0.77 ENST00000302418.4
kinesin family member 5B
chrX_-_48776292 0.76 ENST00000376509.4
pim-2 oncogene
chr14_-_91884150 0.76 ENST00000553403.1
coiled-coil domain containing 88C
chr11_-_60719213 0.76 ENST00000227880.3
solute carrier family 15 (oligopeptide transporter), member 3
chr6_+_31583761 0.75 ENST00000376049.4
allograft inflammatory factor 1
chr2_-_232329186 0.75 ENST00000322723.4
nucleolin
chr2_+_231280908 0.74 ENST00000427101.2
ENST00000432979.1
SP100 nuclear antigen
chr10_+_5454505 0.72 ENST00000355029.4
neuroepithelial cell transforming 1
chr8_+_24298531 0.71 ENST00000175238.6
ADAM metallopeptidase domain 7
chr19_+_39936186 0.68 ENST00000432763.2
ENST00000402194.2
ENST00000601515.1
suppressor of Ty 5 homolog (S. cerevisiae)
chr9_-_130617029 0.68 ENST00000373203.4
endoglin
chr4_-_164534657 0.68 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr7_+_129015484 0.67 ENST00000490911.1
adenosylhomocysteinase-like 2
chr16_+_31044812 0.67 ENST00000313843.3
syntaxin 4
chr1_-_241799232 0.64 ENST00000366553.1
choroideremia-like (Rab escort protein 2)
chr17_-_40288449 0.63 ENST00000552162.1
ENST00000550504.1
RAB5C, member RAS oncogene family
chr8_+_119294456 0.62 ENST00000366457.2
Uncharacterized protein
chr22_+_50624323 0.61 ENST00000380909.4
ENST00000303434.4
TraB domain containing
chr8_+_98900132 0.61 ENST00000520016.1
matrilin 2
chr1_+_175036966 0.61 ENST00000239462.4
tenascin N
chr12_+_53895364 0.61 ENST00000552817.1
ENST00000394357.2
TAR (HIV-1) RNA binding protein 2
chrX_+_100646190 0.60 ENST00000471855.1
ribosomal protein L36a
chr7_+_120590803 0.60 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
inhibitor of growth family, member 3
chr13_-_33859819 0.58 ENST00000336934.5
StAR-related lipid transfer (START) domain containing 13
chr10_+_54074033 0.57 ENST00000373970.3
dickkopf WNT signaling pathway inhibitor 1
chr6_+_35227449 0.56 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
zinc finger protein 76
chr1_-_27226928 0.56 ENST00000361720.5
G patch domain containing 3
chr5_-_145562147 0.55 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
leucyl-tRNA synthetase
chr9_-_130616915 0.54 ENST00000344849.3
endoglin
chr1_-_205091115 0.53 ENST00000264515.6
ENST00000367164.1
retinoblastoma binding protein 5
chr3_+_184033135 0.53 ENST00000424196.1
eukaryotic translation initiation factor 4 gamma, 1
chr10_-_33623564 0.53 ENST00000374875.1
ENST00000374822.4
neuropilin 1
chr5_-_82969405 0.53 ENST00000510978.1
hyaluronan and proteoglycan link protein 1
chr16_+_57392684 0.51 ENST00000219235.4
chemokine (C-C motif) ligand 22
chr22_-_29663954 0.50 ENST00000216085.7
rhomboid domain containing 3
chr14_-_23398565 0.49 ENST00000397440.4
ENST00000538452.1
ENST00000421938.2
ENST00000554867.1
ENST00000556616.1
ENST00000216350.8
ENST00000553550.1
ENST00000397441.2
ENST00000553897.1
protein arginine methyltransferase 5
chr11_+_63998198 0.49 ENST00000321460.5
DnaJ (Hsp40) homolog, subfamily C, member 4
chr8_+_95653373 0.47 ENST00000358397.5
epithelial splicing regulatory protein 1
chr4_+_144434584 0.45 ENST00000283131.3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chrX_+_100645812 0.43 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr4_+_17579110 0.43 ENST00000606142.1
leucine aminopeptidase 3
chr1_+_100111580 0.43 ENST00000605497.1
palmdelphin
chr1_-_221915418 0.42 ENST00000323825.3
ENST00000366899.3
dual specificity phosphatase 10
chr19_+_14017116 0.41 ENST00000589606.1
coiled-coil and C2 domain containing 1A
chr5_-_39270725 0.41 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr16_-_31105870 0.40 ENST00000394971.3
vitamin K epoxide reductase complex, subunit 1
chr8_+_23104130 0.40 ENST00000313219.7
ENST00000519984.1
charged multivesicular body protein 7
chr5_-_7869108 0.39 ENST00000264669.5
ENST00000507572.1
ENST00000504695.1
FAST kinase domains 3
chr6_-_32557610 0.38 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr3_+_190105909 0.37 ENST00000456423.1
claudin 16
chr19_-_49122384 0.37 ENST00000550973.1
ENST00000550645.1
ENST00000549273.1
ENST00000552588.1
ribosomal protein L18
chr4_+_142557771 0.36 ENST00000514653.1
interleukin 15
chr1_-_174992544 0.36 ENST00000476371.1
mitochondrial ribosomal protein S14
chr9_-_138391692 0.36 ENST00000429260.2
chromosome 9 open reading frame 116
chr22_+_29664305 0.35 ENST00000414183.2
ENST00000333395.6
ENST00000455726.1
ENST00000332035.6
EWS RNA-binding protein 1
chr1_-_75198940 0.34 ENST00000417775.1
crystallin, zeta (quinone reductase)
chr6_+_79577189 0.33 ENST00000369940.2
interleukin-1 receptor-associated kinase 1 binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of VDR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 GO:0009386 translational attenuation(GO:0009386)
1.1 7.6 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.9 2.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.7 2.9 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.6 4.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.6 1.7 GO:1990523 bone regeneration(GO:1990523)
0.5 5.8 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.5 2.4 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
0.5 1.4 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.5 1.4 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.4 2.7 GO:0070417 cellular response to cold(GO:0070417) nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.4 2.2 GO:0061107 seminal vesicle development(GO:0061107)
0.4 2.6 GO:0007296 vitellogenesis(GO:0007296)
0.4 1.2 GO:0001300 chronological cell aging(GO:0001300)
0.4 1.6 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.4 1.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.4 2.2 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.4 4.7 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.4 29.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.3 2.0 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.3 1.0 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.3 2.6 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.3 1.2 GO:0021997 neural plate axis specification(GO:0021997)
0.3 8.4 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.3 5.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3 1.7 GO:0019249 lactate biosynthetic process(GO:0019249)
0.3 1.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.3 0.8 GO:0042369 vitamin D catabolic process(GO:0042369)
0.3 0.8 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.3 3.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.3 1.0 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.2 1.2 GO:0052405 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199) negative regulation by host of symbiont molecular function(GO:0052405)
0.2 1.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 0.7 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 4.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 1.9 GO:0051026 chiasma assembly(GO:0051026)
0.2 0.6 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 4.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 1.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.2 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 0.6 GO:0009996 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.2 0.5 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425) valyl-tRNA aminoacylation(GO:0006438)
0.2 4.6 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.2 1.8 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.2 1.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.2 1.0 GO:0070475 rRNA base methylation(GO:0070475)
0.2 0.8 GO:0097102 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 0.9 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 0.8 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.1 2.8 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 1.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 3.7 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.5 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 0.5 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 1.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.4 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 6.1 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 0.7 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.1 1.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 2.6 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 1.6 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.6 GO:0035087 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.1 6.9 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1 1.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.9 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 3.7 GO:0032456 endocytic recycling(GO:0032456)
0.1 6.5 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 0.4 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 0.6 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.4 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.1 0.2 GO:0051039 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 0.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.2 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 2.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 3.0 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 0.7 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 0.2 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.1 3.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 2.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 1.9 GO:0045730 respiratory burst(GO:0045730)
0.1 0.7 GO:0051451 myoblast migration(GO:0051451)
0.1 2.3 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 1.0 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 1.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.9 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 1.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.1 2.5 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 1.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 5.0 GO:0070268 cornification(GO:0070268)
0.0 0.4 GO:0045333 cellular respiration(GO:0045333)
0.0 1.1 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 1.8 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 6.2 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 1.6 GO:0006954 inflammatory response(GO:0006954)
0.0 0.5 GO:0035966 response to unfolded protein(GO:0006986) response to topologically incorrect protein(GO:0035966)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 2.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 2.6 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 1.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.3 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.8 GO:0035329 hippo signaling(GO:0035329)
0.0 3.4 GO:0061337 cardiac conduction(GO:0061337)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 4.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 4.3 GO:0006413 translational initiation(GO:0006413)
0.0 0.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.3 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 1.6 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.6 GO:0008347 glial cell migration(GO:0008347)
0.0 0.5 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.6 GO:0006402 mRNA catabolic process(GO:0006402)
0.0 0.8 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 1.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.2 GO:0010922 positive regulation of phosphatase activity(GO:0010922)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
1.0 5.8 GO:0072557 IPAF inflammasome complex(GO:0072557)
1.0 2.9 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.8 6.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.7 2.2 GO:0097179 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) protease inhibitor complex(GO:0097179) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.7 2.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.6 4.7 GO:0070761 pre-snoRNP complex(GO:0070761)
0.4 1.2 GO:0072563 endothelial microparticle(GO:0072563)
0.4 1.6 GO:0032044 DSIF complex(GO:0032044)
0.3 3.8 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.3 4.5 GO:0008290 F-actin capping protein complex(GO:0008290) Flemming body(GO:0090543)
0.3 14.6 GO:0043034 costamere(GO:0043034)
0.3 1.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.3 1.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.3 1.6 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.2 1.9 GO:0032010 phagolysosome(GO:0032010)
0.2 1.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 5.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 1.8 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.2 2.4 GO:0043203 axon hillock(GO:0043203)
0.2 2.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 0.6 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 0.5 GO:0031213 RSF complex(GO:0031213)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.0 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.9 GO:0001726 ruffle(GO:0001726)
0.1 2.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.4 GO:0032059 bleb(GO:0032059)
0.1 0.7 GO:0000322 storage vacuole(GO:0000322)
0.1 3.5 GO:0045095 keratin filament(GO:0045095)
0.1 1.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.9 GO:0000795 synaptonemal complex(GO:0000795)
0.1 1.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 6.8 GO:0005811 lipid particle(GO:0005811)
0.1 9.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 11.8 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.8 GO:0002116 semaphorin receptor complex(GO:0002116) sorting endosome(GO:0097443)
0.1 5.9 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 3.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.5 GO:0034709 methylosome(GO:0034709)
0.0 1.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.4 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.1 GO:0042627 chylomicron(GO:0042627)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 4.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 3.9 GO:0030175 filopodium(GO:0030175)
0.0 1.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 7.9 GO:0016607 nuclear speck(GO:0016607)
0.0 2.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.7 GO:0005819 spindle(GO:0005819)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.5 GO:0031514 motile cilium(GO:0031514)
0.0 0.2 GO:0097546 ciliary base(GO:0097546)
0.0 1.5 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.8 3.8 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.7 2.6 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.6 2.9 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.5 3.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.5 2.8 GO:0045569 TRAIL binding(GO:0045569)
0.5 1.4 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.4 3.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.4 4.6 GO:0002151 G-quadruplex RNA binding(GO:0002151) RNA strand annealing activity(GO:0033592)
0.4 5.8 GO:0050700 CARD domain binding(GO:0050700)
0.4 1.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.4 1.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.4 1.5 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.3 4.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 12.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.3 1.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.3 1.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.3 1.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 1.9 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.3 0.8 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.2 1.7 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.2 2.2 GO:0032190 acrosin binding(GO:0032190)
0.2 3.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 2.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.2 1.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 2.9 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.2 34.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 0.8 GO:0099609 microtubule lateral binding(GO:0099609)
0.2 1.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 0.5 GO:0004819 glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.2 7.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.2 2.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 0.7 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 0.8 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.2 1.6 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.2 1.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 2.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.2 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.2 GO:0005534 galactose binding(GO:0005534)
0.1 3.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.0 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.7 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.5 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 1.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 5.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 3.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.3 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 1.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 2.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 2.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 3.0 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.0 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 2.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.9 GO:0015266 protein channel activity(GO:0015266)
0.1 0.3 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 1.2 GO:0035198 miRNA binding(GO:0035198)
0.1 1.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 2.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.3 GO:0070404 NADH binding(GO:0070404)
0.1 0.6 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 1.6 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.6 GO:0039706 co-receptor binding(GO:0039706)
0.0 3.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 9.0 GO:0005178 integrin binding(GO:0005178)
0.0 1.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 3.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 7.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 2.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 2.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.3 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 2.8 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 1.4 GO:0043621 protein self-association(GO:0043621)
0.0 3.1 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 3.4 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 3.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.6 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.6 GO:0004402 histone acetyltransferase activity(GO:0004402)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 6.2 ST GAQ PATHWAY G alpha q Pathway
0.1 4.7 PID MYC PATHWAY C-MYC pathway
0.1 1.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 2.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 2.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 2.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 2.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 4.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 3.1 PID E2F PATHWAY E2F transcription factor network
0.0 2.9 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 1.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 2.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 2.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 2.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 3.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 10.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 1.6 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.2 3.8 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 3.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 5.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 2.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 2.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 10.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 0.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 2.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 3.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 12.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.9 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 1.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 1.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation