GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
CXXC1 Links Ensembl NCBI GeneCards UniProt	ENSG00000154832.10	CXXC finger protein 1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CXXC1	hg19_v2_chr18_-_47813940_47814021	0.18	7.2e-03	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_-_80942139 Show fit	55.82	ENST00000521434.1 ENST00000519120.1 ENST00000520946.1	MRPS28 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S28
chr8_-_80942467 Show fit	54.52	ENST00000518271.1 ENST00000276585.4 ENST00000521605.1	MRPS28 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S28
chr7_+_26241325 Show fit	54.39	ENST00000456948.1 ENST00000409747.1	CBX3 Links Ensembl NCBI GeneCards UniProt Show fit	chromobox homolog 3
chrX_+_23685653 Show fit	52.34	ENST00000379331.3	PRDX4 Links Ensembl NCBI GeneCards UniProt Show fit	peroxiredoxin 4
chr4_-_174255536 Show fit	49.84	ENST00000446922.2	HMGB2 Links Ensembl NCBI GeneCards UniProt Show fit	high mobility group box 2
chr11_+_32605350 Show fit	49.83	ENST00000531120.1 ENST00000524896.1 ENST00000323213.5	EIF3M Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3, subunit M
chr5_+_95998746 Show fit	49.49	ENST00000508608.1	CAST Links Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr1_+_40723779 Show fit	48.96	ENST00000372759.3	ZMPSTE24 Links Ensembl NCBI GeneCards UniProt Show fit	zinc metallopeptidase STE24
chr3_-_185641681 Show fit	48.39	ENST00000259043.7	TRA2B Links Ensembl NCBI GeneCards UniProt Show fit	transformer 2 beta homolog (Drosophila)
chr17_-_8113886 Show fit	47.94	ENST00000577833.1 ENST00000534871.1 ENST00000583915.1 ENST00000316199.6 ENST00000581511.1 ENST00000585124.1	AURKB Links Ensembl NCBI GeneCards UniProt Show fit	aurora kinase B
chr16_-_66864806 Show fit	44.98	ENST00000566336.1 ENST00000394074.2 ENST00000563185.2 ENST00000359087.4 ENST00000379463.2 ENST00000565535.1 ENST00000290810.3	NAE1 Links Ensembl NCBI GeneCards UniProt Show fit	NEDD8 activating enzyme E1 subunit 1
chr12_+_95867919 Show fit	44.79	ENST00000261220.9 ENST00000549502.1 ENST00000553151.1 ENST00000550777.1 ENST00000551840.1	METAP2 Links Ensembl NCBI GeneCards UniProt Show fit	methionyl aminopeptidase 2
chr3_+_127323739 Show fit	44.03	ENST00000491422.1	MCM2 Links Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 2
chr8_-_80942061 Show fit	43.53	ENST00000519386.1	MRPS28 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S28
chr5_+_68462944 Show fit	43.44	ENST00000506572.1	CCNB1 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin B1
chr1_+_84944926 Show fit	42.40	ENST00000370656.1 ENST00000370654.5	RPF1 Links Ensembl NCBI GeneCards UniProt Show fit	ribosome production factor 1 homolog (S. cerevisiae)
chr13_+_43597269 Show fit	42.28	ENST00000379221.2	DNAJC15 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ (Hsp40) homolog, subfamily C, member 15
chrX_+_23685563 Show fit	42.05	ENST00000379341.4	PRDX4 Links Ensembl NCBI GeneCards UniProt Show fit	peroxiredoxin 4
chr5_+_68463043 Show fit	40.37	ENST00000508407.1 ENST00000505500.1	CCNB1 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin B1
chr1_-_151162606 Show fit	40.10	ENST00000354473.4 ENST00000368892.4	VPS72 Links Ensembl NCBI GeneCards UniProt Show fit	vacuolar protein sorting 72 homolog (S. cerevisiae)
chr15_-_91537723 Show fit	38.59	ENST00000394249.3 ENST00000559811.1 ENST00000442656.2 ENST00000557905.1 ENST00000361919.3	PRC1 Links Ensembl NCBI GeneCards UniProt Show fit	protein regulator of cytokinesis 1
chr1_-_225616515 Show fit	37.91	ENST00000338179.2 ENST00000425080.1	LBR Links Ensembl NCBI GeneCards UniProt Show fit	lamin B receptor
chr20_+_3190006 Show fit	37.43	ENST00000380113.3 ENST00000455664.2 ENST00000399838.3	ITPA Links Ensembl NCBI GeneCards UniProt Show fit	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
chr1_+_165864821 Show fit	37.42	ENST00000470820.1	UCK2 Links Ensembl NCBI GeneCards UniProt Show fit	uridine-cytidine kinase 2
chr17_-_73149921 Show fit	37.30	ENST00000481647.1 ENST00000470924.1	HN1 Links Ensembl NCBI GeneCards UniProt Show fit	hematological and neurological expressed 1
chr11_-_88070920 Show fit	36.36	ENST00000524463.1 ENST00000227266.5	CTSC Links Ensembl NCBI GeneCards UniProt Show fit	cathepsin C
chr1_-_67896009 Show fit	36.25	ENST00000370990.5	SERBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SERPINE1 mRNA binding protein 1
chr19_-_44031375 Show fit	35.80	ENST00000292147.2	ETHE1 Links Ensembl NCBI GeneCards UniProt Show fit	ethylmalonic encephalopathy 1
chr3_-_146262428 Show fit	35.26	ENST00000486631.1	PLSCR1 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr12_+_104359576 Show fit	34.70	ENST00000392872.3 ENST00000436021.2	TDG Links Ensembl NCBI GeneCards UniProt Show fit	thymine-DNA glycosylase
chr10_+_51572339 Show fit	34.57	ENST00000344348.6	NCOA4 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor coactivator 4
chr8_-_71520513 Show fit	34.45	ENST00000262213.2 ENST00000536748.1 ENST00000518678.1	TRAM1 Links Ensembl NCBI GeneCards UniProt Show fit	translocation associated membrane protein 1
chr19_-_44031341 Show fit	33.92	ENST00000600651.1	ETHE1 Links Ensembl NCBI GeneCards UniProt Show fit	ethylmalonic encephalopathy 1
chr9_+_133710453 Show fit	32.91	ENST00000318560.5	ABL1 Links Ensembl NCBI GeneCards UniProt Show fit	c-abl oncogene 1, non-receptor tyrosine kinase
chr16_+_88923494 Show fit	32.71	ENST00000567895.1 ENST00000301021.3 ENST00000565504.1 ENST00000567312.1 ENST00000568583.1 ENST00000561840.1	TRAPPC2L Links Ensembl NCBI GeneCards UniProt Show fit	trafficking protein particle complex 2-like
chr10_+_51572408 Show fit	32.45	ENST00000374082.1	NCOA4 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor coactivator 4
chr1_-_67896095 Show fit	32.05	ENST00000370994.4	SERBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SERPINE1 mRNA binding protein 1
chr11_-_14665163 Show fit	31.86	ENST00000418988.2	PSMA1 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 1
chr17_+_73201754 Show fit	31.86	ENST00000583569.1 ENST00000245544.4 ENST00000579324.1 ENST00000541827.1 ENST00000579298.1 ENST00000447371.2	NUP85 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 85kDa
chr3_-_185542761 Show fit	31.70	ENST00000457616.2 ENST00000346192.3	IGF2BP2 Links Ensembl NCBI GeneCards UniProt Show fit	insulin-like growth factor 2 mRNA binding protein 2
chr10_+_76969909 Show fit	31.48	ENST00000298468.5 ENST00000543351.1	VDAC2 Links Ensembl NCBI GeneCards UniProt Show fit	voltage-dependent anion channel 2
chr1_+_165864800 Show fit	31.47	ENST00000469256.2	UCK2 Links Ensembl NCBI GeneCards UniProt Show fit	uridine-cytidine kinase 2
chr22_+_40742497 Show fit	31.43	ENST00000216194.7	ADSL Links Ensembl NCBI GeneCards UniProt Show fit	adenylosuccinate lyase
chr1_-_222885770 Show fit	31.28	ENST00000355727.2 ENST00000340020.6	AIDA Links Ensembl NCBI GeneCards UniProt Show fit	axin interactor, dorsalization associated
chr17_-_8113542 Show fit	31.27	ENST00000578549.1 ENST00000535053.1 ENST00000582368.1	AURKB Links Ensembl NCBI GeneCards UniProt Show fit	aurora kinase B
chr7_+_141438393 Show fit	31.25	ENST00000484178.1 ENST00000473783.1 ENST00000481508.1	SSBP1 Links Ensembl NCBI GeneCards UniProt Show fit	single-stranded DNA binding protein 1, mitochondrial
chr12_+_104359641 Show fit	31.23	ENST00000537100.1	TDG Links Ensembl NCBI GeneCards UniProt Show fit	thymine-DNA glycosylase
chr2_-_44223138 Show fit	31.08	ENST00000260665.7	LRPPRC Links Ensembl NCBI GeneCards UniProt Show fit	leucine-rich pentatricopeptide repeat containing
chrX_+_77359726 Show fit	30.96	ENST00000442431.1	PGK1 Links Ensembl NCBI GeneCards UniProt Show fit	phosphoglycerate kinase 1
chrX_+_48433326 Show fit	30.60	ENST00000376755.1	RBM3 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif (RNP1, RRM) protein 3
chr10_+_124913930 Show fit	30.59	ENST00000368858.5	BUB3 Links Ensembl NCBI GeneCards UniProt Show fit	BUB3 mitotic checkpoint protein
chr1_-_67896069 Show fit	30.34	ENST00000370995.2 ENST00000361219.6	SERBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SERPINE1 mRNA binding protein 1
chr6_+_13615554 Show fit	30.32	ENST00000451315.2	NOL7 Links Ensembl NCBI GeneCards UniProt Show fit	nucleolar protein 7, 27kDa
chr11_-_47664072 Show fit	30.17	ENST00000542981.1 ENST00000530428.1 ENST00000302503.3	MTCH2 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial carrier 2
chr1_+_45212074 Show fit	29.98	ENST00000372217.1	KIF2C Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 2C
chr17_-_73150599 Show fit	29.90	ENST00000392566.2 ENST00000581874.1	HN1 Links Ensembl NCBI GeneCards UniProt Show fit	hematological and neurological expressed 1
chr2_+_171785012 Show fit	29.82	ENST00000234160.4	GORASP2 Links Ensembl NCBI GeneCards UniProt Show fit	golgi reassembly stacking protein 2, 55kDa
chr18_+_3449695 Show fit	29.29	ENST00000343820.5	TGIF1 Links Ensembl NCBI GeneCards UniProt Show fit	TGFB-induced factor homeobox 1
chr1_+_113161778 Show fit	29.20	ENST00000263168.3	CAPZA1 Links Ensembl NCBI GeneCards UniProt Show fit	capping protein (actin filament) muscle Z-line, alpha 1
chr1_+_214776516 Show fit	29.12	ENST00000366955.3	CENPF Links Ensembl NCBI GeneCards UniProt Show fit	centromere protein F, 350/400kDa
chr6_+_138725343 Show fit	29.11	ENST00000607197.1 ENST00000367697.3	HEBP2 Links Ensembl NCBI GeneCards UniProt Show fit	heme binding protein 2
chr2_+_113403434 Show fit	29.03	ENST00000272542.3	SLC20A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 20 (phosphate transporter), member 1
chr1_-_153950116 Show fit	28.94	ENST00000368589.1	JTB Links Ensembl NCBI GeneCards UniProt Show fit	jumping translocation breakpoint
chr18_+_3449821 Show fit	28.44	ENST00000407501.2 ENST00000405385.3 ENST00000546979.1	TGIF1 Links Ensembl NCBI GeneCards UniProt Show fit	TGFB-induced factor homeobox 1
chr15_-_55489097 Show fit	28.31	ENST00000260443.4	RSL24D1 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal L24 domain containing 1
chr12_-_31479045 Show fit	27.84	ENST00000539409.1 ENST00000395766.1	FAM60A Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 60, member A
chr7_+_12727250 Show fit	27.83	ENST00000404894.1	ARL4A Links Ensembl NCBI GeneCards UniProt Show fit	ADP-ribosylation factor-like 4A
chr13_+_100153665 Show fit	27.77	ENST00000376387.4	TM9SF2 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane 9 superfamily member 2
chrX_+_77359671 Show fit	27.60	ENST00000373316.4	PGK1 Links Ensembl NCBI GeneCards UniProt Show fit	phosphoglycerate kinase 1
chr16_-_2301563 Show fit	27.51	ENST00000562238.1 ENST00000566379.1 ENST00000301729.4	ECI1 Links Ensembl NCBI GeneCards UniProt Show fit	enoyl-CoA delta isomerase 1
chr1_-_40042416 Show fit	27.32	ENST00000372857.3 ENST00000372856.3 ENST00000531243.2 ENST00000451091.2	PABPC4 Links Ensembl NCBI GeneCards UniProt Show fit	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr12_+_4430371 Show fit	27.25	ENST00000179259.4	C12orf5 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 12 open reading frame 5
chr19_+_12917364 Show fit	27.11	ENST00000221486.4	RNASEH2A Links Ensembl NCBI GeneCards UniProt Show fit	ribonuclease H2, subunit A
chr19_-_13044494 Show fit	26.87	ENST00000593021.1 ENST00000587981.1 ENST00000423140.2 ENST00000314606.4	FARSA Links Ensembl NCBI GeneCards UniProt Show fit	phenylalanyl-tRNA synthetase, alpha subunit
chr19_-_2050852 Show fit	26.79	ENST00000541165.1 ENST00000591601.1	MKNK2 Links Ensembl NCBI GeneCards UniProt Show fit	MAP kinase interacting serine/threonine kinase 2
chr11_-_64013663 Show fit	26.77	ENST00000392210.2	PPP1R14B Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr3_-_185542817 Show fit	26.70	ENST00000382199.2	IGF2BP2 Links Ensembl NCBI GeneCards UniProt Show fit	insulin-like growth factor 2 mRNA binding protein 2
chr1_+_28562617 Show fit	26.60	ENST00000497986.1 ENST00000335514.5 ENST00000468425.2 ENST00000465645.1	ATPIF1 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase inhibitory factor 1
chr6_+_57037089 Show fit	26.55	ENST00000370693.5	BAG2 Links Ensembl NCBI GeneCards UniProt Show fit	BCL2-associated athanogene 2
chr11_-_14541872 Show fit	26.39	ENST00000419365.2 ENST00000530457.1 ENST00000532256.1 ENST00000533068.1	PSMA1 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 1
chr5_-_86708670 Show fit	26.35	ENST00000504878.1	CCNH Links Ensembl NCBI GeneCards UniProt Show fit	cyclin H
chr7_+_116166331 Show fit	26.33	ENST00000393468.1 ENST00000393467.1	CAV1 Links Ensembl NCBI GeneCards UniProt Show fit	caveolin 1, caveolae protein, 22kDa
chr2_+_75061108 Show fit	26.32	ENST00000290573.2	HK2 Links Ensembl NCBI GeneCards UniProt Show fit	hexokinase 2
chr12_-_49075941 Show fit	26.32	ENST00000553086.1 ENST00000548304.1	KANSL2 Links Ensembl NCBI GeneCards UniProt Show fit	KAT8 regulatory NSL complex subunit 2
chr12_-_110883346 Show fit	26.28	ENST00000547365.1	ARPC3 Links Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2/3 complex, subunit 3, 21kDa
chr1_+_236558694 Show fit	26.20	ENST00000359362.5	EDARADD Links Ensembl NCBI GeneCards UniProt Show fit	EDAR-associated death domain
chr9_+_114423615 Show fit	26.19	ENST00000374293.4	GNG10 Links Ensembl NCBI GeneCards UniProt Show fit	guanine nucleotide binding protein (G protein), gamma 10
chr19_+_16178317 Show fit	26.17	ENST00000344824.6 ENST00000538887.1	TPM4 Links Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 4
chrX_-_109561294 Show fit	26.08	ENST00000372059.2 ENST00000262844.5	AMMECR1 Links Ensembl NCBI GeneCards UniProt Show fit	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr7_+_87505544 Show fit	25.92	ENST00000265728.1	DBF4 Links Ensembl NCBI GeneCards UniProt Show fit	DBF4 homolog (S. cerevisiae)
chr11_+_10772534 Show fit	25.68	ENST00000361367.2	CTR9 Links Ensembl NCBI GeneCards UniProt Show fit	CTR9, Paf1/RNA polymerase II complex component
chr15_-_64455404 Show fit	25.63	ENST00000300026.3	PPIB Links Ensembl NCBI GeneCards UniProt Show fit	peptidylprolyl isomerase B (cyclophilin B)
chr2_-_55496344 Show fit	25.51	ENST00000403721.1 ENST00000263629.4	MTIF2 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial translational initiation factor 2
chr12_+_118454500 Show fit	25.47	ENST00000537315.1 ENST00000229043.3 ENST00000484086.2 ENST00000420967.1 ENST00000454402.2 ENST00000392542.2 ENST00000535092.1	RFC5 Links Ensembl NCBI GeneCards UniProt Show fit	replication factor C (activator 1) 5, 36.5kDa
chr1_+_29063271 Show fit	25.19	ENST00000373812.3	YTHDF2 Links Ensembl NCBI GeneCards UniProt Show fit	YTH domain family, member 2
chr5_-_37371278 Show fit	25.17	ENST00000231498.3	NUP155 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 155kDa
chr3_+_127317066 Show fit	25.08	ENST00000265056.7	MCM2 Links Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 2
chr2_-_150444116 Show fit	24.88	ENST00000428879.1 ENST00000422782.2	MMADHC Links Ensembl NCBI GeneCards UniProt Show fit	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr1_+_228270784 Show fit	24.86	ENST00000541182.1	ARF1 Links Ensembl NCBI GeneCards UniProt Show fit	ADP-ribosylation factor 1
chr3_-_10362725 Show fit	24.72	ENST00000397109.3 ENST00000428626.1 ENST00000445064.1 ENST00000431352.1 ENST00000397117.1 ENST00000337354.4 ENST00000383801.2 ENST00000432213.1 ENST00000350697.3	SEC13 Links Ensembl NCBI GeneCards UniProt Show fit	SEC13 homolog (S. cerevisiae)
chr4_-_7069760 Show fit	24.70	ENST00000264954.4	GRPEL1 Links Ensembl NCBI GeneCards UniProt Show fit	GrpE-like 1, mitochondrial (E. coli)
chr1_-_244615425 Show fit	24.69	ENST00000366535.3	ADSS Links Ensembl NCBI GeneCards UniProt Show fit	adenylosuccinate synthase
chrX_+_153991025 Show fit	24.67	ENST00000369550.5	DKC1 Links Ensembl NCBI GeneCards UniProt Show fit	dyskeratosis congenita 1, dyskerin
chr2_-_152684977 Show fit	24.64	ENST00000428992.2 ENST00000295087.8	ARL5A Links Ensembl NCBI GeneCards UniProt Show fit	ADP-ribosylation factor-like 5A
chr18_+_3451646 Show fit	24.42	ENST00000345133.5 ENST00000330513.5 ENST00000549546.1	TGIF1 Links Ensembl NCBI GeneCards UniProt Show fit	TGFB-induced factor homeobox 1
chr5_+_112196919 Show fit	24.41	ENST00000505459.1 ENST00000282999.3 ENST00000515463.1	SRP19 Links Ensembl NCBI GeneCards UniProt Show fit	signal recognition particle 19kDa
chr7_+_116139744 Show fit	24.40	ENST00000343213.2	CAV2 Links Ensembl NCBI GeneCards UniProt Show fit	caveolin 2
chr7_+_23221438 Show fit	24.20	ENST00000258742.5	NUPL2 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin like 2
chr1_+_179050512 Show fit	24.00	ENST00000367627.3	TOR3A Links Ensembl NCBI GeneCards UniProt Show fit	torsin family 3, member A
chr6_-_138428613 Show fit	23.99	ENST00000421351.3	PERP Links Ensembl NCBI GeneCards UniProt Show fit	PERP, TP53 apoptosis effector
chr8_-_21999447 Show fit	23.83	ENST00000306306.3 ENST00000521744.1	REEP4 Links Ensembl NCBI GeneCards UniProt Show fit	receptor accessory protein 4
chr1_-_153949751 Show fit	23.82	ENST00000428469.1	JTB Links Ensembl NCBI GeneCards UniProt Show fit	jumping translocation breakpoint
chr1_-_211752073 Show fit	23.79	ENST00000367001.4	SLC30A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 30 (zinc transporter), member 1
chr8_-_17104356 Show fit	23.76	ENST00000361272.4 ENST00000523917.1	CNOT7 Links Ensembl NCBI GeneCards UniProt Show fit	CCR4-NOT transcription complex, subunit 7
chr8_+_145149930 Show fit	23.71	ENST00000318911.4	CYC1 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome c-1
chr1_+_11072696 Show fit	23.67	ENST00000240185.3 ENST00000476201.1	TARDBP Links Ensembl NCBI GeneCards UniProt Show fit	TAR DNA binding protein
chr12_-_57081940 Show fit	23.65	ENST00000436399.2	PTGES3 Links Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E synthase 3 (cytosolic)
chr15_+_89787180 Show fit	23.63	ENST00000300027.8 ENST00000310775.7 ENST00000567891.1 ENST00000564920.1 ENST00000565255.1 ENST00000567996.1 ENST00000451393.2 ENST00000563250.1	FANCI Links Ensembl NCBI GeneCards UniProt Show fit	Fanconi anemia, complementation group I
chr18_+_12703002 Show fit	23.56	ENST00000590217.1	PSMG2 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) assembly chaperone 2
chr3_-_146262365 Show fit	23.49	ENST00000448787.2	PLSCR1 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr5_-_96518907 Show fit	23.49	ENST00000508447.1 ENST00000283109.3	RIOK2 Links Ensembl NCBI GeneCards UniProt Show fit	RIO kinase 2
chr17_-_40075197 Show fit	23.47	ENST00000590770.1 ENST00000590151.1	ACLY Links Ensembl NCBI GeneCards UniProt Show fit	ATP citrate lyase
chr8_-_48872686 Show fit	23.47	ENST00000314191.2 ENST00000338368.3	PRKDC Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase, DNA-activated, catalytic polypeptide
chr7_-_7680601 Show fit	23.33	ENST00000396682.2	RPA3 Links Ensembl NCBI GeneCards UniProt Show fit	replication protein A3, 14kDa
chr7_-_26240357 Show fit	23.24	ENST00000354667.4 ENST00000356674.7	HNRNPA2B1 Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein A2/B1
chr8_+_38854418 Show fit	23.18	ENST00000481513.1 ENST00000487273.2	ADAM9 Links Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 9
chr5_-_86708833 Show fit	23.15	ENST00000256897.4	CCNH Links Ensembl NCBI GeneCards UniProt Show fit	cyclin H
chr3_+_23847394 Show fit	23.08	ENST00000306627.3	UBE2E1 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-conjugating enzyme E2E 1
chrX_-_107334790 Show fit	23.04	ENST00000217958.3	PSMD10 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr12_+_27863706 Show fit	23.02	ENST00000081029.3 ENST00000538315.1 ENST00000542791.1	MRPS35 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S35
chr5_+_115177178 Show fit	22.97	ENST00000316788.7	AP3S1 Links Ensembl NCBI GeneCards UniProt Show fit	adaptor-related protein complex 3, sigma 1 subunit
chr3_-_146262293 Show fit	22.94	ENST00000448205.1	PLSCR1 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr8_-_80993010 Show fit	22.85	ENST00000537855.1 ENST00000520527.1 ENST00000517427.1 ENST00000448733.2 ENST00000379097.3	TPD52 Links Ensembl NCBI GeneCards UniProt Show fit	tumor protein D52
chr2_+_65454926 Show fit	22.55	ENST00000542850.1 ENST00000377982.4	ACTR2 Links Ensembl NCBI GeneCards UniProt Show fit	ARP2 actin-related protein 2 homolog (yeast)
chr2_+_136499287 Show fit	22.55	ENST00000415164.1	UBXN4 Links Ensembl NCBI GeneCards UniProt Show fit	UBX domain protein 4
chr3_-_146262352 Show fit	22.55	ENST00000462666.1	PLSCR1 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr14_+_35591928 Show fit	22.49	ENST00000605870.1 ENST00000557404.3	KIAA0391 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA0391
chr2_+_235860616 Show fit	22.49	ENST00000392011.2	SH3BP4 Links Ensembl NCBI GeneCards UniProt Show fit	SH3-domain binding protein 4
chr2_+_187350883 Show fit	22.44	ENST00000337859.6	ZC3H15 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 15
chr1_-_63988846 Show fit	22.38	ENST00000283568.8 ENST00000371092.3 ENST00000271002.10	ITGB3BP Links Ensembl NCBI GeneCards UniProt Show fit	integrin beta 3 binding protein (beta3-endonexin)
chr11_+_70049269 Show fit	22.36	ENST00000301838.4	FADD Links Ensembl NCBI GeneCards UniProt Show fit	Fas (TNFRSF6)-associated via death domain
chr1_+_231664390 Show fit	22.34	ENST00000366639.4 ENST00000413309.2	TSNAX Links Ensembl NCBI GeneCards UniProt Show fit	translin-associated factor X
chr3_-_146262488 Show fit	22.19	ENST00000487389.1	PLSCR1 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr2_-_209119831 Show fit	22.13	ENST00000345146.2	IDH1 Links Ensembl NCBI GeneCards UniProt Show fit	isocitrate dehydrogenase 1 (NADP+), soluble
chr1_+_151372010 Show fit	22.13	ENST00000290541.6	PSMB4 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) subunit, beta type, 4
chr12_-_6451186 Show fit	22.11	ENST00000540022.1 ENST00000536194.1	TNFRSF1A Links Ensembl NCBI GeneCards UniProt Show fit	tumor necrosis factor receptor superfamily, member 1A
chr8_+_145582217 Show fit	21.91	ENST00000530047.1 ENST00000527078.1	SLC52A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 52 (riboflavin transporter), member 2
chr7_+_102937869 Show fit	21.90	ENST00000249269.4 ENST00000428154.1 ENST00000420236.2	PMPCB Links Ensembl NCBI GeneCards UniProt Show fit	peptidase (mitochondrial processing) beta
chr21_-_26979786 Show fit	21.88	ENST00000419219.1 ENST00000352957.4 ENST00000307301.7	MRPL39 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L39
chr2_+_86333301 Show fit	21.84	ENST00000254630.7	PTCD3 Links Ensembl NCBI GeneCards UniProt Show fit	pentatricopeptide repeat domain 3
chr6_-_159065741 Show fit	21.81	ENST00000367085.3 ENST00000367089.3	DYNLT1 Links Ensembl NCBI GeneCards UniProt Show fit	dynein, light chain, Tctex-type 1
chr12_+_104359614 Show fit	21.79	ENST00000266775.9 ENST00000544861.1	TDG Links Ensembl NCBI GeneCards UniProt Show fit	thymine-DNA glycosylase
chr1_+_149822620 Show fit	21.73	ENST00000369159.2	HIST2H2AA4 Links Ensembl NCBI GeneCards UniProt Show fit	histone cluster 2, H2aa4
chr7_-_105752971 Show fit	21.49	ENST00000011473.2	SYPL1 Links Ensembl NCBI GeneCards UniProt Show fit	synaptophysin-like 1
chr2_+_198365122 Show fit	21.45	ENST00000604458.1	HSPE1-MOB4 Links Ensembl NCBI GeneCards UniProt Show fit	HSPE1-MOB4 readthrough
chr14_-_102552659 Show fit	21.40	ENST00000441629.2	HSP90AA1 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr11_+_60609537 Show fit	21.39	ENST00000227520.5	CCDC86 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 86
chr11_+_65769550 Show fit	21.38	ENST00000312175.2 ENST00000445560.2 ENST00000530204.1	BANF1 Links Ensembl NCBI GeneCards UniProt Show fit	barrier to autointegration factor 1
chr5_-_77072145 Show fit	21.35	ENST00000380377.4	TBCA Links Ensembl NCBI GeneCards UniProt Show fit	tubulin folding cofactor A
chr18_+_3451584 Show fit	21.30	ENST00000551541.1	TGIF1 Links Ensembl NCBI GeneCards UniProt Show fit	TGFB-induced factor homeobox 1
chr12_+_75874460 Show fit	21.29	ENST00000266659.3	GLIPR1 Links Ensembl NCBI GeneCards UniProt Show fit	GLI pathogenesis-related 1
chr6_+_134274322 Show fit	21.28	ENST00000367871.1 ENST00000237264.4	TBPL1 Links Ensembl NCBI GeneCards UniProt Show fit	TBP-like 1
chr2_-_169769787 Show fit	21.27	ENST00000451987.1	SPC25 Links Ensembl NCBI GeneCards UniProt Show fit	SPC25, NDC80 kinetochore complex component
chr1_-_153950098 Show fit	21.20	ENST00000356648.1	JTB Links Ensembl NCBI GeneCards UniProt Show fit	jumping translocation breakpoint
chr17_+_39846114 Show fit	21.07	ENST00000586699.1	EIF1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 1
chr5_+_34915444 Show fit	21.04	ENST00000336767.5	BRIX1 Links Ensembl NCBI GeneCards UniProt Show fit	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr2_-_70520539 Show fit	20.97	ENST00000482975.2 ENST00000438261.1	SNRPG Links Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide G
chr2_-_70520832 Show fit	20.89	ENST00000454893.1 ENST00000272348.2	SNRPG Links Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide G
chr14_+_35761580 Show fit	20.87	ENST00000553809.1 ENST00000555764.1 ENST00000556506.1	PSMA6 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 6
chrX_-_114953669 Show fit	20.87	ENST00000449327.1	RP1-241P17.4 Links Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein
chr10_+_124913793 Show fit	20.81	ENST00000368865.4 ENST00000538238.1 ENST00000368859.2	BUB3 Links Ensembl NCBI GeneCards UniProt Show fit	BUB3 mitotic checkpoint protein
chr11_-_6633799 Show fit	20.73	ENST00000299424.4	TAF10 Links Ensembl NCBI GeneCards UniProt Show fit	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr19_+_36236491 Show fit	20.60	ENST00000591949.1	PSENEN Links Ensembl NCBI GeneCards UniProt Show fit	presenilin enhancer gamma secretase subunit
chr6_-_5261141 Show fit	20.57	ENST00000330636.4 ENST00000500576.2	LYRM4 Links Ensembl NCBI GeneCards UniProt Show fit	LYR motif containing 4
chr2_-_106015527 Show fit	20.54	ENST00000344213.4 ENST00000358129.4	FHL2 Links Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 2
chr17_+_49243792 Show fit	20.50	ENST00000393183.3 ENST00000393190.1	NME1-NME2 Links Ensembl NCBI GeneCards UniProt Show fit	NME1-NME2 readthrough
chr19_+_41770978 Show fit	20.48	ENST00000593587.1 ENST00000263367.3	HNRNPUL1 Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein U-like 1
chr2_-_37899323 Show fit	20.48	ENST00000295324.3 ENST00000457889.1	CDC42EP3 Links Ensembl NCBI GeneCards UniProt Show fit	CDC42 effector protein (Rho GTPase binding) 3
chr7_-_25164969 Show fit	20.48	ENST00000305786.2	CYCS Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome c, somatic
chr2_+_216176761 Show fit	20.48	ENST00000540518.1 ENST00000435675.1	ATIC Links Ensembl NCBI GeneCards UniProt Show fit	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr8_-_21999362 Show fit	20.47	ENST00000334530.5 ENST00000518664.1	REEP4 Links Ensembl NCBI GeneCards UniProt Show fit	receptor accessory protein 4
chr16_-_85722530 Show fit	20.31	ENST00000253462.3	GINS2 Links Ensembl NCBI GeneCards UniProt Show fit	GINS complex subunit 2 (Psf2 homolog)
chr1_-_40042073 Show fit	20.29	ENST00000372858.3	PABPC4 Links Ensembl NCBI GeneCards UniProt Show fit	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr13_+_53029564 Show fit	20.27	ENST00000468284.1 ENST00000378034.3 ENST00000258607.5 ENST00000378037.5	CKAP2 Links Ensembl NCBI GeneCards UniProt Show fit	cytoskeleton associated protein 2
chr7_-_6523755 Show fit	20.20	ENST00000436575.1 ENST00000258739.4	DAGLB Links Ensembl NCBI GeneCards UniProt Show fit KDELR2 Links Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol lipase, beta KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr3_+_160117418 Show fit	20.15	ENST00000465903.1 ENST00000485645.1 ENST00000360111.2 ENST00000472991.1 ENST00000467468.1 ENST00000469762.1 ENST00000489573.1 ENST00000462787.1 ENST00000490207.1 ENST00000485867.1	SMC4 Links Ensembl NCBI GeneCards UniProt Show fit	structural maintenance of chromosomes 4
chr12_-_120638902 Show fit	19.93	ENST00000551150.1 ENST00000313104.5 ENST00000547191.1 ENST00000546989.1 ENST00000392514.4 ENST00000228306.4 ENST00000550856.1	RPLP0 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein, large, P0
chr1_-_45988542 Show fit	19.85	ENST00000424390.1	PRDX1 Links Ensembl NCBI GeneCards UniProt Show fit	peroxiredoxin 1
chr9_+_112542591 Show fit	19.83	ENST00000483909.1 ENST00000314527.4 ENST00000413420.1 ENST00000302798.7 ENST00000555236.1 ENST00000510514.5	PALM2 Links Ensembl NCBI GeneCards UniProt Show fit PALM2-AKAP2 Links Ensembl NCBI GeneCards UniProt Show fit AKAP2 Links Ensembl NCBI GeneCards UniProt Show fit	paralemmin 2 PALM2-AKAP2 readthrough A kinase (PRKA) anchor protein 2
chr14_+_73563735 Show fit	19.81	ENST00000532192.1	RBM25 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 25
chr3_-_149095652 Show fit	19.81	ENST00000305366.3	TM4SF1 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane 4 L six family member 1
chr4_+_57845043 Show fit	19.79	ENST00000433463.1 ENST00000314595.5	POLR2B Links Ensembl NCBI GeneCards UniProt Show fit	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr6_-_31774714 Show fit	19.69	ENST00000375661.5	LSM2 Links Ensembl NCBI GeneCards UniProt Show fit	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_3622893 Show fit	19.52	ENST00000407445.3 ENST00000403564.1	RPS7 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S7
chr2_+_120124497 Show fit	19.50	ENST00000355857.3 ENST00000535617.1 ENST00000535757.1 ENST00000409094.1 ENST00000311521.4	DBI Links Ensembl NCBI GeneCards UniProt Show fit	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr12_-_57082060 Show fit	19.45	ENST00000448157.2 ENST00000414274.3 ENST00000262033.6 ENST00000456859.2	PTGES3 Links Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E synthase 3 (cytosolic)
chr8_-_101734170 Show fit	19.42	ENST00000522387.1 ENST00000518196.1	PABPC1 Links Ensembl NCBI GeneCards UniProt Show fit	poly(A) binding protein, cytoplasmic 1
chr11_-_64085533 Show fit	19.40	ENST00000544844.1	TRMT112 Links Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr5_-_112257914 Show fit	19.35	ENST00000513339.1 ENST00000545426.1 ENST00000504247.1	REEP5 Links Ensembl NCBI GeneCards UniProt Show fit	receptor accessory protein 5
chr4_+_57843876 Show fit	19.27	ENST00000450656.1 ENST00000381227.1	POLR2B Links Ensembl NCBI GeneCards UniProt Show fit	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
27.9	83.8	GO:0031662	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
26.4	79.2	GO:0044878	mitotic cytokinesis checkpoint(GO:0044878)
21.9	87.7	GO:1902544	oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
19.4	155.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
18.9	94.4	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
18.7	56.1	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
18.7	18.7	GO:2000254	regulation of male germ cell proliferation(GO:2000254)
17.2	51.7	GO:0001922	B-1 B cell homeostasis(GO:0001922)
17.2	68.9	GO:0006238	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
16.3	49.0	GO:0030327	prenylated protein catabolic process(GO:0030327)
16.2	48.7	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
13.6	81.8	GO:0019418	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
13.5	13.5	GO:0060623	regulation of chromosome condensation(GO:0060623)
12.1	48.4	GO:0021796	cerebral cortex regionalization(GO:0021796)
11.5	34.6	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
11.1	33.2	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
10.6	42.4	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
10.0	69.7	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
9.6	28.9	GO:0046294	formaldehyde catabolic process(GO:0046294)
9.0	27.1	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
9.0	45.0	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
8.8	35.3	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
8.6	25.7	GO:2001162	regulation of genetic imprinting(GO:2000653) regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
8.5	25.6	GO:1901873	regulation of post-translational protein modification(GO:1901873)
8.3	24.9	GO:1902822	cleavage furrow ingression(GO:0036090) regulation of late endosome to lysosome transport(GO:1902822)
8.1	24.4	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
7.9	79.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
7.7	23.2	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
7.7	15.4	GO:0046075	dTTP metabolic process(GO:0046075)
7.7	38.3	GO:0090646	mitochondrial tRNA processing(GO:0090646)
7.7	15.3	GO:0007113	endomitotic cell cycle(GO:0007113)
7.6	45.4	GO:0042780	tRNA 3'-end processing(GO:0042780)
7.6	52.9	GO:1901526	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
7.5	15.0	GO:0046292	formaldehyde metabolic process(GO:0046292)
7.4	22.1	GO:0006097	glyoxylate cycle(GO:0006097)
7.1	28.3	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
6.9	97.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
6.9	34.6	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
6.8	27.3	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
6.7	20.2	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
6.6	32.9	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
6.3	19.0	GO:0032790	ribosome disassembly(GO:0032790)
6.3	31.6	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
6.3	18.9	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
6.2	62.2	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
6.2	37.3	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
6.2	18.5	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
6.1	18.4	GO:0015680	intracellular copper ion transport(GO:0015680)
6.1	18.4	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
6.1	42.6	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
6.0	30.0	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
5.9	5.9	GO:1903093	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
5.8	23.2	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
5.7	34.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
5.7	34.0	GO:1902957	negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
5.6	22.4	GO:0072683	T cell extravasation(GO:0072683)
5.6	16.7	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
5.5	16.6	GO:0070602	negative regulation of mitotic cell cycle, embryonic(GO:0045976) regulation of centromeric sister chromatid cohesion(GO:0070602) renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) positive regulation of determination of dorsal identity(GO:2000017)
5.5	21.9	GO:0032218	riboflavin transport(GO:0032218)
5.5	16.4	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
5.4	27.0	GO:0045337	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
5.4	102.4	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
5.3	21.4	GO:0043335	protein unfolding(GO:0043335)
5.1	20.5	GO:0046452	dihydrofolate metabolic process(GO:0046452)
5.0	49.8	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
4.9	24.7	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
4.8	19.4	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
4.8	23.8	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
4.8	4.8	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
4.7	9.5	GO:0036093	male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
4.7	14.1	GO:0019477	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
4.6	23.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
4.6	27.6	GO:0006021	inositol biosynthetic process(GO:0006021)
4.6	36.8	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
4.6	18.2	GO:0045338	farnesyl diphosphate metabolic process(GO:0045338)
4.5	13.4	GO:0035350	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
4.4	17.5	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
4.4	43.5	GO:0071763	nuclear membrane organization(GO:0071763)
4.3	12.9	GO:1900195	spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
4.3	80.9	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
4.2	17.0	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
4.2	24.9	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
4.1	29.0	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
4.1	66.1	GO:1902369	negative regulation of RNA catabolic process(GO:1902369)
4.1	20.5	GO:0055014	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
4.1	12.2	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
4.0	44.2	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
4.0	16.0	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
3.9	11.8	GO:0042256	mature ribosome assembly(GO:0042256)
3.9	137.6	GO:0007094	mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
3.9	23.5	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
3.9	42.4	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
3.8	19.2	GO:0009438	methylglyoxal metabolic process(GO:0009438)
3.7	18.6	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
3.7	7.4	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
3.7	11.0	GO:0061198	fungiform papilla formation(GO:0061198)
3.6	10.9	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
3.6	10.8	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
3.5	17.6	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
3.5	14.0	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
3.5	13.9	GO:1903976	negative regulation of glial cell migration(GO:1903976)
3.5	13.9	GO:1903644	regulation of chaperone-mediated protein folding(GO:1903644)
3.5	52.1	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
3.4	20.5	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
3.4	34.1	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
3.4	40.9	GO:0018206	peptidyl-methionine modification(GO:0018206)
3.4	10.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
3.3	13.4	GO:0030242	pexophagy(GO:0030242)
3.3	49.8	GO:0033523	histone H2B ubiquitination(GO:0033523)
3.3	46.5	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
3.3	79.6	GO:0000470	maturation of LSU-rRNA(GO:0000470)
3.3	9.9	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
3.3	13.2	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
3.3	78.1	GO:0002183	cytoplasmic translational initiation(GO:0002183)
3.2	44.8	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
3.1	12.5	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
3.1	31.3	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
3.1	31.3	GO:0051096	positive regulation of helicase activity(GO:0051096)
3.1	12.4	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
3.1	220.6	GO:0070125	mitochondrial translational elongation(GO:0070125)
3.0	9.1	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
3.0	15.2	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
3.0	6.0	GO:0046060	dATP metabolic process(GO:0046060)
3.0	24.0	GO:0002934	desmosome organization(GO:0002934)
2.9	8.8	GO:0048250	mitochondrial iron ion transport(GO:0048250)
2.9	11.6	GO:0043128	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
2.9	29.0	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
2.8	11.2	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
2.8	19.6	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
2.8	16.7	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
2.7	5.5	GO:0034201	response to oleic acid(GO:0034201)
2.7	46.5	GO:0007220	Notch receptor processing(GO:0007220)
2.7	13.6	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
2.7	8.1	GO:0048627	myoblast development(GO:0048627)
2.7	10.7	GO:0046086	adenosine biosynthetic process(GO:0046086)
2.6	15.8	GO:0001731	formation of translation preinitiation complex(GO:0001731)
2.6	13.2	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
2.6	10.4	GO:0035879	plasma membrane lactate transport(GO:0035879)
2.5	20.3	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
2.5	25.3	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
2.5	20.1	GO:0010032	meiotic chromosome condensation(GO:0010032)
2.5	7.4	GO:0061010	negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
2.5	14.8	GO:0000028	ribosomal small subunit assembly(GO:0000028)
2.5	9.9	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
2.5	9.8	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
2.5	12.3	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
2.4	9.8	GO:0071492	cellular response to UV-A(GO:0071492)
2.4	12.2	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
2.4	14.6	GO:0001675	acrosome assembly(GO:0001675)
2.4	9.7	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
2.4	16.8	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
2.4	16.8	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
2.4	11.8	GO:0061083	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
2.4	7.1	GO:1902416	positive regulation of mRNA binding(GO:1902416)
2.3	7.0	GO:0000412	histone peptidyl-prolyl isomerization(GO:0000412)
2.3	32.2	GO:0042276	error-prone translesion synthesis(GO:0042276)
2.3	38.6	GO:0051231	mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
2.3	9.1	GO:0048254	snoRNA localization(GO:0048254)
2.3	6.8	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
2.3	60.8	GO:0000027	ribosomal large subunit assembly(GO:0000027)
2.2	17.7	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
2.2	19.9	GO:0033327	Leydig cell differentiation(GO:0033327)
2.2	6.6	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
2.2	8.7	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
2.1	8.6	GO:0014040	positive regulation of Schwann cell differentiation(GO:0014040)
2.1	2.1	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
2.1	17.0	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
2.1	12.7	GO:0010643	cell communication by chemical coupling(GO:0010643)
2.1	21.1	GO:0009048	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
2.1	6.3	GO:0002901	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
2.1	58.7	GO:0031639	plasminogen activation(GO:0031639)
2.1	16.7	GO:0032055	negative regulation of translation in response to stress(GO:0032055) negative regulation of translational initiation in response to stress(GO:0032057)
2.1	85.6	GO:0006409	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
2.1	12.4	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
2.0	20.5	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
2.0	24.5	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
2.0	22.3	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
2.0	41.9	GO:0008334	histone mRNA metabolic process(GO:0008334)
2.0	9.9	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
2.0	11.7	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
1.9	7.8	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
1.9	9.7	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.9	5.8	GO:0032639	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
1.9	9.6	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.9	5.7	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
1.9	18.7	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
1.8	20.2	GO:0006621	protein retention in ER lumen(GO:0006621)
1.8	9.0	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
1.7	17.3	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
1.7	36.2	GO:0050872	white fat cell differentiation(GO:0050872)
1.7	27.4	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
1.7	30.8	GO:0019221	cytokine-mediated signaling pathway(GO:0019221)
1.7	70.8	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
1.7	5.1	GO:0050917	sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
1.7	8.4	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
1.7	10.0	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
1.7	217.8	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
1.7	5.0	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.7	14.9	GO:0010608	posttranscriptional regulation of gene expression(GO:0010608)
1.6	13.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
1.6	19.5	GO:0070365	hepatocyte differentiation(GO:0070365)
1.6	8.1	GO:0060301	vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
1.6	9.6	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
1.6	6.4	GO:2000354	regulation of ovarian follicle development(GO:2000354)
1.6	301.4	GO:0043488	regulation of mRNA stability(GO:0043488)
1.6	23.5	GO:0006107	oxaloacetate metabolic process(GO:0006107)
1.5	12.3	GO:0006013	mannose metabolic process(GO:0006013)
1.5	65.9	GO:0061462	protein localization to lysosome(GO:0061462)
1.5	23.0	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
1.5	10.7	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
1.5	28.7	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
1.5	27.1	GO:0044818	mitotic G2 DNA damage checkpoint(GO:0007095) mitotic G2/M transition checkpoint(GO:0044818)
1.5	15.0	GO:0015939	pantothenate metabolic process(GO:0015939)
1.5	7.5	GO:0031648	protein destabilization(GO:0031648)
1.5	41.5	GO:0043968	histone H2A acetylation(GO:0043968)
1.5	24.7	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
1.5	1.5	GO:0019249	lactate biosynthetic process(GO:0019249)
1.4	4.3	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
1.4	19.6	GO:0006516	glycoprotein catabolic process(GO:0006516)
1.4	109.8	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
1.4	5.5	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
1.4	12.3	GO:1901838	regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
1.4	8.1	GO:0006177	GMP biosynthetic process(GO:0006177)
1.3	1.3	GO:2000977	regulation of forebrain neuron differentiation(GO:2000977)
1.3	60.3	GO:0043486	histone exchange(GO:0043486)
1.3	8.0	GO:0030421	defecation(GO:0030421)
1.3	39.8	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
1.3	11.9	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
1.3	10.5	GO:0015693	magnesium ion transport(GO:0015693)
1.3	3.9	GO:0071603	endothelial cell-cell adhesion(GO:0071603)
1.3	3.9	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.3	16.3	GO:1904355	positive regulation of telomere capping(GO:1904355)
1.2	5.0	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
1.2	13.6	GO:0018345	protein palmitoylation(GO:0018345)
1.2	17.2	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
1.2	7.3	GO:0034670	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
1.2	9.6	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
1.2	29.9	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
1.2	5.9	GO:0016036	cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
1.2	16.5	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
1.2	11.7	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
1.2	3.5	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.2	37.1	GO:0006301	postreplication repair(GO:0006301)
1.2	8.1	GO:1990592	protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
1.2	4.6	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
1.2	6.9	GO:0090170	regulation of Golgi inheritance(GO:0090170)
1.1	12.6	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
1.1	17.1	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
1.1	84.7	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.1	11.2	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
1.1	5.6	GO:0006983	ER overload response(GO:0006983)
1.1	12.2	GO:0035269	protein O-linked mannosylation(GO:0035269)
1.1	27.5	GO:0009235	cobalamin metabolic process(GO:0009235)
1.1	6.4	GO:0006540	glutamate decarboxylation to succinate(GO:0006540) gamma-aminobutyric acid catabolic process(GO:0009450)
1.1	3.2	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
1.0	17.6	GO:0006379	mRNA cleavage(GO:0006379)
1.0	2.1	GO:0097052	L-kynurenine metabolic process(GO:0097052)
1.0	6.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
1.0	8.1	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
1.0	4.0	GO:0031268	pseudopodium organization(GO:0031268)
1.0	5.0	GO:0030047	actin modification(GO:0030047)
1.0	10.8	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
1.0	2.9	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
1.0	25.0	GO:0007080	mitotic metaphase plate congression(GO:0007080)
1.0	3.8	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.9	2.8	GO:0043317	regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318) insulin catabolic process(GO:1901143)
0.9	13.2	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.9	8.3	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.9	9.1	GO:0031053	primary miRNA processing(GO:0031053)
0.9	43.3	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.9	42.9	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.9	2.7	GO:1903526	negative regulation of membrane tubulation(GO:1903526)
0.9	19.2	GO:1904667	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.9	51.9	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.9	1.7	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.8	3.4	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.8	2.5	GO:0051402	neuron apoptotic process(GO:0051402)
0.8	2.5	GO:0009303	rRNA transcription(GO:0009303)
0.8	10.8	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.8	6.6	GO:0007007	inner mitochondrial membrane organization(GO:0007007) cristae formation(GO:0042407)
0.8	17.7	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.8	4.8	GO:0032328	alanine transport(GO:0032328)
0.8	46.8	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.8	9.4	GO:0044744	protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.8	4.7	GO:0036258	multivesicular body assembly(GO:0036258)
0.8	3.1	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.8	2.3	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.8	5.3	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.7	5.2	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.7	5.9	GO:0000070	mitotic sister chromatid segregation(GO:0000070)
0.7	17.5	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.7	30.6	GO:0045727	positive regulation of translation(GO:0045727)
0.7	5.7	GO:0051601	exocyst localization(GO:0051601)
0.7	6.4	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.7	5.6	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.7	7.6	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.7	3.5	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.7	10.2	GO:0000338	protein deneddylation(GO:0000338)
0.7	4.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.7	96.9	GO:0000910	cytokinesis(GO:0000910)
0.7	126.6	GO:0000398	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.7	11.2	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.7	3.9	GO:0055064	chloride ion homeostasis(GO:0055064)
0.6	6.5	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.6	26.5	GO:1900034	regulation of cellular response to heat(GO:1900034)
0.6	30.3	GO:0032272	negative regulation of protein polymerization(GO:0032272)
0.6	2.5	GO:0032489	aminophospholipid transport(GO:0015917) regulation of Cdc42 protein signal transduction(GO:0032489) platelet dense granule organization(GO:0060155) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.6	32.5	GO:0042348	regulation of NF-kappaB import into nucleus(GO:0042345) NF-kappaB import into nucleus(GO:0042348)
0.6	25.2	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.6	4.3	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.6	3.0	GO:0001315	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.6	26.7	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.6	10.1	GO:0000732	strand displacement(GO:0000732)
0.6	6.5	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.6	1.8	GO:0071934	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.6	1.8	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.6	6.4	GO:1904886	beta-catenin destruction complex disassembly(GO:1904886)
0.6	12.7	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.6	16.7	GO:0031581	hemidesmosome assembly(GO:0031581)
0.6	10.3	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.6	5.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.6	21.7	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.6	2.8	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.6	1.7	GO:0097033	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.6	5.6	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.5	2.7	GO:0021759	globus pallidus development(GO:0021759)
0.5	8.1	GO:0016579	protein deubiquitination(GO:0016579)
0.5	7.5	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.5	26.2	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.5	6.2	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.5	3.6	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.5	29.4	GO:0006413	translational initiation(GO:0006413)
0.5	52.4	GO:0006338	chromatin remodeling(GO:0006338)
0.5	4.9	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.5	1.9	GO:0048388	endosomal lumen acidification(GO:0048388)
0.5	12.1	GO:0050873	brown fat cell differentiation(GO:0050873)
0.5	3.3	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.5	35.8	GO:0008033	tRNA processing(GO:0008033)
0.5	2.3	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.5	12.2	GO:2001222	regulation of neuron migration(GO:2001222)
0.5	15.8	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.4	5.4	GO:0048311	mitochondrion distribution(GO:0048311)
0.4	6.6	GO:0051639	actin filament network formation(GO:0051639)
0.4	12.5	GO:0006270	DNA replication initiation(GO:0006270)
0.4	2.1	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.4	5.9	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.4	3.8	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.4	4.6	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.4	3.3	GO:0016180	snRNA processing(GO:0016180)
0.4	8.5	GO:0044804	nucleophagy(GO:0044804)
0.4	16.8	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
0.4	2.6	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.4	14.0	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4	10.8	GO:0043304	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.4	8.2	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.4	2.8	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.3	2.8	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.3	3.8	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130)
0.3	3.1	GO:0045109	intermediate filament organization(GO:0045109)
0.3	8.2	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.3	2.3	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.3	1.6	GO:0046952	ketone body catabolic process(GO:0046952)
0.3	3.6	GO:0006183	GTP biosynthetic process(GO:0006183)
0.3	2.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.3	1.9	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.3	26.2	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.3	18.9	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.3	18.9	GO:0045454	cell redox homeostasis(GO:0045454)
0.3	10.8	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.3	1.2	GO:0031054	pre-miRNA processing(GO:0031054)
0.3	8.7	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.3	2.0	GO:0070828	heterochromatin organization(GO:0070828)
0.3	2.6	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.3	17.7	GO:0006401	RNA catabolic process(GO:0006401)
0.3	3.9	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.3	5.3	GO:0032757	positive regulation of interleukin-8 production(GO:0032757)
0.3	17.6	GO:0051225	spindle assembly(GO:0051225)
0.3	9.1	GO:0010761	fibroblast migration(GO:0010761)
0.3	4.7	GO:0032508	DNA duplex unwinding(GO:0032508)
0.3	3.8	GO:0030042	actin filament depolymerization(GO:0030042)
0.2	1.2	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2	17.1	GO:0006695	cholesterol biosynthetic process(GO:0006695)
0.2	3.5	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.2	3.4	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.2	4.7	GO:0035455	response to interferon-alpha(GO:0035455)
0.2	0.6	GO:0086073	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2	2.2	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.2	5.6	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.2	2.7	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.2	3.5	GO:2000696	regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.2	13.2	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.2	1.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2	8.5	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2	2.0	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.2	3.9	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.2	0.7	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.2	22.5	GO:0070585	protein localization to mitochondrion(GO:0070585)
0.2	6.5	GO:0007565	female pregnancy(GO:0007565)
0.1	26.5	GO:0006260	DNA replication(GO:0006260)
0.1	1.2	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.1	4.8	GO:0006342	chromatin silencing(GO:0006342)
0.1	1.4	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	1.9	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.1	0.7	GO:0006477	protein sulfation(GO:0006477)
0.1	0.3	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.1	8.6	GO:1904064	positive regulation of cation transmembrane transport(GO:1904064)
0.1	4.5	GO:0015909	long-chain fatty acid transport(GO:0015909)
0.1	4.7	GO:0034394	protein localization to cell surface(GO:0034394)
0.1	12.2	GO:1902749	regulation of cell cycle G2/M phase transition(GO:1902749)
0.1	2.5	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1	10.3	GO:0030183	B cell differentiation(GO:0030183)
0.1	0.4	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.1	1.4	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.1	6.3	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1	2.0	GO:0030728	ovulation(GO:0030728)
0.1	2.0	GO:0006289	nucleotide-excision repair(GO:0006289)
0.1	7.9	GO:0007030	Golgi organization(GO:0007030)
0.1	0.7	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.1	0.7	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	0.2	GO:0050720	interleukin-1 beta biosynthetic process(GO:0050720)
0.1	1.6	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	3.4	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1	6.0	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1	5.9	GO:0002576	platelet degranulation(GO:0002576)
0.1	1.0	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.5	GO:1903943	negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0	0.6	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	5.2	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0	0.1	GO:0070673	response to interleukin-18(GO:0070673)
0.0	1.0	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.0	0.7	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.8	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.2	GO:0055098	response to lipoprotein particle(GO:0055094) response to low-density lipoprotein particle(GO:0055098) cellular response to lipoprotein particle stimulus(GO:0071402) cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.0	2.7	GO:0031424	keratinization(GO:0031424)
0.0	1.1	GO:0006968	cellular defense response(GO:0006968)
0.0	0.9	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.0	1.5	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	2.9	GO:0008360	regulation of cell shape(GO:0008360)
0.0	1.5	GO:0002062	chondrocyte differentiation(GO:0002062)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
17.1	51.4	GO:0033597	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
16.8	83.8	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
12.6	37.9	GO:0031262	Ndc80 complex(GO:0031262)
12.4	49.5	GO:0070985	TFIIK complex(GO:0070985)
11.5	92.1	GO:0032133	chromosome passenger complex(GO:0032133)
10.6	42.4	GO:0044611	nuclear pore inner ring(GO:0044611)
9.4	18.9	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
9.1	36.6	GO:0001405	presequence translocase-associated import motor(GO:0001405)
8.6	77.5	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
8.4	25.2	GO:0034455	t-UTP complex(GO:0034455)
8.3	25.0	GO:0031523	Myb complex(GO:0031523)
7.7	38.3	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
7.4	200.4	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
7.3	36.7	GO:0017102	methionyl glutamyl tRNA synthetase complex(GO:0017102)
6.9	89.7	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
6.7	74.0	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
6.7	13.4	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
6.6	79.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
6.5	39.0	GO:0072589	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
6.4	25.7	GO:0005606	laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
6.1	30.4	GO:0005726	perichromatin fibrils(GO:0005726)
5.9	23.8	GO:0044094	host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
5.8	46.6	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
5.5	32.9	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
5.3	58.3	GO:0070765	gamma-secretase complex(GO:0070765)
5.2	26.2	GO:0000408	EKC/KEOPS complex(GO:0000408)
5.2	41.9	GO:0005683	U7 snRNP(GO:0005683)
5.1	20.4	GO:0031417	NatC complex(GO:0031417)
5.1	20.3	GO:0000811	GINS complex(GO:0000811)
4.9	73.7	GO:0031080	nuclear pore outer ring(GO:0031080)
4.8	58.0	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
4.7	70.5	GO:0044754	autolysosome(GO:0044754)
4.7	46.6	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
4.5	27.3	GO:0070545	PeBoW complex(GO:0070545)
4.2	50.9	GO:0030008	TRAPP complex(GO:0030008)
4.2	29.2	GO:0071203	WASH complex(GO:0071203)
4.0	27.7	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
3.9	19.5	GO:0016589	NURF complex(GO:0016589)
3.9	54.4	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
3.9	15.5	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
3.9	38.6	GO:0070938	contractile ring(GO:0070938)
3.8	73.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
3.7	56.2	GO:0045277	respiratory chain complex IV(GO:0045277)
3.7	89.6	GO:0016580	Sin3 complex(GO:0016580)
3.6	10.7	GO:0005956	protein kinase CK2 complex(GO:0005956)
3.5	146.3	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
3.3	16.6	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
3.2	32.3	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
3.2	16.1	GO:0033503	HULC complex(GO:0033503)
3.2	9.6	GO:0070195	growth hormone receptor complex(GO:0070195)
3.2	25.4	GO:0030688	preribosome, small subunit precursor(GO:0030688)
3.2	9.5	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
3.1	24.4	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
3.0	3.0	GO:0048500	signal recognition particle(GO:0048500)
2.9	20.2	GO:0005955	calcineurin complex(GO:0005955)
2.8	19.7	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
2.8	83.1	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
2.7	13.6	GO:0089701	U2AF(GO:0089701)
2.7	18.9	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
2.6	44.7	GO:0005686	U2 snRNP(GO:0005686)
2.6	186.3	GO:0005637	nuclear inner membrane(GO:0005637)
2.6	13.0	GO:0097422	tubular endosome(GO:0097422)
2.6	61.7	GO:0005697	telomerase holoenzyme complex(GO:0005697)
2.5	40.8	GO:0030014	CCR4-NOT complex(GO:0030014)
2.5	35.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
2.4	14.5	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
2.4	7.2	GO:0035189	Rb-E2F complex(GO:0035189)
2.4	16.7	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
2.4	9.6	GO:0045323	interleukin-1 receptor complex(GO:0045323)
2.4	14.1	GO:0071817	MMXD complex(GO:0071817)
2.3	37.3	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
2.3	20.7	GO:0000125	PCAF complex(GO:0000125)
2.3	9.1	GO:0005687	U4 snRNP(GO:0005687)
2.2	13.5	GO:0001740	Barr body(GO:0001740)
2.2	20.1	GO:0000796	condensin complex(GO:0000796)
2.1	17.2	GO:0034719	SMN-Sm protein complex(GO:0034719)
2.1	12.7	GO:0070470	plasma membrane respiratory chain(GO:0070470)
2.1	12.6	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
2.1	14.6	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
2.1	23.0	GO:0030123	AP-3 adaptor complex(GO:0030123)
2.0	6.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
2.0	34.6	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
2.0	14.1	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
2.0	10.0	GO:0043527	tRNA methyltransferase complex(GO:0043527)
2.0	35.5	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
2.0	31.2	GO:0032433	filopodium tip(GO:0032433)
1.9	17.5	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
1.9	43.8	GO:0030687	preribosome, large subunit precursor(GO:0030687)
1.9	26.6	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
1.8	14.7	GO:0042382	paraspeckles(GO:0042382)
1.8	3.6	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
1.8	8.9	GO:0071986	Ragulator complex(GO:0071986)
1.8	28.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
1.8	3.5	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.7	87.1	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.7	16.9	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
1.7	36.9	GO:0002080	acrosomal membrane(GO:0002080)
1.7	31.8	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
1.7	3.3	GO:0071159	NF-kappaB complex(GO:0071159)
1.6	4.9	GO:0005674	transcription factor TFIIF complex(GO:0005674)
1.6	11.3	GO:0016272	prefoldin complex(GO:0016272)
1.6	31.2	GO:0030137	COPI-coated vesicle(GO:0030137)
1.6	4.7	GO:0033565	ESCRT-0 complex(GO:0033565)
1.6	23.3	GO:0005662	DNA replication factor A complex(GO:0005662)
1.5	10.8	GO:0044194	cytolytic granule(GO:0044194)
1.5	16.7	GO:0005641	nuclear envelope lumen(GO:0005641)
1.5	28.8	GO:0030686	90S preribosome(GO:0030686)
1.5	19.2	GO:0008385	IkappaB kinase complex(GO:0008385)
1.5	11.6	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.4	8.6	GO:0097452	GAIT complex(GO:0097452)
1.4	146.9	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
1.4	5.6	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
1.4	18.3	GO:0005838	proteasome regulatory particle(GO:0005838)
1.4	25.1	GO:0097342	ripoptosome(GO:0097342)
1.4	9.7	GO:0002178	palmitoyltransferase complex(GO:0002178)
1.4	9.7	GO:0030870	Mre11 complex(GO:0030870)
1.4	5.5	GO:0042788	polysomal ribosome(GO:0042788)
1.4	26.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
1.4	8.2	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
1.4	35.5	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
1.4	12.3	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
1.3	105.0	GO:0070469	respiratory chain(GO:0070469)
1.3	18.7	GO:0097227	sperm annulus(GO:0097227)
1.3	13.3	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
1.3	17.3	GO:0002199	zona pellucida receptor complex(GO:0002199)
1.3	16.6	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
1.3	7.6	GO:0005828	kinetochore microtubule(GO:0005828)
1.3	21.5	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.3	37.9	GO:0030057	desmosome(GO:0030057)
1.3	5.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
1.2	7.5	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
1.2	83.6	GO:0005881	cytoplasmic microtubule(GO:0005881)
1.2	79.9	GO:0015935	small ribosomal subunit(GO:0015935)
1.2	21.4	GO:0071682	endocytic vesicle lumen(GO:0071682)
1.1	14.9	GO:0000815	ESCRT III complex(GO:0000815)
1.1	8.9	GO:0042575	DNA polymerase complex(GO:0042575)
1.1	10.6	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
1.1	3.2	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
1.0	7.3	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
1.0	179.4	GO:0005681	spliceosomal complex(GO:0005681)
1.0	97.9	GO:0035578	azurophil granule lumen(GO:0035578)
1.0	39.7	GO:0000502	proteasome complex(GO:0000502)
1.0	48.8	GO:0010494	cytoplasmic stress granule(GO:0010494)
1.0	10.1	GO:0042555	MCM complex(GO:0042555)
1.0	13.0	GO:0097470	ribbon synapse(GO:0097470)
1.0	12.7	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
1.0	4.9	GO:0005899	insulin receptor complex(GO:0005899)
1.0	90.7	GO:0005643	nuclear pore(GO:0005643)
0.9	6.6	GO:0000813	ESCRT I complex(GO:0000813)
0.9	6.5	GO:0045171	intercellular bridge(GO:0045171)
0.9	35.7	GO:0044391	ribosomal subunit(GO:0044391)
0.8	22.6	GO:0031970	mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.8	4.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.8	5.0	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.8	17.9	GO:0031143	pseudopodium(GO:0031143)
0.8	7.2	GO:0070652	HAUS complex(GO:0070652)
0.8	27.3	GO:0005876	spindle microtubule(GO:0005876)
0.8	19.2	GO:0005680	anaphase-promoting complex(GO:0005680)
0.8	33.1	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.8	17.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.7	85.0	GO:0016605	PML body(GO:0016605)
0.7	8.1	GO:0097443	sorting endosome(GO:0097443)
0.7	36.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.7	12.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.7	8.4	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.7	8.4	GO:0033093	Weibel-Palade body(GO:0033093)
0.7	14.2	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.6	5.6	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.6	4.8	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.6	6.8	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.5	5.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.5	30.9	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.5	5.0	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.5	24.5	GO:0001772	immunological synapse(GO:0001772)
0.5	5.1	GO:0005640	nuclear outer membrane(GO:0005640)
0.5	33.1	GO:1904724	tertiary granule lumen(GO:1904724)
0.5	41.0	GO:1902493	protein acetyltransferase complex(GO:0031248) acetyltransferase complex(GO:1902493)
0.4	6.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.4	17.3	GO:0031430	M band(GO:0031430)
0.4	4.0	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.4	7.9	GO:0042599	lamellar body(GO:0042599)
0.4	5.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.4	3.3	GO:0032039	integrator complex(GO:0032039)
0.4	20.2	GO:0005801	cis-Golgi network(GO:0005801)
0.4	6.8	GO:0005720	nuclear heterochromatin(GO:0005720)
0.4	299.8	GO:0005730	nucleolus(GO:0005730)
0.4	48.3	GO:0030496	midbody(GO:0030496)
0.3	20.6	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3	9.8	GO:1904115	axon cytoplasm(GO:1904115)
0.3	17.1	GO:0005667	transcription factor complex(GO:0005667)
0.3	5.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.3	10.2	GO:0008180	COP9 signalosome(GO:0008180)
0.3	2.0	GO:0070554	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.3	5.8	GO:0005771	multivesicular body(GO:0005771)
0.3	15.2	GO:0035577	azurophil granule membrane(GO:0035577)
0.3	1.9	GO:0005610	laminin-5 complex(GO:0005610)
0.3	2.1	GO:0005844	polysome(GO:0005844)
0.3	3.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3	6.2	GO:0035580	specific granule lumen(GO:0035580)
0.3	26.7	GO:0035579	specific granule membrane(GO:0035579)
0.2	4.5	GO:0031527	filopodium membrane(GO:0031527)
0.2	1.5	GO:0097539	ciliary transition fiber(GO:0097539)
0.2	1.9	GO:0042581	specific granule(GO:0042581)
0.2	62.4	GO:0005635	nuclear envelope(GO:0005635)
0.2	19.9	GO:0005905	clathrin-coated pit(GO:0005905)
0.2	5.9	GO:0005921	gap junction(GO:0005921)
0.2	1.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.2	48.8	GO:0005783	endoplasmic reticulum(GO:0005783)
0.2	3.8	GO:0005581	collagen trimer(GO:0005581)
0.2	4.5	GO:0031904	endosome lumen(GO:0031904)
0.1	0.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	5.4	GO:0002102	podosome(GO:0002102)
0.1	2.2	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.1	33.0	GO:0019866	organelle inner membrane(GO:0019866)
0.1	2.2	GO:0030056	hemidesmosome(GO:0030056)
0.1	4.7	GO:0005884	actin filament(GO:0005884)
0.1	10.7	GO:0005796	Golgi lumen(GO:0005796)
0.1	2.5	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1	4.0	GO:0045095	keratin filament(GO:0045095)
0.1	3.4	GO:0005811	lipid particle(GO:0005811)
0.1	12.1	GO:0032993	protein-DNA complex(GO:0032993)
0.1	2.5	GO:0016363	nuclear matrix(GO:0016363)
0.1	4.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.1	2.5	GO:0016324	apical plasma membrane(GO:0016324)
0.1	9.4	GO:0030018	Z disc(GO:0030018)
0.1	5.1	GO:0030175	filopodium(GO:0030175)
0.1	19.8	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	0.2	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0	4.3	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	3.2	GO:0031902	late endosome membrane(GO:0031902)
0.0	2.5	GO:0030017	sarcomere(GO:0030017)
0.0	3.1	GO:0005903	brush border(GO:0005903)
0.0	0.3	GO:0044309	dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0	0.4	GO:0097546	ciliary base(GO:0097546)
0.0	1.0	GO:0034707	chloride channel complex(GO:0034707)
0.0	3.0	GO:0000785	chromatin(GO:0000785)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
29.2	87.7	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
19.5	58.6	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
17.3	51.9	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
16.7	133.4	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
16.5	49.5	GO:0042134	rRNA primary transcript binding(GO:0042134)
15.9	47.6	GO:0017130	poly(C) RNA binding(GO:0017130)
12.8	140.9	GO:0017128	phospholipid scramblase activity(GO:0017128)
12.6	37.9	GO:0050613	delta14-sterol reductase activity(GO:0050613)
12.5	37.4	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
12.5	49.8	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
12.0	83.8	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
10.8	43.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
9.9	89.5	GO:0035174	histone serine kinase activity(GO:0035174)
9.8	68.9	GO:0004849	uridine kinase activity(GO:0004849)
8.9	26.6	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
8.8	26.3	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
8.2	49.5	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
7.4	22.1	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
7.3	29.0	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
7.2	28.7	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
6.9	27.5	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
6.8	27.3	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
6.5	39.0	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
6.4	32.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
6.3	81.7	GO:0008641	small protein activating enzyme activity(GO:0008641)
6.1	24.5	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
6.1	18.3	GO:0004771	sterol esterase activity(GO:0004771)
6.0	54.4	GO:1990226	histone methyltransferase binding(GO:1990226)
5.8	17.5	GO:0000035	acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
5.8	28.9	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
5.5	27.6	GO:0052832	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
5.5	21.9	GO:0032217	riboflavin transporter activity(GO:0032217)
5.5	16.4	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
5.4	76.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
5.4	27.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
5.4	27.0	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
5.3	63.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
5.0	20.2	GO:0005046	KDEL sequence binding(GO:0005046)
5.0	44.6	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
4.7	61.6	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
4.7	28.2	GO:0016531	copper chaperone activity(GO:0016531)
4.7	23.5	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
4.6	13.9	GO:0010698	acetyltransferase activator activity(GO:0010698)
4.6	18.2	GO:0051996	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
4.6	77.4	GO:0003688	DNA replication origin binding(GO:0003688)
4.5	13.4	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
4.4	8.7	GO:0003998	acylphosphatase activity(GO:0003998)
4.3	52.1	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
4.2	16.7	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
4.1	36.5	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
4.0	16.2	GO:0052827	inositol pentakisphosphate phosphatase activity(GO:0052827)
4.0	12.0	GO:0015131	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
3.9	31.4	GO:0016842	amidine-lyase activity(GO:0016842)
3.9	116.4	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
3.8	23.1	GO:0042296	ISG15 transferase activity(GO:0042296)
3.8	22.8	GO:0019238	cyclohydrolase activity(GO:0019238)
3.7	37.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
3.7	14.6	GO:0043515	kinetochore binding(GO:0043515)
3.6	18.1	GO:0047134	protein-disulfide reductase activity(GO:0047134)
3.5	14.1	GO:0016748	succinyltransferase activity(GO:0016748)
3.5	102.4	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
3.5	31.5	GO:0015288	porin activity(GO:0015288)
3.5	100.3	GO:0070410	co-SMAD binding(GO:0070410)
3.4	13.6	GO:0008184	purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
3.4	37.3	GO:0005049	nuclear export signal receptor activity(GO:0005049)
3.3	10.0	GO:0000773	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
3.3	23.1	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
3.3	9.9	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)
3.3	26.3	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
3.3	22.8	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
3.2	9.7	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
3.2	134.5	GO:0031369	translation initiation factor binding(GO:0031369)
3.2	9.6	GO:0005148	prolactin receptor binding(GO:0005148)
3.2	57.0	GO:0008266	poly(U) RNA binding(GO:0008266)
3.1	12.3	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
3.1	15.4	GO:0032552	deoxyribonucleotide binding(GO:0032552)
3.1	21.4	GO:0030911	TPR domain binding(GO:0030911)
3.0	30.0	GO:0019237	centromeric DNA binding(GO:0019237)
3.0	14.8	GO:0008494	translation activator activity(GO:0008494)
2.9	61.3	GO:0001055	RNA polymerase II activity(GO:0001055)
2.9	52.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
2.9	74.3	GO:0017056	structural constituent of nuclear pore(GO:0017056)
2.8	16.9	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
2.8	11.2	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
2.8	14.0	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
2.8	28.0	GO:0042301	phosphate ion binding(GO:0042301)
2.8	5.6	GO:0044388	small protein activating enzyme binding(GO:0044388)
2.7	13.6	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
2.7	24.4	GO:0008312	7S RNA binding(GO:0008312)
2.6	41.4	GO:0004526	ribonuclease P activity(GO:0004526)
2.5	15.3	GO:0019871	sodium channel inhibitor activity(GO:0019871)
2.5	5.1	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
2.5	22.4	GO:0035877	death effector domain binding(GO:0035877)
2.5	217.9	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
2.5	41.9	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
2.4	19.6	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
2.4	29.3	GO:0031386	protein tag(GO:0031386)
2.4	48.4	GO:0070717	poly-purine tract binding(GO:0070717)
2.4	14.5	GO:0019776	Atg8 ligase activity(GO:0019776)
2.4	7.2	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
2.3	13.9	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
2.3	27.8	GO:0017070	U6 snRNA binding(GO:0017070)
2.3	6.8	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
2.3	56.4	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
2.2	10.8	GO:0030348	syntaxin-3 binding(GO:0030348)
2.1	23.6	GO:0070182	DNA polymerase binding(GO:0070182)
2.1	30.0	GO:0016018	cyclosporin A binding(GO:0016018)
2.1	89.8	GO:0000049	tRNA binding(GO:0000049)
2.1	8.4	GO:0038025	reelin receptor activity(GO:0038025)
2.1	10.4	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
2.1	47.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
2.0	6.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
2.0	8.1	GO:0003938	IMP dehydrogenase activity(GO:0003938)
2.0	60.7	GO:0070064	proline-rich region binding(GO:0070064)
2.0	36.4	GO:0031404	chloride ion binding(GO:0031404)
2.0	9.9	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
2.0	5.9	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
2.0	51.1	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
1.9	19.5	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
1.9	31.2	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
1.9	13.6	GO:0035613	RNA stem-loop binding(GO:0035613)
1.9	52.4	GO:0000993	RNA polymerase II core binding(GO:0000993)
1.9	33.6	GO:0000339	RNA cap binding(GO:0000339)
1.8	20.3	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
1.8	11.0	GO:0097322	7SK snRNA binding(GO:0097322)
1.8	7.3	GO:0004566	beta-glucuronidase activity(GO:0004566)
1.8	9.1	GO:0030621	U4 snRNA binding(GO:0030621)
1.8	12.6	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
1.8	121.6	GO:0050681	androgen receptor binding(GO:0050681)
1.8	16.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
1.7	12.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
1.7	5.0	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
1.6	6.6	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
1.6	14.4	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
1.6	9.6	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
1.6	14.3	GO:0030620	U2 snRNA binding(GO:0030620)
1.6	23.8	GO:0019855	calcium channel inhibitor activity(GO:0019855)
1.5	46.4	GO:0070063	RNA polymerase binding(GO:0070063)
1.5	4.6	GO:0035033	histone deacetylase regulator activity(GO:0035033)
1.5	31.6	GO:0003924	GTPase activity(GO:0003924)
1.4	12.6	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
1.4	11.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
1.3	89.5	GO:0008235	metalloexopeptidase activity(GO:0008235)
1.3	5.3	GO:0004530	deoxyribonuclease I activity(GO:0004530)
1.3	17.0	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
1.3	20.5	GO:0017049	GTP-Rho binding(GO:0017049)
1.2	19.8	GO:0070034	telomerase RNA binding(GO:0070034)
1.2	9.8	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
1.2	13.4	GO:0003713	transcription coactivator activity(GO:0003713)
1.2	21.0	GO:0035497	cAMP response element binding(GO:0035497)
1.2	46.6	GO:0003743	translation initiation factor activity(GO:0003743)
1.2	31.3	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
1.2	23.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
1.1	17.9	GO:0016004	phospholipase activator activity(GO:0016004)
1.1	121.1	GO:0003697	single-stranded DNA binding(GO:0003697)
1.1	6.6	GO:0004527	exonuclease activity(GO:0004527)
1.1	12.0	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
1.1	6.5	GO:0042610	CD8 receptor binding(GO:0042610)
1.1	8.7	GO:0016778	diphosphotransferase activity(GO:0016778)
1.1	13.0	GO:0034452	dynactin binding(GO:0034452)
1.1	56.9	GO:0019843	rRNA binding(GO:0019843)
1.1	6.3	GO:0004167	dopachrome isomerase activity(GO:0004167)
1.0	12.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
1.0	6.1	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
1.0	50.7	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.0	2.9	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
1.0	10.7	GO:0008253	5'-nucleotidase activity(GO:0008253)
1.0	11.6	GO:1990459	transferrin receptor binding(GO:1990459)
1.0	3.8	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.9	4.7	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.9	7.5	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.9	8.2	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.9	19.0	GO:0005123	death receptor binding(GO:0005123)
0.9	8.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.9	15.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.9	4.5	GO:0050436	microfibril binding(GO:0050436)
0.9	43.5	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.9	34.5	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.9	30.1	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.9	9.7	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.9	3.5	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.9	2.6	GO:0015235	cobalamin transporter activity(GO:0015235)
0.9	20.8	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.8	5.9	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.8	2.5	GO:0034188	apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.8	9.0	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.8	28.5	GO:0001671	ATPase activator activity(GO:0001671)
0.8	19.6	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.8	18.7	GO:0036002	pre-mRNA binding(GO:0036002)
0.8	3.1	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.8	23.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.7	10.2	GO:0030515	snoRNA binding(GO:0030515)
0.7	12.3	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.7	12.7	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.7	86.7	GO:0047485	protein N-terminus binding(GO:0047485)
0.7	30.2	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.7	3.5	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.7	2.8	GO:0004966	galanin receptor activity(GO:0004966)
0.7	2.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.7	13.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.7	107.5	GO:0003735	structural constituent of ribosome(GO:0003735)
0.7	9.9	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.7	17.7	GO:0070840	dynein complex binding(GO:0070840)
0.7	35.3	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.6	24.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.6	9.7	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.6	2.6	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.6	25.8	GO:0050699	WW domain binding(GO:0050699)
0.6	5.1	GO:0004000	adenosine deaminase activity(GO:0004000)
0.6	2.6	GO:0017040	ceramidase activity(GO:0017040)
0.6	8.2	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.6	15.7	GO:0031489	myosin V binding(GO:0031489)
0.6	10.7	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.6	6.3	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.6	6.7	GO:0019211	phosphatase activator activity(GO:0019211)
0.6	18.8	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.6	46.9	GO:0032947	protein complex scaffold(GO:0032947)
0.6	18.6	GO:0043236	laminin binding(GO:0043236)
0.6	16.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.6	1.8	GO:0015403	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.6	8.8	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.6	4.7	GO:0005536	glucose binding(GO:0005536)
0.6	5.8	GO:0048406	nerve growth factor binding(GO:0048406)
0.6	3.5	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6	14.9	GO:0042288	MHC class I protein binding(GO:0042288)
0.6	9.7	GO:0005522	profilin binding(GO:0005522)
0.5	1.6	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.5	5.5	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.5	661.4	GO:0003723	RNA binding(GO:0003723)
0.5	5.3	GO:0051430	corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.5	6.2	GO:0001056	RNA polymerase III activity(GO:0001056)
0.5	2.1	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.5	11.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.5	3.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.5	11.2	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.5	1.9	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.5	1.9	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.5	5.0	GO:0031491	nucleosome binding(GO:0031491)
0.5	68.6	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.4	1.7	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.4	34.2	GO:0043130	ubiquitin binding(GO:0043130)
0.4	2.8	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.4	4.3	GO:0016421	CoA carboxylase activity(GO:0016421)
0.4	49.5	GO:0042393	histone binding(GO:0042393)
0.4	22.9	GO:0008307	structural constituent of muscle(GO:0008307)
0.4	1.4	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
0.4	2.1	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.3	1.0	GO:0042015	interleukin-20 binding(GO:0042015)
0.3	2.3	GO:0032183	SUMO binding(GO:0032183)
0.3	4.5	GO:0009881	photoreceptor activity(GO:0009881)
0.3	2.5	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.3	5.2	GO:0071889	14-3-3 protein binding(GO:0071889)
0.3	6.9	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.3	2.7	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.3	11.6	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.3	3.5	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.3	4.6	GO:0004697	protein kinase C activity(GO:0004697)
0.3	4.0	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.3	8.2	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.3	3.6	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.3	4.9	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3	3.8	GO:0030215	semaphorin receptor binding(GO:0030215)
0.3	7.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.3	7.7	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.2	2.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.2	3.6	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.2	0.7	GO:0070728	leucine binding(GO:0070728)
0.2	4.2	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.2	1.5	GO:0004459	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.2	3.8	GO:0005537	mannose binding(GO:0005537)
0.2	2.0	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.2	0.7	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.2	2.8	GO:0005112	Notch binding(GO:0005112)
0.2	0.6	GO:1903135	cupric ion binding(GO:1903135)
0.2	3.3	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.2	0.6	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.1	2.0	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1	5.1	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1	45.4	GO:0005525	GTP binding(GO:0005525)
0.1	2.6	GO:0019239	deaminase activity(GO:0019239)
0.1	2.8	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.1	2.5	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1	0.6	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	12.3	GO:0008237	metallopeptidase activity(GO:0008237)
0.1	3.9	GO:0033613	activating transcription factor binding(GO:0033613)
0.1	0.2	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	1.9	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	0.7	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.1	0.4	GO:0004925	prolactin receptor activity(GO:0004925)
0.1	2.3	GO:0003684	damaged DNA binding(GO:0003684)
0.1	1.8	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	2.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.6	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.8	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.2	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.0	1.6	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.5	GO:0042287	MHC protein binding(GO:0042287)
0.0	0.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	9.5	GO:0019901	protein kinase binding(GO:0019901)
0.0	2.2	GO:0005179	hormone activity(GO:0005179)
0.0	0.1	GO:0004180	carboxypeptidase activity(GO:0004180)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	224.7	PID FOXM1 PATHWAY	FOXM1 transcription factor network
2.4	277.8	PID AR PATHWAY	Coregulation of Androgen receptor activity
1.8	111.9	PID ATR PATHWAY	ATR signaling pathway
1.8	32.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.8	91.2	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
1.5	49.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
1.3	49.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
1.3	56.2	PID VEGFR1 PATHWAY	VEGFR1 specific signals
1.2	89.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
1.2	27.6	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
1.1	42.5	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
1.0	49.0	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
1.0	56.1	PID AURORA B PATHWAY	Aurora B signaling
1.0	54.3	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
1.0	17.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.9	34.4	PID PLK1 PATHWAY	PLK1 signaling events
0.8	24.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.8	32.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.8	34.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.8	52.1	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.7	29.0	PID INSULIN PATHWAY	Insulin Pathway
0.7	12.8	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.7	23.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.7	37.6	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.7	17.6	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.6	60.1	PID P73PATHWAY	p73 transcription factor network
0.6	41.9	PID CDC42 PATHWAY	CDC42 signaling events
0.6	35.8	PID E2F PATHWAY	E2F transcription factor network
0.6	15.3	PID MYC PATHWAY	C-MYC pathway
0.6	75.3	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.6	11.0	PID ALK2 PATHWAY	ALK2 signaling events
0.6	16.6	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.5	34.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.4	4.9	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.4	4.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.4	21.3	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.4	15.0	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.4	18.0	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.4	10.7	ST G ALPHA I PATHWAY	G alpha i Pathway
0.4	26.7	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.4	15.9	PID MTOR 4PATHWAY	mTOR signaling pathway
0.4	17.0	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.3	3.5	SIG CHEMOTAXIS	Genes related to chemotaxis
0.3	11.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.3	8.0	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.3	7.7	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.3	8.6	PID RAC1 PATHWAY	RAC1 signaling pathway
0.3	8.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.3	20.7	PID CMYB PATHWAY	C-MYB transcription factor network
0.3	4.8	PID TRAIL PATHWAY	TRAIL signaling pathway
0.2	3.5	PID NECTIN PATHWAY	Nectin adhesion pathway
0.2	2.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.2	9.2	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	3.5	PID IFNG PATHWAY	IFN-gamma pathway
0.2	4.7	PID IL2 1PATHWAY	IL2-mediated signaling events
0.2	6.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.2	8.8	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.2	4.8	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2	3.0	PID FOXO PATHWAY	FoxO family signaling
0.1	5.0	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.6	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.4	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.4	PID IL1 PATHWAY	IL1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.2	99.5	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
6.1	92.1	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
5.0	84.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
4.1	74.5	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
4.1	61.1	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
4.1	36.6	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
3.5	283.3	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
3.5	58.7	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
3.2	93.7	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
3.2	22.4	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
3.1	31.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
3.1	178.9	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
2.9	250.6	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
2.9	28.7	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
2.9	111.6	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
2.8	39.6	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
2.8	98.5	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
2.7	118.0	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
2.7	83.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
2.6	47.2	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
2.5	5.0	REACTOME NEGATIVE REGULATION OF FGFR SIGNALING	Genes involved in Negative regulation of FGFR signaling
2.5	49.8	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
2.4	7.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
2.3	42.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
2.3	83.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
2.3	48.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
2.3	79.6	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
2.2	15.2	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
2.0	24.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
2.0	31.6	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
1.9	44.8	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
1.9	116.9	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
1.9	16.9	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.9	54.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
1.8	134.0	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.7	171.8	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
1.7	44.7	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
1.5	26.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
1.5	23.8	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
1.5	50.4	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
1.4	227.6	REACTOME TRANSLATION	Genes involved in Translation
1.4	37.6	REACTOME KINESINS	Genes involved in Kinesins
1.4	18.7	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
1.4	22.5	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
1.4	29.0	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.4	23.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.4	19.0	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
1.3	13.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
1.3	17.3	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
1.3	59.0	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
1.3	55.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
1.3	11.3	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
1.2	40.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.2	28.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
1.2	19.9	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
1.2	31.5	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
1.1	43.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
1.1	29.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
1.1	3.3	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
1.1	17.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
1.1	8.6	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
1.0	63.3	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
1.0	34.6	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.9	31.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.9	15.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.8	43.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.8	22.7	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.8	4.9	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.8	5.3	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.8	8.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.8	40.7	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.7	17.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.7	12.6	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.7	13.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.6	8.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.6	14.7	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.6	94.3	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.6	13.8	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.6	15.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.6	20.0	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.5	23.1	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.5	21.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.5	8.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5	11.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.5	33.2	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.5	20.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.5	26.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.5	53.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.5	6.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.5	60.0	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.5	5.0	REACTOME GLOBAL GENOMIC NER GG NER	Genes involved in Global Genomic NER (GG-NER)
0.4	24.6	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.4	11.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.4	5.5	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.4	18.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.4	2.8	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.4	12.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.4	11.3	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.4	6.5	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.4	23.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	9.5	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.3	6.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.3	5.6	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.3	4.9	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.3	3.5	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.3	9.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.3	3.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3	2.3	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2	7.9	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2	5.6	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2	5.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	14.7	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.2	9.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	2.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	7.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	3.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	1.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	6.6	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	4.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	5.3	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	1.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	1.0	REACTOME DNA REPAIR	Genes involved in DNA Repair