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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for ZBED1

Z-value: 0.60

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Transcription factors associated with ZBED1

Gene Symbol Gene ID Gene Info
ENSG00000214717.5 zinc finger BED-type containing 1
ENSGR0000214717.5 zinc finger BED-type containing 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBED1hg19_v2_chrX_-_2418596_24186210.441.6e-11Click!

Activity profile of ZBED1 motif

Sorted Z-values of ZBED1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_151254738 10.51 ENST00000336715.6
ENST00000324048.5
ENST00000368879.2
zinc finger protein 687
chr1_+_36023370 5.83 ENST00000356090.4
ENST00000373243.2
neurochondrin
chr7_+_139025875 5.65 ENST00000297534.6
chromosome 7 open reading frame 55
chr17_+_4843654 5.23 ENST00000575111.1
ring finger protein 167
chr17_+_4843413 5.08 ENST00000572430.1
ENST00000262482.6
ring finger protein 167
chr17_+_4843679 4.78 ENST00000576229.1
ring finger protein 167
chr17_-_4843316 4.34 ENST00000544061.2
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr17_+_4843303 3.70 ENST00000571816.1
ring finger protein 167
chr9_+_33290491 3.46 ENST00000379540.3
ENST00000379521.4
ENST00000318524.6
nuclear transcription factor, X-box binding 1
chr19_+_54641444 3.23 ENST00000221232.5
ENST00000358389.3
CCR4-NOT transcription complex, subunit 3
chr8_+_38089198 3.16 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
DDHD domain containing 2
chr22_+_19701985 2.97 ENST00000455784.2
ENST00000406395.1
septin 5
chrX_-_53711064 2.87 ENST00000342160.3
ENST00000446750.1
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
chr17_-_4843206 2.37 ENST00000576951.1
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chrX_-_63615297 1.63 ENST00000374852.3
ENST00000453546.1
myotubularin related protein 8
chr22_-_36424458 0.17 ENST00000438146.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_-_184723942 0.03 ENST00000318130.8
ER degradation enhancer, mannosidase alpha-like 3

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBED1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.7 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.4 3.5 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.3 3.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 3.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 3.2 GO:0034389 lipid particle organization(GO:0034389)
0.1 5.8 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 21.7 GO:0000209 protein polyubiquitination(GO:0000209)
0.1 1.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 3.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 3.0 GO:0043195 terminal bouton(GO:0043195)
0.0 2.9 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 5.8 GO:0030424 axon(GO:0030424)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.7 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 1.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 3.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 21.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 3.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 3.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 2.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 2.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation