Project
GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for ZNF384
Z-value: 1.18
Motif logo
Transcription factors associated with ZNF384
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF384 | hg19_v2_chr12_-_6798616_6798684 | -0.51 | 4.8e-16 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF384
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 166.4 | GO:0090114 | COPII-coated vesicle budding(GO:0090114) |
| 3.4 | 157.2 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 5.0 | 155.6 | GO:0061641 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 2.1 | 147.8 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 1.5 | 144.1 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 1.4 | 115.2 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 2.3 | 112.9 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 2.8 | 110.3 | GO:2000816 | negative regulation of mitotic sister chromatid separation(GO:2000816) |
| 10.9 | 108.6 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 25.5 | 102.0 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.8 | 222.7 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.8 | 132.9 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.5 | 123.0 | GO:0031965 | nuclear membrane(GO:0031965) |
| 2.2 | 120.6 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 1.6 | 115.0 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 1.0 | 109.5 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 2.5 | 101.0 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.9 | 100.1 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
| 1.5 | 98.9 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 5.0 | 84.9 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 224.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.2 | 156.8 | GO:0003723 | RNA binding(GO:0003723) |
| 1.2 | 134.8 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 3.8 | 124.1 | GO:0070717 | poly-purine tract binding(GO:0070717) |
| 0.4 | 122.8 | GO:0045296 | cadherin binding(GO:0045296) |
| 2.5 | 116.0 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 10.6 | 106.1 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 13.9 | 97.1 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 1.7 | 74.5 | GO:0003785 | actin monomer binding(GO:0003785) |
| 3.2 | 74.0 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.3 | 217.0 | PID AURORA B PATHWAY | Aurora B signaling |
| 7.3 | 101.8 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 1.3 | 100.1 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 1.9 | 92.2 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.8 | 74.6 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 1.0 | 71.6 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.9 | 60.1 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 1.6 | 58.5 | PID MYC PATHWAY | C-MYC pathway |
| 0.7 | 57.5 | PID E2F PATHWAY | E2F transcription factor network |
| 2.2 | 54.0 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.1 | 297.8 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 7.9 | 205.1 | REACTOME KINESINS | Genes involved in Kinesins |
| 2.1 | 200.8 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 2.5 | 139.0 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 1.1 | 139.0 | REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | Genes involved in Processing of Capped Intron-Containing Pre-mRNA |
| 0.8 | 134.5 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 4.4 | 117.7 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 1.7 | 104.2 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 2.9 | 103.5 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.5 | 88.7 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |