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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for ZNF263

Z-value: 0.76

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Transcription factors associated with ZNF263

Gene Symbol Gene ID Gene Info
ENSG00000006194.6 zinc finger protein 263

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF263hg19_v2_chr16_+_3313791_3313834-0.161.8e-02Click!

Activity profile of ZNF263 motif

Sorted Z-values of ZNF263 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_137801160 26.01 ENST00000239938.4
early growth response 1
chr12_+_53773944 25.60 ENST00000551969.1
ENST00000327443.4
Sp1 transcription factor
chr14_-_27066960 18.74 ENST00000539517.2
neuro-oncological ventral antigen 1
chr13_-_88323218 18.06 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500 host gene (non-protein coding)
chr1_+_6845384 17.23 ENST00000303635.7
calmodulin binding transcription activator 1
chr12_-_6798616 16.93 ENST00000355772.4
ENST00000417772.3
ENST00000396801.3
ENST00000396799.2
zinc finger protein 384
chrX_+_24167828 15.14 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
zinc finger protein, X-linked
chr14_-_27066636 14.41 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
neuro-oncological ventral antigen 1
chr12_-_6798523 14.27 ENST00000319770.3
zinc finger protein 384
chr12_-_91573132 14.23 ENST00000550563.1
ENST00000546370.1
decorin
chr14_+_95078714 14.03 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_-_6798410 13.98 ENST00000361959.3
ENST00000436774.2
ENST00000544482.1
zinc finger protein 384
chr7_-_150038704 13.50 ENST00000466675.1
ENST00000482669.1
ENST00000467793.1
ENST00000223271.3
retinoic acid receptor responder (tazarotene induced) 2
chr19_+_55587266 13.25 ENST00000201647.6
ENST00000540810.1
EPS8-like 1
chr12_+_6930813 12.34 ENST00000428545.2
G protein-coupled receptor 162
chr8_+_26435359 12.21 ENST00000311151.5
dihydropyrimidinase-like 2
chr14_-_81687197 12.02 ENST00000553612.1
general transcription factor IIA, 1, 19/37kDa
chr12_+_6930703 11.62 ENST00000311268.3
G protein-coupled receptor 162
chr3_-_127542051 11.22 ENST00000398104.1
monoglyceride lipase
chr12_-_91573249 11.21 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr22_+_29876197 10.85 ENST00000310624.6
neurofilament, heavy polypeptide
chr12_+_6930964 10.28 ENST00000382315.3
G protein-coupled receptor 162
chr12_+_54332535 10.20 ENST00000243056.3
homeobox C13
chr17_-_27278304 10.16 ENST00000577226.1
PHD finger protein 12
chr10_-_79397391 9.98 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr1_+_160085501 9.93 ENST00000361216.3
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr3_-_133614597 9.74 ENST00000285208.4
ENST00000460865.3
RAB6B, member RAS oncogene family
chr17_+_77020224 9.56 ENST00000339142.2
C1q and tumor necrosis factor related protein 1
chr5_-_149535421 9.44 ENST00000261799.4
platelet-derived growth factor receptor, beta polypeptide
chr15_-_90358048 9.42 ENST00000300060.6
ENST00000560137.1
alanyl (membrane) aminopeptidase
chr14_-_60337684 9.37 ENST00000267484.5
reticulon 1
chr7_+_94023873 9.31 ENST00000297268.6
collagen, type I, alpha 2
chr18_-_51750948 9.29 ENST00000583046.1
ENST00000398398.2
methyl-CpG binding domain protein 2
chr10_-_79397316 9.22 ENST00000372421.5
ENST00000457953.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr12_-_91573316 9.11 ENST00000393155.1
decorin
chr3_-_133614421 9.10 ENST00000543906.1
RAB6B, member RAS oncogene family
chr20_+_19193269 9.05 ENST00000328041.6
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr12_+_53443680 9.01 ENST00000314250.6
ENST00000451358.1
tensin like C1 domain containing phosphatase (tensin 2)
chr17_+_77020325 9.00 ENST00000311661.4
C1q and tumor necrosis factor related protein 1
chr10_-_79397202 8.93 ENST00000372437.1
ENST00000372408.2
ENST00000372403.4
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr1_+_209859510 8.83 ENST00000367028.2
ENST00000261465.1
hydroxysteroid (11-beta) dehydrogenase 1
chr4_-_5891918 8.74 ENST00000512574.1
collapsin response mediator protein 1
chr11_-_113746212 8.69 ENST00000537642.1
ENST00000537706.1
ENST00000544750.1
ENST00000260188.5
ENST00000540925.1
ubiquitin specific peptidase 28
chr3_-_127542021 8.62 ENST00000434178.2
monoglyceride lipase
chr15_-_63674034 8.55 ENST00000344366.3
ENST00000422263.2
carbonic anhydrase XII
chr11_-_66725837 8.46 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
pyruvate carboxylase
chr15_-_71146480 8.41 ENST00000299213.8
La ribonucleoprotein domain family, member 6
chr11_-_66336060 8.32 ENST00000310325.5
cathepsin F
chr14_+_75746340 8.30 ENST00000555686.1
ENST00000555672.1
FBJ murine osteosarcoma viral oncogene homolog
chr19_+_36359341 8.23 ENST00000221891.4
amyloid beta (A4) precursor-like protein 1
chr11_+_695380 8.16 ENST00000397510.3
transmembrane protein 80
chr8_+_22462532 8.15 ENST00000389279.3
cell cycle and apoptosis regulator 2
chr18_-_56940611 8.06 ENST00000256852.7
ENST00000334889.3
retina and anterior neural fold homeobox
chr3_-_120170052 8.03 ENST00000295633.3
follistatin-like 1
chr2_+_74120094 7.94 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
actin, gamma 2, smooth muscle, enteric
chrX_+_153237740 7.82 ENST00000369982.4
transmembrane protein 187
chr7_-_38670957 7.78 ENST00000325590.5
ENST00000428293.2
amphiphysin
chr14_-_23834411 7.78 ENST00000429593.2
embryonal Fyn-associated substrate
chr11_-_71639670 7.74 ENST00000533047.1
ENST00000529844.1
Putative short transient receptor potential channel 2-like protein
chr11_-_113746277 7.73 ENST00000003302.4
ENST00000545540.1
ubiquitin specific peptidase 28
chr6_+_31949801 7.66 ENST00000428956.2
ENST00000498271.1
complement component 4A (Rodgers blood group)
chr2_-_216300784 7.63 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
fibronectin 1
chrX_+_103031421 7.62 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
proteolipid protein 1
chrX_-_110039286 7.58 ENST00000434224.1
chordin-like 1
chrY_+_2803322 7.55 ENST00000383052.1
ENST00000155093.3
ENST00000449237.1
ENST00000443793.1
zinc finger protein, Y-linked
chr12_+_53443963 7.52 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
tensin like C1 domain containing phosphatase (tensin 2)
chr6_+_31982539 7.50 ENST00000435363.2
ENST00000425700.2
complement component 4B (Chido blood group)
chrX_+_103031758 7.44 ENST00000303958.2
ENST00000361621.2
proteolipid protein 1
chr14_+_57857262 7.41 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr6_-_31514333 7.36 ENST00000376151.4
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr10_-_118502070 7.34 ENST00000369209.3
heat shock 70kDa protein 12A
chr10_+_76586348 7.34 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
K(lysine) acetyltransferase 6B
chrX_-_110039038 7.33 ENST00000372042.1
ENST00000482160.1
ENST00000444321.2
ENST00000218054.4
chordin-like 1
chr4_-_153457197 7.31 ENST00000281708.4
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chrX_+_23352133 7.29 ENST00000379361.4
patched domain containing 1
chr6_-_31514516 7.22 ENST00000303892.5
ENST00000483251.1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr9_+_126773880 7.17 ENST00000373615.4
LIM homeobox 2
chr11_-_6341844 7.17 ENST00000303927.3
protein kinase C, delta binding protein
chr17_-_2206801 7.15 ENST00000544865.1
SMG6 nonsense mediated mRNA decay factor
chr10_+_123872483 7.14 ENST00000369001.1
transforming, acidic coiled-coil containing protein 2
chr6_-_169654139 7.09 ENST00000366787.3
thrombospondin 2
chr3_+_35681081 7.07 ENST00000428373.1
cAMP-regulated phosphoprotein, 21kDa
chr1_+_36023035 7.06 ENST00000373253.3
neurochondrin
chr3_-_127541679 7.05 ENST00000265052.5
monoglyceride lipase
chr5_-_146833485 6.98 ENST00000398514.3
dihydropyrimidinase-like 3
chr19_-_38714847 6.93 ENST00000420980.2
ENST00000355526.4
D4, zinc and double PHD fingers family 1
chr22_+_17082732 6.92 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
transmembrane phosphatase with tensin homology pseudogene 1
chr19_-_7968427 6.89 ENST00000539278.1
Uncharacterized protein
chr11_-_73309228 6.86 ENST00000356467.4
ENST00000064778.4
family with sequence similarity 168, member A
chr8_+_26371763 6.86 ENST00000521913.1
dihydropyrimidinase-like 2
chr2_-_50574856 6.85 ENST00000342183.5
neurexin 1
chr19_-_47975417 6.80 ENST00000236877.6
solute carrier family 8 (sodium/calcium exchanger), member 2
chr1_+_25944341 6.79 ENST00000263979.3
mannosidase, alpha, class 1C, member 1
chr20_+_54933971 6.75 ENST00000371384.3
ENST00000437418.1
family with sequence similarity 210, member B
chrX_+_24167746 6.65 ENST00000428571.1
ENST00000539115.1
zinc finger protein, X-linked
chr7_+_26438187 6.63 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
chr19_+_58790314 6.63 ENST00000196548.5
ENST00000608843.1
Zinc finger protein 8
zinc finger protein 8
chrX_-_47479246 6.61 ENST00000295987.7
ENST00000340666.4
synapsin I
chr11_-_6341724 6.60 ENST00000530979.1
protein kinase C, delta binding protein
chr13_-_46626847 6.60 ENST00000242848.4
ENST00000282007.3
zinc finger CCCH-type containing 13
chr11_-_64490634 6.53 ENST00000377559.3
ENST00000265459.6
neurexin 2
chr4_+_55524085 6.52 ENST00000412167.2
ENST00000288135.5
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr5_+_74807886 6.52 ENST00000514296.1
polymerase (DNA directed) kappa
chr3_+_189507460 6.51 ENST00000434928.1
tumor protein p63
chr17_-_34890759 6.51 ENST00000431794.3
myosin XIX
chr10_+_38299546 6.43 ENST00000374618.3
ENST00000432900.2
ENST00000458705.2
ENST00000469037.2
zinc finger protein 33A
chr5_-_11904100 6.40 ENST00000359640.2
catenin (cadherin-associated protein), delta 2
chr2_-_152955213 6.39 ENST00000427385.1
calcium channel, voltage-dependent, beta 4 subunit
chr2_-_26205340 6.39 ENST00000264712.3
kinesin family member 3C
chr8_+_22462145 6.38 ENST00000308511.4
ENST00000523801.1
ENST00000521301.1
cell cycle and apoptosis regulator 2
chr7_-_143059780 6.35 ENST00000409578.1
ENST00000409346.1
family with sequence similarity 131, member B
chr5_-_11904152 6.33 ENST00000304623.8
ENST00000458100.2
catenin (cadherin-associated protein), delta 2
chr1_+_202317815 6.26 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr8_+_22022653 6.23 ENST00000354870.5
ENST00000397816.3
ENST00000306349.8
bone morphogenetic protein 1
chr12_-_106641728 6.22 ENST00000378026.4
cytoskeleton-associated protein 4
chr1_-_57889687 6.22 ENST00000371236.2
ENST00000371230.1
Dab, reelin signal transducer, homolog 1 (Drosophila)
chr13_-_110959478 6.21 ENST00000543140.1
ENST00000375820.4
collagen, type IV, alpha 1
chr5_-_134914673 6.13 ENST00000512158.1
chemokine (C-X-C motif) ligand 14
chr11_-_62494821 6.06 ENST00000301785.5
heterogeneous nuclear ribonucleoprotein U-like 2
chr2_-_152955537 6.06 ENST00000201943.5
ENST00000539935.1
calcium channel, voltage-dependent, beta 4 subunit
chr14_-_93799360 6.06 ENST00000334746.5
ENST00000554565.1
ENST00000298896.3
BTB (POZ) domain containing 7
chr15_-_57025759 6.00 ENST00000267807.7
zinc finger protein 280D
chr11_-_7041466 6.00 ENST00000536068.1
ENST00000278314.4
zinc finger protein 214
chr1_+_36023370 5.97 ENST00000356090.4
ENST00000373243.2
neurochondrin
chr5_+_173472607 5.97 ENST00000303177.3
ENST00000519867.1
Neuron-specific protein family member 2
chr1_-_241520525 5.94 ENST00000366565.1
regulator of G-protein signaling 7
chr6_-_32077100 5.93 ENST00000375244.3
ENST00000375247.2
tenascin XB
chr19_-_51504852 5.92 ENST00000391806.2
ENST00000347619.4
ENST00000291726.7
ENST00000320838.5
kallikrein-related peptidase 8
chr1_+_162039558 5.89 ENST00000530878.1
ENST00000361897.5
nitric oxide synthase 1 (neuronal) adaptor protein
chr18_+_46065483 5.89 ENST00000382998.4
CBP80/20-dependent translation initiation factor
chr9_+_130911770 5.82 ENST00000372998.1
lipocalin 2
chr7_-_19157248 5.79 ENST00000242261.5
twist family bHLH transcription factor 1
chr15_-_83378638 5.78 ENST00000261722.3
adaptor-related protein complex 3, beta 2 subunit
chr15_-_83378611 5.76 ENST00000542200.1
adaptor-related protein complex 3, beta 2 subunit
chr9_-_122131696 5.74 ENST00000373964.2
ENST00000265922.3
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr4_+_3768075 5.74 ENST00000509482.1
ENST00000330055.5
adrenoceptor alpha 2C
chr16_-_31085514 5.73 ENST00000300849.4
zinc finger protein 668
chr17_-_34890709 5.71 ENST00000544606.1
myosin XIX
chr19_+_50016411 5.67 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
Fc fragment of IgG, receptor, transporter, alpha
chrX_-_17879356 5.67 ENST00000331511.1
ENST00000415486.3
ENST00000545871.1
ENST00000451717.1
retinoic acid induced 2
chr2_-_51259292 5.66 ENST00000401669.2
neurexin 1
chr13_+_110959598 5.63 ENST00000360467.5
collagen, type IV, alpha 2
chr10_+_18429606 5.59 ENST00000324631.7
ENST00000352115.6
ENST00000377328.1
calcium channel, voltage-dependent, beta 2 subunit
chr15_-_77712477 5.58 ENST00000560626.2
pseudopodium-enriched atypical kinase 1
chr2_+_203776937 5.58 ENST00000402905.3
ENST00000414490.1
ENST00000431787.1
ENST00000444724.1
ENST00000414857.1
ENST00000430899.1
ENST00000445120.1
ENST00000441569.1
ENST00000432024.1
ENST00000443740.1
ENST00000414439.1
ENST00000428585.1
ENST00000545253.1
ENST00000545262.1
ENST00000447539.1
ENST00000456821.2
ENST00000434998.1
ENST00000320443.8
calcium responsive transcription factor
chr10_+_18429671 5.53 ENST00000282343.8
calcium channel, voltage-dependent, beta 2 subunit
chr16_-_75590114 5.47 ENST00000568377.1
ENST00000565067.1
ENST00000258173.6
transmembrane protein 231
chr3_-_149688655 5.45 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
profilin 2
chr17_+_60704762 5.45 ENST00000303375.5
mannose receptor, C type 2
chr3_-_149688896 5.42 ENST00000239940.7
profilin 2
chr19_+_7968728 5.40 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
mitogen-activated protein kinase kinase 7
chr11_-_17565854 5.37 ENST00000005226.7
Usher syndrome 1C (autosomal recessive, severe)
chr12_+_119616447 5.36 ENST00000281938.2
heat shock 22kDa protein 8
chr5_-_95297534 5.36 ENST00000513343.1
ENST00000431061.2
elongation factor, RNA polymerase II, 2
chr17_-_40333150 5.32 ENST00000264661.3
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr15_+_91427691 5.30 ENST00000559355.1
ENST00000394302.1
feline sarcoma oncogene
chr17_+_73750699 5.27 ENST00000584939.1
integrin, beta 4
chr2_+_111490161 5.26 ENST00000340561.4
acyl-CoA oxidase-like
chr9_-_113341985 5.24 ENST00000374469.1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr11_-_46722117 5.23 ENST00000311956.4
Rho GTPase activating protein 1
chr10_-_53459319 5.23 ENST00000331173.4
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chrX_+_110187513 5.20 ENST00000446737.1
ENST00000425146.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr17_-_40333099 5.20 ENST00000607371.1
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr1_+_150480576 5.20 ENST00000346569.6
extracellular matrix protein 1
chr19_-_13617037 5.20 ENST00000360228.5
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr12_+_57984965 5.20 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr13_-_44361025 5.19 ENST00000261488.6
ecto-NOX disulfide-thiol exchanger 1
chr3_-_50605150 5.16 ENST00000357203.3
chromosome 3 open reading frame 18
chr15_-_64338521 5.15 ENST00000457488.1
ENST00000558069.1
death-associated protein kinase 2
chr3_-_50605077 5.14 ENST00000426034.1
ENST00000441239.1
chromosome 3 open reading frame 18
chr1_-_157108266 5.13 ENST00000326786.4
ets variant 3
chr19_+_36249057 5.08 ENST00000301165.5
ENST00000536950.1
ENST00000537459.1
ENST00000421853.2
chromosome 19 open reading frame 55
chr1_-_144932316 5.07 ENST00000313431.9
phosphodiesterase 4D interacting protein
chr2_-_51259641 5.04 ENST00000406316.2
ENST00000405581.1
neurexin 1
chr3_+_184053703 5.03 ENST00000450976.1
ENST00000418281.1
ENST00000340957.5
ENST00000433578.1
family with sequence similarity 131, member A
chr2_-_51259528 5.02 ENST00000404971.1
neurexin 1
chr13_+_31191920 5.00 ENST00000255304.4
ubiquitin specific peptidase like 1
chr17_+_34958001 5.00 ENST00000250156.7
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr16_-_68482440 4.99 ENST00000219334.5
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr2_-_51259229 4.98 ENST00000405472.3
neurexin 1
chr1_+_25943959 4.93 ENST00000374332.4
mannosidase, alpha, class 1C, member 1
chr13_-_33002151 4.92 ENST00000495479.1
ENST00000343281.4
ENST00000464470.1
ENST00000380139.4
ENST00000380133.2
NEDD4 binding protein 2-like 1
chr4_+_157997273 4.91 ENST00000541722.1
ENST00000512619.1
glycine receptor, beta
chrX_-_47509887 4.89 ENST00000247161.3
ENST00000592066.1
ENST00000376983.3
ELK1, member of ETS oncogene family
chrX_+_16804544 4.85 ENST00000380122.5
ENST00000398155.4
taxilin gamma
chr16_-_88923285 4.83 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
galactosamine (N-acetyl)-6-sulfate sulfatase
chr16_-_28550320 4.82 ENST00000395641.2
nuclear protein, transcriptional regulator, 1
chr3_-_178789993 4.81 ENST00000432729.1
zinc finger, matrin-type 3
chr19_+_48216600 4.80 ENST00000263277.3
ENST00000538399.1
EH-domain containing 2
chr11_+_46316677 4.78 ENST00000534787.1
cAMP responsive element binding protein 3-like 1
chr2_-_89157161 4.78 ENST00000390237.2
immunoglobulin kappa constant
chr4_-_7941596 4.77 ENST00000420658.1
ENST00000358461.2
actin filament associated protein 1
chr7_+_150498610 4.77 ENST00000461345.1
transmembrane protein 176A
chr7_+_55086703 4.76 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
epidermal growth factor receptor
chr3_+_38323785 4.75 ENST00000466887.1
ENST00000448498.1
solute carrier family 22, member 14
chr3_+_167453493 4.73 ENST00000295777.5
ENST00000472747.2
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr1_-_6321035 4.73 ENST00000377893.2
G protein-coupled receptor 153
chr19_+_45349432 4.73 ENST00000252485.4
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr1_+_224803995 4.71 ENST00000272133.3
cornichon family AMPA receptor auxiliary protein 3
chr1_+_36690011 4.71 ENST00000354618.5
ENST00000469141.2
ENST00000478853.1
thyroid hormone receptor associated protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF263

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.7 26.0 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759) regulation of progesterone biosynthetic process(GO:2000182)
4.7 9.4 GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
4.6 18.6 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
4.5 27.2 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
4.5 13.5 GO:0061760 antifungal innate immune response(GO:0061760)
4.3 34.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
3.8 26.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
3.7 14.9 GO:0048749 compound eye development(GO:0048749)
3.6 39.9 GO:0034465 response to carbon monoxide(GO:0034465)
3.6 10.9 GO:0048936 neurofilament bundle assembly(GO:0033693) peripheral nervous system neuron axonogenesis(GO:0048936)
3.3 3.3 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
2.9 8.7 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
2.9 34.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
2.9 8.6 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
2.8 8.5 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
2.6 7.7 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
2.5 7.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
2.5 12.7 GO:0070384 Harderian gland development(GO:0070384)
2.4 9.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
2.4 9.7 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
2.3 4.6 GO:0050771 negative regulation of axonogenesis(GO:0050771)
2.2 6.5 GO:0048170 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162) positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
2.1 6.2 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
2.1 6.2 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
2.1 12.4 GO:0055064 chloride ion homeostasis(GO:0055064)
2.0 6.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
2.0 9.9 GO:0051946 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
2.0 11.9 GO:0090131 mesenchyme migration(GO:0090131)
2.0 9.9 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
2.0 11.7 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
1.9 5.8 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
1.9 17.0 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
1.8 5.5 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
1.8 5.4 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
1.7 5.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
1.6 8.2 GO:0071873 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
1.6 4.9 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
1.6 6.5 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.6 3.2 GO:1903978 regulation of microglial cell activation(GO:1903978)
1.6 6.4 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
1.6 12.7 GO:0008090 retrograde axonal transport(GO:0008090)
1.6 4.8 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
1.5 4.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
1.5 4.5 GO:0014016 neuroblast differentiation(GO:0014016)
1.5 4.5 GO:0007538 primary sex determination(GO:0007538)
1.5 10.4 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.5 11.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.5 7.3 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
1.5 18.9 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.4 5.7 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
1.4 14.0 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
1.3 10.8 GO:0001661 conditioned taste aversion(GO:0001661)
1.3 4.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.3 9.3 GO:0097091 synaptic vesicle clustering(GO:0097091)
1.3 3.9 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
1.3 15.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
1.3 1.3 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
1.3 5.1 GO:0000103 sulfate assimilation(GO:0000103)
1.2 11.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
1.2 3.7 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
1.2 2.4 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
1.1 4.5 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
1.1 14.5 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
1.1 4.4 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
1.1 15.5 GO:0035878 nail development(GO:0035878)
1.1 3.3 GO:0021586 pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
1.1 4.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
1.1 8.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.0 2.1 GO:0048636 positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
1.0 6.3 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.0 7.3 GO:0032472 Golgi calcium ion transport(GO:0032472)
1.0 3.1 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
1.0 2.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
1.0 11.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
1.0 3.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
1.0 3.0 GO:0072092 ureteric bud invasion(GO:0072092)
1.0 11.1 GO:0043589 skin morphogenesis(GO:0043589)
1.0 18.9 GO:0090140 regulation of mitochondrial fission(GO:0090140)
1.0 2.0 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.0 6.9 GO:0071896 protein localization to adherens junction(GO:0071896)
1.0 3.9 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.9 4.7 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.9 2.8 GO:0009183 ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.9 5.5 GO:0046208 spermine catabolic process(GO:0046208)
0.9 7.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.9 2.7 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.9 10.6 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.9 3.5 GO:0072237 metanephric proximal tubule development(GO:0072237)
0.9 6.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.9 1.8 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.9 2.6 GO:0045925 female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925)
0.9 3.5 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.9 2.6 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.9 5.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.8 3.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.8 5.9 GO:0031642 negative regulation of myelination(GO:0031642)
0.8 2.5 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.8 4.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.8 19.3 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.8 15.0 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.8 9.2 GO:0021978 telencephalon regionalization(GO:0021978)
0.8 11.2 GO:0021794 thalamus development(GO:0021794)
0.8 2.4 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.8 0.8 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.8 11.0 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.8 1.6 GO:0032499 detection of peptidoglycan(GO:0032499)
0.8 4.7 GO:0001880 Mullerian duct regression(GO:0001880)
0.8 3.1 GO:0060214 endocardium formation(GO:0060214)
0.8 3.1 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.8 2.3 GO:1903860 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.8 7.6 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.7 2.2 GO:0048378 vacuolar phosphate transport(GO:0007037) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.7 3.0 GO:1900166 glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.7 3.0 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.7 2.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.7 2.2 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.7 11.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.7 4.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.7 0.7 GO:0061312 BMP signaling pathway involved in heart development(GO:0061312)
0.7 2.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.7 5.6 GO:0035865 cellular response to potassium ion(GO:0035865)
0.7 2.8 GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635) negative regulation of Wnt protein secretion(GO:0061358)
0.7 2.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.7 12.7 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.7 2.0 GO:1990029 pulmonary valve formation(GO:0003193) atrial ventricular junction remodeling(GO:0003294) foramen ovale closure(GO:0035922) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.7 2.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.7 3.3 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.7 3.3 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.7 3.3 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.7 2.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.6 1.9 GO:0000189 MAPK import into nucleus(GO:0000189)
0.6 7.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.6 1.3 GO:0061074 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.6 12.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.6 1.9 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.6 1.9 GO:0015680 intracellular copper ion transport(GO:0015680)
0.6 4.3 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.6 2.4 GO:0045715 transforming growth factor-beta secretion(GO:0038044) negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.6 8.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.6 14.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.6 6.0 GO:0048102 autophagic cell death(GO:0048102)
0.6 4.8 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.6 1.8 GO:0001172 transcription, RNA-templated(GO:0001172)
0.6 10.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.6 3.5 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.6 8.8 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.6 4.7 GO:0070475 rRNA base methylation(GO:0070475)
0.6 3.5 GO:0070560 protein secretion by platelet(GO:0070560)
0.6 5.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.6 1.7 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.6 1.7 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.6 3.4 GO:0048149 behavioral response to ethanol(GO:0048149)
0.6 1.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.6 6.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.6 4.5 GO:0070779 sulfur amino acid transport(GO:0000101) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.5 2.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.5 3.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.5 2.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.5 1.6 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.5 7.3 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.5 2.6 GO:0032494 response to peptidoglycan(GO:0032494)
0.5 3.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.5 3.1 GO:0009624 response to nematode(GO:0009624)
0.5 3.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.5 1.5 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.5 11.2 GO:0001502 cartilage condensation(GO:0001502)
0.5 3.0 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.5 2.5 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.5 5.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.5 9.0 GO:0051764 actin crosslink formation(GO:0051764)
0.5 3.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.5 4.9 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.5 2.9 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.5 3.4 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.5 5.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.5 1.4 GO:0036071 N-glycan fucosylation(GO:0036071)
0.5 1.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.5 1.4 GO:0007500 mesodermal cell fate determination(GO:0007500) negative regulation of muscle hyperplasia(GO:0014740) cellular response to cycloheximide(GO:0071409)
0.5 2.7 GO:0051639 actin filament network formation(GO:0051639)
0.5 1.8 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.4 2.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.4 6.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.4 1.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.4 1.3 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.4 2.6 GO:0007288 sperm axoneme assembly(GO:0007288)
0.4 2.6 GO:0006196 AMP catabolic process(GO:0006196)
0.4 3.9 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.4 8.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.4 14.6 GO:0090383 phagosome acidification(GO:0090383)
0.4 2.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.4 1.3 GO:0032900 regulation of neurotrophin production(GO:0032899) negative regulation of neurotrophin production(GO:0032900)
0.4 2.5 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.4 6.4 GO:0097320 membrane tubulation(GO:0097320)
0.4 2.5 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.4 4.1 GO:0015889 cobalamin transport(GO:0015889)
0.4 3.7 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.4 4.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.4 4.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.4 1.6 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.4 1.6 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.4 2.0 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.4 2.7 GO:0060033 anatomical structure regression(GO:0060033)
0.4 5.0 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.4 1.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.4 1.5 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.4 1.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.4 2.7 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.4 2.7 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.4 3.0 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.4 2.7 GO:0035897 proteolysis in other organism(GO:0035897)
0.4 1.9 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.4 7.8 GO:0033622 integrin activation(GO:0033622)
0.4 1.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.4 1.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.3 5.6 GO:0030509 BMP signaling pathway(GO:0030509)
0.3 2.4 GO:0090382 phagosome maturation(GO:0090382)
0.3 3.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.3 3.8 GO:0071285 cellular response to lithium ion(GO:0071285)
0.3 4.8 GO:2000194 regulation of female gonad development(GO:2000194)
0.3 1.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.3 2.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.3 5.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.3 4.0 GO:0031167 rRNA methylation(GO:0031167)
0.3 1.7 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.3 7.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 1.3 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.3 1.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 3.0 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.3 2.0 GO:0071625 vocalization behavior(GO:0071625)
0.3 1.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.3 6.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.3 6.5 GO:0006853 carnitine shuttle(GO:0006853)
0.3 13.6 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.3 1.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.3 12.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.3 1.6 GO:0016240 autophagosome docking(GO:0016240)
0.3 4.4 GO:0030500 regulation of bone mineralization(GO:0030500)
0.3 6.2 GO:0071420 cellular response to histamine(GO:0071420)
0.3 1.2 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.3 2.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.3 7.9 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.3 1.7 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.3 3.7 GO:0015732 prostaglandin transport(GO:0015732)
0.3 0.8 GO:0072007 mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.3 2.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.3 2.5 GO:0071545 inositol phosphate catabolic process(GO:0071545)
0.3 2.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.3 1.7 GO:0016078 tRNA catabolic process(GO:0016078)
0.3 4.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.3 3.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.3 4.1 GO:0035810 positive regulation of urine volume(GO:0035810)
0.3 1.9 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.3 3.5 GO:0006273 lagging strand elongation(GO:0006273)
0.3 0.8 GO:0035524 proline transmembrane transport(GO:0035524)
0.3 2.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 0.8 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.3 4.2 GO:0060044 positive regulation of oligodendrocyte differentiation(GO:0048714) negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.3 1.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.3 3.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.3 1.0 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.3 1.0 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.3 2.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.3 3.1 GO:0007266 Rho protein signal transduction(GO:0007266)
0.3 9.5 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.3 2.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.3 0.8 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.3 1.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 1.8 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.2 0.7 GO:0001757 somite specification(GO:0001757)
0.2 1.2 GO:0097338 response to clozapine(GO:0097338)
0.2 19.7 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.2 11.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 3.6 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.2 7.9 GO:0072384 organelle transport along microtubule(GO:0072384)
0.2 6.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 22.2 GO:0030516 regulation of axon extension(GO:0030516)
0.2 1.2 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.2 1.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 3.0 GO:0090527 actin filament reorganization(GO:0090527)
0.2 4.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 1.9 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.2 2.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 12.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 1.8 GO:0046325 negative regulation of glucose import(GO:0046325)
0.2 0.7 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.2 2.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 0.9 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.2 1.1 GO:1901660 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.2 2.4 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.2 6.5 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 2.2 GO:0015868 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.2 0.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 6.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.2 3.7 GO:0008038 neuron recognition(GO:0008038)
0.2 0.8 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 1.0 GO:0048664 neuron fate determination(GO:0048664)
0.2 7.6 GO:0051646 mitochondrion localization(GO:0051646)
0.2 3.5 GO:0051354 negative regulation of oxidoreductase activity(GO:0051354)
0.2 2.9 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.2 1.7 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.2 2.6 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.2 1.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.2 0.9 GO:0016926 protein desumoylation(GO:0016926)
0.2 3.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.2 3.0 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.2 0.5 GO:2001038 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685) regulation of cellular response to drug(GO:2001038)
0.2 2.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.2 2.2 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.2 2.4 GO:0006907 pinocytosis(GO:0006907)
0.2 2.2 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.2 0.5 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.2 1.7 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.2 0.7 GO:0051918 negative regulation of plasminogen activation(GO:0010757) negative regulation of fibrinolysis(GO:0051918)
0.2 3.6 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.2 2.8 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.2 0.5 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 4.5 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.2 4.4 GO:0015695 organic cation transport(GO:0015695)
0.2 3.5 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.2 4.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 3.7 GO:0007398 ectoderm development(GO:0007398)
0.2 2.3 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.2 0.8 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 1.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.2 1.5 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 20.2 GO:0007626 locomotory behavior(GO:0007626)
0.2 5.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.2 1.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.3 GO:1903792 negative regulation of anion transport(GO:1903792)
0.1 5.0 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 2.5 GO:0021549 cerebellum development(GO:0021549)
0.1 2.7 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.1 1.9 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 3.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 1.4 GO:0060009 Sertoli cell development(GO:0060009)
0.1 2.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 1.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 2.8 GO:0014002 astrocyte development(GO:0014002)
0.1 0.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 3.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 2.0 GO:0021854 hypothalamus development(GO:0021854)
0.1 1.6 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 1.3 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 1.8 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313)
0.1 4.3 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 0.8 GO:0045837 negative regulation of mitochondrial membrane potential(GO:0010917) negative regulation of membrane potential(GO:0045837)
0.1 3.4 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 2.7 GO:0003279 cardiac septum development(GO:0003279)
0.1 2.8 GO:0050901 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.1 6.3 GO:0021987 cerebral cortex development(GO:0021987)
0.1 0.6 GO:0048641 regulation of skeletal muscle tissue development(GO:0048641) negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 3.0 GO:0008542 visual learning(GO:0008542)
0.1 0.5 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 1.1 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.1 3.1 GO:0042339 keratan sulfate biosynthetic process(GO:0018146) keratan sulfate metabolic process(GO:0042339)
0.1 14.5 GO:0030449 regulation of complement activation(GO:0030449)
0.1 0.3 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.9 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.6 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 2.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.5 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 1.8 GO:0006379 mRNA cleavage(GO:0006379)
0.1 2.1 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 2.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.5 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1 1.1 GO:0001696 gastric acid secretion(GO:0001696)
0.1 4.3 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 1.1 GO:0042476 odontogenesis(GO:0042476)
0.1 2.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 3.8 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.1 1.4 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.1 2.4 GO:0001947 heart looping(GO:0001947)
0.1 1.6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 1.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.7 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.1 0.6 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.1 4.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 2.0 GO:0007416 synapse assembly(GO:0007416)
0.1 10.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.9 GO:0048754 branching morphogenesis of an epithelial tube(GO:0048754)
0.1 3.0 GO:0016266 O-glycan processing(GO:0016266)
0.1 3.7 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 1.3 GO:0016578 histone deubiquitination(GO:0016578)
0.1 4.3 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 1.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.4 GO:0009642 response to light intensity(GO:0009642)
0.1 0.7 GO:0048477 oogenesis(GO:0048477)
0.1 1.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 4.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.7 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.1 0.4 GO:1904424 regulation of GTP binding(GO:1904424) beta-catenin destruction complex assembly(GO:1904885)
0.1 1.1 GO:0009953 dorsal/ventral pattern formation(GO:0009953)
0.1 1.7 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.1 6.9 GO:0042594 response to starvation(GO:0042594)
0.1 6.7 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 0.9 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 2.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.7 GO:0072678 T cell migration(GO:0072678)
0.1 1.8 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 2.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.5 GO:0030091 protein repair(GO:0030091)
0.1 1.2 GO:0003334 keratinocyte development(GO:0003334)
0.1 3.0 GO:0007422 peripheral nervous system development(GO:0007422)
0.1 7.1 GO:0008203 cholesterol metabolic process(GO:0008203)
0.1 2.2 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.1 0.6 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 2.6 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 1.7 GO:0061053 somite development(GO:0061053)
0.1 1.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 2.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 4.1 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.4 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.9 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 2.1 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.2 GO:0048290 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.7 GO:0030888 regulation of B cell proliferation(GO:0030888)
0.0 1.0 GO:0035904 aorta development(GO:0035904)
0.0 1.1 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 1.0 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 1.6 GO:0050808 synapse organization(GO:0050808)
0.0 1.6 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.0 0.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.7 GO:0021761 limbic system development(GO:0021761)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 2.5 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 3.8 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.4 GO:0030815 negative regulation of cAMP metabolic process(GO:0030815)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 1.5 GO:0042107 cytokine metabolic process(GO:0042107)
0.0 1.1 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.9 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.8 GO:0061337 cardiac conduction(GO:0061337)
0.0 1.5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.6 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.5 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 0.3 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.5 GO:0044609 DBIRD complex(GO:0044609)
2.8 11.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
2.7 8.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
2.5 34.6 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.9 7.4 GO:0031417 NatC complex(GO:0031417)
1.8 7.3 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
1.7 14.0 GO:0005587 collagen type IV trimer(GO:0005587)
1.6 4.9 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
1.6 4.8 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
1.4 4.3 GO:0070195 growth hormone receptor complex(GO:0070195)
1.4 17.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.4 8.5 GO:0097443 sorting endosome(GO:0097443)
1.4 4.2 GO:0097453 mesaxon(GO:0097453) ensheathing process(GO:1990015)
1.3 1.3 GO:0005641 nuclear envelope lumen(GO:0005641)
1.3 17.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
1.3 10.1 GO:0005593 FACIT collagen trimer(GO:0005593)
1.2 4.6 GO:0031673 H zone(GO:0031673)
1.1 4.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
1.1 20.5 GO:0031089 platelet dense granule lumen(GO:0031089)
1.1 11.0 GO:0097427 microtubule bundle(GO:0097427)
1.1 8.6 GO:0035976 AP1 complex(GO:0035976)
1.0 11.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
1.0 2.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
1.0 6.0 GO:1990769 proximal neuron projection(GO:1990769)
0.9 6.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.9 5.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.9 12.8 GO:0005883 neurofilament(GO:0005883)
0.8 16.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.8 3.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.8 2.4 GO:0034685 integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.8 8.0 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.7 5.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.7 4.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.7 9.7 GO:0031209 SCAR complex(GO:0031209)
0.6 8.3 GO:0005577 fibrinogen complex(GO:0005577)
0.6 2.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.6 3.8 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.6 3.1 GO:0070847 core mediator complex(GO:0070847)
0.6 7.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.6 14.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.6 2.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.6 25.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.6 2.2 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.5 2.2 GO:0035838 growing cell tip(GO:0035838)
0.5 2.1 GO:0070695 FHF complex(GO:0070695)
0.5 3.7 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.5 3.6 GO:0044294 dendritic growth cone(GO:0044294)
0.5 4.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.5 2.9 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.5 2.4 GO:0097422 tubular endosome(GO:0097422)
0.5 5.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.5 46.4 GO:0005901 caveola(GO:0005901)
0.5 6.9 GO:0005916 fascia adherens(GO:0005916)
0.5 1.8 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.5 2.7 GO:0070852 cell body fiber(GO:0070852)
0.4 6.2 GO:0042599 lamellar body(GO:0042599)
0.4 2.2 GO:0071546 pi-body(GO:0071546)
0.4 4.3 GO:0042587 glycogen granule(GO:0042587)
0.4 1.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.4 3.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.4 38.0 GO:0043195 terminal bouton(GO:0043195)
0.4 2.0 GO:0033647 host cell cytoplasm(GO:0030430) host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) host cell cytoplasm part(GO:0033655) tubulin complex(GO:0045298)
0.4 20.7 GO:0005581 collagen trimer(GO:0005581)
0.4 6.5 GO:0005922 connexon complex(GO:0005922)
0.4 1.9 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.4 2.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.3 5.5 GO:0030056 hemidesmosome(GO:0030056)
0.3 3.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 6.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 2.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 6.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 1.6 GO:0030897 HOPS complex(GO:0030897)
0.3 9.1 GO:0042629 mast cell granule(GO:0042629)
0.3 1.5 GO:0005927 muscle tendon junction(GO:0005927)
0.3 1.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 10.6 GO:0043679 axon terminus(GO:0043679)
0.3 0.3 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.3 4.5 GO:0030914 STAGA complex(GO:0030914)
0.3 8.6 GO:0032420 stereocilium(GO:0032420)
0.3 9.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.3 24.9 GO:0016459 myosin complex(GO:0016459)
0.3 6.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.3 2.4 GO:0034464 BBSome(GO:0034464)
0.3 34.9 GO:0043204 perikaryon(GO:0043204)
0.3 22.0 GO:0042734 presynaptic membrane(GO:0042734)
0.3 1.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 1.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 1.8 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 3.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 3.3 GO:0030478 actin cap(GO:0030478)
0.2 8.4 GO:0097542 ciliary tip(GO:0097542)
0.2 3.0 GO:0036038 MKS complex(GO:0036038)
0.2 8.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 1.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 17.9 GO:0005604 basement membrane(GO:0005604)
0.2 6.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2 11.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 4.9 GO:0071565 nBAF complex(GO:0071565)
0.2 4.3 GO:0042627 chylomicron(GO:0042627)
0.2 4.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 1.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 10.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 0.3 GO:0032009 early phagosome(GO:0032009)
0.2 2.5 GO:0044853 plasma membrane raft(GO:0044853)
0.2 1.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 7.2 GO:0043198 dendritic shaft(GO:0043198)
0.2 10.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 2.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 20.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 10.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 3.0 GO:0005871 kinesin complex(GO:0005871)
0.1 36.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 3.6 GO:0030057 desmosome(GO:0030057)
0.1 9.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 11.7 GO:0005776 autophagosome(GO:0005776)
0.1 7.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 6.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.1 GO:0035869 ciliary transition zone(GO:0035869)
0.1 2.7 GO:0060170 ciliary membrane(GO:0060170)
0.1 10.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 3.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.2 GO:0005844 polysome(GO:0005844)
0.1 8.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 2.3 GO:0016580 Sin3 complex(GO:0016580)
0.1 3.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 2.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 2.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.9 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.5 GO:0014704 intercalated disc(GO:0014704)
0.1 2.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 4.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 1.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 4.1 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.6 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 1.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 14.5 GO:0019898 extrinsic component of membrane(GO:0019898)
0.1 4.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.5 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 2.4 GO:0005903 brush border(GO:0005903)
0.1 2.1 GO:0001772 immunological synapse(GO:0001772)
0.1 1.7 GO:0031672 A band(GO:0031672)
0.1 19.0 GO:0044297 cell body(GO:0044297)
0.1 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 12.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 2.8 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.1 GO:0005902 microvillus(GO:0005902)
0.0 61.9 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 52.8 GO:0005615 extracellular space(GO:0005615)
0.0 0.8 GO:0043235 receptor complex(GO:0043235)
0.0 2.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 3.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.4 GO:0034702 ion channel complex(GO:0034702)
0.0 0.6 GO:0031904 endosome lumen(GO:0031904)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.1 GO:0005770 late endosome(GO:0005770)
0.0 4.8 GO:0005769 early endosome(GO:0005769)
0.0 0.7 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.8 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.9 GO:0098793 presynapse(GO:0098793)
0.0 0.2 GO:0035097 histone methyltransferase complex(GO:0035097)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 19.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
5.7 39.9 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
5.2 26.0 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
3.5 14.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
3.1 9.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
3.1 9.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
2.9 8.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
2.3 2.3 GO:0070699 type II activin receptor binding(GO:0070699)
2.1 34.1 GO:0097109 neuroligin family protein binding(GO:0097109)
2.1 18.9 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
2.1 26.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
2.1 6.2 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.9 7.7 GO:0019770 IgG receptor activity(GO:0019770)
1.8 5.5 GO:0017129 triglyceride binding(GO:0017129)
1.8 9.0 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
1.8 5.4 GO:0061663 NEDD8 ligase activity(GO:0061663)
1.7 5.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.7 5.0 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
1.7 13.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
1.6 19.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.6 4.7 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
1.5 19.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
1.4 4.3 GO:0005148 prolactin receptor binding(GO:0005148)
1.4 8.5 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
1.4 4.2 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
1.3 4.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
1.3 6.7 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
1.3 3.8 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
1.3 15.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.2 8.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.2 3.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
1.2 12.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.1 3.4 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
1.1 6.8 GO:0005134 interleukin-2 receptor binding(GO:0005134)
1.1 9.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.1 8.9 GO:0034711 inhibin binding(GO:0034711)
1.1 3.3 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
1.1 3.3 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
1.1 2.2 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
1.1 18.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.1 3.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
1.1 14.0 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
1.1 11.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
1.0 4.2 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
1.0 16.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.0 3.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.0 13.3 GO:0042608 T cell receptor binding(GO:0042608)
1.0 4.9 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.0 7.7 GO:0001849 complement component C1q binding(GO:0001849)
1.0 4.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.9 2.8 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.9 4.7 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.9 9.3 GO:0003696 satellite DNA binding(GO:0003696)
0.9 7.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.9 2.7 GO:0035671 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.9 0.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.9 2.6 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.8 8.5 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.8 8.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.8 10.7 GO:0070700 BMP receptor binding(GO:0070700)
0.8 3.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.8 2.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.8 17.5 GO:0071837 HMG box domain binding(GO:0071837)
0.8 72.9 GO:0005518 collagen binding(GO:0005518)
0.8 6.9 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.8 3.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.8 3.8 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.7 2.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.7 6.4 GO:0048495 Roundabout binding(GO:0048495)
0.7 2.8 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.7 4.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.7 9.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.7 15.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.7 7.5 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.7 6.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.7 3.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.7 4.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.7 8.7 GO:0031005 filamin binding(GO:0031005)
0.7 2.0 GO:0086076 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.7 6.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.7 9.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.7 3.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.6 5.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.6 0.6 GO:0032089 NACHT domain binding(GO:0032089)
0.6 2.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.6 3.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.6 8.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.6 1.9 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.6 3.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.6 2.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.6 1.8 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.6 3.0 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.6 7.7 GO:0038132 neuregulin binding(GO:0038132)
0.6 3.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.6 1.7 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.6 1.7 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.5 16.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.5 4.8 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.5 2.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.5 3.7 GO:0097643 amylin receptor activity(GO:0097643)
0.5 2.6 GO:0071253 connexin binding(GO:0071253)
0.5 5.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.5 2.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.5 11.7 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.5 3.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.5 21.7 GO:0003785 actin monomer binding(GO:0003785)
0.5 3.4 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.5 7.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.5 1.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 6.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.5 1.4 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.5 4.2 GO:0033691 sialic acid binding(GO:0033691)
0.5 11.8 GO:0031489 myosin V binding(GO:0031489)
0.5 1.8 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.5 3.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.4 3.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.4 13.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.4 10.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.4 1.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.4 1.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.4 5.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.4 15.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.4 9.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.4 1.5 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.4 3.8 GO:0045545 syndecan binding(GO:0045545)
0.4 15.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.4 2.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.4 3.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.3 2.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 2.4 GO:0034452 dynactin binding(GO:0034452)
0.3 2.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.3 2.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.3 15.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 27.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.3 2.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 1.7 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 1.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 1.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.3 3.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.3 5.3 GO:0048185 activin binding(GO:0048185)
0.3 8.9 GO:0070840 dynein complex binding(GO:0070840)
0.3 3.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.3 8.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.3 14.0 GO:0030507 spectrin binding(GO:0030507)
0.3 5.9 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.3 4.3 GO:0050700 CARD domain binding(GO:0050700)
0.3 4.6 GO:0035064 methylated histone binding(GO:0035064)
0.3 4.3 GO:0019864 IgG binding(GO:0019864)
0.3 7.5 GO:0001848 complement binding(GO:0001848)
0.3 3.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 2.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 6.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.3 6.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 3.1 GO:0005243 gap junction channel activity(GO:0005243)
0.3 2.0 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3 4.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.3 4.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 3.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 1.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.3 1.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.3 1.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.3 2.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 2.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.3 0.5 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.3 6.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 12.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.2 4.4 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.2 25.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.2 GO:0034056 estrogen response element binding(GO:0034056)
0.2 4.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 2.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 0.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.2 6.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 2.3 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.2 3.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 2.9 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2 2.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 8.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 4.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 0.9 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 4.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 10.3 GO:0008009 chemokine activity(GO:0008009)
0.2 1.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 1.5 GO:0042605 peptide antigen binding(GO:0042605)
0.2 3.7 GO:0035497 cAMP response element binding(GO:0035497)
0.2 3.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 3.8 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.2 2.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 5.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.2 0.8 GO:0032810 sterol response element binding(GO:0032810)
0.2 1.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.2 2.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.9 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.2 1.9 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 2.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 6.1 GO:0002039 p53 binding(GO:0002039)
0.2 4.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 11.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 10.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.2 7.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 1.8 GO:0031419 cobalamin binding(GO:0031419)
0.2 0.5 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.2 2.9 GO:0005112 Notch binding(GO:0005112)
0.2 0.5 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 1.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 1.7 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.8 GO:0035198 miRNA binding(GO:0035198)
0.2 1.5 GO:0015232 heme transporter activity(GO:0015232)
0.2 2.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 2.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 2.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 1.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 2.4 GO:0030276 clathrin binding(GO:0030276)
0.1 1.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.6 GO:0031386 protein tag(GO:0031386)
0.1 1.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.5 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.7 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 10.9 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 2.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 1.1 GO:0004969 histamine receptor activity(GO:0004969)
0.1 4.4 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 1.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 3.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.2 GO:0008432 JUN kinase binding(GO:0008432)
0.1 9.3 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.5 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 30.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 47.7 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 1.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.9 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 2.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 2.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 5.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 1.1 GO:0005537 mannose binding(GO:0005537)
0.1 0.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 5.8 GO:0005262 calcium channel activity(GO:0005262)
0.1 2.7 GO:0015248 sterol transporter activity(GO:0015248)
0.1 4.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 1.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 9.9 GO:0005179 hormone activity(GO:0005179)
0.1 0.4 GO:0005497 androgen binding(GO:0005497)
0.1 27.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 1.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.9 GO:0016502 purinergic nucleotide receptor activity(GO:0001614) extracellular ATP-gated cation channel activity(GO:0004931) nucleotide receptor activity(GO:0016502) ATP-gated ion channel activity(GO:0035381)
0.1 4.1 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 4.9 GO:0019905 syntaxin binding(GO:0019905)
0.1 0.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 3.6 GO:0017069 snRNA binding(GO:0017069)
0.1 10.8 GO:0005506 iron ion binding(GO:0005506)
0.1 3.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.4 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 4.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.5 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 5.4 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.1 8.5 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.7 GO:0070888 E-box binding(GO:0070888)
0.1 1.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 1.0 GO:0005521 lamin binding(GO:0005521)
0.0 6.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 1.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.8 GO:0071617 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 4.4 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.2 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.3 GO:0002020 protease binding(GO:0002020)
0.0 1.4 GO:0046906 heme binding(GO:0020037) tetrapyrrole binding(GO:0046906)
0.0 0.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.0 2.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.7 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 3.0 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.3 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 69.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.8 27.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.7 13.6 PID ALK2 PATHWAY ALK2 signaling events
0.6 33.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.6 26.3 NABA COLLAGENS Genes encoding collagen proteins
0.6 1.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.5 9.4 PID S1P S1P3 PATHWAY S1P3 pathway
0.5 12.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.5 13.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.5 7.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.4 3.1 PID IL3 PATHWAY IL3-mediated signaling events
0.4 14.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.3 3.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.3 26.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.3 2.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.3 14.0 PID IFNG PATHWAY IFN-gamma pathway
0.3 5.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.3 4.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 8.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 6.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.2 9.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 11.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 8.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 2.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 1.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 6.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 10.0 PID BMP PATHWAY BMP receptor signaling
0.2 9.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.2 52.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 3.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 4.5 PID CONE PATHWAY Visual signal transduction: Cones
0.2 35.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 6.2 ST GA13 PATHWAY G alpha 13 Pathway
0.2 8.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 5.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 6.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 3.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 9.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 2.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 5.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 0.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 25.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 3.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 5.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 4.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.1 PID FGF PATHWAY FGF signaling pathway
0.1 3.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.1 PID IL1 PATHWAY IL1-mediated signaling events
0.1 4.2 PID AP1 PATHWAY AP-1 transcription factor network
0.1 30.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 2.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 1.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.0 NABA MATRISOME Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.1 0.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 1.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 0.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 1.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.6 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 2.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
1.7 46.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
1.4 36.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.3 17.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.2 4.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
1.1 16.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
1.1 1.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
1.1 69.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.9 26.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.8 1.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.6 7.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.6 24.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.6 11.2 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.6 6.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.5 11.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.5 5.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.5 7.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.5 10.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.5 14.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.5 3.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.5 7.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.5 8.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.5 24.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.4 7.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.4 18.1 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.4 1.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.4 5.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.4 6.6 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.4 2.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.4 6.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.4 5.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 7.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.3 16.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3 6.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 11.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.3 1.6 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.3 9.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 0.9 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.3 6.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.3 7.1 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.3 1.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.3 13.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3 11.3 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.3 9.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3 8.3 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.3 11.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.3 3.9 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.3 1.8 REACTOME INSULIN RECEPTOR SIGNALLING CASCADE Genes involved in Insulin receptor signalling cascade
0.3 1.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 9.7 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.2 3.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 1.9 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.2 9.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 8.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 3.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.2 6.8 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 5.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 3.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 8.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.2 2.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 3.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 1.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 4.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 4.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 11.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 6.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 10.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 5.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 10.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 6.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 22.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 5.4 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.1 2.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 9.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 3.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 0.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 2.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.8 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 1.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.3 REACTOME KINESINS Genes involved in Kinesins
0.1 2.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.5 REACTOME GABA RECEPTOR ACTIVATION Genes involved in GABA receptor activation
0.1 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.6 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1 2.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.8 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 5.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.0 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.1 1.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 5.2 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 7.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 2.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME GPCR LIGAND BINDING Genes involved in GPCR ligand binding
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements