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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for CREB1

Z-value: 1.91

Motif logo

Transcription factors associated with CREB1

Gene Symbol Gene ID Gene Info
ENSG00000118260.10 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREB1hg19_v2_chr2_+_208394794_2083948340.588.3e-21Click!

Activity profile of CREB1 motif

Sorted Z-values of CREB1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_17104356 102.06 ENST00000361272.4
ENST00000523917.1
CCR4-NOT transcription complex, subunit 7
chr6_-_43027105 54.33 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
mitochondrial ribosomal protein L2
chr3_+_45017722 53.21 ENST00000265564.7
exosome component 7
chr12_+_108079664 45.35 ENST00000541166.1
PWP1 homolog (S. cerevisiae)
chr1_-_53704157 43.08 ENST00000371466.4
ENST00000371470.3
mago-nashi homolog, proliferation-associated (Drosophila)
chr15_-_34394119 36.44 ENST00000256545.4
ER membrane protein complex subunit 7
chr6_-_31926208 36.25 ENST00000454913.1
ENST00000436289.2
negative elongation factor complex member E
chr14_+_105219437 35.13 ENST00000329967.6
ENST00000347067.5
ENST00000553810.1
SIVA1, apoptosis-inducing factor
chr12_+_132628963 34.09 ENST00000330579.1
nucleolar complex associated 4 homolog (S. cerevisiae)
chr12_+_69633372 32.36 ENST00000456847.3
ENST00000266679.8
cleavage and polyadenylation specific factor 6, 68kDa
chr6_-_31926629 31.13 ENST00000375425.5
ENST00000426722.1
ENST00000441998.1
ENST00000444811.2
ENST00000375429.3
negative elongation factor complex member E
chrX_-_153285395 30.17 ENST00000369980.3
interleukin-1 receptor-associated kinase 1
chr15_-_34394008 29.93 ENST00000527822.1
ENST00000528949.1
ER membrane protein complex subunit 7
chr3_-_53290016 29.24 ENST00000423525.2
ENST00000423516.1
ENST00000296289.6
ENST00000462138.1
transketolase
chr17_+_8152590 28.29 ENST00000584044.1
ENST00000314666.6
ENST00000545834.1
ENST00000581242.1
phosphoribosylformylglycinamidine synthase
chr1_-_145827015 27.75 ENST00000534502.1
ENST00000313835.9
ENST00000454423.3
G protein-coupled receptor 89A
chr9_+_70856899 26.53 ENST00000377342.5
ENST00000478048.1
COBW domain containing 3
chr6_-_31774714 26.38 ENST00000375661.5
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_-_685559 26.03 ENST00000301329.6
glyoxalase domain containing 4
chr2_-_29093132 25.94 ENST00000306108.5
tRNA methyltransferase 61 homolog B (S. cerevisiae)
chr14_+_23776167 25.83 ENST00000554635.1
ENST00000557008.1
BCL2-like 2
BCL2L2-PABPN1 readthrough
chr9_-_69262509 25.81 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
COBW domain containing 6
chr9_-_179018 25.74 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
COBW domain containing 1
chr11_-_62607036 25.64 ENST00000311713.7
ENST00000278856.4
WD repeat domain 74
chr12_-_124118296 25.59 ENST00000424014.2
ENST00000537073.1
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
chr1_-_229644034 25.36 ENST00000366678.3
ENST00000261396.3
ENST00000537506.1
nucleoporin 133kDa
chr14_+_23776024 24.90 ENST00000553781.1
ENST00000556100.1
ENST00000557236.1
ENST00000557579.1
BCL2L2-PABPN1 readthrough
BCL2-like 2
chr19_+_10362577 24.83 ENST00000592514.1
ENST00000307422.5
ENST00000253099.6
ENST00000590150.1
ENST00000590669.1
mitochondrial ribosomal protein L4
chr2_-_68290106 24.64 ENST00000407324.1
ENST00000355848.3
ENST00000409302.1
ENST00000410067.3
C1D nuclear receptor corepressor
chr11_+_60609537 24.60 ENST00000227520.5
coiled-coil domain containing 86
chr2_+_114195268 24.55 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
COBW domain containing 2
chr3_+_141457030 24.47 ENST00000273480.3
ring finger protein 7
chr12_-_120884175 24.40 ENST00000546954.1
TP53 regulated inhibitor of apoptosis 1
chr17_-_685493 24.38 ENST00000536578.1
ENST00000301328.5
ENST00000576419.1
glyoxalase domain containing 4
chr3_-_196669298 23.77 ENST00000411704.1
ENST00000452404.2
nuclear cap binding protein subunit 2, 20kDa
chr15_-_66790146 23.76 ENST00000316634.5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr9_-_70490107 23.45 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
COBW domain containing 5
chr2_-_242626127 23.20 ENST00000445261.1
deoxythymidylate kinase (thymidylate kinase)
chr2_-_240964716 23.19 ENST00000404554.1
ENST00000407129.3
ENST00000307300.4
ENST00000443626.1
ENST00000252711.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr3_-_196669248 23.08 ENST00000447325.1
nuclear cap binding protein subunit 2, 20kDa
chr1_-_115259337 22.96 ENST00000369535.4
neuroblastoma RAS viral (v-ras) oncogene homolog
chr13_+_103249322 22.82 ENST00000376065.4
ENST00000376052.3
tripeptidyl peptidase II
chr17_+_57642886 22.28 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr9_-_32573130 22.07 ENST00000350021.2
ENST00000379847.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr12_+_69633407 21.87 ENST00000551516.1
cleavage and polyadenylation specific factor 6, 68kDa
chr4_+_113558272 21.68 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
La ribonucleoprotein domain family, member 7
chr22_+_20105259 21.64 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr16_-_3767506 21.21 ENST00000538171.1
TNF receptor-associated protein 1
chr17_+_73663402 21.13 ENST00000355423.3
SAP30 binding protein
chr1_+_147400506 20.51 ENST00000314163.7
ENST00000468618.2
G protein-coupled receptor 89B
chr17_-_47022140 20.32 ENST00000290330.3
SNF8, ESCRT-II complex subunit
chr9_+_70856397 20.30 ENST00000360171.6
COBW domain containing 3
chr3_-_52443799 20.22 ENST00000470173.1
ENST00000296288.5
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chrX_-_153285251 20.05 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
interleukin-1 receptor-associated kinase 1
chrX_-_47518498 19.86 ENST00000335890.2
ubiquitously-expressed, prefoldin-like chaperone
chr16_-_3767551 19.82 ENST00000246957.5
TNF receptor-associated protein 1
chr21_-_44527613 19.76 ENST00000380276.2
ENST00000398137.1
ENST00000291552.4
U2 small nuclear RNA auxiliary factor 1
chr11_-_126138808 19.74 ENST00000332118.6
ENST00000532259.1
signal recognition particle receptor (docking protein)
chr9_-_33001520 19.53 ENST00000463596.1
ENST00000379819.1
ENST00000397172.3
ENST00000379812.5
ENST00000477119.1
ENST00000379813.3
ENST00000379825.2
ENST00000309615.3
ENST00000476858.1
ENST00000473221.1
aprataxin
chr22_+_20105012 19.37 ENST00000331821.3
ENST00000411892.1
RAN binding protein 1
chr3_+_141457105 19.34 ENST00000480908.1
ENST00000393000.3
ring finger protein 7
chr12_+_7079944 19.21 ENST00000261406.6
EMG1 N1-specific pseudouridine methyltransferase
chr7_+_23145347 19.07 ENST00000322231.7
kelch-like family member 7
chr19_+_54619125 18.88 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
pre-mRNA processing factor 31
chrX_+_24072833 18.74 ENST00000253039.4
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr3_-_45017609 18.70 ENST00000342790.4
ENST00000424952.2
ENST00000296127.3
ENST00000455235.1
zinc finger, DHHC-type containing 3
chr12_-_58165870 18.64 ENST00000257848.7
methyltransferase like 1
chr6_-_144416737 18.19 ENST00000367569.2
splicing factor 3b, subunit 5, 10kDa
chrX_-_47518527 18.08 ENST00000333119.3
ubiquitously-expressed, prefoldin-like chaperone
chr1_-_36107445 17.93 ENST00000373237.3
proteasome (prosome, macropain) subunit, beta type, 2
chr4_-_39367949 17.80 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
replication factor C (activator 1) 1, 145kDa
chr7_+_23145366 17.79 ENST00000339077.5
ENST00000322275.5
ENST00000539124.1
ENST00000542558.1
kelch-like family member 7
chr17_+_73663470 17.76 ENST00000583536.1
SAP30 binding protein
chr19_+_10362882 17.73 ENST00000393733.2
ENST00000588502.1
mitochondrial ribosomal protein L4
chr5_-_133304473 17.55 ENST00000231512.3
chromosome 5 open reading frame 15
chr1_+_186344945 17.50 ENST00000419367.3
ENST00000287859.6
chromosome 1 open reading frame 27
chr1_+_186344883 17.26 ENST00000367470.3
chromosome 1 open reading frame 27
chr11_+_34127142 17.08 ENST00000257829.3
ENST00000531159.2
N-acetyltransferase 10 (GCN5-related)
chr12_+_108079509 17.03 ENST00000412830.3
ENST00000547995.1
PWP1 homolog (S. cerevisiae)
chr8_-_126103969 16.82 ENST00000517845.1
KIAA0196
chr15_+_80351910 16.77 ENST00000261749.6
ENST00000561060.1
zinc finger, AN1-type domain 6
chr1_-_220220000 16.76 ENST00000366923.3
glutamyl-prolyl-tRNA synthetase
chr12_-_46384334 16.67 ENST00000369367.3
ENST00000266589.6
ENST00000395453.2
ENST00000395454.2
SR-related CTD-associated factor 11
chr19_-_5719860 16.44 ENST00000590729.1
lon peptidase 1, mitochondrial
chr8_-_126104055 16.37 ENST00000318410.7
KIAA0196
chr16_-_20753114 15.96 ENST00000396083.2
THUMP domain containing 1
chr2_-_130939115 15.95 ENST00000441135.1
ENST00000339679.7
ENST00000426662.2
ENST00000443958.2
ENST00000351288.6
ENST00000453750.1
ENST00000452225.2
sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
chr20_+_55043647 15.90 ENST00000023939.4
ENST00000395881.3
ENST00000357348.5
ENST00000449062.1
ENST00000435342.2
replication termination factor 2 domain containing 1
chr15_+_80351977 15.86 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
zinc finger, AN1-type domain 6
chr2_-_3606206 15.75 ENST00000315212.3
ribonuclease H1
chr3_-_196669371 15.64 ENST00000427641.2
ENST00000321256.5
nuclear cap binding protein subunit 2, 20kDa
chr17_+_33914460 15.61 ENST00000537622.2
adaptor-related protein complex 2, beta 1 subunit
chr17_+_685513 15.17 ENST00000304478.4
RNA methyltransferase like 1
chr9_+_114393634 15.07 ENST00000556107.1
ENST00000374294.3
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr1_-_32110467 15.00 ENST00000440872.2
ENST00000373703.4
penta-EF-hand domain containing 1
chr7_+_23221613 14.99 ENST00000410002.3
ENST00000413919.1
nucleoporin like 2
chr17_+_33914276 14.99 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr8_+_101162812 14.98 ENST00000353107.3
ENST00000522439.1
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr4_+_122722466 14.85 ENST00000243498.5
ENST00000379663.3
ENST00000509800.1
exosome component 9
chr5_-_179233934 14.48 ENST00000292591.7
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr6_+_41755389 14.27 ENST00000398884.3
ENST00000398881.3
translocase of outer mitochondrial membrane 6 homolog (yeast)
chr17_+_40985407 14.14 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr9_-_134955246 13.94 ENST00000357028.2
ENST00000474263.1
ENST00000292035.5
mediator complex subunit 27
chr3_-_101405539 13.90 ENST00000469605.1
ENST00000495401.1
ENST00000394077.3
ribosomal protein L24
chr14_+_61447927 13.89 ENST00000451406.1
solute carrier family 38, member 6
chr22_+_26879817 13.82 ENST00000215917.7
SRR1 domain containing
chr7_+_23221438 13.61 ENST00000258742.5
nucleoporin like 2
chr11_-_66112555 13.53 ENST00000425825.2
ENST00000359957.3
breast cancer metastasis suppressor 1
chr8_+_133787586 13.50 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHD finger protein 20-like 1
chr6_-_34855773 13.46 ENST00000420584.2
ENST00000361288.4
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
chr4_-_74124502 13.44 ENST00000358602.4
ENST00000330838.6
ENST00000561029.1
ankyrin repeat domain 17
chr4_-_146019335 13.40 ENST00000451299.2
ENST00000507656.1
ENST00000309439.5
anaphase promoting complex subunit 10
chr16_+_19079215 13.10 ENST00000544894.2
ENST00000561858.1
coenzyme Q7 homolog, ubiquinone (yeast)
chr7_-_93633658 13.00 ENST00000433727.1
Bet1 golgi vesicular membrane trafficking protein
chr1_-_154600421 12.96 ENST00000368471.3
ENST00000292205.5
adenosine deaminase, RNA-specific
chr7_-_93633684 12.87 ENST00000222547.3
ENST00000425626.1
Bet1 golgi vesicular membrane trafficking protein
chr1_+_45241109 12.54 ENST00000396651.3
ribosomal protein S8
chr16_+_70380732 12.14 ENST00000302243.7
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
chr12_+_64173888 11.85 ENST00000537373.1
transmembrane protein 5
chr2_+_130939235 11.83 ENST00000425361.1
ENST00000457492.1
mitotic spindle organizing protein 2B
chr4_-_146019287 10.53 ENST00000502847.1
ENST00000513054.1
anaphase promoting complex subunit 10
chr11_+_57480046 10.41 ENST00000378312.4
ENST00000278422.4
thioredoxin-related transmembrane protein 2
chr16_+_1359511 10.17 ENST00000397514.3
ENST00000397515.2
ENST00000567383.1
ENST00000403747.2
ENST00000566587.1
ubiquitin-conjugating enzyme E2I
chr6_+_37400974 10.11 ENST00000455891.1
ENST00000373451.4
cap methyltransferase 1
chr1_+_45241186 10.08 ENST00000372209.3
ribosomal protein S8
chr19_-_19030157 10.02 ENST00000349893.4
ENST00000351079.4
ENST00000600932.1
ENST00000262812.4
coatomer protein complex, subunit epsilon
chr12_-_58240470 10.01 ENST00000548823.1
ENST00000398073.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr1_-_220219775 9.89 ENST00000609181.1
glutamyl-prolyl-tRNA synthetase
chr12_-_44200052 9.70 ENST00000548315.1
ENST00000552521.1
ENST00000546662.1
ENST00000548403.1
ENST00000546506.1
twinfilin actin-binding protein 1
chr9_+_140083099 9.64 ENST00000322310.5
Sjogren syndrome nuclear autoantigen 1
chr4_-_146019693 9.51 ENST00000514390.1
anaphase promoting complex subunit 10
chr4_-_4543700 9.45 ENST00000505286.1
ENST00000306200.2
syntaxin 18
chr8_-_145743164 9.30 ENST00000428558.2
RecQ protein-like 4
chr1_+_7831323 9.24 ENST00000054666.6
vesicle-associated membrane protein 3
chr12_+_64173583 8.82 ENST00000261234.6
transmembrane protein 5
chr16_-_2318373 8.79 ENST00000566458.1
ENST00000320225.5
RNA binding protein S1, serine-rich domain
chr6_-_114292284 8.77 ENST00000520895.1
ENST00000521163.1
ENST00000524334.1
ENST00000368632.2
ENST00000398283.2
histone deacetylase 2
chr20_-_5093503 8.71 ENST00000379277.2
transmembrane protein 230
chr11_-_62572901 8.69 ENST00000439713.2
ENST00000531131.1
ENST00000530875.1
ENST00000531709.2
ENST00000294172.2
nuclear RNA export factor 1
chr2_+_96068436 8.58 ENST00000445649.1
ENST00000447036.1
ENST00000233379.4
ENST00000418606.1
fumarylacetoacetate hydrolase domain containing 2A
chr15_-_23034322 8.55 ENST00000539711.2
ENST00000560039.1
ENST00000398013.3
ENST00000337451.3
ENST00000359727.4
ENST00000398014.2
non imprinted in Prader-Willi/Angelman syndrome 2
chr1_-_37980344 8.44 ENST00000448519.2
ENST00000373075.2
ENST00000373073.4
ENST00000296214.5
MYST/Esa1-associated factor 6
chr16_+_29827832 8.38 ENST00000609618.1
PAXIP1-associated glutamate-rich protein 1
chr16_+_70380825 8.14 ENST00000417604.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
chr8_-_37756972 7.97 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
RAB11 family interacting protein 1 (class I)
chr6_-_106773291 7.82 ENST00000343245.3
autophagy related 5
chr7_+_44646218 7.81 ENST00000444676.1
ENST00000222673.5
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr16_+_1359138 7.63 ENST00000325437.5
ubiquitin-conjugating enzyme E2I
chr11_+_67195917 7.59 ENST00000524934.1
ENST00000539188.1
ENST00000312629.5
ribosomal protein S6 kinase, 70kDa, polypeptide 2
chr11_-_64889529 7.59 ENST00000531743.1
ENST00000527548.1
ENST00000526555.1
ENST00000279259.3
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr19_+_36119929 7.47 ENST00000588161.1
ENST00000262633.4
ENST00000592202.1
ENST00000586618.1
RNA binding motif protein 42
chr11_+_64889773 7.44 ENST00000534078.1
ENST00000526171.1
ENST00000279242.2
ENST00000531705.1
ENST00000533943.1
mitochondrial ribosomal protein L49
chr6_-_106773491 7.22 ENST00000360666.4
autophagy related 5
chr6_+_20403997 7.11 ENST00000535432.1
E2F transcription factor 3
chr3_+_113775576 7.08 ENST00000485050.1
ENST00000281273.4
queuine tRNA-ribosyltransferase domain containing 1
chr6_-_106773610 7.07 ENST00000369076.3
ENST00000369070.1
autophagy related 5
chr6_+_41888926 6.99 ENST00000230340.4
bystin-like
chr16_+_29827285 6.74 ENST00000320330.6
PAXIP1 associated glutamate-rich protein 1
chr12_-_132628847 6.46 ENST00000397333.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr19_+_36120009 6.33 ENST00000589871.1
RNA binding motif protein 42
chr14_+_61447832 6.10 ENST00000354886.2
ENST00000267488.4
solute carrier family 38, member 6
chr5_-_74807418 6.10 ENST00000405807.4
ENST00000261415.7
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr1_-_186344456 6.05 ENST00000367478.4
translocated promoter region, nuclear basket protein
chr7_-_150924121 6.01 ENST00000441774.1
ENST00000222388.2
ENST00000287844.2
ATP-binding cassette, sub-family F (GCN20), member 2
chr1_+_110527308 5.84 ENST00000369799.5
adenosylhomocysteinase-like 1
chr11_-_67276100 5.61 ENST00000301488.3
cyclin-dependent kinase 2 associated protein 2
chr4_-_39460520 5.58 ENST00000503040.1
ENST00000504470.1
ENST00000508595.1
ENST00000295955.9
ribosomal protein L9
chr11_+_18344106 5.54 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
general transcription factor IIH, polypeptide 1, 62kDa
chr16_+_19078960 5.54 ENST00000568985.1
ENST00000566110.1
coenzyme Q7 homolog, ubiquinone (yeast)
chr8_+_37594130 5.53 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ER lipid raft associated 2
chr6_-_90062543 5.52 ENST00000435041.2
ubiquitin-conjugating enzyme E2, J1
chr16_+_70332956 5.39 ENST00000288071.6
ENST00000393657.2
ENST00000355992.3
ENST00000567706.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
Uncharacterized protein
chr16_+_2022036 5.35 ENST00000568546.1
transducin (beta)-like 3
chr15_-_73076030 5.30 ENST00000311669.8
ADP-dependent glucokinase
chr21_+_45079409 5.15 ENST00000340648.4
ribosomal RNA processing 1B
chr14_+_32030582 4.95 ENST00000550649.1
ENST00000281081.7
nucleotide binding protein-like
chr11_+_18343800 4.84 ENST00000453096.2
general transcription factor IIH, polypeptide 1, 62kDa
chr3_+_185304059 4.83 ENST00000427465.2
SUMO1/sentrin/SMT3 specific peptidase 2
chr3_+_11314099 4.70 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
autophagy related 7
chr14_+_31091511 4.50 ENST00000544052.2
ENST00000421551.3
ENST00000541123.1
ENST00000557076.1
ENST00000553693.1
ENST00000396629.2
sec1 family domain containing 1
chr4_-_39460496 4.47 ENST00000449470.2
ribosomal protein L9
chr11_-_10562710 4.34 ENST00000528665.1
ENST00000265981.2
ring finger protein 141
chr11_-_64889649 4.25 ENST00000434372.2
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr8_+_21946681 4.25 ENST00000289921.7
family with sequence similarity 160, member B2
chr3_+_185303962 3.85 ENST00000296257.5
SUMO1/sentrin/SMT3 specific peptidase 2
chr2_+_109335929 3.81 ENST00000283195.6
RAN binding protein 2
chr17_-_36981556 3.72 ENST00000536127.1
ENST00000225428.5
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr17_-_49198095 3.70 ENST00000505279.1
sperm associated antigen 9
chr19_+_36119975 3.68 ENST00000589559.1
ENST00000360475.4
RNA binding motif protein 42
chr12_+_120884222 3.66 ENST00000551765.1
ENST00000229384.5
glutamyl-tRNA(Gln) amidotransferase, subunit C
chr11_-_64889252 3.61 ENST00000525297.1
ENST00000529259.1
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr17_-_37009882 3.55 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
ribosomal protein L23
chr4_-_76439483 3.43 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr15_+_63481668 3.41 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B, member RAS oncogene family
chr1_+_12040238 3.40 ENST00000444836.1
ENST00000235329.5
mitofusin 2
chr19_+_58341656 3.33 ENST00000442832.4
ENST00000594901.1
zinc finger protein 587B
chr5_-_132113083 3.23 ENST00000296873.7
septin 8
chr2_+_119981384 3.20 ENST00000393108.2
ENST00000354888.5
ENST00000450943.2
ENST00000393110.2
ENST00000393106.2
ENST00000409811.1
ENST00000393107.2
STEAP family member 3, metalloreductase
chr8_-_119124045 3.12 ENST00000378204.2
exostosin glycosyltransferase 1
chr9_-_94877658 2.89 ENST00000262554.2
ENST00000337841.4
serine palmitoyltransferase, long chain base subunit 1

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
20.8 62.4 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
17.0 68.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
16.4 115.0 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
15.6 62.5 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
10.3 41.0 GO:0009386 translational attenuation(GO:0009386)
9.7 29.2 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
8.6 25.9 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
7.4 22.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
6.8 20.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
6.7 20.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
6.6 46.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
6.3 25.4 GO:0031081 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
6.1 30.6 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
5.8 23.2 GO:0009189 dTTP biosynthetic process(GO:0006235) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
5.7 17.1 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
5.7 17.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
5.2 15.7 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
4.5 67.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
3.7 25.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
3.5 13.9 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
3.4 23.6 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
3.4 13.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
3.1 18.9 GO:0048254 snoRNA localization(GO:0048254)
2.8 28.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
2.7 43.8 GO:0045116 protein neddylation(GO:0045116)
2.7 24.4 GO:2001138 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
2.5 10.1 GO:0080009 mRNA methylation(GO:0080009)
2.5 50.2 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
2.4 9.6 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
2.4 12.0 GO:0030047 actin modification(GO:0030047)
2.4 19.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
2.4 19.2 GO:0070475 rRNA base methylation(GO:0070475)
2.2 19.5 GO:0000012 single strand break repair(GO:0000012)
2.1 15.0 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
2.1 8.4 GO:0043983 histone H4-K12 acetylation(GO:0043983)
2.0 6.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
2.0 6.1 GO:0006404 RNA import into nucleus(GO:0006404)
1.9 20.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
1.8 69.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
1.8 16.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.8 8.8 GO:0061198 fungiform papilla formation(GO:0061198)
1.7 37.9 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
1.6 9.5 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
1.6 4.7 GO:0090298 late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) single-organism membrane invagination(GO:1902534)
1.5 9.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
1.4 15.9 GO:1902969 mitotic DNA replication(GO:1902969)
1.4 104.3 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
1.4 36.0 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
1.4 5.5 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.3 60.2 GO:0006378 mRNA polyadenylation(GO:0006378)
1.3 17.8 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
1.2 24.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
1.2 13.5 GO:2000210 positive regulation of anoikis(GO:2000210)
1.2 18.7 GO:0018345 protein palmitoylation(GO:0018345)
1.1 8.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
1.1 5.6 GO:2000035 regulation of stem cell division(GO:2000035)
1.1 8.7 GO:0016926 protein desumoylation(GO:0016926)
1.1 8.6 GO:0015693 magnesium ion transport(GO:0015693)
1.0 70.9 GO:0031124 mRNA 3'-end processing(GO:0031124)
1.0 16.0 GO:0000154 rRNA modification(GO:0000154)
1.0 2.0 GO:0000965 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) mitochondrial RNA 3'-end processing(GO:0000965)
0.9 48.3 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.9 2.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.9 3.6 GO:0072716 response to actinomycin D(GO:0072716) cellular response to actinomycin D(GO:0072717)
0.8 9.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.8 21.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.8 15.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.8 17.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.8 5.5 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.8 4.5 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.7 22.5 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.7 30.9 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.7 8.7 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.7 2.9 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.7 7.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.7 45.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.7 30.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.6 13.5 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.6 3.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.6 18.4 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.5 14.5 GO:0006491 N-glycan processing(GO:0006491)
0.5 30.3 GO:0043039 amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.5 15.0 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.5 5.3 GO:2000111 senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
0.5 1.9 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.5 25.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.4 25.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.4 1.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.4 32.1 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.4 10.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.3 29.6 GO:0010942 positive regulation of cell death(GO:0010942)
0.3 12.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.3 3.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 20.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.3 7.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.3 16.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.3 3.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.3 2.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 4.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 35.1 GO:0046718 viral entry into host cell(GO:0046718)
0.2 1.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 10.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 5.3 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 10.0 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 6.4 GO:0016236 macroautophagy(GO:0016236)
0.1 1.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 5.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 14.7 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 8.8 GO:0006413 translational initiation(GO:0006413)
0.0 10.7 GO:0048511 rhythmic process(GO:0048511)
0.0 1.4 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
25.5 102.1 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
15.6 62.5 GO:0005846 nuclear cap binding complex(GO:0005846)
14.6 43.8 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
13.5 67.4 GO:0032021 NELF complex(GO:0032021)
11.4 34.1 GO:0030689 Noc complex(GO:0030689)
10.0 50.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
8.4 92.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
7.4 66.4 GO:0072546 ER membrane protein complex(GO:0072546)
6.7 53.3 GO:0042382 paraspeckles(GO:0042382)
6.2 18.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
4.0 19.8 GO:0089701 U2AF(GO:0089701)
3.8 26.6 GO:0097452 GAIT complex(GO:0097452)
3.8 26.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
3.7 22.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
3.7 25.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
3.6 46.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
3.4 10.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
2.6 104.3 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
2.6 13.0 GO:0044530 supraspliceosomal complex(GO:0044530)
2.5 17.8 GO:0005663 DNA replication factor C complex(GO:0005663)
2.4 14.1 GO:0008537 proteasome activator complex(GO:0008537)
2.1 25.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
2.0 14.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
1.9 50.6 GO:0035145 exon-exon junction complex(GO:0035145)
1.8 49.8 GO:0000930 gamma-tubulin complex(GO:0000930)
1.6 30.6 GO:0036020 endolysosome membrane(GO:0036020)
1.4 37.1 GO:0071011 precatalytic spliceosome(GO:0071011)
1.4 15.1 GO:0044666 MLL3/4 complex(GO:0044666)
1.2 18.6 GO:0042405 nuclear inclusion body(GO:0042405)
1.1 17.9 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
1.1 5.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.0 30.1 GO:0005680 anaphase-promoting complex(GO:0005680)
1.0 67.3 GO:0030684 preribosome(GO:0030684)
1.0 10.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.9 88.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.8 20.3 GO:0036452 ESCRT complex(GO:0036452)
0.8 8.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.8 22.3 GO:0070822 Sin3-type complex(GO:0070822)
0.8 45.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.8 2.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.8 27.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.7 2.9 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.7 49.1 GO:0031201 SNARE complex(GO:0031201)
0.7 44.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.6 17.8 GO:0000795 synaptonemal complex(GO:0000795)
0.6 15.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.6 63.0 GO:0005643 nuclear pore(GO:0005643)
0.5 6.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.5 5.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.5 2.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.4 3.4 GO:0051286 cell tip(GO:0051286)
0.4 19.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 20.2 GO:0031519 PcG protein complex(GO:0031519)
0.3 15.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 17.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 23.0 GO:0070821 tertiary granule membrane(GO:0070821)
0.2 3.4 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.2 2.8 GO:0044754 autolysosome(GO:0044754)
0.2 1.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 8.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 12.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 24.7 GO:0005802 trans-Golgi network(GO:0005802)
0.1 9.6 GO:0036064 ciliary basal body(GO:0036064)
0.1 9.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 12.0 GO:0030175 filopodium(GO:0030175)
0.1 11.9 GO:0005681 spliceosomal complex(GO:0005681)
0.1 34.7 GO:0016607 nuclear speck(GO:0016607)
0.1 45.8 GO:0000139 Golgi membrane(GO:0000139)
0.1 4.7 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 19.4 GO:0000790 nuclear chromatin(GO:0000790)
0.1 10.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 6.8 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 6.4 GO:0019866 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.0 7.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 11.7 GO:0005635 nuclear envelope(GO:0005635)
0.0 6.6 GO:0005769 early endosome(GO:0005769)
0.0 9.2 GO:0045177 apical part of cell(GO:0045177)
0.0 1.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 41.3 GO:0070062 extracellular exosome(GO:0070062)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
9.7 29.2 GO:0004802 transketolase activity(GO:0004802)
7.8 62.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
7.2 50.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
5.7 17.1 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
5.7 102.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
5.5 43.8 GO:0019788 NEDD8 transferase activity(GO:0019788)
4.5 17.8 GO:0043398 HLH domain binding(GO:0043398)
4.0 19.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
3.9 23.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
3.8 22.8 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
3.7 25.9 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
3.7 22.1 GO:0019776 Atg8 ligase activity(GO:0019776)
3.6 68.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
3.2 13.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
3.1 15.7 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
2.8 30.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
2.8 19.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
2.7 18.9 GO:0030621 U4 snRNA binding(GO:0030621)
2.5 17.8 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
2.5 7.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
2.5 10.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
2.3 46.4 GO:0051400 BH domain binding(GO:0051400)
2.3 31.9 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
2.2 26.4 GO:0017070 U6 snRNA binding(GO:0017070)
2.2 8.7 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
2.1 19.2 GO:0008649 rRNA methyltransferase activity(GO:0008649)
2.1 14.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
2.0 14.1 GO:0061133 endopeptidase activator activity(GO:0061133)
2.0 10.0 GO:0008420 CTD phosphatase activity(GO:0008420)
1.6 16.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.6 76.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
1.5 6.1 GO:0097001 ceramide binding(GO:0097001)
1.5 48.3 GO:0008308 voltage-gated anion channel activity(GO:0008308)
1.5 40.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
1.5 26.6 GO:0035613 RNA stem-loop binding(GO:0035613)
1.4 30.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.2 18.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
1.2 9.3 GO:0000405 bubble DNA binding(GO:0000405)
1.0 24.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
1.0 5.8 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.0 2.9 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.9 37.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.9 13.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.9 3.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.9 57.7 GO:0035064 methylated histone binding(GO:0035064)
0.9 45.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.8 3.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.8 4.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.8 3.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.7 27.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.7 35.7 GO:0000049 tRNA binding(GO:0000049)
0.7 15.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.7 8.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.7 17.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.6 130.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.6 44.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.5 14.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5 33.0 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.4 24.4 GO:0005548 phospholipid transporter activity(GO:0005548)
0.4 18.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.4 18.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.4 15.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 30.4 GO:0019905 syntaxin binding(GO:0019905)
0.4 17.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.3 3.4 GO:0030911 TPR domain binding(GO:0030911)
0.3 3.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.2 5.3 GO:0030515 snoRNA binding(GO:0030515)
0.2 20.0 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.2 66.4 GO:0030246 carbohydrate binding(GO:0030246)
0.2 13.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2 0.6 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2 2.8 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.1 61.4 GO:0045296 cadherin binding(GO:0045296)
0.1 71.0 GO:0003682 chromatin binding(GO:0003682)
0.1 28.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 20.3 GO:0016247 channel regulator activity(GO:0016247)
0.1 5.5 GO:0015485 cholesterol binding(GO:0015485)
0.1 3.4 GO:0002039 p53 binding(GO:0002039)
0.1 1.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 2.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 8.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 22.1 GO:0003924 GTPase activity(GO:0003924)
0.1 1.1 GO:0031005 filamin binding(GO:0031005)
0.0 1.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 4.0 GO:0001047 core promoter binding(GO:0001047)
0.0 48.8 GO:0003723 RNA binding(GO:0003723)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 58.4 GO:0005524 ATP binding(GO:0005524)
0.0 10.3 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 14.8 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 50.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
1.4 21.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
1.0 23.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.7 19.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.6 70.8 PID E2F PATHWAY E2F transcription factor network
0.4 12.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 17.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 41.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.8 PID IL1 PATHWAY IL1-mediated signaling events
0.1 3.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 68.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
4.2 50.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
3.9 62.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.9 102.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
1.9 126.9 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
1.8 26.4 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
1.7 28.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.6 23.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
1.4 30.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
1.4 53.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
1.2 30.1 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
1.0 10.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
1.0 34.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.8 20.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.7 26.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.7 52.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.7 23.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6 14.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.6 7.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.6 18.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.5 45.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.5 2.8 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.4 22.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.4 29.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.4 12.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3 16.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.3 10.3 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.3 17.9 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.2 36.8 REACTOME TRANSLATION Genes involved in Translation
0.2 17.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 2.8 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.2 7.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.2 29.2 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.2 13.0 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.1 1.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 5.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 3.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 3.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 8.8 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 2.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions