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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for EOMES

Z-value: 1.04

Motif logo

Transcription factors associated with EOMES

Gene Symbol Gene ID Gene Info
ENSG00000163508.8 eomesodermin

Activity profile of EOMES motif

Sorted Z-values of EOMES motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_55658252 24.21 ENST00000395425.2
discs, large (Drosophila) homolog-associated protein 5
chr9_+_91926103 23.75 ENST00000314355.6
CDC28 protein kinase regulatory subunit 2
chr14_-_55658323 20.83 ENST00000554067.1
ENST00000247191.2
discs, large (Drosophila) homolog-associated protein 5
chr7_-_96339132 19.10 ENST00000413065.1
split hand/foot malformation (ectrodactyly) type 1
chr6_+_34204642 18.64 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr1_-_167906277 16.99 ENST00000271373.4
mitochondrial pyruvate carrier 2
chr14_+_54863739 16.64 ENST00000541304.1
cyclin-dependent kinase inhibitor 3
chr1_+_87170577 16.48 ENST00000482504.1
SH3-domain GRB2-like endophilin B1
chr1_+_162531294 16.26 ENST00000367926.4
ENST00000271469.3
UDP-N-acteylglucosamine pyrophosphorylase 1
chr10_-_58120996 16.26 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZW10 interacting kinetochore protein
chr1_-_193029192 15.36 ENST00000417752.1
ENST00000367452.4
ubiquitin carboxyl-terminal hydrolase L5
chr11_-_57103327 14.30 ENST00000529002.1
ENST00000278412.2
structure specific recognition protein 1
chr11_+_64808675 13.99 ENST00000529996.1
SAC3 domain containing 1
chr2_-_161350305 13.89 ENST00000348849.3
RNA binding motif, single stranded interacting protein 1
chr7_-_99698338 13.59 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr19_+_35645817 13.36 ENST00000423817.3
FXYD domain containing ion transport regulator 5
chr3_-_167452262 12.88 ENST00000487947.2
programmed cell death 10
chr7_+_87505544 12.00 ENST00000265728.1
DBF4 homolog (S. cerevisiae)
chr11_-_66056596 11.64 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
Yip1 interacting factor homolog A (S. cerevisiae)
chr8_-_109260897 11.58 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
eukaryotic translation initiation factor 3, subunit E
chr12_+_54378923 11.31 ENST00000303460.4
homeobox C10
chr19_+_35645618 11.28 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD domain containing ion transport regulator 5
chr7_-_96339167 11.16 ENST00000444799.1
ENST00000417009.1
ENST00000248566.2
split hand/foot malformation (ectrodactyly) type 1
chr3_-_167452298 10.68 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
programmed cell death 10
chr3_-_182698381 10.48 ENST00000292782.4
DCN1, defective in cullin neddylation 1, domain containing 1
chr13_+_28195988 10.42 ENST00000399697.3
ENST00000399696.1
polymerase (RNA) I polypeptide D, 16kDa
chr22_+_40742512 10.40 ENST00000454266.2
ENST00000342312.6
adenylosuccinate lyase
chr11_-_102323489 10.40 ENST00000361236.3
transmembrane protein 123
chr19_+_16178317 10.36 ENST00000344824.6
ENST00000538887.1
tropomyosin 4
chr19_+_49496705 10.10 ENST00000595090.1
RuvB-like AAA ATPase 2
chr11_-_107729887 9.99 ENST00000525815.1
solute carrier family 35, member F2
chr7_-_93520259 9.91 ENST00000222543.5
tissue factor pathway inhibitor 2
chr3_-_131221790 9.85 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
mitochondrial ribosomal protein L3
chr5_+_32531893 9.82 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr1_+_43148625 9.62 ENST00000436427.1
Y box binding protein 1
chrX_+_21958814 9.61 ENST00000379404.1
ENST00000415881.2
spermine synthase
chr20_-_57617831 9.55 ENST00000371033.5
ENST00000355937.4
slowmo homolog 2 (Drosophila)
chrX_+_21958674 9.54 ENST00000404933.2
spermine synthase
chr11_+_64808368 9.45 ENST00000531072.1
ENST00000398846.1
SAC3 domain containing 1
chr1_+_43148059 9.29 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr22_+_40742497 9.29 ENST00000216194.7
adenylosuccinate lyase
chr2_+_201936707 9.27 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr18_-_47017956 9.18 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32 readthrough
ribosomal protein L17
chr13_+_28194873 8.80 ENST00000302979.3
polymerase (RNA) I polypeptide D, 16kDa
chr11_-_33757950 8.68 ENST00000533403.1
ENST00000528700.1
ENST00000527577.1
ENST00000395850.3
ENST00000351554.3
CD59 molecule, complement regulatory protein
chr1_+_19578033 8.65 ENST00000330263.4
mRNA turnover 4 homolog (S. cerevisiae)
chr2_+_201170770 8.58 ENST00000409988.3
ENST00000409385.1
spermatogenesis associated, serine-rich 2-like
chr4_-_183838596 8.54 ENST00000508994.1
ENST00000512766.1
dCMP deaminase
chr19_+_49496782 8.39 ENST00000601968.1
ENST00000596837.1
RuvB-like AAA ATPase 2
chr19_+_33865218 8.29 ENST00000585933.2
CCAAT/enhancer binding protein (C/EBP), gamma
chr11_+_34073269 7.99 ENST00000389645.3
cell cycle associated protein 1
chrX_-_114953669 7.95 ENST00000449327.1
Uncharacterized protein
chr2_+_201171242 7.91 ENST00000360760.5
spermatogenesis associated, serine-rich 2-like
chr11_+_65686728 7.88 ENST00000312515.2
ENST00000525501.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr8_-_124408652 7.88 ENST00000287394.5
ATPase family, AAA domain containing 2
chr1_-_245027833 7.85 ENST00000444376.2
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr11_+_35201826 7.81 ENST00000531873.1
CD44 molecule (Indian blood group)
chr7_+_16685756 7.71 ENST00000415365.1
ENST00000258761.3
ENST00000433922.2
ENST00000452975.2
ENST00000405202.1
basic leucine zipper and W2 domains 2
chr9_+_110045537 7.69 ENST00000358015.3
RAD23 homolog B (S. cerevisiae)
chr5_+_52083730 7.67 ENST00000282588.6
ENST00000274311.2
integrin, alpha 1
pelota homolog (Drosophila)
chr13_-_113862401 7.66 ENST00000375459.1
PCI domain containing 2
chr11_+_111896320 7.64 ENST00000531306.1
ENST00000537636.1
dihydrolipoamide S-acetyltransferase
chr6_-_131949200 7.57 ENST00000539158.1
ENST00000368058.1
mediator complex subunit 23
chr7_-_93519471 7.56 ENST00000451238.1
tissue factor pathway inhibitor 2
chr11_-_102323740 7.53 ENST00000398136.2
transmembrane protein 123
chr1_-_167906020 7.49 ENST00000458574.1
mitochondrial pyruvate carrier 2
chr3_-_167452614 7.42 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
programmed cell death 10
chr7_-_93520191 7.35 ENST00000545378.1
tissue factor pathway inhibitor 2
chr7_+_156931606 7.29 ENST00000348165.5
ubiquitin protein ligase E3C
chr8_-_101734308 7.26 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
poly(A) binding protein, cytoplasmic 1
chr1_-_31769656 7.24 ENST00000446633.2
small nuclear ribonucleoprotein 40kDa (U5)
chrX_+_118602363 7.17 ENST00000317881.8
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr4_+_17812525 7.12 ENST00000251496.2
non-SMC condensin I complex, subunit G
chr8_-_117778494 7.11 ENST00000276682.4
eukaryotic translation initiation factor 3, subunit H
chr16_+_30064444 7.05 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
aldolase A, fructose-bisphosphate
chr11_+_65686802 7.02 ENST00000376991.2
DR1-associated protein 1 (negative cofactor 2 alpha)
chr2_-_69664549 7.01 ENST00000450796.2
ENST00000484177.1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr11_+_34073757 6.92 ENST00000532820.1
cell cycle associated protein 1
chr8_-_90996837 6.92 ENST00000519426.1
ENST00000265433.3
nibrin
chr2_-_9770706 6.87 ENST00000381844.4
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
chr1_-_245027766 6.85 ENST00000283179.9
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr5_-_133968529 6.76 ENST00000402673.2
SAR1 homolog B (S. cerevisiae)
chr1_-_31769595 6.72 ENST00000263694.4
small nuclear ribonucleoprotein 40kDa (U5)
chr3_-_167452703 6.70 ENST00000497056.2
ENST00000473645.2
programmed cell death 10
chr8_-_103668114 6.68 ENST00000285407.6
Kruppel-like factor 10
chr11_+_112097069 6.56 ENST00000280362.3
ENST00000525803.1
6-pyruvoyltetrahydropterin synthase
chrX_+_150151752 6.45 ENST00000325307.7
high mobility group box 3
chr3_+_196466710 6.45 ENST00000327134.3
p21 protein (Cdc42/Rac)-activated kinase 2
chr13_+_29233218 6.41 ENST00000380842.4
proteasome maturation protein
chr11_+_73498898 6.39 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
mitochondrial ribosomal protein L48
chr16_-_67693846 6.34 ENST00000602850.1
adrenocortical dysplasia homolog (mouse)
chr6_-_131277510 6.33 ENST00000525193.1
ENST00000527659.1
erythrocyte membrane protein band 4.1-like 2
chr1_-_246729544 6.29 ENST00000544618.1
ENST00000366514.4
transcription factor B2, mitochondrial
chr7_+_94285637 6.26 ENST00000482108.1
ENST00000488574.1
paternally expressed 10
chr22_-_18257178 6.24 ENST00000342111.5
BH3 interacting domain death agonist
chr2_-_179315786 6.23 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
protein kinase, interferon-inducible double stranded RNA dependent activator
chr1_+_218458625 6.14 ENST00000366932.3
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr11_+_111896090 6.14 ENST00000393051.1
dihydrolipoamide S-acetyltransferase
chr3_-_123710893 6.13 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
rhophilin associated tail protein 1
chr2_+_201170596 6.04 ENST00000439084.1
ENST00000409718.1
spermatogenesis associated, serine-rich 2-like
chr1_-_244615425 6.03 ENST00000366535.3
adenylosuccinate synthase
chr10_+_75910960 6.02 ENST00000539909.1
ENST00000286621.2
adenosine kinase
chr22_+_38071615 6.00 ENST00000215909.5
lectin, galactoside-binding, soluble, 1
chr15_+_48623208 5.92 ENST00000559935.1
ENST00000559416.1
deoxyuridine triphosphatase
chr12_-_56709674 5.92 ENST00000551286.1
ENST00000549318.1
canopy FGF signaling regulator 2
Uncharacterized protein
chr4_+_169418195 5.91 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr2_-_179315453 5.87 ENST00000432031.2
protein kinase, interferon-inducible double stranded RNA dependent activator
chr17_+_33914460 5.82 ENST00000537622.2
adaptor-related protein complex 2, beta 1 subunit
chr2_-_69664586 5.81 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr2_-_179315490 5.73 ENST00000487082.1
protein kinase, interferon-inducible double stranded RNA dependent activator
chr17_-_61850894 5.67 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
coiled-coil domain containing 47
chr22_-_39096661 5.61 ENST00000216039.5
Josephin domain containing 1
chr11_-_62439012 5.56 ENST00000532208.1
ENST00000377954.2
ENST00000415855.2
ENST00000431002.2
ENST00000354588.3
chromosome 11 open reading frame 48
chr3_+_125687987 5.56 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
rhophilin associated tail protein 1B
chr3_-_127842612 5.52 ENST00000417360.1
ENST00000322623.5
RuvB-like AAA ATPase 1
chr2_+_201171372 5.52 ENST00000409140.3
spermatogenesis associated, serine-rich 2-like
chr15_-_90777277 5.49 ENST00000328649.6
calcium and integrin binding 1 (calmyrin)
chr16_+_30064411 5.46 ENST00000338110.5
aldolase A, fructose-bisphosphate
chr1_-_33283754 5.42 ENST00000373477.4
tyrosyl-tRNA synthetase
chr1_-_207095212 5.41 ENST00000420007.2
Fas apoptotic inhibitory molecule 3
chr9_+_115983808 5.40 ENST00000374210.6
ENST00000374212.4
solute carrier family 31 (copper transporter), member 1
chr18_-_47018869 5.38 ENST00000583036.1
ENST00000580261.1
ribosomal protein L17
chr13_-_31191642 5.38 ENST00000405805.1
high mobility group box 1
chr15_-_56285742 5.25 ENST00000435532.3
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr6_-_35888824 5.21 ENST00000361690.3
ENST00000512445.1
SRSF protein kinase 1
chr1_-_207095324 5.17 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr16_+_29817841 5.15 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chrX_+_131157322 5.14 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
Serine/threonine-protein kinase MST4
chrX_+_150151824 5.07 ENST00000455596.1
ENST00000448905.2
high mobility group box 3
chrX_+_131157290 5.07 ENST00000394334.2
Serine/threonine-protein kinase MST4
chr10_+_106014468 4.99 ENST00000369710.4
ENST00000369713.5
ENST00000445155.1
glutathione S-transferase omega 1
chr2_-_170430277 4.97 ENST00000438035.1
ENST00000453929.2
FAST kinase domains 1
chr3_-_125239010 4.95 ENST00000536067.1
ENST00000251775.4
sorting nexin 4
chrX_+_77359726 4.86 ENST00000442431.1
phosphoglycerate kinase 1
chr11_+_34073195 4.85 ENST00000341394.4
cell cycle associated protein 1
chr17_+_33914276 4.79 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr18_-_19284724 4.77 ENST00000580981.1
ENST00000289119.2
abhydrolase domain containing 3
chr15_+_48623600 4.75 ENST00000558813.1
ENST00000331200.3
ENST00000558472.1
deoxyuridine triphosphatase
chr8_-_90996459 4.69 ENST00000517337.1
ENST00000409330.1
nibrin
chr20_+_1099233 4.63 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr20_-_34252759 4.57 ENST00000414711.1
ENST00000416778.1
ENST00000397442.1
ENST00000440240.1
ENST00000412056.1
ENST00000352393.4
ENST00000458038.1
ENST00000420363.1
ENST00000434795.1
ENST00000437100.1
ENST00000414664.1
ENST00000359646.1
ENST00000424458.1
ENST00000374104.3
ENST00000374114.3
copine I
RNA binding motif protein 12
chr2_-_219134343 4.57 ENST00000447885.1
ENST00000420660.1
angio-associated, migratory cell protein
chr6_-_75953484 4.53 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr1_-_153949751 4.48 ENST00000428469.1
jumping translocation breakpoint
chr8_+_144099896 4.43 ENST00000292494.6
ENST00000429120.2
lymphocyte antigen 6 complex, locus E
chr17_-_1588101 4.32 ENST00000577001.1
ENST00000572621.1
ENST00000304992.6
pre-mRNA processing factor 8
chr6_-_109703634 4.32 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164 molecule, sialomucin
chr7_+_55177416 4.28 ENST00000450046.1
ENST00000454757.2
epidermal growth factor receptor
chr10_+_85899196 4.28 ENST00000372134.3
growth hormone inducible transmembrane protein
chr22_-_42486747 4.25 ENST00000602404.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
chr1_+_167906056 4.25 ENST00000367840.3
DDB1 and CUL4 associated factor 6
chr15_+_89182178 4.23 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr4_-_54930790 4.18 ENST00000263921.3
cysteine-rich hydrophobic domain 2
chr2_+_99953816 4.17 ENST00000289371.6
eukaryotic translation initiation factor 5B
chr8_-_117768023 4.15 ENST00000518949.1
ENST00000522453.1
ENST00000521861.1
ENST00000518995.1
eukaryotic translation initiation factor 3, subunit H
chr8_+_144099914 4.13 ENST00000521699.1
ENST00000520531.1
ENST00000520466.1
ENST00000521003.1
ENST00000522528.1
ENST00000522971.1
ENST00000519611.1
ENST00000521182.1
ENST00000519546.1
ENST00000523847.1
ENST00000522024.1
lymphocyte antigen 6 complex, locus E
chr15_-_85259294 4.08 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
SEC11 homolog A (S. cerevisiae)
chr19_+_19303008 4.08 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
regulatory factor X-associated ankyrin-containing protein
chr11_+_63706444 4.03 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr19_+_13261216 4.00 ENST00000587885.1
ENST00000292433.3
immediate early response 2
chr14_-_24682652 3.99 ENST00000556387.1
ENST00000530611.1
ENST00000609024.1
ENST00000530996.1
transmembrane 9 superfamily member 1
Transmembrane 9 superfamily member 1
charged multivesicular body protein 4A
chr1_+_186344883 3.98 ENST00000367470.3
chromosome 1 open reading frame 27
chr1_+_186344945 3.96 ENST00000419367.3
ENST00000287859.6
chromosome 1 open reading frame 27
chrX_-_102757802 3.94 ENST00000372633.1
RAB40A, member RAS oncogene family
chr19_-_2427536 3.91 ENST00000591871.1
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr1_-_205744205 3.89 ENST00000446390.2
RAB7, member RAS oncogene family-like 1
chr9_-_117853297 3.83 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
tenascin C
chr3_+_133292574 3.79 ENST00000264993.3
CDV3 homolog (mouse)
chr6_-_74233480 3.77 ENST00000455918.1
eukaryotic translation elongation factor 1 alpha 1
chr14_-_51135036 3.77 ENST00000324679.4
salvador homolog 1 (Drosophila)
chr16_+_202686 3.73 ENST00000252951.2
hemoglobin, zeta
chr10_-_94333784 3.72 ENST00000265986.6
insulin-degrading enzyme
chr11_+_69455855 3.72 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr17_-_15587602 3.68 ENST00000416464.2
ENST00000578237.1
ENST00000581200.1
tripartite motif containing 16
chr19_+_34856141 3.66 ENST00000586425.1
glucose-6-phosphate isomerase
chr4_-_144940477 3.53 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
glycophorin B (MNS blood group)
chr6_-_111927062 3.52 ENST00000359831.4
TRAF3 interacting protein 2
chr13_+_73302047 3.52 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
bora, aurora kinase A activator
chr19_+_9938562 3.52 ENST00000586895.1
ENST00000358666.3
ENST00000590068.1
ENST00000593087.1
ubiquitin-like 5
chr1_-_184943610 3.48 ENST00000367511.3
family with sequence similarity 129, member A
chr9_+_140172200 3.47 ENST00000357503.2
torsin family 4, member A
chr15_-_85259330 3.46 ENST00000560266.1
SEC11 homolog A (S. cerevisiae)
chr15_-_85259384 3.45 ENST00000455959.3
SEC11 homolog A (S. cerevisiae)
chr2_-_65357225 3.44 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A, member RAS oncogene family
chr1_-_153950098 3.38 ENST00000356648.1
jumping translocation breakpoint
chr5_+_96212185 3.37 ENST00000379904.4
endoplasmic reticulum aminopeptidase 2
chr2_-_54197915 3.31 ENST00000404125.1
proteasome (prosome, macropain) activator subunit 4
chr17_-_77813186 3.29 ENST00000448310.1
ENST00000269397.4
chromobox homolog 4
chr19_-_3061397 3.22 ENST00000586839.1
amino-terminal enhancer of split
chr1_-_205744574 3.21 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7, member RAS oncogene family-like 1
chr7_+_129710350 3.21 ENST00000335420.5
ENST00000463413.1
kelch domain containing 10
chr6_-_109702885 3.16 ENST00000504373.1
CD164 molecule, sialomucin
chr20_-_34252847 3.15 ENST00000317619.3
ENST00000397446.1
ENST00000397445.1
ENST00000397443.1
ENST00000430570.1
ENST00000439806.2
ENST00000437340.1
ENST00000435161.1
ENST00000431148.1
copine I
RNA binding motif protein 12
chr9_+_37486005 3.14 ENST00000377792.3
polymerase (RNA) I polypeptide E, 53kDa
chr4_-_151936865 3.13 ENST00000535741.1
LPS-responsive vesicle trafficking, beach and anchor containing
chr1_-_153950116 3.09 ENST00000368589.1
jumping translocation breakpoint
chr19_+_55897699 3.08 ENST00000558131.1
ENST00000558752.1
ENST00000458349.2
ribosomal protein L28
chr19_-_49496557 3.08 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
glycogen synthase 1 (muscle)
chr17_+_48133459 3.07 ENST00000320031.8
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr3_+_111805182 3.01 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
chromosome 3 open reading frame 52

Network of associatons between targets according to the STRING database.

First level regulatory network of EOMES

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 25.7 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
8.2 24.6 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
7.5 37.7 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
7.5 45.0 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
6.4 19.2 GO:0006597 spermine biosynthetic process(GO:0006597)
6.1 24.5 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
4.8 33.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
4.7 18.6 GO:0090402 oncogene-induced cell senescence(GO:0090402)
4.6 18.5 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
4.1 16.5 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
3.6 10.7 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
3.1 9.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.1 9.2 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
2.9 11.6 GO:0031860 telomeric 3' overhang formation(GO:0031860)
2.5 5.0 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
2.2 8.7 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
2.1 8.5 GO:0006226 dUMP biosynthetic process(GO:0006226)
2.1 10.6 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
2.0 6.0 GO:0044209 AMP salvage(GO:0044209)
1.8 5.5 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
1.6 6.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
1.6 4.7 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
1.6 14.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.5 7.7 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.5 6.0 GO:0002317 plasma cell differentiation(GO:0002317)
1.4 4.3 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
1.4 17.8 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
1.3 5.4 GO:0002424 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
1.3 5.3 GO:0044111 development involved in symbiotic interaction(GO:0044111)
1.3 11.6 GO:1902416 positive regulation of mRNA binding(GO:1902416)
1.3 7.7 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.3 3.8 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
1.3 11.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
1.3 16.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
1.2 3.7 GO:1901143 insulin catabolic process(GO:1901143)
1.2 3.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
1.2 7.2 GO:1901029 adenine transport(GO:0015853) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
1.1 4.5 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
1.1 17.9 GO:0045793 positive regulation of cell size(GO:0045793)
1.1 5.3 GO:0072719 cellular response to cisplatin(GO:0072719)
1.0 8.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
1.0 4.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
1.0 2.1 GO:2000078 positive regulation of type B pancreatic cell development(GO:2000078)
1.0 7.8 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.0 15.4 GO:0021670 lateral ventricle development(GO:0021670)
0.9 8.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.8 5.0 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.8 7.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.8 4.0 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.8 2.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.7 2.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.7 6.6 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.7 2.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.7 7.0 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.7 10.5 GO:0045116 protein neddylation(GO:0045116)
0.7 2.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.7 2.7 GO:0072183 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.7 7.4 GO:0006983 ER overload response(GO:0006983)
0.7 2.0 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.7 11.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.7 5.9 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.6 5.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.6 7.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.6 19.8 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.6 1.9 GO:0060535 trachea cartilage morphogenesis(GO:0060535) renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.6 13.8 GO:0006465 signal peptide processing(GO:0006465)
0.6 2.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.6 27.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.6 18.2 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.6 12.8 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.6 1.7 GO:0006404 RNA import into nucleus(GO:0006404)
0.5 1.6 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.5 3.1 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.5 3.6 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.5 3.0 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.5 19.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.5 2.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.5 1.4 GO:0040031 snRNA modification(GO:0040031)
0.5 1.9 GO:0098838 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.5 1.9 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.5 1.8 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.5 6.4 GO:0043248 proteasome assembly(GO:0043248)
0.5 6.3 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.4 7.9 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.4 1.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.4 3.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.4 3.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.4 1.6 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.4 5.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4 8.7 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.3 1.4 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.3 2.8 GO:0044351 macropinocytosis(GO:0044351)
0.3 2.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.3 2.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3 5.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 7.1 GO:0003334 keratinocyte development(GO:0003334)
0.3 1.5 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.3 0.9 GO:0019858 cytosine metabolic process(GO:0019858)
0.3 3.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 3.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 3.7 GO:0015671 oxygen transport(GO:0015671)
0.3 0.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.3 22.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.3 16.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.3 6.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 10.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.3 1.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.3 2.3 GO:0034214 protein hexamerization(GO:0034214)
0.3 2.8 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 15.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 4.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.2 3.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 1.9 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 3.8 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 3.8 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.2 2.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2 11.5 GO:0032392 DNA geometric change(GO:0032392)
0.2 1.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.2 1.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 2.5 GO:0051451 myoblast migration(GO:0051451)
0.2 16.2 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.2 2.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 1.8 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2 2.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 1.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 3.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 0.8 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 5.2 GO:0031639 plasminogen activation(GO:0031639)
0.2 5.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 4.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 1.6 GO:0070828 heterochromatin organization(GO:0070828)
0.2 0.5 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.2 15.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.2 19.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 0.9 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 2.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 3.5 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 3.5 GO:0001783 B cell apoptotic process(GO:0001783)
0.1 1.5 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.1 12.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 1.4 GO:0010225 response to UV-C(GO:0010225)
0.1 2.5 GO:0036260 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.1 7.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 2.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 3.1 GO:0097062 dendritic spine maintenance(GO:0097062) renal filtration(GO:0097205)
0.1 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 1.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 2.5 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 1.1 GO:0014041 regulation of neuron maturation(GO:0014041)
0.1 0.8 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.8 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 1.8 GO:0006020 inositol metabolic process(GO:0006020)
0.1 2.8 GO:0030488 tRNA methylation(GO:0030488)
0.1 6.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 11.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 4.8 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.3 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 0.6 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 11.8 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.1 1.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 8.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 4.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 1.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 6.9 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.4 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 6.2 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1 3.9 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 0.3 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.1 0.6 GO:0016255 polyol transport(GO:0015791) attachment of GPI anchor to protein(GO:0016255)
0.1 2.5 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 1.1 GO:0031053 primary miRNA processing(GO:0031053)
0.1 1.0 GO:0070986 left/right axis specification(GO:0070986)
0.1 3.7 GO:0006119 oxidative phosphorylation(GO:0006119)
0.1 0.4 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 1.8 GO:0002360 T cell lineage commitment(GO:0002360)
0.1 1.8 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 0.7 GO:0070673 response to interleukin-18(GO:0070673)
0.1 0.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 3.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.8 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.3 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.6 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 4.7 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 3.2 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.1 0.9 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.8 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.0 2.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.0 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 2.6 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.8 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.3 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 1.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0051182 coenzyme transport(GO:0051182)
0.0 1.2 GO:0006270 DNA replication initiation(GO:0006270)
0.0 3.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 1.8 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:1905066 arterial endothelial cell fate commitment(GO:0060844) canonical Wnt signaling pathway involved in heart development(GO:0061316) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 1.1 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 1.7 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.8 GO:0003016 respiratory system process(GO:0003016)
0.0 2.4 GO:0045333 cellular respiration(GO:0045333)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 1.2 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 5.7 GO:0006260 DNA replication(GO:0006260)
0.0 0.2 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 1.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 11.3 GO:0051301 cell division(GO:0051301)
0.0 0.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0032962 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.2 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.5 GO:0006915 apoptotic process(GO:0006915)
0.0 0.1 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 0.3 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.8 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
3.4 33.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
3.1 3.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
2.6 45.0 GO:0031616 spindle pole centrosome(GO:0031616)
2.6 7.7 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
2.6 25.5 GO:0097255 R2TP complex(GO:0097255)
2.0 13.8 GO:0005787 signal peptidase complex(GO:0005787)
1.7 18.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.7 11.6 GO:0030870 Mre11 complex(GO:0030870)
1.4 7.2 GO:0071817 MMXD complex(GO:0071817)
1.4 4.3 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
1.3 23.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
1.3 11.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
1.3 11.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.1 9.2 GO:0070187 telosome(GO:0070187)
1.1 7.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.1 5.4 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
1.0 16.8 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.0 13.6 GO:0042555 MCM complex(GO:0042555)
0.9 12.3 GO:0070578 RISC-loading complex(GO:0070578)
0.9 24.5 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.8 2.4 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.7 11.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.7 7.1 GO:0000796 condensin complex(GO:0000796)
0.7 2.1 GO:0044305 calyx of Held(GO:0044305)
0.6 14.0 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.6 2.4 GO:0032279 asymmetric synapse(GO:0032279)
0.6 3.0 GO:0089701 U2AF(GO:0089701)
0.6 10.6 GO:0030122 AP-2 adaptor complex(GO:0030122) endolysosome membrane(GO:0036020)
0.5 10.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.5 8.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 20.5 GO:0000421 autophagosome membrane(GO:0000421)
0.5 1.5 GO:0033565 ESCRT-0 complex(GO:0033565)
0.5 27.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.5 3.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.5 1.8 GO:0032044 DSIF complex(GO:0032044)
0.5 6.3 GO:0008091 spectrin(GO:0008091)
0.5 7.7 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.4 3.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.4 27.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 13.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.4 3.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 16.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4 3.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 13.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.4 2.2 GO:0001740 Barr body(GO:0001740)
0.3 3.8 GO:0005614 interstitial matrix(GO:0005614)
0.3 2.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 15.1 GO:0031430 M band(GO:0031430)
0.3 2.3 GO:0032059 bleb(GO:0032059)
0.3 5.5 GO:0032433 filopodium tip(GO:0032433)
0.3 6.2 GO:0030056 hemidesmosome(GO:0030056)
0.3 3.7 GO:0005833 hemoglobin complex(GO:0005833)
0.3 1.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 2.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.3 3.6 GO:0036038 MKS complex(GO:0036038)
0.3 1.8 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.2 3.7 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.2 15.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 6.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 6.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 5.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 20.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 4.6 GO:0005839 proteasome core complex(GO:0005839)
0.2 10.1 GO:0015030 Cajal body(GO:0015030)
0.2 6.5 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.2 5.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 7.3 GO:0000502 proteasome complex(GO:0000502)
0.1 7.1 GO:0002102 podosome(GO:0002102)
0.1 15.1 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.1 4.8 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 1.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.1 GO:0031941 filamentous actin(GO:0031941)
0.1 7.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 1.8 GO:0000786 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.1 1.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 2.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 8.1 GO:0005694 chromosome(GO:0005694)
0.1 4.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 30.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 1.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 2.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 3.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.5 GO:0001739 sex chromatin(GO:0001739)
0.1 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 5.4 GO:0000793 condensed chromosome(GO:0000793)
0.1 4.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 5.7 GO:0001650 fibrillar center(GO:0001650)
0.0 13.7 GO:0005819 spindle(GO:0005819)
0.0 2.1 GO:0030175 filopodium(GO:0030175)
0.0 3.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 2.0 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 3.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 6.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.9 GO:0043209 myelin sheath(GO:0043209)
0.0 1.2 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 5.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 3.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 10.6 GO:0005730 nucleolus(GO:0005730)
0.0 8.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.8 GO:0016418 S-acetyltransferase activity(GO:0016418)
4.0 24.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
3.6 10.7 GO:0004170 dUTP diphosphatase activity(GO:0004170)
3.4 23.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
3.1 9.3 GO:0008859 exoribonuclease II activity(GO:0008859)
3.1 24.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
3.0 24.4 GO:0016842 amidine-lyase activity(GO:0016842)
2.2 6.6 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
2.1 8.5 GO:0004132 dCMP deaminase activity(GO:0004132)
2.0 6.0 GO:0048030 disaccharide binding(GO:0048030)
2.0 17.8 GO:0070883 pre-miRNA binding(GO:0070883)
1.8 10.9 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
1.8 7.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
1.7 5.0 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
1.6 4.9 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
1.5 7.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
1.5 16.3 GO:0070569 uridylyltransferase activity(GO:0070569)
1.4 4.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
1.3 18.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
1.3 23.7 GO:0001054 RNA polymerase I activity(GO:0001054)
1.3 2.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.3 6.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.2 3.7 GO:0032089 NACHT domain binding(GO:0032089)
1.2 3.7 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
1.1 23.3 GO:0070628 proteasome binding(GO:0070628)
1.1 11.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.0 5.0 GO:1990460 leptin receptor binding(GO:1990460)
1.0 4.8 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.9 4.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.8 4.0 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.8 2.3 GO:0070546 phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.8 5.3 GO:0050815 phosphoserine binding(GO:0050815)
0.7 2.9 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.7 2.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.7 2.0 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.6 25.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.6 19.8 GO:0008301 DNA binding, bending(GO:0008301)
0.6 6.3 GO:0042731 PH domain binding(GO:0042731)
0.6 2.5 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.6 3.0 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.6 2.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.6 10.5 GO:0097602 cullin family protein binding(GO:0097602)
0.5 1.6 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.5 5.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.5 5.4 GO:0045545 syndecan binding(GO:0045545)
0.5 6.0 GO:0042301 phosphate ion binding(GO:0042301)
0.5 2.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.5 1.9 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.5 9.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.5 10.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.5 1.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.5 1.9 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.5 3.7 GO:0043559 insulin binding(GO:0043559)
0.4 69.4 GO:0047485 protein N-terminus binding(GO:0047485)
0.4 50.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.4 2.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.4 9.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.4 11.9 GO:0070034 telomerase RNA binding(GO:0070034)
0.4 3.6 GO:0008158 hedgehog receptor activity(GO:0008158)
0.4 2.4 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.4 21.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.4 1.8 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.3 10.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 6.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 2.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3 12.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.3 7.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 3.5 GO:0031386 protein tag(GO:0031386)
0.3 15.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 3.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 1.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.3 2.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.3 24.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 2.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3 3.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.3 8.7 GO:0001848 complement binding(GO:0001848)
0.3 3.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 7.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 4.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 4.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.2 6.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 2.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 5.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 1.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.2 1.5 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 3.7 GO:0019206 nucleoside kinase activity(GO:0019206)
0.2 7.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 2.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 9.2 GO:0000049 tRNA binding(GO:0000049)
0.2 15.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 2.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.2 9.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 0.8 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.2 6.2 GO:0005123 death receptor binding(GO:0005123)
0.2 5.1 GO:0030506 ankyrin binding(GO:0030506)
0.2 0.5 GO:0003883 CTP synthase activity(GO:0003883)
0.2 3.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 2.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 3.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 12.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 3.1 GO:0001968 fibronectin binding(GO:0001968)
0.1 4.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 29.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 23.2 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 10.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.2 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 2.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 4.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 2.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.7 GO:0043495 protein anchor(GO:0043495)
0.1 1.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 5.0 GO:0003682 chromatin binding(GO:0003682)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 2.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 1.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 1.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 1.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.9