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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for ZNF740_ZNF219
Z-value: 0.68
Motif logo
Transcription factors associated with ZNF740_ZNF219
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ZNF740
|
ENSG00000139651.9 | zinc finger protein 740 |
|
ZNF219
|
ENSG00000165804.11 | zinc finger protein 219 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF219 | hg19_v2_chr14_-_21566731_21566836, hg19_v2_chr14_-_21567009_21567173 | -0.28 | 3.2e-05 | Click! |
Activity profile of ZNF740_ZNF219 motif
Sorted Z-values of ZNF740_ZNF219 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_43148625 | 43.77 |
ENST00000436427.1
|
YBX1
|
Y box binding protein 1 |
| chr11_-_46142948 | 34.28 |
ENST00000257821.4
|
PHF21A
|
PHD finger protein 21A |
| chr1_-_150208363 | 31.89 |
ENST00000436748.2
|
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr1_-_150208498 | 31.43 |
ENST00000314136.8
|
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr1_-_150208412 | 31.21 |
ENST00000532744.1
ENST00000369114.5 ENST00000369115.2 ENST00000369116.4 |
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr11_-_46142615 | 30.29 |
ENST00000529734.1
ENST00000323180.6 |
PHF21A
|
PHD finger protein 21A |
| chr18_+_3449821 | 30.20 |
ENST00000407501.2
ENST00000405385.3 ENST00000546979.1 |
TGIF1
|
TGFB-induced factor homeobox 1 |
| chr18_+_3449695 | 27.50 |
ENST00000343820.5
|
TGIF1
|
TGFB-induced factor homeobox 1 |
| chr6_-_32157947 | 24.72 |
ENST00000375050.4
|
PBX2
|
pre-B-cell leukemia homeobox 2 |
| chr1_-_150208291 | 24.54 |
ENST00000533654.1
|
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr2_-_61765315 | 24.09 |
ENST00000406957.1
ENST00000401558.2 |
XPO1
|
exportin 1 (CRM1 homolog, yeast) |
| chr10_-_13390021 | 23.46 |
ENST00000537130.1
|
SEPHS1
|
selenophosphate synthetase 1 |
| chr8_-_101734170 | 22.06 |
ENST00000522387.1
ENST00000518196.1 |
PABPC1
|
poly(A) binding protein, cytoplasmic 1 |
| chr17_+_36861735 | 21.18 |
ENST00000378137.5
ENST00000325718.7 |
MLLT6
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 |
| chr20_-_52210368 | 21.15 |
ENST00000371471.2
|
ZNF217
|
zinc finger protein 217 |
| chr2_-_148779106 | 20.39 |
ENST00000416719.1
ENST00000264169.2 |
ORC4
|
origin recognition complex, subunit 4 |
| chr2_-_174828892 | 20.34 |
ENST00000418194.2
|
SP3
|
Sp3 transcription factor |
| chr8_+_95653373 | 19.57 |
ENST00000358397.5
|
ESRP1
|
epithelial splicing regulatory protein 1 |
| chr1_+_43148059 | 19.36 |
ENST00000321358.7
ENST00000332220.6 |
YBX1
|
Y box binding protein 1 |
| chr5_+_137688285 | 19.29 |
ENST00000314358.5
|
KDM3B
|
lysine (K)-specific demethylase 3B |
| chr7_+_26241325 | 19.00 |
ENST00000456948.1
ENST00000409747.1 |
CBX3
|
chromobox homolog 3 |
| chr7_+_26241310 | 18.81 |
ENST00000396386.2
|
CBX3
|
chromobox homolog 3 |
| chr1_-_150208320 | 18.46 |
ENST00000534220.1
|
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr8_+_95653302 | 18.13 |
ENST00000423620.2
ENST00000433389.2 |
ESRP1
|
epithelial splicing regulatory protein 1 |
| chr8_+_95653427 | 17.34 |
ENST00000454170.2
|
ESRP1
|
epithelial splicing regulatory protein 1 |
| chr2_-_161349909 | 16.14 |
ENST00000392753.3
|
RBMS1
|
RNA binding motif, single stranded interacting protein 1 |
| chr2_-_230786619 | 15.70 |
ENST00000389045.3
ENST00000409677.1 |
TRIP12
|
thyroid hormone receptor interactor 12 |
| chr14_-_24615805 | 15.51 |
ENST00000560410.1
|
PSME2
|
proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
| chr2_-_64881018 | 15.49 |
ENST00000313349.3
|
SERTAD2
|
SERTA domain containing 2 |
| chr1_-_167906277 | 15.39 |
ENST00000271373.4
|
MPC2
|
mitochondrial pyruvate carrier 2 |
| chr14_-_23451467 | 15.34 |
ENST00000555074.1
ENST00000361265.4 |
RP11-298I3.5
AJUBA
|
RP11-298I3.5 ajuba LIM protein |
| chr2_-_61697862 | 14.69 |
ENST00000398571.2
|
USP34
|
ubiquitin specific peptidase 34 |
| chr12_-_57522813 | 14.48 |
ENST00000556155.1
|
STAT6
|
signal transducer and activator of transcription 6, interleukin-4 induced |
| chr1_+_27022839 | 14.24 |
ENST00000457599.2
|
ARID1A
|
AT rich interactive domain 1A (SWI-like) |
| chr9_+_100745615 | 13.93 |
ENST00000339399.4
|
ANP32B
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B |
| chr1_-_67896009 | 13.71 |
ENST00000370990.5
|
SERBP1
|
SERPINE1 mRNA binding protein 1 |
| chr18_+_657578 | 13.66 |
ENST00000323274.10
|
TYMS
|
thymidylate synthetase |
| chr12_+_69004619 | 13.47 |
ENST00000250559.9
ENST00000393436.5 ENST00000425247.2 ENST00000489473.2 ENST00000422358.2 ENST00000541167.1 ENST00000538283.1 ENST00000341355.5 ENST00000537460.1 ENST00000450214.2 ENST00000545270.1 ENST00000538980.1 ENST00000542018.1 ENST00000543393.1 |
RAP1B
|
RAP1B, member of RAS oncogene family |
| chr3_+_184033135 | 13.35 |
ENST00000424196.1
|
EIF4G1
|
eukaryotic translation initiation factor 4 gamma, 1 |
| chr17_-_42276574 | 13.15 |
ENST00000589805.1
|
ATXN7L3
|
ataxin 7-like 3 |
| chr15_-_65477637 | 13.11 |
ENST00000300107.3
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit |
| chr1_+_155178481 | 12.92 |
ENST00000368376.3
|
MTX1
|
metaxin 1 |
| chr8_-_101734308 | 12.61 |
ENST00000519004.1
ENST00000519363.1 ENST00000520142.1 |
PABPC1
|
poly(A) binding protein, cytoplasmic 1 |
| chr11_-_57103327 | 12.32 |
ENST00000529002.1
ENST00000278412.2 |
SSRP1
|
structure specific recognition protein 1 |
| chrX_+_70503037 | 12.02 |
ENST00000535149.1
|
NONO
|
non-POU domain containing, octamer-binding |
| chr21_-_40720974 | 11.43 |
ENST00000380748.1
|
HMGN1
|
high mobility group nucleosome binding domain 1 |
| chr6_-_24721054 | 11.05 |
ENST00000378119.4
|
C6orf62
|
chromosome 6 open reading frame 62 |
| chr2_-_230786679 | 10.58 |
ENST00000543084.1
ENST00000343290.5 ENST00000389044.4 ENST00000283943.5 |
TRIP12
|
thyroid hormone receptor interactor 12 |
| chr10_+_114709999 | 10.50 |
ENST00000355995.4
ENST00000545257.1 ENST00000543371.1 ENST00000536810.1 ENST00000355717.4 ENST00000538897.1 ENST00000534894.1 |
TCF7L2
|
transcription factor 7-like 2 (T-cell specific, HMG-box) |
| chr17_+_7788104 | 10.49 |
ENST00000380358.4
|
CHD3
|
chromodomain helicase DNA binding protein 3 |
| chr17_-_80231300 | 10.37 |
ENST00000398519.5
ENST00000580446.1 |
CSNK1D
|
casein kinase 1, delta |
| chr16_+_29817841 | 10.35 |
ENST00000322945.6
ENST00000562337.1 ENST00000566906.2 ENST00000563402.1 ENST00000219782.6 |
MAZ
|
MYC-associated zinc finger protein (purine-binding transcription factor) |
| chr21_-_40720995 | 10.33 |
ENST00000380749.5
|
HMGN1
|
high mobility group nucleosome binding domain 1 |
| chr8_-_17104356 | 10.23 |
ENST00000361272.4
ENST00000523917.1 |
CNOT7
|
CCR4-NOT transcription complex, subunit 7 |
| chr19_-_36233332 | 9.93 |
ENST00000592537.1
ENST00000246532.1 ENST00000344990.3 ENST00000588992.1 |
IGFLR1
|
IGF-like family receptor 1 |
| chr1_+_155178518 | 9.88 |
ENST00000316721.4
|
MTX1
|
metaxin 1 |
| chr1_-_67896095 | 9.86 |
ENST00000370994.4
|
SERBP1
|
SERPINE1 mRNA binding protein 1 |
| chr19_-_46476791 | 9.82 |
ENST00000263257.5
|
NOVA2
|
neuro-oncological ventral antigen 2 |
| chr12_-_111180644 | 9.54 |
ENST00000551676.1
ENST00000550991.1 ENST00000335007.5 ENST00000340766.5 |
PPP1CC
|
protein phosphatase 1, catalytic subunit, gamma isozyme |
| chr1_-_67896069 | 9.35 |
ENST00000370995.2
ENST00000361219.6 |
SERBP1
|
SERPINE1 mRNA binding protein 1 |
| chrX_+_123094672 | 9.29 |
ENST00000354548.5
ENST00000458700.1 |
STAG2
|
stromal antigen 2 |
| chr16_+_67063036 | 9.17 |
ENST00000290858.6
ENST00000564034.1 |
CBFB
|
core-binding factor, beta subunit |
| chr10_-_12084770 | 9.17 |
ENST00000357604.5
|
UPF2
|
UPF2 regulator of nonsense transcripts homolog (yeast) |
| chr4_-_111119804 | 9.12 |
ENST00000394607.3
ENST00000302274.3 |
ELOVL6
|
ELOVL fatty acid elongase 6 |
| chr15_-_61521495 | 9.07 |
ENST00000335670.6
|
RORA
|
RAR-related orphan receptor A |
| chr19_+_14672755 | 9.06 |
ENST00000594545.1
|
TECR
|
trans-2,3-enoyl-CoA reductase |
| chr17_-_56065484 | 9.04 |
ENST00000581208.1
|
VEZF1
|
vascular endothelial zinc finger 1 |
| chr1_+_41445413 | 9.00 |
ENST00000541520.1
|
CTPS1
|
CTP synthase 1 |
| chr19_-_39330818 | 8.92 |
ENST00000594769.1
ENST00000602021.1 |
AC104534.3
|
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial |
| chr7_+_106809406 | 8.86 |
ENST00000468410.1
ENST00000478930.1 ENST00000464009.1 ENST00000222574.4 |
HBP1
|
HMG-box transcription factor 1 |
| chr5_+_49962495 | 8.85 |
ENST00000515175.1
|
PARP8
|
poly (ADP-ribose) polymerase family, member 8 |
| chr6_+_34204642 | 8.84 |
ENST00000347617.6
ENST00000401473.3 ENST00000311487.5 ENST00000447654.1 ENST00000395004.3 |
HMGA1
|
high mobility group AT-hook 1 |
| chr1_+_26856236 | 8.83 |
ENST00000374168.2
ENST00000374166.4 |
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| chrX_+_123095546 | 8.66 |
ENST00000371157.3
ENST00000371145.3 ENST00000371144.3 |
STAG2
|
stromal antigen 2 |
| chr4_-_99850243 | 8.66 |
ENST00000280892.6
ENST00000511644.1 ENST00000504432.1 ENST00000505992.1 |
EIF4E
|
eukaryotic translation initiation factor 4E |
| chr9_-_20622478 | 8.58 |
ENST00000355930.6
ENST00000380338.4 |
MLLT3
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| chrX_+_70503433 | 8.56 |
ENST00000276079.8
ENST00000373856.3 ENST00000373841.1 ENST00000420903.1 |
NONO
|
non-POU domain containing, octamer-binding |
| chr17_-_62658186 | 8.54 |
ENST00000262435.9
|
SMURF2
|
SMAD specific E3 ubiquitin protein ligase 2 |
| chr16_+_67063142 | 8.54 |
ENST00000412916.2
|
CBFB
|
core-binding factor, beta subunit |
| chr15_-_69113218 | 8.53 |
ENST00000560303.1
ENST00000465139.2 |
ANP32A
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| chr14_+_24605361 | 8.50 |
ENST00000206451.6
ENST00000559123.1 |
PSME1
|
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) |
| chr6_-_41909191 | 8.45 |
ENST00000512426.1
ENST00000372987.4 |
CCND3
|
cyclin D3 |
| chr14_-_24615523 | 8.44 |
ENST00000559056.1
|
PSME2
|
proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
| chr19_+_797443 | 8.40 |
ENST00000394601.4
ENST00000589575.1 |
PTBP1
|
polypyrimidine tract binding protein 1 |
| chr10_+_21823079 | 8.30 |
ENST00000377100.3
ENST00000377072.3 ENST00000446906.2 |
MLLT10
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| chr19_+_797392 | 8.28 |
ENST00000350092.4
ENST00000349038.4 ENST00000586481.1 ENST00000585535.1 |
PTBP1
|
polypyrimidine tract binding protein 1 |
| chr1_-_151431647 | 7.88 |
ENST00000368863.2
ENST00000409503.1 ENST00000491586.1 ENST00000533351.1 ENST00000540984.1 |
POGZ
|
pogo transposable element with ZNF domain |
| chr1_-_167906020 | 7.88 |
ENST00000458574.1
|
MPC2
|
mitochondrial pyruvate carrier 2 |
| chr7_-_148581251 | 7.73 |
ENST00000478654.1
ENST00000460911.1 ENST00000350995.2 |
EZH2
|
enhancer of zeste homolog 2 (Drosophila) |
| chr2_+_181845843 | 7.72 |
ENST00000602710.1
|
UBE2E3
|
ubiquitin-conjugating enzyme E2E 3 |
| chrX_+_123094369 | 7.68 |
ENST00000455404.1
ENST00000218089.9 |
STAG2
|
stromal antigen 2 |
| chr1_-_111746966 | 7.66 |
ENST00000369752.5
|
DENND2D
|
DENN/MADD domain containing 2D |
| chr8_-_101963677 | 7.56 |
ENST00000395956.3
ENST00000395953.2 |
YWHAZ
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| chr1_+_93544821 | 7.50 |
ENST00000370303.4
|
MTF2
|
metal response element binding transcription factor 2 |
| chr14_-_75643296 | 7.48 |
ENST00000303575.4
|
TMED10
|
transmembrane emp24-like trafficking protein 10 (yeast) |
| chr3_+_157823609 | 7.44 |
ENST00000480820.1
|
RSRC1
|
arginine/serine-rich coiled-coil 1 |
| chr4_+_154387480 | 7.42 |
ENST00000409663.3
ENST00000440693.1 ENST00000409959.3 |
KIAA0922
|
KIAA0922 |
| chr13_-_52027134 | 7.38 |
ENST00000311234.4
ENST00000425000.1 ENST00000463928.1 ENST00000442263.3 ENST00000398119.2 |
INTS6
|
integrator complex subunit 6 |
| chr17_+_65821636 | 7.38 |
ENST00000544778.2
|
BPTF
|
bromodomain PHD finger transcription factor |
| chr18_+_29672573 | 7.34 |
ENST00000578107.1
ENST00000257190.5 ENST00000580499.1 |
RNF138
|
ring finger protein 138, E3 ubiquitin protein ligase |
| chr12_-_54653313 | 7.32 |
ENST00000550411.1
ENST00000439541.2 |
CBX5
|
chromobox homolog 5 |
| chr11_+_85955787 | 7.07 |
ENST00000528180.1
|
EED
|
embryonic ectoderm development |
| chr12_-_57505121 | 7.05 |
ENST00000538913.2
ENST00000537215.2 ENST00000454075.3 ENST00000554825.1 ENST00000553275.1 ENST00000300134.3 |
STAT6
|
signal transducer and activator of transcription 6, interleukin-4 induced |
| chr19_-_39108552 | 7.05 |
ENST00000591517.1
|
MAP4K1
|
mitogen-activated protein kinase kinase kinase kinase 1 |
| chr8_-_57123815 | 7.03 |
ENST00000316981.3
ENST00000423799.2 ENST00000429357.2 |
PLAG1
|
pleiomorphic adenoma gene 1 |
| chr7_-_148581360 | 7.01 |
ENST00000320356.2
ENST00000541220.1 ENST00000483967.1 ENST00000536783.1 |
EZH2
|
enhancer of zeste homolog 2 (Drosophila) |
| chr11_+_64009072 | 6.99 |
ENST00000535135.1
ENST00000394540.3 |
FKBP2
|
FK506 binding protein 2, 13kDa |
| chr6_+_31633902 | 6.96 |
ENST00000375865.2
ENST00000375866.2 |
CSNK2B
|
casein kinase 2, beta polypeptide |
| chr6_+_32936353 | 6.92 |
ENST00000374825.4
|
BRD2
|
bromodomain containing 2 |
| chr1_+_155179012 | 6.91 |
ENST00000609421.1
|
MTX1
|
metaxin 1 |
| chr17_-_36413133 | 6.85 |
ENST00000523089.1
ENST00000312412.4 ENST00000520237.1 |
RP11-1407O15.2
|
TBC1 domain family member 3 |
| chr14_-_21905395 | 6.80 |
ENST00000430710.3
ENST00000553283.1 |
CHD8
|
chromodomain helicase DNA binding protein 8 |
| chr3_+_179280668 | 6.79 |
ENST00000429709.2
ENST00000450518.2 ENST00000392662.1 ENST00000490364.1 |
ACTL6A
|
actin-like 6A |
| chr1_+_155036204 | 6.75 |
ENST00000368409.3
ENST00000359751.4 ENST00000427683.2 ENST00000556931.1 ENST00000505139.1 |
EFNA4
EFNA3
EFNA3
|
ephrin-A4 ephrin-A3 Ephrin-A3; Uncharacterized protein; cDNA FLJ57652, highly similar to Ephrin-A3 |
| chr12_+_54378923 | 6.71 |
ENST00000303460.4
|
HOXC10
|
homeobox C10 |
| chr1_-_53018654 | 6.69 |
ENST00000257177.4
ENST00000355809.4 ENST00000528642.1 ENST00000470626.1 ENST00000371544.3 |
ZCCHC11
|
zinc finger, CCHC domain containing 11 |
| chr17_-_77813186 | 6.61 |
ENST00000448310.1
ENST00000269397.4 |
CBX4
|
chromobox homolog 4 |
| chr11_-_63933504 | 6.58 |
ENST00000255681.6
|
MACROD1
|
MACRO domain containing 1 |
| chr4_-_140098339 | 6.50 |
ENST00000394235.2
|
ELF2
|
E74-like factor 2 (ets domain transcription factor) |
| chr13_-_31040060 | 6.50 |
ENST00000326004.4
ENST00000341423.5 |
HMGB1
|
high mobility group box 1 |
| chr16_+_30675654 | 6.47 |
ENST00000287468.5
ENST00000395073.2 |
FBRS
|
fibrosin |
| chr13_-_31039375 | 6.46 |
ENST00000399494.1
|
HMGB1
|
high mobility group box 1 |
| chr1_+_26737292 | 6.44 |
ENST00000254231.4
|
LIN28A
|
lin-28 homolog A (C. elegans) |
| chr11_+_34073269 | 6.42 |
ENST00000389645.3
|
CAPRIN1
|
cell cycle associated protein 1 |
| chr7_+_23146271 | 6.29 |
ENST00000545771.1
|
KLHL7
|
kelch-like family member 7 |
| chr17_+_7155343 | 6.26 |
ENST00000573513.1
ENST00000354429.2 ENST00000574255.1 ENST00000396627.2 ENST00000356683.2 |
ELP5
|
elongator acetyltransferase complex subunit 5 |
| chr1_+_27022485 | 6.25 |
ENST00000324856.7
|
ARID1A
|
AT rich interactive domain 1A (SWI-like) |
| chr12_-_9913489 | 6.19 |
ENST00000228434.3
ENST00000536709.1 |
CD69
|
CD69 molecule |
| chr1_+_26737253 | 6.18 |
ENST00000326279.6
|
LIN28A
|
lin-28 homolog A (C. elegans) |
| chr22_+_41347363 | 6.18 |
ENST00000216225.8
|
RBX1
|
ring-box 1, E3 ubiquitin protein ligase |
| chr1_+_116184566 | 6.17 |
ENST00000355485.2
ENST00000369510.4 |
VANGL1
|
VANGL planar cell polarity protein 1 |
| chr19_-_39108643 | 6.08 |
ENST00000396857.2
|
MAP4K1
|
mitogen-activated protein kinase kinase kinase kinase 1 |
| chr2_-_48132924 | 6.07 |
ENST00000403359.3
|
FBXO11
|
F-box protein 11 |
| chr3_+_5020801 | 6.05 |
ENST00000256495.3
|
BHLHE40
|
basic helix-loop-helix family, member e40 |
| chr8_-_124428569 | 6.01 |
ENST00000521903.1
|
ATAD2
|
ATPase family, AAA domain containing 2 |
| chr10_-_13390270 | 5.99 |
ENST00000378614.4
ENST00000545675.1 ENST00000327347.5 |
SEPHS1
|
selenophosphate synthetase 1 |
| chr8_+_26149007 | 5.86 |
ENST00000380737.3
ENST00000524169.1 |
PPP2R2A
|
protein phosphatase 2, regulatory subunit B, alpha |
| chr19_-_39108568 | 5.84 |
ENST00000586296.1
|
MAP4K1
|
mitogen-activated protein kinase kinase kinase kinase 1 |
| chr17_-_4269768 | 5.84 |
ENST00000396981.2
|
UBE2G1
|
ubiquitin-conjugating enzyme E2G 1 |
| chr15_-_43785303 | 5.80 |
ENST00000382039.3
ENST00000450115.2 ENST00000382044.4 |
TP53BP1
|
tumor protein p53 binding protein 1 |
| chr6_+_42749759 | 5.76 |
ENST00000314073.5
|
GLTSCR1L
|
GLTSCR1-like |
| chr17_+_37618257 | 5.72 |
ENST00000447079.4
|
CDK12
|
cyclin-dependent kinase 12 |
| chr12_-_6716569 | 5.71 |
ENST00000544040.1
ENST00000545942.1 |
CHD4
|
chromodomain helicase DNA binding protein 4 |
| chr16_-_31021921 | 5.69 |
ENST00000215095.5
|
STX1B
|
syntaxin 1B |
| chr8_-_101963482 | 5.68 |
ENST00000419477.2
|
YWHAZ
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| chr1_-_211752073 | 5.61 |
ENST00000367001.4
|
SLC30A1
|
solute carrier family 30 (zinc transporter), member 1 |
| chrX_-_129244454 | 5.59 |
ENST00000308167.5
|
ELF4
|
E74-like factor 4 (ets domain transcription factor) |
| chr20_+_47662805 | 5.59 |
ENST00000262982.2
ENST00000542325.1 |
CSE1L
|
CSE1 chromosome segregation 1-like (yeast) |
| chr22_-_19165917 | 5.57 |
ENST00000451283.1
|
SLC25A1
|
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 |
| chr6_+_31633833 | 5.57 |
ENST00000375882.2
ENST00000375880.2 |
CSNK2B
CSNK2B-LY6G5B-1181
|
casein kinase 2, beta polypeptide Uncharacterized protein |
| chr1_-_115259337 | 5.57 |
ENST00000369535.4
|
NRAS
|
neuroblastoma RAS viral (v-ras) oncogene homolog |
| chr7_-_154794763 | 5.56 |
ENST00000404141.1
|
PAXIP1
|
PAX interacting (with transcription-activation domain) protein 1 |
| chr17_+_65821780 | 5.55 |
ENST00000321892.4
ENST00000335221.5 ENST00000306378.6 |
BPTF
|
bromodomain PHD finger transcription factor |
| chr5_+_133861339 | 5.54 |
ENST00000282605.4
ENST00000361895.2 ENST00000402835.1 |
PHF15
|
jade family PHD finger 2 |
| chr14_-_38064198 | 5.53 |
ENST00000250448.2
|
FOXA1
|
forkhead box A1 |
| chr14_+_53173910 | 5.52 |
ENST00000606149.1
ENST00000555339.1 ENST00000556813.1 |
PSMC6
|
proteasome (prosome, macropain) 26S subunit, ATPase, 6 |
| chr20_+_61427797 | 5.52 |
ENST00000370487.3
|
MRGBP
|
MRG/MORF4L binding protein |
| chrX_-_129244655 | 5.51 |
ENST00000335997.7
|
ELF4
|
E74-like factor 4 (ets domain transcription factor) |
| chr7_-_154794621 | 5.48 |
ENST00000419436.1
ENST00000397192.1 |
PAXIP1
|
PAX interacting (with transcription-activation domain) protein 1 |
| chr12_-_6716534 | 5.48 |
ENST00000544484.1
ENST00000309577.6 ENST00000357008.2 |
CHD4
|
chromodomain helicase DNA binding protein 4 |
| chr11_+_34073195 | 5.46 |
ENST00000341394.4
|
CAPRIN1
|
cell cycle associated protein 1 |
| chr17_-_46688334 | 5.43 |
ENST00000239165.7
|
HOXB7
|
homeobox B7 |
| chr17_-_42297092 | 5.39 |
ENST00000393606.3
|
UBTF
|
upstream binding transcription factor, RNA polymerase I |
| chr17_+_42634844 | 5.38 |
ENST00000315323.3
|
FZD2
|
frizzled family receptor 2 |
| chr16_-_31021717 | 5.36 |
ENST00000565419.1
|
STX1B
|
syntaxin 1B |
| chr5_+_133707252 | 5.35 |
ENST00000506787.1
ENST00000507277.1 |
UBE2B
|
ubiquitin-conjugating enzyme E2B |
| chr17_+_45608614 | 5.33 |
ENST00000544660.1
|
NPEPPS
|
aminopeptidase puromycin sensitive |
| chr14_+_53173890 | 5.32 |
ENST00000445930.2
|
PSMC6
|
proteasome (prosome, macropain) 26S subunit, ATPase, 6 |
| chr1_-_38273840 | 5.28 |
ENST00000373044.2
|
YRDC
|
yrdC N(6)-threonylcarbamoyltransferase domain containing |
| chr17_+_46985731 | 5.22 |
ENST00000360943.5
|
UBE2Z
|
ubiquitin-conjugating enzyme E2Z |
| chr12_+_53845879 | 5.19 |
ENST00000359282.5
ENST00000603815.1 ENST00000447282.1 ENST00000437231.1 ENST00000549863.1 ENST00000359462.5 ENST00000550520.2 ENST00000546463.1 ENST00000552296.2 |
PCBP2
|
poly(rC) binding protein 2 |
| chr17_-_42143963 | 5.13 |
ENST00000585388.1
ENST00000293406.3 |
LSM12
|
LSM12 homolog (S. cerevisiae) |
| chr17_-_7297833 | 5.11 |
ENST00000571802.1
ENST00000576201.1 ENST00000573213.1 ENST00000324822.11 |
TMEM256-PLSCR3
|
TMEM256-PLSCR3 readthrough (NMD candidate) |
| chr1_+_47799446 | 5.08 |
ENST00000371873.5
|
CMPK1
|
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic |
| chr12_-_120907374 | 5.06 |
ENST00000550458.1
|
SRSF9
|
serine/arginine-rich splicing factor 9 |
| chr9_+_110045537 | 5.06 |
ENST00000358015.3
|
RAD23B
|
RAD23 homolog B (S. cerevisiae) |
| chr6_+_20403997 | 5.04 |
ENST00000535432.1
|
E2F3
|
E2F transcription factor 3 |
| chr8_+_57124245 | 5.00 |
ENST00000521831.1
ENST00000355315.3 ENST00000303759.3 ENST00000517636.1 ENST00000517933.1 ENST00000518801.1 ENST00000523975.1 ENST00000396723.5 ENST00000523061.1 ENST00000521524.1 |
CHCHD7
|
coiled-coil-helix-coiled-coil-helix domain containing 7 |
| chr1_+_32479430 | 5.00 |
ENST00000327300.7
ENST00000492989.1 |
KHDRBS1
|
KH domain containing, RNA binding, signal transduction associated 1 |
| chrX_-_70474910 | 4.94 |
ENST00000373988.1
ENST00000373998.1 |
ZMYM3
|
zinc finger, MYM-type 3 |
| chr11_-_85779971 | 4.93 |
ENST00000393346.3
|
PICALM
|
phosphatidylinositol binding clathrin assembly protein |
| chrX_+_40944871 | 4.91 |
ENST00000378308.2
ENST00000324545.8 |
USP9X
|
ubiquitin specific peptidase 9, X-linked |
| chr2_-_20425158 | 4.90 |
ENST00000381150.1
|
SDC1
|
syndecan 1 |
| chr5_-_137674000 | 4.84 |
ENST00000510119.1
ENST00000513970.1 |
CDC25C
|
cell division cycle 25C |
| chr10_+_70661014 | 4.83 |
ENST00000373585.3
|
DDX50
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 |
| chr3_+_197677047 | 4.82 |
ENST00000448864.1
|
RPL35A
|
ribosomal protein L35a |
| chr12_+_122242597 | 4.74 |
ENST00000267197.5
|
SETD1B
|
SET domain containing 1B |
| chr10_+_70091847 | 4.72 |
ENST00000441000.2
ENST00000354695.5 |
HNRNPH3
|
heterogeneous nuclear ribonucleoprotein H3 (2H9) |
| chrX_-_118827333 | 4.71 |
ENST00000360156.7
ENST00000354228.4 ENST00000489216.1 ENST00000354416.3 ENST00000394610.1 ENST00000343984.5 |
SEPT6
|
septin 6 |
| chr19_-_17356697 | 4.69 |
ENST00000291442.3
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6 |
| chr10_+_21823243 | 4.67 |
ENST00000307729.7
ENST00000377091.2 |
MLLT10
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| chr17_-_7154984 | 4.58 |
ENST00000574322.1
|
CTDNEP1
|
CTD nuclear envelope phosphatase 1 |
| chr1_+_2985760 | 4.57 |
ENST00000378391.2
ENST00000514189.1 ENST00000270722.5 |
PRDM16
|
PR domain containing 16 |
| chr7_-_150675372 | 4.56 |
ENST00000262186.5
|
KCNH2
|
potassium voltage-gated channel, subfamily H (eag-related), member 2 |
| chrX_-_152989798 | 4.55 |
ENST00000441714.1
ENST00000442093.1 ENST00000429550.1 ENST00000345046.6 |
BCAP31
|
B-cell receptor-associated protein 31 |
| chrX_+_47441712 | 4.54 |
ENST00000218388.4
ENST00000377018.2 ENST00000456754.2 ENST00000377017.1 ENST00000441738.1 |
TIMP1
|
TIMP metallopeptidase inhibitor 1 |
| chr20_+_57466357 | 4.52 |
ENST00000371095.3
ENST00000371085.3 ENST00000354359.7 ENST00000265620.7 |
GNAS
|
GNAS complex locus |
| chr19_+_11071685 | 4.52 |
ENST00000541122.2
ENST00000589677.1 ENST00000444061.3 |
SMARCA4
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| chr16_+_3074002 | 4.51 |
ENST00000326266.8
ENST00000574549.1 ENST00000575576.1 ENST00000253952.9 |
THOC6
|
THO complex 6 homolog (Drosophila) |
| chr7_+_23145884 | 4.46 |
ENST00000409689.1
ENST00000410047.1 |
KLHL7
|
kelch-like family member 7 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF740_ZNF219
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.8 | 29.4 | GO:0016260 | selenocysteine biosynthetic process(GO:0016260) |
| 9.6 | 66.9 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 5.8 | 23.3 | GO:1902361 | mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361) |
| 5.4 | 21.5 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 4.9 | 14.7 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 4.8 | 33.9 | GO:1900045 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 4.1 | 20.5 | GO:0003408 | optic cup formation involved in camera-type eye development(GO:0003408) |
| 3.9 | 19.3 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 3.9 | 34.7 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 3.4 | 24.1 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 3.4 | 20.6 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 3.4 | 13.7 | GO:0019860 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860) intestinal epithelial cell maturation(GO:0060574) |
| 3.4 | 20.3 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 3.2 | 13.0 | GO:2000426 | plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) |
| 3.1 | 156.8 | GO:0043486 | histone exchange(GO:0043486) |
| 3.0 | 9.0 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 2.8 | 22.2 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 2.8 | 11.0 | GO:1903422 | negative regulation of synaptic vesicle recycling(GO:1903422) |
| 2.4 | 9.5 | GO:0015746 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 2.3 | 18.2 | GO:0042761 | fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761) |
| 2.2 | 11.1 | GO:0007070 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
| 2.2 | 8.8 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 2.2 | 6.6 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 2.2 | 15.3 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 2.1 | 19.3 | GO:0072718 | response to cisplatin(GO:0072718) |
| 2.1 | 8.5 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 2.0 | 6.1 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
| 2.0 | 10.1 | GO:0021759 | globus pallidus development(GO:0021759) |
| 1.9 | 20.6 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 1.9 | 7.5 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 1.8 | 5.3 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 1.8 | 10.5 | GO:0044334 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 1.7 | 10.2 | GO:0072553 | terminal button organization(GO:0072553) |
| 1.7 | 1.7 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 1.6 | 4.9 | GO:0048627 | myoblast development(GO:0048627) |
| 1.6 | 11.4 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 1.6 | 14.5 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 1.6 | 12.5 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 1.5 | 4.6 | GO:1902303 | regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303) |
| 1.5 | 10.2 | GO:0060339 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) negative regulation of type I interferon-mediated signaling pathway(GO:0060339) |
| 1.4 | 4.3 | GO:0097254 | renal tubular secretion(GO:0097254) |
| 1.4 | 4.3 | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 1.4 | 4.2 | GO:0045014 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
| 1.4 | 5.5 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 1.3 | 3.9 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 1.3 | 21.9 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 1.3 | 8.8 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 1.3 | 13.9 | GO:1905247 | positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247) |
| 1.2 | 5.0 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 1.2 | 12.3 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 1.2 | 3.5 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 1.2 | 3.5 | GO:0035283 | rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
| 1.1 | 4.5 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 1.1 | 5.6 | GO:0097501 | regulation of sequestering of zinc ion(GO:0061088) detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501) |
| 1.1 | 11.1 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 1.1 | 20.7 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 1.1 | 7.6 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 1.0 | 7.3 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 1.0 | 8.4 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 1.0 | 3.1 | GO:1902161 | positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) |
| 1.0 | 5.1 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 1.0 | 5.0 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 1.0 | 3.9 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.9 | 2.8 | GO:0061010 | gall bladder development(GO:0061010) |
| 0.9 | 5.5 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.9 | 12.8 | GO:0021702 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.9 | 4.6 | GO:1904154 | positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 0.9 | 3.6 | GO:0021773 | striatal medium spiny neuron differentiation(GO:0021773) |
| 0.9 | 13.2 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.9 | 6.8 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.8 | 4.2 | GO:0097350 | neutrophil clearance(GO:0097350) |
| 0.8 | 6.6 | GO:1902659 | regulation of glucose mediated signaling pathway(GO:1902659) |
| 0.8 | 2.5 | GO:0090219 | negative regulation of lipid kinase activity(GO:0090219) |
| 0.8 | 2.4 | GO:0061009 | regulation of mitotic cell cycle, embryonic(GO:0009794) midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558) mitotic cell cycle, embryonic(GO:0045448) common bile duct development(GO:0061009) |
| 0.8 | 3.2 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 0.8 | 2.3 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 0.8 | 23.4 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.8 | 3.0 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.7 | 3.0 | GO:1904046 | negative regulation of vascular endothelial growth factor production(GO:1904046) |
| 0.7 | 3.7 | GO:0030047 | actin modification(GO:0030047) |
| 0.7 | 5.8 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.7 | 13.5 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.7 | 3.5 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 0.7 | 2.7 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.7 | 19.5 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 0.7 | 5.4 | GO:0003150 | muscular septum morphogenesis(GO:0003150) |
| 0.7 | 6.0 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.7 | 2.0 | GO:1904327 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 0.6 | 7.1 | GO:0072498 | embryonic skeletal joint development(GO:0072498) |
| 0.6 | 4.5 | GO:1905049 | negative regulation of metallopeptidase activity(GO:1905049) |
| 0.6 | 13.8 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.6 | 5.6 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.6 | 1.9 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 0.6 | 6.2 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.6 | 4.7 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
| 0.6 | 7.5 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.6 | 4.6 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.6 | 1.7 | GO:0048295 | positive regulation of isotype switching to IgE isotypes(GO:0048295) |
| 0.6 | 6.8 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.6 | 5.1 | GO:0000717 | nucleotide-excision repair, DNA duplex unwinding(GO:0000717) |
| 0.6 | 5.0 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.6 | 20.1 | GO:0045589 | regulation of regulatory T cell differentiation(GO:0045589) |
| 0.6 | 21.2 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.6 | 2.2 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.5 | 4.4 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.5 | 7.0 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
| 0.5 | 50.2 | GO:0016575 | histone deacetylation(GO:0016575) |
| 0.5 | 1.6 | GO:0014707 | branchiomeric skeletal muscle development(GO:0014707) |
| 0.5 | 8.3 | GO:0035246 | peptidyl-arginine N-methylation(GO:0035246) |
| 0.5 | 6.8 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.5 | 1.5 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.5 | 2.9 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.5 | 2.9 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 0.5 | 1.4 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
| 0.5 | 10.8 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.5 | 1.8 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 0.4 | 12.0 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.4 | 5.3 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 0.4 | 4.8 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
| 0.4 | 11.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.4 | 3.8 | GO:0006983 | ER overload response(GO:0006983) |
| 0.4 | 15.4 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.4 | 0.8 | GO:0000432 | regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) |
| 0.4 | 7.8 | GO:0005975 | carbohydrate metabolic process(GO:0005975) |
| 0.4 | 7.8 | GO:0000052 | citrulline metabolic process(GO:0000052) |
| 0.4 | 1.6 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.4 | 2.0 | GO:1900125 | regulation of hyaluronan biosynthetic process(GO:1900125) |
| 0.4 | 1.6 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 0.4 | 12.0 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.4 | 33.3 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 0.4 | 30.7 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.4 | 1.5 | GO:0090107 | regulation of high-density lipoprotein particle assembly(GO:0090107) |
| 0.4 | 8.1 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.4 | 7.4 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.4 | 2.9 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.3 | 3.8 | GO:0071455 | cellular response to hyperoxia(GO:0071455) |
| 0.3 | 3.8 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.3 | 1.7 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.3 | 2.4 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.3 | 6.3 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.3 | 3.9 | GO:0042921 | glucocorticoid receptor signaling pathway(GO:0042921) |
| 0.3 | 1.3 | GO:0007566 | embryo implantation(GO:0007566) |
| 0.3 | 1.2 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
| 0.3 | 8.1 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 0.3 | 2.8 | GO:0019375 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.3 | 5.9 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.3 | 5.7 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.3 | 3.3 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.3 | 41.5 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.3 | 0.8 | GO:0021919 | BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919) |
| 0.3 | 1.7 | GO:0003012 | muscle system process(GO:0003012) |
| 0.3 | 6.3 | GO:0030220 | platelet formation(GO:0030220) |
| 0.3 | 13.6 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.3 | 1.3 | GO:1903672 | positive regulation of sprouting angiogenesis(GO:1903672) |
| 0.3 | 16.1 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.3 | 0.5 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
| 0.2 | 3.7 | GO:0031268 | pseudopodium organization(GO:0031268) |
| 0.2 | 1.7 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) |
| 0.2 | 3.7 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.2 | 2.1 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.2 | 0.9 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) |
| 0.2 | 17.6 | GO:0071427 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.2 | 0.7 | GO:0032900 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 0.2 | 3.1 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.2 | 0.7 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 0.2 | 8.1 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.2 | 6.9 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
| 0.2 | 4.8 | GO:1902751 | positive regulation of cell cycle G2/M phase transition(GO:1902751) |
| 0.2 | 1.2 | GO:1903659 | regulation of complement-dependent cytotoxicity(GO:1903659) |
| 0.2 | 0.8 | GO:1902969 | mitotic DNA replication(GO:1902969) |
| 0.2 | 2.4 | GO:0061098 | positive regulation of protein tyrosine kinase activity(GO:0061098) |
| 0.2 | 2.1 | GO:1901673 | regulation of mitotic spindle assembly(GO:1901673) ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 0.2 | 9.4 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.2 | 0.7 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
| 0.2 | 3.2 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.2 | 2.6 | GO:0010225 | response to UV-C(GO:0010225) |
| 0.2 | 2.9 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 0.2 | 1.2 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
| 0.2 | 0.6 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 0.2 | 1.5 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.2 | 1.1 | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
| 0.2 | 5.6 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.1 | 3.8 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.1 | 1.4 | GO:0098719 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.1 | 0.4 | GO:0061760 | antifungal innate immune response(GO:0061760) |
| 0.1 | 1.7 | GO:0060087 | relaxation of vascular smooth muscle(GO:0060087) |
| 0.1 | 3.1 | GO:0002335 | mature B cell differentiation(GO:0002335) |
| 0.1 | 10.5 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.1 | 1.7 | GO:0098727 | stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727) |
| 0.1 | 19.1 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.1 | 4.2 | GO:0071174 | mitotic spindle checkpoint(GO:0071174) |
| 0.1 | 4.0 | GO:2001222 | regulation of neuron migration(GO:2001222) |
| 0.1 | 1.2 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.1 | 0.6 | GO:0070885 | negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) |
| 0.1 | 0.7 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.1 | 4.5 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.1 | 1.9 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
| 0.1 | 5.4 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.1 | 6.3 | GO:0035065 | regulation of histone acetylation(GO:0035065) |
| 0.1 | 1.0 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.1 | 6.6 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.1 | 2.3 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.1 | 0.8 | GO:0001878 | response to yeast(GO:0001878) |
| 0.1 | 0.6 | GO:0002034 | regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) negative regulation of plasminogen activation(GO:0010757) |
| 0.1 | 4.3 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 7.5 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.1 | 0.6 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.1 | 1.7 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.1 | 1.2 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 1.3 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.1 | 1.8 | GO:1901998 | toxin transport(GO:1901998) |
| 0.1 | 0.3 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.1 | 1.2 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
| 0.1 | 6.7 | GO:0006446 | regulation of translational initiation(GO:0006446) |
| 0.1 | 0.5 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.1 | 0.5 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.1 | 0.2 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
| 0.1 | 0.7 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.1 | 0.3 | GO:0055005 | ventricular cardiac myofibril assembly(GO:0055005) |
| 0.1 | 20.2 | GO:0006260 | DNA replication(GO:0006260) |
| 0.1 | 2.6 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.1 | 1.0 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.1 | 1.4 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.1 | 0.1 | GO:0009886 | post-embryonic morphogenesis(GO:0009886) post-embryonic eye morphogenesis(GO:0048050) post-embryonic organ morphogenesis(GO:0048563) post-embryonic organ development(GO:0048569) |
| 0.1 | 1.6 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 1.7 | GO:0072348 | sulfur compound transport(GO:0072348) |
| 0.1 | 3.8 | GO:0071349 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
| 0.1 | 1.2 | GO:0006511 | ubiquitin-dependent protein catabolic process(GO:0006511) |
| 0.1 | 4.8 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.1 | 1.0 | GO:0032354 | response to follicle-stimulating hormone(GO:0032354) |
| 0.1 | 8.0 | GO:0010952 | positive regulation of peptidase activity(GO:0010952) |
| 0.1 | 0.2 | GO:1902748 | melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748) |
| 0.1 | 0.4 | GO:0035810 | positive regulation of urine volume(GO:0035810) |
| 0.0 | 0.8 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.0 | 3.6 | GO:0036498 | IRE1-mediated unfolded protein response(GO:0036498) |
| 0.0 | 2.7 | GO:0008344 | adult locomotory behavior(GO:0008344) |
| 0.0 | 0.9 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
| 0.0 | 4.7 | GO:0043473 | pigmentation(GO:0043473) |
| 0.0 | 3.8 | GO:0007292 | female gamete generation(GO:0007292) |
| 0.0 | 0.2 | GO:0090245 | axis elongation involved in somitogenesis(GO:0090245) |
| 0.0 | 1.6 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.1 | GO:0035564 | regulation of kidney size(GO:0035564) regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623) |
| 0.0 | 0.7 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
| 0.0 | 0.4 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
| 0.0 | 0.6 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.0 | 17.0 | GO:0042493 | response to drug(GO:0042493) |
| 0.0 | 0.4 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.0 | 2.1 | GO:0010608 | posttranscriptional regulation of gene expression(GO:0010608) |
| 0.0 | 1.2 | GO:0006939 | smooth muscle contraction(GO:0006939) |
| 0.0 | 0.2 | GO:0045880 | positive regulation of smoothened signaling pathway(GO:0045880) |
| 0.0 | 0.4 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 0.0 | 0.9 | GO:0060976 | coronary vasculature development(GO:0060976) |
| 0.0 | 0.6 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.0 | 0.5 | GO:0045061 | thymic T cell selection(GO:0045061) |
| 0.0 | 2.6 | GO:0070268 | cornification(GO:0070268) |
| 0.0 | 0.7 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.7 | GO:0090398 | cellular senescence(GO:0090398) |
| 0.0 | 1.9 | GO:0050817 | blood coagulation(GO:0007596) hemostasis(GO:0007599) coagulation(GO:0050817) |
| 0.0 | 0.4 | GO:0048147 | negative regulation of fibroblast proliferation(GO:0048147) |
| 0.0 | 0.2 | GO:0032965 | regulation of collagen biosynthetic process(GO:0032965) positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.0 | 1.7 | GO:0055072 | iron ion homeostasis(GO:0055072) |
| 0.0 | 0.1 | GO:0070120 | ciliary neurotrophic factor-mediated signaling pathway(GO:0070120) |
| 0.0 | 0.2 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.0 | 2.3 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
| 0.0 | 0.2 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.0 | 0.1 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
| 0.0 | 2.0 | GO:0000910 | cytokinesis(GO:0000910) |
| 0.0 | 0.3 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 0.1 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.0 | 0.3 | GO:2000352 | negative regulation of endothelial cell apoptotic process(GO:2000352) |
| 0.0 | 0.3 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
| 0.0 | 0.8 | GO:0032355 | response to estradiol(GO:0032355) |
| 0.0 | 0.2 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.9 | 63.1 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 6.3 | 133.1 | GO:0000812 | Swr1 complex(GO:0000812) |
| 5.4 | 32.4 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 3.2 | 45.1 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 2.6 | 13.1 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 2.6 | 20.6 | GO:0042382 | paraspeckles(GO:0042382) |
| 2.6 | 10.2 | GO:0044094 | host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 2.4 | 16.7 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 2.2 | 11.0 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 2.1 | 6.2 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
| 2.0 | 23.9 | GO:0005642 | annulate lamellae(GO:0005642) |
| 1.9 | 32.7 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 1.8 | 12.9 | GO:0016589 | NURF complex(GO:0016589) |
| 1.8 | 10.5 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 1.7 | 25.6 | GO:0045120 | pronucleus(GO:0045120) |
| 1.6 | 39.4 | GO:0071564 | npBAF complex(GO:0071564) |
| 1.6 | 4.8 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 1.4 | 2.8 | GO:0031213 | RSF complex(GO:0031213) |
| 1.4 | 29.8 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 1.3 | 3.8 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 1.3 | 16.4 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 1.2 | 69.6 | GO:1990391 | DNA repair complex(GO:1990391) |
| 1.2 | 6.1 | GO:0033503 | HULC complex(GO:0033503) |
| 1.2 | 7.1 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 1.0 | 11.1 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 1.0 | 11.0 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 1.0 | 9.5 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.9 | 4.6 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 0.9 | 10.8 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.8 | 23.3 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.8 | 7.4 | GO:0032039 | integrator complex(GO:0032039) |
| 0.8 | 8.8 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.8 | 5.5 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.8 | 3.1 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.8 | 4.6 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.8 | 11.4 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.7 | 3.7 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.7 | 6.7 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.7 | 17.3 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.7 | 4.2 | GO:0033643 | host cell part(GO:0033643) |
| 0.7 | 6.3 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.7 | 4.7 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.6 | 4.5 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.6 | 1.8 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.6 | 8.0 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.6 | 9.0 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.6 | 5.9 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.6 | 5.7 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.5 | 2.7 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.5 | 7.3 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.5 | 2.0 | GO:0072379 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.5 | 1.4 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.4 | 5.7 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.4 | 3.8 | GO:0005638 | lamin filament(GO:0005638) |
| 0.4 | 52.5 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.4 | 18.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.4 | 1.6 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 0.4 | 7.0 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.4 | 5.0 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.4 | 6.5 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.4 | 6.3 | GO:0032059 | bleb(GO:0032059) |
| 0.3 | 7.2 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.3 | 1.3 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.3 | 5.7 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.3 | 35.7 | GO:0016605 | PML body(GO:0016605) |
| 0.3 | 5.8 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.3 | 2.1 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.2 | 16.0 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.2 | 2.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.2 | 4.3 | GO:0005901 | caveola(GO:0005901) |
| 0.2 | 2.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.2 | 3.0 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.2 | 1.7 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.2 | 1.9 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.2 | 8.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.2 | 0.6 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.2 | 0.6 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 0.2 | 2.6 | GO:0097346 | INO80-type complex(GO:0097346) |
| 0.2 | 14.6 | GO:0005811 | lipid particle(GO:0005811) |
| 0.2 | 1.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.2 | 5.5 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.2 | 2.8 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.2 | 1.7 | GO:0042555 | MCM complex(GO:0042555) |
| 0.2 | 16.7 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.2 | 54.5 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.2 | 3.5 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 3.7 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 5.0 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 6.1 | GO:0016235 | aggresome(GO:0016235) |
| 0.1 | 4.3 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 23.9 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.1 | 84.6 | GO:0016604 | nuclear body(GO:0016604) |
| 0.1 | 0.7 | GO:0002177 | manchette(GO:0002177) |
| 0.1 | 7.8 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.1 | 1.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 1.6 | GO:0005903 | brush border(GO:0005903) |
| 0.1 | 1.7 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.1 | 6.2 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 1.7 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 2.8 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 1.5 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 11.7 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.1 | 0.4 | GO:0001741 | XY body(GO:0001741) |
| 0.1 | 3.8 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.1 | 1.4 | GO:0030904 | retromer complex(GO:0030904) |
| 0.1 | 10.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 3.0 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.1 | 7.3 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.1 | 2.4 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.1 | 5.6 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.1 | 1.6 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.1 | 4.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 4.8 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 4.4 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.0 | 4.2 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 4.5 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 4.2 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 1.3 | GO:0097546 | ciliary base(GO:0097546) |
| 0.0 | 0.2 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.0 | 1.0 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 0.7 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.2 | GO:0070554 | synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 0.0 | 1.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 7.8 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 1.2 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.8 | 29.4 | GO:0004756 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
| 4.6 | 32.4 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 4.2 | 37.8 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 3.0 | 9.0 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 2.9 | 26.4 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 2.9 | 32.1 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 2.9 | 23.3 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 2.4 | 9.5 | GO:0015137 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 2.3 | 124.4 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 2.3 | 9.1 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 2.2 | 64.9 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 2.2 | 13.0 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 2.0 | 34.7 | GO:0008494 | translation activator activity(GO:0008494) |
| 1.9 | 26.3 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 1.7 | 6.7 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 1.6 | 13.1 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 1.6 | 7.8 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 1.5 | 9.1 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 1.5 | 3.0 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 1.4 | 7.1 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 1.4 | 5.5 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 1.4 | 78.0 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 1.3 | 17.0 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 1.3 | 9.1 | GO:0008142 | oxysterol binding(GO:0008142) |
| 1.2 | 7.5 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 1.2 | 17.7 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 1.1 | 5.6 | GO:0050436 | microfibril binding(GO:0050436) |
| 1.1 | 8.7 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 1.0 | 3.1 | GO:0005260 | channel-conductance-controlling ATPase activity(GO:0005260) |
| 1.0 | 14.5 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 1.0 | 21.7 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 1.0 | 51.9 | GO:0031491 | nucleosome binding(GO:0031491) |
| 1.0 | 10.8 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 1.0 | 7.8 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 1.0 | 5.8 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 1.0 | 16.4 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.9 | 6.6 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.9 | 4.6 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.9 | 5.2 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.8 | 5.1 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 0.8 | 95.9 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.8 | 14.1 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.8 | 2.3 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 0.8 | 4.6 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673) |
| 0.7 | 10.1 | GO:0044213 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.7 | 2.8 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.7 | 12.8 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.7 | 30.7 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.7 | 7.6 | GO:0051430 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.7 | 2.7 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.7 | 8.9 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.7 | 8.8 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 0.7 | 6.8 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.7 | 11.8 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.6 | 3.8 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.6 | 5.0 | GO:0098599 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.6 | 2.3 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.6 | 25.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.6 | 8.3 | GO:0016274 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 0.5 | 3.0 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.5 | 13.2 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.5 | 7.8 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.5 | 3.7 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.5 | 2.8 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
| 0.5 | 1.8 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.4 | 1.3 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.4 | 4.3 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.4 | 8.6 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.4 | 2.5 | GO:0030548 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.4 | 2.9 | GO:0043426 | MRF binding(GO:0043426) |
| 0.4 | 9.4 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.4 | 34.6 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.4 | 6.6 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.4 | 1.5 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 0.4 | 6.3 | GO:0005522 | profilin binding(GO:0005522) |
| 0.3 | 1.7 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.3 | 3.5 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.3 | 2.4 | GO:0030021 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.3 | 5.9 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.3 | 1.4 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.3 | 1.7 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.3 | 9.5 | GO:0005521 | lamin binding(GO:0005521) |
| 0.3 | 7.1 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.3 | 3.7 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.3 | 2.3 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.3 | 1.3 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.3 | 4.7 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.3 | 2.7 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.3 | 4.2 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.3 | 13.6 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.3 | 5.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.3 | 3.8 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.3 | 2.6 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.3 | 2.3 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.3 | 3.1 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.3 | 2.2 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.3 | 6.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.3 | 9.2 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.3 | 6.3 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.3 | 5.7 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.3 | 3.1 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.3 | 8.8 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.2 | 11.0 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.2 | 1.7 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.2 | 6.9 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.2 | 2.4 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.2 | 13.9 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.2 | 15.8 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.2 | 5.8 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.2 | 10.1 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.2 | 2.0 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.2 | 2.2 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.2 | 7.9 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.2 | 1.5 | GO:0032393 | MHC class I receptor activity(GO:0032393) |
| 0.2 | 1.2 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.2 | 44.9 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.2 | 3.8 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.2 | 3.8 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.2 | 2.0 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.2 | 1.6 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.2 | 8.5 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.2 | 1.1 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.2 | 1.4 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.2 | 6.4 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.1 | 12.3 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.1 | 1.4 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 2.9 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 3.1 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 7.7 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 1.7 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.1 | 0.8 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.1 | 4.2 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.1 | 4.6 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.1 | 1.9 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
| 0.1 | 13.5 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.1 | 5.0 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 0.6 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.1 | 0.4 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
| 0.1 | 1.8 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 2.8 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 0.8 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.1 | 1.1 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.1 | 0.4 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.1 | 0.9 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.1 | 0.3 | GO:0070984 | SET domain binding(GO:0070984) |
| 0.1 | 2.6 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 0.5 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.1 | 4.0 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.1 | 0.8 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.1 | 0.3 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.1 | 0.7 | GO:0005113 | patched binding(GO:0005113) |
| 0.1 | 1.7 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.1 | 6.1 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 0.5 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.1 | 0.4 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.1 | 0.9 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.1 | 2.7 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.1 | 4.3 | GO:0008186 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.1 | 2.3 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 0.7 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.1 | 0.5 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 0.7 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 0.1 | 2.0 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.1 | 5.0 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.1 | 0.4 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.1 | 0.6 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.1 | 0.9 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 6.0 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 2.1 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.1 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.0 | 0.4 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 1.8 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.0 | 1.7 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.2 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.0 | 0.4 | GO:0031404 | chloride ion binding(GO:0031404) |
| 0.0 | 3.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.9 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 5.8 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 0.8 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 1.6 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 1.5 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 0.2 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.0 | 0.9 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 0.1 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 1.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 14.5 | GO:0003723 | RNA binding(GO:0003723) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 26.2 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.9 | 21.4 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.8 | 70.2 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.7 | 35.5 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.7 | 22.8 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.6 | 16.7 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.6 | 68.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.5 | 11.1 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.5 | 30.5 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.5 | 8.7 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.4 | 2.2 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.4 | 8.9 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.4 | 17.6 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.4 | 13.0 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.4 | 6.3 | PID MYC PATHWAY | C-MYC pathway |
| 0.4 | 20.0 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.4 | 48.5 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.3 | 3.2 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.3 | 11.8 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.3 | 7.1 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.2 | 15.1 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.2 | 5.6 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.2 | 7.5 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.2 | 14.3 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.2 | 14.8 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.2 | 4.5 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.2 | 5.8 | PID ATM PATHWAY | ATM pathway |
| 0.2 | 13.8 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.2 | 4.4 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.2 | 2.4 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.2 | 6.9 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.2 | 3.8 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.2 | 7.8 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.2 | 10.5 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.2 | 9.3 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.2 | 8.8 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.2 | 3.7 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 6.3 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.1 | 6.5 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 3.7 | PID BMP PATHWAY | BMP receptor signaling |
| 0.1 | 1.3 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.1 | 4.6 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 1.1 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 2.0 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.1 | 1.5 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 0.9 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 2.6 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.0 | 0.7 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.8 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 1.7 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.5 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.3 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 0.3 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 0.4 | ST ADRENERGIC | Adrenergic Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 67.7 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 1.8 | 21.5 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 1.5 | 72.7 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 1.1 | 31.3 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 1.0 | 27.7 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 1.0 | 8.8 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.8 | 16.1 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.7 | 113.4 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.7 | 10.1 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.7 | 49.9 | REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
| 0.6 | 5.6 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.6 | 30.6 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.6 | 27.5 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.5 | 13.7 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.5 | 8.7 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.5 | 29.3 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.5 | 5.1 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.4 | 3.9 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.4 | 38.3 | REACTOME RNA POL I TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |
| 0.4 | 24.6 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.4 | 11.0 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.4 | 11.0 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.4 | 67.0 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.4 | 5.6 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.3 | 6.6 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.3 | 5.5 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.3 | 14.0 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.3 | 4.1 | REACTOME SIGNALING BY NOTCH3 | Genes involved in Signaling by NOTCH3 |
| 0.3 | 5.6 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.2 | 6.5 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.2 | 4.9 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.2 | 6.0 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.2 | 4.3 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.2 | 2.5 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.2 | 4.0 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.2 | 7.7 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.2 | 0.7 | REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | Genes involved in TGF-beta receptor signaling activates SMADs |
| 0.2 | 7.7 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.2 | 5.1 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.2 | 4.3 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.2 | 9.0 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.1 | 2.3 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 2.2 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.1 | 10.0 | REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | Genes involved in trans-Golgi Network Vesicle Budding |
| 0.1 | 4.5 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 2.8 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 10.7 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 4.3 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 6.7 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.1 | 4.9 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 2.2 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 0.8 | REACTOME ARMS MEDIATED ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.1 | 1.5 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 1.7 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.1 | 14.0 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.1 | 1.6 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.1 | 0.9 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 0.4 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.1 | 2.3 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 2.1 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.4 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 3.1 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 1.9 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 1.7 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 1.0 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 2.2 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 0.3 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.0 | 1.4 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |