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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for CAGUAGU

Z-value: 0.89

Motif logo

miRNA associated with seed CAGUAGU

NamemiRBASE accession
MIMAT0000232
MIMAT0004563
MIMAT0014992

Activity profile of CAGUAGU motif

Sorted Z-values of CAGUAGU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_165796753 21.64 ENST00000367879.4
uridine-cytidine kinase 2
chr11_+_35160709 18.81 ENST00000415148.2
ENST00000433354.2
ENST00000449691.2
ENST00000437706.2
ENST00000360158.4
ENST00000428726.2
ENST00000526669.2
ENST00000433892.2
ENST00000278386.6
ENST00000434472.2
ENST00000352818.4
ENST00000442151.2
CD44 molecule (Indian blood group)
chr6_+_47445467 18.24 ENST00000359314.5
CD2-associated protein
chr12_-_31479045 16.61 ENST00000539409.1
ENST00000395766.1
family with sequence similarity 60, member A
chr10_+_74033672 14.55 ENST00000307365.3
DNA-damage-inducible transcript 4
chr11_+_832944 13.34 ENST00000322008.4
ENST00000397421.1
ENST00000529810.1
ENST00000526693.1
ENST00000525333.1
ENST00000524748.1
ENST00000527341.1
CD151 molecule (Raph blood group)
chr7_+_116139424 12.81 ENST00000222693.4
caveolin 2
chr12_-_80084862 11.05 ENST00000328827.4
PRKC, apoptosis, WT1, regulator
chr12_-_46662772 10.72 ENST00000549049.1
ENST00000439706.1
ENST00000398637.5
solute carrier family 38, member 1
chr3_+_180630090 10.71 ENST00000357559.4
ENST00000305586.7
fragile X mental retardation, autosomal homolog 1
chr7_-_95064264 10.45 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
paraoxonase 2
chr20_-_52210368 10.44 ENST00000371471.2
zinc finger protein 217
chr14_+_56046914 10.31 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
kinectin 1 (kinesin receptor)
chr6_+_13615554 10.10 ENST00000451315.2
nucleolar protein 7, 27kDa
chr2_-_47168906 10.09 ENST00000444761.2
ENST00000409147.1
multiple coagulation factor deficiency 2
chr2_+_85198216 10.07 ENST00000456682.1
ENST00000409785.4
potassium channel modulatory factor 1
chr2_+_36582857 10.07 ENST00000280527.2
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr6_-_24721054 9.82 ENST00000378119.4
chromosome 6 open reading frame 62
chr5_-_172756506 9.55 ENST00000265087.4
stanniocalcin 2
chr1_+_7831323 9.30 ENST00000054666.6
vesicle-associated membrane protein 3
chr12_-_48099773 8.69 ENST00000432584.3
ENST00000005386.3
RNA polymerase II associated protein 3
chr1_+_116184566 8.59 ENST00000355485.2
ENST00000369510.4
VANGL planar cell polarity protein 1
chr14_-_64010046 8.54 ENST00000337537.3
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr10_+_60144782 8.43 ENST00000487519.1
transcription factor A, mitochondrial
chr9_+_2621798 8.06 ENST00000382100.3
very low density lipoprotein receptor
chr15_-_56209306 7.99 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr15_-_49447835 7.98 ENST00000388901.5
ENST00000299259.6
COP9 signalosome subunit 2
chr1_-_94079648 7.88 ENST00000370247.3
breast cancer anti-estrogen resistance 3
chr3_+_61547585 7.59 ENST00000295874.10
ENST00000474889.1
protein tyrosine phosphatase, receptor type, G
chr10_+_5454505 7.27 ENST00000355029.4
neuroepithelial cell transforming 1
chr3_+_152017181 6.91 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
muscleblind-like splicing regulator 1
chr10_-_88281494 6.74 ENST00000298767.5
wings apart-like homolog (Drosophila)
chr3_-_98620500 6.59 ENST00000326840.6
discoidin, CUB and LCCL domain containing 2
chr12_-_120687948 6.49 ENST00000458477.2
paxillin
chr8_+_26149007 6.38 ENST00000380737.3
ENST00000524169.1
protein phosphatase 2, regulatory subunit B, alpha
chr4_-_40631859 6.26 ENST00000295971.7
ENST00000319592.4
RNA binding motif protein 47
chr7_-_19157248 6.09 ENST00000242261.5
twist family bHLH transcription factor 1
chr2_+_48010221 5.82 ENST00000234420.5
mutS homolog 6
chr2_-_106810783 5.73 ENST00000283148.7
UDP-glucuronate decarboxylase 1
chr8_-_17104356 5.62 ENST00000361272.4
ENST00000523917.1
CCR4-NOT transcription complex, subunit 7
chr15_-_37390482 5.53 ENST00000559085.1
ENST00000397624.3
Meis homeobox 2
chr5_+_52083730 5.51 ENST00000282588.6
ENST00000274311.2
integrin, alpha 1
pelota homolog (Drosophila)
chr4_-_76598296 5.42 ENST00000395719.3
GTPase activating protein (SH3 domain) binding protein 2
chr11_+_101981169 5.38 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
Yes-associated protein 1
chr14_+_103058948 5.35 ENST00000262241.6
REST corepressor 1
chr2_+_173292301 5.00 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
integrin, alpha 6
chr3_+_110790590 4.67 ENST00000485303.1
poliovirus receptor-related 3
chr17_+_30264014 4.63 ENST00000322652.5
ENST00000580398.1
SUZ12 polycomb repressive complex 2 subunit
chr16_+_67880574 4.59 ENST00000219169.4
nuclear transport factor 2
chr5_-_121413974 4.50 ENST00000231004.4
lysyl oxidase
chrX_-_77150985 4.49 ENST00000358075.6
magnesium transporter 1
chr15_-_77363513 4.48 ENST00000267970.4
tetraspanin 3
chr5_-_148930960 4.36 ENST00000261798.5
ENST00000377843.2
casein kinase 1, alpha 1
chrX_+_40944871 4.24 ENST00000378308.2
ENST00000324545.8
ubiquitin specific peptidase 9, X-linked
chr1_-_211752073 4.19 ENST00000367001.4
solute carrier family 30 (zinc transporter), member 1
chr4_+_55095264 4.15 ENST00000257290.5
platelet-derived growth factor receptor, alpha polypeptide
chr4_-_139163491 4.12 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr7_-_105752651 3.98 ENST00000470347.1
ENST00000455385.2
synaptophysin-like 1
chr21_-_46238034 3.95 ENST00000332859.6
small ubiquitin-like modifier 3
chr10_+_82213904 3.90 ENST00000429989.3
tetraspanin 14
chr20_+_31407692 3.75 ENST00000375571.5
microtubule-associated protein, RP/EB family, member 1
chr2_+_27440229 3.72 ENST00000264705.4
ENST00000403525.1
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr9_+_33265011 3.58 ENST00000419016.2
charged multivesicular body protein 5
chr8_-_130951940 3.49 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
family with sequence similarity 49, member B
chr4_+_41937131 3.47 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
transmembrane protein 33
chr7_+_128379346 3.42 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
calumenin
chr11_-_44331679 3.36 ENST00000329255.3
ALX homeobox 4
chr2_-_216300784 3.32 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
fibronectin 1
chr4_-_74124502 3.30 ENST00000358602.4
ENST00000330838.6
ENST00000561029.1
ankyrin repeat domain 17
chr6_+_7107999 3.23 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
ras responsive element binding protein 1
chr7_-_83824169 3.20 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_-_57123815 3.18 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
pleiomorphic adenoma gene 1
chr17_+_34900737 3.06 ENST00000304718.4
ENST00000485685.2
gametogenetin binding protein 2
chr10_+_112257596 3.00 ENST00000369583.3
dual specificity phosphatase 5
chr4_+_123747834 2.99 ENST00000264498.3
fibroblast growth factor 2 (basic)
chr2_-_37899323 2.95 ENST00000295324.3
ENST00000457889.1
CDC42 effector protein (Rho GTPase binding) 3
chr3_+_38206975 2.94 ENST00000446845.1
ENST00000311806.3
oxidative stress responsive 1
chr1_-_235491462 2.89 ENST00000418304.1
ENST00000264183.3
ENST00000349213.3
AT rich interactive domain 4B (RBP1-like)
chr1_+_87170247 2.83 ENST00000370558.4
SH3-domain GRB2-like endophilin B1
chr1_+_65613217 2.82 ENST00000545314.1
adenylate kinase 4
chr17_+_36861735 2.68 ENST00000378137.5
ENST00000325718.7
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr17_-_1303462 2.67 ENST00000573026.1
ENST00000575977.1
ENST00000571732.1
ENST00000264335.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
chr13_+_48877895 2.67 ENST00000267163.4
retinoblastoma 1
chr3_+_107241783 2.66 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
bobby sox homolog (Drosophila)
chr12_-_76478686 2.63 ENST00000261182.8
nucleosome assembly protein 1-like 1
chr19_+_1407517 2.52 ENST00000336761.6
ENST00000233078.4
DAZ associated protein 1
chr6_+_161412759 2.51 ENST00000366919.2
ENST00000392142.4
ENST00000366920.2
ENST00000348824.7
mitogen-activated protein kinase kinase kinase 4
chr7_-_129592700 2.42 ENST00000472396.1
ENST00000355621.3
ubiquitin-conjugating enzyme E2H
chr15_+_41523335 2.38 ENST00000334660.5
calcineurin-like EF-hand protein 1
chr5_-_77590480 2.32 ENST00000519295.1
ENST00000255194.6
adaptor-related protein complex 3, beta 1 subunit
chr3_-_185655795 2.25 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
transformer 2 beta homolog (Drosophila)
chr3_-_24536253 2.19 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
thyroid hormone receptor, beta
chr12_-_77272765 2.15 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
cysteine and glycine-rich protein 2
chr2_+_42396472 2.14 ENST00000318522.5
ENST00000402711.2
echinoderm microtubule associated protein like 4
chr10_+_31608054 2.08 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
zinc finger E-box binding homeobox 1
chr17_+_5185552 1.95 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
rabaptin, RAB GTPase binding effector protein 1
chr2_+_110371905 1.90 ENST00000356454.3
sosondowah ankyrin repeat domain family member C
chr12_+_22778009 1.88 ENST00000266517.4
ENST00000335148.3
ethanolamine kinase 1
chr13_-_76056250 1.82 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
TBC1 domain family, member 4
chr11_+_92085262 1.81 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT atypical cadherin 3
chrX_+_117861535 1.78 ENST00000371666.3
ENST00000371642.1
interleukin 13 receptor, alpha 1
chr4_-_129208940 1.77 ENST00000296425.5
progesterone receptor membrane component 2
chr4_-_79860506 1.61 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
progestin and adipoQ receptor family member III
chr6_-_90062543 1.61 ENST00000435041.2
ubiquitin-conjugating enzyme E2, J1
chr1_-_78444776 1.56 ENST00000370767.1
ENST00000421641.1
far upstream element (FUSE) binding protein 1
chr4_-_73434498 1.54 ENST00000286657.4
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr6_-_139695757 1.54 ENST00000367651.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr8_-_101965146 1.53 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr7_-_27205136 1.51 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr2_-_208030647 1.50 ENST00000309446.6
Kruppel-like factor 7 (ubiquitous)
chr6_+_84569359 1.49 ENST00000369681.5
ENST00000369679.4
cytochrome b5 reductase 4
chrX_+_16964794 1.48 ENST00000357277.3
RALBP1 associated Eps domain containing 2
chrX_+_78003204 1.45 ENST00000435339.3
ENST00000514744.1
lysophosphatidic acid receptor 4
chr4_-_39979576 1.43 ENST00000303538.8
ENST00000503396.1
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr13_-_30169807 1.43 ENST00000380752.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr5_+_141348598 1.39 ENST00000394520.2
ENST00000347642.3
ring finger protein 14
chr1_-_93645818 1.38 ENST00000370280.1
ENST00000479918.1
transmembrane emp24 protein transport domain containing 5
chr2_+_191273052 1.35 ENST00000417958.1
ENST00000432036.1
ENST00000392328.1
major facilitator superfamily domain containing 6
chr11_+_129939779 1.31 ENST00000533195.1
ENST00000533713.1
ENST00000528499.1
ENST00000539648.1
ENST00000263574.5
amyloid beta (A4) precursor-like protein 2
chr15_+_85523671 1.23 ENST00000310298.4
ENST00000557957.1
phosphodiesterase 8A
chr22_+_21771656 1.23 ENST00000407464.2
hypermethylated in cancer 2
chr14_-_52535712 1.22 ENST00000216286.5
ENST00000541773.1
nidogen 2 (osteonidogen)
chr12_-_57030115 1.22 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
bromodomain adjacent to zinc finger domain, 2A
chr5_-_16936340 1.14 ENST00000507288.1
ENST00000513610.1
myosin X
chrX_+_12993202 1.14 ENST00000451311.2
ENST00000380636.1
thymosin beta 4, X-linked
chr10_+_102106829 1.13 ENST00000370355.2
stearoyl-CoA desaturase (delta-9-desaturase)
chr1_+_2985760 1.13 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
PR domain containing 16
chr14_+_23067146 1.12 ENST00000428304.2
abhydrolase domain containing 4
chr12_+_14518598 1.08 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
activating transcription factor 7 interacting protein
chr1_+_224301787 1.08 ENST00000366862.5
ENST00000424254.2
F-box protein 28
chr3_-_69435224 1.00 ENST00000398540.3
FERM domain containing 4B
chr9_-_107690420 0.97 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ATP-binding cassette, sub-family A (ABC1), member 1
chr3_+_37284668 0.97 ENST00000361924.2
ENST00000444882.1
ENST00000356847.4
ENST00000450863.2
ENST00000429018.1
golgin A4
chr5_-_179780312 0.97 ENST00000253778.8
glutamine-fructose-6-phosphate transaminase 2
chr15_+_49715293 0.95 ENST00000267843.4
ENST00000560270.1
fibroblast growth factor 7
chr6_+_163835669 0.92 ENST00000453779.2
ENST00000275262.7
ENST00000392127.2
ENST00000361752.3
QKI, KH domain containing, RNA binding
chr16_-_71758602 0.91 ENST00000568954.1
PH domain and leucine rich repeat protein phosphatase 2
chr20_-_14318248 0.89 ENST00000378053.3
ENST00000341420.4
fibronectin leucine rich transmembrane protein 3
chr8_-_89339705 0.88 ENST00000286614.6
matrix metallopeptidase 16 (membrane-inserted)
chr3_-_138553594 0.86 ENST00000477593.1
ENST00000483968.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr1_-_46152174 0.85 ENST00000290795.3
ENST00000355105.3
GC-rich promoter binding protein 1-like 1
chr3_-_11762202 0.84 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
vestigial like 4 (Drosophila)
chr2_-_24149977 0.82 ENST00000238789.5
ATPase family, AAA domain containing 2B
chr8_+_29952914 0.73 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
leptin receptor overlapping transcript-like 1
chrX_+_107683096 0.69 ENST00000328300.6
ENST00000361603.2
collagen, type IV, alpha 5
chr1_+_161736072 0.66 ENST00000367942.3
activating transcription factor 6
chr6_+_10556215 0.53 ENST00000316170.3
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr12_-_498620 0.53 ENST00000399788.2
ENST00000382815.4
lysine (K)-specific demethylase 5A
chr12_-_102874416 0.52 ENST00000392904.1
ENST00000337514.6
insulin-like growth factor 1 (somatomedin C)
chr9_+_77112244 0.52 ENST00000376896.3
RAR-related orphan receptor B
chr6_+_26365443 0.50 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
butyrophilin, subfamily 3, member A2
chr10_+_20105157 0.48 ENST00000377242.3
ENST00000377252.4
plexin domain containing 2
chr5_-_100238956 0.46 ENST00000231461.5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr17_+_73521763 0.46 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
lethal giant larvae homolog 2 (Drosophila)
chr11_+_120207787 0.45 ENST00000397843.2
ENST00000356641.3
Rho guanine nucleotide exchange factor (GEF) 12
chrX_+_16804544 0.41 ENST00000380122.5
ENST00000398155.4
taxilin gamma
chr2_-_224903995 0.36 ENST00000409304.1
ENST00000454956.1
ENST00000258405.4
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr12_+_53774423 0.36 ENST00000426431.2
Sp1 transcription factor
chrX_-_83442915 0.36 ENST00000262752.2
ENST00000543399.1
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr2_+_44396000 0.31 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr15_-_56535464 0.26 ENST00000559447.2
ENST00000422057.1
ENST00000317318.6
ENST00000423270.1
regulatory factor X, 7
chr1_-_184723942 0.25 ENST00000318130.8
ER degradation enhancer, mannosidase alpha-like 3
chr4_+_148538517 0.24 ENST00000296582.3
ENST00000508208.1
transmembrane protein 184C
chr7_-_105517021 0.23 ENST00000318724.4
ENST00000419735.3
ataxin 7-like 1
chr15_+_90544532 0.23 ENST00000268154.4
zinc finger protein 710
chr11_+_12695944 0.20 ENST00000361905.4
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr6_+_89790490 0.18 ENST00000336032.3
proline-rich nuclear receptor coactivator 1
chr15_-_61521495 0.17 ENST00000335670.6
RAR-related orphan receptor A
chr3_+_137906109 0.17 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
armadillo repeat containing 8
chr16_+_81348528 0.16 ENST00000568107.2
gigaxonin
chr5_+_112312416 0.10 ENST00000389063.2
decapping mRNA 2
chr8_+_81397876 0.10 ENST00000430430.1
zinc finger and BTB domain containing 10
chr2_+_138721850 0.07 ENST00000329366.4
ENST00000280097.3
histamine N-methyltransferase
chr15_+_84322827 0.06 ENST00000286744.5
ENST00000567476.1
ADAMTS-like 3
chr16_-_1464688 0.02 ENST00000389221.4
ENST00000508903.2
ENST00000397462.1
ENST00000301712.5
unkempt family zinc finger-like
chr1_+_167190066 0.01 ENST00000367866.2
ENST00000429375.2
ENST00000452019.1
ENST00000420254.3
ENST00000541643.3
POU class 2 homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of CAGUAGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
5.4 21.6 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
2.8 11.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
2.4 18.8 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
2.1 12.8 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
2.1 8.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
2.0 6.1 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
2.0 8.0 GO:0044111 development involved in symbiotic interaction(GO:0044111)
1.6 8.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
1.4 2.9 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
1.4 4.2 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.3 9.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
1.3 7.6 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
1.3 3.8 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
1.2 3.7 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
1.2 9.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
1.2 3.5 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.1 4.6 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
1.1 3.3 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
1.0 6.3 GO:0016554 cytidine to uridine editing(GO:0016554)
1.0 3.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
1.0 2.9 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.9 2.8 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.9 5.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.9 2.7 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.9 14.6 GO:0051198 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.8 4.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.8 5.8 GO:0000710 meiotic mismatch repair(GO:0000710)
0.8 3.3 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.8 5.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.8 3.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.8 1.5 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.6 3.2 GO:0048880 sensory system development(GO:0048880)
0.6 18.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.6 2.5 GO:0007538 primary sex determination(GO:0007538)
0.6 4.4 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.6 5.4 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.6 3.5 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.6 2.3 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.6 4.5 GO:0015693 magnesium ion transport(GO:0015693)
0.6 2.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.6 7.3 GO:0051451 myoblast migration(GO:0051451)
0.5 2.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.5 5.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.5 2.7 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.5 8.0 GO:0000338 protein deneddylation(GO:0000338)
0.5 1.0 GO:0060437 lung growth(GO:0060437)
0.5 2.8 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.5 1.8 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.5 10.4 GO:0019372 lipoxygenase pathway(GO:0019372)
0.4 10.7 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.4 6.6 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.4 14.8 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.4 4.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 1.4 GO:1903826 arginine transmembrane transport(GO:1903826)
0.3 6.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.3 3.0 GO:0060591 chondroblast differentiation(GO:0060591)
0.3 7.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.3 2.4 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.3 3.0 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.3 6.5 GO:0007172 signal complex assembly(GO:0007172)
0.3 3.6 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.3 1.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 1.0 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.2 2.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602) semicircular canal morphogenesis(GO:0048752)
0.2 6.7 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.2 1.6 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 0.9 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 3.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 3.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.2 4.6 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.2 10.1 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.2 0.5 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.2 1.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 1.5 GO:0090168 Golgi reassembly(GO:0090168)
0.1 3.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.7 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 2.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.5 GO:0042118 endothelial cell activation(GO:0042118)
0.1 6.7 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 0.7 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.9 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 1.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 1.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.4 GO:0021683 cerebellar granular layer morphogenesis(GO:0021683)
0.1 3.4 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.1 0.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.4 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 0.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 1.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 4.0 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.1 0.9 GO:0061158 long-chain fatty acid biosynthetic process(GO:0042759) 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.5 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 8.6 GO:0043473 pigmentation(GO:0043473)
0.1 0.4 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 2.6 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.2 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 2.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 1.2 GO:0071711 basement membrane organization(GO:0071711)
0.0 6.9 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.4 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 1.2 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 4.2 GO:0007292 female gamete generation(GO:0007292)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.1 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 2.0 GO:0008542 visual learning(GO:0008542)
0.0 0.2 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 1.1 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 1.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 12.7 GO:0043687 post-translational protein modification(GO:0043687)
0.0 6.8 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 1.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.5 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 2.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.5 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 7.2 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.7 GO:0007528 neuromuscular junction development(GO:0007528)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 18.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.8 5.5 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
1.7 5.0 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
1.5 5.8 GO:0032301 MutSalpha complex(GO:0032301)
1.4 5.6 GO:0044094 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
1.1 5.6 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.9 2.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.9 8.7 GO:0097255 R2TP complex(GO:0097255)
0.7 16.6 GO:0016580 Sin3 complex(GO:0016580)
0.6 3.8 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.5 12.8 GO:0002080 acrosomal membrane(GO:0002080)
0.5 4.6 GO:0001739 sex chromatin(GO:0001739)
0.4 14.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 3.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.4 4.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.4 4.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3 17.5 GO:0031941 filamentous actin(GO:0031941)
0.3 3.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 4.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.3 8.1 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.2 1.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 8.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 10.7 GO:0043034 costamere(GO:0043034)
0.2 4.0 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 2.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.2 18.6 GO:0005604 basement membrane(GO:0005604)
0.2 10.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 8.0 GO:0008180 COP9 signalosome(GO:0008180)
0.2 8.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 9.3 GO:0031201 SNARE complex(GO:0031201)
0.1 11.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 5.3 GO:1990391 DNA repair complex(GO:1990391)
0.1 11.1 GO:0005884 actin filament(GO:0005884)
0.1 6.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 4.5 GO:0005581 collagen trimer(GO:0005581)
0.1 2.8 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 6.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.1 GO:0032433 filopodium tip(GO:0032433)
0.1 0.5 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 10.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 3.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 21.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 4.2 GO:0005902 microvillus(GO:0005902)
0.1 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 3.1 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.1 1.8 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.1 4.2 GO:0030315 T-tubule(GO:0030315)
0.1 1.8 GO:0005635 nuclear envelope(GO:0005635)
0.1 3.7 GO:0043195 terminal bouton(GO:0043195)
0.1 4.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 9.5 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 4.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 2.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 7.7 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 3.2 GO:0016607 nuclear speck(GO:0016607)
0.0 3.6 GO:0001650 fibrillar center(GO:0001650)
0.0 1.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.1 GO:0005874 microtubule(GO:0005874)
0.0 2.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 10.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 3.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.4 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
3.1 21.6 GO:0004849 uridine kinase activity(GO:0004849)
2.3 6.9 GO:0001069 regulatory region RNA binding(GO:0001069)
2.0 8.1 GO:0038025 glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
1.7 8.4 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
1.5 10.7 GO:0050815 phosphoserine binding(GO:0050815)
1.5 5.8 GO:0032143 single thymine insertion binding(GO:0032143)
1.4 4.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.3 17.8 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
1.2 3.7 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
1.1 5.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
1.0 10.7 GO:0002151 G-quadruplex RNA binding(GO:0002151) RNA strand annealing activity(GO:0033592)
0.8 4.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.7 2.8 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.7 10.7 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.6 18.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.6 11.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.6 3.5 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.6 10.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.5 2.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.5 4.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.4 4.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.4 15.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.4 12.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.4 1.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.4 1.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.4 6.4 GO:0048156 tau protein binding(GO:0048156)
0.3 4.0 GO:0031386 protein tag(GO:0031386)
0.3 1.0 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 5.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.3 9.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 4.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.3 4.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.3 0.5 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.3 6.5 GO:0017166 vinculin binding(GO:0017166)
0.3 4.1 GO:0045499 chemorepellent activity(GO:0045499)
0.2 5.7 GO:0070403 NAD+ binding(GO:0070403)
0.2 10.3 GO:0019894 kinesin binding(GO:0019894)
0.2 4.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.2 1.9 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 3.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 5.4 GO:0070064 proline-rich region binding(GO:0070064)
0.2 16.8 GO:0032947 protein complex scaffold(GO:0032947)
0.2 2.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 8.2 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.2 4.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 1.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 3.7 GO:0071837 HMG box domain binding(GO:0071837)
0.2 1.5 GO:0050693 LBD domain binding(GO:0050693)
0.1 8.2 GO:0070888 E-box binding(GO:0070888)
0.1 4.2 GO:0070410 co-SMAD binding(GO:0070410)
0.1 3.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 1.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 17.2 GO:0005178 integrin binding(GO:0005178)
0.1 1.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 3.9 GO:0042056 chemoattractant activity(GO:0042056)
0.1 4.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 2.2 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 8.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 9.5 GO:0005179 hormone activity(GO:0005179)
0.1 0.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 7.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 2.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.2 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 6.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.0 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0008142 transcription corepressor binding(GO:0001222) oxysterol binding(GO:0008142)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 2.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 8.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 2.3 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 2.7 GO:0008201 heparin binding(GO:0008201)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 1.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 18.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4 18.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.3 5.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 16.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.3 23.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.2 4.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 14.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 11.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 1.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 11.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 7.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 8.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 9.9 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.2 4.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 7.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 3.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 3.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 5.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 4.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 2.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 2.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 6.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 18.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.7 25.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.6 19.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.5 12.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.4 16.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 8.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 4.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 2.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2 3.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.2 5.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 3.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 10.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.2 5.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 18.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 3.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 3.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 6.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.0 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 1.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 8.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 4.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 2.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 8.4 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 3.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 5.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 2.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 4.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 2.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions