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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for CEBPA

Z-value: 1.42

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Transcription factors associated with CEBPA

Gene Symbol Gene ID Gene Info
ENSG00000245848.2 CCAAT enhancer binding protein alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPAhg19_v2_chr19_-_33793430_337934700.613.1e-23Click!

Activity profile of CEBPA motif

Sorted Z-values of CEBPA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_69742121 41.01 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
lysozyme
chr20_-_43883197 39.77 ENST00000338380.2
secretory leukocyte peptidase inhibitor
chr6_-_32557610 32.18 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr9_+_130911770 27.71 ENST00000372998.1
lipocalin 2
chr9_+_130911723 26.64 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
lipocalin 2
chr17_+_1665345 21.00 ENST00000576406.1
ENST00000571149.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_-_10007448 20.36 ENST00000538152.1
C-type lectin domain family 2, member B
chr10_-_21786179 19.11 ENST00000377113.5
cancer susceptibility candidate 10
chr19_-_6720686 17.79 ENST00000245907.6
complement component 3
chr8_-_6837602 17.17 ENST00000382692.2
defensin, alpha 1
chr11_-_5271122 17.06 ENST00000330597.3
hemoglobin, gamma A
chr1_+_196621156 16.37 ENST00000359637.2
complement factor H
chr1_+_196621002 16.12 ENST00000367429.4
ENST00000439155.2
complement factor H
chr16_+_72088376 15.80 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
haptoglobin
haptoglobin-related protein
chr1_-_153348067 15.46 ENST00000368737.3
S100 calcium binding protein A12
chr21_-_46348694 14.92 ENST00000355153.4
ENST00000397850.2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_+_22963158 14.63 ENST00000438241.1
complement component 1, q subcomponent, A chain
chr14_+_95078714 14.55 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_-_123201337 14.39 ENST00000528880.2
hydroxycarboxylic acid receptor 3
chr12_-_91573249 14.39 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr8_-_6875778 13.78 ENST00000535841.1
ENST00000327857.2
defensin, alpha 1B
defensin, alpha 3, neutrophil-specific
chr12_-_7656357 13.03 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
CD163 molecule
chr17_-_7017968 12.86 ENST00000355035.5
asialoglycoprotein receptor 2
chr17_+_20059302 12.46 ENST00000395530.2
sperm antigen with calponin homology and coiled-coil domains 1
chr4_-_185747188 12.39 ENST00000507295.1
ENST00000504900.1
ENST00000281455.2
ENST00000454703.2
acyl-CoA synthetase long-chain family member 1
chr12_+_7167980 12.36 ENST00000360817.5
ENST00000402681.3
complement component 1, s subcomponent
chr8_+_12808834 12.27 ENST00000400069.3
KIAA1456
chr10_+_5005598 12.07 ENST00000442997.1
aldo-keto reductase family 1, member C1
chr12_-_123187890 12.02 ENST00000328880.5
hydroxycarboxylic acid receptor 2
chr11_-_10590118 11.97 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr2_+_90060377 11.95 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr17_+_1665253 11.94 ENST00000254722.4
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_-_7018128 11.84 ENST00000380952.2
ENST00000254850.7
asialoglycoprotein receptor 2
chr11_-_33913708 11.55 ENST00000257818.2
LIM domain only 2 (rhombotin-like 1)
chr19_-_37019562 11.52 ENST00000523638.1
zinc finger protein 260
chr14_-_23285011 11.49 ENST00000397532.3
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr12_-_91572278 11.17 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
decorin
chr6_+_30457244 10.70 ENST00000376630.4
major histocompatibility complex, class I, E
chr4_-_100242549 10.68 ENST00000305046.8
ENST00000394887.3
alcohol dehydrogenase 1B (class I), beta polypeptide
chrX_-_47489244 10.43 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
complement factor properdin
chr6_+_31895467 10.39 ENST00000556679.1
ENST00000456570.1
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr10_+_5005445 10.15 ENST00000380872.4
aldo-keto reductase family 1, member C1
chr6_-_32920794 10.13 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr3_-_46249878 9.85 ENST00000296140.3
chemokine (C-C motif) receptor 1
chr10_-_70092671 9.72 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
phenazine biosynthesis-like protein domain containing
chr16_-_55866997 9.64 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chr19_-_40971667 9.60 ENST00000263368.4
biliverdin reductase B (flavin reductase (NADPH))
chr14_-_23285069 9.55 ENST00000554758.1
ENST00000397528.4
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_+_111415757 9.54 ENST00000429072.2
ENST00000271324.5
CD53 molecule
chr2_-_43453734 9.34 ENST00000282388.3
ZFP36 ring finger protein-like 2
chr4_-_155533787 9.28 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
fibrinogen gamma chain
chr11_-_59633951 9.17 ENST00000257264.3
transcobalamin I (vitamin B12 binding protein, R binder family)
chr2_+_102721023 8.94 ENST00000409589.1
ENST00000409329.1
interleukin 1 receptor, type I
chr17_+_56315936 8.87 ENST00000543544.1
lactoperoxidase
chr11_+_60050026 8.82 ENST00000395016.3
membrane-spanning 4-domains, subfamily A, member 4A
chr12_-_12491608 8.80 ENST00000545735.1
MANSC domain containing 1
chr6_-_133055815 8.44 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
vanin 3
chr19_-_40971643 8.43 ENST00000595483.1
biliverdin reductase B (flavin reductase (NADPH))
chr10_-_45474237 8.32 ENST00000448778.1
ENST00000298295.3
chromosome 10 open reading frame 10
chr10_+_97515409 8.27 ENST00000371207.3
ENST00000543964.1
ectonucleoside triphosphate diphosphohydrolase 1
chr17_-_34625719 8.21 ENST00000422211.2
ENST00000542124.1
chemokine (C-C motif) ligand 3-like 1
chr3_+_46395219 8.19 ENST00000445132.2
ENST00000292301.4
chemokine (C-C motif) receptor 2
chr12_-_96390063 7.97 ENST00000541929.1
histidine ammonia-lyase
chr11_-_10590238 7.84 ENST00000256178.3
lymphatic vessel endothelial hyaluronan receptor 1
chr19_+_56652556 7.76 ENST00000337080.3
zinc finger protein 444
chr6_-_33037019 7.66 ENST00000437811.1
major histocompatibility complex, class II, DP alpha 1
chr5_-_180229833 7.62 ENST00000307826.4
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr11_-_104972158 7.60 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr15_-_64648273 7.57 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
casein kinase 1, gamma 1
chr11_-_64510409 7.46 ENST00000394429.1
ENST00000394428.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_6983550 7.45 ENST00000576617.1
ENST00000416562.2
C-type lectin domain family 10, member A
chr20_+_56136136 7.39 ENST00000319441.4
ENST00000543666.1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr8_-_6795823 7.31 ENST00000297435.2
defensin, alpha 4, corticostatin
chr1_+_171154347 7.20 ENST00000209929.7
ENST00000441535.1
flavin containing monooxygenase 2 (non-functional)
chr3_+_186330712 7.13 ENST00000411641.2
ENST00000273784.5
alpha-2-HS-glycoprotein
chr1_+_111770232 7.10 ENST00000369744.2
chitinase 3-like 2
chr3_+_186435137 7.09 ENST00000447445.1
kininogen 1
chr1_+_111770278 7.06 ENST00000369748.4
chitinase 3-like 2
chr5_+_49963239 6.92 ENST00000505554.1
poly (ADP-ribose) polymerase family, member 8
chr4_+_74606223 6.89 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr1_-_153029980 6.77 ENST00000392653.2
small proline-rich protein 2A
chr14_-_92414055 6.75 ENST00000342058.4
fibulin 5
chr5_-_39219705 6.74 ENST00000351578.6
FYN binding protein
chr3_+_186435065 6.74 ENST00000287611.2
ENST00000265023.4
kininogen 1
chr16_+_56965960 6.70 ENST00000439977.2
ENST00000344114.4
ENST00000300302.5
ENST00000379792.2
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr6_+_31895480 6.68 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr17_-_66951474 6.68 ENST00000269080.2
ATP-binding cassette, sub-family A (ABC1), member 8
chr17_-_6983594 6.65 ENST00000571664.1
ENST00000254868.4
C-type lectin domain family 10, member A
chr5_+_170736243 6.62 ENST00000296921.5
T-cell leukemia homeobox 3
chrX_+_12924732 6.55 ENST00000218032.6
ENST00000311912.5
toll-like receptor 8
chr9_+_125137565 6.49 ENST00000373698.5
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr16_+_2587965 6.48 ENST00000342085.4
ENST00000566659.1
3-phosphoinositide dependent protein kinase-1
chr2_-_21266935 6.48 ENST00000233242.1
apolipoprotein B
chr20_+_46130671 6.45 ENST00000371998.3
ENST00000371997.3
nuclear receptor coactivator 3
chr10_+_114133773 6.41 ENST00000354655.4
acyl-CoA synthetase long-chain family member 5
chr17_+_56315787 6.33 ENST00000262290.4
ENST00000421678.2
lactoperoxidase
chr6_-_133055896 6.23 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
vanin 3
chr6_+_150920999 6.23 ENST00000367328.1
ENST00000367326.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr19_+_840963 6.20 ENST00000234347.5
proteinase 3
chr2_-_175462456 6.13 ENST00000409891.1
ENST00000410117.1
WAS/WASL interacting protein family, member 1
chr17_-_2415169 6.12 ENST00000263092.6
ENST00000538844.1
ENST00000576976.1
methyltransferase like 16
chr3_+_157154578 6.11 ENST00000295927.3
pentraxin 3, long
chr19_-_48389651 6.07 ENST00000222002.3
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr1_+_245133278 6.05 ENST00000366522.2
EF-hand calcium binding domain 2
chr12_-_10251576 6.03 ENST00000315330.4
C-type lectin domain family 1, member A
chr3_-_151047327 5.97 ENST00000325602.5
purinergic receptor P2Y, G-protein coupled, 13
chr19_-_54876558 5.96 ENST00000391742.2
ENST00000434277.2
leukocyte-associated immunoglobulin-like receptor 1
chr17_-_4167142 5.95 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ankyrin repeat and FYVE domain containing 1
chr6_-_49712147 5.93 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr14_+_21423611 5.91 ENST00000304625.2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr8_+_27348649 5.83 ENST00000521780.1
ENST00000380476.3
ENST00000518379.1
ENST00000521684.1
epoxide hydrolase 2, cytoplasmic
chr1_+_117297007 5.83 ENST00000369478.3
ENST00000369477.1
CD2 molecule
chr19_+_852291 5.79 ENST00000263621.1
elastase, neutrophil expressed
chr12_-_10251603 5.79 ENST00000457018.2
C-type lectin domain family 1, member A
chr5_-_39219641 5.78 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYN binding protein
chr18_+_61554932 5.77 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr6_+_106534192 5.75 ENST00000369091.2
ENST00000369096.4
PR domain containing 1, with ZNF domain
chr3_+_40498783 5.72 ENST00000338970.6
ENST00000396203.2
ENST00000416518.1
ribosomal protein L14
chrX_+_16668278 5.70 ENST00000380200.3
S100 calcium binding protein G
chr2_-_175462934 5.65 ENST00000392546.2
ENST00000436221.1
WAS/WASL interacting protein family, member 1
chr20_+_46130619 5.63 ENST00000372004.3
nuclear receptor coactivator 3
chr20_+_46130601 5.61 ENST00000341724.6
nuclear receptor coactivator 3
chr19_+_49258775 5.57 ENST00000593756.1
fibroblast growth factor 21
chr6_+_31895254 5.52 ENST00000299367.5
ENST00000442278.2
complement component 2
chr12_-_96390108 5.51 ENST00000538703.1
ENST00000261208.3
histidine ammonia-lyase
chr12_+_54674482 5.50 ENST00000547708.1
ENST00000340913.6
ENST00000551702.1
ENST00000330752.8
ENST00000547276.1
heterogeneous nuclear ribonucleoprotein A1
chr2_+_163200598 5.50 ENST00000437150.2
ENST00000453113.2
grancalcin, EF-hand calcium binding protein
chr11_+_60048053 5.50 ENST00000337908.4
membrane-spanning 4-domains, subfamily A, member 4A
chr4_+_71296204 5.44 ENST00000413702.1
mucin 7, secreted
chr5_-_64920115 5.44 ENST00000381018.3
ENST00000274327.7
tripartite motif containing 23
chr11_-_18258342 5.42 ENST00000278222.4
serum amyloid A4, constitutive
chr5_-_130970723 5.38 ENST00000308008.6
ENST00000296859.6
ENST00000507093.1
ENST00000510071.1
ENST00000509018.1
ENST00000307984.5
Rap guanine nucleotide exchange factor (GEF) 6
chr16_+_2588012 5.38 ENST00000354836.5
ENST00000389224.3
3-phosphoinositide dependent protein kinase-1
chr3_+_48264816 5.35 ENST00000296435.2
ENST00000576243.1
cathelicidin antimicrobial peptide
chr11_+_116700614 5.33 ENST00000375345.1
apolipoprotein C-III
chr1_-_186649543 5.31 ENST00000367468.5
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chrX_+_15767971 5.24 ENST00000479740.1
ENST00000454127.2
carbonic anhydrase VB, mitochondrial
chr19_+_55014085 5.22 ENST00000351841.2
leukocyte-associated immunoglobulin-like receptor 2
chr1_+_101185290 5.21 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
vascular cell adhesion molecule 1
chr1_-_200992827 5.21 ENST00000332129.2
ENST00000422435.2
kinesin family member 21B
chr4_+_159593418 5.18 ENST00000507475.1
ENST00000307738.5
electron-transferring-flavoprotein dehydrogenase
chr12_-_114841703 5.17 ENST00000526441.1
T-box 5
chr2_-_211179883 5.16 ENST00000352451.3
myosin, light chain 1, alkali; skeletal, fast
chr11_+_116700600 5.12 ENST00000227667.3
apolipoprotein C-III
chr11_+_67806467 5.12 ENST00000265686.3
ENST00000524598.1
ENST00000529657.1
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
chr15_+_58430368 5.08 ENST00000558772.1
ENST00000219919.4
aquaporin 9
chr17_-_34524157 4.99 ENST00000378354.4
ENST00000394484.1
chemokine (C-C motif) ligand 3-like 3
chr20_-_1600642 4.98 ENST00000381603.3
ENST00000381605.4
ENST00000279477.7
ENST00000568365.1
ENST00000564763.1
signal-regulatory protein beta 1
Uncharacterized protein
chr10_+_26727125 4.95 ENST00000376236.4
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr6_-_49712123 4.94 ENST00000263045.4
cysteine-rich secretory protein 3
chr3_+_10857885 4.94 ENST00000254488.2
ENST00000454147.1
solute carrier family 6 (neurotransmitter transporter), member 11
chr1_-_92952433 4.91 ENST00000294702.5
growth factor independent 1 transcription repressor
chr22_+_35776828 4.86 ENST00000216117.8
heme oxygenase (decycling) 1
chr1_+_196743912 4.83 ENST00000367425.4
complement factor H-related 3
chr12_-_71551868 4.80 ENST00000247829.3
tetraspanin 8
chr11_+_59824060 4.76 ENST00000395032.2
ENST00000358152.2
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr19_+_55014013 4.73 ENST00000301202.2
leukocyte-associated immunoglobulin-like receptor 2
chr22_-_30901637 4.73 ENST00000381982.3
ENST00000255858.7
ENST00000540456.1
ENST00000392772.2
SEC14-like 4 (S. cerevisiae)
chr10_+_17270214 4.69 ENST00000544301.1
vimentin
chr11_+_60048129 4.63 ENST00000355131.3
membrane-spanning 4-domains, subfamily A, member 4A
chr6_-_27782548 4.59 ENST00000333151.3
histone cluster 1, H2aj
chr19_+_6887571 4.59 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
egf-like module containing, mucin-like, hormone receptor-like 1
chr6_+_27782788 4.54 ENST00000359465.4
histone cluster 1, H2bm
chrX_+_15518923 4.50 ENST00000348343.6
BMX non-receptor tyrosine kinase
chr13_-_72441315 4.43 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
dachshund homolog 1 (Drosophila)
chr3_-_49726486 4.43 ENST00000449682.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr13_-_46679185 4.41 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr3_-_194072019 4.41 ENST00000429275.1
ENST00000323830.3
carboxypeptidase N, polypeptide 2
chr5_-_159739532 4.36 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
cyclin J-like
chr1_+_207277590 4.30 ENST00000367070.3
complement component 4 binding protein, alpha
chr13_-_46679144 4.30 ENST00000181383.4
carboxypeptidase B2 (plasma)
chr11_+_59824127 4.29 ENST00000278865.3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr6_+_117002339 4.25 ENST00000413340.1
ENST00000368564.1
ENST00000356348.1
karyopherin alpha 5 (importin alpha 6)
chr4_-_186877502 4.24 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
sorbin and SH3 domain containing 2
chr11_-_104905840 4.24 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr1_-_153321301 4.23 ENST00000368739.3
peptidoglycan recognition protein 4
chr1_-_163172625 4.21 ENST00000527988.1
ENST00000531476.1
ENST00000530507.1
regulator of G-protein signaling 5
chr12_-_110434096 4.20 ENST00000320063.9
ENST00000457474.2
ENST00000547815.1
ENST00000361006.5
G protein-coupled receptor kinase interacting ArfGAP 2
chr4_-_119274121 4.16 ENST00000296498.3
protease, serine, 12 (neurotrypsin, motopsin)
chr5_+_49962772 4.13 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
poly (ADP-ribose) polymerase family, member 8
chr9_+_33290491 4.11 ENST00000379540.3
ENST00000379521.4
ENST00000318524.6
nuclear transcription factor, X-box binding 1
chr13_-_33112956 4.11 ENST00000505213.1
NEDD4 binding protein 2-like 2
chr6_+_29910301 4.11 ENST00000376809.5
ENST00000376802.2
major histocompatibility complex, class I, A
chr10_+_114710516 4.00 ENST00000542695.1
ENST00000346198.4
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_+_89999259 3.98 ENST00000558026.1
immunoglobulin kappa variable 2D-28
chr2_+_71693812 3.96 ENST00000409651.1
ENST00000394120.2
ENST00000409744.1
ENST00000409366.1
ENST00000410020.3
ENST00000410041.1
dysferlin
chr13_-_99667960 3.95 ENST00000448493.2
dedicator of cytokinesis 9
chr16_+_82090028 3.87 ENST00000568090.1
hydroxysteroid (17-beta) dehydrogenase 2
chr11_-_130786400 3.83 ENST00000265909.4
sorting nexin 19
chr12_-_110434021 3.80 ENST00000355312.3
ENST00000551209.1
ENST00000550186.1
G protein-coupled receptor kinase interacting ArfGAP 2
chr1_+_209941827 3.80 ENST00000367023.1
TRAF3 interacting protein 3
chr14_+_22446680 3.79 ENST00000390443.3
T cell receptor alpha variable 8-6
chr3_-_158450231 3.77 ENST00000479756.1
retinoic acid receptor responder (tazarotene induced) 1
chr18_-_28622774 3.75 ENST00000434452.1
desmocollin 3
chr22_-_22307199 3.73 ENST00000397495.4
ENST00000263212.5
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr18_-_28622699 3.71 ENST00000360428.4
desmocollin 3
chr1_+_119957554 3.71 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr1_+_209941942 3.71 ENST00000487271.1
ENST00000477431.1
TRAF3 interacting protein 3
chr11_-_18270182 3.69 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
serum amyloid A2
chr10_-_70092635 3.68 ENST00000309049.4
phenazine biosynthesis-like protein domain containing

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.9 54.3 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
8.5 42.3 GO:0002399 MHC class II protein complex assembly(GO:0002399)
8.4 42.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
6.6 32.9 GO:0071279 cellular response to cobalt ion(GO:0071279)
5.9 17.8 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
5.7 17.2 GO:0035915 pore formation in membrane of other organism(GO:0035915)
5.3 15.8 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
4.5 13.5 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
3.6 10.7 GO:0032759 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
3.5 14.1 GO:1904640 response to methionine(GO:1904640)
3.5 21.0 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
3.5 10.4 GO:2000910 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
3.3 13.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
3.2 22.2 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
3.0 8.9 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
3.0 11.8 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
2.7 8.2 GO:2000439 negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
2.7 62.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
2.5 17.7 GO:0035624 receptor transactivation(GO:0035624)
2.4 12.0 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
2.2 8.7 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.1 12.4 GO:0034201 response to oleic acid(GO:0034201)
2.0 24.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.9 7.6 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
1.8 5.3 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.7 5.2 GO:0003218 cardiac left ventricle formation(GO:0003218)
1.7 5.1 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
1.7 25.4 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.7 77.9 GO:0019731 antibacterial humoral response(GO:0019731)
1.6 6.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
1.6 6.6 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
1.6 4.9 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
1.6 17.7 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.6 6.3 GO:0051552 flavone metabolic process(GO:0051552)
1.6 9.3 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
1.5 15.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.5 6.1 GO:0044793 negative regulation by host of viral process(GO:0044793)
1.5 5.8 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
1.4 4.2 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
1.4 5.5 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
1.4 12.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
1.3 3.8 GO:1990502 dense core granule maturation(GO:1990502)
1.2 3.7 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
1.2 6.1 GO:0080009 mRNA methylation(GO:0080009)
1.2 3.6 GO:0006711 estrogen catabolic process(GO:0006711)
1.2 5.8 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
1.2 5.8 GO:0033078 extrathymic T cell differentiation(GO:0033078)
1.1 3.4 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
1.1 17.1 GO:0015671 oxygen transport(GO:0015671)
1.1 3.4 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
1.1 3.3 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
1.1 2.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.1 3.2 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
1.0 13.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.0 6.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
1.0 5.1 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
1.0 10.1 GO:0006069 ethanol oxidation(GO:0006069)
1.0 8.0 GO:0070995 NADPH oxidation(GO:0070995)
1.0 3.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
1.0 6.0 GO:0048549 positive regulation of pinocytosis(GO:0048549)
1.0 6.9 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
1.0 9.6 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
1.0 2.9 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.9 3.8 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.9 3.8 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.9 6.5 GO:0010269 response to selenium ion(GO:0010269)
0.9 2.8 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.9 9.2 GO:0015889 cobalamin transport(GO:0015889)
0.9 2.7 GO:2001248 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.9 2.7 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.9 5.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.9 14.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.9 3.4 GO:0035425 autocrine signaling(GO:0035425)
0.8 20.0 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.8 14.9 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.8 2.5 GO:1903487 regulation of lactation(GO:1903487)
0.8 1.6 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.8 23.1 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.8 2.3 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.8 2.3 GO:0002384 hepatic immune response(GO:0002384)
0.7 6.7 GO:0042908 xenobiotic transport(GO:0042908)
0.7 4.3 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.7 3.5 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.7 6.3 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.7 2.7 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.7 19.8 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.7 7.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.7 3.4 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.7 4.0 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.6 15.5 GO:0050832 defense response to fungus(GO:0050832)
0.6 2.5 GO:0036343 psychomotor behavior(GO:0036343)
0.6 5.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.6 4.5 GO:0001865 NK T cell differentiation(GO:0001865)
0.6 1.7 GO:0097052 tryptophan catabolic process to acetyl-CoA(GO:0019442) L-kynurenine metabolic process(GO:0097052)
0.6 12.8 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.6 4.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.6 14.9 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.5 3.8 GO:0019532 oxalate transport(GO:0019532)
0.5 1.6 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.5 1.6 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.5 3.1 GO:0071321 positive regulation of oocyte development(GO:0060282) cellular response to cGMP(GO:0071321)
0.5 8.3 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.5 4.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.5 1.5 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.5 11.6 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.5 4.9 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.5 9.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.5 2.3 GO:1900920 regulation of amino acid import(GO:0010958) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.5 0.5 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.5 23.8 GO:0006953 acute-phase response(GO:0006953)
0.5 16.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.4 7.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.4 3.5 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.4 6.6 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.4 4.3 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.4 24.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.4 2.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.4 3.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.4 7.5 GO:0006068 ethanol metabolic process(GO:0006067) ethanol catabolic process(GO:0006068)
0.4 3.7 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.4 3.0 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.4 5.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.4 5.8 GO:0042730 fibrinolysis(GO:0042730)
0.4 2.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.4 14.7 GO:0010039 response to iron ion(GO:0010039)
0.3 2.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.3 0.7 GO:0032730 positive regulation of interleukin-1 alpha production(GO:0032730)
0.3 5.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.3 2.7 GO:0000075 cell cycle checkpoint(GO:0000075)
0.3 1.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.3 4.0 GO:0001778 plasma membrane repair(GO:0001778)
0.3 2.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.3 4.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 3.7 GO:0006702 androgen biosynthetic process(GO:0006702)
0.3 7.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 3.6 GO:0046415 urate metabolic process(GO:0046415)
0.3 1.8 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.3 6.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.3 10.4 GO:0003341 cilium movement(GO:0003341)
0.3 11.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.3 6.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.3 2.8 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475)
0.3 7.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.3 8.1 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.3 3.3 GO:0070307 lens fiber cell development(GO:0070307)
0.3 5.4 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.3 2.7 GO:0032264 IMP salvage(GO:0032264)
0.3 3.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.3 3.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 3.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 2.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 1.6 GO:0072501 cellular divalent inorganic anion homeostasis(GO:0072501)
0.2 0.9 GO:0050705 regulation of interleukin-1 alpha secretion(GO:0050705)
0.2 0.2 GO:0043379 memory T cell differentiation(GO:0043379)
0.2 1.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 0.4 GO:0050955 thermoception(GO:0050955)
0.2 1.9 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 1.6 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 14.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 0.8 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.2 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.2 2.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 1.8 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 1.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 1.9 GO:0044804 nucleophagy(GO:0044804)
0.2 4.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 1.6 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.5 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 2.0 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 1.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 0.7 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177) positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.2 0.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 3.0 GO:0001502 cartilage condensation(GO:0001502)
0.1 14.0 GO:2000257 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.1 1.0 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 0.7 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 2.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 5.2 GO:0015701 bicarbonate transport(GO:0015701)
0.1 2.5 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 3.0 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.1 2.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 1.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.4 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.3 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 7.5 GO:0006342 chromatin silencing(GO:0006342)
0.1 5.0 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.1 11.3 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.3 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 5.2 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.3 GO:0015747 urate transport(GO:0015747)
0.1 5.7 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.5 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 7.3 GO:0070268 cornification(GO:0070268)
0.1 3.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 2.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 2.0 GO:0060119 inner ear receptor cell development(GO:0060119)
0.1 1.2 GO:0003334 keratinocyte development(GO:0003334)
0.1 4.5 GO:0007588 excretion(GO:0007588)
0.1 2.1 GO:0048477 oogenesis(GO:0048477)
0.1 3.5 GO:0060021 palate development(GO:0060021)
0.0 0.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 1.4 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 1.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 4.5 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.6 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 13.8 GO:0002250 adaptive immune response(GO:0002250)
0.0 2.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.7 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 4.3 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.4 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 5.5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.5 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.5 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.7 GO:0006825 copper ion transport(GO:0006825)
0.0 2.0 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 5.3 GO:0008360 regulation of cell shape(GO:0008360)
0.0 3.1 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.5 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.6 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 1.0 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 1.5 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 15.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 1.2 GO:0055001 muscle cell development(GO:0055001)
0.0 0.6 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 1.3 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733) t-circle formation(GO:0090656)
0.0 3.5 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 1.1 GO:0042552 myelination(GO:0042552)
0.0 0.6 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 1.6 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.5 GO:0061025 membrane fusion(GO:0061025)
0.0 0.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:0045921 positive regulation of exocytosis(GO:0045921)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 15.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
3.0 14.9 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
2.9 14.6 GO:0005602 complement component C1 complex(GO:0005602)
2.6 31.0 GO:0043203 axon hillock(GO:0043203)
2.4 50.0 GO:0042613 MHC class II protein complex(GO:0042613)
2.4 11.8 GO:0097179 protease inhibitor complex(GO:0097179)
2.1 12.9 GO:1990037 Lewy body core(GO:1990037)
2.1 16.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.9 177.2 GO:0035580 specific granule lumen(GO:0035580)
1.9 18.5 GO:0042611 MHC protein complex(GO:0042611)
1.8 25.6 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.8 5.4 GO:0097679 other organism cytoplasm(GO:0097679)
1.7 5.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
1.4 17.1 GO:0005833 hemoglobin complex(GO:0005833)
1.2 6.0 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.9 6.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.9 84.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.7 6.7 GO:0071953 elastic fiber(GO:0071953)
0.7 9.3 GO:0005577 fibrinogen complex(GO:0005577)
0.7 4.0 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.7 3.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.6 14.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.6 2.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.5 111.1 GO:0072562 blood microparticle(GO:0072562)
0.4 4.9 GO:0042101 T cell receptor complex(GO:0042101)
0.4 5.1 GO:0044327 dendritic spine head(GO:0044327)
0.4 3.7 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.4 1.6 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.4 1.6 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.3 2.4 GO:0036449 microtubule minus-end(GO:0036449)
0.3 6.6 GO:0036020 endolysosome membrane(GO:0036020)
0.3 3.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 4.2 GO:0043083 synaptic cleft(GO:0043083)
0.3 3.5 GO:0042788 polysomal ribosome(GO:0042788)
0.3 1.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 2.3 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 7.5 GO:0030057 desmosome(GO:0030057)
0.2 28.1 GO:0035579 specific granule membrane(GO:0035579)
0.2 1.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 0.9 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.2 12.3 GO:0000786 nucleosome(GO:0000786)
0.2 5.9 GO:0045178 basal part of cell(GO:0045178)
0.2 5.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 5.2 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2 4.6 GO:0001533 cornified envelope(GO:0001533)
0.2 2.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 5.2 GO:0005859 muscle myosin complex(GO:0005859)
0.2 0.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 1.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 13.0 GO:0043195 terminal bouton(GO:0043195)
0.1 11.5 GO:0005901 caveola(GO:0005901)
0.1 2.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 14.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 9.3 GO:0030139 endocytic vesicle(GO:0030139)
0.1 3.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 8.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.9 GO:0034707 chloride channel complex(GO:0034707)
0.1 31.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 2.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 10.9 GO:0043204 perikaryon(GO:0043204)
0.1 14.8 GO:0005884 actin filament(GO:0005884)
0.1 1.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 10.4 GO:0032587 ruffle membrane(GO:0032587)
0.1 13.0 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.1 1.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 15.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 7.3 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 4.6 GO:0005871 kinesin complex(GO:0005871)
0.1 7.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 4.5 GO:0030286 dynein complex(GO:0030286)
0.1 5.3 GO:0031901 early endosome membrane(GO:0031901)
0.1 2.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 4.2 GO:0044216 host(GO:0018995) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 1.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 19.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 2.0 GO:0000421 autophagosome membrane(GO:0000421)
0.1 3.5 GO:0005604 basement membrane(GO:0005604)
0.1 3.0 GO:0042383 sarcolemma(GO:0042383)
0.1 5.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 5.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 4.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 5.7 GO:0030018 Z disc(GO:0030018)
0.0 3.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 59.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 17.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 4.0 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 2.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 19.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.6 GO:0048786 presynaptic membrane(GO:0042734) presynaptic active zone(GO:0048786)
0.0 38.2 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 42.2 GO:0003796 lysozyme activity(GO:0003796)
6.5 26.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
4.5 18.0 GO:0004074 biliverdin reductase activity(GO:0004074)
4.0 11.9 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
3.4 13.5 GO:0016841 ammonia-lyase activity(GO:0016841)
3.1 24.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
3.0 11.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
2.9 14.7 GO:0017159 pantetheine hydrolase activity(GO:0017159)
2.7 8.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
2.6 15.8 GO:0030492 hemoglobin binding(GO:0030492)
2.6 10.4 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
2.5 7.4 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
2.5 12.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
2.2 8.9 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
2.1 14.9 GO:0030369 ICAM-3 receptor activity(GO:0030369)
2.0 6.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
1.9 9.6 GO:0004771 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
1.9 21.0 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
1.9 7.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.8 5.5 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
1.8 17.7 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
1.7 5.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
1.7 10.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.6 4.9 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
1.6 6.5 GO:0035473 lipase binding(GO:0035473)
1.6 58.4 GO:0042605 peptide antigen binding(GO:0042605)
1.6 17.1 GO:0005344 oxygen transporter activity(GO:0005344)
1.5 3.1 GO:0019862 IgA binding(GO:0019862)
1.4 4.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.4 9.7 GO:0050294 steroid sulfotransferase activity(GO:0050294)
1.3 32.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.3 5.1 GO:0015254 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
1.2 3.7 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
1.1 3.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
1.1 4.5 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
1.1 6.3 GO:1990254 keratin filament binding(GO:1990254)
1.0 3.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
1.0 5.9 GO:0004522 ribonuclease A activity(GO:0004522)
1.0 5.8 GO:0042577 lipid phosphatase activity(GO:0042577)
1.0 5.7 GO:0005499 vitamin D binding(GO:0005499)
0.9 2.7 GO:1902122 bile acid receptor activity(GO:0038181) chenodeoxycholic acid binding(GO:1902122)
0.9 8.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.9 95.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.8 11.8 GO:0050700 CARD domain binding(GO:0050700)
0.8 6.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.8 9.2 GO:0031419 cobalamin binding(GO:0031419)
0.8 14.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.8 1.6 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.8 3.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.8 15.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.8 2.3 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.8 9.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.7 23.1 GO:0001848 complement binding(GO:0001848)
0.7 4.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.7 5.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.6 17.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.6 3.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.6 18.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.6 3.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.6 3.6 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.6 8.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.6 1.2 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.5 1.6 GO:0003883 CTP synthase activity(GO:0003883)
0.5 5.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.5 1.5 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563) azole transmembrane transporter activity(GO:1901474)
0.5 8.7 GO:0005522 profilin binding(GO:0005522)
0.5 15.1 GO:0042056 chemoattractant activity(GO:0042056)
0.5 2.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 2.7 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.4 1.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.4 2.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.4 27.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 9.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.4 1.7 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.4 7.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.4 59.7 GO:0002020 protease binding(GO:0002020)
0.4 1.6 GO:0004998 transferrin receptor activity(GO:0004998)
0.4 3.9 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.4 3.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.4 20.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.4 10.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 11.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.4 3.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.3 1.0 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.3 6.6 GO:0043495 protein anchor(GO:0043495)
0.3 4.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 1.6 GO:0050436 microfibril binding(GO:0050436)
0.3 5.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 3.4 GO:0051525 NFAT protein binding(GO:0051525)
0.3 27.7 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.3 6.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3 9.5 GO:0001972 retinoic acid binding(GO:0001972)
0.3 2.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 2.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.3 10.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 1.5 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.3 0.9 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.3 2.8 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.3 15.2 GO:0004601 peroxidase activity(GO:0004601)
0.3 4.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.3 5.9 GO:0016722 oxidoreductase activity, oxidizing metal ions(GO:0016722)
0.3 0.8 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.3 2.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 3.5 GO:0008097 5S rRNA binding(GO:0008097)
0.2 56.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 0.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 2.9 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 5.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 11.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 7.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 0.4 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.2 2.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 0.9 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 2.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 0.5 GO:0017129 triglyceride binding(GO:0017129)
0.2 15.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 2.8 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.2 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.2 3.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 5.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 1.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 5.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 1.8 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 3.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 2.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.8 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.4 GO:0070403 NAD+ binding(GO:0070403)
0.1 4.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 30.5 GO:0030246 carbohydrate binding(GO:0030246)
0.1 3.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 8.4 GO:0019003 GDP binding(GO:0019003)
0.1 2.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 4.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 1.7 GO:0051400 BH domain binding(GO:0051400)
0.1 14.8 GO:0005178 integrin binding(GO:0005178)
0.1 2.3 GO:0042166 acetylcholine binding(GO:0042166)
0.1 0.7 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.3 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 2.0 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 2.3 GO:0051117 ATPase binding(GO:0051117)
0.1 0.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 13.3 GO:0044325 ion channel binding(GO:0044325)
0.1 6.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 4.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 6.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 2.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 8.0 GO:0003823 antigen binding(GO:0003823)
0.1 5.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 4.6 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.7 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 15.3 GO:0005096 GTPase activator activity(GO:0005096)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 22.7 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 7.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 1.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310) annealing activity(GO:0097617)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 2.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.3 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 35.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.9 46.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.7 22.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.7 33.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.6 15.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.6 39.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.5 9.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.4 54.9 PID CMYB PATHWAY C-MYB transcription factor network
0.4 11.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.4 95.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4 64.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 11.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.3 12.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.3 10.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 2.3 ST STAT3 PATHWAY STAT3 Pathway
0.3 9.6 PID RAS PATHWAY Regulation of Ras family activation
0.2 4.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 9.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 3.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 2.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 7.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 8.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 7.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 39.1 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1 1.8 ST GAQ PATHWAY G alpha q Pathway
0.1 2.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.4 PID CD40 PATHWAY CD40/CD40L signaling
0.1 7.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 3.3 PID AURORA A PATHWAY Aurora A signaling
0.1 4.0 PID AP1 PATHWAY AP-1 transcription factor network
0.1 6.1 PID E2F PATHWAY E2F transcription factor network
0.1 1.7 PID BCR 5PATHWAY BCR signaling pathway
0.1 4.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 5.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 3.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 0.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.0 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 64.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
2.6 46.4 REACTOME DEFENSINS Genes involved in Defensins
2.2 43.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.8 39.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.3 10.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.2 25.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.0 19.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.9 18.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.8 12.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.8 11.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.8 16.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.8 13.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.7 18.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.7 59.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.6 13.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.6 17.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.6 15.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.6 7.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.6 35.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.5 6.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.5 4.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.4 3.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 22.9 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.4 5.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 5.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 9.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 6.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 9.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.3 6.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.3 2.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 23.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.3 5.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 3.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.3 20.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.3 5.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 7.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 3.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 8.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 0.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 7.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 2.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 4.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.2 8.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.2 3.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 5.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 25.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 2.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 7.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 0.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 6.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 9.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 2.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 3.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 3.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 3.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 9.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 0.9 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 1.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 4.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 4.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 2.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.8 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.8 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway