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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for ZNF333

Z-value: 0.53

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Transcription factors associated with ZNF333

Gene Symbol Gene ID Gene Info
ZNF333
ENSG00000160961.7 zinc finger protein 333

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF333hg19_v2_chr19_+_14800711_148009170.082.2e-01Click!

Activity profile of ZNF333 motif

Sorted Z-values of ZNF333 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_92085262 14.29 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr18_+_71815743 10.85 ENST00000169551.6
ENST00000580087.1
TIMM21
translocase of inner mitochondrial membrane 21 homolog (yeast)
chr6_-_32908765 6.95 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr11_-_85376121 5.47 ENST00000527447.1
CREBZF
CREB/ATF bZIP transcription factor
chr2_-_127977654 5.30 ENST00000409327.1
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr12_-_71031220 5.25 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr6_-_52705641 4.65 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chrX_-_21776281 4.55 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr7_-_115670792 4.43 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr14_-_90798418 4.34 ENST00000354366.3
NRDE2
NRDE-2, necessary for RNA interference, domain containing
chr7_-_115670804 4.02 ENST00000320239.7
TFEC
transcription factor EC
chr5_+_137225158 4.01 ENST00000290431.5
PKD2L2
polycystic kidney disease 2-like 2
chr6_+_131894284 3.92 ENST00000368087.3
ENST00000356962.2
ARG1
arginase 1
chr1_+_19638788 3.85 ENST00000375155.3
ENST00000375153.3
ENST00000400548.2
PQLC2
PQ loop repeat containing 2
chr12_-_71031185 3.80 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr19_-_45004556 3.79 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
ZNF180
zinc finger protein 180
chr9_-_21351377 3.61 ENST00000380210.1
IFNA6
interferon, alpha 6
chr14_+_76618242 3.39 ENST00000557542.1
ENST00000557263.1
ENST00000557207.1
ENST00000312858.5
ENST00000261530.7
GPATCH2L
G patch domain containing 2-like
chr16_+_84328252 3.36 ENST00000219454.5
WFDC1
WAP four-disulfide core domain 1
chr11_-_6440624 3.34 ENST00000311051.3
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr5_+_140800638 3.11 ENST00000398587.2
ENST00000518882.1
PCDHGA11
protocadherin gamma subfamily A, 11
chr1_+_36789335 3.09 ENST00000373137.2
RP11-268J15.5
RP11-268J15.5
chr16_+_84328429 3.00 ENST00000568638.1
WFDC1
WAP four-disulfide core domain 1
chr12_+_112563303 2.92 ENST00000412615.2
TRAFD1
TRAF-type zinc finger domain containing 1
chr11_-_117698765 2.88 ENST00000532119.1
FXYD2
FXYD domain containing ion transport regulator 2
chr8_+_18248755 2.72 ENST00000286479.3
NAT2
N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr5_+_137225125 2.66 ENST00000350250.4
ENST00000508638.1
ENST00000502810.1
ENST00000508883.1
PKD2L2
polycystic kidney disease 2-like 2
chr20_+_58515417 2.47 ENST00000360816.3
FAM217B
family with sequence similarity 217, member B
chr12_+_112563335 2.37 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr6_+_160327974 2.37 ENST00000252660.4
MAS1
MAS1 oncogene
chrX_+_11311533 2.35 ENST00000380714.3
ENST00000380712.3
ENST00000348912.4
AMELX
amelogenin, X-linked
chr3_+_38323785 2.23 ENST00000466887.1
ENST00000448498.1
SLC22A14
solute carrier family 22, member 14
chr20_-_44600810 2.18 ENST00000322927.2
ENST00000426788.1
ZNF335
zinc finger protein 335
chr5_+_140535577 2.16 ENST00000539533.1
PCDHB17
Protocadherin-psi1; Uncharacterized protein
chr17_-_3337135 2.11 ENST00000248384.1
OR1E2
olfactory receptor, family 1, subfamily E, member 2
chr14_+_85996507 2.09 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr9_-_19786926 2.09 ENST00000341998.2
ENST00000286344.3
SLC24A2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr3_+_35721106 2.08 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr16_-_20702578 2.06 ENST00000307493.4
ENST00000219151.4
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr6_+_50786414 2.04 ENST00000344788.3
ENST00000393655.3
ENST00000263046.4
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr14_+_85996471 2.00 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chrX_-_107975917 1.97 ENST00000563887.1
RP6-24A23.6
Uncharacterized protein
chr2_+_79412357 1.95 ENST00000466387.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chr2_-_228497888 1.94 ENST00000264387.4
ENST00000409066.1
C2orf83
chromosome 2 open reading frame 83
chr12_-_7848364 1.90 ENST00000329913.3
GDF3
growth differentiation factor 3
chr14_+_23842018 1.88 ENST00000397242.2
ENST00000329715.2
IL25
interleukin 25
chr11_+_18433840 1.86 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr5_+_140207536 1.74 ENST00000529310.1
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr2_-_178753465 1.71 ENST00000389683.3
PDE11A
phosphodiesterase 11A
chr1_+_225600404 1.66 ENST00000366845.2
AC092811.1
AC092811.1
chr5_-_27038683 1.66 ENST00000511822.1
ENST00000231021.4
CDH9
cadherin 9, type 2 (T1-cadherin)
chr3_+_53528659 1.65 ENST00000350061.5
CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr6_-_135375986 1.58 ENST00000525067.1
ENST00000367822.5
ENST00000367837.5
HBS1L
HBS1-like (S. cerevisiae)
chr17_-_2966901 1.57 ENST00000575751.1
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr3_-_113918254 1.54 ENST00000460779.1
DRD3
dopamine receptor D3
chrX_-_30595959 1.54 ENST00000378962.3
CXorf21
chromosome X open reading frame 21
chr6_-_46620522 1.47 ENST00000275016.2
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr5_+_137203465 1.46 ENST00000239926.4
MYOT
myotilin
chrX_-_49121165 1.46 ENST00000376207.4
ENST00000376199.2
FOXP3
forkhead box P3
chr7_-_27169801 1.45 ENST00000511914.1
HOXA4
homeobox A4
chr11_-_117698787 1.39 ENST00000260287.2
FXYD2
FXYD domain containing ion transport regulator 2
chr17_-_46690839 1.36 ENST00000498634.2
HOXB8
homeobox B8
chr2_+_233527443 1.32 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr6_+_166945369 1.30 ENST00000598601.1
Z98049.1
CDNA FLJ25492 fis, clone CBR01389; Uncharacterized protein
chrX_+_122318318 1.25 ENST00000371251.1
ENST00000371256.5
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr7_-_36406750 1.21 ENST00000453212.1
ENST00000415803.2
ENST00000440378.1
ENST00000431396.1
ENST00000317020.6
ENST00000436884.1
KIAA0895
KIAA0895
chrY_-_6742068 1.19 ENST00000215479.5
AMELY
amelogenin, Y-linked
chr11_+_33061543 1.19 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr2_-_128432639 1.18 ENST00000545738.2
ENST00000355119.4
ENST00000409808.2
LIMS2
LIM and senescent cell antigen-like domains 2
chr3_-_126327398 1.14 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr5_-_35195338 1.11 ENST00000509839.1
PRLR
prolactin receptor
chr7_-_83824169 1.08 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chrX_+_99839799 1.07 ENST00000373031.4
TNMD
tenomodulin
chr1_-_169599314 0.98 ENST00000367786.2
ENST00000458599.2
ENST00000367795.2
ENST00000263686.6
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr4_+_71108300 0.94 ENST00000304954.3
CSN3
casein kappa
chr1_+_55013889 0.91 ENST00000343744.2
ENST00000371316.3
ACOT11
acyl-CoA thioesterase 11
chr16_+_87636474 0.89 ENST00000284262.2
JPH3
junctophilin 3
chr8_-_11725549 0.85 ENST00000505496.2
ENST00000534636.1
ENST00000524500.1
ENST00000345125.3
ENST00000453527.2
ENST00000527215.2
ENST00000532392.1
ENST00000533455.1
ENST00000534510.1
ENST00000530640.2
ENST00000531089.1
ENST00000532656.2
ENST00000531502.1
ENST00000434271.1
ENST00000353047.6
CTSB
cathepsin B
chr12_-_49393092 0.83 ENST00000421952.2
DDN
dendrin
chr17_-_41623716 0.82 ENST00000319349.5
ETV4
ets variant 4
chr4_+_106473768 0.79 ENST00000265154.2
ENST00000420470.2
ARHGEF38
Rho guanine nucleotide exchange factor (GEF) 38
chr12_-_10251539 0.74 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr11_+_12766583 0.71 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr14_+_22748980 0.66 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr12_+_60058458 0.61 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr2_+_185463093 0.60 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr1_-_169599353 0.60 ENST00000367793.2
ENST00000367794.2
ENST00000367792.2
ENST00000367791.2
ENST00000367788.2
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr11_-_66313699 0.60 ENST00000526986.1
ENST00000310442.3
ZDHHC24
zinc finger, DHHC-type containing 24
chr18_+_46065393 0.58 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr14_+_24099318 0.58 ENST00000432832.2
DHRS2
dehydrogenase/reductase (SDR family) member 2
chr10_+_118350468 0.57 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr11_-_18062872 0.52 ENST00000250018.2
TPH1
tryptophan hydroxylase 1
chr20_+_56964169 0.51 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr5_-_78281603 0.50 ENST00000264914.4
ARSB
arylsulfatase B
chr10_+_118350522 0.47 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1
pancreatic lipase-related protein 1
chrX_-_114253536 0.47 ENST00000371936.1
IL13RA2
interleukin 13 receptor, alpha 2
chr12_-_7656357 0.45 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
CD163
CD163 molecule
chr4_-_186696425 0.40 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr4_+_110749143 0.40 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr6_+_17110726 0.39 ENST00000354384.5
STMND1
stathmin domain containing 1
chr4_-_100356551 0.32 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr12_+_58176525 0.31 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr1_+_159409512 0.25 ENST00000423932.3
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr5_-_147162078 0.23 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr17_-_33446735 0.21 ENST00000460118.2
ENST00000335858.7
RAD51D
RAD51 paralog D
chr13_-_103719196 0.19 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr4_-_26492076 0.18 ENST00000295589.3
CCKAR
cholecystokinin A receptor
chr1_-_51763661 0.12 ENST00000530004.1
TTC39A
tetratricopeptide repeat domain 39A
chr8_+_40010989 0.07 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr12_-_10959892 0.04 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chr7_-_25268104 0.03 ENST00000222674.2
NPVF
neuropeptide VF precursor

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF333

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
1.3 3.9 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
1.3 3.8 GO:1903401 L-lysine transmembrane transport(GO:1903401)
1.1 3.3 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.8 10.9 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.7 1.5 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.7 2.1 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.7 4.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.6 1.9 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.5 1.9 GO:0048859 formation of anatomical boundary(GO:0048859)
0.4 2.3 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.4 1.5 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883)
0.3 5.3 GO:0042574 retinal metabolic process(GO:0042574)
0.3 1.9 GO:0009624 response to nematode(GO:0009624)
0.3 1.9 GO:0019249 lactate biosynthetic process(GO:0019249)
0.3 2.0 GO:0072501 cellular divalent inorganic anion homeostasis(GO:0072501)
0.3 1.6 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 1.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.3 4.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 1.1 GO:0048880 sensory system development(GO:0048880)
0.2 3.6 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 4.3 GO:0016246 RNA interference(GO:0016246)
0.2 1.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 0.5 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.2 6.7 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 1.9 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 2.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 1.5 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 1.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 20.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 1.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 2.2 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.1 0.5 GO:0051597 response to methylmercury(GO:0051597)
0.1 3.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 4.2 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 0.6 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 2.7 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 2.2 GO:0015695 organic cation transport(GO:0015695)
0.1 1.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 8.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.2 GO:0034505 tooth mineralization(GO:0034505)
0.1 0.5 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.1 6.4 GO:0061045 negative regulation of wound healing(GO:0061045)
0.1 2.1 GO:0060292 long term synaptic depression(GO:0060292)
0.1 0.2 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 10.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 5.5 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 4.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.9 GO:0046697 decidualization(GO:0046697)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.9 GO:0035640 exploration behavior(GO:0035640)
0.0 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 1.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.7 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.9 GO:0009409 response to cold(GO:0009409)
0.0 0.9 GO:0007595 lactation(GO:0007595)
0.0 0.4 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 2.7 GO:0006941 striated muscle contraction(GO:0006941)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 10.9 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.8 4.5 GO:0005927 muscle tendon junction(GO:0005927)
0.4 3.3 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.3 5.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.9 GO:0030314 junctional membrane complex(GO:0030314)
0.2 4.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.7 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 1.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.9 GO:0036021 endolysosome lumen(GO:0036021)
0.1 1.6 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 9.0 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 3.9 GO:0035580 specific granule lumen(GO:0035580)
0.0 4.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 1.1 GO:0031904 endosome lumen(GO:0031904)
0.0 7.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 3.8 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 1.9 GO:0031514 motile cilium(GO:0031514)
0.0 1.7 GO:0043204 perikaryon(GO:0043204)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0005502 11-cis retinal binding(GO:0005502)
1.3 3.8 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.8 2.3 GO:0046848 hydroxyapatite binding(GO:0046848)
0.7 2.7 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.6 1.9 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.5 1.6 GO:0042806 fucose binding(GO:0042806)
0.5 2.4 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.4 2.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 5.2 GO:0045499 chemorepellent activity(GO:0045499)
0.3 8.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 1.7 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.3 3.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 4.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 1.9 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.3 3.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 1.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2 2.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.2 1.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 1.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 5.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 3.3 GO:0048156 tau protein binding(GO:0048156)
0.2 0.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 1.6 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 1.5 GO:0051525 NFAT protein binding(GO:0051525)
0.1 2.2 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.1 0.6 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 1.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 4.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.3 GO:0035276 aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.1 3.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.5 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 7.6 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.2 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 6.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 2.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.7 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 1.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 8.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.9 GO:0043394 proteoglycan binding(GO:0043394)
0.0 2.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 17.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.9 GO:0005125 cytokine activity(GO:0005125)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID CONE PATHWAY Visual signal transduction: Cones
0.1 6.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 1.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 8.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 3.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 3.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 3.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 4.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 4.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 5.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 1.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 2.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 2.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.6 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts