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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for ZBTB16

Z-value: 0.67

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Transcription factors associated with ZBTB16

Gene Symbol Gene ID Gene Info
ZBTB16
ENSG00000109906.9 zinc finger and BTB domain containing 16

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB16hg19_v2_chr11_+_113930291_113930339-0.451.7e-12Click!

Activity profile of ZBTB16 motif

Sorted Z-values of ZBTB16 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_62538089 23.35 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chr5_+_159848807 12.29 ENST00000352433.5
PTTG1
pituitary tumor-transforming 1
chr5_+_159848854 11.74 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1
pituitary tumor-transforming 1
chr1_+_156095951 10.99 ENST00000448611.2
ENST00000368297.1
LMNA
lamin A/C
chr3_-_146262488 10.50 ENST00000487389.1
PLSCR1
phospholipid scramblase 1
chr15_+_75628232 9.26 ENST00000267935.8
ENST00000567195.1
COMMD4
COMM domain containing 4
chr15_+_75628394 9.18 ENST00000564815.1
ENST00000338995.6
COMMD4
COMM domain containing 4
chr15_+_75628419 9.17 ENST00000567377.1
ENST00000562789.1
ENST00000568301.1
COMMD4
COMM domain containing 4
chr1_-_246357029 8.60 ENST00000391836.2
SMYD3
SET and MYND domain containing 3
chr15_-_55562479 8.57 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr16_+_14726672 8.00 ENST00000261658.2
ENST00000563971.1
BFAR
bifunctional apoptosis regulator
chr7_-_32534850 7.62 ENST00000409952.3
ENST00000409909.3
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_102413726 7.56 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr12_+_118454500 7.25 ENST00000537315.1
ENST00000229043.3
ENST00000484086.2
ENST00000420967.1
ENST00000454402.2
ENST00000392542.2
ENST00000535092.1
RFC5
replication factor C (activator 1) 5, 36.5kDa
chr2_+_242289502 7.17 ENST00000451310.1
SEPT2
septin 2
chr21_-_35284635 7.10 ENST00000429238.1
AP000304.12
AP000304.12
chr16_-_85722530 7.01 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr13_+_76123883 6.79 ENST00000377595.3
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr19_+_36142147 6.54 ENST00000590618.1
COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chrX_+_118602363 6.53 ENST00000317881.8
SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr3_-_146262637 6.45 ENST00000472349.1
ENST00000342435.4
PLSCR1
phospholipid scramblase 1
chr1_-_115292591 6.40 ENST00000438362.2
CSDE1
cold shock domain containing E1, RNA-binding
chr19_+_9296279 6.24 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr1_+_100731749 6.21 ENST00000370128.4
ENST00000260563.4
RTCA
RNA 3'-terminal phosphate cyclase
chr5_-_34919094 6.21 ENST00000341754.4
RAD1
RAD1 homolog (S. pombe)
chr4_-_99851766 6.12 ENST00000450253.2
EIF4E
eukaryotic translation initiation factor 4E
chr16_+_81070792 6.11 ENST00000564241.1
ENST00000565237.1
ATMIN
ATM interactor
chr20_+_31407692 5.89 ENST00000375571.5
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chr4_-_99850243 5.87 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E
eukaryotic translation initiation factor 4E
chrX_-_47518527 5.83 ENST00000333119.3
UXT
ubiquitously-expressed, prefoldin-like chaperone
chr10_+_5135981 5.71 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr19_-_46195029 5.66 ENST00000588599.1
ENST00000585392.1
ENST00000590212.1
ENST00000587367.1
ENST00000391932.3
SNRPD2
small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
chr1_-_44818599 5.62 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr17_-_40134339 5.61 ENST00000587727.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr15_-_55562582 5.60 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr12_-_27090896 5.47 ENST00000539625.1
ENST00000538727.1
ASUN
asunder spermatogenesis regulator
chr7_+_120591170 5.31 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr6_+_32812568 5.23 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr3_-_155524049 5.22 ENST00000534941.1
ENST00000340171.2
C3orf33
chromosome 3 open reading frame 33
chr8_-_30585439 5.14 ENST00000221130.5
GSR
glutathione reductase
chr12_+_32832134 4.88 ENST00000452533.2
DNM1L
dynamin 1-like
chr7_+_7606497 4.86 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
MIOS
missing oocyte, meiosis regulator, homolog (Drosophila)
chr12_+_53836339 4.71 ENST00000549135.1
PRR13
proline rich 13
chr22_-_36236265 4.66 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_-_11159887 4.64 ENST00000544779.1
ENST00000304457.7
ENST00000376936.4
EXOSC10
exosome component 10
chr12_+_32832203 4.55 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
DNM1L
dynamin 1-like
chr12_-_75905374 4.34 ENST00000438169.2
ENST00000229214.4
KRR1
KRR1, small subunit (SSU) processome component, homolog (yeast)
chr12_-_71533055 4.26 ENST00000552128.1
TSPAN8
tetraspanin 8
chr16_-_20817753 4.09 ENST00000389345.5
ENST00000300005.3
ENST00000357967.4
ENST00000569729.1
ERI2
ERI1 exoribonuclease family member 2
chr4_-_83769996 3.90 ENST00000511338.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr8_-_74205851 3.88 ENST00000396467.1
RPL7
ribosomal protein L7
chr10_+_47894572 3.69 ENST00000355876.5
FAM21B
family with sequence similarity 21, member B
chr16_+_24549014 3.68 ENST00000564314.1
ENST00000567686.1
RBBP6
retinoblastoma binding protein 6
chr17_+_46908350 3.61 ENST00000258947.3
ENST00000509507.1
ENST00000448105.2
ENST00000570513.1
ENST00000509415.1
ENST00000513119.1
ENST00000416445.2
ENST00000508679.1
ENST00000505071.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr9_-_110540419 3.59 ENST00000398726.3
AL162389.1
Uncharacterized protein
chr3_-_93692781 3.52 ENST00000394236.3
PROS1
protein S (alpha)
chr3_-_165555200 3.49 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr5_-_9630463 3.49 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr11_-_72070206 3.41 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr10_+_47894023 3.38 ENST00000358474.5
FAM21B
family with sequence similarity 21, member B
chr7_-_16872932 3.30 ENST00000419572.2
ENST00000412973.1
AGR2
anterior gradient 2
chr12_-_11062161 3.20 ENST00000390677.2
TAS2R13
taste receptor, type 2, member 13
chr18_-_21017817 3.20 ENST00000542162.1
ENST00000383233.3
ENST00000582336.1
ENST00000450466.2
ENST00000578520.1
ENST00000399707.1
TMEM241
transmembrane protein 241
chr4_+_74606223 3.18 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr3_+_44840679 3.16 ENST00000425755.1
KIF15
kinesin family member 15
chr12_-_68696652 3.10 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr8_-_8318847 3.05 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr8_+_132952112 3.01 ENST00000520362.1
ENST00000519656.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr6_+_26273144 3.01 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr7_+_134464414 2.96 ENST00000361901.2
CALD1
caldesmon 1
chr17_-_46623441 2.93 ENST00000330070.4
HOXB2
homeobox B2
chr5_+_96212185 2.87 ENST00000379904.4
ERAP2
endoplasmic reticulum aminopeptidase 2
chr16_-_18908196 2.86 ENST00000565324.1
ENST00000561947.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr10_-_47239738 2.78 ENST00000413193.2
AGAP10
ArfGAP with GTPase domain, ankyrin repeat and PH domain 10
chr11_+_120255997 2.74 ENST00000532993.1
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr19_+_21265028 2.71 ENST00000291770.7
ZNF714
zinc finger protein 714
chr11_+_67351019 2.70 ENST00000398606.3
GSTP1
glutathione S-transferase pi 1
chr5_+_7654057 2.69 ENST00000537121.1
ADCY2
adenylate cyclase 2 (brain)
chr10_+_8096769 2.69 ENST00000346208.3
GATA3
GATA binding protein 3
chrX_-_23926004 2.67 ENST00000379226.4
ENST00000379220.3
APOO
apolipoprotein O
chr11_-_104972158 2.58 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr5_+_180682720 2.55 ENST00000599439.1
AC008443.1
CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chr4_+_74347400 2.55 ENST00000226355.3
AFM
afamin
chr1_+_33439268 2.54 ENST00000594612.1
FKSG48
FKSG48
chr16_-_70239683 2.52 ENST00000601706.1
AC009060.1
Uncharacterized protein
chr4_+_37962018 2.52 ENST00000504686.1
PTTG2
pituitary tumor-transforming 2
chr8_-_122653630 2.52 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr1_+_76251879 2.36 ENST00000535300.1
ENST00000319942.3
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr6_+_74171301 2.26 ENST00000415954.2
ENST00000498286.1
ENST00000370305.1
ENST00000370300.4
MTO1
mitochondrial tRNA translation optimization 1
chr17_-_9479128 2.19 ENST00000574431.1
STX8
syntaxin 8
chr2_+_131862872 2.16 ENST00000439822.2
PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr3_-_138312971 2.07 ENST00000485115.1
ENST00000484888.1
ENST00000468900.1
ENST00000542237.1
ENST00000481834.1
CEP70
centrosomal protein 70kDa
chr4_-_140223614 2.03 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr12_+_4385230 1.93 ENST00000536537.1
CCND2
cyclin D2
chr3_+_150126101 1.90 ENST00000361875.3
ENST00000361136.2
TSC22D2
TSC22 domain family, member 2
chr3_-_138313161 1.89 ENST00000489254.1
ENST00000474781.1
ENST00000462419.1
ENST00000264982.3
CEP70
centrosomal protein 70kDa
chr3_-_37216055 1.86 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr12_-_102224704 1.78 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr19_-_19932501 1.77 ENST00000540806.2
ENST00000590766.1
ENST00000587452.1
ENST00000545006.1
ENST00000590319.1
ENST00000587461.1
ENST00000450683.2
ENST00000443905.2
ENST00000590274.1
ZNF506
CTC-559E9.4
zinc finger protein 506
CTC-559E9.4
chr4_-_140223670 1.76 ENST00000394228.1
ENST00000539387.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr2_-_188419078 1.73 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr3_+_130569592 1.71 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr3_-_133969673 1.67 ENST00000427044.2
RYK
receptor-like tyrosine kinase
chr2_-_11606275 1.61 ENST00000381525.3
ENST00000362009.4
E2F6
E2F transcription factor 6
chrY_+_26997726 1.60 ENST00000382296.2
DAZ4
deleted in azoospermia 4
chrX_+_71401526 1.58 ENST00000218432.5
ENST00000423432.2
ENST00000373669.2
PIN4
protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
chr4_+_74301880 1.53 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr12_+_21207503 1.49 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr12_+_10460549 1.48 ENST00000543420.1
ENST00000543777.1
KLRD1
killer cell lectin-like receptor subfamily D, member 1
chr8_-_33370607 1.47 ENST00000360742.5
ENST00000523305.1
TTI2
TELO2 interacting protein 2
chr11_+_67351213 1.46 ENST00000398603.1
GSTP1
glutathione S-transferase pi 1
chr6_+_42749759 1.43 ENST00000314073.5
GLTSCR1L
GLTSCR1-like
chr18_-_64271363 1.36 ENST00000262150.2
CDH19
cadherin 19, type 2
chr10_+_48189612 1.36 ENST00000453919.1
AGAP9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr17_-_37607497 1.36 ENST00000394287.3
ENST00000300651.6
MED1
mediator complex subunit 1
chr11_-_327537 1.33 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr2_+_131862900 1.29 ENST00000438882.2
ENST00000538982.1
ENST00000404460.1
PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr12_-_10007448 1.18 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr9_-_36400213 1.17 ENST00000259605.6
ENST00000353739.4
RNF38
ring finger protein 38
chr14_+_39703084 1.13 ENST00000553728.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr3_+_51663407 1.12 ENST00000432863.1
ENST00000296477.3
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr5_+_140560980 1.10 ENST00000361016.2
PCDHB16
protocadherin beta 16
chr10_+_111765562 1.03 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr18_+_616672 0.99 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr10_+_8096631 0.97 ENST00000379328.3
GATA3
GATA binding protein 3
chr19_+_13135386 0.96 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr3_-_120365866 0.95 ENST00000475447.2
HGD
homogentisate 1,2-dioxygenase
chrX_+_115301975 0.94 ENST00000371906.4
AGTR2
angiotensin II receptor, type 2
chr10_+_5005598 0.89 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr17_-_18266797 0.89 ENST00000316694.3
ENST00000539052.1
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr22_-_36236623 0.87 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr10_+_5005445 0.81 ENST00000380872.4
AKR1C1
aldo-keto reductase family 1, member C1
chr19_-_29704448 0.79 ENST00000304863.4
UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr1_+_170633047 0.77 ENST00000239461.6
ENST00000497230.2
PRRX1
paired related homeobox 1
chr12_+_26164645 0.77 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr6_-_49712123 0.75 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr1_+_210501589 0.74 ENST00000413764.2
ENST00000541565.1
HHAT
hedgehog acyltransferase
chr17_-_39041479 0.73 ENST00000167588.3
KRT20
keratin 20
chr7_-_38289173 0.73 ENST00000436911.2
TRGC2
T cell receptor gamma constant 2
chr15_-_85197501 0.72 ENST00000434634.2
WDR73
WD repeat domain 73
chr19_+_45281118 0.71 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr3_+_179065474 0.68 ENST00000471841.1
ENST00000280653.7
MFN1
mitofusin 1
chr2_+_172544011 0.66 ENST00000508530.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr12_+_10460417 0.65 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
KLRD1
killer cell lectin-like receptor subfamily D, member 1
chr5_+_35856951 0.63 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr3_+_160394940 0.61 ENST00000320767.2
ARL14
ADP-ribosylation factor-like 14
chr3_-_126327398 0.56 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr2_+_172543919 0.54 ENST00000452242.1
ENST00000340296.4
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr4_-_70518941 0.53 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr18_+_616711 0.53 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr19_-_44079611 0.51 ENST00000594107.1
ENST00000543982.1
XRCC1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr2_+_191334212 0.50 ENST00000444317.1
ENST00000535751.1
MFSD6
major facilitator superfamily domain containing 6
chr1_+_32608566 0.47 ENST00000545542.1
KPNA6
karyopherin alpha 6 (importin alpha 7)
chrX_+_65382381 0.46 ENST00000519389.1
HEPH
hephaestin
chr18_+_39535152 0.43 ENST00000262039.4
ENST00000398870.3
ENST00000586545.1
PIK3C3
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr4_+_70796784 0.43 ENST00000246891.4
ENST00000444405.3
CSN1S1
casein alpha s1
chr17_+_32597232 0.39 ENST00000378569.2
ENST00000200307.4
ENST00000394627.1
ENST00000394630.3
CCL7
chemokine (C-C motif) ligand 7
chr4_+_88532028 0.36 ENST00000282478.7
DSPP
dentin sialophosphoprotein
chr21_-_30391636 0.27 ENST00000493196.1
RWDD2B
RWD domain containing 2B
chr5_+_67586465 0.27 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_+_133657461 0.26 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
ZNF140
zinc finger protein 140
chr2_+_172543967 0.25 ENST00000534253.2
ENST00000263811.4
ENST00000397119.3
ENST00000410079.3
ENST00000438879.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr13_+_77564795 0.23 ENST00000377453.3
CLN5
ceroid-lipofuscinosis, neuronal 5
chr6_+_25963020 0.23 ENST00000357085.3
TRIM38
tripartite motif containing 38
chr10_+_52094298 0.14 ENST00000595931.1
AC069547.1
HCG1745369; PRO3073; Uncharacterized protein
chr21_+_37692481 0.12 ENST00000400485.1
MORC3
MORC family CW-type zinc finger 3
chr15_-_50406680 0.11 ENST00000559829.1
ATP8B4
ATPase, class I, type 8B, member 4
chr19_-_14992264 0.10 ENST00000327462.2
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr9_+_79074068 0.03 ENST00000444201.2
ENST00000376730.4
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB16

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 23.4 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
3.1 9.4 GO:0090149 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
2.4 14.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
2.2 11.0 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
2.1 16.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
2.0 5.9 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
1.9 5.7 GO:0016095 polyprenol catabolic process(GO:0016095)
1.6 6.2 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
1.5 4.6 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
1.5 7.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.2 3.7 GO:1901536 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
1.2 3.5 GO:0014016 neuroblast differentiation(GO:0014016)
1.1 8.0 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
1.1 6.5 GO:1901029 adenine transport(GO:0015853) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
1.1 3.2 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
1.1 6.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.0 4.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
1.0 2.9 GO:0021569 rhombomere 3 development(GO:0021569)
0.9 5.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.9 7.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.6 2.6 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.6 3.6 GO:1901098 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.6 26.5 GO:0045143 homologous chromosome segregation(GO:0045143) negative regulation of mitotic sister chromatid separation(GO:2000816)
0.5 3.3 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.5 2.5 GO:0070295 renal water absorption(GO:0070295)
0.5 1.4 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.4 21.5 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.4 1.7 GO:0061643 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.4 5.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.3 1.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.3 7.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 3.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3 6.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 0.9 GO:1904482 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.3 2.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.3 1.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.3 1.7 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.3 6.1 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.3 2.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.2 6.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 3.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 5.8 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.2 7.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 2.7 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 2.9 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 3.5 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 3.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 5.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 1.4 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 4.9 GO:0034629 cellular protein complex localization(GO:0034629)
0.2 0.8 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.9 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.5 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 4.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.1 1.9 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 1.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 5.1 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 4.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.8 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 2.7 GO:0042407 cristae formation(GO:0042407)
0.1 4.3 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 1.6 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 2.2 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 0.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 0.6 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 2.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 7.9 GO:0007224 smoothened signaling pathway(GO:0007224)
0.1 2.5 GO:0051180 vitamin transport(GO:0051180)
0.1 5.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.1 3.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 3.7 GO:0061053 somite development(GO:0061053)
0.0 1.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 5.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 3.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 2.1 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 6.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.6 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 3.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 4.3 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
0.0 1.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 23.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.8 7.0 GO:0000811 GINS complex(GO:0000811)
1.6 6.2 GO:0030896 checkpoint clamp complex(GO:0030896)
1.4 4.2 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
1.3 5.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.2 11.0 GO:0005638 lamin filament(GO:0005638)
1.2 7.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.2 14.2 GO:0033093 Weibel-Palade body(GO:0033093)
1.1 12.0 GO:0033391 chromatoid body(GO:0033391)
1.1 7.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.1 6.5 GO:0071817 MMXD complex(GO:0071817)
1.1 3.2 GO:0005873 plus-end kinesin complex(GO:0005873)
1.0 5.9 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.7 5.7 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.7 4.9 GO:0061700 GATOR2 complex(GO:0061700)
0.7 5.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.6 6.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.6 2.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.5 2.6 GO:0097179 protease inhibitor complex(GO:0097179)
0.5 7.2 GO:0097227 sperm annulus(GO:0097227)
0.4 4.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.4 2.7 GO:0061617 MICOS complex(GO:0061617)
0.3 1.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 3.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 5.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 3.0 GO:0030478 actin cap(GO:0030478)
0.2 3.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.4 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 4.3 GO:0032040 small-subunit processome(GO:0032040)
0.1 2.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 9.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 3.6 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.5 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.1 0.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 6.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.7 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 3.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 8.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.2 GO:0031201 SNARE complex(GO:0031201)
0.0 2.5 GO:0072562 blood microparticle(GO:0072562)
0.0 1.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 2.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 16.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 3.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 3.1 GO:0005814 centriole(GO:0005814)
0.0 7.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.2 GO:0036126 sperm flagellum(GO:0036126)
0.0 1.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.0 GO:0000794 condensed nuclear chromosome(GO:0000794)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.4 GO:0047718 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
1.7 5.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
1.6 6.5 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
1.5 16.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.5 12.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
1.1 3.2 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
1.0 7.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.0 6.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
1.0 23.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
1.0 8.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.9 7.6 GO:0004111 creatine kinase activity(GO:0004111)
0.9 10.6 GO:0089720 caspase binding(GO:0089720)
0.9 3.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.8 2.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.8 4.2 GO:0070026 nitric oxide binding(GO:0070026)
0.7 6.8 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.6 2.5 GO:0008431 vitamin E binding(GO:0008431)
0.6 3.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.6 6.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.5 14.2 GO:0031489 myosin V binding(GO:0031489)
0.5 7.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.5 6.7 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.5 2.4 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.5 9.4 GO:0051400 BH domain binding(GO:0051400)
0.5 1.4 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.4 2.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.3 1.7 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.3 22.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 6.1 GO:0070840 dynein complex binding(GO:0070840)
0.2 6.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 5.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.6 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 2.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 3.3 GO:0002162 dystroglycan binding(GO:0002162)
0.2 0.9 GO:0070905 serine binding(GO:0070905)
0.2 5.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 2.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 5.6 GO:0001671 ATPase activator activity(GO:0001671)
0.2 4.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 5.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 2.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.8 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 3.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.6 GO:0008494 translation activator activity(GO:0008494)
0.1 4.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 5.3 GO:0035064 methylated histone binding(GO:0035064)
0.1 3.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 3.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 5.6 GO:0004527 exonuclease activity(GO:0004527)
0.1 1.9 GO:0030275 LRR domain binding(GO:0030275)
0.1 2.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.9 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 1.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 3.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 3.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 9.4 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.8 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 1.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.7 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 4.3 GO:0005178 integrin binding(GO:0005178)
0.0 5.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 3.1 GO:0008017 microtubule binding(GO:0008017)
0.0 0.4 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 5.5 GO:0005525 GTP binding(GO:0005525)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 1.4 GO:0030414 peptidase inhibitor activity(GO:0030414)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 23.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 12.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 13.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 6.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 5.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 7.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 13.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 3.7 PID IL27 PATHWAY IL27-mediated signaling events
0.1 2.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 7.9 PID E2F PATHWAY E2F transcription factor network
0.1 7.2 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 5.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 23.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.6 12.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.5 14.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.5 7.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.5 7.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.4 7.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 29.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.2 3.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 14.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 6.2 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.2 2.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 5.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 11.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 11.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 3.2 REACTOME KINESINS Genes involved in Kinesins
0.1 4.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 3.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 5.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 9.4 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.1 2.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 3.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.6 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 1.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 3.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 6.7 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 1.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors