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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for ZIC1

Z-value: 0.99

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Transcription factors associated with ZIC1

Gene Symbol Gene ID Gene Info
ZIC1
ENSG00000152977.5 Zic family member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC1hg19_v2_chr3_+_147127142_1471271710.119.3e-02Click!

Activity profile of ZIC1 motif

Sorted Z-values of ZIC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_3028354 25.85 ENST00000586422.1
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr12_-_15038779 18.63 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr6_+_31949801 16.47 ENST00000428956.2
ENST00000498271.1
C4A
complement component 4A (Rodgers blood group)
chr19_+_45409011 16.03 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE
apolipoprotein E
chr11_-_2160180 15.94 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr19_+_41509851 14.31 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr3_-_58563094 14.27 ENST00000464064.1
FAM107A
family with sequence similarity 107, member A
chr8_-_120685608 14.11 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr2_-_99552620 13.47 ENST00000428096.1
ENST00000397899.2
ENST00000420294.1
KIAA1211L
KIAA1211-like
chr19_-_58609570 12.55 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
ZSCAN18
zinc finger and SCAN domain containing 18
chr1_+_46668994 10.99 ENST00000371980.3
LURAP1
leucine rich adaptor protein 1
chr4_+_24797085 10.79 ENST00000382120.3
SOD3
superoxide dismutase 3, extracellular
chr5_-_64920115 10.44 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr1_+_22962948 10.08 ENST00000374642.3
C1QA
complement component 1, q subcomponent, A chain
chr1_+_22963158 9.47 ENST00000438241.1
C1QA
complement component 1, q subcomponent, A chain
chr4_-_7105056 8.44 ENST00000504402.1
ENST00000499242.2
ENST00000501888.2
RP11-367J11.3
RP11-367J11.3
chr11_-_2182388 8.34 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
INS
INS-IGF2
insulin
INS-IGF2 readthrough
chr19_+_54024251 8.13 ENST00000253144.9
ZNF331
zinc finger protein 331
chr5_+_64920543 7.64 ENST00000399438.3
ENST00000510585.2
TRAPPC13
CTC-534A2.2
trafficking protein particle complex 13
CDNA FLJ26957 fis, clone SLV00486; Uncharacterized protein
chr2_-_208989225 7.55 ENST00000264376.4
CRYGD
crystallin, gamma D
chr19_-_42931567 7.54 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr13_-_29069232 7.41 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
FLT1
fms-related tyrosine kinase 1
chr19_-_16582815 7.32 ENST00000455140.2
ENST00000248070.6
ENST00000594975.1
EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
chr3_+_71803201 7.29 ENST00000304411.2
GPR27
G protein-coupled receptor 27
chr11_-_73309228 7.12 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr17_+_40913210 6.67 ENST00000253796.5
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr2_-_89399845 6.65 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr1_+_18958008 6.51 ENST00000420770.2
ENST00000400661.3
PAX7
paired box 7
chr18_+_76829441 6.48 ENST00000458297.2
ATP9B
ATPase, class II, type 9B
chr9_+_132934835 6.45 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr9_-_127263265 6.31 ENST00000373587.3
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr2_+_90248739 6.30 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr17_-_43045439 6.03 ENST00000253407.3
C1QL1
complement component 1, q subcomponent-like 1
chr19_-_16582754 5.97 ENST00000602151.1
ENST00000597937.1
ENST00000535753.2
EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
chr14_-_50999190 5.89 ENST00000557390.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr7_-_135412925 5.83 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chrX_+_77166172 5.78 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr1_-_177134024 5.70 ENST00000367654.3
ASTN1
astrotactin 1
chr2_+_79347577 5.68 ENST00000233735.1
REG1A
regenerating islet-derived 1 alpha
chr6_+_28109703 5.66 ENST00000457389.2
ENST00000330236.6
ZKSCAN8
zinc finger with KRAB and SCAN domains 8
chrX_+_68835911 5.58 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA
ectodysplasin A
chrX_+_134975858 5.56 ENST00000537770.1
SAGE1
sarcoma antigen 1
chrX_+_134975753 5.56 ENST00000535938.1
SAGE1
sarcoma antigen 1
chr22_-_24622080 5.44 ENST00000425408.1
GGT5
gamma-glutamyltransferase 5
chrX_-_78622805 5.39 ENST00000373298.2
ITM2A
integral membrane protein 2A
chr1_-_71513471 5.26 ENST00000370931.3
ENST00000356595.4
ENST00000306666.5
ENST00000370932.2
ENST00000351052.5
ENST00000414819.1
ENST00000370924.4
PTGER3
prostaglandin E receptor 3 (subtype EP3)
chr3_-_53080047 5.26 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1
Scm-like with four mbt domains 1
chr18_-_52989217 5.24 ENST00000570287.2
TCF4
transcription factor 4
chr16_-_31100284 5.15 ENST00000280606.6
PRSS53
protease, serine, 53
chr15_+_73976715 5.10 ENST00000558689.1
ENST00000560786.2
ENST00000561213.1
ENST00000563584.1
ENST00000561416.1
CD276
CD276 molecule
chr9_-_16870704 5.10 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chrX_+_18725758 5.05 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr1_-_20446020 4.80 ENST00000375105.3
PLA2G2D
phospholipase A2, group IID
chr22_+_41956767 4.70 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr2_+_11679963 4.57 ENST00000263834.5
GREB1
growth regulation by estrogen in breast cancer 1
chr22_+_44319619 4.45 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr1_+_62417957 4.40 ENST00000307297.7
ENST00000543708.1
INADL
InaD-like (Drosophila)
chr22_+_44319648 4.33 ENST00000423180.2
PNPLA3
patatin-like phospholipase domain containing 3
chr6_-_87804815 4.31 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr19_-_46142637 4.27 ENST00000590043.1
ENST00000589876.1
EML2
echinoderm microtubule associated protein like 2
chr17_-_4464081 4.26 ENST00000574154.1
GGT6
gamma-glutamyltransferase 6
chr15_-_71407806 4.23 ENST00000566432.1
ENST00000567117.1
CT62
cancer/testis antigen 62
chr8_+_85097110 4.15 ENST00000517638.1
ENST00000522647.1
RALYL
RALY RNA binding protein-like
chr4_+_95917383 4.09 ENST00000512312.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr10_-_62493223 4.09 ENST00000373827.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_-_60392452 4.08 ENST00000371204.3
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
chr12_-_11002063 4.05 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chrY_+_4868267 3.99 ENST00000333703.4
PCDH11Y
protocadherin 11 Y-linked
chr9_+_35792151 3.74 ENST00000342694.2
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr12_-_11036844 3.71 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr19_+_42772659 3.70 ENST00000572681.2
CIC
capicua transcriptional repressor
chr10_+_118350468 3.69 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr18_+_76829385 3.68 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATP9B
ATPase, class II, type 9B
chr4_-_186733363 3.68 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr17_+_60704762 3.64 ENST00000303375.5
MRC2
mannose receptor, C type 2
chr7_+_29874341 3.64 ENST00000409290.1
ENST00000242140.5
WIPF3
WAS/WASL interacting protein family, member 3
chr6_-_35656712 3.63 ENST00000357266.4
ENST00000542713.1
FKBP5
FK506 binding protein 5
chrX_+_91034260 3.59 ENST00000395337.2
PCDH11X
protocadherin 11 X-linked
chr13_+_102104952 3.58 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr17_-_39197699 3.47 ENST00000306271.4
KRTAP1-1
keratin associated protein 1-1
chr19_-_46142680 3.42 ENST00000245925.3
EML2
echinoderm microtubule associated protein like 2
chr1_-_211307315 3.40 ENST00000271751.4
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr4_-_109089573 3.38 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr10_+_118350522 3.31 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1
pancreatic lipase-related protein 1
chr2_+_169926047 3.31 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr15_+_41245160 3.29 ENST00000444189.2
ENST00000446533.3
CHAC1
ChaC, cation transport regulator homolog 1 (E. coli)
chr15_-_71407833 3.26 ENST00000449977.2
CT62
cancer/testis antigen 62
chr4_-_175750364 3.22 ENST00000340217.5
ENST00000274093.3
GLRA3
glycine receptor, alpha 3
chr3_+_50192499 3.15 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr12_+_13197218 3.13 ENST00000197268.8
KIAA1467
KIAA1467
chr4_-_7941596 3.03 ENST00000420658.1
ENST00000358461.2
AFAP1
actin filament associated protein 1
chr11_+_65779283 2.88 ENST00000312134.2
CST6
cystatin E/M
chr10_+_50818343 2.87 ENST00000374115.3
SLC18A3
solute carrier family 18 (vesicular acetylcholine transporter), member 3
chr11_+_120207787 2.84 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr11_+_63606477 2.79 ENST00000508192.1
ENST00000361128.5
MARK2
MAP/microtubule affinity-regulating kinase 2
chr1_+_17559776 2.76 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1
peptidyl arginine deiminase, type I
chr17_-_56609302 2.75 ENST00000581607.1
ENST00000317256.6
ENST00000426861.1
ENST00000580809.1
ENST00000577729.1
ENST00000583291.1
SEPT4
septin 4
chr22_-_23922448 2.65 ENST00000438703.1
ENST00000330377.2
IGLL1
immunoglobulin lambda-like polypeptide 1
chr7_-_100493744 2.60 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr22_+_21369316 2.54 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
chr3_-_45838011 2.50 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr18_-_52989525 2.49 ENST00000457482.3
TCF4
transcription factor 4
chr17_-_5372271 2.46 ENST00000225296.3
DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr2_-_98280383 2.45 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr7_+_39017504 2.38 ENST00000403058.1
POU6F2
POU class 6 homeobox 2
chr7_+_107384579 2.19 ENST00000222597.2
ENST00000415884.2
CBLL1
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr11_+_63606373 2.19 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2
MAP/microtubule affinity-regulating kinase 2
chr11_+_15095108 2.09 ENST00000324229.6
ENST00000533448.1
CALCB
calcitonin-related polypeptide beta
chr10_-_81708854 2.05 ENST00000372292.3
SFTPD
surfactant protein D
chr11_+_63606558 2.04 ENST00000350490.7
ENST00000502399.3
MARK2
MAP/microtubule affinity-regulating kinase 2
chr11_+_66824276 1.89 ENST00000308831.2
RHOD
ras homolog family member D
chr3_-_45837959 1.87 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr1_+_1567474 1.86 ENST00000356026.5
MMP23B
matrix metallopeptidase 23B
chr4_-_121993673 1.85 ENST00000379692.4
NDNF
neuron-derived neurotrophic factor
chr19_+_34287751 1.84 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr2_+_89184868 1.79 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr6_-_35656685 1.61 ENST00000539068.1
ENST00000540787.1
FKBP5
FK506 binding protein 5
chr21_+_45209394 1.58 ENST00000497547.1
RRP1
ribosomal RNA processing 1
chr22_+_29702572 1.52 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
GAS2L1
growth arrest-specific 2 like 1
chr15_+_81589254 1.48 ENST00000394652.2
IL16
interleukin 16
chr19_+_10196781 1.45 ENST00000253110.11
C19orf66
chromosome 19 open reading frame 66
chr1_+_89990431 1.39 ENST00000330947.2
ENST00000358200.4
LRRC8B
leucine rich repeat containing 8 family, member B
chr1_-_111991908 1.38 ENST00000235090.5
WDR77
WD repeat domain 77
chr15_+_63340553 1.35 ENST00000334895.5
TPM1
tropomyosin 1 (alpha)
chr7_+_150264365 1.21 ENST00000255945.2
ENST00000461940.1
GIMAP4
GTPase, IMAP family member 4
chr22_-_23922410 1.20 ENST00000249053.3
IGLL1
immunoglobulin lambda-like polypeptide 1
chr10_-_101945771 1.17 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr11_-_22647350 1.17 ENST00000327470.3
FANCF
Fanconi anemia, complementation group F
chr16_-_67427389 1.09 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3
tubulin polymerization-promoting protein family member 3
chr3_-_50329835 1.05 ENST00000429673.2
IFRD2
interferon-related developmental regulator 2
chr17_-_39507064 1.04 ENST00000007735.3
KRT33A
keratin 33A
chrX_+_24711997 1.02 ENST00000379068.3
ENST00000379059.3
POLA1
polymerase (DNA directed), alpha 1, catalytic subunit
chr6_-_168476511 1.02 ENST00000440994.2
FRMD1
FERM domain containing 1
chr1_+_16348366 1.00 ENST00000375692.1
ENST00000420078.1
CLCNKA
chloride channel, voltage-sensitive Ka
chr4_+_111397216 0.90 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr1_+_161087873 0.88 ENST00000368009.2
ENST00000368007.4
ENST00000368008.1
ENST00000392190.5
NIT1
nitrilase 1
chr16_+_28858004 0.86 ENST00000322610.8
SH2B1
SH2B adaptor protein 1
chr5_+_152870734 0.78 ENST00000521843.2
GRIA1
glutamate receptor, ionotropic, AMPA 1
chrX_+_70364667 0.77 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chrX_+_53078273 0.75 ENST00000332582.4
GPR173
G protein-coupled receptor 173
chr6_+_31540056 0.65 ENST00000418386.2
LTA
lymphotoxin alpha
chr7_-_37026108 0.59 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr10_-_49701686 0.56 ENST00000417247.2
ARHGAP22
Rho GTPase activating protein 22
chr19_+_10563567 0.53 ENST00000344979.3
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_100315613 0.50 ENST00000361915.3
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr14_+_55033815 0.49 ENST00000554335.1
SAMD4A
sterile alpha motif domain containing 4A
chr4_-_66535653 0.49 ENST00000354839.4
ENST00000432638.2
EPHA5
EPH receptor A5
chr11_-_59612969 0.44 ENST00000541311.1
ENST00000257248.2
GIF
gastric intrinsic factor (vitamin B synthesis)
chr1_+_1567546 0.44 ENST00000378675.3
MMP23B
matrix metallopeptidase 23B
chr5_+_140514782 0.40 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr1_-_94586651 0.33 ENST00000535735.1
ENST00000370225.3
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr19_-_11450249 0.31 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr4_-_109090106 0.23 ENST00000379951.2
LEF1
lymphoid enhancer-binding factor 1
chrX_+_118425471 0.22 ENST00000428222.1
RP5-1139I1.1
RP5-1139I1.1
chr14_-_65409438 0.14 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr1_+_65613217 0.10 ENST00000545314.1
AK4
adenylate kinase 4
chr1_+_16348497 0.09 ENST00000439316.2
CLCNKA
chloride channel, voltage-sensitive Ka
chr17_-_76274572 0.07 ENST00000374945.1
RP11-219G17.4
RP11-219G17.4
chr8_-_144623595 0.06 ENST00000262577.5
ZC3H3
zinc finger CCCH-type containing 3
chr8_-_82754427 0.05 ENST00000353788.4
ENST00000520618.1
ENST00000518183.1
ENST00000396330.2
ENST00000519119.1
ENST00000345957.4
SNX16
sorting nexin 16
chr1_+_233749739 0.00 ENST00000366621.3
KCNK1
potassium channel, subfamily K, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 16.0 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
2.8 8.3 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
1.9 5.8 GO:0071284 cellular response to lead ion(GO:0071284)
1.8 15.9 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.6 6.5 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
1.6 6.3 GO:0007538 primary sex determination(GO:0007538)
1.5 9.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
1.5 6.0 GO:0061743 motor learning(GO:0061743)
1.5 7.5 GO:0046340 diacylglycerol catabolic process(GO:0046340)
1.5 16.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.5 7.3 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
1.3 5.4 GO:0002317 plasma cell differentiation(GO:0002317)
1.1 5.3 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
1.0 14.3 GO:0042738 exogenous drug catabolic process(GO:0042738)
1.0 4.1 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.0 4.8 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.9 14.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.9 3.7 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.9 22.7 GO:0001502 cartilage condensation(GO:0001502)
0.9 8.8 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.9 2.6 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.9 13.0 GO:0006751 glutathione catabolic process(GO:0006751)
0.8 2.4 GO:0048867 stem cell fate determination(GO:0048867)
0.7 6.7 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.7 2.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.6 7.7 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.6 4.4 GO:0015824 proline transport(GO:0015824)
0.6 5.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.6 2.8 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.5 2.7 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.5 25.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.5 3.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.5 5.8 GO:0008272 sulfate transport(GO:0008272)
0.4 2.9 GO:0015870 acetylcholine transport(GO:0015870)
0.4 10.5 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.4 1.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.4 3.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.4 7.4 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.3 19.5 GO:0010039 response to iron ion(GO:0010039)
0.3 1.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 10.8 GO:0046688 response to copper ion(GO:0046688)
0.3 3.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3 0.7 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.3 5.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 4.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.3 5.1 GO:0043586 tongue development(GO:0043586)
0.2 6.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 1.8 GO:0061042 vascular wound healing(GO:0061042)
0.2 11.6 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.2 0.8 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 7.6 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.2 1.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.2 0.9 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 5.0 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 7.0 GO:0051646 mitochondrion localization(GO:0051646)
0.1 2.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.9 GO:0044254 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.1 7.1 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 3.7 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 5.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 5.3 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 4.1 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 2.5 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 12.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 2.5 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.4 GO:0006824 cobalt ion transport(GO:0006824)
0.1 4.0 GO:0001895 retina homeostasis(GO:0001895)
0.1 0.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 1.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 3.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 3.6 GO:0030574 collagen catabolic process(GO:0030574)
0.0 11.0 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 4.2 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 1.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 14.2 GO:0001558 regulation of cell growth(GO:0001558)
0.0 7.7 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 5.2 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 2.9 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 3.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 6.5 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 1.1 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.9 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 0.5 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 1.5 GO:0051924 regulation of calcium ion transport(GO:0051924)
0.0 2.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 11.0 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 1.8 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 16.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
3.9 19.5 GO:0005602 complement component C1 complex(GO:0005602)
1.1 3.2 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
1.0 6.7 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.8 8.1 GO:0097427 microtubule bundle(GO:0097427)
0.6 8.6 GO:0043083 synaptic cleft(GO:0043083)
0.6 2.9 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.4 13.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.4 6.5 GO:0031045 dense core granule(GO:0031045)
0.3 3.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 4.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 3.9 GO:0043194 axon initial segment(GO:0043194)
0.2 5.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 1.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 2.7 GO:0097227 sperm annulus(GO:0097227)
0.2 16.3 GO:0005811 lipid particle(GO:0005811)
0.2 23.4 GO:0005796 Golgi lumen(GO:0005796)
0.2 1.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 1.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 2.4 GO:0005869 dynactin complex(GO:0005869)
0.2 0.8 GO:0044308 axonal spine(GO:0044308)
0.1 3.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 2.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 2.1 GO:0042599 lamellar body(GO:0042599)
0.1 22.1 GO:0072562 blood microparticle(GO:0072562)
0.1 11.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.3 GO:0032059 bleb(GO:0032059)
0.1 10.7 GO:0042641 actomyosin(GO:0042641)
0.1 5.6 GO:0005581 collagen trimer(GO:0005581)
0.1 3.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 38.6 GO:0005925 focal adhesion(GO:0005925)
0.1 2.9 GO:0001533 cornified envelope(GO:0001533)
0.1 15.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 0.9 GO:0034709 methylosome(GO:0034709)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 7.7 GO:0005875 microtubule associated complex(GO:0005875)
0.0 6.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.7 GO:0045095 keratin filament(GO:0045095)
0.0 17.9 GO:0016607 nuclear speck(GO:0016607)
0.0 7.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 5.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 40.0 GO:0005615 extracellular space(GO:0005615)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 3.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 5.3 GO:0005635 nuclear envelope(GO:0005635)
0.0 3.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 16.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
3.5 14.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
2.5 7.5 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
2.1 16.5 GO:0001849 complement component C1q binding(GO:0001849)
1.9 5.8 GO:0032767 copper-dependent protein binding(GO:0032767)
1.2 10.8 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.1 8.8 GO:0004465 lipoprotein lipase activity(GO:0004465)
1.0 18.4 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
1.0 6.7 GO:0097643 amylin receptor activity(GO:0097643)
0.7 5.8 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.7 2.9 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.7 9.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.7 2.6 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.6 3.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.6 3.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.6 7.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.6 24.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.6 3.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.6 4.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.6 2.8 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.5 7.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.5 4.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.4 10.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.4 4.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3 3.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3 5.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 7.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 2.5 GO:0000182 rDNA binding(GO:0000182)
0.3 3.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.2 7.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 2.5 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 3.6 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 3.2 GO:0045499 chemorepellent activity(GO:0045499)
0.2 4.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 5.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 18.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 4.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 3.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.2 6.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 6.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 7.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 6.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 32.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 31.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 0.8 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 4.1 GO:0030507 spectrin binding(GO:0030507)
0.1 6.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 5.0 GO:0030145 manganese ion binding(GO:0030145)
0.1 3.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 5.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.9 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 2.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 4.3 GO:0005179 hormone activity(GO:0005179)
0.0 6.3 GO:0003823 antigen binding(GO:0003823)
0.0 3.6 GO:0005518 collagen binding(GO:0005518)
0.0 4.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 2.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 2.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 7.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 21.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.9 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 1.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 5.4 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 10.7 GO:0008270 zinc ion binding(GO:0008270)
0.0 6.6 GO:0003779 actin binding(GO:0003779)
0.0 6.1 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.3 37.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.3 18.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 15.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 7.4 PID S1P S1P3 PATHWAY S1P3 pathway
0.2 30.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 8.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 7.0 PID NOTCH PATHWAY Notch signaling pathway
0.1 9.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 6.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 4.1 PID BMP PATHWAY BMP receptor signaling
0.1 4.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 5.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 19.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.6 16.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.8 14.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.7 16.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.6 15.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 8.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4 4.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.4 25.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.4 13.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.3 4.8 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.3 4.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 15.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.3 7.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 3.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 5.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.9 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 11.4 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 4.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 4.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 3.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 8.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 6.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.0 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 1.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 3.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 2.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 8.1 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA