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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for DDIT3

Z-value: 0.56

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Transcription factors associated with DDIT3

Gene Symbol Gene ID Gene Info
DDIT3
ENSG00000175197.6 DNA damage inducible transcript 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DDIT3hg19_v2_chr12_-_57914275_57914304-0.291.4e-05Click!

Activity profile of DDIT3 motif

Sorted Z-values of DDIT3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_17659234 11.81 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr9_+_112542591 9.60 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
PALM2
PALM2-AKAP2
AKAP2
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr9_-_95055956 9.38 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr9_+_110045537 9.06 ENST00000358015.3
RAD23B
RAD23 homolog B (S. cerevisiae)
chr10_-_17659357 8.35 ENST00000326961.6
ENST00000361271.3
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr9_+_112542572 8.29 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr5_+_72143988 7.37 ENST00000506351.2
TNPO1
transportin 1
chr3_+_157154578 7.10 ENST00000295927.3
PTX3
pentraxin 3, long
chr9_-_95056010 7.00 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr7_+_99006550 6.88 ENST00000222969.5
BUD31
BUD31 homolog (S. cerevisiae)
chr9_+_80912059 6.68 ENST00000347159.2
ENST00000376588.3
PSAT1
phosphoserine aminotransferase 1
chr5_-_137878887 6.05 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr7_+_99006232 5.89 ENST00000403633.2
BUD31
BUD31 homolog (S. cerevisiae)
chr19_+_12917364 5.89 ENST00000221486.4
RNASEH2A
ribonuclease H2, subunit A
chr19_+_33865218 5.84 ENST00000585933.2
CEBPG
CCAAT/enhancer binding protein (C/EBP), gamma
chr2_+_63816295 5.72 ENST00000539945.1
ENST00000544381.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr7_-_56101826 5.67 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr2_-_161350305 5.65 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr2_+_192141611 5.14 ENST00000392316.1
MYO1B
myosin IB
chr4_-_2935674 4.78 ENST00000514800.1
MFSD10
major facilitator superfamily domain containing 10
chr13_-_24007815 4.74 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr12_+_50144381 4.24 ENST00000552370.1
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr3_+_130569429 4.24 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr17_-_30228678 3.93 ENST00000261708.4
UTP6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr10_+_60028818 3.70 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr5_+_118812294 3.69 ENST00000509514.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr10_-_116444371 3.58 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr2_+_63816087 3.54 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr11_+_34073195 3.38 ENST00000341394.4
CAPRIN1
cell cycle associated protein 1
chr11_+_34073269 3.35 ENST00000389645.3
CAPRIN1
cell cycle associated protein 1
chr5_+_118812237 3.20 ENST00000513628.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr3_+_38017264 3.19 ENST00000436654.1
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr3_+_12392971 3.16 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr7_-_99006443 3.03 ENST00000350498.3
PDAP1
PDGFA associated protein 1
chr3_+_44840679 2.99 ENST00000425755.1
KIF15
kinesin family member 15
chr16_-_70323422 2.99 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr1_+_174844645 2.79 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr1_+_154229547 2.72 ENST00000428595.1
UBAP2L
ubiquitin associated protein 2-like
chr20_+_48807351 2.61 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr1_+_111770278 2.58 ENST00000369748.4
CHI3L2
chitinase 3-like 2
chr1_-_44820880 2.52 ENST00000372257.2
ENST00000457571.1
ENST00000452396.1
ERI3
ERI1 exoribonuclease family member 3
chr1_+_111770232 2.51 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chr12_-_52867569 2.46 ENST00000252250.6
KRT6C
keratin 6C
chr19_-_49258606 2.38 ENST00000310160.3
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr19_-_6604094 2.37 ENST00000597430.2
CD70
CD70 molecule
chr11_-_8680383 2.31 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr5_+_112074029 2.28 ENST00000512211.2
APC
adenomatous polyposis coli
chr1_+_150954493 2.23 ENST00000368947.4
ANXA9
annexin A9
chr22_+_31518938 1.94 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr12_-_53074182 1.89 ENST00000252244.3
KRT1
keratin 1
chr16_-_18908196 1.79 ENST00000565324.1
ENST00000561947.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr2_-_216300784 1.76 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr14_+_102276132 1.73 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chrX_-_133792480 1.62 ENST00000359237.4
PLAC1
placenta-specific 1
chr12_-_25102252 1.54 ENST00000261192.7
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr10_-_103874692 1.47 ENST00000361198.5
LDB1
LIM domain binding 1
chr10_-_92681033 1.45 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chrX_+_9431324 1.39 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr16_+_56970567 1.33 ENST00000563911.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr12_-_63328817 1.21 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr17_-_77813186 1.15 ENST00000448310.1
ENST00000269397.4
CBX4
chromobox homolog 4
chr2_-_179672142 1.14 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN
titin
chr17_+_4855053 0.76 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr1_+_169079823 0.71 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr12_-_25101920 0.65 ENST00000539780.1
ENST00000546285.1
ENST00000342945.5
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr9_+_70971815 0.58 ENST00000396392.1
ENST00000396396.1
PGM5
phosphoglucomutase 5
chr8_-_93029865 0.57 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_-_66492562 0.50 ENST00000256447.4
CD180
CD180 molecule
chr3_+_190105909 0.33 ENST00000456423.1
CLDN16
claudin 16
chrX_-_100129128 0.17 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr1_-_67519782 0.16 ENST00000235345.5
SLC35D1
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr20_+_54987305 0.11 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr20_+_54987168 0.07 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr5_-_54281407 0.07 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1

Network of associatons between targets according to the STRING database.

First level regulatory network of DDIT3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.4 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
2.0 5.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
1.6 12.8 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
1.4 7.1 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
1.3 6.7 GO:0042816 vitamin B6 metabolic process(GO:0042816)
1.1 6.9 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
1.0 3.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.8 3.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.8 9.3 GO:0006108 malate metabolic process(GO:0006108)
0.7 5.8 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.7 4.2 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.7 4.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.6 1.8 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.5 7.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.5 5.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.5 5.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.5 2.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.4 6.1 GO:0006449 regulation of translational termination(GO:0006449)
0.4 1.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.4 2.2 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.3 2.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.3 4.7 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.3 9.1 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.2 1.5 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.2 6.7 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.2 2.6 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 2.4 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2 0.7 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.2 3.7 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 1.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 4.8 GO:0015893 drug transport(GO:0015893)
0.1 1.9 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 3.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.5 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 1.6 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 1.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 16.5 GO:0008360 regulation of cell shape(GO:0008360)
0.1 2.5 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 3.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.6 GO:0019388 galactose catabolic process(GO:0019388)
0.0 5.1 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.2 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.0 2.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 3.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 3.2 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 1.8 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.8 GO:0061615 NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 1.4 GO:0016575 histone deacetylation(GO:0016575)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0005873 plus-end kinesin complex(GO:0005873)
0.8 3.9 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.8 16.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.7 4.7 GO:0070852 cell body fiber(GO:0070852)
0.5 9.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.2 2.3 GO:1990909 Wnt signalosome(GO:1990909)
0.2 2.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 6.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 6.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 4.4 GO:0045095 keratin filament(GO:0045095)
0.1 7.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 6.3 GO:0016459 myosin complex(GO:0016459)
0.1 10.5 GO:0034399 nuclear periphery(GO:0034399)
0.1 12.8 GO:0005681 spliceosomal complex(GO:0005681)
0.0 4.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.3 GO:0016235 aggresome(GO:0016235)
0.0 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 2.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 3.0 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.0 3.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 4.2 GO:0043209 myelin sheath(GO:0043209)
0.0 2.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.4 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
1.9 9.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
1.2 5.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.1 6.9 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
1.1 5.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.0 6.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
1.0 3.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.9 7.1 GO:0001849 complement component C1q binding(GO:0001849)
0.7 4.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.5 1.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.5 5.1 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.4 8.9 GO:0008483 transaminase activity(GO:0008483)
0.4 4.8 GO:0019534 toxin transporter activity(GO:0019534)
0.4 3.2 GO:0050692 DBD domain binding(GO:0050692)
0.2 4.7 GO:0070628 proteasome binding(GO:0070628)
0.2 5.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 9.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 12.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 1.9 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.2 7.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 3.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 5.8 GO:0008301 DNA binding, bending(GO:0008301)
0.2 2.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.2 2.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 4.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 3.9 GO:0030515 snoRNA binding(GO:0030515)
0.1 1.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.1 GO:0031433 telethonin binding(GO:0031433)
0.1 2.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 2.2 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.1 1.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 1.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 2.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 5.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 1.1 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 4.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.2 GO:0004527 exonuclease activity(GO:0004527)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 16.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.2 9.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 3.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.6 PID IL3 PATHWAY IL3-mediated signaling events
0.1 3.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 3.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 19.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.4 12.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.4 7.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.4 6.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.3 9.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.2 10.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.8 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 3.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 3.0 REACTOME KINESINS Genes involved in Kinesins
0.1 5.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 7.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 7.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression