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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for ATF6
Z-value: 1.22
Motif logo
Transcription factors associated with ATF6
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ATF6
|
ENSG00000118217.5 | activating transcription factor 6 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ATF6 | hg19_v2_chr1_+_161736072_161736093 | 0.37 | 2.3e-08 | Click! |
Activity profile of ATF6 motif
Sorted Z-values of ATF6 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_+_72148614 | 26.21 |
ENST00000261263.3
|
RAB21
|
RAB21, member RAS oncogene family |
| chr19_+_16186903 | 23.32 |
ENST00000588507.1
|
TPM4
|
tropomyosin 4 |
| chrX_-_102941596 | 20.17 |
ENST00000441076.2
ENST00000422355.1 ENST00000442614.1 ENST00000422154.2 ENST00000451301.1 |
MORF4L2
|
mortality factor 4 like 2 |
| chr19_-_48894104 | 19.37 |
ENST00000597017.1
|
KDELR1
|
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 |
| chr2_-_10588630 | 19.11 |
ENST00000234111.4
|
ODC1
|
ornithine decarboxylase 1 |
| chr21_-_38445470 | 19.03 |
ENST00000399098.1
|
PIGP
|
phosphatidylinositol glycan anchor biosynthesis, class P |
| chr1_+_110527308 | 18.48 |
ENST00000369799.5
|
AHCYL1
|
adenosylhomocysteinase-like 1 |
| chr21_-_38445011 | 17.89 |
ENST00000464265.1
ENST00000399102.1 |
PIGP
|
phosphatidylinositol glycan anchor biosynthesis, class P |
| chrX_+_48433326 | 17.55 |
ENST00000376755.1
|
RBM3
|
RNA binding motif (RNP1, RRM) protein 3 |
| chr10_-_120840309 | 17.41 |
ENST00000369144.3
|
EIF3A
|
eukaryotic translation initiation factor 3, subunit A |
| chr11_-_14521379 | 17.14 |
ENST00000249923.3
ENST00000529866.1 ENST00000439561.2 ENST00000534771.1 |
COPB1
|
coatomer protein complex, subunit beta 1 |
| chr17_+_66511540 | 16.90 |
ENST00000588188.2
|
PRKAR1A
|
protein kinase, cAMP-dependent, regulatory, type I, alpha |
| chr19_+_16187085 | 16.85 |
ENST00000300933.4
|
TPM4
|
tropomyosin 4 |
| chr3_+_52740094 | 16.77 |
ENST00000602728.1
|
SPCS1
|
signal peptidase complex subunit 1 homolog (S. cerevisiae) |
| chr9_+_114393634 | 16.75 |
ENST00000556107.1
ENST00000374294.3 |
DNAJC25
DNAJC25-GNG10
|
DnaJ (Hsp40) homolog, subfamily C , member 25 DNAJC25-GNG10 readthrough |
| chr1_+_44440575 | 15.67 |
ENST00000532642.1
ENST00000236067.4 ENST00000471859.2 |
ATP6V0B
|
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b |
| chr8_+_98656336 | 15.62 |
ENST00000336273.3
|
MTDH
|
metadherin |
| chr12_-_56123444 | 15.48 |
ENST00000546457.1
ENST00000549117.1 |
CD63
|
CD63 molecule |
| chr6_+_24775153 | 15.29 |
ENST00000356509.3
ENST00000230056.3 |
GMNN
|
geminin, DNA replication inhibitor |
| chr8_+_61429728 | 15.08 |
ENST00000529579.1
|
RAB2A
|
RAB2A, member RAS oncogene family |
| chr17_-_57184260 | 15.04 |
ENST00000376149.3
ENST00000393066.3 |
TRIM37
|
tripartite motif containing 37 |
| chr1_-_24126023 | 14.93 |
ENST00000429356.1
|
GALE
|
UDP-galactose-4-epimerase |
| chr17_-_57184064 | 14.77 |
ENST00000262294.7
|
TRIM37
|
tripartite motif containing 37 |
| chr6_-_86352982 | 14.73 |
ENST00000369622.3
|
SYNCRIP
|
synaptotagmin binding, cytoplasmic RNA interacting protein |
| chr3_-_57583185 | 14.08 |
ENST00000463880.1
|
ARF4
|
ADP-ribosylation factor 4 |
| chr17_+_18684563 | 14.03 |
ENST00000476139.1
|
TVP23B
|
trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| chr12_-_56709674 | 13.41 |
ENST00000551286.1
ENST00000549318.1 |
CNPY2
RP11-977G19.10
|
canopy FGF signaling regulator 2 Uncharacterized protein |
| chr17_+_49337881 | 13.41 |
ENST00000225298.7
|
UTP18
|
UTP18 small subunit (SSU) processome component homolog (yeast) |
| chr1_+_228270361 | 13.23 |
ENST00000272102.5
ENST00000540651.1 |
ARF1
|
ADP-ribosylation factor 1 |
| chr5_-_131562935 | 13.05 |
ENST00000379104.2
ENST00000379100.2 ENST00000428369.1 |
P4HA2
|
prolyl 4-hydroxylase, alpha polypeptide II |
| chrX_+_102631248 | 12.93 |
ENST00000361298.4
ENST00000372645.3 ENST00000372635.1 |
NGFRAP1
|
nerve growth factor receptor (TNFRSF16) associated protein 1 |
| chr2_+_242254507 | 12.89 |
ENST00000391973.2
|
SEPT2
|
septin 2 |
| chr21_-_38445443 | 12.80 |
ENST00000360525.4
|
PIGP
|
phosphatidylinositol glycan anchor biosynthesis, class P |
| chr1_+_87170577 | 12.60 |
ENST00000482504.1
|
SH3GLB1
|
SH3-domain GRB2-like endophilin B1 |
| chr3_-_57583052 | 12.51 |
ENST00000496292.1
ENST00000489843.1 |
ARF4
|
ADP-ribosylation factor 4 |
| chr11_-_118927816 | 12.49 |
ENST00000534233.1
ENST00000532752.1 ENST00000525859.1 ENST00000404233.3 ENST00000532421.1 ENST00000543287.1 ENST00000527310.2 ENST00000529972.1 |
HYOU1
|
hypoxia up-regulated 1 |
| chr11_+_32112431 | 12.47 |
ENST00000054950.3
|
RCN1
|
reticulocalbin 1, EF-hand calcium binding domain |
| chr21_-_38445297 | 11.84 |
ENST00000430792.1
ENST00000399103.1 |
PIGP
|
phosphatidylinositol glycan anchor biosynthesis, class P |
| chrX_+_102631844 | 11.76 |
ENST00000372634.1
ENST00000299872.7 |
NGFRAP1
|
nerve growth factor receptor (TNFRSF16) associated protein 1 |
| chr3_+_158519654 | 11.74 |
ENST00000415822.2
ENST00000392813.4 ENST00000264266.8 |
MFSD1
|
major facilitator superfamily domain containing 1 |
| chr17_-_15466742 | 11.56 |
ENST00000584811.1
ENST00000419890.2 |
TVP23C
|
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae) |
| chrX_-_100872911 | 11.35 |
ENST00000361910.4
ENST00000539247.1 ENST00000538627.1 |
ARMCX6
|
armadillo repeat containing, X-linked 6 |
| chr7_-_6523755 | 11.31 |
ENST00000436575.1
ENST00000258739.4 |
DAGLB
KDELR2
|
diacylglycerol lipase, beta KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 |
| chr9_+_112542572 | 11.18 |
ENST00000374530.3
|
PALM2-AKAP2
|
PALM2-AKAP2 readthrough |
| chr6_-_86352642 | 11.18 |
ENST00000355238.6
|
SYNCRIP
|
synaptotagmin binding, cytoplasmic RNA interacting protein |
| chr11_+_112097069 | 11.07 |
ENST00000280362.3
ENST00000525803.1 |
PTS
|
6-pyruvoyltetrahydropterin synthase |
| chr21_+_38445539 | 10.96 |
ENST00000418766.1
ENST00000450533.1 ENST00000438055.1 ENST00000355666.1 ENST00000540756.1 ENST00000399010.1 |
TTC3
|
tetratricopeptide repeat domain 3 |
| chr1_+_228270784 | 10.91 |
ENST00000541182.1
|
ARF1
|
ADP-ribosylation factor 1 |
| chr4_-_99850243 | 10.76 |
ENST00000280892.6
ENST00000511644.1 ENST00000504432.1 ENST00000505992.1 |
EIF4E
|
eukaryotic translation initiation factor 4E |
| chr12_-_106641728 | 10.73 |
ENST00000378026.4
|
CKAP4
|
cytoskeleton-associated protein 4 |
| chr3_-_57583130 | 10.67 |
ENST00000303436.6
|
ARF4
|
ADP-ribosylation factor 4 |
| chr17_-_15466850 | 10.64 |
ENST00000438826.3
ENST00000225576.3 ENST00000519970.1 ENST00000518321.1 ENST00000428082.2 ENST00000522212.2 |
TVP23C
TVP23C-CDRT4
|
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae) TVP23C-CDRT4 readthrough |
| chr22_-_39096661 | 10.61 |
ENST00000216039.5
|
JOSD1
|
Josephin domain containing 1 |
| chr16_+_53164833 | 10.55 |
ENST00000564845.1
|
CHD9
|
chromodomain helicase DNA binding protein 9 |
| chr2_-_55276320 | 10.47 |
ENST00000357376.3
|
RTN4
|
reticulon 4 |
| chr3_+_169684553 | 10.41 |
ENST00000337002.4
ENST00000480708.1 |
SEC62
|
SEC62 homolog (S. cerevisiae) |
| chr19_+_2269485 | 10.12 |
ENST00000582888.4
ENST00000602676.2 ENST00000322297.4 ENST00000583542.4 |
OAZ1
|
ornithine decarboxylase antizyme 1 |
| chrX_+_100663243 | 9.94 |
ENST00000316594.5
|
HNRNPH2
|
heterogeneous nuclear ribonucleoprotein H2 (H') |
| chr5_+_122110691 | 9.87 |
ENST00000379516.2
ENST00000505934.1 ENST00000514949.1 |
SNX2
|
sorting nexin 2 |
| chr6_-_128841503 | 9.86 |
ENST00000368215.3
ENST00000532331.1 ENST00000368213.5 ENST00000368207.3 ENST00000525459.1 ENST00000368210.3 ENST00000368226.4 ENST00000368227.3 |
PTPRK
|
protein tyrosine phosphatase, receptor type, K |
| chr1_-_152009460 | 9.73 |
ENST00000271638.2
|
S100A11
|
S100 calcium binding protein A11 |
| chr20_-_5107180 | 9.66 |
ENST00000379160.3
|
PCNA
|
proliferating cell nuclear antigen |
| chr5_+_34656569 | 9.62 |
ENST00000428746.2
|
RAI14
|
retinoic acid induced 14 |
| chr7_+_100464760 | 9.59 |
ENST00000200457.4
|
TRIP6
|
thyroid hormone receptor interactor 6 |
| chr8_+_98656693 | 9.44 |
ENST00000519934.1
|
MTDH
|
metadherin |
| chr11_+_18416133 | 9.43 |
ENST00000227157.4
ENST00000478970.2 ENST00000495052.1 |
LDHA
|
lactate dehydrogenase A |
| chr10_-_104953009 | 9.40 |
ENST00000470299.1
ENST00000343289.5 |
NT5C2
|
5'-nucleotidase, cytosolic II |
| chrX_-_100914781 | 9.34 |
ENST00000431597.1
ENST00000458024.1 ENST00000413506.1 ENST00000440675.1 ENST00000328766.5 ENST00000356824.4 |
ARMCX2
|
armadillo repeat containing, X-linked 2 |
| chr8_+_109455845 | 9.32 |
ENST00000220853.3
|
EMC2
|
ER membrane protein complex subunit 2 |
| chr7_+_128379346 | 9.29 |
ENST00000535011.2
ENST00000542996.2 ENST00000535623.1 ENST00000538546.1 ENST00000249364.4 ENST00000449187.2 |
CALU
|
calumenin |
| chr6_+_116692102 | 9.28 |
ENST00000359564.2
|
DSE
|
dermatan sulfate epimerase |
| chr9_+_100818976 | 9.24 |
ENST00000210444.5
|
NANS
|
N-acetylneuraminic acid synthase |
| chr21_-_46237883 | 9.22 |
ENST00000397893.3
|
SUMO3
|
small ubiquitin-like modifier 3 |
| chr2_+_216176540 | 9.11 |
ENST00000236959.9
|
ATIC
|
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
| chr10_+_121410882 | 9.06 |
ENST00000369085.3
|
BAG3
|
BCL2-associated athanogene 3 |
| chr12_-_102455846 | 8.99 |
ENST00000545679.1
|
CCDC53
|
coiled-coil domain containing 53 |
| chr2_+_242254679 | 8.90 |
ENST00000428282.1
ENST00000360051.3 |
SEPT2
|
septin 2 |
| chr7_-_86849883 | 8.89 |
ENST00000433078.1
|
TMEM243
|
transmembrane protein 243, mitochondrial |
| chr3_+_148709128 | 8.75 |
ENST00000345003.4
ENST00000296048.6 ENST00000483267.1 |
GYG1
|
glycogenin 1 |
| chr1_+_19970657 | 8.69 |
ENST00000375136.3
|
NBL1
|
neuroblastoma 1, DAN family BMP antagonist |
| chr5_-_72744336 | 8.53 |
ENST00000499003.3
|
FOXD1
|
forkhead box D1 |
| chr1_-_211752073 | 8.49 |
ENST00000367001.4
|
SLC30A1
|
solute carrier family 30 (zinc transporter), member 1 |
| chr5_+_34656331 | 8.48 |
ENST00000265109.3
|
RAI14
|
retinoic acid induced 14 |
| chr7_+_5632436 | 8.48 |
ENST00000340250.6
ENST00000382361.3 |
FSCN1
|
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) |
| chr7_+_128379449 | 8.36 |
ENST00000479257.1
|
CALU
|
calumenin |
| chr7_+_16793160 | 8.34 |
ENST00000262067.4
|
TSPAN13
|
tetraspanin 13 |
| chr12_-_76953573 | 8.24 |
ENST00000549646.1
ENST00000550628.1 ENST00000553139.1 ENST00000261183.3 ENST00000393250.4 |
OSBPL8
|
oxysterol binding protein-like 8 |
| chr3_-_129158850 | 8.18 |
ENST00000503197.1
ENST00000249910.1 ENST00000429544.2 ENST00000507208.1 |
MBD4
|
methyl-CpG binding domain protein 4 |
| chr7_+_12726474 | 8.18 |
ENST00000396662.1
ENST00000356797.3 ENST00000396664.2 |
ARL4A
|
ADP-ribosylation factor-like 4A |
| chr9_+_101984577 | 8.06 |
ENST00000223641.4
|
SEC61B
|
Sec61 beta subunit |
| chr1_-_1822495 | 7.98 |
ENST00000378609.4
|
GNB1
|
guanine nucleotide binding protein (G protein), beta polypeptide 1 |
| chr17_+_37026284 | 7.95 |
ENST00000433206.2
ENST00000435347.3 |
LASP1
|
LIM and SH3 protein 1 |
| chr2_-_242212227 | 7.92 |
ENST00000427007.1
ENST00000458564.1 ENST00000452065.1 ENST00000427183.2 ENST00000426343.1 ENST00000422080.1 ENST00000449504.1 ENST00000449864.1 ENST00000391975.1 |
HDLBP
|
high density lipoprotein binding protein |
| chr21_-_46238034 | 7.91 |
ENST00000332859.6
|
SUMO3
|
small ubiquitin-like modifier 3 |
| chr11_-_77790865 | 7.87 |
ENST00000534029.1
ENST00000525085.1 ENST00000527806.1 ENST00000528164.1 ENST00000528251.1 ENST00000530054.1 |
NDUFC2
NDUFC2-KCTD14
|
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa NDUFC2-KCTD14 readthrough |
| chr7_+_26240776 | 7.86 |
ENST00000337620.4
|
CBX3
|
chromobox homolog 3 |
| chr2_+_216176761 | 7.84 |
ENST00000540518.1
ENST00000435675.1 |
ATIC
|
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
| chr17_+_37026106 | 7.80 |
ENST00000318008.6
|
LASP1
|
LIM and SH3 protein 1 |
| chr8_-_17104356 | 7.80 |
ENST00000361272.4
ENST00000523917.1 |
CNOT7
|
CCR4-NOT transcription complex, subunit 7 |
| chr19_+_50354393 | 7.72 |
ENST00000391842.1
|
PTOV1
|
prostate tumor overexpressed 1 |
| chr6_-_3157760 | 7.61 |
ENST00000333628.3
|
TUBB2A
|
tubulin, beta 2A class IIa |
| chrX_+_153672468 | 7.59 |
ENST00000393600.3
|
FAM50A
|
family with sequence similarity 50, member A |
| chr4_+_17616253 | 7.58 |
ENST00000237380.7
|
MED28
|
mediator complex subunit 28 |
| chr1_-_193028632 | 7.44 |
ENST00000421683.1
|
UCHL5
|
ubiquitin carboxyl-terminal hydrolase L5 |
| chr1_+_19970797 | 7.19 |
ENST00000548815.1
|
NBL1
|
neuroblastoma 1, DAN family BMP antagonist |
| chr5_+_65440032 | 7.19 |
ENST00000334121.6
|
SREK1
|
splicing regulatory glutamine/lysine-rich protein 1 |
| chr18_+_12703002 | 7.18 |
ENST00000590217.1
|
PSMG2
|
proteasome (prosome, macropain) assembly chaperone 2 |
| chr19_+_50354462 | 7.15 |
ENST00000601675.1
|
PTOV1
|
prostate tumor overexpressed 1 |
| chr7_-_26240357 | 7.15 |
ENST00000354667.4
ENST00000356674.7 |
HNRNPA2B1
|
heterogeneous nuclear ribonucleoprotein A2/B1 |
| chr5_-_131563501 | 7.11 |
ENST00000401867.1
ENST00000379086.1 ENST00000418055.1 ENST00000453286.1 ENST00000166534.4 |
P4HA2
|
prolyl 4-hydroxylase, alpha polypeptide II |
| chr14_-_50087312 | 7.04 |
ENST00000298289.6
|
RPL36AL
|
ribosomal protein L36a-like |
| chr12_-_102455902 | 7.03 |
ENST00000240079.6
|
CCDC53
|
coiled-coil domain containing 53 |
| chr2_+_201754050 | 6.98 |
ENST00000426253.1
ENST00000416651.1 ENST00000454952.1 ENST00000409020.1 ENST00000359683.4 |
NIF3L1
|
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) |
| chr1_-_193028621 | 6.96 |
ENST00000367455.4
ENST00000367454.1 |
UCHL5
|
ubiquitin carboxyl-terminal hydrolase L5 |
| chr14_+_55518349 | 6.93 |
ENST00000395468.4
|
MAPK1IP1L
|
mitogen-activated protein kinase 1 interacting protein 1-like |
| chr16_-_69373396 | 6.91 |
ENST00000562595.1
ENST00000562081.1 ENST00000306875.4 |
COG8
|
component of oligomeric golgi complex 8 |
| chr1_-_51425902 | 6.88 |
ENST00000396153.2
|
FAF1
|
Fas (TNFRSF6) associated factor 1 |
| chr2_-_98612350 | 6.88 |
ENST00000186436.5
|
TMEM131
|
transmembrane protein 131 |
| chr10_-_74856608 | 6.84 |
ENST00000307116.2
ENST00000373008.2 ENST00000412021.2 ENST00000394890.2 ENST00000263556.3 ENST00000440381.1 |
P4HA1
|
prolyl 4-hydroxylase, alpha polypeptide I |
| chr12_-_49412541 | 6.82 |
ENST00000547306.1
ENST00000548857.1 ENST00000551696.1 ENST00000316299.5 |
PRKAG1
|
protein kinase, AMP-activated, gamma 1 non-catalytic subunit |
| chr21_-_46237959 | 6.79 |
ENST00000397898.3
ENST00000411651.2 |
SUMO3
|
small ubiquitin-like modifier 3 |
| chr15_+_96869165 | 6.69 |
ENST00000421109.2
|
NR2F2
|
nuclear receptor subfamily 2, group F, member 2 |
| chr17_-_39968406 | 6.64 |
ENST00000393928.1
|
LEPREL4
|
leprecan-like 4 |
| chr12_-_49412588 | 6.58 |
ENST00000547082.1
ENST00000395170.3 |
PRKAG1
|
protein kinase, AMP-activated, gamma 1 non-catalytic subunit |
| chr1_+_26798955 | 6.57 |
ENST00000361427.5
|
HMGN2
|
high mobility group nucleosomal binding domain 2 |
| chr17_+_33914460 | 6.51 |
ENST00000537622.2
|
AP2B1
|
adaptor-related protein complex 2, beta 1 subunit |
| chr11_+_118230287 | 6.43 |
ENST00000252108.3
ENST00000431736.2 |
UBE4A
|
ubiquitination factor E4A |
| chr2_+_201754135 | 6.43 |
ENST00000409357.1
ENST00000409129.2 |
NIF3L1
|
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) |
| chr4_-_83350580 | 6.38 |
ENST00000349655.4
ENST00000602300.1 |
HNRNPDL
|
heterogeneous nuclear ribonucleoprotein D-like |
| chr1_+_32645269 | 6.28 |
ENST00000373610.3
|
TXLNA
|
taxilin alpha |
| chr19_+_49375649 | 6.25 |
ENST00000200453.5
|
PPP1R15A
|
protein phosphatase 1, regulatory subunit 15A |
| chr1_+_40505891 | 6.10 |
ENST00000372797.3
ENST00000372802.1 ENST00000449311.1 |
CAP1
|
CAP, adenylate cyclase-associated protein 1 (yeast) |
| chr1_-_43833628 | 6.08 |
ENST00000413844.2
ENST00000372458.3 |
ELOVL1
|
ELOVL fatty acid elongase 1 |
| chrX_-_100662881 | 6.06 |
ENST00000218516.3
|
GLA
|
galactosidase, alpha |
| chr17_+_33914276 | 6.02 |
ENST00000592545.1
ENST00000538556.1 ENST00000312678.8 ENST00000589344.1 |
AP2B1
|
adaptor-related protein complex 2, beta 1 subunit |
| chr1_-_78148324 | 6.02 |
ENST00000370801.3
ENST00000433749.1 |
ZZZ3
|
zinc finger, ZZ-type containing 3 |
| chr2_-_240964716 | 5.97 |
ENST00000404554.1
ENST00000407129.3 ENST00000307300.4 ENST00000443626.1 ENST00000252711.2 |
NDUFA10
|
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa |
| chr17_+_57642886 | 5.94 |
ENST00000251241.4
ENST00000451169.2 ENST00000425628.3 ENST00000584385.1 ENST00000580030.1 |
DHX40
|
DEAH (Asp-Glu-Ala-His) box polypeptide 40 |
| chr19_+_50354430 | 5.93 |
ENST00000599732.1
|
PTOV1
|
prostate tumor overexpressed 1 |
| chr15_-_75230368 | 5.79 |
ENST00000564811.1
ENST00000562233.1 ENST00000567270.1 ENST00000568783.1 |
COX5A
|
cytochrome c oxidase subunit Va |
| chr6_-_32145861 | 5.77 |
ENST00000336984.6
|
AGPAT1
|
1-acylglycerol-3-phosphate O-acyltransferase 1 |
| chr1_-_32801825 | 5.76 |
ENST00000329421.7
|
MARCKSL1
|
MARCKS-like 1 |
| chr4_-_54930790 | 5.75 |
ENST00000263921.3
|
CHIC2
|
cysteine-rich hydrophobic domain 2 |
| chr14_+_20923350 | 5.73 |
ENST00000555414.1
ENST00000216714.3 ENST00000553681.1 ENST00000557344.1 ENST00000398030.4 ENST00000557181.1 ENST00000555839.1 ENST00000553368.1 ENST00000556054.1 ENST00000557054.1 ENST00000557592.1 ENST00000557150.1 |
APEX1
|
APEX nuclease (multifunctional DNA repair enzyme) 1 |
| chr19_-_4670345 | 5.72 |
ENST00000599630.1
ENST00000262947.3 |
C19orf10
|
chromosome 19 open reading frame 10 |
| chr13_+_114238997 | 5.72 |
ENST00000538138.1
ENST00000375370.5 |
TFDP1
|
transcription factor Dp-1 |
| chr3_-_129158676 | 5.71 |
ENST00000393278.2
|
MBD4
|
methyl-CpG binding domain protein 4 |
| chr1_-_94344754 | 5.62 |
ENST00000436063.2
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2 |
| chr11_+_102217936 | 5.59 |
ENST00000532832.1
ENST00000530675.1 ENST00000533742.1 ENST00000227758.2 ENST00000532672.1 ENST00000531259.1 ENST00000527465.1 |
BIRC2
|
baculoviral IAP repeat containing 2 |
| chr4_-_119757239 | 5.55 |
ENST00000280551.6
|
SEC24D
|
SEC24 family member D |
| chr19_-_6502304 | 5.55 |
ENST00000540257.1
ENST00000594276.1 ENST00000594075.1 ENST00000600216.1 ENST00000596926.1 |
TUBB4A
|
tubulin, beta 4A class IVa |
| chr1_-_94050668 | 5.50 |
ENST00000539242.1
|
BCAR3
|
breast cancer anti-estrogen resistance 3 |
| chr15_-_72668805 | 5.43 |
ENST00000268097.5
|
HEXA
|
hexosaminidase A (alpha polypeptide) |
| chr22_+_24236191 | 5.42 |
ENST00000215754.7
|
MIF
|
macrophage migration inhibitory factor (glycosylation-inhibiting factor) |
| chr2_+_242255297 | 5.29 |
ENST00000401990.1
ENST00000407971.1 ENST00000436795.1 ENST00000411484.1 ENST00000434955.1 ENST00000402092.2 ENST00000441533.1 ENST00000443492.1 ENST00000437066.1 ENST00000429791.1 |
SEPT2
|
septin 2 |
| chr16_+_69373661 | 5.26 |
ENST00000254941.6
|
NIP7
|
NIP7, nucleolar pre-rRNA processing protein |
| chr1_-_51425772 | 5.23 |
ENST00000371778.4
|
FAF1
|
Fas (TNFRSF6) associated factor 1 |
| chr3_-_195270162 | 5.14 |
ENST00000438848.1
ENST00000328432.3 |
PPP1R2
|
protein phosphatase 1, regulatory (inhibitor) subunit 2 |
| chr8_+_29953163 | 5.13 |
ENST00000518192.1
|
LEPROTL1
|
leptin receptor overlapping transcript-like 1 |
| chr19_-_6502590 | 5.06 |
ENST00000264071.2
|
TUBB4A
|
tubulin, beta 4A class IVa |
| chr12_-_125398602 | 4.94 |
ENST00000541272.1
ENST00000535131.1 |
UBC
|
ubiquitin C |
| chr8_-_124408652 | 4.91 |
ENST00000287394.5
|
ATAD2
|
ATPase family, AAA domain containing 2 |
| chr3_+_100211412 | 4.87 |
ENST00000323523.4
ENST00000403410.1 ENST00000449609.1 |
TMEM45A
|
transmembrane protein 45A |
| chr20_+_35090150 | 4.72 |
ENST00000340491.4
|
DLGAP4
|
discs, large (Drosophila) homolog-associated protein 4 |
| chr1_-_160313025 | 4.70 |
ENST00000368069.3
ENST00000241704.7 |
COPA
|
coatomer protein complex, subunit alpha |
| chr9_-_74980113 | 4.63 |
ENST00000376962.5
ENST00000376960.4 ENST00000237937.3 |
ZFAND5
|
zinc finger, AN1-type domain 5 |
| chr7_-_99699538 | 4.57 |
ENST00000343023.6
ENST00000303887.5 |
MCM7
|
minichromosome maintenance complex component 7 |
| chr1_-_193028426 | 4.51 |
ENST00000367450.3
ENST00000530098.2 ENST00000367451.4 ENST00000367448.1 ENST00000367449.1 |
UCHL5
|
ubiquitin carboxyl-terminal hydrolase L5 |
| chr6_+_32936353 | 4.49 |
ENST00000374825.4
|
BRD2
|
bromodomain containing 2 |
| chrX_-_102319092 | 4.45 |
ENST00000372728.3
|
BEX1
|
brain expressed, X-linked 1 |
| chr1_+_32645645 | 4.41 |
ENST00000373609.1
|
TXLNA
|
taxilin alpha |
| chr5_+_151151471 | 4.41 |
ENST00000394123.3
ENST00000543466.1 |
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1 |
| chr17_-_39968855 | 4.36 |
ENST00000355468.3
ENST00000590496.1 |
LEPREL4
|
leprecan-like 4 |
| chr17_-_80231557 | 4.28 |
ENST00000392334.2
ENST00000314028.6 |
CSNK1D
|
casein kinase 1, delta |
| chr2_-_242255117 | 4.26 |
ENST00000420451.1
ENST00000417540.1 ENST00000310931.4 |
HDLBP
|
high density lipoprotein binding protein |
| chr5_+_151151504 | 4.19 |
ENST00000356245.3
ENST00000507878.2 |
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1 |
| chr16_-_67514982 | 4.16 |
ENST00000565835.1
ENST00000540149.1 ENST00000290949.3 |
ATP6V0D1
|
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 |
| chr7_+_100860949 | 4.14 |
ENST00000305105.2
|
ZNHIT1
|
zinc finger, HIT-type containing 1 |
| chr16_+_14726672 | 4.13 |
ENST00000261658.2
ENST00000563971.1 |
BFAR
|
bifunctional apoptosis regulator |
| chr12_-_49412525 | 4.07 |
ENST00000551121.1
ENST00000552212.1 ENST00000548605.1 ENST00000548950.1 ENST00000547125.1 |
PRKAG1
|
protein kinase, AMP-activated, gamma 1 non-catalytic subunit |
| chr18_+_9913977 | 3.97 |
ENST00000400000.2
ENST00000340541.4 |
VAPA
|
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa |
| chr12_-_10766184 | 3.91 |
ENST00000539554.1
ENST00000381881.2 ENST00000320756.2 |
MAGOHB
|
mago-nashi homolog B (Drosophila) |
| chr4_-_1242764 | 3.91 |
ENST00000514210.1
ENST00000382952.3 ENST00000290921.6 |
CTBP1
|
C-terminal binding protein 1 |
| chr12_+_54718904 | 3.90 |
ENST00000262061.2
ENST00000549043.1 ENST00000552218.1 ENST00000553231.1 ENST00000552362.1 ENST00000455864.2 ENST00000416254.2 ENST00000549116.1 ENST00000551779.1 |
COPZ1
|
coatomer protein complex, subunit zeta 1 |
| chr1_-_78149041 | 3.87 |
ENST00000414381.1
ENST00000370798.1 |
ZZZ3
|
zinc finger, ZZ-type containing 3 |
| chr3_+_183415558 | 3.87 |
ENST00000305135.5
|
YEATS2
|
YEATS domain containing 2 |
| chr8_+_61429416 | 3.83 |
ENST00000262646.7
ENST00000531289.1 |
RAB2A
|
RAB2A, member RAS oncogene family |
| chr22_+_38864041 | 3.80 |
ENST00000216014.4
ENST00000409006.3 |
KDELR3
|
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| chr19_-_42759300 | 3.66 |
ENST00000222329.4
|
ERF
|
Ets2 repressor factor |
| chr3_+_50284321 | 3.61 |
ENST00000451956.1
|
GNAI2
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| chr8_+_29952914 | 3.58 |
ENST00000321250.8
ENST00000518001.1 ENST00000520682.1 ENST00000442880.2 ENST00000523116.1 |
LEPROTL1
|
leptin receptor overlapping transcript-like 1 |
| chr19_+_50353944 | 3.55 |
ENST00000594151.1
ENST00000600603.1 ENST00000601638.1 ENST00000221557.9 |
PTOV1
|
prostate tumor overexpressed 1 |
| chr3_+_133292574 | 3.48 |
ENST00000264993.3
|
CDV3
|
CDV3 homolog (mouse) |
| chr5_-_94890648 | 3.47 |
ENST00000513823.1
ENST00000514952.1 ENST00000358746.2 |
TTC37
|
tetratricopeptide repeat domain 37 |
| chr14_-_50053081 | 3.47 |
ENST00000396020.3
ENST00000245458.6 |
RPS29
|
ribosomal protein S29 |
| chr3_+_127317066 | 3.38 |
ENST00000265056.7
|
MCM2
|
minichromosome maintenance complex component 2 |
| chr1_+_233749739 | 3.32 |
ENST00000366621.3
|
KCNK1
|
potassium channel, subfamily K, member 1 |
| chr3_-_139108475 | 3.24 |
ENST00000515006.1
ENST00000513274.1 ENST00000514508.1 ENST00000507777.1 ENST00000512153.1 ENST00000333188.5 |
COPB2
|
coatomer protein complex, subunit beta 2 (beta prime) |
| chr12_+_70636765 | 3.22 |
ENST00000552231.1
ENST00000229195.3 ENST00000547780.1 ENST00000418359.3 |
CNOT2
|
CCR4-NOT transcription complex, subunit 2 |
| chr1_+_167691191 | 3.21 |
ENST00000392121.3
ENST00000474859.1 |
MPZL1
|
myelin protein zero-like 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ATF6
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.9 | 29.8 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 8.0 | 24.1 | GO:0097212 | cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822) |
| 5.8 | 17.4 | GO:0002188 | formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188) |
| 5.3 | 15.9 | GO:0038098 | sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 4.8 | 19.1 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
| 4.2 | 17.0 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 4.1 | 4.1 | GO:1903895 | negative regulation of IRE1-mediated unfolded protein response(GO:1903895) |
| 3.7 | 25.9 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 3.7 | 18.5 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 3.4 | 37.3 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 3.2 | 12.6 | GO:1903778 | protein localization to vacuolar membrane(GO:1903778) |
| 3.1 | 34.5 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 3.1 | 61.6 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 2.6 | 18.5 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 2.6 | 26.2 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 2.6 | 15.7 | GO:0071163 | DNA replication preinitiation complex assembly(GO:0071163) |
| 2.5 | 12.5 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 2.4 | 9.7 | GO:1902990 | leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990) |
| 2.1 | 6.2 | GO:1902310 | regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 2.1 | 27.0 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 2.0 | 10.1 | GO:1902267 | polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268) |
| 1.9 | 9.6 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 1.9 | 5.7 | GO:0006286 | base-excision repair, base-free sugar-phosphate removal(GO:0006286) |
| 1.9 | 5.6 | GO:1902523 | positive regulation of protein K63-linked ubiquitination(GO:1902523) |
| 1.8 | 7.1 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 1.7 | 8.5 | GO:0072076 | nephrogenic mesenchyme development(GO:0072076) |
| 1.7 | 6.7 | GO:0009956 | radial pattern formation(GO:0009956) |
| 1.6 | 11.1 | GO:0046146 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 1.5 | 13.4 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 1.5 | 8.7 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 1.4 | 1.4 | GO:1902953 | positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) |
| 1.4 | 8.5 | GO:0030035 | microspike assembly(GO:0030035) |
| 1.3 | 9.4 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 1.3 | 4.0 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
| 1.2 | 12.5 | GO:1903298 | regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) |
| 1.2 | 8.5 | GO:0061687 | detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501) |
| 1.2 | 15.5 | GO:2000680 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 1.2 | 18.9 | GO:0021670 | lateral ventricle development(GO:0021670) |
| 1.2 | 8.2 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 1.2 | 10.5 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 1.2 | 2.3 | GO:2000793 | cell proliferation involved in heart valve development(GO:2000793) |
| 1.1 | 14.9 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 1.1 | 1.1 | GO:1903094 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
| 1.1 | 7.8 | GO:0060339 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) negative regulation of type I interferon-mediated signaling pathway(GO:0060339) |
| 1.1 | 12.2 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 1.1 | 5.4 | GO:0002906 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 1.1 | 13.9 | GO:0045008 | depyrimidination(GO:0045008) |
| 1.1 | 4.2 | GO:0048698 | negative regulation of collateral sprouting in absence of injury(GO:0048698) |
| 1.1 | 16.9 | GO:2000480 | negative regulation of meiotic nuclear division(GO:0045835) negative regulation of activated T cell proliferation(GO:0046007) negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 1.0 | 3.1 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
| 1.0 | 6.1 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 1.0 | 12.1 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.9 | 2.8 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.8 | 2.5 | GO:0061188 | negative regulation of chromatin silencing at rDNA(GO:0061188) |
| 0.8 | 4.9 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.8 | 5.7 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.8 | 7.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.8 | 16.8 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.8 | 6.1 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 0.7 | 9.4 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 0.7 | 9.9 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.7 | 20.0 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.7 | 19.8 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.7 | 7.5 | GO:0030207 | chondroitin sulfate catabolic process(GO:0030207) |
| 0.7 | 3.9 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 0.6 | 3.9 | GO:0071649 | regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651) |
| 0.6 | 11.6 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.6 | 2.5 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
| 0.6 | 29.8 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 0.6 | 32.0 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.6 | 9.1 | GO:0097201 | negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201) |
| 0.6 | 1.7 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 0.5 | 2.2 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.5 | 7.6 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.5 | 3.2 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.5 | 7.2 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.5 | 2.5 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 0.5 | 40.2 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.5 | 10.6 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.5 | 7.6 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.4 | 1.7 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
| 0.4 | 2.1 | GO:0045007 | depurination(GO:0045007) |
| 0.4 | 3.3 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 0.4 | 1.5 | GO:1903803 | glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803) |
| 0.4 | 9.3 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.4 | 1.8 | GO:0014916 | regulation of lung blood pressure(GO:0014916) negative regulation of lung blood pressure(GO:0061767) |
| 0.3 | 3.1 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 0.3 | 13.4 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.3 | 1.0 | GO:0046946 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.3 | 2.0 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.3 | 2.6 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.3 | 22.9 | GO:0031663 | lipopolysaccharide-mediated signaling pathway(GO:0031663) |
| 0.3 | 10.9 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.3 | 1.5 | GO:0042695 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
| 0.3 | 2.0 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.3 | 0.8 | GO:1901143 | insulin catabolic process(GO:1901143) |
| 0.3 | 0.8 | GO:0042450 | arginine biosynthetic process via ornithine(GO:0042450) |
| 0.3 | 5.8 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.3 | 2.3 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.3 | 4.3 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 0.2 | 14.3 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.2 | 1.4 | GO:0021514 | ventral spinal cord interneuron differentiation(GO:0021514) |
| 0.2 | 4.4 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.2 | 3.0 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.2 | 0.9 | GO:1903121 | regulation of ribosome biogenesis(GO:0090069) regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.2 | 8.2 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.2 | 5.7 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.2 | 4.1 | GO:0031063 | regulation of histone deacetylation(GO:0031063) |
| 0.2 | 1.9 | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
| 0.2 | 5.8 | GO:0046718 | viral entry into host cell(GO:0046718) |
| 0.2 | 10.4 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.2 | 2.3 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.2 | 2.9 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.2 | 6.8 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
| 0.2 | 1.0 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.2 | 1.5 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 0.2 | 1.6 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.2 | 3.9 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.2 | 5.8 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.2 | 4.6 | GO:0003016 | respiratory system process(GO:0003016) |
| 0.1 | 4.0 | GO:0033622 | integrin activation(GO:0033622) |
| 0.1 | 1.7 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.1 | 18.5 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.1 | 1.4 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 9.9 | GO:0034394 | protein localization to cell surface(GO:0034394) |
| 0.1 | 5.8 | GO:0001961 | positive regulation of cytokine-mediated signaling pathway(GO:0001961) |
| 0.1 | 7.3 | GO:0042255 | ribosome assembly(GO:0042255) |
| 0.1 | 11.9 | GO:0006110 | regulation of glycolytic process(GO:0006110) |
| 0.1 | 6.6 | GO:0044364 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.1 | 1.3 | GO:1901407 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) |
| 0.1 | 0.8 | GO:0071027 | nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028) |
| 0.1 | 5.1 | GO:0005977 | glycogen metabolic process(GO:0005977) |
| 0.1 | 3.9 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.1 | 2.3 | GO:0042921 | glucocorticoid receptor signaling pathway(GO:0042921) |
| 0.1 | 5.3 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
| 0.1 | 2.7 | GO:0009306 | protein secretion(GO:0009306) |
| 0.1 | 11.8 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.1 | 5.3 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.1 | 4.4 | GO:0070671 | response to interleukin-12(GO:0070671) |
| 0.1 | 6.2 | GO:0007224 | smoothened signaling pathway(GO:0007224) |
| 0.1 | 0.8 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
| 0.0 | 1.2 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 1.1 | GO:0009226 | nucleotide-sugar biosynthetic process(GO:0009226) |
| 0.0 | 1.2 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.0 | 3.3 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 1.0 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 7.2 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 4.4 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
| 0.0 | 2.0 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.0 | 1.2 | GO:0006469 | negative regulation of protein kinase activity(GO:0006469) |
| 0.0 | 3.5 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 3.3 | GO:0006006 | glucose metabolic process(GO:0006006) |
| 0.0 | 0.8 | GO:0018146 | keratan sulfate biosynthetic process(GO:0018146) |
| 0.0 | 0.7 | GO:0048747 | muscle fiber development(GO:0048747) |
| 0.0 | 0.3 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.0 | 0.0 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
| 0.0 | 5.5 | GO:0043312 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.2 | 61.6 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 3.7 | 25.9 | GO:0097452 | GAIT complex(GO:0097452) |
| 3.7 | 51.3 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 3.6 | 25.1 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 3.3 | 26.2 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 3.2 | 9.7 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 2.8 | 8.5 | GO:0044393 | microspike(GO:0044393) |
| 2.7 | 13.4 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 2.4 | 24.1 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 2.4 | 16.8 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 2.3 | 6.8 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 2.1 | 40.2 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 1.9 | 7.8 | GO:0042025 | host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 1.9 | 17.4 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 1.9 | 27.1 | GO:0097227 | sperm annulus(GO:0097227) |
| 1.9 | 9.6 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 1.7 | 15.7 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 1.7 | 34.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 1.6 | 9.9 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 1.6 | 9.8 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 1.6 | 17.6 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 1.5 | 10.6 | GO:0033269 | internode region of axon(GO:0033269) |
| 1.3 | 15.5 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 1.1 | 29.8 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 1.0 | 19.8 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 1.0 | 9.3 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 1.0 | 10.8 | GO:0033391 | chromatoid body(GO:0033391) |
| 1.0 | 36.2 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.9 | 13.2 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.9 | 15.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.9 | 3.5 | GO:0055087 | Ski complex(GO:0055087) |
| 0.8 | 4.2 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.8 | 13.6 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.8 | 4.0 | GO:0016589 | NURF complex(GO:0016589) |
| 0.8 | 2.3 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
| 0.7 | 3.3 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 0.7 | 12.5 | GO:0030122 | AP-2 adaptor complex(GO:0030122) endolysosome membrane(GO:0036020) |
| 0.7 | 9.1 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.6 | 7.9 | GO:0042555 | MCM complex(GO:0042555) |
| 0.6 | 20.2 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.6 | 4.1 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.6 | 10.4 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.6 | 7.9 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.5 | 10.5 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.5 | 28.0 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.5 | 10.7 | GO:0042599 | lamellar body(GO:0042599) |
| 0.5 | 4.0 | GO:0005593 | FACIT collagen trimer(GO:0005593) |
| 0.5 | 2.0 | GO:0008043 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
| 0.4 | 5.8 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.4 | 5.6 | GO:0035631 | XY body(GO:0001741) CD40 receptor complex(GO:0035631) |
| 0.4 | 12.6 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.4 | 3.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.3 | 3.1 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.3 | 15.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.3 | 14.3 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.3 | 2.3 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.3 | 22.2 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.2 | 7.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.2 | 33.3 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.2 | 1.8 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.2 | 14.3 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.2 | 20.9 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.2 | 3.1 | GO:0090543 | Flemming body(GO:0090543) |
| 0.2 | 3.7 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.2 | 5.9 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.2 | 24.2 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 0.1 | 11.4 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.1 | 3.9 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.1 | 8.4 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 17.2 | GO:0000776 | kinetochore(GO:0000776) |
| 0.1 | 2.8 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 9.9 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.1 | 5.8 | GO:0005798 | Golgi-associated vesicle(GO:0005798) |
| 0.1 | 9.7 | GO:0001726 | ruffle(GO:0001726) |
| 0.1 | 16.3 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 7.2 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.1 | 0.9 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.1 | 11.9 | GO:0005840 | ribosome(GO:0005840) |
| 0.1 | 4.3 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.1 | 1.2 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 3.4 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 7.1 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 9.1 | GO:0030018 | Z disc(GO:0030018) |
| 0.1 | 16.8 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.1 | 6.9 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 2.0 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 1.0 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 4.2 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 3.2 | GO:0031301 | integral component of organelle membrane(GO:0031301) |
| 0.0 | 0.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 1.5 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 0.6 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.7 | 30.7 | GO:0005046 | KDEL sequence binding(GO:0005046) |
| 6.2 | 61.6 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 5.4 | 27.0 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
| 5.0 | 14.9 | GO:0003974 | UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978) |
| 3.7 | 11.1 | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates(GO:0016838) |
| 3.1 | 9.3 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 3.1 | 18.5 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 2.8 | 17.0 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 2.8 | 13.9 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 2.4 | 9.7 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
| 2.2 | 8.8 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 2.0 | 10.1 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 2.0 | 8.0 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 2.0 | 23.9 | GO:0031386 | protein tag(GO:0031386) |
| 2.0 | 9.9 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 1.9 | 5.7 | GO:0008309 | phosphodiesterase I activity(GO:0004528) double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
| 1.9 | 5.6 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 1.8 | 12.6 | GO:0016015 | morphogen activity(GO:0016015) |
| 1.7 | 45.3 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 1.7 | 34.4 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 1.5 | 6.1 | GO:0016936 | galactoside binding(GO:0016936) |
| 1.3 | 9.4 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
| 1.3 | 10.8 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 1.3 | 24.1 | GO:0016004 | phospholipase activator activity(GO:0016004) |
| 1.2 | 7.5 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 1.1 | 3.4 | GO:0033149 | FFAT motif binding(GO:0033149) |
| 1.1 | 6.7 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 1.0 | 6.1 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.9 | 35.6 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.9 | 5.4 | GO:0004167 | dopachrome isomerase activity(GO:0004167) |
| 0.9 | 18.9 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.9 | 26.9 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.9 | 6.2 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.9 | 11.4 | GO:0008252 | nucleotidase activity(GO:0008252) |
| 0.9 | 7.9 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.8 | 7.1 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.8 | 3.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.8 | 3.8 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.8 | 9.1 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.7 | 19.8 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.7 | 31.2 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.6 | 5.1 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.6 | 11.0 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.6 | 1.2 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 0.6 | 45.1 | GO:0019003 | GDP binding(GO:0019003) |
| 0.6 | 8.5 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.6 | 3.9 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.6 | 12.2 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.5 | 9.9 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.5 | 9.6 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.5 | 1.4 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.5 | 9.7 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.5 | 6.4 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.4 | 2.6 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.4 | 6.1 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.4 | 2.3 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.4 | 1.1 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 0.4 | 4.1 | GO:0089720 | caspase binding(GO:0089720) |
| 0.4 | 19.1 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.4 | 2.2 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.4 | 5.4 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.4 | 1.8 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.4 | 35.3 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.3 | 1.0 | GO:0033823 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211) |
| 0.3 | 13.2 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.3 | 0.9 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 0.3 | 8.5 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.3 | 1.9 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.3 | 14.3 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.3 | 5.8 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.3 | 0.8 | GO:0034353 | RNA pyrophosphohydrolase activity(GO:0034353) |
| 0.3 | 2.3 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 0.2 | 2.9 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
| 0.2 | 17.0 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.2 | 3.3 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.2 | 1.5 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.2 | 3.4 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.2 | 5.8 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.2 | 4.3 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.2 | 8.3 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.2 | 8.3 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.2 | 10.7 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.2 | 6.7 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.2 | 5.1 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.2 | 1.6 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.2 | 2.0 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.1 | 2.5 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.1 | 17.3 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.1 | 0.8 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
| 0.1 | 1.2 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.1 | 58.5 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 2.1 | GO:0019104 | DNA N-glycosylase activity(GO:0019104) |
| 0.1 | 1.7 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.1 | 16.3 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 3.6 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.1 | 12.9 | GO:0004386 | helicase activity(GO:0004386) |
| 0.1 | 4.0 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.1 | 1.7 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.1 | 0.8 | GO:0043559 | insulin binding(GO:0043559) |
| 0.1 | 0.8 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 0.1 | 2.8 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 1.2 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 0.1 | 10.0 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.1 | 3.0 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 2.3 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 5.8 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.1 | 2.3 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.1 | 1.0 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 5.8 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.1 | 7.4 | GO:0042393 | histone binding(GO:0042393) |
| 0.1 | 0.7 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.1 | 10.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 2.3 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.0 | 4.7 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 5.9 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 0.8 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.0 | 1.5 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.8 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.0 | 1.5 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 3.9 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 1.7 | GO:0016462 | pyrophosphatase activity(GO:0016462) |
| 0.0 | 13.8 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 0.7 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 12.1 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 1.0 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 0.4 | GO:0016891 | endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) |
| 0.0 | 21.0 | GO:0003723 | RNA binding(GO:0003723) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 48.2 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.5 | 65.3 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.4 | 8.0 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.3 | 16.1 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.3 | 7.6 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.3 | 9.2 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.3 | 13.1 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.3 | 8.1 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.3 | 14.7 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.2 | 11.3 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.2 | 18.3 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.2 | 16.9 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.2 | 10.1 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.2 | 8.9 | PID FOXO PATHWAY | FoxO family signaling |
| 0.2 | 9.7 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.2 | 6.5 | PID ATM PATHWAY | ATM pathway |
| 0.2 | 29.7 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
| 0.2 | 5.6 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.2 | 12.1 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.2 | 7.9 | PID ATR PATHWAY | ATR signaling pathway |
| 0.2 | 7.6 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.1 | 10.2 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.1 | 1.9 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 5.5 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 5.6 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.1 | 6.7 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 1.9 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.1 | 6.2 | PID BMP PATHWAY | BMP receptor signaling |
| 0.1 | 19.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 3.3 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 4.0 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.1 | 4.9 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.1 | 1.5 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 1.4 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 3.5 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 2.0 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.3 | 53.1 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 2.7 | 61.6 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 1.3 | 8.1 | REACTOME ER PHAGOSOME PATHWAY | Genes involved in ER-Phagosome pathway |
| 1.2 | 21.7 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 1.0 | 17.0 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 1.0 | 16.8 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.9 | 17.5 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.9 | 9.4 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.8 | 15.7 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 0.8 | 9.7 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.8 | 29.2 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.8 | 19.1 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.7 | 19.8 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.7 | 11.1 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.7 | 18.2 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.6 | 21.4 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.6 | 38.3 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.5 | 16.9 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.5 | 7.9 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.5 | 11.6 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 0.4 | 12.5 | REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
| 0.4 | 8.8 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.4 | 7.5 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.4 | 11.4 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.4 | 5.7 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.3 | 23.5 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.3 | 6.1 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.3 | 11.3 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.2 | 18.9 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.2 | 35.5 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.2 | 2.9 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.2 | 20.1 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.2 | 24.9 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.2 | 5.5 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.2 | 1.2 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.2 | 11.5 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.2 | 9.3 | REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.1 | 10.1 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.1 | 0.9 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.1 | 3.1 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.1 | 20.2 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.1 | 2.3 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 1.5 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 2.3 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 6.3 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.1 | 1.4 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 8.3 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 3.5 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 11.3 | REACTOME METABOLISM OF CARBOHYDRATES | Genes involved in Metabolism of carbohydrates |
| 0.0 | 3.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.7 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.4 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.8 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |