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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ARID5A

Z-value: 0.78

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Transcription factors associated with ARID5A

Gene Symbol Gene ID Gene Info
ENSG00000196843.11 AT-rich interaction domain 5A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARID5Ahg19_v2_chr2_+_97203082_97203159,
hg19_v2_chr2_+_97202480_97202499
0.082.6e-01Click!

Activity profile of ARID5A motif

Sorted Z-values of ARID5A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_88323218 21.58 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500 host gene (non-protein coding)
chr3_-_112127981 20.54 ENST00000486726.2
RP11-231E6.1
chr2_-_217724767 13.75 ENST00000236979.2
transition protein 1 (during histone to protamine replacement)
chr3_+_101546827 8.71 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr12_+_8995832 8.54 ENST00000541459.1
alpha-2-macroglobulin-like 1
chr6_+_150920999 8.29 ENST00000367328.1
ENST00000367326.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr16_+_55542910 8.17 ENST00000262134.5
lysophosphatidylcholine acyltransferase 2
chr16_-_11375179 7.59 ENST00000312511.3
protamine 1
chr4_+_106631966 6.74 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing
chr2_+_152214098 5.44 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr6_-_74161977 5.25 ENST00000370318.1
ENST00000370315.3
Mab-21 domain containing 1
chr12_-_91572278 5.07 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
decorin
chr19_-_21950362 4.77 ENST00000358296.6
zinc finger protein 100
chr1_+_158815588 4.62 ENST00000438394.1
myeloid cell nuclear differentiation antigen
chr18_+_39766626 4.37 ENST00000593234.1
ENST00000585627.1
ENST00000591199.1
ENST00000586990.1
ENST00000593051.1
ENST00000593316.1
ENST00000591381.1
ENST00000585639.1
ENST00000589068.1
long intergenic non-protein coding RNA 907
chr6_+_151561085 4.25 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr10_-_21661870 4.15 ENST00000433460.1
RP11-275N1.1
chr6_-_52705641 4.05 ENST00000370989.2
glutathione S-transferase alpha 5
chr5_-_131892501 3.94 ENST00000450655.1
interleukin 5 (colony-stimulating factor, eosinophil)
chr10_+_32856764 3.91 ENST00000375030.2
ENST00000375028.3
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr12_-_4758159 3.89 ENST00000545990.2
A kinase (PRKA) anchor protein 3
chr12_-_8218997 3.85 ENST00000307637.4
complement component 3a receptor 1
chr2_+_196313239 3.76 ENST00000413290.1
AC064834.1
chr11_+_60197040 3.76 ENST00000300190.2
membrane-spanning 4-domains, subfamily A, member 5
chr11_+_60197069 3.65 ENST00000528905.1
ENST00000528093.1
membrane-spanning 4-domains, subfamily A, member 5
chr2_-_89545079 3.63 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr6_+_33048222 3.56 ENST00000428835.1
major histocompatibility complex, class II, DP beta 1
chr4_-_71532339 3.54 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr11_-_104480019 3.51 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
chr6_+_151561506 3.29 ENST00000253332.1
A kinase (PRKA) anchor protein 12
chr19_-_57988871 3.17 ENST00000596831.1
ENST00000601768.1
ENST00000356584.3
ENST00000600175.1
ENST00000425074.3
ENST00000343280.4
ENST00000427512.2
Uncharacterized protein
zinc finger protein 772
chrX_+_8432871 3.15 ENST00000381032.1
ENST00000453306.1
ENST00000444481.1
variable charge, X-linked 3B
chr6_-_33239712 3.06 ENST00000436044.2
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr5_-_19988339 3.04 ENST00000382275.1
cadherin 18, type 2
chr13_-_52703187 2.84 ENST00000355568.4
NIMA-related kinase 5
chr2_-_208989225 2.78 ENST00000264376.4
crystallin, gamma D
chr22_-_38699003 2.78 ENST00000451964.1
casein kinase 1, epsilon
chr3_-_141747950 2.74 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_+_54519242 2.73 ENST00000234827.1
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr11_-_114466477 2.67 ENST00000375478.3
neurexophilin and PC-esterase domain family, member 4
chr15_+_93749295 2.61 ENST00000599897.1
AC112693.2
chr14_-_90798418 2.50 ENST00000354366.3
NRDE-2, necessary for RNA interference, domain containing
chr6_-_133084580 2.50 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
vanin 2
chr5_-_86534822 2.45 ENST00000445770.2
Uncharacterized protein
chr16_+_10479906 2.43 ENST00000562527.1
ENST00000396560.2
ENST00000396559.1
ENST00000562102.1
ENST00000543967.1
ENST00000569939.1
ENST00000569900.1
activating transcription factor 7 interacting protein 2
chr3_+_113616317 2.42 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr3_-_106959424 2.41 ENST00000607801.1
ENST00000479612.2
ENST00000484698.1
ENST00000477210.2
ENST00000473636.1
long intergenic non-protein coding RNA 882
chr11_+_128563652 2.39 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr22_-_32766972 2.39 ENST00000382084.4
ENST00000382086.2
RFPL3 antisense
chr12_-_91546926 2.37 ENST00000550758.1
decorin
chr11_+_55029628 2.35 ENST00000417545.2
tripartite motif containing 48
chr11_-_102595681 2.33 ENST00000236826.3
matrix metallopeptidase 8 (neutrophil collagenase)
chr10_+_114710516 2.33 ENST00000542695.1
ENST00000346198.4
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr3_-_69171708 2.33 ENST00000420581.2
leiomodin 3 (fetal)
chr2_-_232395169 2.29 ENST00000305141.4
neuromedin U receptor 1
chr15_+_69307028 2.27 ENST00000388866.3
ENST00000530406.2
NADPH oxidase, EF-hand calcium binding domain 5
chr20_+_37590942 2.22 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr6_-_49834209 2.21 ENST00000507853.1
cysteine-rich secretory protein 1
chr11_-_114466471 2.19 ENST00000424261.2
neurexophilin and PC-esterase domain family, member 4
chr6_-_49712147 2.19 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr19_+_55014085 2.17 ENST00000351841.2
leukocyte-associated immunoglobulin-like receptor 2
chr6_+_31707725 2.16 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
mutS homolog 5
chr11_-_62477041 2.14 ENST00000433053.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr18_+_61554932 2.13 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr20_+_55904815 2.13 ENST00000371263.3
ENST00000345868.4
ENST00000371260.4
ENST00000418127.1
SPO11 meiotic protein covalently bound to DSB
chr6_-_49834240 2.12 ENST00000335847.4
cysteine-rich secretory protein 1
chr22_-_32767017 2.10 ENST00000400234.1
RFPL3 antisense
chr6_-_33048483 2.09 ENST00000419277.1
major histocompatibility complex, class II, DP alpha 1
chr12_+_10460417 2.07 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
killer cell lectin-like receptor subfamily D, member 1
chr8_-_86253888 2.06 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
carbonic anhydrase I
chr11_-_118305921 2.03 ENST00000532619.1
RP11-770J1.4
chr1_-_203320617 2.03 ENST00000354955.4
fibromodulin
chr17_+_35767301 2.02 ENST00000225396.6
ENST00000417170.1
ENST00000590005.1
ENST00000590957.1
transcriptional adaptor 2A
chrX_+_41583408 1.99 ENST00000302548.4
G protein-coupled receptor 82
chr3_-_87325728 1.97 ENST00000350375.2
POU class 1 homeobox 1
chr14_+_50291993 1.96 ENST00000595378.1
HCG1786899; PRO2610; Uncharacterized protein
chr18_-_5419797 1.93 ENST00000542146.1
ENST00000427684.2
erythrocyte membrane protein band 4.1-like 3
chr18_-_53069419 1.90 ENST00000570177.2
transcription factor 4
chr14_-_25045446 1.88 ENST00000216336.2
cathepsin G
chr7_-_140482926 1.88 ENST00000496384.2
v-raf murine sarcoma viral oncogene homolog B
chr12_+_9980069 1.86 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
killer cell lectin-like receptor subfamily F, member 1
chr22_-_23922448 1.85 ENST00000438703.1
ENST00000330377.2
immunoglobulin lambda-like polypeptide 1
chr1_-_23504176 1.85 ENST00000302291.4
leucine zipper protein 1
chr7_-_80551671 1.85 ENST00000419255.2
ENST00000544525.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr11_-_62476965 1.84 ENST00000405837.1
ENST00000531524.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr7_+_116593292 1.82 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
suppression of tumorigenicity 7
chr6_-_169654139 1.81 ENST00000366787.3
thrombospondin 2
chr8_+_11141925 1.79 ENST00000221086.3
myotubularin related protein 9
chr4_+_100737954 1.74 ENST00000296414.7
ENST00000512369.1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr19_+_55014013 1.73 ENST00000301202.2
leukocyte-associated immunoglobulin-like receptor 2
chr4_+_71226468 1.73 ENST00000226460.4
submaxillary gland androgen regulated protein 3A
chr1_-_150669604 1.73 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr13_-_41706864 1.70 ENST00000379485.1
ENST00000499385.2
kelch repeat and BTB (POZ) domain containing 6
chr1_-_158656488 1.70 ENST00000368147.4
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chrX_+_37850026 1.68 ENST00000341016.3
chromosome X open reading frame 27
chr15_-_58571445 1.67 ENST00000558231.1
aldehyde dehydrogenase 1 family, member A2
chr3_+_134204881 1.67 ENST00000511574.1
ENST00000337090.3
ENST00000383229.3
centrosomal protein 63kDa
chr5_+_159848854 1.67 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr12_+_32260085 1.66 ENST00000548411.1
ENST00000281474.5
ENST00000551086.1
bicaudal D homolog 1 (Drosophila)
chr1_+_160336851 1.66 ENST00000302101.5
nescient helix loop helix 1
chr19_-_44174305 1.65 ENST00000601723.1
ENST00000339082.3
plasminogen activator, urokinase receptor
chr17_-_37844267 1.63 ENST00000579146.1
ENST00000378011.4
ENST00000429199.2
ENST00000300658.4
post-GPI attachment to proteins 3
chr1_+_13910194 1.61 ENST00000376057.4
ENST00000510906.1
podoplanin
chr12_+_72080253 1.61 ENST00000549735.1
transmembrane protein 19
chr3_+_171561127 1.59 ENST00000334567.5
ENST00000450693.1
transmembrane protein 212
chr2_-_228244013 1.59 ENST00000304568.3
transmembrane 4 L six family member 20
chr1_-_216978709 1.55 ENST00000360012.3
estrogen-related receptor gamma
chr17_-_2996290 1.54 ENST00000331459.1
olfactory receptor, family 1, subfamily D, member 2
chr1_-_153013588 1.54 ENST00000360379.3
small proline-rich protein 2D
chr15_-_52404921 1.54 ENST00000561198.1
ENST00000260442.3
BCL2-like 10 (apoptosis facilitator)
chr1_-_46642154 1.53 ENST00000540385.1
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr6_+_83777374 1.52 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
dopey family member 1
chr1_+_163039143 1.51 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
regulator of G-protein signaling 4
chr1_+_104159999 1.51 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr5_-_131879205 1.50 ENST00000231454.1
interleukin 5 (colony-stimulating factor, eosinophil)
chr9_-_138391692 1.50 ENST00000429260.2
chromosome 9 open reading frame 116
chr1_+_115572415 1.49 ENST00000256592.1
thyroid stimulating hormone, beta
chr3_-_112320749 1.48 ENST00000610103.1
RP11-572C15.6
chr8_+_24298531 1.47 ENST00000175238.6
ADAM metallopeptidase domain 7
chr19_-_44174330 1.46 ENST00000340093.3
plasminogen activator, urokinase receptor
chrX_+_37639302 1.46 ENST00000545017.1
ENST00000536160.1
cytochrome b-245, beta polypeptide
chr10_-_15902449 1.45 ENST00000277632.3
family with sequence similarity 188, member A
chr3_+_135741576 1.45 ENST00000334546.2
protein phosphatase 2, regulatory subunit B'', alpha
chr11_-_59950622 1.44 ENST00000323961.3
ENST00000412309.2
membrane-spanning 4-domains, subfamily A, member 6A
chr16_+_31366455 1.43 ENST00000268296.4
integrin, alpha X (complement component 3 receptor 4 subunit)
chr21_-_19775973 1.43 ENST00000284885.3
transmembrane protease, serine 15
chr3_-_194072019 1.43 ENST00000429275.1
ENST00000323830.3
carboxypeptidase N, polypeptide 2
chr10_-_61720640 1.42 ENST00000521074.1
ENST00000444900.1
chromosome 10 open reading frame 40
chr17_-_6554877 1.42 ENST00000225728.3
ENST00000575197.1
mediator complex subunit 31
chrX_+_107288239 1.42 ENST00000217957.5
V-set and immunoglobulin domain containing 1
chr7_-_7782204 1.41 ENST00000418534.2
AC007161.5
chr6_-_49712123 1.41 ENST00000263045.4
cysteine-rich secretory protein 3
chr1_+_158901329 1.39 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
pyrin and HIN domain family, member 1
chrX_-_100641155 1.39 ENST00000372880.1
ENST00000308731.7
Bruton agammaglobulinemia tyrosine kinase
chr4_+_88754069 1.39 ENST00000395102.4
ENST00000497649.2
matrix extracellular phosphoglycoprotein
chr20_-_18447667 1.38 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
double zinc ribbon and ankyrin repeat domains 1
chr12_-_96390063 1.36 ENST00000541929.1
histidine ammonia-lyase
chr11_+_76745385 1.35 ENST00000533140.1
ENST00000354301.5
ENST00000528622.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr22_+_32754139 1.34 ENST00000382088.3
ret finger protein-like 3
chr10_+_114710425 1.34 ENST00000352065.5
ENST00000369395.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr8_+_24298597 1.34 ENST00000380789.1
ADAM metallopeptidase domain 7
chr16_+_31366536 1.34 ENST00000562522.1
integrin, alpha X (complement component 3 receptor 4 subunit)
chr1_+_248020481 1.33 ENST00000366481.3
tripartite motif containing 58
chrX_-_45060135 1.32 ENST00000398000.2
ENST00000377934.4
chromosome X open reading frame 36
chr10_+_70847852 1.30 ENST00000242465.3
serglycin
chrX_-_19988382 1.27 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
chromosome X open reading frame 23
chr4_-_47983519 1.27 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chr1_+_241695670 1.26 ENST00000366557.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr6_+_26156551 1.25 ENST00000304218.3
histone cluster 1, H1e
chr10_+_47746929 1.25 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
annexin A8-like 2
Protein LOC100996760
chr6_+_32605195 1.25 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr11_+_73661364 1.24 ENST00000339764.1
DnaJ (Hsp40) homolog, subfamily B, member 13
chr12_-_10542617 1.24 ENST00000240618.6
killer cell lectin-like receptor subfamily K, member 1
chr7_-_19748640 1.23 ENST00000222567.5
TWIST neighbor
chr2_+_171034646 1.23 ENST00000409044.3
ENST00000408978.4
myosin IIIB
chr9_+_116207007 1.23 ENST00000374140.2
regulator of G-protein signaling 3
chr4_+_56212270 1.23 ENST00000264228.4
steroid 5 alpha-reductase 3
chr22_-_29457832 1.23 ENST00000216071.4
chromosome 22 open reading frame 31
chr12_+_21207503 1.22 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr19_+_36132631 1.21 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ets variant 2
chrX_+_15767971 1.19 ENST00000479740.1
ENST00000454127.2
carbonic anhydrase VB, mitochondrial
chr3_+_134204551 1.19 ENST00000332047.5
ENST00000354446.3
centrosomal protein 63kDa
chr1_+_86934526 1.18 ENST00000394711.1
chloride channel accessory 1
chr4_+_71248795 1.18 ENST00000304915.3
submaxillary gland androgen regulated protein 3B
chr1_+_178310581 1.16 ENST00000462775.1
RAS protein activator like 2
chr5_+_159848807 1.15 ENST00000352433.5
pituitary tumor-transforming 1
chr11_-_59950519 1.15 ENST00000528851.1
membrane-spanning 4-domains, subfamily A, member 6A
chr18_+_61575200 1.14 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr11_-_89653576 1.09 ENST00000420869.1
tripartite motif containing 49D1
chr4_+_68424434 1.09 ENST00000265404.2
ENST00000396225.1
signal transducing adaptor family member 1
chr5_-_39274617 1.09 ENST00000510188.1
FYN binding protein
chr21_+_40824003 1.08 ENST00000452550.1
SH3 domain binding glutamic acid-rich protein
chr14_+_39703112 1.07 ENST00000555143.1
ENST00000280082.3
melanoma inhibitory activity 2
chr15_+_59063478 1.07 ENST00000559228.1
ENST00000450403.2
family with sequence similarity 63, member B
chr1_+_117963209 1.06 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr6_-_33239612 1.06 ENST00000482399.1
ENST00000445902.2
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr1_-_146054494 1.06 ENST00000401009.2
neuroblastoma breakpoint family, member 11
chr1_+_241695424 1.05 ENST00000366558.3
ENST00000366559.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr12_-_15114603 1.04 ENST00000228945.4
Rho GDP dissociation inhibitor (GDI) beta
chr22_-_23922410 1.03 ENST00000249053.3
immunoglobulin lambda-like polypeptide 1
chr1_+_170904612 1.01 ENST00000367759.4
ENST00000367758.3
maestro heat-like repeat family member 9
chr2_+_157330081 0.99 ENST00000409674.1
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr5_-_55412774 0.99 ENST00000434982.2
ankyrin repeat domain 55
chr17_-_2966901 0.99 ENST00000575751.1
olfactory receptor, family 1, subfamily D, member 5
chr1_+_104293028 0.99 ENST00000370079.3
amylase, alpha 1C (salivary)
chr20_+_30795664 0.98 ENST00000375749.3
ENST00000375730.3
ENST00000539210.1
protein O-fucosyltransferase 1
chr6_-_133055896 0.98 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
vanin 3
chr11_-_112034803 0.98 ENST00000528832.1
interleukin 18 (interferon-gamma-inducing factor)
chr12_-_96390108 0.96 ENST00000538703.1
ENST00000261208.3
histidine ammonia-lyase
chrX_+_70521584 0.96 ENST00000373829.3
ENST00000538820.1
integrin beta 1 binding protein (melusin) 2
chr10_-_102027420 0.96 ENST00000354105.4
CWF19-like 1, cell cycle control (S. pombe)
chr10_+_96443378 0.95 ENST00000285979.6
cytochrome P450, family 2, subfamily C, polypeptide 18
chr3_+_148447887 0.94 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
angiotensin II receptor, type 1
chr7_+_134528635 0.94 ENST00000445569.2
caldesmon 1
chr12_+_75874984 0.93 ENST00000550491.1
GLI pathogenesis-related 1
chr20_-_18477862 0.93 ENST00000337227.4
retinoblastoma binding protein 9
chr4_+_71296204 0.93 ENST00000413702.1
mucin 7, secreted
chr2_-_183106641 0.93 ENST00000346717.4
phosphodiesterase 1A, calmodulin-dependent
chr11_-_59950486 0.92 ENST00000426738.2
ENST00000533023.1
ENST00000420732.2
membrane-spanning 4-domains, subfamily A, member 6A
chr6_+_20534672 0.91 ENST00000274695.4
ENST00000378624.4
CDK5 regulatory subunit associated protein 1-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ARID5A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.7 GO:0007290 spermatid nucleus elongation(GO:0007290)
2.0 8.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
1.8 5.4 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
1.4 4.1 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.8 3.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.8 2.3 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.8 2.3 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.7 2.7 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.7 2.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.6 7.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.6 3.7 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.5 1.6 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.5 7.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.5 1.4 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.5 2.9 GO:0098535 de novo centriole assembly(GO:0098535)
0.5 1.4 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.5 2.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.4 1.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.4 1.2 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.4 1.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.4 2.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 1.9 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.4 1.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.4 1.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.3 3.5 GO:0015939 pantothenate metabolic process(GO:0015939)
0.3 1.7 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.3 2.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.3 1.8 GO:0003350 pulmonary myocardium development(GO:0003350)
0.3 0.9 GO:0048867 stem cell fate determination(GO:0048867)
0.3 1.5 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.3 0.9 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.3 4.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 1.9 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.3 0.8 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.3 1.0 GO:0071461 cellular response to redox state(GO:0071461)
0.3 3.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 5.2 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.2 1.0 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.2 1.2 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.2 2.2 GO:0051026 chiasma assembly(GO:0051026)
0.2 1.9 GO:0070943 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.2 0.4 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 0.8 GO:0072660 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.4 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.2 4.6 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.2 1.0 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.2 0.6 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 2.1 GO:0090220 meiotic telomere clustering(GO:0045141) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.2 1.7 GO:0035799 ureter maturation(GO:0035799)
0.2 5.4 GO:0030728 ovulation(GO:0030728)
0.2 0.9 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.2 1.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 0.7 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 1.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 4.0 GO:0034389 lipid particle organization(GO:0034389)
0.2 0.7 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.2 6.1 GO:0030261 chromosome condensation(GO:0030261)
0.1 0.3 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.6 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.6 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.7 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 1.8 GO:0001842 neural fold formation(GO:0001842)
0.1 0.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.5 GO:0003409 optic cup structural organization(GO:0003409)
0.1 2.8 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 0.9 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 3.9 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.6 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.1 0.6 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 2.4 GO:0035855 megakaryocyte development(GO:0035855)
0.1 2.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 2.8 GO:0045143 homologous chromosome segregation(GO:0045143)
0.1 1.0 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.7 GO:0009804 coumarin metabolic process(GO:0009804)
0.1 0.7 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 2.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 7.6 GO:0031295 T cell costimulation(GO:0031295)
0.1 0.7 GO:0032074 regulation of endodeoxyribonuclease activity(GO:0032071) negative regulation of nuclease activity(GO:0032074)
0.1 2.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.5 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 1.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 2.8 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 1.5 GO:0033189 response to vitamin A(GO:0033189)
0.1 0.6 GO:0001675 acrosome assembly(GO:0001675)
0.1 3.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 1.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 2.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 5.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.2 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 1.4 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 0.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 2.6 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 2.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.2 GO:0035989 tendon development(GO:0035989) tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 1.6 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 0.7 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 2.0 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 1.3 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.4 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 7.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 2.8 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.0 2.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 1.2 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 5.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:1901985 positive regulation of protein acetylation(GO:1901985)
0.0 1.3 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 2.6 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 1.2 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.4 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.8 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 1.5 GO:0007292 female gamete generation(GO:0007292)
0.0 1.9 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 0.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 1.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 1.8 GO:2000181 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.0 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.7 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 1.3 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 6.7 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.4 GO:0061053 somite development(GO:0061053)
0.0 0.2 GO:0032620 interleukin-17 production(GO:0032620)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.8 GO:0051646 mitochondrion localization(GO:0051646)
0.0 0.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.6 GO:0030097 hemopoiesis(GO:0030097)
0.0 0.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.9 GO:0006400 tRNA modification(GO:0006400)
0.0 1.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.3 GO:0045861 negative regulation of proteolysis(GO:0045861)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.9 GO:0006936 muscle contraction(GO:0006936)
0.0 0.2 GO:0002323 natural killer cell activation involved in immune response(GO:0002323)
0.0 0.8 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 15.0 GO:0000788 nuclear nucleosome(GO:0000788)
1.0 4.1 GO:1990745 EARP complex(GO:1990745)
0.6 3.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.5 7.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.5 0.9 GO:0097679 other organism cytoplasm(GO:0097679)
0.4 8.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 3.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 1.7 GO:0033648 host cell cytoplasm(GO:0030430) host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) host cell cytoplasm part(GO:0033655) tubulin complex(GO:0045298)
0.3 0.9 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.3 3.2 GO:0071438 invadopodium membrane(GO:0071438)
0.3 1.4 GO:0070847 core mediator complex(GO:0070847)
0.3 1.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 1.7 GO:0032437 cuticular plate(GO:0032437)
0.2 1.2 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 1.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 1.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 2.2 GO:0032300 mismatch repair complex(GO:0032300)
0.1 1.5 GO:0005802 trans-Golgi network(GO:0005802)
0.1 2.5 GO:0042588 zymogen granule(GO:0042588)
0.1 1.9 GO:0033270 paranode region of axon(GO:0033270)
0.1 1.0 GO:0042611 MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.1 1.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 8.2 GO:0005811 lipid particle(GO:0005811)
0.1 8.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.8 GO:0097427 microtubule bundle(GO:0097427)
0.1 3.6 GO:0000786 nucleosome(GO:0000786)
0.1 1.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 4.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 8.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 2.8 GO:0008305 integrin complex(GO:0008305)
0.1 0.5 GO:0000125 PCAF complex(GO:0000125)
0.1 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.7 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.9 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0001939 female pronucleus(GO:0001939)
0.0 1.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0005602 complement component C1 complex(GO:0005602)
0.0 1.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 5.4 GO:0072562 blood microparticle(GO:0072562)
0.0 3.0 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 2.0 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 27.9 GO:0005615 extracellular space(GO:0005615)
0.0 1.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 7.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.4 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 1.0 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 1.2 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.1 GO:0043194 axon initial segment(GO:0043194)
0.0 0.6 GO:0045095 keratin filament(GO:0045095)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
1.8 5.4 GO:0005137 interleukin-5 receptor binding(GO:0005137)
1.0 3.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.7 3.6 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.7 2.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.7 3.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.6 2.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.5 7.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.5 1.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.5 1.4 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.4 1.7 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.4 1.2 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.4 2.3 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.4 1.5 GO:0016160 amylase activity(GO:0016160)
0.3 3.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 1.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 3.8 GO:0004875 complement receptor activity(GO:0004875)
0.3 2.1 GO:0004064 arylesterase activity(GO:0004064)
0.2 1.0 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.2 1.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 1.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.2 4.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 1.9 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.2 1.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 5.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 2.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 0.9 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.2 5.1 GO:0042605 peptide antigen binding(GO:0042605)
0.2 0.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 3.8 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1 0.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 1.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 1.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.7 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 1.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.7 GO:0004771 sterol esterase activity(GO:0004771)
0.1 1.5 GO:0089720 caspase binding(GO:0089720)
0.1 1.6 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 3.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 5.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 12.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 1.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 7.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.9 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 1.3 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 1.6 GO:0070330 aromatase activity(GO:0070330)
0.1 1.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 8.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 4.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 2.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 2.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 1.0 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 1.9 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 2.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 5.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.4 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 1.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 2.7 GO:0001105 RNA polymerase II activating transcription factor binding(GO:0001102) RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 4.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.4 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 8.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.5 GO:0005518 collagen binding(GO:0005518)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.2 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 2.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 3.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 3.2 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.6 GO:0005179 hormone activity(GO:0005179)
0.0 1.8 GO:0008201 heparin binding(GO:0008201)
0.0 5.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0008289 lipid binding(GO:0008289)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0032183 SUMO binding(GO:0032183)
0.0 0.9 GO:0003725 double-stranded RNA binding(GO:0003725)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 4.8 PID IL5 PATHWAY IL5-mediated signaling events
0.1 3.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 1.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 23.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 4.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 1.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 6.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 6.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.1 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 8.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.3 3.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.3 7.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 3.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 0.9 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.2 2.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 2.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 4.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 5.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 6.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 3.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.9 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 2.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 4.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.7 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 2.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 8.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME SIGNALING BY THE B CELL RECEPTOR BCR Genes involved in Signaling by the B Cell Receptor (BCR)
0.0 1.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 3.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 2.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.0 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 1.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.0 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling