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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for ZBTB4

Z-value: 0.18

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Transcription factors associated with ZBTB4

Gene Symbol Gene ID Gene Info
ZBTB4
ENSG00000174282.7 zinc finger and BTB domain containing 4

Activity profile of ZBTB4 motif

Sorted Z-values of ZBTB4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_169075554 20.88 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr14_-_69445968 19.21 ENST00000438964.2
ACTN1
actinin, alpha 1
chr14_-_69445793 18.77 ENST00000538545.2
ENST00000394419.4
ACTN1
actinin, alpha 1
chr14_-_69446034 16.09 ENST00000193403.6
ACTN1
actinin, alpha 1
chr8_-_27468842 11.91 ENST00000523500.1
CLU
clusterin
chr3_-_57583185 11.53 ENST00000463880.1
ARF4
ADP-ribosylation factor 4
chr15_-_77363513 11.36 ENST00000267970.4
TSPAN3
tetraspanin 3
chr19_+_36631867 10.91 ENST00000588780.1
CAPNS1
calpain, small subunit 1
chr19_+_47104553 10.39 ENST00000598871.1
ENST00000594523.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr11_+_86511569 9.86 ENST00000441050.1
PRSS23
protease, serine, 23
chr2_+_192109911 9.58 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
MYO1B
myosin IB
chr16_-_87903079 9.06 ENST00000261622.4
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr3_-_57583052 8.98 ENST00000496292.1
ENST00000489843.1
ARF4
ADP-ribosylation factor 4
chr19_+_47104493 8.90 ENST00000291295.9
ENST00000597743.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr3_-_57583130 8.89 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr19_-_10530784 8.70 ENST00000593124.1
CDC37
cell division cycle 37
chrX_-_68385354 8.40 ENST00000361478.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr17_-_15165854 8.35 ENST00000395936.1
ENST00000395938.2
PMP22
peripheral myelin protein 22
chrX_-_68385274 8.18 ENST00000374584.3
ENST00000590146.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr8_-_27468945 8.13 ENST00000405140.3
CLU
clusterin
chr2_+_192110199 7.98 ENST00000304164.4
MYO1B
myosin IB
chr8_-_27469196 7.96 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr19_-_20748541 7.75 ENST00000427401.4
ENST00000594419.1
ZNF737
zinc finger protein 737
chr14_-_23822080 7.53 ENST00000397267.1
ENST00000354772.3
SLC22A17
solute carrier family 22, member 17
chr19_+_39138320 7.27 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
ACTN4
actinin, alpha 4
chr19_+_50354430 6.94 ENST00000599732.1
PTOV1
prostate tumor overexpressed 1
chr15_+_42697065 6.18 ENST00000565559.1
CAPN3
calpain 3, (p94)
chr5_-_146889619 6.15 ENST00000343218.5
DPYSL3
dihydropyrimidinase-like 3
chr1_-_165738072 6.13 ENST00000481278.1
TMCO1
transmembrane and coiled-coil domains 1
chr15_+_42696954 5.95 ENST00000337571.4
ENST00000569136.1
CAPN3
calpain 3, (p94)
chr17_-_48943706 5.93 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chr1_-_19811132 5.93 ENST00000433834.1
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr14_-_45603657 5.88 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr1_-_108742957 5.71 ENST00000565488.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr15_+_25200108 5.65 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNURF
SNRPN
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr16_-_11370330 5.58 ENST00000241808.4
ENST00000435245.2
PRM2
protamine 2
chr15_+_25200074 5.42 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr9_-_93405352 5.37 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr15_+_42696992 5.24 ENST00000561817.1
CAPN3
calpain 3, (p94)
chr1_-_36615051 5.22 ENST00000373163.1
TRAPPC3
trafficking protein particle complex 3
chr6_-_49430886 5.20 ENST00000274813.3
MUT
methylmalonyl CoA mutase
chr15_+_42697018 5.16 ENST00000397204.4
CAPN3
calpain 3, (p94)
chr10_+_105036909 5.01 ENST00000369849.4
INA
internexin neuronal intermediate filament protein, alpha
chr1_-_32403370 5.00 ENST00000534796.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr1_-_36615065 4.91 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chr2_+_182756701 4.87 ENST00000409001.1
SSFA2
sperm specific antigen 2
chr10_+_121485588 4.81 ENST00000361976.2
ENST00000369083.3
INPP5F
inositol polyphosphate-5-phosphatase F
chr2_-_10952832 4.68 ENST00000540494.1
PDIA6
protein disulfide isomerase family A, member 6
chr22_+_50312379 4.66 ENST00000407217.3
ENST00000403427.3
CRELD2
cysteine-rich with EGF-like domains 2
chr12_+_112204691 4.57 ENST00000416293.3
ENST00000261733.2
ALDH2
aldehyde dehydrogenase 2 family (mitochondrial)
chr9_-_88897426 4.52 ENST00000375991.4
ENST00000326094.4
ISCA1
iron-sulfur cluster assembly 1
chr17_-_9479128 4.48 ENST00000574431.1
STX8
syntaxin 8
chr12_-_49525175 4.44 ENST00000336023.5
ENST00000550367.1
ENST00000552984.1
ENST00000547476.1
TUBA1B
tubulin, alpha 1b
chr19_+_39138271 4.39 ENST00000252699.2
ACTN4
actinin, alpha 4
chr10_-_32345305 4.30 ENST00000302418.4
KIF5B
kinesin family member 5B
chr17_+_7487146 4.17 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr1_+_166808692 4.17 ENST00000367876.4
POGK
pogo transposable element with KRAB domain
chr14_+_85996471 4.17 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr22_-_43411106 4.15 ENST00000453643.1
ENST00000263246.3
ENST00000337959.4
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr11_-_72385437 4.12 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr13_-_24007815 4.06 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr2_-_10952922 3.88 ENST00000272227.3
PDIA6
protein disulfide isomerase family A, member 6
chr1_+_65886262 3.84 ENST00000371065.4
LEPROT
leptin receptor overlapping transcript
chr8_-_74205851 3.67 ENST00000396467.1
RPL7
ribosomal protein L7
chr17_-_79827808 3.63 ENST00000580685.1
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr11_+_62104897 3.62 ENST00000415229.2
ENST00000535727.1
ENST00000301776.5
ASRGL1
asparaginase like 1
chr20_-_36793774 3.60 ENST00000361475.2
TGM2
transglutaminase 2
chrX_-_71526813 3.58 ENST00000246139.5
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr21_-_38445470 3.57 ENST00000399098.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr1_-_165738085 3.53 ENST00000464650.1
ENST00000392129.6
TMCO1
transmembrane and coiled-coil domains 1
chr8_-_29208183 3.45 ENST00000240100.2
DUSP4
dual specificity phosphatase 4
chr3_-_167452614 3.41 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
PDCD10
programmed cell death 10
chr8_+_11660120 3.39 ENST00000220584.4
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr11_-_61735029 3.38 ENST00000526640.1
FTH1
ferritin, heavy polypeptide 1
chr19_+_20959142 3.35 ENST00000344519.8
ZNF66
zinc finger protein 66
chr3_-_167452703 3.35 ENST00000497056.2
ENST00000473645.2
PDCD10
programmed cell death 10
chr8_-_71581377 3.27 ENST00000276590.4
ENST00000522447.1
LACTB2
lactamase, beta 2
chr14_-_74551096 3.23 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr8_+_94929077 3.10 ENST00000297598.4
ENST00000520614.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr22_+_50312316 3.01 ENST00000328268.4
CRELD2
cysteine-rich with EGF-like domains 2
chr1_-_154946825 3.00 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr21_-_38445011 2.99 ENST00000464265.1
ENST00000399102.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr19_+_39421556 2.98 ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr19_+_41770349 2.97 ENST00000602130.1
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr19_+_36024310 2.89 ENST00000222286.4
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr9_-_88896977 2.83 ENST00000311534.6
ISCA1
iron-sulfur cluster assembly 1
chr2_-_207024233 2.77 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr7_-_44613494 2.75 ENST00000431640.1
ENST00000258772.5
DDX56
DEAD (Asp-Glu-Ala-Asp) box helicase 56
chr10_+_123922941 2.75 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr11_+_62623512 2.70 ENST00000377892.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr11_+_62623544 2.65 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr1_+_154947148 2.63 ENST00000368436.1
ENST00000308987.5
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr14_-_24701539 2.54 ENST00000534348.1
ENST00000524927.1
ENST00000250495.5
NEDD8-MDP1
NEDD8
NEDD8-MDP1 readthrough
neural precursor cell expressed, developmentally down-regulated 8
chr4_-_7069760 2.53 ENST00000264954.4
GRPEL1
GrpE-like 1, mitochondrial (E. coli)
chr14_-_25479811 2.52 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr6_+_49431073 2.46 ENST00000335783.3
CENPQ
centromere protein Q
chr4_+_4388805 2.39 ENST00000504171.1
NSG1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr19_+_17830051 2.39 ENST00000594625.1
ENST00000324096.4
ENST00000600186.1
ENST00000597735.1
MAP1S
microtubule-associated protein 1S
chr1_+_154947126 2.34 ENST00000368439.1
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr6_-_13711773 2.22 ENST00000011619.3
RANBP9
RAN binding protein 9
chr2_+_201936458 2.18 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr1_-_33283754 2.06 ENST00000373477.4
YARS
tyrosyl-tRNA synthetase
chr17_+_45727204 2.06 ENST00000290158.4
KPNB1
karyopherin (importin) beta 1
chr6_-_136847610 2.05 ENST00000454590.1
ENST00000432797.2
MAP7
microtubule-associated protein 7
chr14_+_24702099 2.00 ENST00000420554.2
GMPR2
guanosine monophosphate reductase 2
chr19_-_17356697 1.94 ENST00000291442.3
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr11_-_46940074 1.92 ENST00000378623.1
ENST00000534404.1
LRP4
low density lipoprotein receptor-related protein 4
chr16_-_30538079 1.92 ENST00000562803.1
ZNF768
zinc finger protein 768
chr19_-_41903161 1.88 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr8_+_94929110 1.86 ENST00000520728.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr8_+_94929168 1.85 ENST00000518107.1
ENST00000396200.3
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr3_-_119813264 1.85 ENST00000264235.8
GSK3B
glycogen synthase kinase 3 beta
chr1_+_10534944 1.82 ENST00000356607.4
ENST00000538836.1
ENST00000491661.2
PEX14
peroxisomal biogenesis factor 14
chr1_-_151299842 1.79 ENST00000438243.2
ENST00000489223.2
ENST00000368873.1
ENST00000430800.1
ENST00000368872.1
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr14_+_24702073 1.75 ENST00000399440.2
GMPR2
guanosine monophosphate reductase 2
chr5_-_115177247 1.69 ENST00000500945.2
ATG12
autophagy related 12
chr14_+_24701819 1.69 ENST00000560139.1
ENST00000559910.1
GMPR2
guanosine monophosphate reductase 2
chr19_-_39881777 1.68 ENST00000595564.1
ENST00000221265.3
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr11_-_64546202 1.61 ENST00000377390.3
ENST00000227503.9
ENST00000377394.3
ENST00000422298.2
ENST00000334944.5
SF1
splicing factor 1
chr10_+_35416223 1.58 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr14_+_24701628 1.55 ENST00000355299.4
ENST00000559836.1
GMPR2
guanosine monophosphate reductase 2
chr17_-_5389477 1.46 ENST00000572834.1
ENST00000570848.1
ENST00000571971.1
ENST00000158771.4
DERL2
derlin 2
chr3_+_19988566 1.43 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr14_-_35099315 1.43 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
SNX6
sorting nexin 6
chr1_-_67896095 1.43 ENST00000370994.4
SERBP1
SERPINE1 mRNA binding protein 1
chr5_-_137090028 1.39 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr20_-_36793663 1.38 ENST00000536701.1
ENST00000536724.1
TGM2
transglutaminase 2
chr3_+_19988885 1.27 ENST00000422242.1
RAB5A
RAB5A, member RAS oncogene family
chr3_+_148583043 1.25 ENST00000296046.3
CPA3
carboxypeptidase A3 (mast cell)
chr19_+_10217364 1.21 ENST00000430370.1
PPAN
peter pan homolog (Drosophila)
chr9_-_128246769 1.18 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr7_+_102937869 1.17 ENST00000249269.4
ENST00000428154.1
ENST00000420236.2
PMPCB
peptidase (mitochondrial processing) beta
chr1_-_67896069 1.16 ENST00000370995.2
ENST00000361219.6
SERBP1
SERPINE1 mRNA binding protein 1
chr19_+_6135646 1.06 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr10_+_17851362 0.87 ENST00000331429.2
ENST00000457317.1
MRC1L1
cDNA FLJ56855, highly similar to Macrophage mannose receptor 1
chr12_-_46766577 0.81 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr14_+_23305760 0.80 ENST00000311852.6
MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr13_+_24734880 0.74 ENST00000382095.4
SPATA13
spermatogenesis associated 13
chr4_-_156297949 0.70 ENST00000515654.1
MAP9
microtubule-associated protein 9
chr1_+_43148625 0.66 ENST00000436427.1
YBX1
Y box binding protein 1
chr17_-_19265855 0.65 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9D1
B9 protein domain 1
chr9_-_131709858 0.61 ENST00000372586.3
DOLK
dolichol kinase
chr13_-_33780133 0.58 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr1_+_43148059 0.54 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr4_-_156298028 0.45 ENST00000433024.1
ENST00000379248.2
MAP9
microtubule-associated protein 9
chr16_-_22385901 0.42 ENST00000268383.2
CDR2
cerebellar degeneration-related protein 2, 62kDa
chr2_+_152266392 0.42 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
RIF1
RAP1 interacting factor homolog (yeast)
chrX_+_100075368 0.37 ENST00000415585.2
ENST00000372972.2
ENST00000413437.1
CSTF2
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
chr1_-_67896009 0.37 ENST00000370990.5
SERBP1
SERPINE1 mRNA binding protein 1
chr15_-_44116873 0.33 ENST00000267812.3
MFAP1
microfibrillar-associated protein 1
chr1_+_196788887 0.28 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr1_+_196912902 0.22 ENST00000476712.2
ENST00000367415.5
CFHR2
complement factor H-related 2
chr1_-_156786530 0.19 ENST00000368198.3
SH2D2A
SH2 domain containing 2A
chr21_+_34638656 0.19 ENST00000290200.2
IL10RB
interleukin 10 receptor, beta
chr19_-_19144243 0.17 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SUGP2
SURP and G patch domain containing 2
chrX_-_152736013 0.17 ENST00000330912.2
ENST00000338525.2
ENST00000334497.2
ENST00000370232.1
ENST00000370212.3
ENST00000370211.4
TREX2
HAUS7
three prime repair exonuclease 2
HAUS augmin-like complex, subunit 7
chr1_+_110163709 0.16 ENST00000369840.2
ENST00000527846.1
AMPD2
adenosine monophosphate deaminase 2
chr19_-_39881669 0.15 ENST00000221266.7
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chrX_+_135579670 0.07 ENST00000218364.4
HTATSF1
HIV-1 Tat specific factor 1
chr5_-_150948414 0.05 ENST00000261800.5
FAT2
FAT atypical cadherin 2
chr19_-_9006766 0.01 ENST00000599436.1
MUC16
mucin 16, cell surface associated
chr6_-_74231444 0.00 ENST00000331523.2
ENST00000356303.2
EEF1A1
eukaryotic translation elongation factor 1 alpha 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 20.9 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
4.7 28.0 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
3.9 11.7 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
3.8 22.5 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
3.4 54.1 GO:0051639 actin filament network formation(GO:0051639)
2.7 29.4 GO:0031584 activation of phospholipase D activity(GO:0031584) apical protein localization(GO:0045176)
1.7 5.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.7 5.0 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
1.5 7.5 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.4 4.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
1.4 6.8 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
1.3 3.8 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
1.2 7.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
1.2 5.9 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
1.1 5.3 GO:0060356 leucine import(GO:0060356)
1.0 11.5 GO:0006983 ER overload response(GO:0006983)
0.9 4.3 GO:0035617 stress granule disassembly(GO:0035617)
0.7 5.7 GO:0015866 ADP transport(GO:0015866)
0.7 4.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.7 3.4 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.6 3.2 GO:0006574 valine catabolic process(GO:0006574)
0.6 10.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.6 1.9 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.6 1.9 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.6 1.8 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.6 3.6 GO:0071105 response to interleukin-11(GO:0071105)
0.5 4.1 GO:0070836 caveola assembly(GO:0070836)
0.5 2.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.5 6.1 GO:0051764 actin crosslink formation(GO:0051764)
0.5 5.0 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.5 3.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.5 4.6 GO:0006069 ethanol oxidation(GO:0006069)
0.5 3.6 GO:0006528 asparagine metabolic process(GO:0006528)
0.5 2.7 GO:0051036 regulation of endosome size(GO:0051036)
0.4 4.8 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.4 5.9 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.4 8.3 GO:0032060 bleb assembly(GO:0032060)
0.4 8.7 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.3 6.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.3 1.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.3 3.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3 2.4 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.3 9.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.3 4.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.3 2.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.3 2.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.3 7.2 GO:0043101 purine-containing compound salvage(GO:0043101)
0.3 4.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 1.5 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 1.4 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.2 1.8 GO:0016584 nucleosome positioning(GO:0016584)
0.2 1.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2 2.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 1.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 0.8 GO:1990834 response to odorant(GO:1990834)
0.2 2.5 GO:0045116 protein neddylation(GO:0045116)
0.2 8.6 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 4.5 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 13.2 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 5.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 1.0 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 10.1 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 5.0 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 2.9 GO:0045821 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.1 3.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 10.9 GO:0070268 cornification(GO:0070268)
0.1 1.9 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 3.0 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 2.5 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 1.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 1.2 GO:0002003 angiotensin maturation(GO:0002003)
0.1 1.7 GO:0044804 nucleophagy(GO:0044804)
0.1 3.8 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 2.2 GO:0007020 microtubule nucleation(GO:0007020)
0.1 4.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.3 GO:0030261 chromosome condensation(GO:0030261)
0.1 1.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 2.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 3.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 3.0 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0 0.5 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 3.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 14.0 GO:0016567 protein ubiquitination(GO:0016567)
0.0 2.7 GO:0021987 cerebral cortex development(GO:0021987)
0.0 4.6 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 7.6 GO:0043687 post-translational protein modification(GO:0043687)
0.0 1.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.6 GO:0060563 neuroepithelial cell differentiation(GO:0060563)
0.0 2.1 GO:0072659 protein localization to plasma membrane(GO:0072659)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 54.1 GO:0005916 fascia adherens(GO:0005916)
1.8 28.0 GO:0097418 neurofibrillary tangle(GO:0097418)
1.2 7.0 GO:1902560 GMP reductase complex(GO:1902560)
1.0 20.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.8 5.9 GO:0071203 WASH complex(GO:0071203)
0.8 10.1 GO:0030008 TRAPP complex(GO:0030008)
0.8 3.4 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.7 6.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.7 11.1 GO:0005687 U4 snRNP(GO:0005687)
0.6 2.5 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.6 4.1 GO:0070852 cell body fiber(GO:0070852)
0.6 2.8 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.5 3.0 GO:0070435 Shc-EGFR complex(GO:0070435)
0.5 11.7 GO:0031143 pseudopodium(GO:0031143)
0.5 8.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.4 5.0 GO:0005883 neurofilament(GO:0005883)
0.4 2.1 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.3 5.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.3 2.7 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.3 4.3 GO:0035253 ciliary rootlet(GO:0035253)
0.3 2.4 GO:0098845 postsynaptic endosome(GO:0098845)
0.3 1.4 GO:0097422 tubular endosome(GO:0097422)
0.3 1.7 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.3 20.8 GO:0030315 T-tubule(GO:0030315)
0.3 8.3 GO:0043218 compact myelin(GO:0043218)
0.3 0.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 1.5 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.2 1.8 GO:1990909 Wnt signalosome(GO:1990909)
0.2 1.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 17.6 GO:0016459 myosin complex(GO:0016459)
0.2 1.9 GO:0016600 flotillin complex(GO:0016600)
0.2 1.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 1.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.2 29.4 GO:0043197 dendritic spine(GO:0043197)
0.1 6.1 GO:0031941 filamentous actin(GO:0031941)
0.1 1.0 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 2.5 GO:0000145 exocyst(GO:0000145)
0.1 19.2 GO:0000922 spindle pole(GO:0000922)
0.1 3.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 2.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 5.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 13.4 GO:0055037 recycling endosome(GO:0055037)
0.1 1.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 4.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.4 GO:0001940 male pronucleus(GO:0001940)
0.1 4.3 GO:0000786 nucleosome(GO:0000786)
0.1 8.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.2 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 4.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 7.5 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 5.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 3.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 14.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 4.2 GO:0005875 microtubule associated complex(GO:0005875)
0.0 9.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 7.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.6 GO:0005840 ribosome(GO:0005840)
0.0 2.4 GO:0005819 spindle(GO:0005819)
0.0 2.6 GO:0071944 cell periphery(GO:0071944)
0.0 3.7 GO:0005769 early endosome(GO:0005769)
0.0 7.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.8 GO:0005903 brush border(GO:0005903)
0.0 3.2 GO:0010008 endosome membrane(GO:0010008)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 54.1 GO:0017166 vinculin binding(GO:0017166)
1.8 43.4 GO:0031402 sodium ion binding(GO:0031402)
1.4 28.0 GO:0051787 misfolded protein binding(GO:0051787)
1.3 5.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
1.2 3.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
1.2 7.0 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
1.1 3.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.1 6.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.1 29.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.1 4.3 GO:0099609 microtubule lateral binding(GO:0099609)
1.0 4.8 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.8 3.4 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.8 6.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.8 17.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.7 2.9 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.7 5.7 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.7 5.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.7 4.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.7 6.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.6 5.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5 5.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.5 3.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.5 5.2 GO:0031419 cobalamin binding(GO:0031419)
0.5 5.6 GO:0046870 cadmium ion binding(GO:0046870)
0.4 3.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 4.6 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.4 8.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.4 4.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.4 7.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.4 3.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 10.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 1.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.3 9.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.3 1.7 GO:0019776 Atg8 ligase activity(GO:0019776)
0.3 11.7 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.3 2.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 4.1 GO:0045499 chemorepellent activity(GO:0045499)
0.3 3.6 GO:0050693 LBD domain binding(GO:0050693)
0.2 5.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 4.1 GO:0070628 proteasome binding(GO:0070628)
0.2 10.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 5.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 2.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 10.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 1.9 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 1.4 GO:0034452 dynactin binding(GO:0034452)
0.1 3.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 2.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 7.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 1.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 4.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 2.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 9.7 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.6 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 16.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 9.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 3.3 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 2.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 2.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 8.3 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 12.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 4.9 GO:0051015 actin filament binding(GO:0051015)
0.0 1.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 2.7 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 6.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 3.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 2.7 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 8.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 49.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.3 9.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 11.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.2 31.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 32.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.2 10.5 PID LKB1 PATHWAY LKB1 signaling events
0.2 5.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 15.3 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 3.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 4.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 4.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 5.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 5.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 4.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 6.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 3.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 6.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 65.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
1.0 19.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.8 35.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.6 4.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.4 6.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 11.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.3 5.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 7.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 6.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 6.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 3.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 1.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 28.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 4.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 4.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 4.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 8.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 3.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 4.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 5.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 2.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 3.4 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 16.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 3.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 4.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 2.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 2.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.2 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 3.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 3.7 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 1.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production