GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
ETV3 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000117036.7	ETS variant transcription factor 3

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ETV3	hg19_v2_chr1_-_157108266_157108347	0.47	1.2e-13	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr11_-_61129335 Show fit	66.66	ENST00000545361.1 ENST00000539128.1 ENST00000546151.1 ENST00000447532.2	CYB561A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome b561 family, member A3
chr18_-_72265035 Show fit	64.11	ENST00000585279.1 ENST00000580048.1	LINC00909 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 909
chr6_-_33239712 Show fit	52.61	ENST00000436044.2	VPS52 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuolar protein sorting 52 homolog (S. cerevisiae)
chr20_-_48532019 Show fit	43.81	ENST00000289431.5	SPATA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spermatogenesis associated 2
chr1_+_10003486 Show fit	43.57	ENST00000403197.1 ENST00000377205.1	NMNAT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nicotinamide nucleotide adenylyltransferase 1
chr5_-_130970723 Show fit	43.45	ENST00000308008.6 ENST00000296859.6 ENST00000507093.1 ENST00000510071.1 ENST00000509018.1 ENST00000307984.5	RAPGEF6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rap guanine nucleotide exchange factor (GEF) 6
chr3_+_57541975 Show fit	41.89	ENST00000487257.1 ENST00000311180.8	PDE12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphodiesterase 12
chr4_+_76439665 Show fit	37.50	ENST00000508105.1 ENST00000311638.3 ENST00000380837.3 ENST00000507556.1 ENST00000504190.1 ENST00000507885.1 ENST00000502620.1 ENST00000514480.1	THAP6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	THAP domain containing 6
chr3_+_15468862 Show fit	36.04	ENST00000396842.2	EAF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ELL associated factor 1
chr3_-_15469006 Show fit	36.03	ENST00000443029.1 ENST00000383790.3 ENST00000383789.5	METTL6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	methyltransferase like 6
chr19_+_58095501 Show fit	33.73	ENST00000536878.2 ENST00000597850.1 ENST00000597219.1 ENST00000598689.1 ENST00000599456.1 ENST00000307468.4	ZIK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein interacting with K protein 1
chr5_+_80597419 Show fit	32.12	ENST00000254037.2 ENST00000407610.3 ENST00000380199.5	ZCCHC9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger, CCHC domain containing 9
chr3_+_108308513 Show fit	31.16	ENST00000361582.3	DZIP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DAZ interacting zinc finger protein 3
chrX_+_55478538 Show fit	30.78	ENST00000342972.1	MAGEH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family H, 1
chr2_-_99224915 Show fit	28.83	ENST00000328709.3 ENST00000409997.1	COA5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome c oxidase assembly factor 5
chr6_-_33239612 Show fit	28.46	ENST00000482399.1 ENST00000445902.2	VPS52 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuolar protein sorting 52 homolog (S. cerevisiae)
chr1_+_169337172 Show fit	28.30	ENST00000367807.3 ENST00000367808.3 ENST00000329281.2 ENST00000420531.1	BLZF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	basic leucine zipper nuclear factor 1
chr5_-_132202329 Show fit	27.68	ENST00000378673.2	GDF9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	growth differentiation factor 9
chr1_+_156698234 Show fit	26.87	ENST00000368218.4 ENST00000368216.4	RRNAD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal RNA adenine dimethylase domain containing 1
chr15_+_90808919 Show fit	26.15	ENST00000379095.3	NGRN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neugrin, neurite outgrowth associated
chr22_-_38245304 Show fit	26.12	ENST00000609454.1	ANKRD54 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin repeat domain 54
chr14_+_69865401 Show fit	25.63	ENST00000556605.1 ENST00000336643.5 ENST00000031146.4	SLC39A9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 39, member 9
chr11_+_71791849 Show fit	25.51	ENST00000423494.2 ENST00000539587.1 ENST00000538478.1 ENST00000324866.7 ENST00000439209.1	LRTOMT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich transmembrane and O-methyltransferase domain containing
chr19_+_56186606 Show fit	25.13	ENST00000085079.7	EPN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	epsin 1
chr9_+_37753795 Show fit	25.09	ENST00000377753.2 ENST00000537911.1 ENST00000377754.2 ENST00000297994.3	TRMT10B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tRNA methyltransferase 10 homolog B (S. cerevisiae)
chr15_+_71184931 Show fit	25.09	ENST00000560369.1 ENST00000260382.5	LRRC49 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich repeat containing 49
chr1_+_11866270 Show fit	24.82	ENST00000376497.3 ENST00000376487.3 ENST00000376496.3	CLCN6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chloride channel, voltage-sensitive 6
chr12_-_6798616 Show fit	24.18	ENST00000355772.4 ENST00000417772.3 ENST00000396801.3 ENST00000396799.2	ZNF384 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 384
chr1_+_156698708 Show fit	23.67	ENST00000519086.1	RRNAD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal RNA adenine dimethylase domain containing 1
chr11_+_71791693 Show fit	22.90	ENST00000289488.2 ENST00000447974.1	LRTOMT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich transmembrane and O-methyltransferase domain containing
chr17_+_27055798 Show fit	22.47	ENST00000268766.6	NEK8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NIMA-related kinase 8
chr12_+_132195617 Show fit	22.22	ENST00000261674.4 ENST00000535236.1 ENST00000541286.1	SFSWAP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	splicing factor, suppressor of white-apricot homolog (Drosophila)
chr9_-_86571628 Show fit	21.50	ENST00000376344.3	C9orf64 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 9 open reading frame 64
chr1_+_204485503 Show fit	21.45	ENST00000367182.3 ENST00000507825.2	MDM4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Mdm4 p53 binding protein homolog (mouse)
chr2_+_32502952 Show fit	21.43	ENST00000238831.4	YIPF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Yip1 domain family, member 4
chr16_+_2098003 Show fit	21.25	ENST00000439673.2 ENST00000350773.4	TSC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tuberous sclerosis 2
chr1_-_11866034 Show fit	21.12	ENST00000376590.3	MTHFR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	methylenetetrahydrofolate reductase (NAD(P)H)
chr8_-_56685859 Show fit	20.93	ENST00000523423.1 ENST00000523073.1 ENST00000519784.1 ENST00000434581.2 ENST00000519780.1 ENST00000521229.1 ENST00000522576.1 ENST00000523180.1 ENST00000522090.1	TMEM68 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 68
chr16_+_23652773 Show fit	20.87	ENST00000563998.1 ENST00000568589.1 ENST00000568272.1	DCTN5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dynactin 5 (p25)
chr12_+_108908962 Show fit	20.80	ENST00000552695.1 ENST00000552758.1 ENST00000361549.2	FICD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FIC domain containing
chrX_+_70586140 Show fit	20.65	ENST00000276072.3	TAF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr20_-_34638841 Show fit	20.43	ENST00000565493.1	LINC00657 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 657
chrX_+_47092314 Show fit	20.33	ENST00000218348.3	USP11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin specific peptidase 11
chr16_+_2097970 Show fit	20.19	ENST00000382538.6 ENST00000401874.2 ENST00000353929.4	TSC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tuberous sclerosis 2
chr1_+_11866207 Show fit	19.98	ENST00000312413.6 ENST00000346436.6	CLCN6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chloride channel, voltage-sensitive 6
chr1_-_11865982 Show fit	19.95	ENST00000418034.1	MTHFR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	methylenetetrahydrofolate reductase (NAD(P)H)
chr12_-_6798410 Show fit	19.89	ENST00000361959.3 ENST00000436774.2 ENST00000544482.1	ZNF384 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 384
chr19_+_56186557 Show fit	19.76	ENST00000270460.6	EPN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	epsin 1
chr8_-_56685966 Show fit	19.50	ENST00000334667.2	TMEM68 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 68
chr16_-_4466622 Show fit	19.10	ENST00000570645.1 ENST00000574025.1 ENST00000572898.1 ENST00000537233.2 ENST00000571059.1 ENST00000251166.4	CORO7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	coronin 7
chr5_-_74062930 Show fit	19.09	ENST00000509430.1 ENST00000345239.2 ENST00000427854.2 ENST00000506778.1	GFM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G elongation factor, mitochondrial 2
chr2_+_231729615 Show fit	19.01	ENST00000326427.6 ENST00000335005.6 ENST00000326407.6	ITM2C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integral membrane protein 2C
chr2_-_44588624 Show fit	19.00	ENST00000438314.1 ENST00000409936.1	PREPL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prolyl endopeptidase-like
chr12_-_6798523 Show fit	18.94	ENST00000319770.3	ZNF384 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 384
chr11_+_46722368 Show fit	18.90	ENST00000311764.2	ZNF408 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 408
chr17_-_18218237 Show fit	18.43	ENST00000542570.1	TOP3A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	topoisomerase (DNA) III alpha
chr14_-_81687575 Show fit	18.02	ENST00000434192.2	GTF2A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	general transcription factor IIA, 1, 19/37kDa
chr19_-_56632592 Show fit	17.95	ENST00000587279.1 ENST00000270459.3	ZNF787 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 787
chr18_-_47807829 Show fit	17.72	ENST00000585672.1 ENST00000457839.2 ENST00000353909.3 ENST00000339998.6 ENST00000398493.1	MBD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	methyl-CpG binding domain protein 1
chr15_+_74833518 Show fit	17.67	ENST00000346246.5	ARID3B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	AT rich interactive domain 3B (BRIGHT-like)
chr2_+_175260451 Show fit	17.63	ENST00000458563.1 ENST00000409673.3 ENST00000272732.6 ENST00000435964.1	SCRN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	secernin 3
chr11_-_64885111 Show fit	17.45	ENST00000528598.1 ENST00000310597.4	ZNHIT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger, HIT-type containing 2
chr2_-_44588694 Show fit	17.42	ENST00000409957.1	PREPL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prolyl endopeptidase-like
chr17_-_56595196 Show fit	17.39	ENST00000579921.1 ENST00000579925.1 ENST00000323456.5	MTMR4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myotubularin related protein 4
chr2_+_118846008 Show fit	17.14	ENST00000245787.4	INSIG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin induced gene 2
chr12_-_123215306 Show fit	17.08	ENST00000356987.2 ENST00000436083.2	HCAR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxycarboxylic acid receptor 1
chrX_+_70586082 Show fit	17.08	ENST00000373790.4 ENST00000449580.1 ENST00000423759.1	TAF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr19_+_50380682 Show fit	16.74	ENST00000221543.5	TBC1D17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TBC1 domain family, member 17
chr8_+_146052849 Show fit	16.68	ENST00000532777.1 ENST00000325241.6 ENST00000446747.2 ENST00000525266.1 ENST00000544249.1 ENST00000325217.5 ENST00000533314.1 ENST00000527218.1 ENST00000529819.1 ENST00000528372.1	ZNF7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 7
chr15_+_71185148 Show fit	16.65	ENST00000443425.2 ENST00000560755.1	LRRC49 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich repeat containing 49
chr2_-_175351744 Show fit	16.61	ENST00000295500.4 ENST00000392552.2 ENST00000392551.2	GPR155 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor 155
chr2_+_25016282 Show fit	16.61	ENST00000260662.1	CENPO Links Ensembl NCBI GeneCards UniProt NextProt Show fit	centromere protein O
chr17_-_37844267 Show fit	16.55	ENST00000579146.1 ENST00000378011.4 ENST00000429199.2 ENST00000300658.4	PGAP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	post-GPI attachment to proteins 3
chr5_-_139944196 Show fit	16.52	ENST00000357560.4	APBB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	amyloid beta (A4) precursor protein-binding, family B, member 3
chr2_-_44588679 Show fit	16.46	ENST00000409411.1	PREPL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prolyl endopeptidase-like
chr22_+_41865109 Show fit	16.39	ENST00000216254.4 ENST00000396512.3	ACO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aconitase 2, mitochondrial
chr8_+_95565947 Show fit	16.37	ENST00000523011.1	RP11-267M23.4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-267M23.4
chr19_-_16653226 Show fit	16.32	ENST00000198939.6	CHERP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium homeostasis endoplasmic reticulum protein
chr7_-_44530479 Show fit	16.30	ENST00000355451.7	NUDCD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NudC domain containing 3
chr13_-_46626847 Show fit	16.14	ENST00000242848.4 ENST00000282007.3	ZC3H13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger CCCH-type containing 13
chr19_+_50380917 Show fit	16.00	ENST00000535102.2	TBC1D17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TBC1 domain family, member 17
chr16_+_19535235 Show fit	15.88	ENST00000565376.2 ENST00000396208.2	CCP110 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	centriolar coiled coil protein 110kDa
chr10_+_127408110 Show fit	15.88	ENST00000356792.4	C10orf137 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	erythroid differentiation regulatory factor 1
chr16_-_89556942 Show fit	15.86	ENST00000301030.4	ANKRD11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin repeat domain 11
chr1_-_160001737 Show fit	15.85	ENST00000368090.2	PIGM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol glycan anchor biosynthesis, class M
chr19_+_47759716 Show fit	15.82	ENST00000221922.6	CCDC9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 9
chr11_+_61891445 Show fit	15.81	ENST00000394818.3 ENST00000533896.1 ENST00000278849.4	INCENP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	inner centromere protein antigens 135/155kDa
chr19_+_50381308 Show fit	15.80	ENST00000599049.2	TBC1D17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TBC1 domain family, member 17
chr3_-_28390581 Show fit	15.65	ENST00000479665.1	AZI2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	5-azacytidine induced 2
chr2_+_25015968 Show fit	15.64	ENST00000380834.2 ENST00000473706.1	CENPO Links Ensembl NCBI GeneCards UniProt NextProt Show fit	centromere protein O
chr17_+_4843654 Show fit	15.57	ENST00000575111.1	RNF167 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger protein 167
chr1_+_22351977 Show fit	15.47	ENST00000420503.1 ENST00000416769.1 ENST00000404210.2	LINC00339 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 339
chr1_+_168148273 Show fit	15.43	ENST00000367830.3	TIPRL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr22_+_38004832 Show fit	15.39	ENST00000405147.3 ENST00000429218.1 ENST00000325180.8 ENST00000337437.4	GGA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr3_-_101232019 Show fit	15.37	ENST00000394095.2 ENST00000394091.1 ENST00000394094.2 ENST00000358203.3 ENST00000348610.3 ENST00000314261.7	SENP7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SUMO1/sentrin specific peptidase 7
chr19_-_55690758 Show fit	15.25	ENST00000590851.1	SYT5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptotagmin V
chr18_-_47813940 Show fit	15.16	ENST00000586837.1 ENST00000412036.2 ENST00000589940.1	CXXC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CXXC finger protein 1
chr15_-_72978490 Show fit	14.89	ENST00000311755.3	HIGD2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	HIG1 hypoxia inducible domain family, member 2B
chr2_-_44588893 Show fit	14.78	ENST00000409272.1 ENST00000410081.1 ENST00000541738.1	PREPL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prolyl endopeptidase-like
chr2_+_113342163 Show fit	14.73	ENST00000409719.1	CHCHD5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil-helix-coiled-coil-helix domain containing 5
chr19_+_18263928 Show fit	14.66	ENST00000222254.8	PIK3R2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoinositide-3-kinase, regulatory subunit 2 (beta)
chr7_-_99149715 Show fit	14.64	ENST00000449309.1	FAM200A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 200, member A
chr19_-_16653325 Show fit	14.59	ENST00000546361.2	CHERP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium homeostasis endoplasmic reticulum protein
chr10_-_50747064 Show fit	14.59	ENST00000355832.5 ENST00000603152.1 ENST00000447839.2	ERCC6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit PGBD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit ERCC6-PGBD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	excision repair cross-complementing rodent repair deficiency, complementation group 6 piggyBac transposable element derived 3 ERCC6-PGBD3 readthrough
chr17_-_617949 Show fit	14.57	ENST00000401468.3 ENST00000574029.1 ENST00000291074.5 ENST00000571805.1 ENST00000437048.2 ENST00000446250.2	VPS53 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuolar protein sorting 53 homolog (S. cerevisiae)
chr1_+_28099683 Show fit	14.33	ENST00000373943.4	STX12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	syntaxin 12
chr22_+_30752606 Show fit	14.22	ENST00000399824.2 ENST00000405659.1 ENST00000338306.3	CCDC157 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 157
chr17_-_29641084 Show fit	14.22	ENST00000544462.1	EVI2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ecotropic viral integration site 2B
chr18_+_5238549 Show fit	14.17	ENST00000580684.1	LINC00667 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 667
chr20_+_43595115 Show fit	14.09	ENST00000372806.3 ENST00000396731.4 ENST00000372801.1 ENST00000499879.2	STK4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/threonine kinase 4
chr9_-_95432536 Show fit	13.99	ENST00000287996.3	IPPK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr17_+_10600894 Show fit	13.89	ENST00000379774.4	ADPRM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
chr3_-_137893721 Show fit	13.89	ENST00000505015.2 ENST00000260803.4	DBR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	debranching RNA lariats 1
chr11_-_62389449 Show fit	13.87	ENST00000534026.1	B3GAT3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr17_+_4843413 Show fit	13.87	ENST00000572430.1 ENST00000262482.6	RNF167 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger protein 167
chr11_-_46722117 Show fit	13.86	ENST00000311956.4	ARHGAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GTPase activating protein 1
chr7_+_108210012 Show fit	13.82	ENST00000249356.3	DNAJB9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DnaJ (Hsp40) homolog, subfamily B, member 9
chr5_+_130506475 Show fit	13.77	ENST00000379380.4	LYRM7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LYR motif containing 7
chr6_-_159420780 Show fit	13.71	ENST00000449822.1	RSPH3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	radial spoke 3 homolog (Chlamydomonas)
chr8_-_27630102 Show fit	13.51	ENST00000356537.4 ENST00000522915.1 ENST00000539095.1	CCDC25 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 25
chr20_-_48532046 Show fit	13.51	ENST00000543716.1	SPATA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spermatogenesis associated 2
chr15_+_40331456 Show fit	13.44	ENST00000504245.1 ENST00000560341.1	SRP14-AS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SRP14 antisense RNA1 (head to head)
chr14_-_77843390 Show fit	13.16	ENST00000216468.7	TMED8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane emp24 protein transport domain containing 8
chr20_+_49575342 Show fit	13.02	ENST00000244051.1	MOCS3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	molybdenum cofactor synthesis 3
chr19_+_50879705 Show fit	12.90	ENST00000598168.1 ENST00000411902.2 ENST00000253727.5 ENST00000597790.1 ENST00000597130.1 ENST00000599105.1	NR1H2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 1, group H, member 2
chr5_+_161274685 Show fit	12.90	ENST00000428797.2	GABRA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr11_-_71791435 Show fit	12.74	ENST00000351960.6 ENST00000541719.1 ENST00000535111.1	NUMA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear mitotic apparatus protein 1
chr17_-_33905521 Show fit	12.71	ENST00000225873.4	PEX12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	peroxisomal biogenesis factor 12
chr6_-_32095968 Show fit	12.64	ENST00000375203.3 ENST00000375201.4	ATF6B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	activating transcription factor 6 beta
chr16_+_30710462 Show fit	12.47	ENST00000262518.4 ENST00000395059.2 ENST00000344771.4	SRCAP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Snf2-related CREBBP activator protein
chr22_+_38004473 Show fit	12.39	ENST00000414350.3 ENST00000343632.4	GGA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr12_+_9102632 Show fit	12.36	ENST00000539240.1	KLRG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	killer cell lectin-like receptor subfamily G, member 1
chr15_+_90234028 Show fit	12.31	ENST00000268130.7 ENST00000560294.1 ENST00000558000.1	WDR93 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain 93
chr6_+_110012462 Show fit	12.26	ENST00000441478.2 ENST00000230124.3	FIG4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
chr5_-_93447333 Show fit	12.21	ENST00000395965.3 ENST00000505869.1 ENST00000509163.1	FAM172A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 172, member A
chr16_+_19535133 Show fit	12.17	ENST00000396212.2 ENST00000381396.5	CCP110 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	centriolar coiled coil protein 110kDa
chr1_-_109618566 Show fit	12.14	ENST00000338366.5	TAF13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr17_-_18218270 Show fit	12.05	ENST00000321105.5	TOP3A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	topoisomerase (DNA) III alpha
chr14_+_100842735 Show fit	11.97	ENST00000554998.1 ENST00000402312.3 ENST00000335290.6 ENST00000554175.1	WDR25 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain 25
chr16_+_77224732 Show fit	11.96	ENST00000569610.1 ENST00000248248.3 ENST00000567291.1 ENST00000320859.6 ENST00000563612.1 ENST00000563279.1	MON1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MON1 secretory trafficking family member B
chr11_-_71791518 Show fit	11.90	ENST00000537217.1 ENST00000366394.3 ENST00000358965.6 ENST00000546131.1 ENST00000543937.1 ENST00000368959.5 ENST00000541641.1	NUMA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear mitotic apparatus protein 1
chr18_-_47808050 Show fit	11.89	ENST00000590208.1	MBD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	methyl-CpG binding domain protein 1
chr11_+_124492749 Show fit	11.78	ENST00000531667.1 ENST00000441174.3 ENST00000375005.4	TBRG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transforming growth factor beta regulator 1
chr12_-_49110613 Show fit	11.60	ENST00000261900.3	CCNT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin T1
chr14_-_96830207 Show fit	11.53	ENST00000359933.4	ATG2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	autophagy related 2B
chr13_+_31191920 Show fit	11.39	ENST00000255304.4	USPL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin specific peptidase like 1
chr6_-_159421198 Show fit	11.38	ENST00000252655.1 ENST00000297262.3 ENST00000367069.2	RSPH3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	radial spoke 3 homolog (Chlamydomonas)
chr17_+_4843679 Show fit	11.28	ENST00000576229.1	RNF167 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger protein 167
chr1_-_155826967 Show fit	11.28	ENST00000368331.1 ENST00000361040.5 ENST00000271883.5	GON4L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	gon-4-like (C. elegans)
chr2_-_69870747 Show fit	11.26	ENST00000409068.1	AAK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	AP2 associated kinase 1
chr19_+_47852538 Show fit	11.25	ENST00000328771.4	DHX34 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAH (Asp-Glu-Ala-His) box polypeptide 34
chr9_+_140100113 Show fit	11.18	ENST00000371521.4 ENST00000344894.5 ENST00000427047.2 ENST00000458322.2	NDOR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NADPH dependent diflavin oxidoreductase 1
chr2_-_208489707 Show fit	10.97	ENST00000448007.2 ENST00000432416.1 ENST00000411432.1	METTL21A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	methyltransferase like 21A
chr10_-_15902449 Show fit	10.90	ENST00000277632.3	FAM188A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 188, member A
chr2_-_69870835 Show fit	10.82	ENST00000409085.4 ENST00000406297.3	AAK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	AP2 associated kinase 1
chr22_+_22020273 Show fit	10.80	ENST00000412327.1 ENST00000335025.8 ENST00000398831.3 ENST00000492445.2 ENST00000458567.1 ENST00000406385.1	PPIL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	peptidylprolyl isomerase (cyclophilin)-like 2
chr18_+_5238055 Show fit	10.74	ENST00000582363.1 ENST00000582008.1 ENST00000580082.1	LINC00667 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 667
chr20_-_44993012 Show fit	10.60	ENST00000372229.1 ENST00000372230.5 ENST00000543605.1 ENST00000243896.2 ENST00000317734.8	SLC35C2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 35 (GDP-fucose transporter), member C2
chr3_+_47324424 Show fit	10.56	ENST00000437353.1 ENST00000232766.5 ENST00000455924.2	KLHL18 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kelch-like family member 18
chr8_-_42698433 Show fit	10.55	ENST00000345117.2 ENST00000254250.3	THAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	THAP domain containing, apoptosis associated protein 1
chr11_+_47270475 Show fit	10.49	ENST00000481889.2 ENST00000436778.1 ENST00000531660.1 ENST00000407404.1	NR1H3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 1, group H, member 3
chr11_+_131781290 Show fit	10.48	ENST00000425719.2 ENST00000374784.1	NTM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neurotrimin
chr11_+_47270436 Show fit	10.45	ENST00000395397.3 ENST00000405576.1	NR1H3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 1, group H, member 3
chr10_-_124713842 Show fit	10.44	ENST00000481909.1	C10orf88 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 10 open reading frame 88
chr14_-_24711865 Show fit	10.41	ENST00000399423.4 ENST00000267415.7	TINF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TERF1 (TRF1)-interacting nuclear factor 2
chr19_+_37407212 Show fit	10.41	ENST00000427117.1 ENST00000587130.1 ENST00000333987.7 ENST00000415168.1 ENST00000444991.1	ZNF568 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 568
chr7_-_99756293 Show fit	10.36	ENST00000316937.3 ENST00000456769.1	C7orf43 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 7 open reading frame 43
chr6_-_28303901 Show fit	10.28	ENST00000439158.1 ENST00000446474.1 ENST00000414431.1 ENST00000344279.6 ENST00000453745.1	ZSCAN31 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger and SCAN domain containing 31
chr19_+_39881951 Show fit	10.27	ENST00000315588.5 ENST00000594368.1 ENST00000599213.2 ENST00000596297.1	MED29 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mediator complex subunit 29
chr12_+_56401268 Show fit	10.16	ENST00000262032.5	IKZF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	IKAROS family zinc finger 4 (Eos)
chr14_-_24711806 Show fit	10.14	ENST00000540705.1 ENST00000538777.1 ENST00000558566.1 ENST00000559019.1	TINF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TERF1 (TRF1)-interacting nuclear factor 2
chr5_+_149737202 Show fit	10.09	ENST00000451292.1 ENST00000377797.3 ENST00000445265.2 ENST00000323668.7 ENST00000439160.2 ENST00000394269.3 ENST00000427724.2 ENST00000504761.2 ENST00000513346.1 ENST00000515516.1	TCOF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Treacher Collins-Franceschetti syndrome 1
chr22_+_47158518 Show fit	10.00	ENST00000337137.4 ENST00000380995.1 ENST00000407381.3	TBC1D22A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TBC1 domain family, member 22A
chr2_-_9563575 Show fit	9.96	ENST00000488451.1 ENST00000238091.4 ENST00000355346.4	ITGB1BP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin beta 1 binding protein 1
chr1_+_28655505 Show fit	9.93	ENST00000373842.4 ENST00000398997.2	MED18 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mediator complex subunit 18
chr7_-_91509986 Show fit	9.92	ENST00000456229.1 ENST00000442961.1 ENST00000406735.2 ENST00000419292.1 ENST00000351870.3	MTERF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial transcription termination factor
chr8_+_117778736 Show fit	9.67	ENST00000309822.2 ENST00000357148.3 ENST00000517814.1 ENST00000517820.1	UTP23 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UTP23, small subunit (SSU) processome component, homolog (yeast)
chr9_-_77567743 Show fit	9.60	ENST00000376854.5	C9orf40 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 9 open reading frame 40
chr8_+_22462145 Show fit	9.58	ENST00000308511.4 ENST00000523801.1 ENST00000521301.1	CCAR2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell cycle and apoptosis regulator 2
chr15_+_76196200 Show fit	9.53	ENST00000308275.3 ENST00000453211.2	FBXO22 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	F-box protein 22
chr20_+_58515417 Show fit	9.45	ENST00000360816.3	FAM217B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 217, member B
chr11_-_61197187 Show fit	9.30	ENST00000449811.1 ENST00000413232.1 ENST00000340437.4 ENST00000539952.1 ENST00000544585.1 ENST00000450000.1	CPSF7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cleavage and polyadenylation specific factor 7, 59kDa
chr6_+_41040678 Show fit	9.18	ENST00000341376.6 ENST00000353205.5	NFYA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear transcription factor Y, alpha
chr3_-_48936272 Show fit	9.13	ENST00000544097.1 ENST00000430379.1 ENST00000319017.4	SLC25A20 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr2_-_196933536 Show fit	9.07	ENST00000312428.6 ENST00000410072.1	DNAH7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dynein, axonemal, heavy chain 7
chr14_+_74417192 Show fit	9.04	ENST00000554320.1	COQ6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	coenzyme Q6 monooxygenase
chr15_+_43425672 Show fit	9.00	ENST00000260403.2	TMEM62 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 62
chr16_+_66968343 Show fit	8.95	ENST00000417689.1 ENST00000561697.1 ENST00000317091.4 ENST00000566182.1	CES2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	carboxylesterase 2
chr4_-_76439596 Show fit	8.88	ENST00000451788.1 ENST00000512706.1	RCHY1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr15_-_90234006 Show fit	8.68	ENST00000300056.3 ENST00000559170.1	PEX11A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	peroxisomal biogenesis factor 11 alpha
chr11_-_47270341 Show fit	8.66	ENST00000529444.1 ENST00000530453.1 ENST00000537863.1 ENST00000529788.1 ENST00000444355.2 ENST00000527256.1 ENST00000529663.1 ENST00000256997.3	ACP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	acid phosphatase 2, lysosomal
chr7_+_74508372 Show fit	8.65	ENST00000356115.5 ENST00000430511.2 ENST00000312575.7	GTF2IRD2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GTF2I repeat domain containing 2B
chr8_+_22462532 Show fit	8.65	ENST00000389279.3	CCAR2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell cycle and apoptosis regulator 2
chr12_+_123868320 Show fit	8.56	ENST00000402868.3 ENST00000330479.4	SETD8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SET domain containing (lysine methyltransferase) 8
chr1_+_43855560 Show fit	8.50	ENST00000562955.1	SZT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	seizure threshold 2 homolog (mouse)
chrX_+_54556633 Show fit	8.48	ENST00000336470.4 ENST00000360845.2	GNL3L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	guanine nucleotide binding protein-like 3 (nucleolar)-like
chr11_-_61197480 Show fit	8.41	ENST00000439958.3 ENST00000394888.4	CPSF7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cleavage and polyadenylation specific factor 7, 59kDa
chr11_+_63606477 Show fit	8.31	ENST00000508192.1 ENST00000361128.5	MARK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MAP/microtubule affinity-regulating kinase 2
chr11_+_2421718 Show fit	8.30	ENST00000380996.5 ENST00000333256.6 ENST00000380992.1 ENST00000437110.1 ENST00000435795.1	TSSC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor suppressing subtransferable candidate 4
chr2_-_27886676 Show fit	8.27	ENST00000337768.5	SUPT7L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	suppressor of Ty 7 (S. cerevisiae)-like

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
27.0	81.1	GO:0007439	ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
10.5	31.6	GO:0071988	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
9.2	27.7	GO:2000870	regulation of progesterone secretion(GO:2000870)
8.2	41.1	GO:0033274	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
7.5	37.7	GO:0036369	transcription factor catabolic process(GO:0036369)
7.0	28.0	GO:0032053	ciliary basal body organization(GO:0032053)
7.0	20.9	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
6.5	12.9	GO:0090182	regulation of secretion of lysosomal enzymes(GO:0090182)
5.3	15.9	GO:0034227	tRNA thio-modification(GO:0034227)
5.2	41.4	GO:1901525	negative regulation of macromitophagy(GO:1901525)
4.8	43.6	GO:0006531	aspartate metabolic process(GO:0006531)
4.6	13.9	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
3.9	30.9	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
3.9	15.4	GO:0044375	regulation of peroxisome size(GO:0044375)
3.6	3.6	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
3.6	10.7	GO:0018283	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
3.4	43.6	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
3.3	9.9	GO:1902019	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
3.3	16.4	GO:0035900	response to isolation stress(GO:0035900)
3.3	9.8	GO:0097359	UDP-glucosylation(GO:0097359)
3.3	6.5	GO:0071284	cellular response to lead ion(GO:0071284)
3.2	13.0	GO:1904379	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
3.2	19.2	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
3.0	6.1	GO:0016559	peroxisome fission(GO:0016559)
3.0	12.0	GO:0019086	late viral transcription(GO:0019086)
2.8	5.7	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
2.8	14.1	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
2.7	48.4	GO:0042424	catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
2.6	28.8	GO:0035330	regulation of hippo signaling(GO:0035330)
2.5	10.0	GO:0051344	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
2.5	22.2	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
2.4	43.5	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
2.4	19.1	GO:0032790	ribosome disassembly(GO:0032790)
2.4	19.0	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
2.3	6.8	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
2.2	35.3	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
2.2	8.7	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
2.2	13.0	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
2.1	14.6	GO:0007256	activation of JNKK activity(GO:0007256)
2.1	6.2	GO:0007077	mitotic nuclear envelope disassembly(GO:0007077)
2.0	26.3	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
2.0	16.1	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
2.0	21.5	GO:0045023	G0 to G1 transition(GO:0045023)
1.9	11.4	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.7	17.4	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
1.7	8.5	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
1.6	4.9	GO:0051102	DNA ligation involved in DNA recombination(GO:0051102)
1.6	9.7	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
1.6	8.1	GO:2000845	testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
1.6	16.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
1.6	67.7	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
1.6	4.7	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
1.6	17.1	GO:0060363	cranial suture morphogenesis(GO:0060363)
1.5	44.8	GO:0006884	cell volume homeostasis(GO:0006884)
1.5	12.3	GO:0031642	negative regulation of myelination(GO:0031642)
1.5	7.6	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
1.5	5.9	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
1.4	11.4	GO:0016926	protein desumoylation(GO:0016926)
1.4	7.0	GO:0034472	snRNA 3'-end processing(GO:0034472)
1.3	8.0	GO:0098828	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
1.3	41.3	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
1.2	11.2	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.2	21.1	GO:0006265	DNA topological change(GO:0006265)
1.2	4.9	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.2	7.3	GO:0071105	response to interleukin-11(GO:0071105)
1.2	9.5	GO:0017185	peptidyl-lysine hydroxylation(GO:0017185)
1.1	25.1	GO:0030488	tRNA methylation(GO:0030488)
1.1	21.6	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
1.1	9.1	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
1.1	22.4	GO:0031167	rRNA methylation(GO:0031167)
1.1	5.6	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
1.1	24.2	GO:0006895	Golgi to endosome transport(GO:0006895)
1.0	4.1	GO:1903936	response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
1.0	6.2	GO:0060011	sperm ejaculation(GO:0042713) Sertoli cell proliferation(GO:0060011)
1.0	25.6	GO:0006829	zinc II ion transport(GO:0006829)
1.0	8.1	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
1.0	11.0	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
1.0	12.6	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.9	0.9	GO:0090035	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.9	9.1	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.9	5.4	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.9	22.1	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.9	13.9	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.9	17.9	GO:0044804	nucleophagy(GO:0044804)
0.8	8.5	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.8	15.3	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.8	12.0	GO:0016576	histone dephosphorylation(GO:0016576)
0.8	64.8	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.8	10.1	GO:0014029	neural crest formation(GO:0014029)
0.8	15.4	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.7	8.2	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.7	6.0	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.7	9.5	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.7	2.1	GO:0048213	Golgi vesicle prefusion complex stabilization(GO:0048213)
0.7	28.3	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.7	26.1	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.7	15.6	GO:0032607	interferon-alpha production(GO:0032607)
0.6	12.9	GO:0071420	cellular response to histamine(GO:0071420)
0.6	6.4	GO:1904424	regulation of GTP binding(GO:1904424)
0.6	14.7	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.6	19.0	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.6	8.7	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.6	4.2	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.6	1.2	GO:0070197	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.6	4.5	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.6	32.1	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.6	6.7	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.6	9.5	GO:0046069	cGMP catabolic process(GO:0046069)
0.6	8.3	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692)
0.5	10.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.5	15.9	GO:0060325	face morphogenesis(GO:0060325)
0.5	2.5	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.5	16.7	GO:0006400	tRNA modification(GO:0006400)
0.5	16.6	GO:0050890	cognition(GO:0050890)
0.5	6.5	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.5	26.6	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.5	9.1	GO:0006853	carnitine shuttle(GO:0006853)
0.5	1.8	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.4	20.2	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.4	25.3	GO:0060976	coronary vasculature development(GO:0060976)
0.4	6.5	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.4	3.9	GO:2000049	positive regulation of cell adhesion molecule production(GO:0060355) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.4	19.5	GO:0051646	mitochondrion localization(GO:0051646)
0.4	14.0	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.4	9.7	GO:0043101	purine-containing compound salvage(GO:0043101)
0.3	6.9	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.3	2.6	GO:0051601	exocyst localization(GO:0051601)
0.3	6.2	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.3	4.9	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.3	1.8	GO:0001692	histamine metabolic process(GO:0001692)
0.3	8.2	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.3	2.0	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.3	7.4	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.3	14.3	GO:0033344	cholesterol efflux(GO:0033344)
0.3	3.6	GO:0045008	depyrimidination(GO:0045008)
0.3	15.7	GO:0016579	protein deubiquitination(GO:0016579)
0.3	5.3	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.3	7.9	GO:0051262	protein tetramerization(GO:0051262)
0.3	38.6	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968)
0.2	1.7	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.2	10.5	GO:0008038	neuron recognition(GO:0008038)
0.2	1.4	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.2	9.0	GO:0006692	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.2	7.8	GO:0022400	regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.2	0.2	GO:0021997	neural plate axis specification(GO:0021997)
0.2	5.7	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.2	6.2	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.2	18.2	GO:0007041	lysosomal transport(GO:0007041)
0.2	21.0	GO:0000209	protein polyubiquitination(GO:0000209)
0.2	2.3	GO:0015074	DNA integration(GO:0015074)
0.2	7.2	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.2	10.1	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2	20.9	GO:0001935	endothelial cell proliferation(GO:0001935)
0.2	9.2	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.2	0.6	GO:0021539	subthalamus development(GO:0021539)
0.1	4.4	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	1.7	GO:0006108	oxaloacetate metabolic process(GO:0006107) malate metabolic process(GO:0006108)
0.1	4.7	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	4.0	GO:0035666	TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.1	10.9	GO:1901655	cellular response to ketone(GO:1901655)
0.1	5.0	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.1	6.0	GO:0002456	T cell mediated immunity(GO:0002456)
0.1	3.9	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	6.2	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1	4.5	GO:1901998	toxin transport(GO:1901998)
0.1	2.9	GO:0097421	liver regeneration(GO:0097421)
0.1	11.3	GO:0030183	B cell differentiation(GO:0030183)
0.1	15.9	GO:0042098	T cell proliferation(GO:0042098)
0.1	1.2	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1	7.9	GO:0043462	regulation of ATPase activity(GO:0043462)
0.1	2.8	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	3.8	GO:0030032	lamellipodium assembly(GO:0030032)
0.1	1.2	GO:2000772	regulation of cellular senescence(GO:2000772)
0.1	2.0	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.1	7.6	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1	4.9	GO:0006469	negative regulation of protein kinase activity(GO:0006469)
0.0	1.2	GO:0008214	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0	0.2	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.7	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	2.2	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	3.8	GO:0030010	establishment of cell polarity(GO:0030010)
0.0	3.7	GO:0051384	response to glucocorticoid(GO:0051384)
0.0	6.8	GO:0018105	peptidyl-serine phosphorylation(GO:0018105)
0.0	0.7	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	2.7	GO:0021987	cerebral cortex development(GO:0021987)
0.0	2.0	GO:0006968	cellular defense response(GO:0006968)
0.0	11.0	GO:0001501	skeletal system development(GO:0001501)
0.0	0.8	GO:0090383	phagosome acidification(GO:0090383)
0.0	10.5	GO:0048232	spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0	5.2	GO:0030198	extracellular matrix organization(GO:0030198)
0.0	1.0	GO:0006954	inflammatory response(GO:0006954)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
23.9	95.7	GO:1990745	EARP complex(GO:1990745)
10.5	31.6	GO:0061673	cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
10.4	41.4	GO:0033596	TSC1-TSC2 complex(GO:0033596)
6.2	31.2	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)
6.1	18.2	GO:0044609	DBIRD complex(GO:0044609)
5.5	27.5	GO:0010370	perinucleolar chromocenter(GO:0010370)
4.3	17.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
3.2	13.0	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
3.2	16.1	GO:0070847	core mediator complex(GO:0070847)
3.2	15.8	GO:0000801	central element(GO:0000801)
2.7	18.6	GO:0097427	microtubule bundle(GO:0097427)
2.6	15.9	GO:0032807	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
2.5	15.3	GO:1990769	proximal neuron projection(GO:1990769)
2.1	8.3	GO:0032044	DSIF complex(GO:0032044)
2.0	8.1	GO:0055087	Ski complex(GO:0055087)
2.0	15.9	GO:0005672	transcription factor TFIIA complex(GO:0005672)
1.7	6.9	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.6	9.7	GO:1902560	GMP reductase complex(GO:1902560)
1.5	6.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
1.4	8.7	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
1.4	7.2	GO:0045298	tubulin complex(GO:0045298)
1.4	8.5	GO:1990130	Iml1 complex(GO:1990130)
1.3	4.0	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
1.3	33.6	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
1.2	37.7	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
1.2	8.2	GO:0070419	nonhomologous end joining complex(GO:0070419)
1.2	15.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
1.2	11.6	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
1.2	12.7	GO:0097443	sorting endosome(GO:0097443)
1.1	9.9	GO:0034464	BBSome(GO:0034464)
0.9	11.4	GO:0005642	annulate lamellae(GO:0005642)
0.9	3.7	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.8	9.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.8	6.4	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.8	14.3	GO:0031083	BLOC-1 complex(GO:0031083)
0.8	7.0	GO:0032039	integrator complex(GO:0032039)
0.7	16.9	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.7	8.2	GO:0030914	STAGA complex(GO:0030914)
0.7	2.0	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.7	8.0	GO:0060077	inhibitory synapse(GO:0060077)
0.7	2.6	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.6	9.1	GO:0005858	axonemal dynein complex(GO:0005858)
0.6	43.4	GO:0015030	Cajal body(GO:0015030)
0.6	14.7	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.6	16.3	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.4	51.5	GO:0016605	PML body(GO:0016605)
0.4	12.9	GO:1902711	GABA-A receptor complex(GO:1902711)
0.4	49.0	GO:0031902	late endosome membrane(GO:0031902)
0.4	7.6	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.4	7.2	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.4	18.7	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.3	9.8	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.3	3.2	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.3	40.1	GO:0031901	early endosome membrane(GO:0031901)
0.3	4.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.3	3.9	GO:0016600	flotillin complex(GO:0016600)
0.3	1.2	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.3	39.1	GO:0005796	Golgi lumen(GO:0005796)
0.3	2.7	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.3	22.1	GO:0043195	terminal bouton(GO:0043195)
0.3	28.3	GO:0005814	centriole(GO:0005814)
0.2	10.6	GO:0097546	ciliary base(GO:0097546)
0.2	1.7	GO:0000322	storage vacuole(GO:0000322)
0.2	5.4	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.2	2.0	GO:0017119	Golgi transport complex(GO:0017119)
0.2	8.7	GO:0005801	cis-Golgi network(GO:0005801)
0.2	4.7	GO:0005680	anaphase-promoting complex(GO:0005680)
0.2	6.9	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	53.8	GO:0000790	nuclear chromatin(GO:0000790)
0.1	54.3	GO:0016324	apical plasma membrane(GO:0016324)
0.1	4.2	GO:0016592	mediator complex(GO:0016592)
0.1	7.4	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	0.9	GO:0042405	ubiquitin conjugating enzyme complex(GO:0031371) nuclear inclusion body(GO:0042405)
0.1	6.1	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	11.3	GO:0055037	recycling endosome(GO:0055037)
0.1	2.6	GO:0030686	90S preribosome(GO:0030686)
0.1	10.5	GO:0031225	anchored component of membrane(GO:0031225)
0.1	1.0	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	25.3	GO:0045202	synapse(GO:0045202)
0.1	7.5	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.1	9.5	GO:0032587	ruffle membrane(GO:0032587)
0.1	7.0	GO:0043202	lysosomal lumen(GO:0043202)
0.1	1.2	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	10.1	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.1	0.6	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1	3.7	GO:0016234	inclusion body(GO:0016234)
0.1	1.7	GO:0043198	dendritic shaft(GO:0043198)
0.0	6.9	GO:0030018	Z disc(GO:0030018)
0.0	175.1	GO:0016021	integral component of membrane(GO:0016021)
0.0	4.8	GO:0001650	fibrillar center(GO:0001650)
0.0	2.1	GO:0001726	ruffle(GO:0001726)
0.0	2.4	GO:0005769	early endosome(GO:0005769)
0.0	32.4	GO:0005615	extracellular space(GO:0005615)
0.0	7.9	GO:0005794	Golgi apparatus(GO:0005794)
0.0	1.5	GO:0005788	endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.5	43.6	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
10.1	50.5	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
9.4	37.7	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
8.2	41.1	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
7.4	7.4	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
6.9	48.4	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
6.3	19.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
5.5	16.4	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
5.2	20.9	GO:0032810	sterol response element binding(GO:0032810)
5.1	30.5	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
5.1	15.2	GO:0045322	unmethylated CpG binding(GO:0045322)
4.6	13.9	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
3.3	9.8	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
3.1	12.3	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
3.0	9.1	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
2.9	67.7	GO:0070008	serine-type exopeptidase activity(GO:0070008)
2.9	35.3	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
2.7	32.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
2.6	12.9	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
2.4	30.7	GO:0051011	microtubule minus-end binding(GO:0051011)
2.3	41.9	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
2.2	6.5	GO:0015039	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
2.2	6.5	GO:0032767	copper-dependent protein binding(GO:0032767)
2.2	13.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
2.1	25.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
2.0	44.8	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
2.0	6.0	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
2.0	43.5	GO:0070300	phosphatidic acid binding(GO:0070300)
1.9	11.4	GO:0035800	deubiquitinase activator activity(GO:0035800)
1.8	9.0	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
1.7	27.8	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
1.6	9.7	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
1.6	12.9	GO:1904315	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
1.6	17.6	GO:0001042	RNA polymerase I core binding(GO:0001042)
1.6	17.4	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
1.5	22.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
1.4	11.6	GO:0097322	7SK snRNA binding(GO:0097322)
1.4	11.4	GO:0016929	SUMO-specific protease activity(GO:0016929)
1.4	26.8	GO:0051787	misfolded protein binding(GO:0051787)
1.4	4.2	GO:0071566	UFM1 activating enzyme activity(GO:0071566)
1.4	6.9	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
1.4	13.6	GO:0016783	sulfurtransferase activity(GO:0016783)
1.3	14.7	GO:0046935	phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.3	35.2	GO:0003746	translation elongation factor activity(GO:0003746)
1.2	11.2	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
1.0	6.2	GO:0098821	BMP receptor activity(GO:0098821)
1.0	8.2	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
1.0	8.1	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
1.0	9.9	GO:0034452	dynactin binding(GO:0034452)
0.9	18.6	GO:0050321	tau-protein kinase activity(GO:0050321)
0.9	150.9	GO:0017137	Rab GTPase binding(GO:0017137)
0.8	10.6	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.8	20.8	GO:0070566	adenylyltransferase activity(GO:0070566)
0.7	4.9	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.7	17.6	GO:0016805	dipeptidase activity(GO:0016805)
0.6	1.8	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.6	30.3	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.6	9.1	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.6	15.0	GO:0071949	FAD binding(GO:0071949)
0.6	6.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.5	3.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.5	4.7	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.5	14.6	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.5	13.9	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.5	4.9	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.5	35.5	GO:0001540	beta-amyloid binding(GO:0001540)
0.5	3.7	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.5	8.3	GO:0017049	GTP-Rho binding(GO:0017049)
0.4	27.7	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.4	9.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.4	5.5	GO:0008417	fucosyltransferase activity(GO:0008417)
0.4	4.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.3	1.4	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.3	22.5	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.3	1.7	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.3	9.5	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.3	18.1	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.3	4.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.3	5.3	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.3	3.7	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.3	18.8	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.3	11.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.3	4.9	GO:0070513	death domain binding(GO:0070513)
0.3	6.3	GO:0004707	MAP kinase activity(GO:0004707)
0.3	20.3	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.3	9.7	GO:0005484	SNAP receptor activity(GO:0005484)
0.3	4.1	GO:0032183	SUMO binding(GO:0032183)
0.2	11.9	GO:0042162	telomeric DNA binding(GO:0042162)
0.2	8.2	GO:0019887	protein kinase regulator activity(GO:0019887)
0.2	34.3	GO:0031267	small GTPase binding(GO:0031267)
0.2	10.2	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.2	4.6	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.2	85.8	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.2	28.2	GO:0044325	ion channel binding(GO:0044325)
0.2	2.9	GO:0043422	protein kinase B binding(GO:0043422)
0.1	16.6	GO:0008234	cysteine-type peptidase activity(GO:0008234)
0.1	21.0	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	9.2	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1	6.9	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1	5.9	GO:0051082	unfolded protein binding(GO:0051082)
0.1	127.2	GO:0003700	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1	2.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.7	GO:1990932	5.8S rRNA binding(GO:1990932)
0.1	0.6	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1	10.8	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.1	2.0	GO:0051879	Hsp90 protein binding(GO:0051879)
0.1	3.9	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.1	3.9	GO:0042169	SH2 domain binding(GO:0042169)
0.1	2.6	GO:0050681	androgen receptor binding(GO:0050681)
0.1	6.3	GO:0051087	chaperone binding(GO:0051087)
0.1	14.7	GO:0000287	magnesium ion binding(GO:0000287)
0.1	1.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	6.0	GO:0019903	protein phosphatase binding(GO:0019903)
0.1	1.2	GO:0031490	chromatin DNA binding(GO:0031490)
0.1	4.5	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1	1.8	GO:0008170	N-methyltransferase activity(GO:0008170)
0.0	5.6	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	147.5	GO:0046872	metal ion binding(GO:0046872)
0.0	1.7	GO:0097110	scaffold protein binding(GO:0097110)
0.0	0.4	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	15.9	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.0	0.2	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	1.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.2	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.9	GO:0008168	methyltransferase activity(GO:0008168)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	41.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.8	33.8	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.6	37.0	PID FANCONI PATHWAY	Fanconi anemia pathway
0.6	15.8	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.5	46.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.5	45.2	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.5	40.2	PID P53 REGULATION PATHWAY	p53 pathway
0.4	36.3	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.4	37.8	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.3	18.6	PID LKB1 PATHWAY	LKB1 signaling events
0.3	19.1	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.3	27.3	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.3	6.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.3	13.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.3	28.4	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.3	8.2	PID MYC PATHWAY	C-MYC pathway
0.2	6.3	ST GA12 PATHWAY	G alpha 12 Pathway
0.2	21.4	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.2	5.8	PID IL1 PATHWAY	IL1-mediated signaling events
0.2	9.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.2	6.2	PID ALK1 PATHWAY	ALK1 signaling events
0.2	7.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	4.3	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	8.1	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	6.7	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	5.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	3.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	33.3	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	3.8	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	1.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.4	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.9	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.0	29.7	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
2.2	41.4	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
2.0	31.6	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
1.5	108.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
1.2	10.5	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.9	15.9	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.7	14.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.7	9.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.6	27.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.5	7.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.5	19.0	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.5	14.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.5	7.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.5	17.9	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.5	39.5	REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	Genes involved in RNA Polymerase II Pre-transcription Events
0.4	4.7	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.4	12.9	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.4	16.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.4	4.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.4	7.6	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4	6.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.4	9.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.4	33.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.3	9.7	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3	6.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.3	22.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3	9.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3	6.5	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.3	31.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.3	10.8	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.3	5.6	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.3	10.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	54.2	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.2	9.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.2	4.7	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.2	3.6	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2	4.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2	8.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.2	6.0	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.2	3.8	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	15.3	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.1	2.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	2.9	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.1	4.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.0	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	8.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.9	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.8	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.5	REACTOME ACTIVATED TLR4 SIGNALLING	Genes involved in Activated TLR4 signalling
0.0	0.9	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis