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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AGGUAGU

Z-value: 0.41

Motif logo

miRNA associated with seed AGGUAGU

NamemiRBASE accession
MIMAT0000226
MIMAT0001080

Activity profile of AGGUAGU motif

Sorted Z-values of AGGUAGU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_94023873 5.70 ENST00000297268.6
collagen, type I, alpha 2
chr2_+_189839046 4.84 ENST00000304636.3
ENST00000317840.5
collagen, type III, alpha 1
chr12_+_66217911 4.10 ENST00000403681.2
high mobility group AT-hook 2
chr5_-_131132614 3.48 ENST00000307968.7
ENST00000307954.8
folliculin interacting protein 1
chr1_-_204380919 3.06 ENST00000367188.4
protein phosphatase 1, regulatory subunit 15B
chr3_-_28390581 3.01 ENST00000479665.1
5-azacytidine induced 2
chr17_-_46682321 2.78 ENST00000225648.3
ENST00000484302.2
homeobox B6
chr3_+_158991025 2.65 ENST00000337808.6
IQCJ-SCHIP1 readthrough
chr17_-_48278983 2.48 ENST00000225964.5
collagen, type I, alpha 1
chr3_+_159557637 2.40 ENST00000445224.2
schwannomin interacting protein 1
chr3_+_110790590 2.37 ENST00000485303.1
poliovirus receptor-related 3
chr1_-_115259337 2.27 ENST00000369535.4
neuroblastoma RAS viral (v-ras) oncogene homolog
chr9_-_16870704 2.25 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
basonuclin 2
chr3_+_61547585 2.02 ENST00000295874.10
ENST00000474889.1
protein tyrosine phosphatase, receptor type, G
chr17_-_46688334 2.00 ENST00000239165.7
homeobox B7
chr7_-_23510086 1.98 ENST00000258729.3
insulin-like growth factor 2 mRNA binding protein 3
chr2_+_204192942 1.97 ENST00000295851.5
ENST00000261017.5
abl-interactor 2
chr5_+_178286925 1.91 ENST00000322434.3
zinc finger protein 354B
chr18_+_19749386 1.89 ENST00000269216.3
GATA binding protein 6
chr2_-_39664405 1.82 ENST00000341681.5
ENST00000263881.3
mitogen-activated protein kinase kinase kinase kinase 3
chr2_+_242641442 1.81 ENST00000313552.6
ENST00000406941.1
inhibitor of growth family, member 5
chrX_-_132549506 1.79 ENST00000370828.3
glypican 4
chr5_-_37371278 1.78 ENST00000231498.3
nucleoporin 155kDa
chr7_+_94285637 1.78 ENST00000482108.1
ENST00000488574.1
paternally expressed 10
chrX_+_134166333 1.54 ENST00000257013.7
family with sequence similarity 127, member A
chr8_-_82754427 1.52 ENST00000353788.4
ENST00000520618.1
ENST00000518183.1
ENST00000396330.2
ENST00000519119.1
ENST00000345957.4
sorting nexin 16
chr4_+_113066552 1.35 ENST00000309733.5
chromosome 4 open reading frame 32
chr1_+_164528866 1.35 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr14_-_57735528 1.28 ENST00000340918.7
ENST00000413566.2
exocyst complex component 5
chr12_-_69326940 1.26 ENST00000549781.1
ENST00000548262.1
ENST00000551568.1
ENST00000548954.1
carboxypeptidase M
chr20_+_306221 1.24 ENST00000342665.2
SRY (sex determining region Y)-box 12
chrX_+_95939711 1.24 ENST00000373049.4
ENST00000324765.8
diaphanous-related formin 2
chr3_+_14989076 1.15 ENST00000413118.1
ENST00000425241.1
nuclear receptor subfamily 2, group C, member 2
chrX_-_134186144 1.15 ENST00000370775.2
family with sequence similarity 127, member B
chr20_+_49348081 1.14 ENST00000371610.2
par-6 family cell polarity regulator beta
chr1_+_193091080 1.13 ENST00000367435.3
cell division cycle 73
chr15_+_45879321 1.11 ENST00000220531.3
ENST00000567461.1
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr1_+_18958008 1.07 ENST00000420770.2
ENST00000400661.3
paired box 7
chr9_+_99212403 1.05 ENST00000375251.3
ENST00000375249.4
hyaluronan binding protein 4
chr12_-_25102252 1.03 ENST00000261192.7
branched chain amino-acid transaminase 1, cytosolic
chr8_+_22102626 1.01 ENST00000519237.1
ENST00000397802.4
polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
chr11_-_796197 0.96 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr1_+_26737253 0.92 ENST00000326279.6
lin-28 homolog A (C. elegans)
chr11_-_110167352 0.91 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
radixin
chr9_+_132934835 0.86 ENST00000372398.3
neuronal calcium sensor 1
chr18_+_6834472 0.85 ENST00000581099.1
ENST00000419673.2
ENST00000531294.1
Rho GTPase activating protein 28
chr5_+_38846101 0.81 ENST00000274276.3
oncostatin M receptor
chr2_+_109335929 0.80 ENST00000283195.6
RAN binding protein 2
chr8_+_37594130 0.77 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ER lipid raft associated 2
chr9_+_115983808 0.72 ENST00000374210.6
ENST00000374212.4
solute carrier family 31 (copper transporter), member 1
chr15_-_34502278 0.68 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
katanin p80 subunit B-like 1
chr6_+_34204642 0.66 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr12_-_93323013 0.65 ENST00000322349.8
early endosome antigen 1
chr15_+_52043758 0.65 ENST00000249700.4
ENST00000539962.2
tropomodulin 2 (neuronal)
chr2_+_170590321 0.64 ENST00000392647.2
kelch-like family member 23
chr5_-_35230771 0.62 ENST00000342362.5
prolactin receptor
chr6_-_35464727 0.61 ENST00000402886.3
TEA domain family member 3
chr2_+_5832799 0.60 ENST00000322002.3
SRY (sex determining region Y)-box 11
chr2_-_128615681 0.57 ENST00000409955.1
ENST00000272645.4
polymerase (RNA) II (DNA directed) polypeptide D
chr9_-_127533519 0.57 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
nuclear receptor subfamily 6, group A, member 1
chr4_+_56212270 0.56 ENST00000264228.4
steroid 5 alpha-reductase 3
chr1_+_60280458 0.55 ENST00000455990.1
ENST00000371208.3
hook microtubule-tethering protein 1
chr14_-_81687197 0.54 ENST00000553612.1
general transcription factor IIA, 1, 19/37kDa
chr10_+_97803151 0.54 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
cyclin J
chr7_-_98741642 0.52 ENST00000361368.2
SMAD specific E3 ubiquitin protein ligase 1
chr7_-_27183263 0.50 ENST00000222726.3
homeobox A5
chr17_+_28705921 0.49 ENST00000225719.4
carboxypeptidase D
chrX_-_41782249 0.48 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr6_+_134274322 0.47 ENST00000367871.1
ENST00000237264.4
TBP-like 1
chr5_-_74326724 0.46 ENST00000322348.4
glucosaminyl (N-acetyl) transferase 4, core 2
chr4_+_55095264 0.45 ENST00000257290.5
platelet-derived growth factor receptor, alpha polypeptide
chr3_-_48229846 0.44 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
cell division cycle 25A
chr7_+_18535346 0.44 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
histone deacetylase 9
chr12_-_57400227 0.44 ENST00000300101.2
zinc finger and BTB domain containing 39
chr16_+_81348528 0.41 ENST00000568107.2
gigaxonin
chr1_-_207224307 0.41 ENST00000315927.4
YOD1 deubiquitinase
chr8_+_58907104 0.40 ENST00000361488.3
family with sequence similarity 110, member B
chr22_+_39898325 0.39 ENST00000325301.2
ENST00000404569.1
mitochondrial elongation factor 1
chr7_-_83824169 0.38 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_205601064 0.38 ENST00000357992.4
ENST00000289703.4
ELK4, ETS-domain protein (SRF accessory protein 1)
chr12_-_57472522 0.36 ENST00000379391.3
ENST00000300128.4
transmembrane protein 194A
chr19_+_531713 0.36 ENST00000215574.4
cell division cycle 34
chr5_-_131347306 0.36 ENST00000296869.4
ENST00000379249.3
ENST00000379272.2
ENST00000379264.2
acyl-CoA synthetase long-chain family member 6
chrX_+_48554986 0.35 ENST00000376687.3
ENST00000453214.2
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr11_+_111945011 0.34 ENST00000532163.1
ENST00000280352.9
ENST00000530104.1
ENST00000526879.1
ENST00000393047.3
ENST00000525785.1
chromosome 11 open reading frame 57
chr1_+_153232160 0.34 ENST00000368742.3
loricrin
chr7_-_120498357 0.34 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr3_+_50712672 0.31 ENST00000266037.9
dedicator of cytokinesis 3
chr8_-_110988070 0.29 ENST00000524391.1
potassium channel, subfamily V, member 1
chr19_+_14063278 0.29 ENST00000254337.6
DDB1 and CUL4 associated factor 15
chr9_-_79520989 0.28 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
prune homolog 2 (Drosophila)
chr3_-_53080047 0.27 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
Scm-like with four mbt domains 1
chrX_+_2746850 0.23 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
glycogenin 2
chr1_+_113615794 0.23 ENST00000361127.5
leucine-rich repeats and immunoglobulin-like domains 2
chr2_+_113239710 0.22 ENST00000233336.6
tubulin tyrosine ligase
chr19_-_47975417 0.22 ENST00000236877.6
solute carrier family 8 (sodium/calcium exchanger), member 2
chr21_+_47878757 0.21 ENST00000400274.1
ENST00000427143.2
ENST00000318711.7
ENST00000457905.3
ENST00000466639.1
ENST00000435722.3
ENST00000417564.2
DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr9_-_72287191 0.21 ENST00000265381.4
amyloid beta (A4) precursor protein-binding, family A, member 1
chr9_+_110045537 0.21 ENST00000358015.3
RAD23 homolog B (S. cerevisiae)
chr15_-_50411412 0.21 ENST00000284509.6
ATPase, class I, type 8B, member 4
chr22_-_22221900 0.21 ENST00000215832.6
ENST00000398822.3
mitogen-activated protein kinase 1
chr1_-_92351769 0.21 ENST00000212355.4
transforming growth factor, beta receptor III
chr16_-_4166186 0.21 ENST00000294016.3
adenylate cyclase 9
chr8_+_121137333 0.20 ENST00000309791.4
ENST00000297848.3
ENST00000247781.3
collagen, type XIV, alpha 1
chr6_-_86352642 0.20 ENST00000355238.6
synaptotagmin binding, cytoplasmic RNA interacting protein
chr6_+_24403144 0.19 ENST00000274747.7
ENST00000543597.1
ENST00000535061.1
ENST00000378353.1
ENST00000378386.3
ENST00000443868.2
MRS2 magnesium transporter
chr20_-_32700075 0.18 ENST00000374980.2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr12_-_29534074 0.17 ENST00000546839.1
ENST00000360150.4
ENST00000552155.1
ENST00000550353.1
ENST00000548441.1
ENST00000552132.1
ERGIC and golgi 2
chr15_+_66994561 0.17 ENST00000288840.5
SMAD family member 6
chr12_-_102874416 0.16 ENST00000392904.1
ENST00000337514.6
insulin-like growth factor 1 (somatomedin C)
chr17_+_8213590 0.16 ENST00000361926.3
Rho guanine nucleotide exchange factor (GEF) 15
chr4_+_106473768 0.16 ENST00000265154.2
ENST00000420470.2
Rho guanine nucleotide exchange factor (GEF) 38
chrX_+_49687216 0.15 ENST00000376088.3
chloride channel, voltage-sensitive 5
chrX_-_77150985 0.15 ENST00000358075.6
magnesium transporter 1
chr22_+_30279144 0.14 ENST00000401950.2
ENST00000333027.3
ENST00000445401.1
ENST00000323630.5
ENST00000351488.3
myotubularin related protein 3
chr18_-_24445729 0.13 ENST00000383168.4
aquaporin 4
chr6_+_133562472 0.12 ENST00000430974.2
ENST00000367895.5
ENST00000355167.3
ENST00000355286.6
eyes absent homolog 4 (Drosophila)
chr2_-_50574856 0.12 ENST00000342183.5
neurexin 1
chr21_+_30671189 0.12 ENST00000286800.3
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr16_-_67840442 0.11 ENST00000536251.1
ENST00000448631.2
ENST00000602677.1
ENST00000411657.2
ENST00000425512.2
ENST00000317506.3
RAN binding protein 10
chr6_-_7313381 0.11 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
signal sequence receptor, alpha
chr7_+_35840542 0.11 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
septin 7
chr17_-_61850894 0.11 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
coiled-coil domain containing 47
chr18_-_18691739 0.11 ENST00000399799.2
Rho-associated, coiled-coil containing protein kinase 1
chr12_+_123868320 0.10 ENST00000402868.3
ENST00000330479.4
SET domain containing (lysine methyltransferase) 8
chr21_-_39870339 0.10 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
v-ets avian erythroblastosis virus E26 oncogene homolog
chr7_-_27196267 0.10 ENST00000242159.3
homeobox A7
chr11_+_63870660 0.09 ENST00000246841.3
fibronectin leucine rich transmembrane protein 1
chr16_+_447209 0.08 ENST00000382940.4
ENST00000219479.2
NME/NM23 nucleoside diphosphate kinase 4
chr18_+_55711575 0.08 ENST00000356462.6
ENST00000400345.3
ENST00000589054.1
ENST00000256832.7
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr16_+_70332956 0.08 ENST00000288071.6
ENST00000393657.2
ENST00000355992.3
ENST00000567706.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
Uncharacterized protein
chr7_-_75368248 0.07 ENST00000434438.2
ENST00000336926.6
huntingtin interacting protein 1
chr2_+_60983361 0.07 ENST00000238714.3
poly(A) polymerase gamma
chr13_-_103053946 0.07 ENST00000376131.4
fibroblast growth factor 14
chr12_-_123450986 0.07 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr3_-_47823298 0.06 ENST00000254480.5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr8_+_59465728 0.05 ENST00000260130.4
ENST00000422546.2
ENST00000447182.2
ENST00000413219.2
ENST00000424270.2
ENST00000523483.1
ENST00000520168.1
syndecan binding protein (syntenin)
chr6_+_4890226 0.05 ENST00000343762.5
chromodomain protein, Y-like
chr14_-_34931458 0.05 ENST00000298130.4
serine palmitoyltransferase, small subunit A
chr7_-_27205136 0.05 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr11_-_132813566 0.05 ENST00000331898.7
opioid binding protein/cell adhesion molecule-like
chr16_-_12009735 0.04 ENST00000439887.2
ENST00000434724.2
G1 to S phase transition 1
chr8_+_81397876 0.04 ENST00000430430.1
zinc finger and BTB domain containing 10
chr2_+_160568978 0.04 ENST00000409175.1
ENST00000539065.1
ENST00000259050.4
ENST00000421037.1
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr14_+_72399833 0.03 ENST00000553530.1
ENST00000556437.1
regulator of G-protein signaling 6
chr17_+_30771279 0.03 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr6_-_94129244 0.03 ENST00000369303.4
ENST00000369297.1
EPH receptor A7
chr5_-_153857819 0.02 ENST00000231121.2
heart and neural crest derivatives expressed 1
chr16_+_29789561 0.01 ENST00000400752.4
zymogen granule protein 16
chr16_+_70380732 0.01 ENST00000302243.7
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
chr12_-_110318263 0.00 ENST00000318348.4
glycolipid transfer protein
chr19_+_47104493 0.00 ENST00000291295.9
ENST00000597743.1
calmodulin 3 (phosphorylase kinase, delta)
chr10_-_38146510 0.00 ENST00000395867.3
zinc finger protein 248

Network of associatons between targets according to the STRING database.

First level regulatory network of AGGUAGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:2000685 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.9 3.5 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.7 0.7 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.6 1.9 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.6 4.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.5 8.2 GO:0043589 skin morphogenesis(GO:0043589)
0.4 1.8 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.3 3.1 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.3 2.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.3 0.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 1.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.3 0.8 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 0.8 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 0.6 GO:0061386 closure of optic fissure(GO:0061386)
0.2 2.0 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 0.6 GO:0016095 polyprenol catabolic process(GO:0016095)
0.2 0.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 0.9 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.2 0.5 GO:1902534 single-organism membrane invagination(GO:1902534)
0.2 1.0 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 0.5 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.2 0.8 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 0.5 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.4 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.1 0.7 GO:0072719 cellular response to cisplatin(GO:0072719)
0.1 0.5 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 3.0 GO:0032607 interferon-alpha production(GO:0032607)
0.1 0.6 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.6 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 1.1 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.1 2.3 GO:0043586 tongue development(GO:0043586)
0.1 1.1 GO:0016081 synaptic vesicle docking(GO:0016081) positive regulation of pigment cell differentiation(GO:0050942)
0.1 1.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.4 GO:0048880 sensory system development(GO:0048880)
0.1 2.9 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 2.0 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 2.3 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.1 0.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.5 GO:0002118 aggressive behavior(GO:0002118)
0.0 1.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.4 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0022614 apical constriction(GO:0003383) membrane to membrane docking(GO:0022614) negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951) positive regulation of inclusion body assembly(GO:0090261)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 1.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.2 GO:0002176 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 1.8 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.4 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 1.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 2.6 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 1.1 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.8 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 1.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 2.0 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 1.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 1.2 GO:0048477 oogenesis(GO:0048477)
0.0 0.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.4 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.0 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.0 0.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.9 GO:0021510 spinal cord development(GO:0021510)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.9 GO:0045921 positive regulation of exocytosis(GO:0045921)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 13.0 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4 1.8 GO:0044611 nuclear pore inner ring(GO:0044611)
0.4 4.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.3 1.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 1.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 3.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.8 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.9 GO:0051286 cell tip(GO:0051286)
0.1 1.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.3 GO:0000145 exocyst(GO:0000145)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.9 GO:0031045 dense core granule(GO:0031045)
0.0 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.5 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 2.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 3.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.0 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.1 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.0 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 4.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.6 GO:0031904 endosome lumen(GO:0031904)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0035501 MH1 domain binding(GO:0035501)
1.0 13.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.9 3.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 1.8 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.3 0.8 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.2 0.6 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 1.0 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.5 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.4 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.6 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 1.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.9 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 1.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 2.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.7 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 2.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 2.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.0 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.7 GO:0048185 activin binding(GO:0048185)
0.0 1.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0070697 activin receptor binding(GO:0070697)
0.0 1.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 1.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.9 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 13.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 0.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 3.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.0 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 2.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 5.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins