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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AAGGCAC

Z-value: 1.45

Motif logo

logo of

miRNA associated with seed AAGGCAC

NamemiRBASE accession
hsa-miR-124-3p.1
MIMAT0000422

Activity profile of AAGGCAC motif

Sorted Z-values of AAGGCAC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_33246722 22.95 ENST00000437302.1
ENST00000396033.2
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr10_+_17271266 22.55 ENST00000224237.5
VIM
vimentin
chr2_-_161350305 21.55 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr1_+_182992545 17.40 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr1_+_223900034 17.39 ENST00000295006.5
CAPN2
calpain 2, (m/II) large subunit
chr21_-_44846999 16.64 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr22_-_50746027 16.45 ENST00000425954.1
ENST00000449103.1
PLXNB2
plexin B2
chr2_-_64881018 16.30 ENST00000313349.3
SERTAD2
SERTA domain containing 2
chr3_-_120170052 15.81 ENST00000295633.3
FSTL1
follistatin-like 1
chr2_+_109204909 15.68 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_+_138725343 15.22 ENST00000607197.1
ENST00000367697.3
HEBP2
heme binding protein 2
chr1_-_154943212 15.20 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr4_-_122618095 14.87 ENST00000515017.1
ENST00000501272.2
ENST00000296511.5
ANXA5
annexin A5
chr7_+_116165754 14.79 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr19_-_50143452 13.49 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr7_+_98972298 13.47 ENST00000252725.5
ARPC1B
actin related protein 2/3 complex, subunit 1B, 41kDa
chr9_-_110251836 13.18 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr22_-_36784035 13.10 ENST00000216181.5
MYH9
myosin, heavy chain 9, non-muscle
chr12_-_58146048 12.97 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
CDK4
cyclin-dependent kinase 4
chr6_-_36515177 12.86 ENST00000229812.7
STK38
serine/threonine kinase 38
chr7_+_17338239 12.85 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chr15_-_101792137 12.78 ENST00000254190.3
CHSY1
chondroitin sulfate synthase 1
chr19_+_39138271 12.46 ENST00000252699.2
ACTN4
actinin, alpha 4
chr2_-_37899323 12.33 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr12_-_65146636 12.05 ENST00000418919.2
GNS
glucosamine (N-acetyl)-6-sulfatase
chrX_-_109561294 11.89 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr8_-_49833978 11.83 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr15_-_55562582 11.62 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr19_+_797392 11.52 ENST00000350092.4
ENST00000349038.4
ENST00000586481.1
ENST00000585535.1
PTBP1
polypyrimidine tract binding protein 1
chr6_-_109703663 11.50 ENST00000368961.5
CD164
CD164 molecule, sialomucin
chr11_+_60681346 11.02 ENST00000227525.3
TMEM109
transmembrane protein 109
chr5_+_65440032 10.79 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr10_-_30024716 10.34 ENST00000375398.2
ENST00000375400.3
SVIL
supervillin
chr5_+_149340282 10.26 ENST00000286298.4
SLC26A2
solute carrier family 26 (anion exchanger), member 2
chr5_+_82767284 10.23 ENST00000265077.3
VCAN
versican
chr16_-_84651673 10.19 ENST00000262428.4
COTL1
coactosin-like 1 (Dictyostelium)
chr7_+_77166592 10.17 ENST00000248594.6
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr14_+_70078303 10.17 ENST00000342745.4
KIAA0247
KIAA0247
chr12_-_15942309 10.04 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr7_-_6523755 10.01 ENST00000436575.1
ENST00000258739.4
DAGLB
KDELR2
diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr11_+_832944 10.01 ENST00000322008.4
ENST00000397421.1
ENST00000529810.1
ENST00000526693.1
ENST00000525333.1
ENST00000524748.1
ENST00000527341.1
CD151
CD151 molecule (Raph blood group)
chr16_+_69221028 9.98 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr8_+_98656336 9.96 ENST00000336273.3
MTDH
metadherin
chr2_+_69969106 9.96 ENST00000409920.1
ENST00000394295.4
ENST00000536030.1
ANXA4
annexin A4
chr1_+_165796753 9.93 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr7_+_66386204 9.93 ENST00000341567.4
ENST00000607045.1
TMEM248
transmembrane protein 248
chr7_+_142960505 9.91 ENST00000409500.3
ENST00000443571.2
ENST00000358406.5
ENST00000479303.1
GSTK1
glutathione S-transferase kappa 1
chr3_+_69812877 9.71 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr15_+_90931450 9.50 ENST00000268182.5
ENST00000560738.1
ENST00000560418.1
IQGAP1
IQ motif containing GTPase activating protein 1
chr10_-_74856608 9.28 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr17_-_7297833 9.24 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr5_-_131563501 9.22 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr1_+_110091189 9.20 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr4_+_129730779 9.16 ENST00000226319.6
PHF17
jade family PHD finger 1
chr2_+_219264466 9.14 ENST00000273062.2
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr16_-_85045131 8.88 ENST00000313732.4
ZDHHC7
zinc finger, DHHC-type containing 7
chr9_-_124132483 8.85 ENST00000286713.2
ENST00000538954.1
ENST00000347359.2
STOM
stomatin
chr18_+_19749386 8.82 ENST00000269216.3
GATA6
GATA binding protein 6
chr17_+_7123125 8.80 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
ACADVL
acyl-CoA dehydrogenase, very long chain
chr2_-_153574480 8.76 ENST00000410080.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr17_-_62658186 8.73 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr5_-_98262240 8.71 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr2_-_43453734 8.71 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr12_+_96588143 8.67 ENST00000228741.3
ENST00000547249.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr17_-_40540377 8.60 ENST00000404395.3
ENST00000389272.3
ENST00000585517.1
ENST00000588065.1
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr6_-_134639180 8.56 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr8_-_37756972 8.38 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr17_-_41174424 8.33 ENST00000355653.3
VAT1
vesicle amine transport 1
chr3_-_182698381 8.31 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr15_+_45315302 8.29 ENST00000267814.9
SORD
sorbitol dehydrogenase
chr5_+_172410757 8.23 ENST00000519374.1
ENST00000519911.1
ENST00000265093.4
ENST00000517669.1
ATP6V0E1
ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
chr2_+_28615669 8.22 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr10_+_89419370 8.20 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr7_+_106809406 8.17 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1
HMG-box transcription factor 1
chr20_+_361261 8.15 ENST00000217233.3
TRIB3
tribbles pseudokinase 3
chr5_-_39425068 8.14 ENST00000515700.1
ENST00000339788.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr6_-_4135825 8.12 ENST00000380118.3
ENST00000413766.2
ENST00000361538.2
ECI2
enoyl-CoA delta isomerase 2
chr11_-_22851367 8.08 ENST00000354193.4
SVIP
small VCP/p97-interacting protein
chrX_+_49028265 8.02 ENST00000376322.3
ENST00000376327.5
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr10_-_3827417 8.01 ENST00000497571.1
ENST00000542957.1
KLF6
Kruppel-like factor 6
chrX_+_123095155 7.96 ENST00000371160.1
ENST00000435103.1
STAG2
stromal antigen 2
chr6_+_7107999 7.90 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr6_-_86352642 7.90 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr6_+_143929307 7.88 ENST00000427704.2
ENST00000305766.6
PHACTR2
phosphatase and actin regulator 2
chr1_-_225840747 7.82 ENST00000366843.2
ENST00000366844.3
ENAH
enabled homolog (Drosophila)
chr3_+_37903432 7.72 ENST00000443503.2
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr10_-_81965307 7.63 ENST00000537102.1
ENST00000372231.3
ENST00000438331.1
ENST00000422982.3
ENST00000360615.4
ENST00000265447.4
ANXA11
annexin A11
chr6_+_16129308 7.59 ENST00000356840.3
ENST00000349606.4
MYLIP
myosin regulatory light chain interacting protein
chr5_+_75699040 7.57 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chr20_-_43977055 7.50 ENST00000372733.3
ENST00000537976.1
SDC4
syndecan 4
chrX_+_41192595 7.47 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr1_-_150947343 7.44 ENST00000271688.6
ENST00000368954.5
CERS2
ceramide synthase 2
chr2_+_88991162 7.42 ENST00000283646.4
RPIA
ribose 5-phosphate isomerase A
chr1_-_38325256 7.39 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr16_+_67063036 7.30 ENST00000290858.6
ENST00000564034.1
CBFB
core-binding factor, beta subunit
chr20_-_10654639 7.29 ENST00000254958.5
JAG1
jagged 1
chr6_+_37137939 7.27 ENST00000373509.5
PIM1
pim-1 oncogene
chr6_-_13814663 7.24 ENST00000359495.2
ENST00000379170.4
MCUR1
mitochondrial calcium uniporter regulator 1
chr18_+_29077990 7.23 ENST00000261590.8
DSG2
desmoglein 2
chr3_-_133969437 7.18 ENST00000460933.1
ENST00000296084.4
RYK
receptor-like tyrosine kinase
chr8_+_98881268 7.17 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2
matrilin 2
chr16_-_11680791 7.14 ENST00000571976.1
ENST00000413364.2
LITAF
lipopolysaccharide-induced TNF factor
chr6_+_56954867 7.02 ENST00000370708.4
ENST00000370702.1
ZNF451
zinc finger protein 451
chr2_+_178257372 7.00 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr5_+_151151471 6.99 ENST00000394123.3
ENST00000543466.1
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr14_+_103058948 6.95 ENST00000262241.6
RCOR1
REST corepressor 1
chr1_+_64058939 6.89 ENST00000371084.3
PGM1
phosphoglucomutase 1
chr1_-_222885770 6.87 ENST00000355727.2
ENST00000340020.6
AIDA
axin interactor, dorsalization associated
chr12_-_58240470 6.77 ENST00000548823.1
ENST00000398073.2
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chrX_-_77150985 6.76 ENST00000358075.6
MAGT1
magnesium transporter 1
chr10_-_33623564 6.75 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr17_+_28705921 6.75 ENST00000225719.4
CPD
carboxypeptidase D
chr19_-_45908292 6.73 ENST00000360957.5
ENST00000592134.1
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr7_-_100860851 6.69 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr20_+_49126881 6.69 ENST00000371621.3
ENST00000541713.1
PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr1_+_193091080 6.69 ENST00000367435.3
CDC73
cell division cycle 73
chr3_-_72496035 6.69 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr14_+_21538429 6.61 ENST00000298694.4
ENST00000555038.1
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chrX_+_131157290 6.59 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chr1_+_40723779 6.55 ENST00000372759.3
ZMPSTE24
zinc metallopeptidase STE24
chr6_-_41909561 6.54 ENST00000372991.4
CCND3
cyclin D3
chr3_-_160283348 6.51 ENST00000334256.4
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr9_+_137218362 6.51 ENST00000481739.1
RXRA
retinoid X receptor, alpha
chr21_+_35445827 6.47 ENST00000608209.1
ENST00000381151.3
SLC5A3
SLC5A3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr10_-_27443155 6.36 ENST00000427324.1
ENST00000326799.3
YME1L1
YME1-like 1 ATPase
chr1_+_26856236 6.33 ENST00000374168.2
ENST00000374166.4
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr21_-_46293586 6.31 ENST00000445724.2
ENST00000397887.3
PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr7_+_39663061 6.31 ENST00000005257.2
RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr19_-_42759300 6.30 ENST00000222329.4
ERF
Ets2 repressor factor
chr2_+_46769798 6.30 ENST00000238738.4
RHOQ
ras homolog family member Q
chr9_+_123970052 6.27 ENST00000373823.3
GSN
gelsolin
chr9_+_114423615 6.26 ENST00000374293.4
GNG10
guanine nucleotide binding protein (G protein), gamma 10
chr12_+_111843749 6.24 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr7_-_105162652 6.24 ENST00000356362.2
ENST00000469408.1
PUS7
pseudouridylate synthase 7 homolog (S. cerevisiae)
chr20_+_42086525 6.22 ENST00000244020.3
SRSF6
serine/arginine-rich splicing factor 6
chr8_+_110346546 6.22 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
ENY2
enhancer of yellow 2 homolog (Drosophila)
chrX_-_10645773 6.20 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr1_+_36348790 6.17 ENST00000373204.4
AGO1
argonaute RISC catalytic component 1
chr6_-_52441713 6.17 ENST00000182527.3
TRAM2
translocation associated membrane protein 2
chr10_+_72575643 6.10 ENST00000373202.3
SGPL1
sphingosine-1-phosphate lyase 1
chr3_+_152879985 6.08 ENST00000323534.2
RAP2B
RAP2B, member of RAS oncogene family
chr5_+_122110691 6.05 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2
sorting nexin 2
chr7_-_27183263 6.00 ENST00000222726.3
HOXA5
homeobox A5
chr12_+_104359576 5.99 ENST00000392872.3
ENST00000436021.2
TDG
thymine-DNA glycosylase
chr6_+_35995488 5.98 ENST00000229795.3
MAPK14
mitogen-activated protein kinase 14
chr2_-_26467557 5.91 ENST00000380649.3
HADHA
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
chr12_+_121124599 5.81 ENST00000228506.3
MLEC
malectin
chr19_-_33793430 5.77 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr3_+_5229356 5.76 ENST00000256497.4
EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr1_+_32645269 5.76 ENST00000373610.3
TXLNA
taxilin alpha
chr22_-_26986045 5.74 ENST00000442495.1
ENST00000440953.1
ENST00000450022.1
ENST00000338754.4
TPST2
tyrosylprotein sulfotransferase 2
chr19_-_10697895 5.70 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr1_+_112162381 5.69 ENST00000433097.1
ENST00000369709.3
ENST00000436150.2
RAP1A
RAP1A, member of RAS oncogene family
chr21_-_34852304 5.69 ENST00000542230.2
TMEM50B
transmembrane protein 50B
chr1_+_7831323 5.63 ENST00000054666.6
VAMP3
vesicle-associated membrane protein 3
chr17_+_57784826 5.58 ENST00000262291.4
VMP1
vacuole membrane protein 1
chr1_+_173446405 5.56 ENST00000340385.5
PRDX6
peroxiredoxin 6
chr1_-_115259337 5.54 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr8_+_56014949 5.53 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr4_-_54930790 5.50 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr16_+_447209 5.49 ENST00000382940.4
ENST00000219479.2
NME4
NME/NM23 nucleoside diphosphate kinase 4
chr6_-_79787902 5.49 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr10_-_75173785 5.45 ENST00000535178.1
ENST00000372921.5
ENST00000372919.4
ANXA7
annexin A7
chr1_+_116184566 5.41 ENST00000355485.2
ENST00000369510.4
VANGL1
VANGL planar cell polarity protein 1
chrX_+_9983602 5.41 ENST00000380861.4
WWC3
WWC family member 3
chr5_-_131826457 5.37 ENST00000437654.1
ENST00000245414.4
IRF1
interferon regulatory factor 1
chr11_+_64948665 5.35 ENST00000533820.1
CAPN1
calpain 1, (mu/I) large subunit
chr20_+_48552908 5.34 ENST00000244061.2
RNF114
ring finger protein 114
chr11_+_125462690 5.34 ENST00000392708.4
ENST00000529196.1
ENST00000531491.1
STT3A
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr5_-_137878887 5.33 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr1_+_47799446 5.32 ENST00000371873.5
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr3_+_187930719 5.26 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr20_+_61569463 5.23 ENST00000266069.3
GID8
GID complex subunit 8
chr5_-_133968529 5.21 ENST00000402673.2
SAR1B
SAR1 homolog B (S. cerevisiae)
chr7_-_137686791 5.20 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
CREB3L2
cAMP responsive element binding protein 3-like 2
chr8_+_95732095 5.18 ENST00000414645.2
DPY19L4
dpy-19-like 4 (C. elegans)
chr6_+_12012536 5.18 ENST00000379388.2
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr18_-_18691739 5.11 ENST00000399799.2
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr11_+_76494253 5.07 ENST00000333090.4
TSKU
tsukushi, small leucine rich proteoglycan
chr22_-_50946113 5.04 ENST00000216080.5
ENST00000474879.2
ENST00000380796.3
LMF2
lipase maturation factor 2
chr19_+_10828724 5.04 ENST00000585892.1
ENST00000314646.5
ENST00000359692.6
DNM2
dynamin 2
chr1_-_236228403 5.03 ENST00000366595.3
NID1
nidogen 1
chr22_+_21996549 5.03 ENST00000248958.4
SDF2L1
stromal cell-derived factor 2-like 1
chr11_+_20385327 4.99 ENST00000451739.2
ENST00000532505.1
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr1_-_16482554 4.98 ENST00000358432.5
EPHA2
EPH receptor A2
chr2_-_152684977 4.94 ENST00000428992.2
ENST00000295087.8
ARL5A
ADP-ribosylation factor-like 5A
chr10_+_72164135 4.90 ENST00000373218.4
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr10_+_88516396 4.86 ENST00000372037.3
BMPR1A
bone morphogenetic protein receptor, type IA
chr3_+_180630090 4.81 ENST00000357559.4
ENST00000305586.7
FXR1
fragile X mental retardation, autosomal homolog 1
chr6_-_53213780 4.73 ENST00000304434.6
ENST00000370918.4
ELOVL5
ELOVL fatty acid elongase 5
chr2_-_97405775 4.71 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L
lectin, mannose-binding 2-like
chr13_-_110959478 4.69 ENST00000543140.1
ENST00000375820.4
COL4A1
collagen, type IV, alpha 1
chr1_+_224544552 4.66 ENST00000465271.1
ENST00000366858.3
CNIH4
cornichon family AMPA receptor auxiliary protein 4
chr5_+_109025067 4.66 ENST00000261483.4
MAN2A1
mannosidase, alpha, class 2A, member 1
chr12_+_1800179 4.65 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr1_-_95392635 4.64 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr11_-_87908600 4.61 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chr2_-_26101374 4.61 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr2_-_174830430 4.60 ENST00000310015.6
ENST00000455789.2
SP3
Sp3 transcription factor
chr18_-_19284724 4.58 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of AAGGCAC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 5.0 GO:0051604 protein maturation(GO:0051604)
4.9 14.8 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
4.6 23.0 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161) regulation of collagen catabolic process(GO:0010710)
4.4 13.2 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
4.4 13.1 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
4.2 16.6 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
4.2 12.5 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
4.1 12.4 GO:0061073 ciliary body morphogenesis(GO:0061073)
4.0 12.0 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
3.9 11.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
3.7 18.5 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
3.7 11.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
3.1 3.1 GO:0060926 cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
3.1 21.7 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
2.8 2.8 GO:0035826 hypotonic response(GO:0006971) rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476) regulation of rubidium ion transport(GO:2000680) negative regulation of rubidium ion transport(GO:2000681) regulation of rubidium ion transmembrane transporter activity(GO:2000686) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
2.8 2.8 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
2.8 8.3 GO:0006059 hexitol metabolic process(GO:0006059)
2.7 8.0 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
2.6 5.2 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
2.5 10.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
2.5 9.9 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
2.5 7.4 GO:0006014 D-ribose metabolic process(GO:0006014)
2.4 4.9 GO:0048382 mesendoderm development(GO:0048382)
2.4 7.3 GO:0030327 prenylated protein catabolic process(GO:0030327)
2.4 14.3 GO:2000644 regulation of receptor catabolic process(GO:2000644)
2.3 7.0 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
2.2 6.7 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
2.2 8.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
2.2 15.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
2.2 6.5 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
2.2 8.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
2.1 8.5 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
2.1 8.3 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
2.0 8.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
2.0 8.1 GO:0035026 leading edge cell differentiation(GO:0035026)
2.0 13.8 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
2.0 7.9 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
1.9 11.6 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
1.9 5.7 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
1.9 5.7 GO:0097327 response to antineoplastic agent(GO:0097327)
1.9 7.5 GO:0042256 mature ribosome assembly(GO:0042256)
1.9 20.4 GO:0070307 lens fiber cell development(GO:0070307)
1.8 7.2 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
1.7 5.2 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.7 1.7 GO:1901420 negative regulation of response to alcohol(GO:1901420)
1.7 5.1 GO:0003383 apical constriction(GO:0003383)
1.7 5.0 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
1.5 3.1 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
1.5 7.5 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
1.5 6.0 GO:1902544 oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
1.5 4.5 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
1.5 7.4 GO:0014012 peripheral nervous system axon regeneration(GO:0014012) negative regulation of glial cell migration(GO:1903976)
1.5 7.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
1.4 7.2 GO:0003164 His-Purkinje system development(GO:0003164)
1.4 5.8 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
1.4 10.0 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
1.4 6.8 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
1.3 8.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
1.3 5.4 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
1.3 4.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
1.3 3.9 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
1.3 6.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.3 3.8 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
1.3 6.3 GO:1903923 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) protein processing in phagocytic vesicle(GO:1900756) regulation of plasma membrane raft polarization(GO:1903906) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
1.2 18.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
1.2 2.4 GO:1901656 glycoside transport(GO:1901656)
1.2 8.6 GO:0070294 renal sodium ion absorption(GO:0070294)
1.2 6.0 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
1.2 3.5 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
1.2 3.5 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
1.2 9.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
1.1 7.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
1.1 13.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015)
1.1 10.0 GO:0006621 protein retention in ER lumen(GO:0006621)
1.1 3.3 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
1.1 31.8 GO:0031581 hemidesmosome assembly(GO:0031581)
1.0 6.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
1.0 4.0 GO:0016240 autophagosome docking(GO:0016240)
1.0 6.9 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
1.0 5.9 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.9 12.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.9 2.8 GO:1900081 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.9 2.8 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.9 3.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.9 7.3 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.9 1.8 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.9 5.4 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.9 6.3 GO:0051665 membrane raft localization(GO:0051665)
0.9 1.8 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.9 8.9 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.9 1.8 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.9 6.2 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.9 8.8 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.9 12.3 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
0.9 7.0 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.9 7.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.9 17.4 GO:0016540 protein autoprocessing(GO:0016540)
0.9 4.3 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.8 1.7 GO:1904747 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.8 14.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.8 2.5 GO:0008050 female courtship behavior(GO:0008050)
0.8 3.3 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.8 0.8 GO:0060594 mammary gland specification(GO:0060594)
0.8 2.5 GO:2000276 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.8 2.5 GO:1901143 insulin catabolic process(GO:1901143)
0.8 7.4 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.8 3.3 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.8 4.7 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.8 3.1 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.8 1.6 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.8 5.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.8 4.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.8 4.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.7 2.2 GO:0006172 ADP biosynthetic process(GO:0006172)
0.7 2.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.7 5.8 GO:0060056 mammary gland involution(GO:0060056)
0.7 5.1 GO:0015677 copper ion import(GO:0015677)
0.7 8.0 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.7 2.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.7 5.6 GO:0060155 platelet dense granule organization(GO:0060155)
0.7 3.5 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.7 6.9 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.7 2.1 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.7 2.7 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.7 6.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.7 6.8 GO:0015791 polyol transport(GO:0015791)
0.7 2.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.7 4.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.6 3.2 GO:0015862 uridine transport(GO:0015862)
0.6 0.6 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.6 19.7 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.6 6.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.6 13.0 GO:0003334 keratinocyte development(GO:0003334)
0.6 1.9 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.6 6.1 GO:0019388 galactose catabolic process(GO:0019388)
0.6 1.8 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.6 6.7 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.6 1.2 GO:0060061 Spemann organizer formation(GO:0060061)
0.6 3.0 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.6 3.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.6 7.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.6 3.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.6 3.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.6 9.4 GO:0045116 protein neddylation(GO:0045116)
0.6 4.7 GO:0006013 mannose metabolic process(GO:0006013)
0.6 5.8 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.6 2.3 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.6 20.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.5 3.3 GO:0006021 inositol biosynthetic process(GO:0006021)
0.5 1.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.5 10.1 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.5 20.1 GO:0046039 GTP metabolic process(GO:0046039)
0.5 22.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.5 1.6 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.5 7.6 GO:0032506 cytokinetic process(GO:0032506)
0.5 1.5 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.5 5.0 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.5 3.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.5 6.8 GO:0001522 pseudouridine synthesis(GO:0001522)
0.5 6.8 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.5 18.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.5 2.9 GO:0048254 snoRNA localization(GO:0048254)
0.5 1.4 GO:0060166 olfactory pit development(GO:0060166)
0.5 3.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.5 0.9 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.5 3.3 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.5 5.1 GO:0007028 cytoplasm organization(GO:0007028)
0.5 6.4 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.4 5.8 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.4 1.8 GO:0006109 regulation of carbohydrate metabolic process(GO:0006109)
0.4 8.0 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.4 1.8 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.4 13.2 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.4 1.3 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.4 3.4 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.4 3.0 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.4 1.3 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.4 5.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.4 2.5 GO:0051643 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) secretory granule localization(GO:0032252) endoplasmic reticulum localization(GO:0051643)
0.4 3.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.4 7.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.4 11.2 GO:0060325 face morphogenesis(GO:0060325)
0.4 2.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4 2.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.4 2.8 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.4 10.3 GO:0019054 modulation by virus of host process(GO:0019054)
0.4 7.9 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.4 2.0 GO:0051208 sequestering of calcium ion(GO:0051208) release of sequestered calcium ion into cytosol(GO:0051209) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283)
0.4 2.3 GO:0032916 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.4 1.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.4 3.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.4 2.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 4.6 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.4 5.3 GO:0006449 regulation of translational termination(GO:0006449)
0.4 5.3 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.4 1.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.4 3.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.4 3.7 GO:0071383 steroid hormone mediated signaling pathway(GO:0043401) cellular response to steroid hormone stimulus(GO:0071383)
0.4 1.8 GO:1902109 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.4 6.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.4 6.7 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.3 4.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.3 1.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.3 5.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 3.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.3 1.4 GO:0010813 neuropeptide catabolic process(GO:0010813)
0.3 1.3 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.3 2.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.3 1.7 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.3 2.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.3 1.3 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.3 5.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.3 2.8 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.3 18.2 GO:0050819 negative regulation of coagulation(GO:0050819)
0.3 2.8 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.3 8.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.3 1.8 GO:0030421 defecation(GO:0030421)
0.3 1.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.3 4.0 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.3 3.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 1.5 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.3 3.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.3 2.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 11.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.3 13.0 GO:0033572 transferrin transport(GO:0033572)
0.3 9.9 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.3 5.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.3 1.4 GO:0071233 cellular response to leucine(GO:0071233)
0.3 1.4 GO:0051182 coenzyme transport(GO:0051182)
0.3 3.0 GO:0010225 response to UV-C(GO:0010225)
0.3 6.3 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.3 8.8 GO:0032465 regulation of cytokinesis(GO:0032465)
0.3 4.4 GO:0009437 carnitine metabolic process(GO:0009437)
0.3 7.3 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.3 0.5 GO:0060978 proepicardium development(GO:0003342) septum transversum development(GO:0003343) angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.3 2.4 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.3 0.8 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.3 10.2 GO:0050832 defense response to fungus(GO:0050832)
0.3 1.6 GO:0070489 T cell activation(GO:0042110) leukocyte aggregation(GO:0070486) T cell aggregation(GO:0070489) lymphocyte aggregation(GO:0071593)
0.3 4.9 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.3 4.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.3 7.9 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 5.4 GO:0009651 response to salt stress(GO:0009651)
0.2 1.2 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.2 2.0 GO:0043086 negative regulation of catalytic activity(GO:0043086)
0.2 1.0 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 10.5 GO:2000142 regulation of DNA-templated transcription, initiation(GO:2000142)
0.2 9.8 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.2 2.3 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 0.9 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.2 1.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 10.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 4.0 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 3.3 GO:0051639 actin filament network formation(GO:0051639)
0.2 12.9 GO:0030888 regulation of B cell proliferation(GO:0030888)
0.2 4.0 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.2 0.4 GO:0048539 bone marrow development(GO:0048539)
0.2 3.1 GO:0033622 integrin activation(GO:0033622)
0.2 6.0 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.2 2.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 0.8 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 0.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 3.9 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.2 4.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.2 2.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.2 1.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.2 2.7 GO:0097320 membrane tubulation(GO:0097320)
0.2 1.0 GO:0072176 nephric duct development(GO:0072176) nephric duct morphogenesis(GO:0072178)
0.2 21.7 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.2 1.9 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.2 1.3 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 1.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 2.0 GO:0060117 auditory receptor cell development(GO:0060117)
0.2 0.5 GO:0030578 PML body organization(GO:0030578)
0.2 0.9 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.2 2.0 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.2 1.9 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 1.4 GO:0046349 UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.2 2.3 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.2 1.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 2.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 1.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.2 8.0 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.2 7.7 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.2 1.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 2.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.2 0.9 GO:0090175 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.2 0.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.6 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.6 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.1 0.7 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 1.2 GO:0051597 response to methylmercury(GO:0051597)
0.1 2.0 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 4.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 5.8 GO:0046686 response to cadmium ion(GO:0046686)
0.1 0.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 3.2 GO:0006605 protein targeting(GO:0006605)
0.1 4.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 2.0 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.1 1.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.5 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.1 3.1 GO:0016577 histone demethylation(GO:0016577)
0.1 4.4 GO:0001881 receptor recycling(GO:0001881)
0.1 1.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 1.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.1 0.2 GO:0030242 pexophagy(GO:0030242)
0.1 1.6 GO:0050790 regulation of catalytic activity(GO:0050790)
0.1 1.2 GO:0032239 regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.1 1.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 4.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 1.0 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 2.8 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.1 4.0 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 4.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 3.1 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 1.0 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 3.7 GO:1903318 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.1 1.4 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 4.9 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 1.5 GO:0045109 intermediate filament organization(GO:0045109)
0.1 3.9 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.1 6.3 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 4.0 GO:0008347 glial cell migration(GO:0008347)
0.1 2.4 GO:0021983 pituitary gland development(GO:0021983)
0.1 2.4 GO:0006270 DNA replication initiation(GO:0006270)
0.1 1.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.9 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.1 0.2 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 3.9 GO:0007566 embryo implantation(GO:0007566)
0.1 1.5 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.1 1.7 GO:0010039 response to iron ion(GO:0010039)
0.1 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.9 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.1 0.1 GO:0003157 endocardium development(GO:0003157)
0.1 8.9 GO:0002576 platelet degranulation(GO:0002576)
0.1 0.5 GO:0046836 glycolipid transport(GO:0046836)
0.1 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.2 GO:0035963 cellular response to interleukin-13(GO:0035963)
0.1 2.1 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.1 1.2 GO:0002643 regulation of tolerance induction(GO:0002643)
0.1 3.4 GO:0032760 positive regulation of tumor necrosis factor production(GO:0032760)
0.1 0.1 GO:1903410 nitric oxide production involved in inflammatory response(GO:0002537) lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.1 1.3 GO:0006379 mRNA cleavage(GO:0006379)
0.1 3.9 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1 4.7 GO:0030183 B cell differentiation(GO:0030183)
0.1 1.6 GO:0014902 myotube differentiation(GO:0014902)
0.1 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.1 GO:0035973 aggrephagy(GO:0035973)
0.1 3.7 GO:0038111 interleukin-7-mediated signaling pathway(GO:0038111) response to interleukin-7(GO:0098760) cellular response to interleukin-7(GO:0098761)
0.1 7.8 GO:0030308 negative regulation of cell growth(GO:0030308)
0.1 8.7 GO:0042594 response to starvation(GO:0042594)
0.1 2.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 2.2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.6 GO:0061157 mRNA destabilization(GO:0061157)
0.0 1.3 GO:0021510 spinal cord development(GO:0021510)
0.0 0.3 GO:0002118 aggressive behavior(GO:0002118)
0.0 1.2 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 1.6 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.8 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 2.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.1 GO:0060973 pericardium morphogenesis(GO:0003344) cell migration involved in heart development(GO:0060973)
0.0 2.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.7 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.4 GO:1902001 fatty acid transmembrane transport(GO:1902001) carnitine transmembrane transport(GO:1902603)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 1.8 GO:0006968 cellular defense response(GO:0006968)
0.0 1.3 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.0 3.1 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.3 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.3 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 4.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 1.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 2.0 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.7 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 5.1 GO:0006260 DNA replication(GO:0006260)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:2000146 negative regulation of cell motility(GO:2000146)
0.0 0.3 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.8 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.3 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.2 GO:0006826 iron ion transport(GO:0006826)
0.0 1.1 GO:0001649 osteoblast differentiation(GO:0001649)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 23.0 GO:0034680 integrin alpha1-beta1 complex(GO:0034665) integrin alpha3-beta1 complex(GO:0034667) integrin alpha8-beta1 complex(GO:0034678) integrin alpha10-beta1 complex(GO:0034680)
5.0 14.9 GO:0072563 endothelial microparticle(GO:0072563)
4.4 13.1 GO:0005826 actomyosin contractile ring(GO:0005826)
4.4 17.4 GO:0005606 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
3.2 12.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
3.1 9.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
2.5 15.2 GO:0070435 Shc-EGFR complex(GO:0070435)
2.4 14.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.6 9.9 GO:0030905 retromer, tubulation complex(GO:0030905)
1.6 4.7 GO:0097447 dendritic tree(GO:0097447)
1.5 4.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
1.4 10.0 GO:0046581 intercellular canaliculus(GO:0046581)
1.3 9.1 GO:0036449 microtubule minus-end(GO:0036449)
1.2 8.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
1.2 13.4 GO:0097443 sorting endosome(GO:0097443)
1.2 34.0 GO:0031143 pseudopodium(GO:0031143)
1.2 7.1 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
1.2 9.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.2 4.7 GO:0005797 Golgi medial cisterna(GO:0005797)
1.2 3.5 GO:0044305 calyx of Held(GO:0044305)
1.2 8.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
1.1 15.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.1 7.9 GO:0097452 GAIT complex(GO:0097452)
1.1 5.5 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
1.1 3.3 GO:0071159 NF-kappaB complex(GO:0071159)
1.1 13.0 GO:0033093 Weibel-Palade body(GO:0033093)
1.0 12.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.9 4.6 GO:0031905 early endosome lumen(GO:0031905)
0.8 7.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.8 2.4 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.8 3.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.7 2.9 GO:0070761 pre-snoRNP complex(GO:0070761)
0.7 13.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.7 8.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.7 10.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.7 6.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.6 3.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.6 8.5 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.6 2.4 GO:0045160 myosin I complex(GO:0045160)
0.6 4.7 GO:0005587 collagen type IV trimer(GO:0005587)
0.6 3.5 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.6 2.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.5 5.5 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.5 3.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.5 5.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.5 11.4 GO:0042588 zymogen granule(GO:0042588)
0.5 3.6 GO:0000813 ESCRT I complex(GO:0000813)
0.5 1.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.5 6.3 GO:0030478 actin cap(GO:0030478)
0.5 2.4 GO:0071797 LUBAC complex(GO:0071797)
0.5 5.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.5 16.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.5 4.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.4 8.4 GO:0001891 phagocytic cup(GO:0001891)
0.4 1.3 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.4 1.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.4 17.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.4 1.2 GO:0005879 axonemal microtubule(GO:0005879)
0.4 6.2 GO:0000124 SAGA complex(GO:0000124)
0.4 3.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.4 2.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.4 10.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.4 8.8 GO:0071004 U2-type prespliceosome(GO:0071004)
0.4 3.0 GO:0097208 alveolar lamellar body(GO:0097208)
0.4 59.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 35.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.3 2.4 GO:0016589 NURF complex(GO:0016589)
0.3 2.3 GO:0031415 NatA complex(GO:0031415)
0.3 3.6 GO:0044754 autolysosome(GO:0044754)
0.3 1.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.3 6.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.3 13.0 GO:0002102 podosome(GO:0002102)
0.3 14.9 GO:0043034 costamere(GO:0043034)
0.3 1.3 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.3 0.9 GO:0031088 platelet dense granule membrane(GO:0031088)
0.3 1.2 GO:0097165 nuclear stress granule(GO:0097165)
0.3 9.6 GO:0030057 desmosome(GO:0030057)
0.3 8.9 GO:0000421 autophagosome membrane(GO:0000421)
0.3 3.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 5.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 4.3 GO:0001741 XY body(GO:0001741)
0.3 19.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.3 2.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 7.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 3.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 2.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.3 2.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.3 0.8 GO:0034455 t-UTP complex(GO:0034455)
0.2 3.0 GO:0005642 annulate lamellae(GO:0005642)
0.2 21.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 4.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.2 1.7 GO:0072487 MSL complex(GO:0072487)
0.2 12.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 1.4 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 6.3 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.2 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 8.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 11.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 7.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 3.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 2.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 0.8 GO:1990246 uniplex complex(GO:1990246)
0.2 29.7 GO:0001650 fibrillar center(GO:0001650)
0.2 11.8 GO:0045171 intercellular bridge(GO:0045171)
0.2 1.6 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.2 5.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 5.5 GO:0005921 gap junction(GO:0005921)
0.2 1.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 6.3 GO:0005605 basal lamina(GO:0005605)
0.2 13.6 GO:0005604 basement membrane(GO:0005604)
0.2 1.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 1.8 GO:0090543 Flemming body(GO:0090543)
0.2 6.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 1.7 GO:0005915 zonula adherens(GO:0005915)
0.2 9.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 28.1 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.2 0.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 1.7 GO:0000815 ESCRT III complex(GO:0000815)
0.2 6.0 GO:0035579 specific granule membrane(GO:0035579)
0.2 80.4 GO:0005925 focal adhesion(GO:0005925)
0.2 5.0 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.2 0.8 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.2 5.1 GO:0031941 filamentous actin(GO:0031941)
0.2 1.8 GO:0045120 pronucleus(GO:0045120)
0.1 6.9 GO:1990391 DNA repair complex(GO:1990391)
0.1 22.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 3.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 18.2 GO:0016605 PML body(GO:0016605)
0.1 2.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 11.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 37.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.1 GO:0032059 bleb(GO:0032059)
0.1 1.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 5.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.8 GO:1902560 GMP reductase complex(GO:1902560)
0.1 10.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.1 GO:0097413 Lewy body(GO:0097413)
0.1 4.7 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 26.2 GO:0031965 nuclear membrane(GO:0031965)
0.1 2.0 GO:0008305 integrin complex(GO:0008305)
0.1 5.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 6.5 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.1 1.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 1.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 32.3 GO:0016607 nuclear speck(GO:0016607)
0.1 2.5 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.1 2.0 GO:0032420 stereocilium(GO:0032420)
0.1 1.1 GO:0033268 node of Ranvier(GO:0033268)
0.1 1.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 3.9 GO:0005811 lipid particle(GO:0005811)
0.1 0.7 GO:0071141 SMAD protein complex(GO:0071141)
0.1 1.2 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 16.1 GO:0000790 nuclear chromatin(GO:0000790)
0.1 1.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.4 GO:0035869 ciliary transition zone(GO:0035869)
0.1 2.0 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.4 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 0.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.6 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.6 GO:0005771 multivesicular body(GO:0005771)
0.1 2.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 2.4 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 1.0 GO:0031105 septin complex(GO:0031105)
0.0 4.9 GO:0031514 motile cilium(GO:0031514)
0.0 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.8 GO:0000502 proteasome complex(GO:0000502)
0.0 3.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 13.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.8 GO:0016234 inclusion body(GO:0016234)
0.0 2.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.6 GO:0005902 microvillus(GO:0005902)
0.0 0.9 GO:0001726 ruffle(GO:0001726)
0.0 2.0 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.7 GO:0030027 lamellipodium(GO:0030027)
0.0 1.8 GO:0070161 anchoring junction(GO:0070161)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 47.9 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.6 GO:0031093 platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
4.6 23.0 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
4.3 12.8 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
4.0 24.3 GO:1990254 keratin filament binding(GO:1990254)
3.7 18.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
3.4 10.3 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
3.2 12.9 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
3.2 15.9 GO:0008420 CTD phosphatase activity(GO:0008420)
3.0 12.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
2.7 8.2 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
2.6 13.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
2.5 10.0 GO:0005046 KDEL sequence binding(GO:0005046)
2.2 8.8 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
2.2 15.2 GO:0004849 uridine kinase activity(GO:0004849)
2.2 15.2 GO:0048408 epidermal growth factor binding(GO:0048408)
2.1 6.3 GO:0032427 GBD domain binding(GO:0032427)
2.1 10.4 GO:0061665 SUMO ligase activity(GO:0061665)
2.1 6.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
2.0 8.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
2.0 6.0 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
2.0 9.9 GO:0070644 vitamin D response element binding(GO:0070644)
1.9 5.7 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
1.7 10.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.5 4.5 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
1.5 5.9 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
1.4 4.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
1.4 24.4 GO:0017154 semaphorin receptor activity(GO:0017154)
1.4 20.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
1.3 13.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
1.3 7.8 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
1.2 7.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.2 12.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.2 6.0 GO:1990460 leptin receptor binding(GO:1990460)
1.2 4.6 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
1.1 15.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.1 5.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
1.1 3.2 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
1.1 4.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
1.1 4.3 GO:0038025 glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
1.1 14.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.0 3.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.0 3.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
1.0 6.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.0 3.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
1.0 24.8 GO:0004859 phospholipase inhibitor activity(GO:0004859)
1.0 17.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.9 7.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.9 2.8 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.9 3.7 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.9 4.6 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.9 5.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.9 3.5 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.8 5.0 GO:0043237 laminin-1 binding(GO:0043237)
0.8 5.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.8 3.3 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.8 15.6 GO:0044548 S100 protein binding(GO:0044548)
0.8 4.9 GO:0098821 BMP receptor activity(GO:0098821)
0.8 6.5 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.8 7.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.8 10.4 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.8 6.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.8 4.7 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.8 3.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.8 6.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.8 7.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.7 16.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.7 2.1 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.7 13.7 GO:0043495 protein anchor(GO:0043495)
0.7 7.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.7 2.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.7 3.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.7 3.3 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.7 3.3 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.6 6.3 GO:0045159 myosin II binding(GO:0045159)
0.6 23.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.6 5.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.6 5.5 GO:1901612 cardiolipin binding(GO:1901612)
0.6 1.8 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.6 9.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.6 3.5 GO:0050692 DBD domain binding(GO:0050692)
0.6 4.7 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.6 10.6 GO:0097602 cullin family protein binding(GO:0097602)
0.6 5.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.5 6.0 GO:0051525 NFAT protein binding(GO:0051525)
0.5 1.6 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.5 2.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.5 5.6 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.5 9.1 GO:0008143 poly(A) binding(GO:0008143)
0.5 13.1 GO:0031489 myosin V binding(GO:0031489)
0.5 6.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.5 3.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.5 8.2 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.5 1.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.5 5.2 GO:0030274 LIM domain binding(GO:0030274)
0.5 2.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.5 2.8 GO:0004882 androgen receptor activity(GO:0004882)
0.5 9.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.4 4.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.4 5.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.4 1.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 12.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.4 2.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.4 1.3 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.4 6.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 1.7 GO:0004461 lactose synthase activity(GO:0004461)
0.4 1.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.4 13.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.4 11.5 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.4 5.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.4 0.8 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.4 3.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.4 2.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.4 13.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.4 15.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 5.2 GO:0035497 cAMP response element binding(GO:0035497)
0.4 1.8 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.4 3.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.4 4.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 5.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.4 10.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.3 2.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 4.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 15.0 GO:0050699 WW domain binding(GO:0050699)
0.3 6.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.3 1.7 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.3 1.0 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 2.9 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.3 31.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3 5.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 2.5 GO:0043559 insulin binding(GO:0043559)
0.3 4.0 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.3 4.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 8.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3 3.6 GO:0034452 dynactin binding(GO:0034452)
0.3 8.8 GO:0070064 proline-rich region binding(GO:0070064)
0.3 1.8 GO:0019238 cyclohydrolase activity(GO:0019238)
0.3 12.7 GO:0005158 insulin receptor binding(GO:0005158)
0.3 4.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.3 10.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.3 12.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.3 1.7 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.3 17.1 GO:0019003 GDP binding(GO:0019003)
0.3 25.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 6.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.3 2.4 GO:0004969 histamine receptor activity(GO:0004969)
0.3 4.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 4.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 7.0 GO:0071949 FAD binding(GO:0071949)
0.2 1.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.2 3.9 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.2 4.2 GO:0071837 HMG box domain binding(GO:0071837)
0.2 3.2 GO:0070700 BMP receptor binding(GO:0070700)
0.2 0.7 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.2 22.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.2 0.9 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2 2.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 2.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 3.4 GO:0048185 activin binding(GO:0048185)
0.2 7.6 GO:0019956 chemokine binding(GO:0019956)
0.2 0.6 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 2.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 2.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 4.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 8.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 3.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 1.0 GO:0017166 vinculin binding(GO:0017166)
0.2 2.6 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.2 2.8 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.2 11.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 1.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.2 3.6 GO:0005537 mannose binding(GO:0005537)
0.2 2.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 7.1 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.2 1.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 7.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 1.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 2.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 1.7 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 0.9 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 6.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 3.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 3.2 GO:0002039 p53 binding(GO:0002039)
0.2 2.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 1.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 3.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 17.3 GO:0035591 signaling adaptor activity(GO:0035591)
0.2 3.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.8 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 3.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.9 GO:0004871 signal transducer activity(GO:0004871)
0.1 6.1 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 2.7 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 41.8 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 3.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 20.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 7.4 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.1 3.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 6.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.2 GO:0035198 miRNA binding(GO:0035198)
0.1 2.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 5.3 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 24.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 3.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.8 GO:0004697 protein kinase C activity(GO:0004697)
0.1 2.1 GO:0005112 Notch binding(GO:0005112)
0.1 2.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 4.5 GO:0043621 protein self-association(GO:0043621)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.3 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.1 1.5 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 2.0 GO:0030515 snoRNA binding(GO:0030515)
0.1 1.9 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 1.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 18.4 GO:0003924 GTPase activity(GO:0003924)
0.1 1.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 1.8 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989)
0.1 3.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 13.6 GO:0008201 heparin binding(GO:0008201)
0.1 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.1 GO:0005522 profilin binding(GO:0005522)
0.1 1.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 3.0 GO:0008289 lipid binding(GO:0008289)
0.1 6.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.0 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 2.0 GO:0005123 death receptor binding(GO:0005123)
0.1 1.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 2.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 8.3 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.4 GO:0008483 transaminase activity(GO:0008483)
0.1 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 6.9 GO:0005178 integrin binding(GO:0005178)
0.1 1.9 GO:0000146 microfilament motor activity(GO:0000146)
0.1 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 8.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 5.1 GO:0005525 GTP binding(GO:0005525)
0.0 3.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.9 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 3.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 7.1 GO:0005125 cytokine activity(GO:0005125)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.6 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.5 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.6 GO:0016791 phosphatase activity(GO:0016791)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 3.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 2.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.7 GO:0003682 chromatin binding(GO:0003682)
0.0 1.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.0 GO:0019902 phosphatase binding(GO:0019902)
0.0 1.7 GO:0016874 ligase activity(GO:0016874)
0.0 2.9 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 50.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.8 24.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.8 17.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.6 38.3 PID INSULIN PATHWAY Insulin Pathway
0.6 5.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.6 30.4 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.6 24.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.6 44.5 PID CDC42 PATHWAY CDC42 signaling events
0.6 34.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.6 22.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.5 13.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 7.3 PID IL5 PATHWAY IL5-mediated signaling events
0.5 7.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.4 5.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.4 22.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.4 25.6 PID AURORA B PATHWAY Aurora B signaling
0.4 20.3 PID BMP PATHWAY BMP receptor signaling
0.4 26.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 3.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.3 6.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.3 12.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.3 10.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 56.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 11.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 23.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.3 9.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.3 3.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 12.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 20.2 PID LKB1 PATHWAY LKB1 signaling events
0.3 7.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 6.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 5.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 6.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 8.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 3.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 2.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 2.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.2 6.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 3.1 PID IFNG PATHWAY IFN-gamma pathway
0.2 6.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 0.5 PID IGF1 PATHWAY IGF1 pathway
0.2 11.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 1.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 9.0 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 5.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 11.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 8.3 PID E2F PATHWAY E2F transcription factor network
0.1 1.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 7.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 26.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 4.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 4.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 4.5 PID PLK1 PATHWAY PLK1 signaling events
0.1 3.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 7.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 4.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 1.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 3.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 2.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 3.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.4 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.1 PID ARF 3PATHWAY Arf1 pathway
0.1 2.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 8.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 3.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.8 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.4 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 38.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
1.2 24.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
1.0 32.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.9 22.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.9 24.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.9 15.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.8 33.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.8 7.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.8 13.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.8 23.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.7 13.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.7 7.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.6 14.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.6 22.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.6 3.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.6 16.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.6 0.6 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.5 13.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.5 11.0 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.5 9.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.5 16.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.5 15.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.5 4.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.5 5.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.5 10.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.4 10.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.4 9.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 13.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.4 6.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.4 4.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3 6.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 3.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 7.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.3 14.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.3 6.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3 30.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3 12.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.3 6.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 4.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 8.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 9.1 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.3 9.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.3 1.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 5.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.3 0.8 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.2 8.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 1.0 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.2 2.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 6.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.2 22.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 9.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.2 6.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.2 3.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 4.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 3.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 4.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 2.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 7.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 1.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 4.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 7.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 5.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 3.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 3.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 11.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 3.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 6.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 11.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 20.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 6.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 3.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 11.3 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.1 1.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 11.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 2.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 5.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 1.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 4.6 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 4.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 3.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 1.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 3.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 2.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 2.0 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 0.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen