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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for AUGACAC
Z-value: 0.06
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miRNA associated with seed AUGACAC
| Name | miRBASE accession |
|---|---|
|
hsa-miR-425-5p
|
MIMAT0003393 |
Top targets:  
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_-_48937982 Show fit | 0.21 |
ENST00000316623.5
|
fibrillin 1 |
|
| chr6_-_86352642 Show fit | 0.12 |
ENST00000355238.6
|
synaptotagmin binding, cytoplasmic RNA interacting protein |
|
| chr10_+_89622870 Show fit | 0.11 |
ENST00000371953.3
|
phosphatase and tensin homolog |
|
| chr6_+_118869452 Show fit | 0.11 |
ENST00000357525.5
|
phospholamban |
|
| chr2_+_208394616 Show fit | 0.10 |
ENST00000432329.2
ENST00000353267.3 ENST00000445803.1 |
cAMP responsive element binding protein 1 |
|
| chr3_+_187930719 Show fit | 0.09 |
ENST00000312675.4
|
LIM domain containing preferred translocation partner in lipoma |
|
| chrX_-_119694538 Show fit | 0.08 |
ENST00000371322.5
|
cullin 4B |
|
| chr5_-_72744336 Show fit | 0.08 |
ENST00000499003.3
|
forkhead box D1 |
|
| chr12_-_102874416 Show fit | 0.07 |
ENST00000392904.1
ENST00000337514.6 |
insulin-like growth factor 1 (somatomedin C) |
|
| chr18_-_54305658 Show fit | 0.06 |
ENST00000586262.1
ENST00000217515.6 |
thioredoxin-like 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of AUGACAC
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0035582 | sequestering of BMP in extracellular matrix(GO:0035582) |
| 0.0 | 0.1 | GO:0086092 | regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) |
| 0.0 | 0.1 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.0 | 0.1 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 0.0 | 0.1 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.0 | 0.1 | GO:1904550 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.0 | 0.1 | GO:0072076 | nephrogenic mesenchyme development(GO:0072076) |
| 0.0 | 0.1 | GO:1904075 | trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) |
| 0.0 | 0.0 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.0 | 0.0 | GO:0008050 | female courtship behavior(GO:0008050) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.0 | 0.1 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.0 | 0.1 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.0 | 0.1 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.0 | 0.0 | GO:0031213 | RSF complex(GO:0031213) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.0 | 0.1 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 0.0 | 0.1 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.0 | 0.1 | GO:1990763 | arrestin family protein binding(GO:1990763) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |