GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
ARNT Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000143437.16	aryl hydrocarbon receptor nuclear translocator

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ARNT	hg19_v2_chr1_-_150849047_150849085, hg19_v2_chr1_-_150849174_150849200	-0.34	2.5e-07	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chrX_+_77359671 Show fit	113.67	ENST00000373316.4	PGK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoglycerate kinase 1
chrX_+_77359726 Show fit	110.68	ENST00000442431.1	PGK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoglycerate kinase 1
chr11_-_64014379 Show fit	102.48	ENST00000309318.3	PPP1R14B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr1_-_8939265 Show fit	94.11	ENST00000489867.1	ENO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	enolase 1, (alpha)
chr2_-_10587897 Show fit	86.02	ENST00000405333.1 ENST00000443218.1	ODC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ornithine decarboxylase 1
chrX_+_23685653 Show fit	78.85	ENST00000379331.3	PRDX4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	peroxiredoxin 4
chrX_+_23685563 Show fit	69.12	ENST00000379341.4	PRDX4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	peroxiredoxin 4
chr17_-_47492164 Show fit	64.01	ENST00000512041.2 ENST00000446735.1 ENST00000504124.1	PHB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prohibitin
chr3_-_195808980 Show fit	59.39	ENST00000360110.4	TFRC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transferrin receptor
chr19_+_50180507 Show fit	59.12	ENST00000454376.2 ENST00000524771.1	PRMT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein arginine methyltransferase 1
chr2_+_201170770 Show fit	57.78	ENST00000409988.3 ENST00000409385.1	SPATS2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spermatogenesis associated, serine-rich 2-like
chr3_-_195808952 Show fit	57.60	ENST00000540528.1 ENST00000392396.3 ENST00000535031.1 ENST00000420415.1	TFRC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transferrin receptor
chr2_+_201171372 Show fit	57.57	ENST00000409140.3	SPATS2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spermatogenesis associated, serine-rich 2-like
chr1_-_159894319 Show fit	56.22	ENST00000320307.4	TAGLN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transgelin 2
chr19_-_10530784 Show fit	55.93	ENST00000593124.1	CDC37 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle 37
chr15_+_52311398 Show fit	55.36	ENST00000261845.5	MAPK6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase 6
chr1_-_8938736 Show fit	52.15	ENST00000234590.4	ENO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	enolase 1, (alpha)
chr19_+_50180409 Show fit	51.15	ENST00000391851.4	PRMT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein arginine methyltransferase 1
chr12_-_58146128 Show fit	50.89	ENST00000551800.1 ENST00000549606.1 ENST00000257904.6	CDK4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 4
chr12_-_58146048 Show fit	48.68	ENST00000547281.1 ENST00000546489.1 ENST00000552388.1 ENST00000540325.1 ENST00000312990.6	CDK4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 4
chr15_+_40453204 Show fit	47.84	ENST00000287598.6 ENST00000412359.3	BUB1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BUB1 mitotic checkpoint serine/threonine kinase B
chr7_+_100464760 Show fit	46.06	ENST00000200457.4	TRIP6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thyroid hormone receptor interactor 6
chr19_+_50180317 Show fit	44.92	ENST00000534465.1	PRMT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein arginine methyltransferase 1
chr3_-_49066811 Show fit	43.45	ENST00000442157.1 ENST00000326739.4	IMPDH2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	IMP (inosine 5'-monophosphate) dehydrogenase 2
chr2_+_216176540 Show fit	42.31	ENST00000236959.9	ATIC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr2_+_216176761 Show fit	42.25	ENST00000540518.1 ENST00000435675.1	ATIC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr15_+_74218787 Show fit	41.87	ENST00000261921.7	LOXL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysyl oxidase-like 1
chr17_-_5342380 Show fit	41.19	ENST00000225698.4	C1QBP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 1, q subcomponent binding protein
chr3_-_149688655 Show fit	41.17	ENST00000461930.1 ENST00000423691.2 ENST00000490975.1 ENST00000461868.1 ENST00000452853.2	PFN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	profilin 2
chr1_-_43638168 Show fit	40.39	ENST00000431635.2	EBNA1BP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	EBNA1 binding protein 2
chr11_+_18416103 Show fit	39.36	ENST00000543445.1 ENST00000430553.2 ENST00000396222.2 ENST00000535451.1	LDHA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lactate dehydrogenase A
chr11_-_122931881 Show fit	39.07	ENST00000526110.1 ENST00000227378.3	HSPA8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock 70kDa protein 8
chrX_-_16887963 Show fit	38.42	ENST00000380084.4	RBBP7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	retinoblastoma binding protein 7
chr12_-_120907374 Show fit	38.41	ENST00000550458.1	SRSF9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/arginine-rich splicing factor 9
chr6_+_34204642 Show fit	37.87	ENST00000347617.6 ENST00000401473.3 ENST00000311487.5 ENST00000447654.1 ENST00000395004.3	HMGA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group AT-hook 1
chr17_-_48474828 Show fit	37.57	ENST00000576448.1 ENST00000225972.7	LRRC59 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich repeat containing 59
chr7_+_56119323 Show fit	37.38	ENST00000275603.4 ENST00000335503.3 ENST00000540286.1	CCT6A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chaperonin containing TCP1, subunit 6A (zeta 1)
chrX_+_69509927 Show fit	37.25	ENST00000374403.3	KIF4A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kinesin family member 4A
chr7_-_6523688 Show fit	36.85	ENST00000490996.1	KDELR2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr11_+_18416133 Show fit	36.68	ENST00000227157.4 ENST00000478970.2 ENST00000495052.1	LDHA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lactate dehydrogenase A
chr1_-_26232951 Show fit	36.15	ENST00000426559.2 ENST00000455785.2	STMN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stathmin 1
chr6_-_8102714 Show fit	36.01	ENST00000502429.1 ENST00000429723.2 ENST00000507463.1 ENST00000379715.5	EEF1E1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation elongation factor 1 epsilon 1
chr1_+_19578033 Show fit	35.94	ENST00000330263.4	MRTO4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mRNA turnover 4 homolog (S. cerevisiae)
chr12_+_64798095 Show fit	35.87	ENST00000332707.5	XPOT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	exportin, tRNA
chr17_-_40075219 Show fit	35.54	ENST00000537919.1 ENST00000352035.2 ENST00000353196.1 ENST00000393896.2	ACLY Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP citrate lyase
chr9_+_112542591 Show fit	35.15	ENST00000483909.1 ENST00000314527.4 ENST00000413420.1 ENST00000302798.7 ENST00000555236.1 ENST00000510514.5	PALM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit PALM2-AKAP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit AKAP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	paralemmin 2 PALM2-AKAP2 readthrough A kinase (PRKA) anchor protein 2
chr17_-_47492236 Show fit	35.08	ENST00000434917.2 ENST00000300408.3 ENST00000511832.1 ENST00000419140.2	PHB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prohibitin
chr11_-_64013663 Show fit	34.67	ENST00000392210.2	PPP1R14B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr3_-_149688896 Show fit	34.66	ENST00000239940.7	PFN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	profilin 2
chr12_-_120907459 Show fit	34.16	ENST00000229390.3	SRSF9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/arginine-rich splicing factor 9
chr20_+_56964253 Show fit	33.12	ENST00000395802.3	VAPB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	VAMP (vesicle-associated membrane protein)-associated protein B and C
chr2_+_201171064 Show fit	32.93	ENST00000451764.2	SPATS2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spermatogenesis associated, serine-rich 2-like
chr5_-_131563501 Show fit	32.92	ENST00000401867.1 ENST00000379086.1 ENST00000418055.1 ENST00000453286.1 ENST00000166534.4	P4HA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prolyl 4-hydroxylase, alpha polypeptide II
chr17_+_36908984 Show fit	32.65	ENST00000225426.4 ENST00000579088.1	PSMB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, beta type, 3
chr3_+_52719936 Show fit	32.62	ENST00000418458.1 ENST00000394799.2	GNL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	guanine nucleotide binding protein-like 3 (nucleolar)
chr22_+_20105259 Show fit	31.96	ENST00000416427.1 ENST00000421656.1 ENST00000423859.1 ENST00000418705.2	RANBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAN binding protein 1
chr14_+_56046990 Show fit	31.87	ENST00000438792.2 ENST00000395314.3 ENST00000395308.1	KTN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kinectin 1 (kinesin receptor)
chr3_+_5020801 Show fit	31.80	ENST00000256495.3	BHLHE40 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	basic helix-loop-helix family, member e40
chr19_-_47353547 Show fit	31.75	ENST00000601498.1	AP2S1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adaptor-related protein complex 2, sigma 1 subunit
chr17_+_49337881 Show fit	31.62	ENST00000225298.7	UTP18 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UTP18 small subunit (SSU) processome component homolog (yeast)
chr5_+_170814803 Show fit	31.37	ENST00000521672.1 ENST00000351986.6 ENST00000393820.2 ENST00000523622.1	NPM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr7_-_6523755 Show fit	31.19	ENST00000436575.1 ENST00000258739.4	DAGLB Links Ensembl NCBI GeneCards UniProt NextProt Show fit KDELR2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	diacylglycerol lipase, beta KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr11_-_6704513 Show fit	30.75	ENST00000532203.1 ENST00000288937.6	MRPL17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L17
chr1_-_43637915 Show fit	30.14	ENST00000236051.2	EBNA1BP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	EBNA1 binding protein 2
chr12_+_120907622 Show fit	30.08	ENST00000392509.2 ENST00000549649.1 ENST00000548342.1	DYNLL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dynein, light chain, LC8-type 1
chr12_+_131356582 Show fit	30.05	ENST00000448750.3 ENST00000541630.1 ENST00000392369.2 ENST00000254675.3 ENST00000535090.1 ENST00000392367.3	RAN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAN, member RAS oncogene family
chr15_+_79603404 Show fit	29.95	ENST00000299705.5	TMED3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane emp24 protein transport domain containing 3
chr12_+_6977258 Show fit	29.70	ENST00000488464.2 ENST00000535434.1 ENST00000493987.1	TPI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	triosephosphate isomerase 1
chr5_+_34656569 Show fit	29.69	ENST00000428746.2	RAI14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	retinoic acid induced 14
chr16_+_3070356 Show fit	29.55	ENST00000341627.5 ENST00000575124.1 ENST00000575836.1	TNFRSF12A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor receptor superfamily, member 12A
chr14_-_64010046 Show fit	29.49	ENST00000337537.3	PPP2R5E Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr16_+_3070313 Show fit	29.21	ENST00000326577.4	TNFRSF12A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor receptor superfamily, member 12A
chr3_-_57583185 Show fit	29.10	ENST00000463880.1	ARF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor 4
chr4_+_57301896 Show fit	29.02	ENST00000514888.1 ENST00000264221.2 ENST00000505164.1	PAICS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr17_-_73178599 Show fit	28.93	ENST00000578238.1	SUMO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small ubiquitin-like modifier 2
chr3_-_145878954 Show fit	28.92	ENST00000282903.5 ENST00000360060.3	PLOD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr12_-_50677255 Show fit	28.88	ENST00000551691.1 ENST00000394943.3 ENST00000341247.4	LIMA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM domain and actin binding 1
chr5_+_68530668 Show fit	28.84	ENST00000506563.1	CDK7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 7
chr1_-_26233423 Show fit	28.67	ENST00000357865.2	STMN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stathmin 1
chr14_+_56046914 Show fit	28.39	ENST00000413890.2 ENST00000395309.3 ENST00000554567.1 ENST00000555498.1	KTN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kinectin 1 (kinesin receptor)
chr13_+_27998681 Show fit	28.22	ENST00000381140.4	GTF3A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	general transcription factor IIIA
chr9_+_112542572 Show fit	28.13	ENST00000374530.3	PALM2-AKAP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PALM2-AKAP2 readthrough
chr6_-_43197189 Show fit	28.11	ENST00000509253.1 ENST00000393987.2 ENST00000230431.6	DNPH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr20_-_49547910 Show fit	28.02	ENST00000396032.3	ADNP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	activity-dependent neuroprotector homeobox
chr8_-_102218292 Show fit	28.00	ENST00000518336.1 ENST00000520454.1	ZNF706 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 706
chr11_+_844067 Show fit	27.70	ENST00000397406.1 ENST00000409543.2 ENST00000525201.1	TSPAN4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tetraspanin 4
chr19_-_47354023 Show fit	27.61	ENST00000601649.1 ENST00000599990.1 ENST00000352203.4	AP2S1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adaptor-related protein complex 2, sigma 1 subunit
chr5_+_34656331 Show fit	27.56	ENST00000265109.3	RAI14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	retinoic acid induced 14
chr1_+_47799446 Show fit	26.99	ENST00000371873.5	CMPK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr9_-_2844058 Show fit	26.98	ENST00000397885.2	KIAA0020 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA0020
chr14_+_62162258 Show fit	26.69	ENST00000337138.4 ENST00000394997.1	HIF1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr3_+_100211412 Show fit	25.79	ENST00000323523.4 ENST00000403410.1 ENST00000449609.1	TMEM45A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 45A
chr3_-_185542817 Show fit	25.72	ENST00000382199.2	IGF2BP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin-like growth factor 2 mRNA binding protein 2
chr19_-_291133 Show fit	25.72	ENST00000327790.3	PPAP2C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidic acid phosphatase type 2C
chr19_-_40336969 Show fit	25.65	ENST00000599134.1 ENST00000597634.1 ENST00000598417.1 ENST00000601274.1 ENST00000594309.1 ENST00000221801.3	FBL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fibrillarin
chr2_-_179315490 Show fit	25.58	ENST00000487082.1	PRKRA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase, interferon-inducible double stranded RNA dependent activator
chr14_-_54908043 Show fit	25.49	ENST00000556113.1 ENST00000553660.1 ENST00000395573.4 ENST00000557690.1 ENST00000216416.4	CNIH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cornichon family AMPA receptor auxiliary protein 1
chr2_+_187350883 Show fit	25.49	ENST00000337859.6	ZC3H15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger CCCH-type containing 15
chr5_+_138609441 Show fit	25.35	ENST00000509990.1 ENST00000506147.1 ENST00000512107.1	MATR3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	matrin 3
chr7_+_6048856 Show fit	25.26	ENST00000223029.3 ENST00000400479.2 ENST00000395236.2	AIMP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chrX_+_153672468 Show fit	25.11	ENST00000393600.3	FAM50A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 50, member A
chr3_-_185542761 Show fit	25.09	ENST00000457616.2 ENST00000346192.3	IGF2BP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin-like growth factor 2 mRNA binding protein 2
chr19_-_47354082 Show fit	25.02	ENST00000593442.1 ENST00000263270.6	AP2S1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adaptor-related protein complex 2, sigma 1 subunit
chr18_+_9913977 Show fit	25.02	ENST00000400000.2 ENST00000340541.4	VAPA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr13_-_31038370 Show fit	24.93	ENST00000399489.1 ENST00000339872.4	HMGB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group box 1
chr12_+_6643676 Show fit	24.81	ENST00000396856.1 ENST00000396861.1	GAPDH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glyceraldehyde-3-phosphate dehydrogenase
chr1_+_87170577 Show fit	24.78	ENST00000482504.1	SH3GLB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3-domain GRB2-like endophilin B1
chr2_+_198365122 Show fit	24.71	ENST00000604458.1	HSPE1-MOB4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	HSPE1-MOB4 readthrough
chr16_-_81129845 Show fit	24.53	ENST00000569885.1 ENST00000566566.1	GCSH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glycine cleavage system protein H (aminomethyl carrier)
chr1_-_6269448 Show fit	24.37	ENST00000465335.1	RPL22 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L22
chr5_+_49962495 Show fit	24.35	ENST00000515175.1	PARP8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	poly (ADP-ribose) polymerase family, member 8
chr15_-_65282232 Show fit	24.18	ENST00000416889.2	SPG21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr1_-_6269304 Show fit	24.15	ENST00000471204.1	RPL22 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L22
chr6_-_7313381 Show fit	23.98	ENST00000489567.1 ENST00000479365.1 ENST00000462112.1 ENST00000397511.2 ENST00000534851.1 ENST00000474597.1 ENST00000244763.4	SSR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal sequence receptor, alpha
chr17_+_40985407 Show fit	23.63	ENST00000586114.1 ENST00000590720.1 ENST00000585805.1 ENST00000541124.1 ENST00000441946.2 ENST00000591152.1 ENST00000589469.1 ENST00000293362.3 ENST00000592169.1	PSME3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr20_+_31407692 Show fit	23.21	ENST00000375571.5	MAPRE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule-associated protein, RP/EB family, member 1
chr4_-_39529049 Show fit	23.19	ENST00000501493.2 ENST00000509391.1 ENST00000507089.1	UGDH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UDP-glucose 6-dehydrogenase
chr15_+_45315302 Show fit	23.10	ENST00000267814.9	SORD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sorbitol dehydrogenase
chr1_-_6259613 Show fit	23.06	ENST00000465387.1	RPL22 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L22
chr22_+_24236191 Show fit	23.02	ENST00000215754.7	MIF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr11_-_118972575 Show fit	22.95	ENST00000432443.2	DPAGT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr3_+_122785895 Show fit	22.82	ENST00000316218.7	PDIA5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein disulfide isomerase family A, member 5
chr1_-_26232522 Show fit	22.79	ENST00000399728.1	STMN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stathmin 1
chr1_-_43833628 Show fit	22.55	ENST00000413844.2 ENST00000372458.3	ELOVL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ELOVL fatty acid elongase 1
chr17_+_7476136 Show fit	22.50	ENST00000582169.1 ENST00000578754.1 ENST00000578495.1 ENST00000293831.8 ENST00000380512.5 ENST00000585024.1 ENST00000583802.1 ENST00000577269.1 ENST00000584784.1 ENST00000582746.1	EIF4A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 4A1
chr15_-_65282274 Show fit	22.49	ENST00000204566.2	SPG21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr2_+_113403434 Show fit	22.37	ENST00000272542.3	SLC20A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 20 (phosphate transporter), member 1
chr7_+_100303676 Show fit	22.36	ENST00000303151.4	POP7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr22_-_30987849 Show fit	22.35	ENST00000402284.3 ENST00000354694.7	PES1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pescadillo ribosomal biogenesis factor 1
chr11_+_60609537 Show fit	22.34	ENST00000227520.5	CCDC86 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 86
chr10_-_103543145 Show fit	22.24	ENST00000370110.5	NPM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleophosmin/nucleoplasmin 3
chr11_-_118927816 Show fit	22.03	ENST00000534233.1 ENST00000532752.1 ENST00000525859.1 ENST00000404233.3 ENST00000532421.1 ENST00000543287.1 ENST00000527310.2 ENST00000529972.1	HYOU1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hypoxia up-regulated 1
chr5_+_95066823 Show fit	21.63	ENST00000506817.1 ENST00000379982.3	RHOBTB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho-related BTB domain containing 3
chr6_-_114292449 Show fit	21.59	ENST00000519065.1	HDAC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histone deacetylase 2
chr11_+_69455855 Show fit	21.55	ENST00000227507.2 ENST00000536559.1	CCND1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin D1
chr12_-_21810726 Show fit	21.53	ENST00000396076.1	LDHB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lactate dehydrogenase B
chr2_+_118572226 Show fit	21.44	ENST00000263239.2	DDX18 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr8_+_126442563 Show fit	21.25	ENST00000311922.3	TRIB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tribbles pseudokinase 1
chr1_-_86174065 Show fit	20.96	ENST00000370574.3 ENST00000431532.2	ZNHIT6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger, HIT-type containing 6
chr6_+_44191507 Show fit	20.91	ENST00000371724.1 ENST00000371713.1	SLC29A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr1_+_230202936 Show fit	20.91	ENST00000366672.4	GALNT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr2_-_179315453 Show fit	20.85	ENST00000432031.2	PRKRA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase, interferon-inducible double stranded RNA dependent activator
chr12_-_21810765 Show fit	20.77	ENST00000450584.1 ENST00000350669.1	LDHB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lactate dehydrogenase B
chr19_-_14628645 Show fit	20.57	ENST00000598235.1	DNAJB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DnaJ (Hsp40) homolog, subfamily B, member 1
chr5_-_176943917 Show fit	20.47	ENST00000330503.7	DDX41 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
chr3_+_38179969 Show fit	20.43	ENST00000396334.3 ENST00000417037.2 ENST00000424893.1 ENST00000495303.1 ENST00000443433.2 ENST00000421516.1	MYD88 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myeloid differentiation primary response 88
chr6_-_17706618 Show fit	20.30	ENST00000262077.2 ENST00000537253.1	NUP153 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 153kDa
chr15_-_65281775 Show fit	19.89	ENST00000433215.2 ENST00000558415.1 ENST00000557795.1	SPG21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr3_-_149688502 Show fit	19.87	ENST00000481767.1 ENST00000475518.1	PFN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	profilin 2
chr12_-_106641728 Show fit	19.85	ENST00000378026.4	CKAP4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytoskeleton-associated protein 4
chr5_+_138609782 Show fit	19.85	ENST00000361059.2 ENST00000514694.1 ENST00000504203.1 ENST00000502929.1 ENST00000394800.2 ENST00000509644.1 ENST00000505016.1	MATR3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	matrin 3
chr16_-_88851618 Show fit	19.72	ENST00000301015.9	PIEZO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	piezo-type mechanosensitive ion channel component 1
chr2_-_98612350 Show fit	19.53	ENST00000186436.5	TMEM131 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 131
chr12_+_3069037 Show fit	19.25	ENST00000397122.2	TEAD4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TEA domain family member 4
chr1_+_193091080 Show fit	19.21	ENST00000367435.3	CDC73 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle 73
chr3_+_100428268 Show fit	18.94	ENST00000240851.4	TFG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TRK-fused gene
chr3_+_133292574 Show fit	18.93	ENST00000264993.3	CDV3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CDV3 homolog (mouse)
chr3_+_100428316 Show fit	18.88	ENST00000479672.1 ENST00000476228.1 ENST00000463568.1	TFG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TRK-fused gene
chr6_-_33385854 Show fit	18.83	ENST00000488478.1	CUTA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr2_+_48010312 Show fit	18.75	ENST00000540021.1	MSH6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mutS homolog 6
chr22_-_30987837 Show fit	18.58	ENST00000335214.6	PES1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pescadillo ribosomal biogenesis factor 1
chr3_+_100428188 Show fit	18.50	ENST00000418917.2 ENST00000490574.1	TFG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TRK-fused gene
chr12_+_57623477 Show fit	18.48	ENST00000557487.1 ENST00000555634.1 ENST00000556689.1	SHMT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine hydroxymethyltransferase 2 (mitochondrial)
chr2_+_75061108 Show fit	18.47	ENST00000290573.2	HK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hexokinase 2
chr1_+_100436065 Show fit	18.33	ENST00000370153.1	SLC35A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr3_+_25831567 Show fit	18.25	ENST00000280701.3 ENST00000420173.2	OXSM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	3-oxoacyl-ACP synthase, mitochondrial
chr6_+_30539153 Show fit	18.19	ENST00000326195.8 ENST00000376545.3 ENST00000396515.4 ENST00000441867.1 ENST00000468958.1	ABCF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP-binding cassette, sub-family F (GCN20), member 1
chr19_+_1407517 Show fit	17.98	ENST00000336761.6 ENST00000233078.4	DAZAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DAZ associated protein 1
chr22_+_42017123 Show fit	17.81	ENST00000360079.3	XRCC6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	X-ray repair complementing defective repair in Chinese hamster cells 6
chr15_+_96875657 Show fit	17.75	ENST00000559679.1 ENST00000394171.2	NR2F2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 2, group F, member 2
chr11_+_125462690 Show fit	17.72	ENST00000392708.4 ENST00000529196.1 ENST00000531491.1	STT3A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr1_+_214454492 Show fit	17.70	ENST00000366957.5 ENST00000415093.2	SMYD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SET and MYND domain containing 2
chr19_-_29704448 Show fit	17.69	ENST00000304863.4	UQCRFS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr4_-_39529180 Show fit	17.54	ENST00000515021.1 ENST00000510490.1 ENST00000316423.6	UGDH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UDP-glucose 6-dehydrogenase
chr19_+_17622415 Show fit	17.38	ENST00000252603.2 ENST00000600923.1	PGLS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	6-phosphogluconolactonase
chr3_-_50329990 Show fit	17.30	ENST00000417626.2	IFRD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon-related developmental regulator 2
chr2_+_198365095 Show fit	17.20	ENST00000409468.1	HSPE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock 10kDa protein 1
chr11_+_6624970 Show fit	17.11	ENST00000420936.2 ENST00000528995.1	ILK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin-linked kinase
chr1_+_26496362 Show fit	16.97	ENST00000374266.5 ENST00000270812.5	ZNF593 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 593
chr1_-_87379785 Show fit	16.85	ENST00000401030.3 ENST00000370554.1	SEP15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr11_+_6624955 Show fit	16.82	ENST00000299421.4 ENST00000537806.1	ILK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin-linked kinase
chr6_+_44191290 Show fit	16.80	ENST00000371755.3 ENST00000371740.5 ENST00000371731.1 ENST00000393841.1	SLC29A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr11_+_66406088 Show fit	16.78	ENST00000310092.7 ENST00000396053.4 ENST00000408993.2	RBM4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif protein 4
chr2_+_187350973 Show fit	16.77	ENST00000544130.1	ZC3H15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger CCCH-type containing 15
chr9_+_2622085 Show fit	16.72	ENST00000382099.2	VLDLR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	very low density lipoprotein receptor
chr1_-_6259641 Show fit	16.65	ENST00000234875.4	RPL22 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L22
chr6_+_64281906 Show fit	16.60	ENST00000370651.3	PTP4A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase type IVA, member 1
chr16_+_447209 Show fit	16.58	ENST00000382940.4 ENST00000219479.2	NME4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NME/NM23 nucleoside diphosphate kinase 4
chr7_-_105925558 Show fit	16.48	ENST00000222553.3	NAMPT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nicotinamide phosphoribosyltransferase
chr11_+_6625046 Show fit	16.24	ENST00000396751.2	ILK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin-linked kinase
chr10_+_26986582 Show fit	16.20	ENST00000376215.5 ENST00000376203.5	PDSS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prenyl (decaprenyl) diphosphate synthase, subunit 1
chr22_+_42017280 Show fit	15.96	ENST00000402580.3 ENST00000428575.2 ENST00000359308.4	XRCC6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	X-ray repair complementing defective repair in Chinese hamster cells 6
chr17_-_882966 Show fit	15.49	ENST00000336868.3	NXN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoredoxin
chr1_+_214776516 Show fit	15.42	ENST00000366955.3	CENPF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	centromere protein F, 350/400kDa
chr1_-_246729544 Show fit	15.40	ENST00000544618.1 ENST00000366514.4	TFB2M Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor B2, mitochondrial
chr17_-_73179046 Show fit	15.33	ENST00000314523.7 ENST00000420826.2	SUMO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small ubiquitin-like modifier 2
chr5_+_134094461 Show fit	15.19	ENST00000452510.2 ENST00000354283.4	DDX46 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr6_-_153304148 Show fit	15.11	ENST00000229758.3	FBXO5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	F-box protein 5
chr6_-_160210604 Show fit	15.08	ENST00000420894.2 ENST00000539756.1 ENST00000544255.1	TCP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	t-complex 1
chr10_-_16859361 Show fit	14.95	ENST00000377921.3	RSU1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Ras suppressor protein 1

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
29.6	148.0	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
25.5	153.3	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
21.5	86.0	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
21.1	84.6	GO:0046452	dihydrofolate metabolic process(GO:0046452)
20.9	146.3	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
19.9	99.7	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
19.9	99.6	GO:1904637	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
16.5	99.1	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
12.5	25.0	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
12.0	47.8	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
11.0	22.0	GO:1990144	intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
11.0	33.0	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
10.7	224.4	GO:0031639	plasminogen activation(GO:0031639)
10.3	41.2	GO:1901165	negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of trophoblast cell migration(GO:1901165)
10.2	152.9	GO:0006089	lactate metabolic process(GO:0006089)
9.9	29.7	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
9.5	37.9	GO:0090402	oncogene-induced cell senescence(GO:0090402)
9.2	46.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
9.1	54.8	GO:0006177	GMP biosynthetic process(GO:0006177)
8.8	52.5	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
8.4	25.3	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
8.0	48.3	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
8.0	95.7	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
7.8	39.1	GO:1902904	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
7.8	46.6	GO:0048254	snoRNA localization(GO:0048254)
7.7	23.2	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
7.7	23.2	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
7.7	23.1	GO:0006059	hexitol metabolic process(GO:0006059)
7.7	38.4	GO:0010286	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
7.6	22.8	GO:0042450	arginine biosynthetic process via ornithine(GO:0042450)
7.5	37.7	GO:0015862	uridine transport(GO:0015862)
7.3	58.8	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
7.3	22.0	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
7.3	36.5	GO:0061198	fungiform papilla formation(GO:0061198)
7.1	21.2	GO:0045659	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
7.1	56.5	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
6.8	20.3	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
6.5	71.5	GO:0006621	protein retention in ER lumen(GO:0006621)
6.4	12.9	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
6.2	24.9	GO:0002840	plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
6.2	24.8	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
6.2	117.0	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
5.9	17.8	GO:0061073	ciliary body morphogenesis(GO:0061073)
5.9	17.8	GO:1990868	beta selection(GO:0043366) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
5.8	17.4	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
5.4	32.7	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
5.4	21.6	GO:0031860	telomeric 3' overhang formation(GO:0031860)
5.3	101.1	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
5.2	15.6	GO:0021592	fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
5.0	49.5	GO:0007000	nucleolus organization(GO:0007000)
4.9	19.7	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
4.9	24.5	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
4.9	14.7	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
4.8	19.2	GO:1903660	negative regulation of complement-dependent cytotoxicity(GO:1903660)
4.7	33.2	GO:0035795	negative regulation of mitochondrial membrane permeability(GO:0035795)
4.7	85.1	GO:1904816	positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
4.6	23.0	GO:0002905	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
4.6	22.9	GO:0019348	dolichol metabolic process(GO:0019348)
4.5	31.4	GO:0060699	regulation of endoribonuclease activity(GO:0060699)
4.4	17.8	GO:0009956	radial pattern formation(GO:0009956)
4.3	38.9	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
4.2	20.9	GO:0002378	immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via threonine(GO:0018243)
4.1	28.6	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
4.1	20.4	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
4.0	28.0	GO:0033484	nitric oxide homeostasis(GO:0033484)
4.0	11.9	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
3.8	15.4	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
3.8	11.4	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
3.8	22.6	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
3.7	18.3	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
3.6	29.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
3.5	10.5	GO:1903570	regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
3.4	10.1	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
3.2	12.8	GO:0016334	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
3.1	56.6	GO:0042473	outer ear morphogenesis(GO:0042473)
3.1	21.7	GO:1900045	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
3.1	27.9	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
3.1	21.6	GO:0070141	response to UV-A(GO:0070141)
3.1	43.0	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
3.1	18.3	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
3.0	12.0	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
2.9	28.8	GO:0006294	nucleotide-excision repair, preincision complex assembly(GO:0006294)
2.9	11.5	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
2.8	31.3	GO:0006183	GTP biosynthetic process(GO:0006183)
2.8	14.2	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
2.8	28.0	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
2.8	8.3	GO:0000967	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
2.8	60.9	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779)
2.7	30.1	GO:0035721	intraciliary retrograde transport(GO:0035721) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
2.7	18.7	GO:0000710	meiotic mismatch repair(GO:0000710)
2.7	8.0	GO:2000681	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
2.6	29.1	GO:0045176	apical protein localization(GO:0045176)
2.6	5.3	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512)
2.6	18.5	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
2.6	36.0	GO:2000774	positive regulation of cellular senescence(GO:2000774)
2.5	32.9	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
2.5	7.5	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
2.5	12.6	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
2.5	37.2	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
2.3	20.3	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
2.2	22.4	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
2.2	69.4	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
2.1	12.3	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
1.9	7.7	GO:2000035	regulation of stem cell division(GO:2000035)
1.9	11.4	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
1.8	5.5	GO:1902499	positive regulation of protein autoubiquitination(GO:1902499)
1.8	17.7	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
1.7	6.9	GO:1902462	transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
1.7	51.2	GO:0032288	myelin assembly(GO:0032288)
1.7	138.6	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
1.6	19.2	GO:0001711	endodermal cell fate commitment(GO:0001711)
1.6	9.6	GO:0045903	positive regulation of translational fidelity(GO:0045903)
1.6	15.8	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
1.6	4.7	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
1.5	24.6	GO:0006107	oxaloacetate metabolic process(GO:0006107)
1.5	21.1	GO:0038003	opioid receptor signaling pathway(GO:0038003)
1.5	6.0	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.5	16.5	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
1.5	28.1	GO:0009162	deoxyribonucleoside monophosphate metabolic process(GO:0009162)
1.4	12.3	GO:0006564	L-serine biosynthetic process(GO:0006564)
1.4	15.0	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
1.3	18.0	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.3	5.1	GO:0097368	histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
1.3	17.7	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.2	6.2	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.2	22.4	GO:0001682	tRNA 5'-leader removal(GO:0001682)
1.2	30.7	GO:0000002	mitochondrial genome maintenance(GO:0000002)
1.2	15.9	GO:0040016	embryonic cleavage(GO:0040016)
1.2	4.9	GO:0071638	negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
1.2	15.4	GO:0051382	kinetochore assembly(GO:0051382)
1.2	3.6	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
1.2	5.8	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
1.1	12.2	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
1.1	16.4	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
1.1	102.5	GO:0002181	cytoplasmic translation(GO:0002181)
1.1	6.5	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
1.1	9.7	GO:0006552	leucine catabolic process(GO:0006552)
1.0	46.6	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
1.0	15.7	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
1.0	2.9	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
1.0	35.9	GO:0006409	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
1.0	3.9	GO:0035026	leading edge cell differentiation(GO:0035026)
0.9	6.5	GO:0044800	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.9	3.5	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.9	8.7	GO:0033327	Leydig cell differentiation(GO:0033327)
0.9	4.4	GO:0060356	leucine import(GO:0060356)
0.9	77.5	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.9	14.5	GO:0050872	white fat cell differentiation(GO:0050872)
0.8	5.9	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.8	7.4	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.8	12.6	GO:0009086	methionine biosynthetic process(GO:0009086)
0.8	3.1	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
0.8	8.6	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.8	6.2	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.8	19.4	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.7	16.2	GO:0051290	protein heterotetramerization(GO:0051290)
0.7	60.8	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.7	12.1	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.7	2.7	GO:0042360	vitamin E metabolic process(GO:0042360)
0.7	4.7	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.7	3.9	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.6	5.8	GO:0030656	regulation of vitamin metabolic process(GO:0030656)
0.6	41.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.6	12.4	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.6	5.5	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.6	28.9	GO:0031529	ruffle organization(GO:0031529)
0.6	17.4	GO:0009303	rRNA transcription(GO:0009303)
0.6	30.8	GO:0035904	aorta development(GO:0035904)
0.6	18.0	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.5	51.9	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
0.5	37.2	GO:0045454	cell redox homeostasis(GO:0045454)
0.5	3.6	GO:0008090	retrograde axonal transport(GO:0008090)
0.5	2.0	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.5	7.6	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.5	2.5	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.5	21.4	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.5	34.1	GO:0070125	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.5	1.4	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.5	1.4	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.5	80.8	GO:0002576	platelet degranulation(GO:0002576)
0.4	12.6	GO:0043968	histone H2A acetylation(GO:0043968)
0.4	6.6	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.4	12.2	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.4	9.2	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.4	17.7	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.4	7.9	GO:0030252	growth hormone secretion(GO:0030252)
0.4	5.9	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.4	5.5	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.4	26.9	GO:0006364	rRNA processing(GO:0006364)
0.3	6.4	GO:0017145	stem cell division(GO:0017145)
0.3	2.6	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.3	3.5	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.3	0.9	GO:0043105	regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.3	57.5	GO:0008360	regulation of cell shape(GO:0008360)
0.3	16.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.3	10.6	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.3	1.7	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.2	19.0	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2	2.4	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2	1.2	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.2	3.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.2	2.3	GO:0000733	DNA strand renaturation(GO:0000733)
0.2	6.5	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.2	16.8	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.2	11.1	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2	2.1	GO:0045008	depyrimidination(GO:0045008)
0.2	0.8	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.2	5.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.2	6.9	GO:0006270	DNA replication initiation(GO:0006270)
0.2	10.4	GO:0006611	protein export from nucleus(GO:0006611)
0.2	0.9	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.2	5.2	GO:0050900	leukocyte migration(GO:0050900)
0.2	1.5	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.2	5.9	GO:0032456	endocytic recycling(GO:0032456)
0.2	8.1	GO:0051865	protein autoubiquitination(GO:0051865)
0.2	28.1	GO:0007018	microtubule-based movement(GO:0007018)
0.1	0.9	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1	0.3	GO:2001236	regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.1	9.1	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.1	5.0	GO:0006730	one-carbon metabolic process(GO:0006730)
0.1	5.8	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1	3.8	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1	5.1	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.1	0.3	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.1	1.3	GO:0039703	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1	3.1	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	5.0	GO:0006801	superoxide metabolic process(GO:0006801)
0.1	0.4	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1	4.6	GO:0008283	cell proliferation(GO:0008283)
0.1	4.4	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1	0.9	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.1	5.4	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.1	0.5	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1	1.6	GO:0018146	keratan sulfate biosynthetic process(GO:0018146)
0.1	0.9	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	2.1	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	2.9	GO:0009301	snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0	32.7	GO:0045087	innate immune response(GO:0045087)
0.0	3.5	GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0	4.3	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
20.7	124.2	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
16.6	99.6	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
9.7	48.3	GO:0043564	Ku70:Ku80 complex(GO:0043564)
9.3	167.5	GO:0034709	methylosome(GO:0034709)
9.2	46.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
9.0	117.0	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
8.5	25.6	GO:0031428	box C/D snoRNP complex(GO:0031428)
8.2	24.5	GO:0005960	glycine cleavage complex(GO:0005960)
7.2	28.8	GO:0070985	TFIIK complex(GO:0070985)
6.8	40.9	GO:0070545	PeBoW complex(GO:0070545)
6.3	31.6	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
5.6	39.1	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
5.3	63.3	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
4.8	19.2	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
4.7	14.2	GO:0044393	microspike(GO:0044393)
4.7	18.7	GO:0032301	MutSalpha complex(GO:0032301)
4.4	84.4	GO:0036020	endolysosome membrane(GO:0036020)
4.4	44.2	GO:0030126	COPI vesicle coat(GO:0030126)
4.3	106.3	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
4.2	8.3	GO:0030689	Noc complex(GO:0030689)
3.9	23.6	GO:0008537	proteasome activator complex(GO:0008537)
3.9	97.0	GO:0030687	preribosome, large subunit precursor(GO:0030687)
3.9	23.2	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
3.9	170.0	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
3.4	37.9	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
3.3	46.4	GO:0070578	RISC-loading complex(GO:0070578)
3.2	22.4	GO:0000172	ribonuclease MRP complex(GO:0000172)
3.1	15.6	GO:0097513	myosin II filament(GO:0097513)
3.1	21.6	GO:0030870	Mre11 complex(GO:0030870)
3.0	56.2	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
2.9	20.3	GO:0097452	GAIT complex(GO:0097452)
2.9	74.9	GO:0035098	ESC/E(Z) complex(GO:0035098)
2.8	52.5	GO:0005832	chaperonin-containing T-complex(GO:0005832)
2.6	15.8	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
2.6	21.0	GO:0070761	pre-snoRNP complex(GO:0070761)
2.6	12.8	GO:0042643	actomyosin, actin portion(GO:0042643)
2.5	30.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
2.4	55.4	GO:0032156	septin cytoskeleton(GO:0032156)
2.3	18.5	GO:0070552	BRISC complex(GO:0070552)
2.2	31.4	GO:0031616	spindle pole centrosome(GO:0031616)
2.1	30.1	GO:0090543	Flemming body(GO:0090543)
2.1	66.6	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
2.0	32.6	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
1.9	9.7	GO:1905202	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
1.9	19.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
1.9	9.6	GO:0034457	Mpp10 complex(GO:0034457)
1.9	13.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
1.8	14.5	GO:0097470	ribbon synapse(GO:0097470)
1.8	33.7	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
1.7	20.3	GO:0044615	nuclear pore nuclear basket(GO:0044615)
1.6	64.9	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
1.6	17.7	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
1.5	27.7	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
1.4	5.5	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
1.3	9.2	GO:0016272	prefoldin complex(GO:0016272)
1.3	62.5	GO:1904115	axon cytoplasm(GO:1904115)
1.3	5.1	GO:0036449	microtubule minus-end(GO:0036449)
1.2	33.0	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
1.2	25.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
1.1	38.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
1.1	102.6	GO:0043195	terminal bouton(GO:0043195)
1.1	6.6	GO:0000835	ER ubiquitin ligase complex(GO:0000835)
1.1	14.4	GO:0031088	platelet dense granule membrane(GO:0031088)
1.1	16.5	GO:0005686	U2 snRNP(GO:0005686)
1.1	11.9	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
1.0	19.9	GO:0042599	lamellar body(GO:0042599)
1.0	12.2	GO:0042575	DNA polymerase complex(GO:0042575)
1.0	8.0	GO:0034719	SMN-Sm protein complex(GO:0034719) Gemini of coiled bodies(GO:0097504)
1.0	49.1	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.0	64.5	GO:0005637	nuclear inner membrane(GO:0005637)
1.0	17.3	GO:0005685	U1 snRNP(GO:0005685)
1.0	8.6	GO:0072546	ER membrane protein complex(GO:0072546)
0.9	4.7	GO:0070826	paraferritin complex(GO:0070826)
0.9	93.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.9	12.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.8	24.8	GO:0000421	autophagosome membrane(GO:0000421)
0.8	14.7	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.7	135.4	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.7	30.1	GO:0097542	ciliary tip(GO:0097542)
0.6	119.7	GO:0043209	myelin sheath(GO:0043209)
0.6	71.5	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.5	16.7	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.5	4.3	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.5	39.2	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.5	19.7	GO:0031258	lamellipodium membrane(GO:0031258)
0.4	10.3	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.4	24.4	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.4	6.8	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.4	2.4	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.4	12.6	GO:1902562	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.4	36.6	GO:0005643	nuclear pore(GO:0005643)
0.4	5.0	GO:0031528	microvillus membrane(GO:0031528)
0.4	57.6	GO:0016324	apical plasma membrane(GO:0016324)
0.4	6.5	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.3	14.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.3	3.8	GO:0030686	90S preribosome(GO:0030686)
0.3	43.6	GO:0016605	PML body(GO:0016605)
0.3	119.2	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.3	52.8	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.3	34.6	GO:0005604	basement membrane(GO:0005604)
0.3	4.4	GO:0001891	phagocytic cup(GO:0001891)
0.3	12.7	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3	5.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3	2.1	GO:0031931	TORC1 complex(GO:0031931)
0.3	10.4	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.3	10.9	GO:0030175	filopodium(GO:0030175)
0.3	10.5	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.3	5.2	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.2	5.9	GO:0035869	ciliary transition zone(GO:0035869)
0.2	23.1	GO:0031514	motile cilium(GO:0031514)
0.2	1.4	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.2	6.6	GO:0005581	collagen trimer(GO:0005581)
0.2	4.7	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.2	174.4	GO:0005730	nucleolus(GO:0005730)
0.2	506.1	GO:0070062	extracellular exosome(GO:0070062)
0.2	3.9	GO:0002102	podosome(GO:0002102)
0.2	0.5	GO:0000137	Golgi cis cisterna(GO:0000137)
0.2	2.0	GO:0031082	BLOC complex(GO:0031082)
0.2	5.9	GO:0045177	apical part of cell(GO:0045177)
0.1	10.6	GO:0005840	ribosome(GO:0005840)
0.1	7.7	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.1	1.9	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	3.7	GO:0034707	chloride channel complex(GO:0034707)
0.1	5.3	GO:0043204	perikaryon(GO:0043204)
0.1	0.4	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.4	GO:0030054	cell junction(GO:0030054)
0.0	2.3	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	0.9	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
74.8	224.4	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
39.0	117.0	GO:0072510	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
25.9	155.2	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
24.8	99.1	GO:0031871	proteinase activated receptor binding(GO:0031871)
21.3	63.9	GO:0033149	FFAT motif binding(GO:0033149)
20.7	124.2	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
18.5	148.0	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
17.0	68.0	GO:0005046	KDEL sequence binding(GO:0005046)
16.9	118.4	GO:0004457	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
16.2	97.4	GO:0019238	cyclohydrolase activity(GO:0019238)
13.7	41.2	GO:0030984	kininogen binding(GO:0030984)
13.7	54.8	GO:0003938	IMP dehydrogenase activity(GO:0003938)
11.0	33.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
9.7	48.3	GO:0043023	ribosomal large subunit binding(GO:0043023)
9.3	37.4	GO:0071987	WD40-repeat domain binding(GO:0071987)
8.5	76.5	GO:0070883	pre-miRNA binding(GO:0070883)
7.7	23.2	GO:0070361	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
7.6	22.9	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
7.1	35.5	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
6.6	32.9	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
6.5	25.9	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
6.4	19.2	GO:0001884	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
6.1	24.5	GO:0004047	aminomethyltransferase activity(GO:0004047)
5.8	17.4	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
5.6	22.4	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
5.5	16.5	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
5.4	32.7	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
5.1	20.3	GO:0019828	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
4.8	48.3	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
4.7	18.7	GO:0032143	single thymine insertion binding(GO:0032143)
4.5	13.4	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
4.2	16.7	GO:0038025	glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
4.2	24.9	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
3.9	11.8	GO:0032557	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) pyrimidine ribonucleotide binding(GO:0032557) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
3.8	23.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
3.8	84.4	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
3.8	22.6	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
3.7	44.3	GO:0031386	protein tag(GO:0031386)
3.7	22.0	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
3.7	18.3	GO:0004312	fatty acid synthase activity(GO:0004312)
3.6	14.4	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
3.6	39.1	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
3.6	21.3	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
3.5	31.8	GO:0043426	MRF binding(GO:0043426)
3.5	31.3	GO:1901612	cardiolipin binding(GO:1901612)
3.4	23.6	GO:0061133	endopeptidase activator activity(GO:0061133)
3.3	19.7	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
3.2	35.5	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
3.1	46.6	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
3.1	15.5	GO:0047134	protein-disulfide reductase activity(GO:0047134)
3.1	126.7	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
3.1	15.4	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
3.0	142.6	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
3.0	48.4	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
3.0	66.6	GO:0042609	CD4 receptor binding(GO:0042609)
2.9	40.0	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
2.8	22.8	GO:0016842	amidine-lyase activity(GO:0016842)
2.8	79.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
2.8	19.4	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
2.7	124.6	GO:0003785	actin monomer binding(GO:0003785)
2.7	37.7	GO:0008097	5S rRNA binding(GO:0008097)
2.6	18.5	GO:0004793	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
2.6	36.5	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
2.5	17.7	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
2.5	7.5	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)
2.5	17.3	GO:0035614	snRNA stem-loop binding(GO:0035614)
2.5	12.3	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
2.4	46.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
2.3	18.5	GO:0004340	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
2.3	119.9	GO:0016831	carboxy-lyase activity(GO:0016831)
2.3	18.3	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
2.3	11.4	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
2.2	18.0	GO:0035613	RNA stem-loop binding(GO:0035613)
2.2	67.3	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
2.1	6.4	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
2.1	14.5	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
2.0	6.0	GO:0097158	pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
2.0	7.9	GO:0051920	peroxiredoxin activity(GO:0051920)
2.0	17.7	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
2.0	43.2	GO:0004707	MAP kinase activity(GO:0004707)
1.9	9.7	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
1.9	5.8	GO:0015235	cobalamin transporter activity(GO:0015235)
1.9	15.4	GO:0070840	dynein complex binding(GO:0070840)
1.9	21.2	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
1.9	26.3	GO:0042043	neurexin family protein binding(GO:0042043)
1.8	37.7	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
1.8	17.7	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.8	10.5	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.7	27.9	GO:0008494	translation activator activity(GO:0008494)
1.7	12.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.6	21.1	GO:0004985	opioid receptor activity(GO:0004985)
1.6	28.8	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
1.6	75.3	GO:0051879	Hsp90 protein binding(GO:0051879)
1.6	4.7	GO:0008859	exoribonuclease II activity(GO:0008859)
1.6	21.7	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
1.5	94.9	GO:0005507	copper ion binding(GO:0005507)
1.4	22.4	GO:0004526	ribonuclease P activity(GO:0004526)
1.4	20.9	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
1.4	11.1	GO:0008172	S-methyltransferase activity(GO:0008172)
1.3	11.9	GO:0008312	7S RNA binding(GO:0008312)
1.3	60.3	GO:0019894	kinesin binding(GO:0019894)
1.3	10.3	GO:0090599	alpha-glucosidase activity(GO:0090599)
1.3	22.8	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
1.2	21.2	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
1.2	12.3	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
1.2	49.0	GO:0004407	histone deacetylase activity(GO:0004407)
1.2	63.8	GO:0051287	NAD binding(GO:0051287)
1.2	2.3	GO:0032357	oxidized purine DNA binding(GO:0032357)
1.1	25.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
1.1	20.3	GO:0043495	protein anchor(GO:0043495)
1.1	12.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
1.1	32.6	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.1	22.5	GO:0000339	RNA cap binding(GO:0000339)
1.1	43.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.9	21.6	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.9	5.6	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.9	4.7	GO:0015094	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.9	179.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.9	2.7	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.8	15.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.8	39.5	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.8	3.1	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.8	20.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.8	13.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.8	17.3	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.7	23.5	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.7	19.2	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.7	15.6	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.7	3.5	GO:0046923	ER retention sequence binding(GO:0046923)
0.7	4.0	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.7	6.6	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.7	2.0	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.7	20.4	GO:0005123	death receptor binding(GO:0005123)
0.6	11.5	GO:0008266	poly(U) RNA binding(GO:0008266)
0.6	29.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.6	6.5	GO:0046790	virion binding(GO:0046790)
0.6	13.6	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.6	5.0	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.5	10.4	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.5	5.2	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.5	7.6	GO:0030276	clathrin binding(GO:0030276)
0.5	7.5	GO:0046527	glucosyltransferase activity(GO:0046527)
0.5	15.1	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.5	17.8	GO:0001972	retinoic acid binding(GO:0001972)
0.4	5.4	GO:0048156	tau protein binding(GO:0048156)
0.4	77.8	GO:0005178	integrin binding(GO:0005178)
0.4	4.4	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.4	2.4	GO:0019776	Atg8 ligase activity(GO:0019776)
0.4	1.6	GO:0004461	lactose synthase activity(GO:0004461)
0.4	22.0	GO:0051087	chaperone binding(GO:0051087)
0.4	6.4	GO:0005112	Notch binding(GO:0005112)
0.4	31.5	GO:0051082	unfolded protein binding(GO:0051082)
0.4	22.7	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.4	1.4	GO:0097001	ceramide binding(GO:0097001)
0.4	6.5	GO:0001054	RNA polymerase I activity(GO:0001054)
0.4	6.4	GO:0035497	cAMP response element binding(GO:0035497)
0.3	9.8	GO:0017025	TBP-class protein binding(GO:0017025)
0.3	0.9	GO:0044549	GTP cyclohydrolase binding(GO:0044549)
0.3	12.4	GO:0031491	nucleosome binding(GO:0031491)
0.3	5.9	GO:0043014	alpha-tubulin binding(GO:0043014)
0.3	5.2	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.3	3.0	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.2	2.2	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.2	19.4	GO:0032947	protein complex scaffold(GO:0032947)
0.2	3.0	GO:0008179	adenylate cyclase binding(GO:0008179)
0.2	21.6	GO:0008135	translation factor activity, RNA binding(GO:0008135)
0.2	6.4	GO:0017091	AU-rich element binding(GO:0017091)
0.2	3.6	GO:0019213	deacetylase activity(GO:0019213)
0.2	10.9	GO:0017048	Rho GTPase binding(GO:0017048)
0.2	278.3	GO:0003723	RNA binding(GO:0003723)
0.2	4.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.4	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	3.2	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	0.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	1.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	3.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.1	8.0	GO:0004702	receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1	1.4	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	3.1	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1	10.5	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	7.9	GO:0051015	actin filament binding(GO:0051015)
0.1	5.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	1.5	GO:0000287	magnesium ion binding(GO:0000287)
0.0	1.4	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.9	GO:0015485	cholesterol binding(GO:0015485)
0.0	3.8	GO:0005088	Ras guanyl-nucleotide exchange factor activity(GO:0005088)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.1	109.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
5.4	644.9	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
4.4	105.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
3.2	246.8	PID ILK PATHWAY	Integrin-linked kinase signaling
1.9	63.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
1.8	198.2	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
1.8	25.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
1.7	95.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
1.7	48.3	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
1.3	63.8	PID PLK1 PATHWAY	PLK1 signaling events
1.1	74.9	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
1.1	28.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
1.0	13.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.8	26.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.8	15.9	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.6	18.8	PID RHOA PATHWAY	RhoA signaling pathway
0.5	11.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.5	21.6	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.5	91.0	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.5	22.7	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.5	22.7	PID IL4 2PATHWAY	IL4-mediated signaling events
0.4	24.8	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.4	16.7	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.4	18.3	PID AP1 PATHWAY	AP-1 transcription factor network
0.3	9.8	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.3	15.8	PID MTOR 4PATHWAY	mTOR signaling pathway
0.3	17.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.3	10.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.3	15.8	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.3	68.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3	12.2	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.3	5.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2	16.6	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.2	14.7	PID SHP2 PATHWAY	SHP2 signaling
0.2	5.2	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.2	12.3	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.2	6.5	PID IL1 PATHWAY	IL1-mediated signaling events
0.2	3.9	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.2	13.9	PID CMYB PATHWAY	C-MYB transcription factor network
0.2	14.5	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	2.5	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	3.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	2.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	4.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	3.1	PID E2F PATHWAY	E2F transcription factor network
0.0	0.9	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	1.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.1	PID GLYPICAN 1PATHWAY	Glypican 1 network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.9	168.4	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
7.6	389.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
5.5	22.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
5.4	5.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
5.1	92.7	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
3.8	84.4	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
3.7	117.0	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
3.5	87.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
3.0	102.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
2.8	78.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
2.8	47.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
2.3	143.4	REACTOME G1 PHASE	Genes involved in G1 Phase
2.3	38.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
2.2	61.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
2.1	41.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
2.0	52.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
2.0	100.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
2.0	88.8	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
1.9	20.4	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
1.8	57.0	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
1.8	51.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
1.7	58.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.6	47.8	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
1.6	56.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
1.5	136.4	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.5	57.3	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
1.3	11.9	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
1.2	24.9	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
1.2	36.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
1.1	19.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
1.1	69.8	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.1	81.0	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
1.0	9.2	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
1.0	3.9	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.9	6.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.9	41.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.9	21.6	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.9	7.7	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.8	26.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.8	150.8	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.8	20.3	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.7	5.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.7	53.3	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.6	10.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.6	10.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.6	5.5	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.6	6.5	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.6	10.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.5	17.8	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.5	6.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.5	19.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.5	20.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.5	12.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.4	41.9	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.4	16.5	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.4	6.7	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.4	11.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.4	9.8	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.4	9.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.3	18.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.3	5.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.3	1.4	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3	16.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	7.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.2	17.7	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.2	24.2	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2	12.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.2	20.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.2	1.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.2	1.4	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	2.7	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	5.4	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.1	0.9	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	2.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	1.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	2.5	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.0	0.4	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	1.7	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors