Project

GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for EOMES

Z-value: 1.04

Motif logo

Transcription factors associated with EOMES

Gene Symbol Gene ID Gene Info
ENSG00000163508.8 eomesodermin

Activity profile of EOMES motif

Sorted Z-values of EOMES motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_55658252 24.21 ENST00000395425.2
discs, large (Drosophila) homolog-associated protein 5
chr9_+_91926103 23.75 ENST00000314355.6
CDC28 protein kinase regulatory subunit 2
chr14_-_55658323 20.83 ENST00000554067.1
ENST00000247191.2
discs, large (Drosophila) homolog-associated protein 5
chr7_-_96339132 19.10 ENST00000413065.1
split hand/foot malformation (ectrodactyly) type 1
chr6_+_34204642 18.64 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr1_-_167906277 16.99 ENST00000271373.4
mitochondrial pyruvate carrier 2
chr14_+_54863739 16.64 ENST00000541304.1
cyclin-dependent kinase inhibitor 3
chr1_+_87170577 16.48 ENST00000482504.1
SH3-domain GRB2-like endophilin B1
chr1_+_162531294 16.26 ENST00000367926.4
ENST00000271469.3
UDP-N-acteylglucosamine pyrophosphorylase 1
chr10_-_58120996 16.26 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZW10 interacting kinetochore protein
chr1_-_193029192 15.36 ENST00000417752.1
ENST00000367452.4
ubiquitin carboxyl-terminal hydrolase L5
chr11_-_57103327 14.30 ENST00000529002.1
ENST00000278412.2
structure specific recognition protein 1
chr11_+_64808675 13.99 ENST00000529996.1
SAC3 domain containing 1
chr2_-_161350305 13.89 ENST00000348849.3
RNA binding motif, single stranded interacting protein 1
chr7_-_99698338 13.59 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr19_+_35645817 13.36 ENST00000423817.3
FXYD domain containing ion transport regulator 5
chr3_-_167452262 12.88 ENST00000487947.2
programmed cell death 10
chr7_+_87505544 12.00 ENST00000265728.1
DBF4 homolog (S. cerevisiae)
chr11_-_66056596 11.64 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
Yip1 interacting factor homolog A (S. cerevisiae)
chr8_-_109260897 11.58 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
eukaryotic translation initiation factor 3, subunit E
chr12_+_54378923 11.31 ENST00000303460.4
homeobox C10
chr19_+_35645618 11.28 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD domain containing ion transport regulator 5
chr7_-_96339167 11.16 ENST00000444799.1
ENST00000417009.1
ENST00000248566.2
split hand/foot malformation (ectrodactyly) type 1
chr3_-_167452298 10.68 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
programmed cell death 10
chr3_-_182698381 10.48 ENST00000292782.4
DCN1, defective in cullin neddylation 1, domain containing 1
chr13_+_28195988 10.42 ENST00000399697.3
ENST00000399696.1
polymerase (RNA) I polypeptide D, 16kDa
chr22_+_40742512 10.40 ENST00000454266.2
ENST00000342312.6
adenylosuccinate lyase
chr11_-_102323489 10.40 ENST00000361236.3
transmembrane protein 123
chr19_+_16178317 10.36 ENST00000344824.6
ENST00000538887.1
tropomyosin 4
chr19_+_49496705 10.10 ENST00000595090.1
RuvB-like AAA ATPase 2
chr11_-_107729887 9.99 ENST00000525815.1
solute carrier family 35, member F2
chr7_-_93520259 9.91 ENST00000222543.5
tissue factor pathway inhibitor 2
chr3_-_131221790 9.85 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
mitochondrial ribosomal protein L3
chr5_+_32531893 9.82 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr1_+_43148625 9.62 ENST00000436427.1
Y box binding protein 1
chrX_+_21958814 9.61 ENST00000379404.1
ENST00000415881.2
spermine synthase
chr20_-_57617831 9.55 ENST00000371033.5
ENST00000355937.4
slowmo homolog 2 (Drosophila)
chrX_+_21958674 9.54 ENST00000404933.2
spermine synthase
chr11_+_64808368 9.45 ENST00000531072.1
ENST00000398846.1
SAC3 domain containing 1
chr1_+_43148059 9.29 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr22_+_40742497 9.29 ENST00000216194.7
adenylosuccinate lyase
chr2_+_201936707 9.27 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr18_-_47017956 9.18 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32 readthrough
ribosomal protein L17
chr13_+_28194873 8.80 ENST00000302979.3
polymerase (RNA) I polypeptide D, 16kDa
chr11_-_33757950 8.68 ENST00000533403.1
ENST00000528700.1
ENST00000527577.1
ENST00000395850.3
ENST00000351554.3
CD59 molecule, complement regulatory protein
chr1_+_19578033 8.65 ENST00000330263.4
mRNA turnover 4 homolog (S. cerevisiae)
chr2_+_201170770 8.58 ENST00000409988.3
ENST00000409385.1
spermatogenesis associated, serine-rich 2-like
chr4_-_183838596 8.54 ENST00000508994.1
ENST00000512766.1
dCMP deaminase
chr19_+_49496782 8.39 ENST00000601968.1
ENST00000596837.1
RuvB-like AAA ATPase 2
chr19_+_33865218 8.29 ENST00000585933.2
CCAAT/enhancer binding protein (C/EBP), gamma
chr11_+_34073269 7.99 ENST00000389645.3
cell cycle associated protein 1
chrX_-_114953669 7.95 ENST00000449327.1
Uncharacterized protein
chr2_+_201171242 7.91 ENST00000360760.5
spermatogenesis associated, serine-rich 2-like
chr11_+_65686728 7.88 ENST00000312515.2
ENST00000525501.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr8_-_124408652 7.88 ENST00000287394.5
ATPase family, AAA domain containing 2
chr1_-_245027833 7.85 ENST00000444376.2
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr11_+_35201826 7.81 ENST00000531873.1
CD44 molecule (Indian blood group)
chr7_+_16685756 7.71 ENST00000415365.1
ENST00000258761.3
ENST00000433922.2
ENST00000452975.2
ENST00000405202.1
basic leucine zipper and W2 domains 2
chr9_+_110045537 7.69 ENST00000358015.3
RAD23 homolog B (S. cerevisiae)
chr5_+_52083730 7.67 ENST00000282588.6
ENST00000274311.2
integrin, alpha 1
pelota homolog (Drosophila)
chr13_-_113862401 7.66 ENST00000375459.1
PCI domain containing 2
chr11_+_111896320 7.64 ENST00000531306.1
ENST00000537636.1
dihydrolipoamide S-acetyltransferase
chr6_-_131949200 7.57 ENST00000539158.1
ENST00000368058.1
mediator complex subunit 23
chr7_-_93519471 7.56 ENST00000451238.1
tissue factor pathway inhibitor 2
chr11_-_102323740 7.53 ENST00000398136.2
transmembrane protein 123
chr1_-_167906020 7.49 ENST00000458574.1
mitochondrial pyruvate carrier 2
chr3_-_167452614 7.42 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
programmed cell death 10
chr7_-_93520191 7.35 ENST00000545378.1
tissue factor pathway inhibitor 2
chr7_+_156931606 7.29 ENST00000348165.5
ubiquitin protein ligase E3C
chr8_-_101734308 7.26 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
poly(A) binding protein, cytoplasmic 1
chr1_-_31769656 7.24 ENST00000446633.2
small nuclear ribonucleoprotein 40kDa (U5)
chrX_+_118602363 7.17 ENST00000317881.8
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr4_+_17812525 7.12 ENST00000251496.2
non-SMC condensin I complex, subunit G
chr8_-_117778494 7.11 ENST00000276682.4
eukaryotic translation initiation factor 3, subunit H
chr16_+_30064444 7.05 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
aldolase A, fructose-bisphosphate
chr11_+_65686802 7.02 ENST00000376991.2
DR1-associated protein 1 (negative cofactor 2 alpha)
chr2_-_69664549 7.01 ENST00000450796.2
ENST00000484177.1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr11_+_34073757 6.92 ENST00000532820.1
cell cycle associated protein 1
chr8_-_90996837 6.92 ENST00000519426.1
ENST00000265433.3
nibrin
chr2_-_9770706 6.87 ENST00000381844.4
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
chr1_-_245027766 6.85 ENST00000283179.9
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr5_-_133968529 6.76 ENST00000402673.2
SAR1 homolog B (S. cerevisiae)
chr1_-_31769595 6.72 ENST00000263694.4
small nuclear ribonucleoprotein 40kDa (U5)
chr3_-_167452703 6.70 ENST00000497056.2
ENST00000473645.2
programmed cell death 10
chr8_-_103668114 6.68 ENST00000285407.6
Kruppel-like factor 10
chr11_+_112097069 6.56 ENST00000280362.3
ENST00000525803.1
6-pyruvoyltetrahydropterin synthase
chrX_+_150151752 6.45 ENST00000325307.7
high mobility group box 3
chr3_+_196466710 6.45 ENST00000327134.3
p21 protein (Cdc42/Rac)-activated kinase 2
chr13_+_29233218 6.41 ENST00000380842.4
proteasome maturation protein
chr11_+_73498898 6.39 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
mitochondrial ribosomal protein L48
chr16_-_67693846 6.34 ENST00000602850.1
adrenocortical dysplasia homolog (mouse)
chr6_-_131277510 6.33 ENST00000525193.1
ENST00000527659.1
erythrocyte membrane protein band 4.1-like 2
chr1_-_246729544 6.29 ENST00000544618.1
ENST00000366514.4
transcription factor B2, mitochondrial
chr7_+_94285637 6.26 ENST00000482108.1
ENST00000488574.1
paternally expressed 10
chr22_-_18257178 6.24 ENST00000342111.5
BH3 interacting domain death agonist
chr2_-_179315786 6.23 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
protein kinase, interferon-inducible double stranded RNA dependent activator
chr1_+_218458625 6.14 ENST00000366932.3
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr11_+_111896090 6.14 ENST00000393051.1
dihydrolipoamide S-acetyltransferase
chr3_-_123710893 6.13 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
rhophilin associated tail protein 1
chr2_+_201170596 6.04 ENST00000439084.1
ENST00000409718.1
spermatogenesis associated, serine-rich 2-like
chr1_-_244615425 6.03 ENST00000366535.3
adenylosuccinate synthase
chr10_+_75910960 6.02 ENST00000539909.1
ENST00000286621.2
adenosine kinase
chr22_+_38071615 6.00 ENST00000215909.5
lectin, galactoside-binding, soluble, 1
chr15_+_48623208 5.92 ENST00000559935.1
ENST00000559416.1
deoxyuridine triphosphatase
chr12_-_56709674 5.92 ENST00000551286.1
ENST00000549318.1
canopy FGF signaling regulator 2
Uncharacterized protein
chr4_+_169418195 5.91 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr2_-_179315453 5.87 ENST00000432031.2
protein kinase, interferon-inducible double stranded RNA dependent activator
chr17_+_33914460 5.82 ENST00000537622.2
adaptor-related protein complex 2, beta 1 subunit
chr2_-_69664586 5.81 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr2_-_179315490 5.73 ENST00000487082.1
protein kinase, interferon-inducible double stranded RNA dependent activator
chr17_-_61850894 5.67 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
coiled-coil domain containing 47
chr22_-_39096661 5.61 ENST00000216039.5
Josephin domain containing 1
chr11_-_62439012 5.56 ENST00000532208.1
ENST00000377954.2
ENST00000415855.2
ENST00000431002.2
ENST00000354588.3
chromosome 11 open reading frame 48
chr3_+_125687987 5.56 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
rhophilin associated tail protein 1B
chr3_-_127842612 5.52 ENST00000417360.1
ENST00000322623.5
RuvB-like AAA ATPase 1
chr2_+_201171372 5.52 ENST00000409140.3
spermatogenesis associated, serine-rich 2-like
chr15_-_90777277 5.49 ENST00000328649.6
calcium and integrin binding 1 (calmyrin)
chr16_+_30064411 5.46 ENST00000338110.5
aldolase A, fructose-bisphosphate
chr1_-_33283754 5.42 ENST00000373477.4
tyrosyl-tRNA synthetase
chr1_-_207095212 5.41 ENST00000420007.2
Fas apoptotic inhibitory molecule 3
chr9_+_115983808 5.40 ENST00000374210.6
ENST00000374212.4
solute carrier family 31 (copper transporter), member 1
chr18_-_47018869 5.38 ENST00000583036.1
ENST00000580261.1
ribosomal protein L17
chr13_-_31191642 5.38 ENST00000405805.1
high mobility group box 1
chr15_-_56285742 5.25 ENST00000435532.3
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr6_-_35888824 5.21 ENST00000361690.3
ENST00000512445.1
SRSF protein kinase 1
chr1_-_207095324 5.17 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr16_+_29817841 5.15 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chrX_+_131157322 5.14 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
Serine/threonine-protein kinase MST4
chrX_+_150151824 5.07 ENST00000455596.1
ENST00000448905.2
high mobility group box 3
chrX_+_131157290 5.07 ENST00000394334.2
Serine/threonine-protein kinase MST4
chr10_+_106014468 4.99 ENST00000369710.4
ENST00000369713.5
ENST00000445155.1
glutathione S-transferase omega 1
chr2_-_170430277 4.97 ENST00000438035.1
ENST00000453929.2
FAST kinase domains 1
chr3_-_125239010 4.95 ENST00000536067.1
ENST00000251775.4
sorting nexin 4
chrX_+_77359726 4.86 ENST00000442431.1
phosphoglycerate kinase 1
chr11_+_34073195 4.85 ENST00000341394.4
cell cycle associated protein 1
chr17_+_33914276 4.79 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr18_-_19284724 4.77 ENST00000580981.1
ENST00000289119.2
abhydrolase domain containing 3
chr15_+_48623600 4.75 ENST00000558813.1
ENST00000331200.3
ENST00000558472.1
deoxyuridine triphosphatase
chr8_-_90996459 4.69 ENST00000517337.1
ENST00000409330.1
nibrin
chr20_+_1099233 4.63 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr20_-_34252759 4.57 ENST00000414711.1
ENST00000416778.1
ENST00000397442.1
ENST00000440240.1
ENST00000412056.1
ENST00000352393.4
ENST00000458038.1
ENST00000420363.1
ENST00000434795.1
ENST00000437100.1
ENST00000414664.1
ENST00000359646.1
ENST00000424458.1
ENST00000374104.3
ENST00000374114.3
copine I
RNA binding motif protein 12
chr2_-_219134343 4.57 ENST00000447885.1
ENST00000420660.1
angio-associated, migratory cell protein
chr6_-_75953484 4.53 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr1_-_153949751 4.48 ENST00000428469.1
jumping translocation breakpoint
chr8_+_144099896 4.43 ENST00000292494.6
ENST00000429120.2
lymphocyte antigen 6 complex, locus E
chr17_-_1588101 4.32 ENST00000577001.1
ENST00000572621.1
ENST00000304992.6
pre-mRNA processing factor 8
chr6_-_109703634 4.32 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164 molecule, sialomucin
chr7_+_55177416 4.28 ENST00000450046.1
ENST00000454757.2
epidermal growth factor receptor
chr10_+_85899196 4.28 ENST00000372134.3
growth hormone inducible transmembrane protein
chr22_-_42486747 4.25 ENST00000602404.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
chr1_+_167906056 4.25 ENST00000367840.3
DDB1 and CUL4 associated factor 6
chr15_+_89182178 4.23 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr4_-_54930790 4.18 ENST00000263921.3
cysteine-rich hydrophobic domain 2
chr2_+_99953816 4.17 ENST00000289371.6
eukaryotic translation initiation factor 5B
chr8_-_117768023 4.15 ENST00000518949.1
ENST00000522453.1
ENST00000521861.1
ENST00000518995.1
eukaryotic translation initiation factor 3, subunit H
chr8_+_144099914 4.13 ENST00000521699.1
ENST00000520531.1
ENST00000520466.1
ENST00000521003.1
ENST00000522528.1
ENST00000522971.1
ENST00000519611.1
ENST00000521182.1
ENST00000519546.1
ENST00000523847.1
ENST00000522024.1
lymphocyte antigen 6 complex, locus E
chr15_-_85259294 4.08 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
SEC11 homolog A (S. cerevisiae)
chr19_+_19303008 4.08 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
regulatory factor X-associated ankyrin-containing protein
chr11_+_63706444 4.03 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr19_+_13261216 4.00 ENST00000587885.1
ENST00000292433.3
immediate early response 2
chr14_-_24682652 3.99 ENST00000556387.1
ENST00000530611.1
ENST00000609024.1
ENST00000530996.1
transmembrane 9 superfamily member 1
Transmembrane 9 superfamily member 1
charged multivesicular body protein 4A
chr1_+_186344883 3.98 ENST00000367470.3
chromosome 1 open reading frame 27
chr1_+_186344945 3.96 ENST00000419367.3
ENST00000287859.6
chromosome 1 open reading frame 27
chrX_-_102757802 3.94 ENST00000372633.1
RAB40A, member RAS oncogene family
chr19_-_2427536 3.91 ENST00000591871.1
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr1_-_205744205 3.89 ENST00000446390.2
RAB7, member RAS oncogene family-like 1
chr9_-_117853297 3.83 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
tenascin C
chr3_+_133292574 3.79 ENST00000264993.3
CDV3 homolog (mouse)
chr6_-_74233480 3.77 ENST00000455918.1
eukaryotic translation elongation factor 1 alpha 1
chr14_-_51135036 3.77 ENST00000324679.4
salvador homolog 1 (Drosophila)
chr16_+_202686 3.73 ENST00000252951.2
hemoglobin, zeta
chr10_-_94333784 3.72 ENST00000265986.6
insulin-degrading enzyme
chr11_+_69455855 3.72 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr17_-_15587602 3.68 ENST00000416464.2
ENST00000578237.1
ENST00000581200.1
tripartite motif containing 16
chr19_+_34856141 3.66 ENST00000586425.1
glucose-6-phosphate isomerase
chr4_-_144940477 3.53 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
glycophorin B (MNS blood group)
chr6_-_111927062 3.52 ENST00000359831.4
TRAF3 interacting protein 2
chr13_+_73302047 3.52 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
bora, aurora kinase A activator
chr19_+_9938562 3.52 ENST00000586895.1
ENST00000358666.3
ENST00000590068.1
ENST00000593087.1
ubiquitin-like 5
chr1_-_184943610 3.48 ENST00000367511.3
family with sequence similarity 129, member A
chr9_+_140172200 3.47 ENST00000357503.2
torsin family 4, member A
chr15_-_85259330 3.46 ENST00000560266.1
SEC11 homolog A (S. cerevisiae)
chr15_-_85259384 3.45 ENST00000455959.3
SEC11 homolog A (S. cerevisiae)
chr2_-_65357225 3.44 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A, member RAS oncogene family
chr1_-_153950098 3.38 ENST00000356648.1
jumping translocation breakpoint
chr5_+_96212185 3.37 ENST00000379904.4
endoplasmic reticulum aminopeptidase 2
chr2_-_54197915 3.31 ENST00000404125.1
proteasome (prosome, macropain) activator subunit 4
chr17_-_77813186 3.29 ENST00000448310.1
ENST00000269397.4
chromobox homolog 4
chr19_-_3061397 3.22 ENST00000586839.1
amino-terminal enhancer of split
chr1_-_205744574 3.21 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7, member RAS oncogene family-like 1
chr7_+_129710350 3.21 ENST00000335420.5
ENST00000463413.1
kelch domain containing 10
chr6_-_109702885 3.16 ENST00000504373.1
CD164 molecule, sialomucin
chr20_-_34252847 3.15 ENST00000317619.3
ENST00000397446.1
ENST00000397445.1
ENST00000397443.1
ENST00000430570.1
ENST00000439806.2
ENST00000437340.1
ENST00000435161.1
ENST00000431148.1
copine I
RNA binding motif protein 12
chr9_+_37486005 3.14 ENST00000377792.3
polymerase (RNA) I polypeptide E, 53kDa
chr4_-_151936865 3.13 ENST00000535741.1
LPS-responsive vesicle trafficking, beach and anchor containing
chr1_-_153950116 3.09 ENST00000368589.1
jumping translocation breakpoint
chr19_+_55897699 3.08 ENST00000558131.1
ENST00000558752.1
ENST00000458349.2
ribosomal protein L28
chr19_-_49496557 3.08 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
glycogen synthase 1 (muscle)
chr17_+_48133459 3.07 ENST00000320031.8
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr3_+_111805182 3.01 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
chromosome 3 open reading frame 52

Network of associatons between targets according to the STRING database.

First level regulatory network of EOMES

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 25.7 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
8.2 24.6 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
7.5 37.7 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
7.5 45.0 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
6.4 19.2 GO:0006597 spermine biosynthetic process(GO:0006597)
6.1 24.5 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
4.8 33.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
4.7 18.6 GO:0090402 oncogene-induced cell senescence(GO:0090402)
4.6 18.5 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
4.1 16.5 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
3.6 10.7 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
3.1 9.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.1 9.2 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
2.9 11.6 GO:0031860 telomeric 3' overhang formation(GO:0031860)
2.5 5.0 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
2.2 8.7 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
2.1 8.5 GO:0006226 dUMP biosynthetic process(GO:0006226)
2.1 10.6 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
2.0 6.0 GO:0044209 AMP salvage(GO:0044209)
1.8 5.5 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
1.6 6.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
1.6 4.7 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
1.6 14.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.5 7.7 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.5 6.0 GO:0002317 plasma cell differentiation(GO:0002317)
1.4 4.3 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
1.4 17.8 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
1.3 5.4 GO:0002424 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
1.3 5.3 GO:0044111 development involved in symbiotic interaction(GO:0044111)
1.3 11.6 GO:1902416 positive regulation of mRNA binding(GO:1902416)
1.3 7.7 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.3 3.8 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
1.3 11.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
1.3 16.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
1.2 3.7 GO:1901143 insulin catabolic process(GO:1901143)
1.2 3.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
1.2 7.2 GO:1901029 adenine transport(GO:0015853) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
1.1 4.5 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
1.1 17.9 GO:0045793 positive regulation of cell size(GO:0045793)
1.1 5.3 GO:0072719 cellular response to cisplatin(GO:0072719)
1.0 8.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
1.0 4.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
1.0 2.1 GO:2000078 positive regulation of type B pancreatic cell development(GO:2000078)
1.0 7.8 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.0 15.4 GO:0021670 lateral ventricle development(GO:0021670)
0.9 8.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.8 5.0 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.8 7.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.8 4.0 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.8 2.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.7 2.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.7 6.6 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.7 2.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.7 7.0 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.7 10.5 GO:0045116 protein neddylation(GO:0045116)
0.7 2.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.7 2.7 GO:0072183 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.7 7.4 GO:0006983 ER overload response(GO:0006983)
0.7 2.0 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.7 11.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.7 5.9 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.6 5.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.6 7.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.6 19.8 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.6 1.9 GO:0060535 trachea cartilage morphogenesis(GO:0060535) renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.6 13.8 GO:0006465 signal peptide processing(GO:0006465)
0.6 2.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.6 27.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.6 18.2 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.6 12.8 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.6 1.7 GO:0006404 RNA import into nucleus(GO:0006404)
0.5 1.6 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.5 3.1 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.5 3.6 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.5 3.0 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.5 19.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.5 2.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.5 1.4 GO:0040031 snRNA modification(GO:0040031)
0.5 1.9 GO:0098838 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.5 1.9 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.5 1.8 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.5 6.4 GO:0043248 proteasome assembly(GO:0043248)
0.5 6.3 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.4 7.9 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.4 1.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.4 3.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.4 3.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.4 1.6 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.4 5.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4 8.7 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.3 1.4 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.3 2.8 GO:0044351 macropinocytosis(GO:0044351)
0.3 2.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.3 2.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3 5.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 7.1 GO:0003334 keratinocyte development(GO:0003334)
0.3 1.5 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.3 0.9 GO:0019858 cytosine metabolic process(GO:0019858)
0.3 3.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 3.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 3.7 GO:0015671 oxygen transport(GO:0015671)
0.3 0.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.3 22.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.3 16.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.3 6.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 10.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.3 1.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.3 2.3 GO:0034214 protein hexamerization(GO:0034214)
0.3 2.8 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 15.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 4.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.2 3.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 1.9 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 3.8 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 3.8 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.2 2.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 11.5 GO:0032392 DNA geometric change(GO:0032392)
0.2 1.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.2 1.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 2.5 GO:0051451 myoblast migration(GO:0051451)
0.2 16.2 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.2 2.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 1.8 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2 2.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 1.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 3.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 0.8 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 5.2 GO:0031639 plasminogen activation(GO:0031639)
0.2 5.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 4.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 1.6 GO:0070828 heterochromatin organization(GO:0070828)
0.2 0.5 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.2 15.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.2 19.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 0.9 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 2.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 3.5 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 3.5 GO:0001783 B cell apoptotic process(GO:0001783)
0.1 1.5 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.1 12.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 1.4 GO:0010225 response to UV-C(GO:0010225)
0.1 2.5 GO:0036260 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.1 7.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 2.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 3.1 GO:0097062 dendritic spine maintenance(GO:0097062) renal filtration(GO:0097205)
0.1 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 1.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 2.5 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 1.1 GO:0014041 regulation of neuron maturation(GO:0014041)
0.1 0.8 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.8 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 1.8 GO:0006020 inositol metabolic process(GO:0006020)
0.1 2.8 GO:0030488 tRNA methylation(GO:0030488)
0.1 6.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 11.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 4.8 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.3 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 0.6 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 11.8 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.1 1.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 8.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 4.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 1.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 6.9 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.4 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 6.2 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1 3.9 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 0.3 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.1 0.6 GO:0016255 polyol transport(GO:0015791) attachment of GPI anchor to protein(GO:0016255)
0.1 2.5 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 1.1 GO:0031053 primary miRNA processing(GO:0031053)
0.1 1.0 GO:0070986 left/right axis specification(GO:0070986)
0.1 3.7 GO:0006119 oxidative phosphorylation(GO:0006119)
0.1 0.4 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 1.8 GO:0002360 T cell lineage commitment(GO:0002360)
0.1 1.8 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 0.7 GO:0070673 response to interleukin-18(GO:0070673)
0.1 0.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 3.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.8 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.3 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.6 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 4.7 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 3.2 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.1 0.9 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.8 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.0 2.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.0 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 2.6 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.8 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.3 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 1.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0051182 coenzyme transport(GO:0051182)
0.0 1.2 GO:0006270 DNA replication initiation(GO:0006270)
0.0 3.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 1.8 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:1905066 arterial endothelial cell fate commitment(GO:0060844) canonical Wnt signaling pathway involved in heart development(GO:0061316) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 1.1 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 1.7 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.8 GO:0003016 respiratory system process(GO:0003016)
0.0 2.4 GO:0045333 cellular respiration(GO:0045333)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 1.2 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 5.7 GO:0006260 DNA replication(GO:0006260)
0.0 0.2 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 1.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 11.3 GO:0051301 cell division(GO:0051301)
0.0 0.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0032962 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.2 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.5 GO:0006915 apoptotic process(GO:0006915)
0.0 0.1 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 0.3 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.8 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
3.4 33.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
3.1 3.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
2.6 45.0 GO:0031616 spindle pole centrosome(GO:0031616)
2.6 7.7 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
2.6 25.5 GO:0097255 R2TP complex(GO:0097255)
2.0 13.8 GO:0005787 signal peptidase complex(GO:0005787)
1.7 18.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.7 11.6 GO:0030870 Mre11 complex(GO:0030870)
1.4 7.2 GO:0071817 MMXD complex(GO:0071817)
1.4 4.3 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
1.3 23.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
1.3 11.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
1.3 11.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.1 9.2 GO:0070187 telosome(GO:0070187)
1.1 7.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.1 5.4 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
1.0 16.8 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.0 13.6 GO:0042555 MCM complex(GO:0042555)
0.9 12.3 GO:0070578 RISC-loading complex(GO:0070578)
0.9 24.5 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.8 2.4 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.7 11.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.7 7.1 GO:0000796 condensin complex(GO:0000796)
0.7 2.1 GO:0044305 calyx of Held(GO:0044305)
0.6 14.0 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.6 2.4 GO:0032279 asymmetric synapse(GO:0032279)
0.6 3.0 GO:0089701 U2AF(GO:0089701)
0.6 10.6 GO:0030122 AP-2 adaptor complex(GO:0030122) endolysosome membrane(GO:0036020)
0.5 10.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.5 8.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 20.5 GO:0000421 autophagosome membrane(GO:0000421)
0.5 1.5 GO:0033565 ESCRT-0 complex(GO:0033565)
0.5 27.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.5 3.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.5 1.8 GO:0032044 DSIF complex(GO:0032044)
0.5 6.3 GO:0008091 spectrin(GO:0008091)
0.5 7.7 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.4 3.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.4 27.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 13.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.4 3.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 16.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4 3.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 13.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.4 2.2 GO:0001740 Barr body(GO:0001740)
0.3 3.8 GO:0005614 interstitial matrix(GO:0005614)
0.3 2.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 15.1 GO:0031430 M band(GO:0031430)
0.3 2.3 GO:0032059 bleb(GO:0032059)
0.3 5.5 GO:0032433 filopodium tip(GO:0032433)
0.3 6.2 GO:0030056 hemidesmosome(GO:0030056)
0.3 3.7 GO:0005833 hemoglobin complex(GO:0005833)
0.3 1.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 2.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.3 3.6 GO:0036038 MKS complex(GO:0036038)
0.3 1.8 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.2 3.7 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.2 15.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 6.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 6.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 5.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 20.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 4.6 GO:0005839 proteasome core complex(GO:0005839)
0.2 10.1 GO:0015030 Cajal body(GO:0015030)
0.2 6.5 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.2 5.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 7.3 GO:0000502 proteasome complex(GO:0000502)
0.1 7.1 GO:0002102 podosome(GO:0002102)
0.1 15.1 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.1 4.8 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 1.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.1 GO:0031941 filamentous actin(GO:0031941)
0.1 7.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 1.8 GO:0000786 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.1 1.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 2.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 8.1 GO:0005694 chromosome(GO:0005694)
0.1 4.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 30.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 1.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 2.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 3.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.5 GO:0001739 sex chromatin(GO:0001739)
0.1 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 5.4 GO:0000793 condensed chromosome(GO:0000793)
0.1 4.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 5.7 GO:0001650 fibrillar center(GO:0001650)
0.0 13.7 GO:0005819 spindle(GO:0005819)
0.0 2.1 GO:0030175 filopodium(GO:0030175)
0.0 3.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 2.0 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 3.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 6.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.9 GO:0043209 myelin sheath(GO:0043209)
0.0 1.2 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 5.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 3.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 10.6 GO:0005730 nucleolus(GO:0005730)
0.0 8.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.8 GO:0016418 S-acetyltransferase activity(GO:0016418)
4.0 24.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
3.6 10.7 GO:0004170 dUTP diphosphatase activity(GO:0004170)
3.4 23.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
3.1 9.3 GO:0008859 exoribonuclease II activity(GO:0008859)
3.1 24.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
3.0 24.4 GO:0016842 amidine-lyase activity(GO:0016842)
2.2 6.6 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
2.1 8.5 GO:0004132 dCMP deaminase activity(GO:0004132)
2.0 6.0 GO:0048030 disaccharide binding(GO:0048030)
2.0 17.8 GO:0070883 pre-miRNA binding(GO:0070883)
1.8 10.9 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
1.8 7.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
1.7 5.0 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
1.6 4.9 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
1.5 7.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
1.5 16.3 GO:0070569 uridylyltransferase activity(GO:0070569)
1.4 4.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
1.3 18.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
1.3 23.7 GO:0001054 RNA polymerase I activity(GO:0001054)
1.3 2.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.3 6.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.2 3.7 GO:0032089 NACHT domain binding(GO:0032089)
1.2 3.7 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
1.1 23.3 GO:0070628 proteasome binding(GO:0070628)
1.1 11.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.0 5.0 GO:1990460 leptin receptor binding(GO:1990460)
1.0 4.8 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.9 4.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.8 4.0 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.8 2.3 GO:0070546 phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.8 5.3 GO:0050815 phosphoserine binding(GO:0050815)
0.7 2.9 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.7 2.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.7 2.0 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.6 25.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.6 19.8 GO:0008301 DNA binding, bending(GO:0008301)
0.6 6.3 GO:0042731 PH domain binding(GO:0042731)
0.6 2.5 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.6 3.0 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.6 2.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.6 10.5 GO:0097602 cullin family protein binding(GO:0097602)
0.5 1.6 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.5 5.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.5 5.4 GO:0045545 syndecan binding(GO:0045545)
0.5 6.0 GO:0042301 phosphate ion binding(GO:0042301)
0.5 2.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.5 1.9 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.5 9.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.5 10.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.5 1.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.5 1.9 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.5 3.7 GO:0043559 insulin binding(GO:0043559)
0.4 69.4 GO:0047485 protein N-terminus binding(GO:0047485)
0.4 50.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.4 2.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.4 9.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.4 11.9 GO:0070034 telomerase RNA binding(GO:0070034)
0.4 3.6 GO:0008158 hedgehog receptor activity(GO:0008158)
0.4 2.4 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.4 21.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.4 1.8 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.3 10.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 6.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 2.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3 12.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.3 7.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 3.5 GO:0031386 protein tag(GO:0031386)
0.3 15.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 3.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 1.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.3 2.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.3 24.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 2.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3 3.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.3 8.7 GO:0001848 complement binding(GO:0001848)
0.3 3.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 7.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 4.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 4.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.2 6.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 2.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 5.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 1.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.2 1.5 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 3.7 GO:0019206 nucleoside kinase activity(GO:0019206)
0.2 7.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 2.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 9.2 GO:0000049 tRNA binding(GO:0000049)
0.2 15.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 2.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.2 9.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 0.8 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.2 6.2 GO:0005123 death receptor binding(GO:0005123)
0.2 5.1 GO:0030506 ankyrin binding(GO:0030506)
0.2 0.5 GO:0003883 CTP synthase activity(GO:0003883)
0.2 3.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 2.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 3.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 12.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 3.1 GO:0001968 fibronectin binding(GO:0001968)
0.1 4.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 29.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 23.2 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 10.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.2 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 2.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 4.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 2.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.7 GO:0043495 protein anchor(GO:0043495)
0.1 1.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 5.0 GO:0003682 chromatin binding(GO:0003682)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 2.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 1.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 1.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 1.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 2.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.2 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 3.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 1.9 GO:0005109 frizzled binding(GO:0005109)
0.1 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 6.3 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 10.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 8.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.1 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 2.2 GO:0051117 ATPase binding(GO:0051117)
0.0 1.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 10.9 GO:0045296 cadherin binding(GO:0045296)
0.0 2.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.6 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.1 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0030170 pyridoxal phosphate binding(GO:0030170)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 41.3 PID AURORA A PATHWAY Aurora A signaling
0.6 89.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.4 6.4 PID MYC PATHWAY C-MYC pathway
0.4 8.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 17.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.3 1.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 3.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 1.5 PID IL5 PATHWAY IL5-mediated signaling events
0.3 22.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 14.0 PID ATR PATHWAY ATR signaling pathway
0.2 2.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 8.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 23.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.2 7.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 3.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 5.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 3.3 PID IL3 PATHWAY IL3-mediated signaling events
0.2 8.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.2 12.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 7.1 PID AURORA B PATHWAY Aurora B signaling
0.2 7.0 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 9.0 PID LKB1 PATHWAY LKB1 signaling events
0.1 3.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 4.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 3.0 PID RHOA PATHWAY RhoA signaling pathway
0.1 4.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 1.6 PID ARF 3PATHWAY Arf1 pathway
0.1 2.0 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 0.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 3.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.9 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.6 PID E2F PATHWAY E2F transcription factor network
0.0 1.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 PID FOXO PATHWAY FoxO family signaling
0.0 1.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.8 PID P73PATHWAY p73 transcription factor network
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 18.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
1.5 25.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.9 21.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.8 13.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.8 19.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.8 13.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.7 13.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.7 12.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.6 24.0 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.6 2.4 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.5 19.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.5 10.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.5 10.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.5 7.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 8.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.4 7.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 15.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.4 52.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.3 17.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 8.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.3 6.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 7.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.3 7.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.3 6.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 6.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 2.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 28.9 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.3 6.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.3 5.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3 6.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 4.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 24.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 9.6 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.2 5.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.2 5.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 11.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 3.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 3.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 16.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 12.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 10.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 15.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.2 15.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 1.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 7.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 2.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 5.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 5.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 9.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 7.9 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 2.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 0.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 2.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 4.2 REACTOME TRANSLATION Genes involved in Translation
0.1 1.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 3.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 3.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 6.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 5.3 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1 2.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 2.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 2.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.1 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 0.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 2.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.5 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 2.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism