Project

GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for ZBTB7A_ZBTB7C

Z-value: 0.38

Motif logo

logo of logo of

Transcription factors associated with ZBTB7A_ZBTB7C

Gene Symbol Gene ID Gene Info
ZBTB7A
ENSG00000178951.4 zinc finger and BTB domain containing 7A
ZBTB7C
ENSG00000184828.5 zinc finger and BTB domain containing 7C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB7Ahg19_v2_chr19_-_4066890_40669430.384.1e-09Click!
ZBTB7Chg19_v2_chr18_-_45663666_45663732,
hg19_v2_chr18_-_45935663_45935793		0.036.8e-01Click!

Activity profile of ZBTB7A_ZBTB7C motif

Sorted Z-values of ZBTB7A_ZBTB7C motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_132112907 38.52 ENST00000458488.2
SEPT8
septin 8
chr5_-_132112921 38.06 ENST00000378721.4
ENST00000378701.1
SEPT8
septin 8
chr1_+_169075554 21.05 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr19_+_35634146 19.57 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD7
FXYD domain containing ion transport regulator 7
chr14_+_29236269 18.22 ENST00000313071.4
FOXG1
forkhead box G1
chr15_-_64126084 17.96 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr7_-_94285402 17.86 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr4_+_41258786 17.86 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr11_-_66115032 17.46 ENST00000311181.4
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr17_+_40834580 16.77 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr20_+_36149602 16.56 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr5_+_139493665 16.24 ENST00000331327.3
PURA
purine-rich element binding protein A
chr5_-_132113036 15.75 ENST00000378706.1
SEPT8
septin 8
chr20_+_44034804 15.51 ENST00000357275.2
ENST00000372720.3
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr7_-_94285472 14.71 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr14_+_100150622 14.58 ENST00000261835.3
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr16_+_15528332 14.29 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr20_+_44034676 14.02 ENST00000372723.3
ENST00000372722.3
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_-_117747607 13.77 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chr12_+_13197218 13.66 ENST00000197268.8
KIAA1467
KIAA1467
chr7_-_94285511 13.62 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr11_-_117747434 13.34 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr16_-_19896220 13.02 ENST00000562469.1
ENST00000300571.2
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr6_-_46459675 12.98 ENST00000306764.7
RCAN2
regulator of calcineurin 2
chr5_+_76506706 11.62 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B
phosphodiesterase 8B
chr6_-_122792919 11.18 ENST00000339697.4
SERINC1
serine incorporator 1
chr17_+_43972010 9.53 ENST00000334239.8
ENST00000446361.3
MAPT
microtubule-associated protein tau
chr3_-_33759541 9.40 ENST00000468888.2
CLASP2
cytoplasmic linker associated protein 2
chr5_-_132113083 9.26 ENST00000296873.7
SEPT8
septin 8
chrX_-_51812268 9.23 ENST00000486010.1
ENST00000497164.1
ENST00000360134.6
ENST00000485287.1
ENST00000335504.5
ENST00000431659.1
MAGED4B
melanoma antigen family D, 4B
chr9_-_123476612 8.83 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr11_-_1330834 8.80 ENST00000525159.1
ENST00000317204.6
ENST00000542915.1
ENST00000527938.1
ENST00000530541.1
ENST00000263646.7
TOLLIP
toll interacting protein
chr3_-_33759699 8.43 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
CLASP2
cytoplasmic linker associated protein 2
chr5_-_132113559 8.39 ENST00000448933.1
SEPT8
septin 8
chr14_-_22005062 8.37 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr17_-_1532106 8.01 ENST00000301335.5
ENST00000382147.4
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr7_-_51384451 7.76 ENST00000441453.1
ENST00000265136.7
ENST00000395542.2
ENST00000395540.2
COBL
cordon-bleu WH2 repeat protein
chr1_-_95007193 6.77 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr9_+_74526384 6.74 ENST00000334731.2
ENST00000377031.3
C9orf85
chromosome 9 open reading frame 85
chr22_+_31031639 6.62 ENST00000343605.4
ENST00000300385.8
SLC35E4
solute carrier family 35, member E4
chr11_+_133938820 6.38 ENST00000299106.4
ENST00000529443.2
JAM3
junctional adhesion molecule 3
chr5_-_443239 6.37 ENST00000408966.2
C5orf55
chromosome 5 open reading frame 55
chrX_+_133507327 6.32 ENST00000332070.3
ENST00000394292.1
ENST00000370799.1
ENST00000416404.2
PHF6
PHD finger protein 6
chr5_+_178286925 6.04 ENST00000322434.3
ZNF354B
zinc finger protein 354B
chr11_+_133938955 6.02 ENST00000534549.1
ENST00000441717.3
JAM3
junctional adhesion molecule 3
chr5_-_138210977 5.85 ENST00000274711.6
ENST00000521094.2
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr8_-_144242020 5.47 ENST00000414417.2
LY6H
lymphocyte antigen 6 complex, locus H
chr6_-_36953833 5.46 ENST00000538808.1
ENST00000460219.1
ENST00000373616.5
ENST00000373627.5
MTCH1
mitochondrial carrier 1
chr13_+_96204961 5.41 ENST00000299339.2
CLDN10
claudin 10
chr15_-_83876758 5.34 ENST00000299633.4
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr14_+_29234870 5.33 ENST00000382535.3
FOXG1
forkhead box G1
chr15_-_23932437 5.08 ENST00000331837.4
NDN
necdin, melanoma antigen (MAGE) family member
chr8_-_144241664 4.91 ENST00000342752.4
LY6H
lymphocyte antigen 6 complex, locus H
chr8_-_144241432 4.90 ENST00000430474.2
LY6H
lymphocyte antigen 6 complex, locus H
chr1_-_151431909 4.73 ENST00000361398.3
ENST00000271715.2
POGZ
pogo transposable element with ZNF domain
chr17_-_8534031 4.72 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
MYH10
myosin, heavy chain 10, non-muscle
chr17_-_5372271 4.72 ENST00000225296.3
DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr17_-_8534067 4.59 ENST00000360416.3
ENST00000269243.4
MYH10
myosin, heavy chain 10, non-muscle
chr20_-_36156293 4.45 ENST00000373537.2
ENST00000414542.2
BLCAP
bladder cancer associated protein
chr4_+_156588350 4.42 ENST00000296518.7
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr8_+_9413410 4.36 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr12_-_42631529 4.36 ENST00000548917.1
YAF2
YY1 associated factor 2
chr20_-_36156125 4.33 ENST00000397135.1
ENST00000397137.1
BLCAP
bladder cancer associated protein
chr2_+_136289030 4.27 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3HDM1
R3H domain containing 1
chr14_-_22005018 4.27 ENST00000546363.1
SALL2
spalt-like transcription factor 2
chr2_-_152118352 4.26 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr3_+_15468862 4.19 ENST00000396842.2
EAF1
ELL associated factor 1
chr2_+_25016282 4.13 ENST00000260662.1
CENPO
centromere protein O
chr2_+_198669365 4.11 ENST00000428675.1
PLCL1
phospholipase C-like 1
chr3_+_108308513 4.10 ENST00000361582.3
DZIP3
DAZ interacting zinc finger protein 3
chr5_+_149109825 4.01 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr2_+_25015968 3.79 ENST00000380834.2
ENST00000473706.1
CENPO
centromere protein O
chr5_-_114515734 3.77 ENST00000514154.1
ENST00000282369.3
TRIM36
tripartite motif containing 36
chr17_-_4890919 3.73 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
CAMTA2
calmodulin binding transcription activator 2
chr3_-_149470229 3.56 ENST00000473414.1
COMMD2
COMM domain containing 2
chr3_-_15469006 3.55 ENST00000443029.1
ENST00000383790.3
ENST00000383789.5
METTL6
methyltransferase like 6
chr8_-_38853990 3.45 ENST00000456845.2
ENST00000397070.2
ENST00000517872.1
ENST00000412303.1
ENST00000456397.2
TM2D2
TM2 domain containing 2
chr8_-_101964231 3.40 ENST00000521309.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr8_-_101964265 3.23 ENST00000395958.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr12_+_57943781 3.13 ENST00000455537.2
ENST00000286452.5
KIF5A
kinesin family member 5A
chr8_+_26240414 3.01 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr1_-_43205811 2.99 ENST00000372539.3
ENST00000296387.1
ENST00000539749.1
CLDN19
claudin 19
chr17_-_7137582 2.89 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chr6_+_87865262 2.87 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chrX_-_119603138 2.86 ENST00000200639.4
ENST00000371335.4
ENST00000538785.1
ENST00000434600.2
LAMP2
lysosomal-associated membrane protein 2
chr19_+_5904866 2.80 ENST00000339485.3
VMAC
vimentin-type intermediate filament associated coiled-coil protein
chr14_-_102771462 2.70 ENST00000522874.1
MOK
MOK protein kinase
chr9_+_132934835 2.68 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chrX_-_153141302 2.68 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1CAM
L1 cell adhesion molecule
chr4_+_39184024 2.67 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WDR19
WD repeat domain 19
chr9_-_139094988 2.65 ENST00000371746.3
LHX3
LIM homeobox 3
chr5_-_140070897 2.63 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
HARS
histidyl-tRNA synthetase
chr7_+_66093851 2.56 ENST00000275532.3
KCTD7
potassium channel tetramerization domain containing 7
chr5_+_175792459 2.50 ENST00000310389.5
ARL10
ADP-ribosylation factor-like 10
chr14_-_54955721 2.45 ENST00000554908.1
GMFB
glia maturation factor, beta
chr19_+_49622646 2.35 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr9_-_131790464 2.21 ENST00000417224.1
ENST00000416629.1
ENST00000372559.1
SH3GLB2
SH3-domain GRB2-like endophilin B2
chr19_-_5567996 2.20 ENST00000448587.1
TINCR
tissue differentiation-inducing non-protein coding RNA
chr1_+_167905894 2.19 ENST00000367843.3
ENST00000432587.2
ENST00000312263.6
DCAF6
DDB1 and CUL4 associated factor 6
chr17_-_37844267 2.18 ENST00000579146.1
ENST00000378011.4
ENST00000429199.2
ENST00000300658.4
PGAP3
post-GPI attachment to proteins 3
chr3_-_100120223 2.17 ENST00000284320.5
TOMM70A
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
chr14_+_70233810 2.14 ENST00000394366.2
ENST00000553548.1
ENST00000553369.1
ENST00000557154.1
ENST00000451983.2
ENST00000553635.1
SRSF5
serine/arginine-rich splicing factor 5
chr3_+_23986748 2.14 ENST00000312521.4
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr9_+_131873227 2.13 ENST00000358994.4
ENST00000455292.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr3_-_164914640 2.08 ENST00000241274.3
SLITRK3
SLIT and NTRK-like family, member 3
chr4_-_76598326 2.02 ENST00000503660.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr4_-_16085314 2.01 ENST00000510224.1
PROM1
prominin 1
chr14_+_24583836 1.99 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DCAF11
DDB1 and CUL4 associated factor 11
chr4_-_16085340 1.94 ENST00000508167.1
PROM1
prominin 1
chr17_-_4890649 1.93 ENST00000361571.5
CAMTA2
calmodulin binding transcription activator 2
chr10_+_70091812 1.92 ENST00000265866.7
HNRNPH3
heterogeneous nuclear ribonucleoprotein H3 (2H9)
chr14_-_102771516 1.78 ENST00000524214.1
ENST00000193029.6
ENST00000361847.2
MOK
MOK protein kinase
chr4_-_146101304 1.78 ENST00000447906.2
OTUD4
OTU domain containing 4
chr19_+_40697514 1.77 ENST00000253055.3
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr11_-_63536113 1.76 ENST00000433688.1
ENST00000546282.2
C11orf95
RP11-466C23.4
chromosome 11 open reading frame 95
RP11-466C23.4
chr1_-_21616901 1.76 ENST00000436918.2
ENST00000374893.6
ECE1
endothelin converting enzyme 1
chr5_-_72861484 1.74 ENST00000296785.3
ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr14_+_59655369 1.71 ENST00000360909.3
ENST00000351081.1
ENST00000556135.1
DAAM1
dishevelled associated activator of morphogenesis 1
chr14_-_24584138 1.69 ENST00000558280.1
ENST00000561028.1
NRL
neural retina leucine zipper
chr19_-_14228541 1.65 ENST00000590853.1
ENST00000308677.4
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr22_+_42229100 1.64 ENST00000361204.4
SREBF2
sterol regulatory element binding transcription factor 2
chr16_+_84002234 1.55 ENST00000305202.4
NECAB2
N-terminal EF-hand calcium binding protein 2
chr17_+_29158962 1.54 ENST00000321990.4
ATAD5
ATPase family, AAA domain containing 5
chr11_-_129872712 1.51 ENST00000358825.5
ENST00000360871.3
ENST00000528746.1
PRDM10
PR domain containing 10
chrX_+_67913471 1.49 ENST00000374597.3
STARD8
StAR-related lipid transfer (START) domain containing 8
chr4_+_72052964 1.47 ENST00000264485.5
ENST00000425175.1
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr16_-_49315731 1.46 ENST00000219197.6
CBLN1
cerebellin 1 precursor
chr1_+_25664408 1.45 ENST00000374358.4
TMEM50A
transmembrane protein 50A
chr12_-_49351148 1.43 ENST00000398092.4
ENST00000539611.1
RP11-302B13.5
ARF3
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chrX_-_17878827 1.39 ENST00000360011.1
RAI2
retinoic acid induced 2
chr19_-_46296011 1.37 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr5_+_443268 1.36 ENST00000512944.1
EXOC3
exocyst complex component 3
chr21_-_45079341 1.32 ENST00000443485.1
ENST00000291560.2
HSF2BP
heat shock transcription factor 2 binding protein
chr8_-_74884511 1.29 ENST00000518127.1
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr10_+_49514698 1.28 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr8_-_101963677 1.24 ENST00000395956.3
ENST00000395953.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr12_-_107487604 1.23 ENST00000008527.5
CRY1
cryptochrome 1 (photolyase-like)
chr20_-_58508702 1.18 ENST00000357552.3
ENST00000425931.1
SYCP2
synaptonemal complex protein 2
chr7_+_43152191 1.17 ENST00000395891.2
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr5_+_78407602 1.14 ENST00000274353.5
ENST00000524080.1
BHMT
betaine--homocysteine S-methyltransferase
chr17_+_37844331 1.11 ENST00000578199.1
ENST00000406381.2
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr19_-_56988677 1.11 ENST00000504904.3
ENST00000292069.6
ZNF667
zinc finger protein 667
chr17_+_79990058 1.08 ENST00000584341.1
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chrX_+_135579238 1.07 ENST00000535601.1
ENST00000448450.1
ENST00000425695.1
HTATSF1
HIV-1 Tat specific factor 1
chr8_-_74884399 1.07 ENST00000520210.1
ENST00000602840.1
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr19_-_59070239 1.04 ENST00000595957.1
ENST00000253023.3
UBE2M
ubiquitin-conjugating enzyme E2M
chr2_+_242255297 1.02 ENST00000401990.1
ENST00000407971.1
ENST00000436795.1
ENST00000411484.1
ENST00000434955.1
ENST00000402092.2
ENST00000441533.1
ENST00000443492.1
ENST00000437066.1
ENST00000429791.1
SEPT2
septin 2
chr20_-_35492048 1.02 ENST00000237536.4
SOGA1
suppressor of glucose, autophagy associated 1
chr6_-_16761678 1.02 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr1_-_151431647 1.02 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr6_+_125474939 0.98 ENST00000527711.1
TPD52L1
tumor protein D52-like 1
chr6_+_125475335 0.94 ENST00000532429.1
ENST00000534199.1
TPD52L1
tumor protein D52-like 1
chr19_-_49622348 0.91 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr15_+_27112948 0.91 ENST00000555060.1
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr1_+_110754094 0.87 ENST00000369787.3
ENST00000413138.3
ENST00000438661.2
KCNC4
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr9_+_35161998 0.86 ENST00000396787.1
ENST00000378495.3
ENST00000378496.4
UNC13B
unc-13 homolog B (C. elegans)
chr12_+_50355647 0.85 ENST00000293599.6
AQP5
aquaporin 5
chr21_-_47648665 0.82 ENST00000450351.1
ENST00000522411.1
ENST00000356396.4
ENST00000397728.3
ENST00000457828.2
LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr22_+_21369316 0.68 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
chr6_-_34113856 0.67 ENST00000538487.2
GRM4
glutamate receptor, metabotropic 4
chr15_+_92397051 0.67 ENST00000424469.2
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chrX_+_44732757 0.63 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A
lysine (K)-specific demethylase 6A
chr3_+_50126341 0.62 ENST00000347869.3
ENST00000469838.1
ENST00000404526.2
ENST00000441305.1
RBM5
RNA binding motif protein 5
chr6_+_126070726 0.61 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr19_+_38755042 0.61 ENST00000301244.7
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr6_+_125474992 0.59 ENST00000528193.1
TPD52L1
tumor protein D52-like 1
chr4_-_119274121 0.58 ENST00000296498.3
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr19_+_39833036 0.49 ENST00000602243.1
ENST00000598913.1
ENST00000314471.6
SAMD4B
sterile alpha motif domain containing 4B
chr4_-_83351005 0.49 ENST00000295470.5
HNRNPDL
heterogeneous nuclear ribonucleoprotein D-like
chr2_-_97405775 0.48 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L
lectin, mannose-binding 2-like
chr1_+_167906056 0.46 ENST00000367840.3
DCAF6
DDB1 and CUL4 associated factor 6
chrX_-_17879356 0.42 ENST00000331511.1
ENST00000415486.3
ENST00000545871.1
ENST00000451717.1
RAI2
retinoic acid induced 2
chr6_-_30043539 0.42 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr20_-_61493115 0.41 ENST00000335351.3
ENST00000217162.5
TCFL5
transcription factor-like 5 (basic helix-loop-helix)
chr9_-_96717654 0.40 ENST00000253968.6
BARX1
BARX homeobox 1
chr4_-_5021164 0.39 ENST00000506508.1
ENST00000509419.1
ENST00000307746.4
CYTL1
cytokine-like 1
chr5_-_139283982 0.30 ENST00000340391.3
NRG2
neuregulin 2
chr8_-_74884482 0.28 ENST00000520242.1
ENST00000519082.1
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr6_+_157802165 0.27 ENST00000414563.2
ENST00000359775.5
ZDHHC14
zinc finger, DHHC-type containing 14
chr20_-_17662705 0.25 ENST00000455029.2
RRBP1
ribosome binding protein 1
chr22_+_38035459 0.23 ENST00000357436.4
SH3BP1
SH3-domain binding protein 1
chr17_+_79989937 0.21 ENST00000580965.1
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr4_+_72053017 0.21 ENST00000351898.6
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr8_-_74884341 0.18 ENST00000284811.8
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr20_+_37590942 0.13 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr19_+_36203830 0.10 ENST00000262630.3
ZBTB32
zinc finger and BTB domain containing 32
chr19_+_38755203 0.08 ENST00000587090.1
ENST00000454580.3
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr5_-_33984786 0.05 ENST00000296589.4
SLC45A2
solute carrier family 45, member 2
chr6_-_33290580 0.05 ENST00000446511.1
ENST00000446403.1
ENST00000414083.2
ENST00000266000.6
ENST00000374542.5
DAXX
death-domain associated protein
chr5_-_33984741 0.04 ENST00000382102.3
ENST00000509381.1
ENST00000342059.3
ENST00000345083.5
SLC45A2
solute carrier family 45, member 2
chr16_+_66400533 0.04 ENST00000341529.3
CDH5
cadherin 5, type 2 (vascular endothelium)

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB7A_ZBTB7C

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 17.9 GO:0007412 axon target recognition(GO:0007412)
5.3 21.1 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
3.1 9.3 GO:0021592 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
2.9 14.3 GO:1903976 negative regulation of glial cell migration(GO:1903976)
2.4 16.8 GO:0002175 protein localization to paranode region of axon(GO:0002175)
2.3 6.8 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
2.2 17.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.9 7.8 GO:0001757 somite specification(GO:0001757)
1.9 9.5 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
1.7 16.6 GO:0009249 protein lipoylation(GO:0009249)
1.6 16.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.5 14.6 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.5 4.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.4 12.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.3 4.0 GO:2000768 positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
1.2 18.0 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
1.0 3.1 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.9 11.2 GO:0015825 L-serine transport(GO:0015825)
0.8 13.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.7 4.4 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.7 2.2 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.7 2.0 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.7 2.7 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.6 7.4 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.6 45.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.6 8.8 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.5 7.5 GO:0090168 Golgi reassembly(GO:0090168)
0.5 3.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.5 2.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.5 5.5 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.4 5.7 GO:0051382 kinetochore assembly(GO:0051382)
0.4 2.6 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.4 1.8 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.4 1.3 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.4 1.7 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.4 1.6 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.4 3.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 4.0 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.3 13.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.3 4.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.3 11.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.3 1.5 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) positive regulation of long term synaptic depression(GO:1900454)
0.3 0.9 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.3 8.0 GO:0015804 neutral amino acid transport(GO:0015804)
0.3 7.9 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 2.9 GO:1905146 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) lysosomal protein catabolic process(GO:1905146)
0.2 2.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 15.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 5.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 0.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 0.6 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.2 1.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.2 5.1 GO:0007413 axonal fasciculation(GO:0007413)
0.2 8.8 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.2 5.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 1.1 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.2 1.3 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.2 1.6 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.2 0.7 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 0.8 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 1.9 GO:0034063 stress granule assembly(GO:0034063)
0.1 1.4 GO:0051601 exocyst localization(GO:0051601)
0.1 1.5 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 33.3 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 0.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 3.8 GO:0007340 acrosome reaction(GO:0007340)
0.1 2.1 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.1 1.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 2.1 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 1.2 GO:0035112 genitalia morphogenesis(GO:0035112)
0.1 12.2 GO:0021915 neural tube development(GO:0021915)
0.1 22.5 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.1 1.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 1.0 GO:0045116 protein neddylation(GO:0045116)
0.1 1.7 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 2.2 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.1 21.2 GO:0007568 aging(GO:0007568)
0.1 4.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.9 GO:0060384 innervation(GO:0060384)
0.0 2.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 2.7 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.7 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 1.1 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 1.6 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.7 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0 0.9 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 1.2 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.4 GO:0048536 spleen development(GO:0048536)
0.0 1.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.8 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 1.0 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 46.2 GO:0016012 sarcoglycan complex(GO:0016012)
2.4 29.2 GO:0033010 paranodal junction(GO:0033010)
1.9 9.5 GO:0045298 tubulin complex(GO:0045298)
1.9 9.3 GO:0097513 myosin II filament(GO:0097513)
1.8 17.8 GO:0045180 basal cortex(GO:0045180)
1.8 8.8 GO:0045323 interleukin-1 receptor complex(GO:0045323)
1.1 16.2 GO:0005662 DNA replication factor A complex(GO:0005662)
1.1 21.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.0 7.8 GO:0044294 dendritic growth cone(GO:0044294)
0.8 4.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.7 2.9 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.4 2.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.4 1.8 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.4 12.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.4 1.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 17.9 GO:1904115 axon cytoplasm(GO:1904115)
0.3 1.7 GO:1990393 3M complex(GO:1990393)
0.3 29.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 6.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.3 0.9 GO:0044305 calyx of Held(GO:0044305)
0.3 4.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.3 2.7 GO:0031045 dense core granule(GO:0031045)
0.2 4.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 3.1 GO:0035253 ciliary rootlet(GO:0035253)
0.2 1.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 2.7 GO:0044295 axonal growth cone(GO:0044295)
0.2 4.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 6.1 GO:0097546 ciliary base(GO:0097546)
0.1 2.4 GO:0000145 exocyst(GO:0000145)
0.1 4.0 GO:0016592 mediator complex(GO:0016592)
0.1 3.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.2 GO:0000800 lateral element(GO:0000800)
0.1 12.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 4.2 GO:0045171 intercellular bridge(GO:0045171)
0.1 6.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 8.4 GO:0005923 bicellular tight junction(GO:0005923)
0.1 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0043073 male germ cell nucleus(GO:0001673) germ cell nucleus(GO:0043073)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 4.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 2.0 GO:0016235 aggresome(GO:0016235) lateral plasma membrane(GO:0016328)
0.0 7.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 75.7 GO:0005856 cytoskeleton(GO:0005856)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.4 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 66.9 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 16.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
4.5 17.9 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
2.9 8.8 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
2.4 9.5 GO:0099609 microtubule lateral binding(GO:0099609)
2.2 13.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.3 21.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.9 11.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.9 45.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.7 17.8 GO:0002162 dystroglycan binding(GO:0002162)
0.7 2.2 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.7 18.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.6 4.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.5 4.7 GO:0000182 rDNA binding(GO:0000182)
0.4 1.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.4 5.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 13.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.4 1.5 GO:0031685 adenosine receptor binding(GO:0031685)
0.4 1.1 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.3 4.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.3 8.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.3 4.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.3 2.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 11.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 0.8 GO:0016866 intramolecular transferase activity(GO:0016866)
0.2 105.9 GO:0005525 GTP binding(GO:0005525)
0.2 0.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 1.0 GO:0034046 poly(G) binding(GO:0034046)
0.2 2.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 5.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 0.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 1.0 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.2 7.8 GO:0003785 actin monomer binding(GO:0003785)
0.2 0.6 GO:0035939 microsatellite binding(GO:0035939)
0.1 7.5 GO:0043531 ADP binding(GO:0043531)
0.1 15.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 13.1 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 1.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.1 GO:0001042 RNA polymerase I core binding(GO:0001042) ErbB-3 class receptor binding(GO:0043125)
0.1 1.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 2.1 GO:0043422 protein kinase B binding(GO:0043422)
0.1 3.0 GO:0005521 lamin binding(GO:0005521)
0.1 1.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 14.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 3.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 4.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 2.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.7 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 2.9 GO:0042805 actinin binding(GO:0042805)
0.1 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.8 GO:0015250 water channel activity(GO:0015250)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 3.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 2.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 6.8 GO:0002020 protease binding(GO:0002020)
0.0 1.8 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 5.1 GO:0008168 methyltransferase activity(GO:0008168)
0.0 5.3 GO:0008017 microtubule binding(GO:0008017)
0.0 4.4 GO:0042393 histone binding(GO:0042393)
0.0 7.5 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0008066 glutamate receptor activity(GO:0008066)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 14.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 17.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 12.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 10.1 PID IL1 PATHWAY IL1-mediated signaling events
0.2 7.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 3.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 15.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 2.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 5.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 1.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 2.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.4 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.0 PID CDC42 PATHWAY CDC42 signaling events
0.0 3.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 14.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.6 23.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.5 16.1 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.3 7.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.3 7.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 9.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 10.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 8.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 6.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 7.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 3.1 REACTOME KINESINS Genes involved in Kinesins
0.1 1.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 8.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 4.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 4.4 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 10.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 2.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.9 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 8.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 4.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 4.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 4.1 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 3.3 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway