GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
chr2_-_151344172 Show fit | 22.56 |
ENST00000375734.2
ENST00000263895.4 ENST00000454202.1 |
Rho family GTPase 3 |
|
chrX_+_64887512 Show fit | 22.04 |
ENST00000360270.5
|
moesin |
|
chr12_-_109125285 Show fit | 19.76 |
ENST00000552871.1
ENST00000261401.3 |
coronin, actin binding protein, 1C |
|
chr3_-_120170052 Show fit | 19.45 |
ENST00000295633.3
|
follistatin-like 1 |
|
chr9_+_112810878 Show fit | 17.25 |
ENST00000434623.2
ENST00000374525.1 |
A kinase (PRKA) anchor protein 2 |
|
chr12_-_15942309 Show fit | 16.75 |
ENST00000544064.1
ENST00000543523.1 ENST00000536793.1 |
epidermal growth factor receptor pathway substrate 8 |
|
chr17_-_62658186 Show fit | 16.30 |
ENST00000262435.9
|
SMAD specific E3 ubiquitin protein ligase 2 |
|
chr6_-_122792919 Show fit | 16.01 |
ENST00000339697.4
|
serine incorporator 1 |
|
chr5_+_17217669 Show fit | 15.67 |
ENST00000322611.3
|
brain abundant, membrane attached signal protein 1 |
|
chr7_-_94285511 Show fit | 15.62 |
ENST00000265735.7
|
sarcoglycan, epsilon |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 39.2 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
1.6 | 27.0 | GO:0070831 | basement membrane assembly(GO:0070831) |
1.2 | 23.6 | GO:0051764 | actin crosslink formation(GO:0051764) |
3.7 | 22.0 | GO:0022614 | membrane to membrane docking(GO:0022614) |
2.0 | 20.0 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
0.4 | 19.6 | GO:0035329 | hippo signaling(GO:0035329) |
4.3 | 17.2 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
4.2 | 16.8 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
2.0 | 16.0 | GO:0015825 | L-serine transport(GO:0015825) |
3.1 | 15.7 | GO:2001074 | regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 40.3 | GO:0043197 | dendritic spine(GO:0043197) |
0.2 | 30.2 | GO:0031902 | late endosome membrane(GO:0031902) |
0.1 | 29.6 | GO:0005925 | focal adhesion(GO:0005925) |
0.1 | 27.9 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
1.0 | 22.0 | GO:0001931 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.2 | 20.8 | GO:0032432 | actin filament bundle(GO:0032432) |
0.6 | 19.7 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.4 | 19.6 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.1 | 18.9 | GO:0055037 | recycling endosome(GO:0055037) |
0.9 | 17.9 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 48.7 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.6 | 40.7 | GO:0019003 | GDP binding(GO:0019003) |
0.2 | 33.5 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.4 | 29.4 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.1 | 23.2 | GO:0008201 | heparin binding(GO:0008201) |
0.1 | 22.7 | GO:0003924 | GTPase activity(GO:0003924) |
0.1 | 22.2 | GO:0051015 | actin filament binding(GO:0051015) |
0.8 | 20.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.6 | 17.0 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
2.4 | 16.5 | GO:0050815 | phosphoserine binding(GO:0050815) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 38.0 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
0.5 | 28.8 | PID RHOA PATHWAY | RhoA signaling pathway |
0.6 | 20.4 | PID S1P S1P2 PATHWAY | S1P2 pathway |
0.3 | 19.7 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
0.5 | 19.2 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
0.4 | 19.0 | PID EPHB FWD PATHWAY | EPHB forward signaling |
0.3 | 17.4 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
0.3 | 16.5 | PID ATR PATHWAY | ATR signaling pathway |
0.1 | 14.3 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
0.4 | 14.1 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 33.9 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
0.7 | 32.9 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
1.0 | 23.1 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.2 | 17.6 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.8 | 16.9 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
1.4 | 14.9 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.5 | 13.8 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
0.4 | 13.3 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
0.5 | 12.9 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
0.9 | 12.8 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |