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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for CREB3L1_CREB3

Z-value: 1.22

Motif logo

Transcription factors associated with CREB3L1_CREB3

Gene Symbol Gene ID Gene Info
ENSG00000157613.6 cAMP responsive element binding protein 3 like 1
ENSG00000107175.6 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREB3hg19_v2_chr9_+_35732312_357323320.358.8e-08Click!
CREB3L1hg19_v2_chr11_+_46316677_46316719-0.082.5e-01Click!

Activity profile of CREB3L1_CREB3 motif

Sorted Z-values of CREB3L1_CREB3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_106641728 27.31 ENST00000378026.4
cytoskeleton-associated protein 4
chr19_-_48894104 24.49 ENST00000597017.1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr7_+_128379346 23.72 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
calumenin
chr6_+_116692102 23.62 ENST00000359564.2
dermatan sulfate epimerase
chr7_+_128379449 22.74 ENST00000479257.1
calumenin
chr3_-_57583052 22.45 ENST00000496292.1
ENST00000489843.1
ADP-ribosylation factor 4
chr3_-_57583185 22.33 ENST00000463880.1
ADP-ribosylation factor 4
chr3_+_100211412 21.88 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
transmembrane protein 45A
chr2_-_69614373 20.42 ENST00000361060.5
ENST00000357308.4
glutamine--fructose-6-phosphate transaminase 1
chr3_-_57583130 20.11 ENST00000303436.6
ADP-ribosylation factor 4
chr9_+_100818976 17.48 ENST00000210444.5
N-acetylneuraminic acid synthase
chr22_+_38864041 17.47 ENST00000216014.4
ENST00000409006.3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr5_-_131562935 16.64 ENST00000379104.2
ENST00000379100.2
ENST00000428369.1
prolyl 4-hydroxylase, alpha polypeptide II
chrX_+_47441712 16.52 ENST00000218388.4
ENST00000377018.2
ENST00000456754.2
ENST00000377017.1
ENST00000441738.1
TIMP metallopeptidase inhibitor 1
chr11_+_32112431 15.74 ENST00000054950.3
reticulocalbin 1, EF-hand calcium binding domain
chr9_+_101984577 15.54 ENST00000223641.4
Sec61 beta subunit
chr9_+_114393634 14.07 ENST00000556107.1
ENST00000374294.3
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr8_-_71519889 14.04 ENST00000521425.1
translocation associated membrane protein 1
chr12_-_56123444 13.97 ENST00000546457.1
ENST00000549117.1
CD63 molecule
chr1_+_162531294 13.73 ENST00000367926.4
ENST00000271469.3
UDP-N-acteylglucosamine pyrophosphorylase 1
chr5_-_131563501 13.62 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
prolyl 4-hydroxylase, alpha polypeptide II
chr5_+_122110691 12.92 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
sorting nexin 2
chr18_-_47017956 12.15 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32 readthrough
ribosomal protein L17
chr8_+_64081118 11.82 ENST00000539294.1
YTH domain family, member 3
chr20_-_5100591 11.68 ENST00000379143.5
proliferating cell nuclear antigen
chr8_+_64081214 11.13 ENST00000542911.2
YTH domain family, member 3
chr5_-_57756087 10.76 ENST00000274289.3
polo-like kinase 2
chr11_-_14521379 10.75 ENST00000249923.3
ENST00000529866.1
ENST00000439561.2
ENST00000534771.1
coatomer protein complex, subunit beta 1
chr7_+_39663061 10.72 ENST00000005257.2
v-ral simian leukemia viral oncogene homolog A (ras related)
chr12_-_50616382 10.62 ENST00000552783.1
LIM domain and actin binding 1
chr19_-_4670345 10.33 ENST00000599630.1
ENST00000262947.3
chromosome 19 open reading frame 10
chr6_+_24775153 10.17 ENST00000356509.3
ENST00000230056.3
geminin, DNA replication inhibitor
chr3_-_107941230 10.16 ENST00000264538.3
intraflagellar transport 57 homolog (Chlamydomonas)
chr12_-_50616122 9.93 ENST00000552823.1
ENST00000552909.1
LIM domain and actin binding 1
chr7_-_30066233 9.90 ENST00000222803.5
FK506 binding protein 14, 22 kDa
chr7_+_94023873 9.86 ENST00000297268.6
collagen, type I, alpha 2
chr9_+_112542572 9.64 ENST00000374530.3
PALM2-AKAP2 readthrough
chr3_+_133292574 9.50 ENST00000264993.3
CDV3 homolog (mouse)
chr1_+_45205498 9.34 ENST00000372218.4
kinesin family member 2C
chr14_-_35344093 9.21 ENST00000382422.2
bromodomain adjacent to zinc finger domain, 1A
chr12_-_56709674 9.17 ENST00000551286.1
ENST00000549318.1
canopy FGF signaling regulator 2
Uncharacterized protein
chr19_+_50180317 9.16 ENST00000534465.1
protein arginine methyltransferase 1
chr10_-_98346801 9.14 ENST00000371142.4
transmembrane 9 superfamily member 3
chr11_+_69455855 9.04 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr12_-_120638902 9.00 ENST00000551150.1
ENST00000313104.5
ENST00000547191.1
ENST00000546989.1
ENST00000392514.4
ENST00000228306.4
ENST00000550856.1
ribosomal protein, large, P0
chr1_+_45205478 8.84 ENST00000452259.1
ENST00000372224.4
kinesin family member 2C
chr19_+_16187816 8.80 ENST00000588410.1
tropomyosin 4
chr7_-_93633658 8.73 ENST00000433727.1
Bet1 golgi vesicular membrane trafficking protein
chr19_+_5681153 8.60 ENST00000579559.1
ENST00000577222.1
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr7_-_93633684 8.55 ENST00000222547.3
ENST00000425626.1
Bet1 golgi vesicular membrane trafficking protein
chr5_+_65440032 8.49 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr5_-_10761206 8.49 ENST00000432074.2
ENST00000230895.6
death-associated protein
chr2_+_183580954 8.21 ENST00000264065.7
DnaJ (Hsp40) homolog, subfamily C, member 10
chr2_+_27255806 8.21 ENST00000238788.9
ENST00000404032.3
transmembrane protein 214
chr11_-_62341445 8.08 ENST00000329251.4
eukaryotic translation elongation factor 1 gamma
chr2_-_33824336 7.94 ENST00000431950.1
ENST00000403368.1
ENST00000441530.2
family with sequence similarity 98, member A
chrX_+_153060090 7.72 ENST00000370086.3
ENST00000370085.3
signal sequence receptor, delta
chr8_+_64081156 7.62 ENST00000517371.1
YTH domain family, member 3
chr4_-_122744998 7.47 ENST00000274026.5
cyclin A2
chr10_+_121410882 7.41 ENST00000369085.3
BCL2-associated athanogene 3
chr5_-_39425222 7.16 ENST00000320816.6
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr2_-_33824382 6.97 ENST00000238823.8
family with sequence similarity 98, member A
chr10_-_120840309 6.95 ENST00000369144.3
eukaryotic translation initiation factor 3, subunit A
chr6_-_7313381 6.94 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
signal sequence receptor, alpha
chr5_-_39425290 6.87 ENST00000545653.1
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr12_-_49318715 6.80 ENST00000444214.2
FK506 binding protein 11, 19 kDa
chr1_+_228270361 6.80 ENST00000272102.5
ENST00000540651.1
ADP-ribosylation factor 1
chr13_-_31040060 6.69 ENST00000326004.4
ENST00000341423.5
high mobility group box 1
chr7_+_16793160 6.67 ENST00000262067.4
tetraspanin 13
chr19_+_50180409 6.64 ENST00000391851.4
protein arginine methyltransferase 1
chr3_-_150264272 6.57 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
stress-associated endoplasmic reticulum protein 1
chr17_-_15466742 6.42 ENST00000584811.1
ENST00000419890.2
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
chr2_+_171785824 6.40 ENST00000452526.2
golgi reassembly stacking protein 2, 55kDa
chr1_+_228270784 6.29 ENST00000541182.1
ADP-ribosylation factor 1
chr3_-_49395705 6.23 ENST00000419349.1
glutathione peroxidase 1
chr3_+_122785895 6.12 ENST00000316218.7
protein disulfide isomerase family A, member 5
chr3_-_49395892 6.07 ENST00000419783.1
glutathione peroxidase 1
chrX_+_153059608 6.05 ENST00000370087.1
signal sequence receptor, delta
chr3_-_113465065 5.98 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr3_-_139108475 5.96 ENST00000515006.1
ENST00000513274.1
ENST00000514508.1
ENST00000507777.1
ENST00000512153.1
ENST00000333188.5
coatomer protein complex, subunit beta 2 (beta prime)
chr5_-_39425068 5.88 ENST00000515700.1
ENST00000339788.6
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr4_-_119757239 5.86 ENST00000280551.6
SEC24 family member D
chr5_+_149340282 5.86 ENST00000286298.4
solute carrier family 26 (anion exchanger), member 2
chr5_-_94890648 5.81 ENST00000513823.1
ENST00000514952.1
ENST00000358746.2
tetratricopeptide repeat domain 37
chr6_+_31916733 5.81 ENST00000483004.1
complement factor B
chr4_-_47465666 5.79 ENST00000381571.4
COMM domain containing 8
chrX_-_102941596 5.76 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
mortality factor 4 like 2
chrX_-_10544942 5.69 ENST00000380779.1
midline 1 (Opitz/BBB syndrome)
chr11_+_118443098 5.57 ENST00000392859.3
ENST00000359415.4
ENST00000534182.2
ENST00000264028.4
archain 1
chr5_-_114961858 5.56 ENST00000282382.4
ENST00000456936.3
ENST00000408996.4
TMED7-TICAM2 readthrough
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
chr17_+_57642886 5.40 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr21_+_45138941 5.32 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
pyridoxal (pyridoxine, vitamin B6) kinase
chr17_+_66511540 5.28 ENST00000588188.2
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr17_-_15466850 5.20 ENST00000438826.3
ENST00000225576.3
ENST00000519970.1
ENST00000518321.1
ENST00000428082.2
ENST00000522212.2
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
TVP23C-CDRT4 readthrough
chr1_+_151372010 5.03 ENST00000290541.6
proteasome (prosome, macropain) subunit, beta type, 4
chr21_-_38445011 4.88 ENST00000464265.1
ENST00000399102.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr8_+_109455845 4.86 ENST00000220853.3
ER membrane protein complex subunit 2
chr19_+_50180507 4.84 ENST00000454376.2
ENST00000524771.1
protein arginine methyltransferase 1
chr6_-_101329191 4.82 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
activating signal cointegrator 1 complex subunit 3
chr8_-_29208183 4.82 ENST00000240100.2
dual specificity phosphatase 4
chr4_-_83350580 4.76 ENST00000349655.4
ENST00000602300.1
heterogeneous nuclear ribonucleoprotein D-like
chr11_+_65686802 4.74 ENST00000376991.2
DR1-associated protein 1 (negative cofactor 2 alpha)
chr14_-_50087312 4.73 ENST00000298289.6
ribosomal protein L36a-like
chr1_+_42921761 4.72 ENST00000372562.1
phosphopantothenoylcysteine synthetase
chr10_-_71930222 4.61 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1 homolog A (S. cerevisiae)
chr1_-_153940097 4.56 ENST00000413622.1
ENST00000310483.6
solute carrier family 39 (zinc transporter), member 1
chr8_+_133787586 4.54 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHD finger protein 20-like 1
chr6_-_109702885 4.40 ENST00000504373.1
CD164 molecule, sialomucin
chr8_-_57906362 4.36 ENST00000262644.4
inositol monophosphatase domain containing 1
chr10_-_97416400 4.33 ENST00000371224.2
ENST00000371221.3
aldehyde dehydrogenase 18 family, member A1
chr6_-_74231444 4.32 ENST00000331523.2
ENST00000356303.2
eukaryotic translation elongation factor 1 alpha 1
chr19_-_42759300 4.29 ENST00000222329.4
Ets2 repressor factor
chr3_-_118959716 4.23 ENST00000467604.1
ENST00000491906.1
ENST00000475803.1
ENST00000479150.1
ENST00000470111.1
ENST00000459820.1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr5_-_54603368 4.19 ENST00000508346.1
ENST00000251636.5
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr7_+_100271355 4.17 ENST00000436220.1
ENST00000424361.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr2_-_130886795 4.14 ENST00000409914.2
POTE ankyrin domain family, member F
chr11_+_65686728 4.12 ENST00000312515.2
ENST00000525501.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr3_+_37903432 4.12 ENST00000443503.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr21_-_34960930 4.09 ENST00000437395.1
downstream neighbor of SON
chr16_+_81040794 4.06 ENST00000439957.3
ENST00000393335.3
ENST00000428963.2
ENST00000564669.1
centromere protein N
chr18_-_47018869 4.05 ENST00000583036.1
ENST00000580261.1
ribosomal protein L17
chr4_+_75311019 4.00 ENST00000502307.1
amphiregulin
chr21_-_38445297 3.88 ENST00000430792.1
ENST00000399103.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_+_100271446 3.87 ENST00000419828.1
ENST00000427895.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_-_43833628 3.86 ENST00000413844.2
ENST00000372458.3
ELOVL fatty acid elongase 1
chr2_-_120980939 3.82 ENST00000426077.2
transmembrane protein 185B
chr1_-_119682812 3.79 ENST00000537870.1
tryptophanyl tRNA synthetase 2, mitochondrial
chr15_-_72668805 3.78 ENST00000268097.5
hexosaminidase A (alpha polypeptide)
chr18_-_47018897 3.78 ENST00000418495.1
ribosomal protein L17
chr12_-_76953573 3.74 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
oxysterol binding protein-like 8
chr11_-_3818932 3.73 ENST00000324932.7
ENST00000359171.4
nucleoporin 98kDa
chr3_-_121468513 3.73 ENST00000494517.1
ENST00000393667.3
golgin B1
chr14_-_50053081 3.71 ENST00000396020.3
ENST00000245458.6
ribosomal protein S29
chr16_+_56642489 3.67 ENST00000561491.1
metallothionein 2A
chr11_-_67276100 3.65 ENST00000301488.3
cyclin-dependent kinase 2 associated protein 2
chr7_-_73184588 3.65 ENST00000395145.2
claudin 3
chr5_+_54603566 3.64 ENST00000230640.5
superkiller viralicidic activity 2-like 2 (S. cerevisiae)
chr5_+_54603807 3.61 ENST00000545714.1
superkiller viralicidic activity 2-like 2 (S. cerevisiae)
chr11_+_125495862 3.60 ENST00000428830.2
ENST00000544373.1
ENST00000527013.1
ENST00000526937.1
ENST00000534685.1
checkpoint kinase 1
chr6_+_63921351 3.58 ENST00000370659.1
FK506 binding protein 1C
chr18_-_47018769 3.58 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
ribosomal protein L17
chr1_+_32645269 3.51 ENST00000373610.3
taxilin alpha
chr6_-_79944336 3.48 ENST00000344726.5
ENST00000275036.7
high mobility group nucleosomal binding domain 3
chr16_-_47007545 3.46 ENST00000317089.5
DnaJ (Hsp40) homolog, subfamily A, member 2
chr20_+_23331373 3.46 ENST00000254998.2
NTF2-like export factor 1
chr16_+_56642041 3.46 ENST00000245185.5
metallothionein 2A
chr11_+_125496124 3.41 ENST00000533778.2
ENST00000534070.1
checkpoint kinase 1
chr3_-_118959733 3.40 ENST00000459778.1
ENST00000359213.3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr6_+_151561085 3.39 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr12_-_10766184 3.37 ENST00000539554.1
ENST00000381881.2
ENST00000320756.2
mago-nashi homolog B (Drosophila)
chr12_-_101801505 3.35 ENST00000539055.1
ENST00000551688.1
ENST00000551671.1
ENST00000261636.8
ADP-ribosylation factor-like 1
chr11_-_118927816 3.30 ENST00000534233.1
ENST00000532752.1
ENST00000525859.1
ENST00000404233.3
ENST00000532421.1
ENST00000543287.1
ENST00000527310.2
ENST00000529972.1
hypoxia up-regulated 1
chr6_-_74231303 3.29 ENST00000309268.6
eukaryotic translation elongation factor 1 alpha 1
chr4_-_54930790 3.28 ENST00000263921.3
cysteine-rich hydrophobic domain 2
chr14_-_78227476 3.20 ENST00000554775.1
ENST00000555761.1
ENST00000554324.1
ENST00000261531.7
SNW domain containing 1
chr11_-_118972575 3.20 ENST00000432443.2
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr16_+_53164833 3.16 ENST00000564845.1
chromodomain helicase DNA binding protein 9
chr9_+_117350009 3.05 ENST00000374050.3
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr14_+_55518349 3.02 ENST00000395468.4
mitogen-activated protein kinase 1 interacting protein 1-like
chr4_+_75310851 3.02 ENST00000395748.3
ENST00000264487.2
amphiregulin
chr1_-_38156153 3.01 ENST00000464085.1
ENST00000486637.1
ENST00000358011.4
ENST00000461359.1
chromosome 1 open reading frame 109
chr17_+_7155343 2.99 ENST00000573513.1
ENST00000354429.2
ENST00000574255.1
ENST00000396627.2
ENST00000356683.2
elongator acetyltransferase complex subunit 5
chr19_+_797443 2.94 ENST00000394601.4
ENST00000589575.1
polypyrimidine tract binding protein 1
chr19_+_54619125 2.91 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
pre-mRNA processing factor 31
chr12_+_56552128 2.87 ENST00000548580.1
ENST00000293422.5
ENST00000348108.4
ENST00000549017.1
ENST00000549566.1
ENST00000536128.1
ENST00000547649.1
ENST00000547408.1
ENST00000551589.1
ENST00000549392.1
ENST00000548400.1
ENST00000548293.1
myosin, light chain 6, alkali, smooth muscle and non-muscle
chr21_-_38445443 2.85 ENST00000360525.4
phosphatidylinositol glycan anchor biosynthesis, class P
chr3_+_169684553 2.84 ENST00000337002.4
ENST00000480708.1
SEC62 homolog (S. cerevisiae)
chr2_-_198299726 2.82 ENST00000409915.4
ENST00000487698.1
ENST00000414963.2
ENST00000335508.6
splicing factor 3b, subunit 1, 155kDa
chr2_+_28615669 2.76 ENST00000379619.1
ENST00000264716.4
FOS-like antigen 2
chr8_+_22422749 2.76 ENST00000523900.1
sorbin and SH3 domain containing 3
chr5_-_32174369 2.75 ENST00000265070.6
golgi phosphoprotein 3 (coat-protein)
chr7_+_100860949 2.75 ENST00000305105.2
zinc finger, HIT-type containing 1
chr1_-_65432171 2.74 ENST00000342505.4
Janus kinase 1
chr1_-_42801540 2.70 ENST00000372573.1
forkhead box J3
chr9_-_74980113 2.67 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
zinc finger, AN1-type domain 5
chr4_+_110736659 2.64 ENST00000394631.3
ENST00000226796.6
GAR1 ribonucleoprotein
chr10_-_111683183 2.56 ENST00000403138.2
ENST00000369683.1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr3_-_134204815 2.56 ENST00000514612.1
ENST00000510994.1
ENST00000354910.5
anaphase promoting complex subunit 13
chr8_+_140943416 2.50 ENST00000507535.3
chromosome 8 open reading frame 17
chr7_+_150929550 2.46 ENST00000482173.1
ENST00000495645.1
ENST00000035307.2
chondroitin polymerizing factor 2
chr12_+_70636765 2.43 ENST00000552231.1
ENST00000229195.3
ENST00000547780.1
ENST00000418359.3
CCR4-NOT transcription complex, subunit 2
chr3_-_121468602 2.42 ENST00000340645.5
golgin B1
chr20_+_55926583 2.38 ENST00000395840.2
ribonucleic acid export 1
chr3_-_25824872 2.34 ENST00000308710.5
N-glycanase 1
chr7_+_23145366 2.31 ENST00000339077.5
ENST00000322275.5
ENST00000539124.1
ENST00000542558.1
kelch-like family member 7
chr1_-_160313025 2.29 ENST00000368069.3
ENST00000241704.7
coatomer protein complex, subunit alpha
chr10_+_89622870 2.28 ENST00000371953.3
phosphatase and tensin homolog
chr10_-_111683308 2.25 ENST00000502935.1
ENST00000322238.8
ENST00000369680.4
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chrX_+_101854426 2.25 ENST00000536530.1
ENST00000473968.1
ENST00000604957.1
ENST00000477663.1
ENST00000479502.1
armadillo repeat containing, X-linked 5
chr1_-_119683251 2.23 ENST00000369426.5
ENST00000235521.4
tryptophanyl tRNA synthetase 2, mitochondrial
chr17_-_7218403 2.23 ENST00000570780.1
G protein pathway suppressor 2
chr14_+_31091511 2.21 ENST00000544052.2
ENST00000421551.3
ENST00000541123.1
ENST00000557076.1
ENST00000553693.1
ENST00000396629.2
sec1 family domain containing 1
chr10_+_75504105 2.06 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24 family member C
chr20_-_62738524 2.06 ENST00000369768.1
neuropeptides B/W receptor 2
chr6_+_32936353 2.04 ENST00000374825.4
bromodomain containing 2
chr16_-_73082274 2.00 ENST00000268489.5
zinc finger homeobox 3
chr11_-_3818688 2.00 ENST00000355260.3
ENST00000397004.4
ENST00000397007.4
ENST00000532475.1
nucleoporin 98kDa
chr8_+_110552337 2.00 ENST00000337573.5
estrogen receptor binding site associated, antigen, 9
chr3_-_119182523 1.99 ENST00000319172.5
transmembrane protein 39A
chr1_-_113498943 1.95 ENST00000369626.3
solute carrier family 16 (monocarboxylate transporter), member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L1_CREB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 68.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
5.0 19.9 GO:0035026 leading edge cell differentiation(GO:0035026)
4.4 13.1 GO:0036090 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
3.8 42.0 GO:0006621 protein retention in ER lumen(GO:0006621)
3.7 18.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
3.4 20.7 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
2.9 11.7 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
2.6 34.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
2.5 12.3 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
2.3 30.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
2.3 6.9 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
2.2 15.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
2.1 16.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
2.0 11.7 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
1.9 7.5 GO:0071373 cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
1.8 18.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.8 5.3 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
1.7 6.7 GO:0002840 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
1.4 7.1 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.4 5.6 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.2 6.0 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
1.2 13.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
1.2 5.9 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
1.2 7.0 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
1.1 5.7 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.1 28.6 GO:0061157 mRNA destabilization(GO:0061157)
1.1 17.5 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
1.1 14.0 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
1.0 9.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
1.0 12.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.9 23.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.9 13.0 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.9 5.6 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.9 9.0 GO:0070141 response to UV-A(GO:0070141)
0.9 10.7 GO:0051665 membrane raft localization(GO:0051665)
0.9 7.0 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.8 3.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.8 3.0 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.7 6.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.7 3.7 GO:2000035 regulation of stem cell division(GO:2000035)
0.7 4.4 GO:0006021 inositol biosynthetic process(GO:0006021)
0.7 4.3 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.7 4.8 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.7 2.8 GO:0045053 protein retention in Golgi apparatus(GO:0045053) asymmetric Golgi ribbon formation(GO:0090164)
0.7 9.9 GO:0043589 skin morphogenesis(GO:0043589)
0.6 3.9 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.6 3.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.6 3.5 GO:0046649 B cell activation(GO:0042113) lymphocyte activation(GO:0046649)
0.6 11.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.6 5.6 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.5 3.7 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.5 6.6 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.5 2.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.5 2.9 GO:0048254 snoRNA localization(GO:0048254)
0.5 9.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.5 1.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5 2.4 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.5 1.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 2.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.4 5.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.4 4.8 GO:0010815 bradykinin catabolic process(GO:0010815)
0.4 7.4 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.4 20.3 GO:0018208 peptidyl-proline modification(GO:0018208)
0.4 67.6 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.4 4.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.4 7.6 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.4 2.7 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.4 1.5 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.4 4.2 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.4 2.6 GO:0031118 snoRNA metabolic process(GO:0016074) rRNA pseudouridine synthesis(GO:0031118)
0.4 3.3 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.4 0.4 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.4 20.0 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.4 18.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.3 2.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.3 1.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.3 7.3 GO:0060972 left/right pattern formation(GO:0060972)
0.3 5.3 GO:2000480 negative regulation of meiotic nuclear division(GO:0045835) negative regulation of activated T cell proliferation(GO:0046007) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 1.7 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3 1.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 9.5 GO:0008283 cell proliferation(GO:0008283)
0.2 5.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 6.4 GO:0007030 Golgi organization(GO:0007030)
0.2 7.3 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.2 3.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 4.7 GO:0034030 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.2 0.9 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 1.7 GO:0015846 polyamine transport(GO:0015846)
0.2 2.3 GO:0002775 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.2 8.0 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.2 5.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 7.7 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.2 1.4 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.2 2.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 1.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.2 2.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 2.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 2.5 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.1 0.6 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1 4.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 8.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 2.7 GO:0043486 histone exchange(GO:0043486)
0.1 11.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 3.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 2.8 GO:0003334 keratinocyte development(GO:0003334)
0.1 8.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 2.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 58.4 GO:0043687 post-translational protein modification(GO:0043687)
0.1 3.2 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 3.5 GO:0042026 protein refolding(GO:0042026)
0.1 1.7 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.7 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 6.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.3 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.1 2.7 GO:0003016 respiratory system process(GO:0003016)
0.1 8.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 4.1 GO:0033260 nuclear DNA replication(GO:0033260)
0.1 4.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 3.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 3.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.2 GO:1903061 regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.1 2.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 3.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 4.1 GO:0001895 retina homeostasis(GO:0001895)
0.1 6.5 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 3.0 GO:0030335 positive regulation of cell migration(GO:0030335)
0.1 4.2 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.1 0.9 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.7 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.6 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 2.9 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 9.6 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 2.8 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.7 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.9 GO:0009303 rRNA transcription(GO:0009303)
0.0 4.8 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 2.3 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 1.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 1.6 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.9 GO:0006413 translational initiation(GO:0006413)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 29.3 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
4.2 46.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
3.9 54.6 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
3.9 11.7 GO:0070557 PCNA-p21 complex(GO:0070557)
2.5 7.5 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
2.2 19.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
2.2 12.9 GO:0030905 retromer, tubulation complex(GO:0030905)
2.1 14.9 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
1.5 5.8 GO:0055087 Ski complex(GO:0055087)
1.4 30.3 GO:0042599 lamellar body(GO:0042599)
1.3 13.1 GO:0030137 COPI-coated vesicle(GO:0030137)
1.2 14.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
1.2 11.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.1 20.7 GO:0034709 methylosome(GO:0034709)
1.0 5.7 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.9 9.0 GO:0097413 Lewy body(GO:0097413)
0.9 6.0 GO:0031415 NatA complex(GO:0031415)
0.8 10.2 GO:0044292 dendrite terminus(GO:0044292)
0.8 9.2 GO:0031010 ISWI-type complex(GO:0031010)
0.8 9.9 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.8 6.9 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.8 7.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.6 11.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.6 13.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.6 18.2 GO:0035371 microtubule plus-end(GO:0035371)
0.6 1.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.5 4.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.5 4.9 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.5 8.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.5 1.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.4 2.6 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.4 46.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 2.9 GO:0016461 unconventional myosin complex(GO:0016461)
0.4 31.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.4 21.3 GO:0005801 cis-Golgi network(GO:0005801)
0.4 2.7 GO:0000812 Swr1 complex(GO:0000812)
0.4 2.9 GO:0005687 U4 snRNP(GO:0005687)
0.4 47.2 GO:0032587 ruffle membrane(GO:0032587)
0.3 3.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.3 5.0 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.3 11.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.3 13.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.3 7.3 GO:0000178 exosome (RNase complex)(GO:0000178)
0.3 5.3 GO:0031588 cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588)
0.2 2.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 2.5 GO:0005686 U2 snRNP(GO:0005686)
0.2 2.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 0.6 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 1.5 GO:0042788 polysomal ribosome(GO:0042788)
0.2 2.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 9.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 5.8 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 12.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 0.9 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 15.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 46.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.8 GO:0001741 XY body(GO:0001741)
0.1 0.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 3.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 3.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 5.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.3 GO:0030904 retromer complex(GO:0030904)
0.1 10.1 GO:0005814 centriole(GO:0005814)
0.1 1.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 2.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 39.9 GO:0000139 Golgi membrane(GO:0000139)
0.1 3.3 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.1 1.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 8.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 5.3 GO:0035580 specific granule lumen(GO:0035580)
0.1 5.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 2.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 4.1 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 3.7 GO:0005874 microtubule(GO:0005874)
0.1 4.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 10.5 GO:0005681 spliceosomal complex(GO:0005681)
0.1 9.9 GO:0072562 blood microparticle(GO:0072562)
0.1 3.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 7.4 GO:0030018 Z disc(GO:0030018)
0.0 0.7 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 4.2 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 12.5 GO:0005925 focal adhesion(GO:0005925)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 2.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.3 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.9 23.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
6.1 24.5 GO:0005046 KDEL sequence binding(GO:0005046)
6.1 30.3 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
3.5 17.5 GO:0046923 ER retention sequence binding(GO:0046923)
3.4 20.7 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
3.1 80.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
2.9 11.7 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
2.6 12.9 GO:1990460 leptin receptor binding(GO:1990460)
2.4 30.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
1.8 18.2 GO:0019237 centromeric DNA binding(GO:0019237)
1.3 7.7 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
1.2 13.7 GO:0070569 uridylyltransferase activity(GO:0070569)
1.2 6.0 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
1.2 7.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
1.2 17.5 GO:0070567 cytidylyltransferase activity(GO:0070567)
1.2 11.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.1 6.7 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
1.1 4.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
1.1 3.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.0 5.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.0 2.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.9 20.4 GO:0008483 transaminase activity(GO:0008483)
0.9 19.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.9 10.8 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.9 4.4 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.8 2.5 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.8 2.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.7 2.9 GO:0030621 U4 snRNA binding(GO:0030621)
0.7 9.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.7 20.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.7 4.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.7 13.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.7 8.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.7 16.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.6 3.9 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.6 7.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.6 4.8 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.6 14.1 GO:0004871 signal transducer activity(GO:0004871)
0.5 7.1 GO:0046870 cadmium ion binding(GO:0046870)
0.5 8.8 GO:0070513 death domain binding(GO:0070513)
0.5 13.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.5 20.6 GO:0003785 actin monomer binding(GO:0003785)
0.5 1.4 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.5 6.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.4 2.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.4 1.7 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.4 12.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.3 2.7 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.3 6.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.3 2.4 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.3 4.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 16.5 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.3 1.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 5.3 GO:0030955 potassium ion binding(GO:0030955)
0.3 5.3 GO:0008603 cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 23.0 GO:0019905 syntaxin binding(GO:0019905)
0.2 50.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 3.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 3.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 4.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 4.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.2 0.6 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.2 6.4 GO:0000149 SNARE binding(GO:0000149)
0.2 10.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 4.8 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.2 4.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 1.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 5.0 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 5.8 GO:0001848 complement binding(GO:0001848)
0.2 2.1 GO:0004985 opioid receptor activity(GO:0004985)
0.2 0.9 GO:0008097 5S rRNA binding(GO:0008097)
0.2 1.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 12.9 GO:0008276 protein methyltransferase activity(GO:0008276)
0.1 10.6 GO:0019003 GDP binding(GO:0019003)
0.1 3.1 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.1 3.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 11.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 8.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 2.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 2.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 3.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.9 GO:0017166 vinculin binding(GO:0017166)
0.1 6.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 8.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 4.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 3.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 3.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 42.3 GO:0005509 calcium ion binding(GO:0005509)
0.1 0.3 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 2.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 2.3 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 2.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 10.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 3.2 GO:0004386 helicase activity(GO:0004386)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 3.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.3 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0 2.0 GO:0003682 chromatin binding(GO:0003682)
0.0 2.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 13.2 GO:0005198 structural molecule activity(GO:0005198)
0.0 5.1 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 1.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 5.6 GO:0005525 GTP binding(GO:0005525)
0.0 1.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 2.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.0 GO:0004620 phospholipase activity(GO:0004620)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 39.9 PID ARF 3PATHWAY Arf1 pathway
0.7 16.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 7.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4 9.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.4 71.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.3 5.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.3 18.2 PID AURORA B PATHWAY Aurora B signaling
0.3 6.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 2.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 15.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.3 7.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.3 26.2 PID AP1 PATHWAY AP-1 transcription factor network
0.3 19.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 4.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 2.9 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 6.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 45.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.2 11.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 4.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 4.2 PID IL1 PATHWAY IL1-mediated signaling events
0.1 5.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 4.5 PID FOXO PATHWAY FoxO family signaling
0.1 25.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 4.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 ST ADRENERGIC Adrenergic Pathway
0.0 0.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 37.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
1.5 9.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
1.1 12.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
1.1 19.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
1.0 11.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.8 58.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.7 18.2 REACTOME KINESINS Genes involved in Kinesins
0.6 11.7 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.6 12.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.5 11.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.5 76.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.5 91.0 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.5 5.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.4 25.8 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.4 7.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4 6.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 10.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.4 7.0 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.4 6.7 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.3 8.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.3 4.7 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 6.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 7.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.3 8.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 5.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.3 4.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.3 7.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 6.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.3 14.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 2.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 8.1 REACTOME TRANSLATION Genes involved in Translation
0.2 13.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 3.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 2.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 5.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 4.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 3.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 3.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 3.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 5.0 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 0.9 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 1.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 6.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 8.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 3.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.9 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 2.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases