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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ACCACAG

Z-value: 0.28

Motif logo

logo of

miRNA associated with seed ACCACAG

NamemiRBASE accession
hsa-miR-140-3p.2
MIMAT0004597

Activity profile of ACCACAG motif

Sorted Z-values of ACCACAG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_107811162 3.03 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr20_+_10199468 2.42 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr4_+_166300084 1.74 ENST00000402744.4
CPE
carboxypeptidase E
chr11_-_117747607 1.69 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chr11_+_63448955 1.68 ENST00000377819.5
ENST00000339997.4
ENST00000540798.1
ENST00000545432.1
ENST00000543552.1
ENST00000537981.1
RTN3
reticulon 3
chr8_+_136469684 1.40 ENST00000355849.5
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr14_+_29234870 1.31 ENST00000382535.3
FOXG1
forkhead box G1
chr13_+_58206655 1.28 ENST00000377918.3
PCDH17
protocadherin 17
chr17_+_47865917 1.23 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
KAT7
K(lysine) acetyltransferase 7
chr1_-_182361327 1.20 ENST00000331872.6
ENST00000311223.5
GLUL
glutamate-ammonia ligase
chrX_+_23352133 1.05 ENST00000379361.4
PTCHD1
patched domain containing 1
chr1_-_230561475 1.02 ENST00000391860.1
PGBD5
piggyBac transposable element derived 5
chr11_-_78052923 0.94 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr19_+_19322758 0.93 ENST00000252575.6
NCAN
neurocan
chr3_+_158991025 0.92 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr15_-_83316254 0.92 ENST00000567678.1
ENST00000450751.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr3_+_49591881 0.90 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr5_-_111093406 0.89 ENST00000379671.3
NREP
neuronal regeneration related protein
chr4_-_153457197 0.86 ENST00000281708.4
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr3_-_9291063 0.84 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr11_-_117186946 0.83 ENST00000313005.6
ENST00000528053.1
BACE1
beta-site APP-cleaving enzyme 1
chr12_-_49393092 0.82 ENST00000421952.2
DDN
dendrin
chr11_-_66115032 0.81 ENST00000311181.4
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr7_+_94139105 0.75 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr10_+_60028818 0.72 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr20_+_36149602 0.70 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr3_+_159557637 0.67 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr1_+_244214577 0.65 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chrX_-_47479246 0.60 ENST00000295987.7
ENST00000340666.4
SYN1
synapsin I
chr12_-_117628333 0.59 ENST00000427718.2
FBXO21
F-box protein 21
chr15_+_41851211 0.58 ENST00000263798.3
TYRO3
TYRO3 protein tyrosine kinase
chr1_-_154531095 0.53 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr3_+_238273 0.52 ENST00000256509.2
CHL1
cell adhesion molecule L1-like
chr6_+_135502466 0.51 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr11_+_58939965 0.51 ENST00000227451.3
DTX4
deltex homolog 4 (Drosophila)
chr8_-_82024290 0.50 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr15_-_77363513 0.50 ENST00000267970.4
TSPAN3
tetraspanin 3
chr16_+_14927538 0.50 ENST00000287667.7
NOMO1
NODAL modulator 1
chr22_-_22221900 0.50 ENST00000215832.6
ENST00000398822.3
MAPK1
mitogen-activated protein kinase 1
chr1_+_155290677 0.50 ENST00000368354.3
ENST00000368352.5
RUSC1
RUN and SH3 domain containing 1
chr4_+_6784401 0.48 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr2_-_200322723 0.46 ENST00000417098.1
SATB2
SATB homeobox 2
chr2_-_206950781 0.46 ENST00000403263.1
INO80D
INO80 complex subunit D
chr13_-_53422640 0.44 ENST00000338862.4
ENST00000377942.3
PCDH8
protocadherin 8
chr2_-_240322643 0.44 ENST00000345617.3
HDAC4
histone deacetylase 4
chr17_+_53342311 0.41 ENST00000226067.5
HLF
hepatic leukemia factor
chr17_-_36956155 0.40 ENST00000269554.3
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr9_+_82186872 0.40 ENST00000376544.3
ENST00000376520.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr13_+_22245522 0.39 ENST00000382353.5
FGF9
fibroblast growth factor 9
chr10_+_92980517 0.38 ENST00000336126.5
PCGF5
polycomb group ring finger 5
chr3_-_114790179 0.37 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr5_+_61602055 0.37 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr12_+_74931551 0.37 ENST00000519948.2
ATXN7L3B
ataxin 7-like 3B
chr2_-_235405679 0.36 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr13_-_30169807 0.35 ENST00000380752.5
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr2_-_166060571 0.35 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr14_+_65171099 0.35 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr22_+_35653445 0.35 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMGXB4
HMG box domain containing 4
chr2_+_173940442 0.34 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr10_+_11206925 0.33 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr19_-_47616992 0.33 ENST00000253048.5
ZC3H4
zinc finger CCCH-type containing 4
chrX_+_56590002 0.32 ENST00000338222.5
UBQLN2
ubiquilin 2
chr3_-_57678772 0.32 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr9_-_33264676 0.32 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr20_-_48099182 0.31 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr3_-_192445289 0.31 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12
fibroblast growth factor 12
chr2_-_222436988 0.31 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPHA4
EPH receptor A4
chr22_-_36236265 0.31 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr18_+_21693306 0.30 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr20_+_1875110 0.30 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr5_+_139493665 0.29 ENST00000331327.3
PURA
purine-rich element binding protein A
chr7_+_65338230 0.29 ENST00000360768.3
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr2_+_113033164 0.29 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr5_+_10353780 0.28 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
MARCH6
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chr2_-_175113301 0.27 ENST00000344357.5
ENST00000284719.3
OLA1
Obg-like ATPase 1
chr17_-_27893990 0.27 ENST00000307201.4
ABHD15
abhydrolase domain containing 15
chr4_-_1242764 0.26 ENST00000514210.1
ENST00000382952.3
ENST00000290921.6
CTBP1
C-terminal binding protein 1
chr5_-_19988339 0.26 ENST00000382275.1
CDH18
cadherin 18, type 2
chr1_+_180601139 0.26 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr3_-_48700310 0.26 ENST00000164024.4
ENST00000544264.1
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3
chr17_-_27278304 0.26 ENST00000577226.1
PHF12
PHD finger protein 12
chr5_+_154092396 0.25 ENST00000336314.4
LARP1
La ribonucleoprotein domain family, member 1
chr9_+_2015335 0.25 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_+_110719032 0.25 ENST00000395494.2
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr11_+_119076745 0.25 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr1_+_91966384 0.25 ENST00000430031.2
ENST00000234626.6
CDC7
cell division cycle 7
chr15_-_50558223 0.25 ENST00000267845.3
HDC
histidine decarboxylase
chr1_-_40157345 0.24 ENST00000372844.3
HPCAL4
hippocalcin like 4
chr1_+_161123536 0.24 ENST00000368003.5
UFC1
ubiquitin-fold modifier conjugating enzyme 1
chrX_-_124097620 0.23 ENST00000371130.3
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr5_-_132299313 0.23 ENST00000265343.5
AFF4
AF4/FMR2 family, member 4
chr2_-_166930131 0.23 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr16_+_16326352 0.23 ENST00000399336.4
ENST00000263012.6
ENST00000538468.1
NOMO3
NODAL modulator 3
chr3_-_186080012 0.21 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr10_+_76871454 0.21 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr8_+_61429416 0.21 ENST00000262646.7
ENST00000531289.1
RAB2A
RAB2A, member RAS oncogene family
chr8_-_93115445 0.20 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_+_9413410 0.20 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr6_-_79944336 0.20 ENST00000344726.5
ENST00000275036.7
HMGN3
high mobility group nucleosomal binding domain 3
chr1_+_62902308 0.19 ENST00000339950.4
USP1
ubiquitin specific peptidase 1
chr3_-_171178157 0.18 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TNIK
TRAF2 and NCK interacting kinase
chr12_+_12938541 0.17 ENST00000356591.4
APOLD1
apolipoprotein L domain containing 1
chr7_+_155250824 0.17 ENST00000297375.4
EN2
engrailed homeobox 2
chr11_+_34073195 0.17 ENST00000341394.4
CAPRIN1
cell cycle associated protein 1
chr11_-_67980744 0.16 ENST00000401547.2
ENST00000453170.1
ENST00000304363.4
SUV420H1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr12_+_57943781 0.16 ENST00000455537.2
ENST00000286452.5
KIF5A
kinesin family member 5A
chr9_-_74980113 0.16 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr18_+_13218769 0.16 ENST00000399848.3
ENST00000361205.4
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr12_-_56583332 0.16 ENST00000347471.4
ENST00000267064.4
ENST00000394023.3
SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr5_+_157170703 0.16 ENST00000286307.5
LSM11
LSM11, U7 small nuclear RNA associated
chr8_-_101965146 0.15 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr6_-_62996066 0.15 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr8_+_61591337 0.15 ENST00000423902.2
CHD7
chromodomain helicase DNA binding protein 7
chr1_-_57045228 0.15 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr17_-_62502639 0.15 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr22_+_32439019 0.14 ENST00000266088.4
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr3_+_141205852 0.13 ENST00000286364.3
ENST00000452898.1
RASA2
RAS p21 protein activator 2
chr11_+_925824 0.13 ENST00000525796.1
ENST00000534328.1
ENST00000448903.2
ENST00000332231.5
AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr9_-_23821273 0.12 ENST00000380110.4
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr9_-_100395756 0.11 ENST00000341170.4
ENST00000354801.2
TSTD2
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr17_-_6459768 0.10 ENST00000421306.3
PITPNM3
PITPNM family member 3
chr2_+_27193480 0.10 ENST00000233121.2
ENST00000405074.3
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr1_-_115053781 0.09 ENST00000358465.2
ENST00000369543.2
TRIM33
tripartite motif containing 33
chr6_+_37400974 0.09 ENST00000455891.1
ENST00000373451.4
CMTR1
cap methyltransferase 1
chr18_+_52495426 0.09 ENST00000262094.5
RAB27B
RAB27B, member RAS oncogene family
chrX_-_153363188 0.09 ENST00000303391.6
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chr7_+_138916231 0.09 ENST00000473989.3
ENST00000288561.8
UBN2
ubinuclein 2
chrX_+_100474711 0.08 ENST00000402866.1
DRP2
dystrophin related protein 2
chr14_-_77279153 0.08 ENST00000251089.2
ANGEL1
angel homolog 1 (Drosophila)
chr18_+_9913977 0.08 ENST00000400000.2
ENST00000340541.4
VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr5_-_175964366 0.08 ENST00000274811.4
RNF44
ring finger protein 44
chr3_-_9834375 0.07 ENST00000343450.2
ENST00000301964.2
TADA3
transcriptional adaptor 3
chr3_-_160823040 0.06 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr17_+_67410832 0.06 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr17_+_1958388 0.06 ENST00000399849.3
HIC1
hypermethylated in cancer 1
chr19_+_47421933 0.06 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr17_-_79885576 0.06 ENST00000574686.1
ENST00000357736.4
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr3_+_140660634 0.06 ENST00000446041.2
ENST00000507429.1
ENST00000324194.6
SLC25A36
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr10_-_120514720 0.06 ENST00000369151.3
ENST00000340214.4
CACUL1
CDK2-associated, cullin domain 1
chr17_+_45727204 0.05 ENST00000290158.4
KPNB1
karyopherin (importin) beta 1
chr6_-_17706618 0.05 ENST00000262077.2
ENST00000537253.1
NUP153
nucleoporin 153kDa
chr2_-_38604398 0.05 ENST00000443098.1
ENST00000449130.1
ENST00000378954.4
ENST00000539122.1
ENST00000419554.2
ENST00000451483.1
ENST00000406122.1
ATL2
atlastin GTPase 2
chr5_+_141303373 0.05 ENST00000432126.2
ENST00000194118.4
KIAA0141
KIAA0141
chr6_+_44355257 0.05 ENST00000371477.3
CDC5L
cell division cycle 5-like
chr9_+_131709966 0.05 ENST00000372577.2
NUP188
nucleoporin 188kDa
chr12_-_54582655 0.04 ENST00000504338.1
ENST00000514685.1
ENST00000504797.1
ENST00000513838.1
ENST00000505128.1
ENST00000337581.3
ENST00000503306.1
ENST00000243112.5
ENST00000514196.1
ENST00000506169.1
ENST00000507904.1
ENST00000508394.2
SMUG1
single-strand-selective monofunctional uracil-DNA glycosylase 1
chr1_+_35734562 0.04 ENST00000314607.6
ENST00000373297.2
ZMYM4
zinc finger, MYM-type 4
chr1_+_147013182 0.04 ENST00000234739.3
BCL9
B-cell CLL/lymphoma 9
chr11_+_111473108 0.03 ENST00000304987.3
SIK2
salt-inducible kinase 2
chr13_-_27334879 0.03 ENST00000405846.3
GPR12
G protein-coupled receptor 12
chr19_-_44100275 0.03 ENST00000422989.1
ENST00000598324.1
IRGQ
immunity-related GTPase family, Q
chr3_+_110790590 0.03 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr15_+_89631381 0.03 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr2_+_135676381 0.03 ENST00000537343.1
ENST00000295238.6
ENST00000264157.5
CCNT2
cyclin T2
chr15_+_89164520 0.03 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr11_+_129939779 0.03 ENST00000533195.1
ENST00000533713.1
ENST00000528499.1
ENST00000539648.1
ENST00000263574.5
APLP2
amyloid beta (A4) precursor-like protein 2
chr2_+_61108650 0.02 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr3_-_49823941 0.02 ENST00000321599.4
ENST00000395238.1
ENST00000468463.1
ENST00000460540.1
IP6K1
inositol hexakisphosphate kinase 1
chr19_-_14117074 0.02 ENST00000588885.1
ENST00000254325.4
RFX1
regulatory factor X, 1 (influences HLA class II expression)
chr11_+_33278811 0.02 ENST00000303296.4
ENST00000379016.3
HIPK3
homeodomain interacting protein kinase 3
chr18_-_44497308 0.02 ENST00000585916.1
ENST00000324794.7
ENST00000545673.1
PIAS2
protein inhibitor of activated STAT, 2
chr13_-_99630233 0.01 ENST00000376460.1
ENST00000442173.1
DOCK9
dedicator of cytokinesis 9
chr17_+_30264014 0.01 ENST00000322652.5
ENST00000580398.1
SUZ12
SUZ12 polycomb repressive complex 2 subunit
chr14_-_34420259 0.01 ENST00000250457.3
ENST00000547327.2
EGLN3
egl-9 family hypoxia-inducible factor 3
chr8_-_116681221 0.01 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr15_-_37390482 0.01 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr5_+_156607829 0.01 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr17_+_54911444 0.01 ENST00000284061.3
ENST00000572810.1
DGKE
diacylglycerol kinase, epsilon 64kDa
chr2_-_70780770 0.00 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chr9_-_98279241 0.00 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
PTCH1
patched 1
chr2_-_232329186 0.00 ENST00000322723.4
NCL
nucleolin
chr10_-_98273668 0.00 ENST00000357947.3
TLL2
tolloid-like 2
chr12_+_67663056 0.00 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ACCACAG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 1.7 GO:0030070 insulin processing(GO:0030070)
0.3 1.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.3 1.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 1.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 0.9 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 0.5 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 0.5 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.3 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.8 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.1 0.4 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.3 GO:1901355 response to rapamycin(GO:1901355)
0.1 0.3 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.1 0.2 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.3 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.1 0.3 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.7 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.3 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.1 1.1 GO:0021794 thalamus development(GO:0021794)
0.1 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.9 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.2 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 2.9 GO:0090102 cochlea development(GO:0090102)
0.0 0.5 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.3 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.4 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.3 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.3 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114) negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.7 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 1.7 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.5 GO:0035640 exploration behavior(GO:0035640)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.8 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.0 GO:1990637 response to prolactin(GO:1990637)
0.0 0.0 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.9 GO:0035418 protein localization to synapse(GO:0035418)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.2 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.2 GO:0097386 glial cell projection(GO:0097386)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0071204 U7 snRNP(GO:0005683) histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.9 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 1.2 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0032184 SUMO polymer binding(GO:0032184)
0.3 1.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 0.8 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 2.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.3 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.8 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 2.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.9 PID AURORA A PATHWAY Aurora A signaling
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 1.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.8 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription