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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for ZBTB49

Z-value: 0.75

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Transcription factors associated with ZBTB49

Gene Symbol Gene ID Gene Info
ZBTB49
ENSG00000168826.11 zinc finger and BTB domain containing 49

Activity profile of ZBTB49 motif

Sorted Z-values of ZBTB49 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_2950642 19.45 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chrX_-_151903184 13.49 ENST00000357916.4
ENST00000393869.3
MAGEA12
melanoma antigen family A, 12
chr20_+_1115821 13.25 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr10_+_94352956 13.11 ENST00000260731.3
KIF11
kinesin family member 11
chr12_+_53835383 11.44 ENST00000429243.2
PRR13
proline rich 13
chrX_-_151903101 10.76 ENST00000393900.3
MAGEA12
melanoma antigen family A, 12
chr12_+_53835539 10.52 ENST00000547368.1
ENST00000379786.4
ENST00000551945.1
PRR13
proline rich 13
chr21_-_26979786 9.26 ENST00000419219.1
ENST00000352957.4
ENST00000307301.7
MRPL39
mitochondrial ribosomal protein L39
chr14_+_35591928 9.09 ENST00000605870.1
ENST00000557404.3
KIAA0391
KIAA0391
chr19_+_18669809 8.70 ENST00000602094.1
KXD1
KxDL motif containing 1
chr11_+_4116054 8.51 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr22_-_19166343 8.21 ENST00000215882.5
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr11_+_4116005 8.13 ENST00000300738.5
RRM1
ribonucleotide reductase M1
chr7_-_44613494 7.97 ENST00000431640.1
ENST00000258772.5
DDX56
DEAD (Asp-Glu-Ala-Asp) box helicase 56
chr1_+_26869597 7.41 ENST00000530003.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chrX_+_64887512 7.40 ENST00000360270.5
MSN
moesin
chr14_+_35591858 7.27 ENST00000603544.1
KIAA0391
KIAA0391
chr14_+_35591735 6.81 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
KIAA0391
KIAA0391
chr7_+_99006232 6.69 ENST00000403633.2
BUD31
BUD31 homolog (S. cerevisiae)
chr12_+_104324112 6.65 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr14_-_35591433 6.26 ENST00000261475.5
ENST00000555644.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr12_+_53835508 5.68 ENST00000551003.1
ENST00000549068.1
ENST00000549740.1
ENST00000546581.1
ENST00000549581.1
ENST00000541275.1
PRR13
PCBP2
proline rich 13
poly(rC) binding protein 2
chr19_-_59070239 5.64 ENST00000595957.1
ENST00000253023.3
UBE2M
ubiquitin-conjugating enzyme E2M
chr22_+_21996549 5.58 ENST00000248958.4
SDF2L1
stromal cell-derived factor 2-like 1
chr20_-_32700075 5.44 ENST00000374980.2
EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr8_-_99129338 5.30 ENST00000520507.1
HRSP12
heat-responsive protein 12
chr6_-_159240415 5.15 ENST00000367075.3
EZR
ezrin
chr16_-_28621353 5.13 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chrX_+_151903253 5.11 ENST00000452779.2
ENST00000370291.2
CSAG1
chondrosarcoma associated gene 1
chr1_+_79115503 5.05 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr3_+_52232102 4.27 ENST00000469224.1
ENST00000394965.2
ENST00000310271.2
ENST00000484952.1
ALAS1
aminolevulinate, delta-, synthase 1
chr11_+_117857063 4.13 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
IL10RA
interleukin 10 receptor, alpha
chr5_+_154237778 4.00 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
CNOT8
CCR4-NOT transcription complex, subunit 8
chr5_+_154238042 3.96 ENST00000519211.1
ENST00000522458.1
ENST00000519903.1
ENST00000521450.1
ENST00000403027.2
CNOT8
CCR4-NOT transcription complex, subunit 8
chr8_+_95653302 3.95 ENST00000423620.2
ENST00000433389.2
ESRP1
epithelial splicing regulatory protein 1
chr15_-_55489097 3.92 ENST00000260443.4
RSL24D1
ribosomal L24 domain containing 1
chr3_+_39424828 3.89 ENST00000273158.4
ENST00000431510.1
SLC25A38
solute carrier family 25, member 38
chrX_+_101854096 3.80 ENST00000246174.2
ENST00000537008.1
ENST00000541409.1
ARMCX5
armadillo repeat containing, X-linked 5
chr5_+_154238096 3.73 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
CNOT8
CCR4-NOT transcription complex, subunit 8
chr22_-_29196030 3.65 ENST00000405219.3
XBP1
X-box binding protein 1
chr17_+_80009741 3.64 ENST00000578552.1
ENST00000320548.4
ENST00000581578.1
ENST00000583885.1
ENST00000583641.1
ENST00000581418.1
ENST00000355130.2
ENST00000306823.6
ENST00000392358.2
GPS1
G protein pathway suppressor 1
chr16_+_28722809 3.53 ENST00000566866.1
EIF3C
eukaryotic translation initiation factor 3, subunit C
chr16_+_28722684 3.44 ENST00000331666.6
ENST00000395587.1
ENST00000569690.1
ENST00000564243.1
EIF3C
eukaryotic translation initiation factor 3, subunit C
chrX_+_101854426 3.40 ENST00000536530.1
ENST00000473968.1
ENST00000604957.1
ENST00000477663.1
ENST00000479502.1
ARMCX5
armadillo repeat containing, X-linked 5
chr6_-_109777128 3.39 ENST00000358807.3
ENST00000358577.3
MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr5_+_154238149 3.37 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CNOT8
CCR4-NOT transcription complex, subunit 8
chr1_+_182808474 3.26 ENST00000367549.3
DHX9
DEAH (Asp-Glu-Ala-His) box helicase 9
chr4_-_2243839 3.23 ENST00000511885.2
ENST00000506763.1
ENST00000514395.1
ENST00000502440.1
ENST00000243706.4
ENST00000443786.2
POLN
HAUS3
polymerase (DNA directed) nu
HAUS augmin-like complex, subunit 3
chr14_+_77924204 3.21 ENST00000555133.1
AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr22_-_29196546 3.20 ENST00000403532.3
ENST00000216037.6
XBP1
X-box binding protein 1
chrX_+_9431324 3.18 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr22_+_42017459 3.11 ENST00000405878.1
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr16_-_28415162 3.06 ENST00000398944.3
ENST00000398943.3
ENST00000380876.4
EIF3CL
eukaryotic translation initiation factor 3, subunit C-like
chr20_-_33735070 3.05 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr8_-_99129384 2.98 ENST00000521560.1
ENST00000254878.3
HRSP12
heat-responsive protein 12
chr17_-_80231557 2.87 ENST00000392334.2
ENST00000314028.6
CSNK1D
casein kinase 1, delta
chr6_-_43655511 2.76 ENST00000372133.3
ENST00000372116.1
ENST00000427312.1
MRPS18A
mitochondrial ribosomal protein S18A
chr1_+_24117627 2.74 ENST00000400061.1
LYPLA2
lysophospholipase II
chr9_-_123676827 2.50 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chr19_-_51466681 2.48 ENST00000456750.2
KLK6
kallikrein-related peptidase 6
chr1_-_110933663 2.33 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr1_+_8021713 2.17 ENST00000338639.5
ENST00000493678.1
ENST00000377493.5
PARK7
parkinson protein 7
chr1_-_110933611 2.16 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr10_-_12084770 1.95 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr5_-_146833222 1.90 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr2_+_89890533 1.81 ENST00000429992.2
IGKV2D-40
immunoglobulin kappa variable 2D-40
chr1_+_8021954 1.79 ENST00000377491.1
ENST00000377488.1
PARK7
parkinson protein 7
chr16_+_81069433 1.60 ENST00000299575.4
ATMIN
ATM interactor
chr5_-_180229833 1.60 ENST00000307826.4
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr6_-_49604545 1.37 ENST00000371175.4
ENST00000229810.7
RHAG
Rh-associated glycoprotein
chr9_-_97401782 1.24 ENST00000375326.4
FBP1
fructose-1,6-bisphosphatase 1
chr22_-_42017021 0.74 ENST00000263256.6
DESI1
desumoylating isopeptidase 1
chr22_-_37915247 0.67 ENST00000251973.5
CARD10
caspase recruitment domain family, member 10
chr7_+_148936732 0.49 ENST00000335870.2
ZNF212
zinc finger protein 212
chr19_+_17862274 0.33 ENST00000596536.1
ENST00000593870.1
ENST00000598086.1
ENST00000598932.1
ENST00000595023.1
ENST00000594068.1
ENST00000596507.1
ENST00000595033.1
ENST00000597718.1
FCHO1
FCH domain only 1
chr15_-_25684110 0.19 ENST00000232165.3
UBE3A
ubiquitin protein ligase E3A
chr5_-_77590480 0.14 ENST00000519295.1
ENST00000255194.6
AP3B1
adaptor-related protein complex 3, beta 1 subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB49

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 23.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
2.3 6.8 GO:0035470 positive regulation of vascular wound healing(GO:0035470) regulation of lactation(GO:1903487)
2.1 12.6 GO:0022614 membrane to membrane docking(GO:0022614)
2.1 8.2 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
1.3 10.6 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
1.1 19.4 GO:0060712 spongiotrophoblast layer development(GO:0060712)
1.1 3.4 GO:0019417 sulfur oxidation(GO:0019417)
1.1 7.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
1.0 3.1 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
1.0 3.9 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.8 6.3 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.8 7.0 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.7 16.6 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.7 13.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.7 5.4 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.7 3.3 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.6 6.6 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.5 2.7 GO:0002084 protein depalmitoylation(GO:0002084)
0.5 3.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.5 3.9 GO:0015816 glycine transport(GO:0015816)
0.5 1.4 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.4 15.1 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.4 1.6 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.4 5.7 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.4 5.6 GO:0045116 protein neddylation(GO:0045116)
0.3 4.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.3 1.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.2 3.6 GO:0000338 protein deneddylation(GO:0000338)
0.2 5.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.2 12.0 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.2 8.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.2 1.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 13.2 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.1 2.9 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 2.5 GO:0016540 protein autoprocessing(GO:0016540)
0.1 1.9 GO:0051764 actin crosslink formation(GO:0051764)
0.1 8.7 GO:0032418 lysosome localization(GO:0032418)
0.1 1.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 3.2 GO:0019985 translesion synthesis(GO:0019985)
0.0 3.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 2.5 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 4.0 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 4.5 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.9 GO:0031100 organ regeneration(GO:0031100)
0.0 3.2 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.8 GO:0030449 regulation of complement activation(GO:0030449)
0.0 3.1 GO:0006413 translational initiation(GO:0006413)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 23.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
4.2 16.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.8 5.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.7 5.2 GO:0044393 microspike(GO:0044393)
1.5 15.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.7 3.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.6 12.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.6 3.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.5 8.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.4 13.2 GO:0005839 proteasome core complex(GO:0005839)
0.4 10.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.4 3.2 GO:0070652 HAUS complex(GO:0070652)
0.4 7.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 19.2 GO:0005876 spindle microtubule(GO:0005876)
0.2 9.3 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.7 GO:0032449 CBM complex(GO:0032449)
0.1 2.8 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 3.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 3.6 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 4.0 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 3.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.4 GO:0043195 terminal bouton(GO:0043195)
0.0 1.9 GO:0031941 filamentous actin(GO:0031941)
0.0 12.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 6.7 GO:0005681 spliceosomal complex(GO:0005681)
0.0 6.3 GO:0005819 spindle(GO:0005819)
0.0 0.2 GO:0000502 proteasome complex(GO:0000502)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 4.3 GO:0005759 mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 16.6 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
2.1 8.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
1.4 4.3 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
1.3 21.6 GO:0004526 ribonuclease P activity(GO:0004526)
1.0 4.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.9 5.7 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.9 5.6 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.8 15.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.7 5.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.7 3.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.6 3.9 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.6 13.2 GO:0070628 proteasome binding(GO:0070628)
0.6 6.6 GO:0046790 virion binding(GO:0046790)
0.6 4.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.5 1.4 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.4 13.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4 1.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.3 2.7 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 5.6 GO:0051787 misfolded protein binding(GO:0051787)
0.3 3.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.3 1.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.3 3.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 5.2 GO:0044548 S100 protein binding(GO:0044548)
0.2 1.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 10.0 GO:0031369 translation initiation factor binding(GO:0031369)
0.2 3.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.2 3.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 7.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 2.5 GO:0031996 thioesterase binding(GO:0031996)
0.1 2.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 3.4 GO:0071949 FAD binding(GO:0071949)
0.1 8.0 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 5.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 6.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 3.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 7.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 4.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 6.8 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 3.2 GO:0008013 beta-catenin binding(GO:0008013)
0.0 6.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 4.0 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 4.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 12.6 PID RHOA PATHWAY RhoA signaling pathway
0.2 7.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 16.6 PID E2F PATHWAY E2F transcription factor network
0.1 6.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 6.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 6.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 2.5 PID CD40 PATHWAY CD40/CD40L signaling
0.1 4.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 13.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.5 13.1 REACTOME KINESINS Genes involved in Kinesins
0.5 16.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.5 20.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.4 15.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.3 8.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 3.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 5.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 13.2 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2 3.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.2 12.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 4.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 3.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 5.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.9 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 1.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 5.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 3.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis