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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for BARHL2

Z-value: 0.93

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Transcription factors associated with BARHL2

Gene Symbol Gene ID Gene Info
ENSG00000143032.7 BarH like homeobox 2

Activity profile of BARHL2 motif

Sorted Z-values of BARHL2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_238322800 34.14 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
collagen, type VI, alpha 3
chr2_-_238323007 30.08 ENST00000295550.4
collagen, type VI, alpha 3
chr2_-_238322770 27.25 ENST00000472056.1
collagen, type VI, alpha 3
chr12_-_91546926 23.81 ENST00000550758.1
decorin
chr12_-_91576561 18.87 ENST00000547568.2
ENST00000552962.1
decorin
chrX_+_114827818 18.69 ENST00000420625.2
plastin 3
chr12_-_91573132 17.90 ENST00000550563.1
ENST00000546370.1
decorin
chr11_+_92085262 14.88 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT atypical cadherin 3
chr13_-_38172863 14.33 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
periostin, osteoblast specific factor
chr12_-_91576429 14.31 ENST00000552145.1
ENST00000546745.1
decorin
chr12_-_91505608 13.49 ENST00000266718.4
lumican
chr4_+_169418195 12.57 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr19_-_6690723 10.69 ENST00000601008.1
complement component 3
chr7_+_107224364 9.69 ENST00000491150.1
B-cell receptor-associated protein 29
chr8_-_49833978 8.89 ENST00000020945.1
snail family zinc finger 2
chr8_-_49834299 8.57 ENST00000396822.1
snail family zinc finger 2
chr2_-_20251744 8.36 ENST00000175091.4
lysosomal protein transmembrane 4 alpha
chr3_-_123339343 6.64 ENST00000578202.1
myosin light chain kinase
chr1_-_95391315 6.59 ENST00000545882.1
ENST00000415017.1
calponin 3, acidic
chr10_-_95242044 6.58 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
myoferlin
chr12_-_6233828 6.33 ENST00000572068.1
ENST00000261405.5
von Willebrand factor
chr3_-_149095652 6.23 ENST00000305366.3
transmembrane 4 L six family member 1
chr10_-_28571015 5.92 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr11_+_101983176 5.65 ENST00000524575.1
Yes-associated protein 1
chr19_+_11651942 5.54 ENST00000587087.1
calponin 1, basic, smooth muscle
chr4_+_155484155 5.53 ENST00000509493.1
fibrinogen beta chain
chr15_-_37393406 5.45 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr9_-_14180778 5.37 ENST00000380924.1
ENST00000543693.1
nuclear factor I/B
chr2_-_188419078 5.37 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr15_+_58702742 5.09 ENST00000356113.6
ENST00000414170.3
lipase, hepatic
chr6_+_151646800 5.08 ENST00000354675.6
A kinase (PRKA) anchor protein 12
chr1_+_196788887 5.07 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr7_-_137028534 4.68 ENST00000348225.2
pleiotrophin
chr18_-_33702078 4.68 ENST00000586829.1
solute carrier family 39 (zinc transporter), member 6
chr3_+_52828805 4.67 ENST00000416872.2
ENST00000449956.2
inter-alpha-trypsin inhibitor heavy chain 3
chr2_-_86333244 4.66 ENST00000263857.6
ENST00000409681.1
polymerase (RNA) I polypeptide A, 194kDa
chrX_+_135251783 4.54 ENST00000394153.2
four and a half LIM domains 1
chr4_+_169418255 4.47 ENST00000505667.1
ENST00000511948.1
palladin, cytoskeletal associated protein
chr5_-_146781153 4.30 ENST00000520473.1
dihydropyrimidinase-like 3
chr4_-_89205879 4.29 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr19_+_9296279 4.28 ENST00000344248.2
olfactory receptor, family 7, subfamily D, member 2
chr17_-_64225508 4.23 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr4_+_155484103 4.17 ENST00000302068.4
fibrinogen beta chain
chr10_+_7745303 4.06 ENST00000429820.1
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr5_-_95297534 3.94 ENST00000513343.1
ENST00000431061.2
elongation factor, RNA polymerase II, 2
chrX_+_135252050 3.88 ENST00000449474.1
ENST00000345434.3
four and a half LIM domains 1
chr4_+_74269956 3.87 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
albumin
chr18_+_21529811 3.86 ENST00000588004.1
laminin, alpha 3
chr8_+_22424551 3.84 ENST00000523348.1
sorbin and SH3 domain containing 3
chr12_-_71551868 3.83 ENST00000247829.3
tetraspanin 8
chr5_-_41261540 3.71 ENST00000263413.3
complement component 6
chr18_+_3447572 3.70 ENST00000548489.2
TGFB-induced factor homeobox 1
chr14_+_23340822 3.69 ENST00000359591.4
low density lipoprotein receptor-related protein 10
chr7_-_137028498 3.69 ENST00000393083.2
pleiotrophin
chr19_-_43708378 3.63 ENST00000599746.1
pregnancy specific beta-1-glycoprotein 4
chr6_+_111580508 3.62 ENST00000368847.4
KIAA1919
chr18_+_29171689 3.61 ENST00000237014.3
transthyretin
chr10_-_52645379 3.55 ENST00000395489.2
APOBEC1 complementation factor
chr3_-_149093499 3.51 ENST00000472441.1
transmembrane 4 L six family member 1
chr9_-_95640218 3.48 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
zinc finger protein 484
chr9_-_95244781 3.47 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
asporin
chr2_-_188312971 3.47 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
calcitonin receptor-like
chr9_-_95298314 3.46 ENST00000344604.5
ENST00000375540.1
extracellular matrix protein 2, female organ and adipocyte specific
chr11_-_72070206 3.45 ENST00000544382.1
ClpB caseinolytic peptidase B homolog (E. coli)
chrX_+_135251835 3.45 ENST00000456445.1
four and a half LIM domains 1
chr8_+_105352050 3.37 ENST00000297581.2
dendrocyte expressed seven transmembrane protein
chr1_-_150780757 3.36 ENST00000271651.3
cathepsin K
chr12_-_53298841 3.28 ENST00000293308.6
keratin 8
chr12_-_103310987 3.26 ENST00000307000.2
phenylalanine hydroxylase
chr5_-_95297678 3.25 ENST00000237853.4
elongation factor, RNA polymerase II, 2
chr3_-_81792780 3.19 ENST00000489715.1
glucan (1,4-alpha-), branching enzyme 1
chr5_+_95066823 3.18 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr18_+_55888767 3.11 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr1_-_8000872 3.08 ENST00000377507.3
tumor necrosis factor receptor superfamily, member 9
chrX_-_18690210 3.08 ENST00000379984.3
retinoschisin 1
chr1_+_209878182 3.07 ENST00000367027.3
hydroxysteroid (11-beta) dehydrogenase 1
chr8_+_19796381 3.06 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
lipoprotein lipase
chr10_+_7745232 3.04 ENST00000358415.4
inter-alpha-trypsin inhibitor heavy chain 2
chr18_+_56530136 3.04 ENST00000591083.1
zinc finger protein 532
chr8_+_98881268 3.00 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
matrilin 2
chr4_-_10686475 2.93 ENST00000226951.6
cytokine-dependent hematopoietic cell linker
chr2_+_25015968 2.91 ENST00000380834.2
ENST00000473706.1
centromere protein O
chr4_+_70916119 2.85 ENST00000246896.3
ENST00000511674.1
histatin 1
chr11_+_114310164 2.81 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
RNA exonuclease 2
chr19_-_43382142 2.78 ENST00000597058.1
pregnancy specific beta-1-glycoprotein 1
chr8_-_87755878 2.78 ENST00000320005.5
cyclic nucleotide gated channel beta 3
chr2_+_11696464 2.75 ENST00000234142.5
growth regulation by estrogen in breast cancer 1
chr5_+_31193847 2.70 ENST00000514738.1
ENST00000265071.2
cadherin 6, type 2, K-cadherin (fetal kidney)
chrX_-_153602991 2.70 ENST00000369850.3
ENST00000422373.1
filamin A, alpha
chr1_+_196912902 2.68 ENST00000476712.2
ENST00000367415.5
complement factor H-related 2
chr3_-_165555200 2.66 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr1_+_89829610 2.63 ENST00000370456.4
ENST00000535065.1
guanylate binding protein family, member 6
chr2_-_177502254 2.62 ENST00000339037.3
long intergenic non-protein coding RNA 1116
chr2_-_225266743 2.62 ENST00000409685.3
family with sequence similarity 124B
chr2_+_33359646 2.61 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr14_-_38064198 2.59 ENST00000250448.2
forkhead box A1
chr18_+_55816546 2.57 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr22_-_36357671 2.55 ENST00000408983.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_+_184032419 2.55 ENST00000352767.3
ENST00000427141.2
eukaryotic translation initiation factor 4 gamma, 1
chr13_-_36920872 2.52 ENST00000451493.1
spastic paraplegia 20 (Troyer syndrome)
chr5_+_76011868 2.50 ENST00000319211.4
coagulation factor II (thrombin) receptor
chr22_-_36013368 2.48 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
myoglobin
chr4_+_70894130 2.48 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
histatin 3
chrX_-_15511438 2.46 ENST00000380420.5
pirin (iron-binding nuclear protein)
chr2_+_45168875 2.43 ENST00000260653.3
SIX homeobox 3
chr19_-_58326267 2.42 ENST00000391701.1
zinc finger protein 552
chr2_+_152214098 2.41 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr20_-_47804894 2.40 ENST00000371828.3
ENST00000371856.2
ENST00000360426.4
ENST00000347458.5
ENST00000340954.7
ENST00000371802.1
ENST00000371792.1
ENST00000437404.2
staufen double-stranded RNA binding protein 1
chr6_-_111927449 2.36 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3 interacting protein 2
chrX_-_130423200 2.35 ENST00000361420.3
immunoglobulin superfamily, member 1
chrX_+_105937068 2.34 ENST00000324342.3
ring finger protein 128, E3 ubiquitin protein ligase
chr5_-_82969405 2.34 ENST00000510978.1
hyaluronan and proteoglycan link protein 1
chr5_+_125758813 2.34 ENST00000285689.3
ENST00000515200.1
GRAM domain containing 3
chr17_+_45000483 2.34 ENST00000576910.2
ENST00000439730.2
ENST00000393456.2
ENST00000415811.2
ENST00000575949.1
ENST00000225567.4
ENST00000572403.1
ENST00000570879.1
golgi SNAP receptor complex member 2
chr6_+_161123270 2.34 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
plasminogen
chr1_-_110933663 2.29 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
solute carrier family 16, member 4
chr12_-_71551652 2.28 ENST00000546561.1
tetraspanin 8
chr19_-_7968427 2.27 ENST00000539278.1
Uncharacterized protein
chr11_+_114310102 2.27 ENST00000265881.5
RNA exonuclease 2
chr12_+_7013897 2.27 ENST00000007969.8
ENST00000323702.5
leucine rich repeat containing 23
chr17_+_37856299 2.25 ENST00000269571.5
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr12_-_102591604 2.24 ENST00000329406.4
pro-melanin-concentrating hormone
chr1_+_13910757 2.24 ENST00000376061.4
ENST00000513143.1
podoplanin
chr2_+_109237717 2.23 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr17_-_40288449 2.23 ENST00000552162.1
ENST00000550504.1
RAB5C, member RAS oncogene family
chr3_-_178984759 2.23 ENST00000349697.2
ENST00000497599.1
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr11_-_104035088 2.22 ENST00000302251.5
platelet derived growth factor D
chr1_-_110933611 2.21 ENST00000472422.2
ENST00000437429.2
solute carrier family 16, member 4
chr5_+_125758865 2.19 ENST00000542322.1
ENST00000544396.1
GRAM domain containing 3
chr8_-_23712312 2.19 ENST00000290271.2
stanniocalcin 1
chr10_-_29923893 2.19 ENST00000355867.4
supervillin
chr3_+_147127142 2.16 ENST00000282928.4
Zic family member 1
chr5_-_125930929 2.15 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
aldehyde dehydrogenase 7 family, member A1
chr2_+_66662510 2.15 ENST00000272369.9
ENST00000407092.2
Meis homeobox 1
chr1_+_22962948 2.13 ENST00000374642.3
complement component 1, q subcomponent, A chain
chr3_+_138340049 2.10 ENST00000464668.1
Fas apoptotic inhibitory molecule
chr16_+_72088376 2.08 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
haptoglobin
haptoglobin-related protein
chr18_+_21452804 2.08 ENST00000269217.6
laminin, alpha 3
chr17_+_70117153 2.08 ENST00000245479.2
SRY (sex determining region Y)-box 9
chr6_-_111927062 2.07 ENST00000359831.4
TRAF3 interacting protein 2
chr12_+_7014064 2.05 ENST00000443597.2
leucine rich repeat containing 23
chr12_+_58087901 2.04 ENST00000315970.7
ENST00000547079.1
ENST00000439210.2
ENST00000389146.6
ENST00000413095.2
ENST00000551035.1
ENST00000257966.8
ENST00000435406.2
ENST00000550372.1
ENST00000389142.5
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr3_+_130569429 2.04 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATPase, Ca++ transporting, type 2C, member 1
chr2_-_228582709 2.01 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
solute carrier family 19 (thiamine transporter), member 3
chr8_+_32579341 1.98 ENST00000519240.1
ENST00000539990.1
neuregulin 1
chr2_-_225266711 1.98 ENST00000389874.3
family with sequence similarity 124B
chrX_+_67718863 1.96 ENST00000374622.2
Yip1 domain family, member 6
chr3_+_69928256 1.95 ENST00000394355.2
microphthalmia-associated transcription factor
chr12_-_10978957 1.93 ENST00000240619.2
taste receptor, type 2, member 10
chr19_+_45409011 1.91 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
apolipoprotein E
chr14_+_32798547 1.90 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr18_-_33709268 1.90 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
solute carrier family 39 (zinc transporter), member 6
chr5_+_140593509 1.89 ENST00000341948.4
protocadherin beta 13
chr11_+_6411670 1.89 ENST00000530395.1
ENST00000527275.1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr4_+_56814968 1.87 ENST00000422247.2
centrosomal protein 135kDa
chr10_-_63995871 1.86 ENST00000315289.2
rhotekin 2
chr1_+_203651937 1.85 ENST00000341360.2
ATPase, Ca++ transporting, plasma membrane 4
chr3_-_55001115 1.85 ENST00000493075.1
leucine-rich repeats and transmembrane domains 1
chr10_-_50747064 1.85 ENST00000355832.5
ENST00000603152.1
ENST00000447839.2
excision repair cross-complementing rodent repair deficiency, complementation group 6
piggyBac transposable element derived 3
ERCC6-PGBD3 readthrough
chr7_+_116593292 1.84 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
suppression of tumorigenicity 7
chr6_-_131384347 1.82 ENST00000530481.1
erythrocyte membrane protein band 4.1-like 2
chr1_+_62439037 1.81 ENST00000545929.1
InaD-like (Drosophila)
chr16_-_53737722 1.80 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1-like
chr19_-_51530916 1.79 ENST00000594768.1
kallikrein-related peptidase 11
chr6_+_153552455 1.75 ENST00000392385.2
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr5_-_135290705 1.74 ENST00000274507.1
leukocyte cell-derived chemotaxin 2
chr8_-_16050288 1.74 ENST00000350896.3
macrophage scavenger receptor 1
chr10_+_13628933 1.73 ENST00000417658.1
ENST00000320054.4
pre-mRNA processing factor 18
chr7_-_14029515 1.73 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ets variant 1
chr12_+_26348246 1.73 ENST00000422622.2
sarcospan
chr5_-_55412774 1.70 ENST00000434982.2
ankyrin repeat domain 55
chr21_-_43735446 1.69 ENST00000398431.2
trefoil factor 3 (intestinal)
chr12_-_11062161 1.68 ENST00000390677.2
taste receptor, type 2, member 13
chr17_+_45726803 1.67 ENST00000535458.2
ENST00000583648.1
karyopherin (importin) beta 1
chr7_+_93535817 1.67 ENST00000248572.5
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr10_-_52645416 1.65 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
APOBEC1 complementation factor
chr4_-_165898768 1.65 ENST00000329314.5
tripartite motif containing 61
chr7_-_14029283 1.64 ENST00000433547.1
ENST00000405192.2
ets variant 1
chr7_-_27169801 1.64 ENST00000511914.1
homeobox A4
chr11_+_35201826 1.64 ENST00000531873.1
CD44 molecule (Indian blood group)
chr19_-_15560730 1.63 ENST00000389282.4
ENST00000263381.7
widely interspaced zinc finger motifs
chr6_+_26087509 1.62 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
hemochromatosis
chr4_+_88754069 1.62 ENST00000395102.4
ENST00000497649.2
matrix extracellular phosphoglycoprotein
chr3_+_38017264 1.62 ENST00000436654.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr1_+_236558694 1.60 ENST00000359362.5
EDAR-associated death domain
chr11_-_107590383 1.60 ENST00000525934.1
ENST00000531293.1
sarcolipin
chr4_-_70725856 1.59 ENST00000226444.3
sulfotransferase family 1E, estrogen-preferring, member 1
chr16_-_53737795 1.58 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1-like
chr12_+_41831485 1.58 ENST00000539469.2
ENST00000298919.7
PDZ domain containing ring finger 4
chr3_+_132316081 1.58 ENST00000249887.2
atypical chemokine receptor 4
chr14_-_82000140 1.57 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
sel-1 suppressor of lin-12-like (C. elegans)
chr16_+_58283814 1.56 ENST00000443128.2
ENST00000219299.4
coiled-coil domain containing 113
chr3_+_148709128 1.56 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
glycogenin 1
chr12_-_12503156 1.54 ENST00000543314.1
ENST00000396349.3
MANSC domain containing 1
chr8_-_86253888 1.53 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
carbonic anhydrase I
chr4_+_70861647 1.51 ENST00000246895.4
ENST00000381060.2
statherin
chr9_+_21409146 1.51 ENST00000380205.1
interferon, alpha 8
chr12_+_110011571 1.51 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
mevalonate kinase
chr1_+_44444865 1.51 ENST00000372324.1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr2_+_1417228 1.50 ENST00000382269.3
ENST00000337415.3
ENST00000345913.4
ENST00000346956.3
ENST00000349624.3
ENST00000539820.1
ENST00000329066.4
ENST00000382201.3
thyroid peroxidase

Network of associatons between targets according to the STRING database.

First level regulatory network of BARHL2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 74.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
5.8 17.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
4.8 14.3 GO:1990523 bone regeneration(GO:1990523)
4.2 8.4 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
3.6 14.4 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
2.1 2.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
1.7 5.1 GO:0014016 neuroblast differentiation(GO:0014016)
1.7 13.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
1.5 3.1 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
1.3 3.9 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
1.2 25.7 GO:0051764 actin crosslink formation(GO:0051764)
1.2 4.7 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
1.2 3.5 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
1.1 5.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
1.1 93.0 GO:0030574 collagen catabolic process(GO:0030574)
1.0 9.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.9 6.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.9 5.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.8 5.9 GO:0071896 protein localization to adherens junction(GO:0071896)
0.8 3.4 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.8 2.5 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.8 1.6 GO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
0.8 2.4 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.8 18.3 GO:0003334 keratinocyte development(GO:0003334)
0.8 7.8 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.8 2.3 GO:2000048 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.8 5.4 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.7 2.2 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.7 6.5 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.7 2.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.7 2.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.7 5.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.7 10.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.7 2.0 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.7 6.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.6 2.6 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.6 2.5 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.6 1.9 GO:1903248 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.6 6.6 GO:0001778 plasma membrane repair(GO:0001778)
0.6 1.2 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.6 1.1 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.6 7.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.5 1.6 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.5 5.4 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.5 1.6 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.5 1.6 GO:0006711 estrogen catabolic process(GO:0006711)
0.5 1.5 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.5 3.0 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.4 3.1 GO:0023021 termination of signal transduction(GO:0023021)
0.4 3.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.4 1.7 GO:0031291 Ran protein signal transduction(GO:0031291)
0.4 2.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.4 3.3 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.4 1.2 GO:0051541 elastin metabolic process(GO:0051541)
0.4 1.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.4 3.5 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.4 3.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 1.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.3 5.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 1.0 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.3 6.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.3 3.6 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.3 2.9 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.3 1.6 GO:1904383 response to sodium phosphate(GO:1904383)
0.3 2.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.3 1.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.3 2.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.3 2.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3 2.2 GO:0042426 choline catabolic process(GO:0042426)
0.3 3.4 GO:0021670 lateral ventricle development(GO:0021670)
0.3 2.0 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 1.4 GO:0007341 penetration of zona pellucida(GO:0007341)
0.3 5.5 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.3 1.9 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.3 1.8 GO:0007256 activation of JNKK activity(GO:0007256)
0.3 2.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.3 1.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.3 2.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.3 5.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.3 3.1 GO:0009642 response to light intensity(GO:0009642)
0.3 7.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.7 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.2 3.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.9 GO:0048859 formation of anatomical boundary(GO:0048859)
0.2 4.4 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.2 12.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 0.9 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2 4.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 1.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.2 3.3 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.2 1.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.2 1.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.2 0.6 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.2 1.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 1.3 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 10.4 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.2 1.0 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 1.0 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.2 1.0 GO:0097102 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) renal artery morphogenesis(GO:0061441) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 0.4 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 1.2 GO:0070092 response to selenium ion(GO:0010269) regulation of glucagon secretion(GO:0070092)
0.2 1.4 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 1.1 GO:0051012 microtubule sliding(GO:0051012)
0.2 1.5 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.2 2.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 0.5 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.2 1.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 1.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.2 1.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 0.5 GO:0051697 protein delipidation(GO:0051697)
0.2 4.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 0.5 GO:0048733 sebaceous gland development(GO:0048733)
0.2 2.2 GO:0072126 positive regulation of glomerular mesangial cell proliferation(GO:0072126)
0.2 0.9 GO:0030070 insulin processing(GO:0030070)
0.2 0.3 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.2 3.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.2 1.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.2 0.6 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.2 5.3 GO:0050832 defense response to fungus(GO:0050832)
0.2 1.2 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.2 1.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.2 3.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 3.9 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 1.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 1.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.7 GO:0050955 thermoception(GO:0050955)
0.1 0.7 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 1.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.8 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.5 GO:0042574 retinal metabolic process(GO:0042574)
0.1 2.2 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 0.7 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 4.0 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.9 GO:0019532 oxalate transport(GO:0019532)
0.1 2.4 GO:0005513 detection of calcium ion(GO:0005513)
0.1 3.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.4 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.1 0.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 1.1 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 1.0 GO:0016926 protein desumoylation(GO:0016926)
0.1 5.1 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 0.9 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.1 0.6 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.6 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 5.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.4 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 1.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 1.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 1.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.8 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.3 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.7 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.1 0.6 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 4.4 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 0.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 2.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 2.4 GO:0030728 ovulation(GO:0030728)
0.1 5.9 GO:0008542 visual learning(GO:0008542)
0.1 0.9 GO:2001135 constitutive secretory pathway(GO:0045054) regulation of endocytic recycling(GO:2001135)
0.1 1.6 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.3 GO:0044793 negative regulation by host of viral process(GO:0044793)
0.1 1.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.0 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.1 1.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.3 GO:0071435 potassium ion export(GO:0071435) regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.1 3.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.5 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.4 GO:0051597 response to methylmercury(GO:0051597)
0.1 1.2 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 2.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 3.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 1.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.7 GO:0010265 SCF complex assembly(GO:0010265)
0.1 6.5 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.7 GO:0000050 urea cycle(GO:0000050)
0.1 3.3 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 1.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.4 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 11.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.8 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.3 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.8 GO:0046548 retinal rod cell development(GO:0046548)
0.1 2.0 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 2.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 4.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 2.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.5 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 2.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 1.2 GO:0010842 retina layer formation(GO:0010842)
0.1 0.4 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1 1.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 5.9 GO:0070268 cornification(GO:0070268)
0.1 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 2.4 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.5 GO:0007632 visual behavior(GO:0007632)
0.1 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 3.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787) regulation of branching morphogenesis of a nerve(GO:2000172)
0.1 0.9 GO:0006907 pinocytosis(GO:0006907)
0.0 2.1 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 0.7 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 1.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:2001206 positive regulation of bone development(GO:1903012) positive regulation of osteoclast development(GO:2001206)
0.0 3.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.8 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.4 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.4 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.0 5.4 GO:0048839 inner ear development(GO:0048839)
0.0 0.4 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.9 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.3 GO:0009584 detection of visible light(GO:0009584)
0.0 0.7 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 1.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 0.7 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122) cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.7 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.3 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.6 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 2.6 GO:0050953 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0 0.7 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.4 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.3 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.8 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.5 GO:0014823 response to activity(GO:0014823)
0.0 1.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 2.0 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 1.2 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:0046606 negative regulation of centrosome cycle(GO:0046606)
0.0 0.3 GO:0097502 mannosylation(GO:0097502)
0.0 0.1 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
11.9 166.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.7 5.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.1 5.6 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.1 3.4 GO:0005879 axonemal microtubule(GO:0005879)
1.1 13.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.9 7.3 GO:0005610 laminin-5 complex(GO:0005610)
0.9 2.7 GO:0031523 Myb complex(GO:0031523)
0.7 9.7 GO:0005577 fibrinogen complex(GO:0005577)
0.7 3.6 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.6 1.9 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.5 6.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.5 2.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.5 8.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.5 5.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.5 1.4 GO:0043159 acrosomal matrix(GO:0043159)
0.5 1.8 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.4 5.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.4 2.1 GO:0005602 complement component C1 complex(GO:0005602)
0.4 3.7 GO:0005579 membrane attack complex(GO:0005579)
0.4 2.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.4 2.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.3 19.2 GO:0002102 podosome(GO:0002102)
0.3 3.5 GO:0005614 interstitial matrix(GO:0005614)
0.3 11.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 25.1 GO:0031594 neuromuscular junction(GO:0031594)
0.3 1.4 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.3 1.6 GO:1990357 terminal web(GO:1990357)
0.3 1.3 GO:0000801 central element(GO:0000801)
0.3 4.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 2.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 26.8 GO:0032432 actin filament bundle(GO:0032432)
0.2 6.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 4.2 GO:0042599 lamellar body(GO:0042599)
0.2 11.8 GO:0034358 plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.2 0.8 GO:0035838 growing cell tip(GO:0035838)
0.2 1.0 GO:0030905 retromer, tubulation complex(GO:0030905)
0.2 0.7 GO:0071564 npBAF complex(GO:0071564)
0.2 1.6 GO:0034451 centriolar satellite(GO:0034451)
0.2 0.6 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.7 GO:0071546 pi-body(GO:0071546)
0.1 1.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 4.3 GO:0031941 filamentous actin(GO:0031941)
0.1 0.9 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 1.8 GO:0008091 spectrin(GO:0008091)
0.1 3.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 1.0 GO:0097443 sorting endosome(GO:0097443)
0.1 0.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.3 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 0.8 GO:0036021 endolysosome lumen(GO:0036021)
0.1 2.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.4 GO:0043194 axon initial segment(GO:0043194)
0.1 0.5 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 0.9 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 2.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 4.9 GO:0005771 multivesicular body(GO:0005771)
0.1 5.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.1 14.9 GO:0072562 blood microparticle(GO:0072562)
0.1 6.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.1 GO:0097386 glial cell projection(GO:0097386)
0.1 0.7 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.9 GO:0097440 apical dendrite(GO:0097440)
0.1 1.9 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.4 GO:0009986 cell surface(GO:0009986)
0.1 0.5 GO:0000322 storage vacuole(GO:0000322)
0.1 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.1 4.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.6 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 3.0 GO:0005902 microvillus(GO:0005902)
0.1 2.3 GO:0045095 keratin filament(GO:0045095)
0.1 4.3 GO:0005811 lipid particle(GO:0005811)
0.1 5.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.1 GO:0000776 kinetochore(GO:0000776)
0.0 2.6 GO:0005882 intermediate filament(GO:0005882)
0.0 1.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 3.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.2 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 9.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 4.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.6 GO:0005604 basement membrane(GO:0005604)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.1 GO:0044853 plasma membrane raft(GO:0044853)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.7 GO:0099738 cell cortex region(GO:0099738)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.7 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 6.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 10.7 GO:0000790 nuclear chromatin(GO:0000790)
0.0 6.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 2.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 1.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.5 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.7 GO:0031526 brush border membrane(GO:0031526)
0.0 1.6 GO:0005814 centriole(GO:0005814)
0.0 2.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0045177 apical part of cell(GO:0045177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 2.7 GO:0003990 acetylcholinesterase activity(GO:0003990)
2.1 8.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.3 6.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.2 3.5 GO:0070052 collagen V binding(GO:0070052)
1.0 100.2 GO:0005518 collagen binding(GO:0005518)
1.0 1.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
1.0 3.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.0 3.1 GO:0017129 triglyceride binding(GO:0017129)
1.0 107.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.9 3.5 GO:0004948 calcitonin receptor activity(GO:0004948)
0.8 4.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.8 3.3 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.7 4.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.7 5.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.7 2.7 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.7 2.0 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.7 15.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.6 1.9 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.6 1.9 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.5 1.6 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.5 1.6 GO:0070984 SET domain binding(GO:0070984)
0.5 2.6 GO:0050436 microfibril binding(GO:0050436)
0.5 1.5 GO:0046848 hydroxyapatite binding(GO:0046848)
0.5 3.8 GO:0034711 inhibin binding(GO:0034711)
0.5 1.4 GO:0004040 amidase activity(GO:0004040) fucose binding(GO:0042806)
0.5 7.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 1.3 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.4 2.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.4 2.4 GO:0004447 iodide peroxidase activity(GO:0004447)
0.4 2.8 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.4 9.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.4 4.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.4 1.6 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.4 1.5 GO:0004461 lactose synthase activity(GO:0004461)
0.4 3.7 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.4 3.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.3 2.1 GO:0030492 hemoglobin binding(GO:0030492)
0.3 6.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 3.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.3 1.4 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.3 1.0 GO:0003883 CTP synthase activity(GO:0003883)
0.3 1.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 4.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.3 3.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 3.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 2.3 GO:0004064 arylesterase activity(GO:0004064)
0.3 0.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 1.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 4.2 GO:0015643 toxic substance binding(GO:0015643)
0.3 2.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.3 4.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.3 0.8 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.2 1.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 6.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 1.0 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 2.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 1.6 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.2 2.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 2.6 GO:1990459 transferrin receptor binding(GO:1990459)
0.2 1.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 0.6 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.2 0.6 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.2 1.3 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 1.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 5.6 GO:0070064 proline-rich region binding(GO:0070064)
0.2 4.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 2.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.2 1.8 GO:0042731 PH domain binding(GO:0042731)
0.2 0.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 1.9 GO:0051434 BH3 domain binding(GO:0051434)
0.2 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.2 0.6 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 4.0 GO:0017166 vinculin binding(GO:0017166)
0.2 3.7 GO:0070410 co-SMAD binding(GO:0070410)
0.2 1.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 2.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 0.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 2.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 5.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 0.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 1.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 2.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.8 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 6.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.7 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 19.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 3.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.9 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.6 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 5.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.4 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 1.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 15.6 GO:0008201 heparin binding(GO:0008201)
0.1 0.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 1.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.5 GO:0002046 opsin binding(GO:0002046)
0.1 0.6 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 3.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 2.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 9.2 GO:0051087 chaperone binding(GO:0051087)
0.1 0.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.4 GO:0005537 mannose binding(GO:0005537)
0.1 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 1.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.4 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 1.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 7.0 GO:0032947 protein complex scaffold(GO:0032947)
0.1 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.1 GO:0070330 aromatase activity(GO:0070330)
0.1 2.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 10.3 GO:0044325 ion channel binding(GO:0044325)
0.1 0.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.0 GO:0008494 translation activator activity(GO:0008494)
0.1 1.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.1 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 2.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.4 GO:0019956 chemokine binding(GO:0019956)
0.1 1.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 5.4 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 0.2 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 0.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 5.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 2.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.8 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 2.2 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 0.9 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 3.0 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 22.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 2.7 GO:0051117 ATPase binding(GO:0051117)
0.0 7.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 2.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 3.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.5 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 2.2 GO:0051015 actin filament binding(GO:0051015)
0.0 1.0 GO:0008083 growth factor activity(GO:0008083)
0.0 1.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.6 GO:0002020 protease binding(GO:0002020)
0.0 0.4 GO:0050662 coenzyme binding(GO:0050662)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 91.5 NABA COLLAGENS Genes encoding collagen proteins
1.7 94.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.5 10.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 7.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 6.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 14.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 6.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 1.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 31.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 5.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 2.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 13.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 10.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 5.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.1 PID CD40 PATHWAY CD40/CD40L signaling
0.1 2.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.8 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 7.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 7.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 3.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 4.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.9 PID ARF 3PATHWAY Arf1 pathway
0.1 4.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 3.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 3.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.6 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 5.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 2.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 3.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 2.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 PID SHP2 PATHWAY SHP2 signaling
0.0 10.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.5 PID FOXO PATHWAY FoxO family signaling
0.0 2.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 3.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 73.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.4 91.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
1.1 15.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.6 16.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.6 12.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.5 10.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 6.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.4 6.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 2.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 6.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 3.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.2 4.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 5.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 5.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 5.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 3.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 11.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 1.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.2 7.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2 1.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.2 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.2 2.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 3.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 5.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 4.6 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 4.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 4.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 5.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 12.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 4.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 3.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 4.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 4.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 0.8 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 4.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 0.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 3.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.7 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 2.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 2.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 3.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 1.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.8 REACTOME MRNA PROCESSING Genes involved in mRNA Processing