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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for FOSB

Z-value: 0.83

Motif logo

Transcription factors associated with FOSB

Gene Symbol Gene ID Gene Info
ENSG00000125740.9 FosB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSBhg19_v2_chr19_+_45971246_45971265-0.203.5e-03Click!

Activity profile of FOSB motif

Sorted Z-values of FOSB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_31704282 21.04 ENST00000375784.3
ENST00000375779.2
chloride intracellular channel 1
chr17_-_73150629 19.46 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
hematological and neurological expressed 1
chr14_+_103801140 17.22 ENST00000561325.1
ENST00000392715.2
ENST00000559130.1
ENST00000559532.1
ENST00000558506.1
eukaryotic translation initiation factor 5
chr1_-_24126023 16.68 ENST00000429356.1
UDP-galactose-4-epimerase
chr1_+_165796753 16.30 ENST00000367879.4
uridine-cytidine kinase 2
chr1_+_223889285 14.40 ENST00000433674.2
calpain 2, (m/II) large subunit
chr1_+_26606608 14.07 ENST00000319041.6
SH3 domain binding glutamic acid-rich protein like 3
chr1_-_113247543 14.05 ENST00000414971.1
ENST00000534717.1
ras homolog family member C
chr11_-_64013288 13.80 ENST00000542235.1
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr3_+_183894566 13.53 ENST00000439647.1
adaptor-related protein complex 2, mu 1 subunit
chr1_+_223900034 13.09 ENST00000295006.5
calpain 2, (m/II) large subunit
chr11_-_65667997 12.82 ENST00000312562.2
ENST00000534222.1
FOS-like antigen 1
chr11_-_65667884 12.36 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOS-like antigen 1
chr6_+_44194762 11.55 ENST00000371708.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr3_-_81792780 11.54 ENST00000489715.1
glucan (1,4-alpha-), branching enzyme 1
chr16_-_69760409 10.92 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NAD(P)H dehydrogenase, quinone 1
chr8_+_26150628 10.57 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr17_-_79481666 10.26 ENST00000575659.1
actin, gamma 1
chr17_+_35851570 10.25 ENST00000394386.1
dual specificity phosphatase 14
chr15_-_60690163 10.02 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
annexin A2
chr6_-_38670897 10.01 ENST00000373365.4
glyoxalase I
chr5_+_72143988 9.89 ENST00000506351.2
transportin 1
chr16_+_89988259 9.80 ENST00000554444.1
ENST00000556565.1
Tubulin beta-3 chain
chr6_+_106959718 9.71 ENST00000369066.3
absent in melanoma 1
chr14_-_23426337 9.65 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS augmin-like complex, subunit 4
chr17_+_79650962 9.54 ENST00000329138.4
hepatocyte growth factor-regulated tyrosine kinase substrate
chr14_-_23426322 9.50 ENST00000555367.1
HAUS augmin-like complex, subunit 4
chr6_-_35888905 9.22 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRSF protein kinase 1
chr10_+_88854926 9.22 ENST00000298784.1
ENST00000298786.4
family with sequence similarity 35, member A
chr14_-_23426270 9.00 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS augmin-like complex, subunit 4
chr16_+_30751953 8.99 ENST00000483578.1
RP11-2C24.4
chr5_+_135394840 8.83 ENST00000503087.1
transforming growth factor, beta-induced, 68kDa
chr3_-_141747439 8.48 ENST00000467667.1
transcription factor Dp-2 (E2F dimerization partner 2)
chrX_-_153285251 7.64 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
interleukin-1 receptor-associated kinase 1
chr7_+_112063192 7.57 ENST00000005558.4
interferon-related developmental regulator 1
chr6_-_35888824 7.13 ENST00000361690.3
ENST00000512445.1
SRSF protein kinase 1
chr7_+_39663061 7.10 ENST00000005257.2
v-ral simian leukemia viral oncogene homolog A (ras related)
chr18_+_21452964 7.07 ENST00000587184.1
laminin, alpha 3
chr5_+_159436120 6.89 ENST00000522793.1
ENST00000231238.5
tetratricopeptide repeat domain 1
chr1_+_156095951 6.77 ENST00000448611.2
ENST00000368297.1
lamin A/C
chr3_-_141747950 6.58 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr18_+_21452804 6.56 ENST00000269217.6
laminin, alpha 3
chr1_+_26869597 6.44 ENST00000530003.1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr3_-_149293990 6.41 ENST00000472417.1
WW domain containing transcription regulator 1
chr11_-_66103867 6.36 ENST00000424433.2
Ras and Rab interactor 1
chr7_-_102985035 6.27 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DnaJ (Hsp40) homolog, subfamily C, member 2
chr22_-_32058166 6.27 ENST00000435900.1
ENST00000336566.4
phosphatidylserine decarboxylase
chr11_-_102668879 5.87 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr2_+_216974020 5.85 ENST00000392132.2
ENST00000417391.1
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr17_+_57697216 5.75 ENST00000393043.1
ENST00000269122.3
clathrin, heavy chain (Hc)
chr12_+_53693466 5.71 ENST00000267103.5
ENST00000548632.1
chromosome 12 open reading frame 10
chr14_+_73525144 5.70 ENST00000261973.7
ENST00000540173.1
RNA binding motif protein 25
chr2_-_85641162 5.61 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
capping protein (actin filament), gelsolin-like
chr19_+_49377575 5.59 ENST00000600406.1
protein phosphatase 1, regulatory subunit 15A
chr19_-_44174330 5.48 ENST00000340093.3
plasminogen activator, urokinase receptor
chr6_+_2988847 5.34 ENST00000380472.3
ENST00000605901.1
ENST00000454015.1
NAD(P)H dehydrogenase, quinone 2
long intergenic non-protein coding RNA 1011
chr3_+_157828152 5.25 ENST00000476899.1
arginine/serine-rich coiled-coil 1
chr15_+_22892663 5.24 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
cytoplasmic FMR1 interacting protein 1
chr3_-_113465065 5.15 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_-_136633940 5.11 ENST00000264156.2
minichromosome maintenance complex component 6
chr15_+_75335604 5.07 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr12_-_118628350 5.06 ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr14_-_75536182 4.90 ENST00000555463.1
acylphosphatase 1, erythrocyte (common) type
chr3_+_113465866 4.83 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr19_+_47104493 4.74 ENST00000291295.9
ENST00000597743.1
calmodulin 3 (phosphorylase kinase, delta)
chr7_+_116312411 4.69 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
met proto-oncogene
chr1_+_27189631 4.53 ENST00000339276.4
stratifin
chr19_+_926000 4.43 ENST00000263620.3
AT rich interactive domain 3A (BRIGHT-like)
chr8_-_59572301 4.42 ENST00000038176.3
neutral sphingomyelinase (N-SMase) activation associated factor
chr6_+_125540951 4.21 ENST00000524679.1
tumor protein D52-like 1
chr17_-_72864739 4.09 ENST00000579893.1
ENST00000544854.1
ferredoxin reductase
chr9_+_140135665 4.04 ENST00000340384.4
tubulin, beta 4B class IVb
chr14_+_73525229 4.02 ENST00000527432.1
ENST00000531500.1
ENST00000525321.1
ENST00000526754.1
RNA binding motif protein 25
chr12_+_64798095 4.02 ENST00000332707.5
exportin, tRNA
chr1_+_174844645 3.95 ENST00000486220.1
RAB GTPase activating protein 1-like
chr5_-_176923803 3.93 ENST00000506161.1
PDZ and LIM domain 7 (enigma)
chr17_+_21191341 3.89 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
mitogen-activated protein kinase kinase 3
chr10_+_17270214 3.86 ENST00000544301.1
vimentin
chr15_+_67458357 3.85 ENST00000537194.2
SMAD family member 3
chr17_+_30771279 3.67 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr5_-_78809950 3.64 ENST00000334082.6
homer homolog 1 (Drosophila)
chr17_+_75446819 3.62 ENST00000541152.2
ENST00000591704.1
septin 9
chr7_+_55177416 3.62 ENST00000450046.1
ENST00000454757.2
epidermal growth factor receptor
chr16_-_67281413 3.59 ENST00000258201.4
formin homology 2 domain containing 1
chr4_+_74606223 3.55 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr3_-_32022733 3.54 ENST00000438237.2
ENST00000396556.2
oxysterol binding protein-like 10
chr9_+_71819927 3.53 ENST00000535702.1
tight junction protein 2
chr4_-_146019693 3.42 ENST00000514390.1
anaphase promoting complex subunit 10
chr10_+_85899196 3.40 ENST00000372134.3
growth hormone inducible transmembrane protein
chr17_+_75315534 3.37 ENST00000590294.1
ENST00000329047.8
septin 9
chrX_+_123094369 3.31 ENST00000455404.1
ENST00000218089.9
stromal antigen 2
chr9_+_71820057 3.29 ENST00000539225.1
tight junction protein 2
chr5_-_176923846 3.17 ENST00000506537.1
PDZ and LIM domain 7 (enigma)
chr4_+_170581213 3.10 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr19_-_55881741 3.07 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
interleukin 11
chr17_-_27405875 2.88 ENST00000359450.6
TGFB1-induced anti-apoptotic factor 1
chr12_+_57849048 2.88 ENST00000266646.2
inhibin, beta E
chr1_+_156084461 2.84 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
lamin A/C
chr19_-_44174305 2.82 ENST00000601723.1
ENST00000339082.3
plasminogen activator, urokinase receptor
chr3_-_141747459 2.81 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr13_+_76334567 2.72 ENST00000321797.8
LIM domain 7
chr3_-_151034734 2.72 ENST00000260843.4
G protein-coupled receptor 87
chr13_+_76334795 2.71 ENST00000526202.1
ENST00000465261.2
LIM domain 7
chr17_-_79881408 2.65 ENST00000392366.3
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr11_-_2924720 2.63 ENST00000455942.2
solute carrier family 22 (organic cation transporter), member 18 antisense
chr19_+_36630454 2.63 ENST00000246533.3
calpain, small subunit 1
chr9_-_130637244 2.61 ENST00000373156.1
adenylate kinase 1
chr8_-_30585217 2.61 ENST00000520888.1
ENST00000414019.1
glutathione reductase
chr15_+_67418047 2.50 ENST00000540846.2
SMAD family member 3
chr1_+_156096336 2.45 ENST00000504687.1
ENST00000473598.2
lamin A/C
chr7_-_20256965 2.39 ENST00000400331.5
ENST00000332878.4
metastasis associated in colon cancer 1
chr2_+_102618428 2.36 ENST00000457817.1
interleukin 1 receptor, type II
chr16_-_67867749 2.22 ENST00000566758.1
ENST00000445712.2
ENST00000219172.3
ENST00000564817.1
centromere protein T
chr1_-_160231451 2.21 ENST00000495887.1
DDB1 and CUL4 associated factor 8
chr1_-_153521597 2.16 ENST00000368712.1
S100 calcium binding protein A3
chr18_+_61143994 2.14 ENST00000382771.4
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr17_-_48785216 2.12 ENST00000285243.6
ankyrin repeat domain 40
chr17_+_46970134 2.04 ENST00000503641.1
ENST00000514808.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr7_+_73624327 2.03 ENST00000361082.3
ENST00000275635.7
ENST00000470709.1
linker for activation of T cells family, member 2
chr9_+_137218362 1.99 ENST00000481739.1
retinoid X receptor, alpha
chr17_-_18161870 1.93 ENST00000579294.1
ENST00000545457.2
ENST00000379450.4
ENST00000578558.1
flightless I homolog (Drosophila)
chr6_-_24877490 1.92 ENST00000540914.1
ENST00000378023.4
family with sequence similarity 65, member B
chr17_+_46970178 1.85 ENST00000393366.2
ENST00000506855.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr19_+_47104553 1.81 ENST00000598871.1
ENST00000594523.1
calmodulin 3 (phosphorylase kinase, delta)
chr1_-_93257951 1.76 ENST00000543509.1
ENST00000370331.1
ENST00000540033.1
ecotropic viral integration site 5
chr4_-_100356844 1.70 ENST00000437033.2
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr13_+_102142296 1.69 ENST00000376162.3
integrin, beta-like 1 (with EGF-like repeat domains)
chr17_+_46970127 1.66 ENST00000355938.5
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr9_-_114246635 1.58 ENST00000338205.5
KIAA0368
chr7_+_150065278 1.58 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
replication initiator 1
chr7_+_120590803 1.55 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
inhibitor of growth family, member 3
chr11_-_2193025 1.53 ENST00000333684.5
ENST00000381178.1
ENST00000381175.1
ENST00000352909.3
tyrosine hydroxylase
chr3_+_100428316 1.52 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TRK-fused gene
chr5_+_43602750 1.47 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
nicotinamide nucleotide transhydrogenase
chr17_-_27503770 1.46 ENST00000533112.1
myosin XVIIIA
chr2_-_65593784 1.42 ENST00000443619.2
sprouty-related, EVH1 domain containing 2
chr13_-_52027134 1.42 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chr12_+_120972606 1.42 ENST00000413266.2
ring finger protein 10
chr1_+_101003687 1.42 ENST00000315033.4
G protein-coupled receptor 88
chr8_-_143823816 1.40 ENST00000246515.1
secreted LY6/PLAUR domain containing 1
chr12_-_49351303 1.39 ENST00000256682.4
ADP-ribosylation factor 3
chr17_-_38721711 1.34 ENST00000578085.1
ENST00000246657.2
chemokine (C-C motif) receptor 7
chr1_+_247579451 1.34 ENST00000391828.3
ENST00000366497.2
NLR family, pyrin domain containing 3
chr12_-_15114492 1.33 ENST00000541546.1
Rho GDP dissociation inhibitor (GDI) beta
chr8_-_42623747 1.33 ENST00000534622.1
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr2_+_46926048 1.31 ENST00000306503.5
suppressor of cytokine signaling 5
chr17_+_7123125 1.28 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
acyl-CoA dehydrogenase, very long chain
chr15_+_40531621 1.28 ENST00000560346.1
p21 protein (Cdc42/Rac)-activated kinase 6
chr4_-_100356551 1.27 ENST00000209665.4
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chrX_+_41193407 1.26 ENST00000457138.2
ENST00000441189.2
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr3_-_49395705 1.25 ENST00000419349.1
glutathione peroxidase 1
chr16_+_57662419 1.25 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
G protein-coupled receptor 56
chr12_-_49351228 1.19 ENST00000541959.1
ENST00000447318.2
ADP-ribosylation factor 3
chr12_-_8765446 1.18 ENST00000537228.1
ENST00000229335.6
activation-induced cytidine deaminase
chr12_+_7023491 1.16 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr1_-_153521714 1.16 ENST00000368713.3
S100 calcium binding protein A3
chr12_-_54813229 1.13 ENST00000293379.4
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr12_-_49351148 1.13 ENST00000398092.4
ENST00000539611.1
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr2_+_28615669 1.11 ENST00000379619.1
ENST00000264716.4
FOS-like antigen 2
chr1_-_220263096 1.10 ENST00000463953.1
ENST00000354807.3
ENST00000414869.2
ENST00000498237.2
ENST00000498791.2
ENST00000544404.1
ENST00000480959.2
ENST00000322067.7
3'(2'), 5'-bisphosphate nucleotidase 1
chr5_+_143191726 1.09 ENST00000289448.2
histocompatibility (minor) HB-1
chr15_-_77363441 1.06 ENST00000346495.2
ENST00000424443.3
ENST00000561277.1
tetraspanin 3
chr11_-_2924970 0.98 ENST00000533594.1
solute carrier family 22 (organic cation transporter), member 18 antisense
chr11_-_65430251 0.93 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr16_+_57662138 0.90 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
G protein-coupled receptor 56
chr4_-_100356291 0.89 ENST00000476959.1
ENST00000482593.1
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chrX_+_99839799 0.89 ENST00000373031.4
tenomodulin
chr11_-_102826434 0.86 ENST00000340273.4
ENST00000260302.3
matrix metallopeptidase 13 (collagenase 3)
chr1_+_154975258 0.83 ENST00000417934.2
zinc finger and BTB domain containing 7B
chr16_-_72206034 0.81 ENST00000537465.1
ENST00000237353.10
polyamine modulated factor 1 binding protein 1
chr3_-_48632593 0.80 ENST00000454817.1
ENST00000328333.8
collagen, type VII, alpha 1
chr1_+_154975110 0.78 ENST00000535420.1
ENST00000368426.3
zinc finger and BTB domain containing 7B
chr14_+_73525265 0.77 ENST00000525161.1
RNA binding motif protein 25
chr21_+_19617140 0.73 ENST00000299295.2
ENST00000338326.3
chondrolectin
chr6_-_31745085 0.71 ENST00000375686.3
ENST00000447450.1
von Willebrand factor A domain containing 7
chr15_+_77287426 0.70 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
proline-serine-threonine phosphatase interacting protein 1
chr2_+_152214098 0.65 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr17_+_73717516 0.62 ENST00000200181.3
ENST00000339591.3
integrin, beta 4
chr15_+_89631381 0.61 ENST00000352732.5
abhydrolase domain containing 2
chr19_-_44259053 0.60 ENST00000601170.1
SMG9 nonsense mediated mRNA decay factor
chr17_+_73717551 0.58 ENST00000450894.3
integrin, beta 4
chr11_-_102714534 0.57 ENST00000299855.5
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr12_+_58176525 0.54 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
Ts translation elongation factor, mitochondrial
chr19_-_46285736 0.54 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
dystrophia myotonica-protein kinase
chr19_-_54726850 0.53 ENST00000245620.9
ENST00000346401.6
ENST00000424807.1
ENST00000445347.1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
chr15_-_77363375 0.52 ENST00000559494.1
tetraspanin 3
chr3_+_48507621 0.51 ENST00000456089.1
three prime repair exonuclease 1
chr8_-_110988070 0.51 ENST00000524391.1
potassium channel, subfamily V, member 1
chr11_+_394196 0.48 ENST00000331563.2
ENST00000531857.1
plakophilin 3
chr15_+_75498739 0.48 ENST00000565074.1
chromosome 15 open reading frame 39
chr1_-_6662919 0.47 ENST00000377658.4
ENST00000377663.3
kelch-like family member 21
chrX_+_65382381 0.42 ENST00000519389.1
hephaestin
chr15_+_59903975 0.39 ENST00000560585.1
ENST00000396065.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chr18_-_268019 0.36 ENST00000261600.6
THO complex 1
chr12_-_51402984 0.35 ENST00000545993.2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr8_-_108510224 0.34 ENST00000517746.1
ENST00000297450.3
angiopoietin 1
chr2_-_190927447 0.31 ENST00000260950.4
myostatin
chr17_+_72426891 0.31 ENST00000392627.1
G protein-coupled receptor, family C, group 5, member C
chr19_-_39264072 0.22 ENST00000599035.1
ENST00000378626.4
lectin, galactoside-binding, soluble, 7
chr20_+_42187608 0.22 ENST00000373100.1
serum/glucocorticoid regulated kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 25.2 GO:0007296 vitellogenesis(GO:0007296)
4.1 16.3 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
3.3 10.0 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
2.5 7.6 GO:0007518 myoblast fate determination(GO:0007518)
2.4 9.7 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
2.4 12.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
2.3 14.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
2.3 11.5 GO:0015862 uridine transport(GO:0015862)
2.1 6.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
1.9 5.8 GO:1904430 negative regulation of t-circle formation(GO:1904430)
1.9 5.6 GO:1902310 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
1.6 16.4 GO:0035092 sperm chromatin condensation(GO:0035092)
1.4 10.0 GO:0009438 methylglyoxal metabolic process(GO:0009438)
1.3 5.2 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
1.3 3.9 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.3 16.7 GO:0019388 galactose catabolic process(GO:0019388)
1.3 6.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
1.3 25.0 GO:0016540 protein autoprocessing(GO:0016540)
1.2 3.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
1.2 3.6 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
1.2 19.3 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
1.2 13.0 GO:0001731 formation of translation preinitiation complex(GO:0001731)
1.1 6.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.9 4.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.9 6.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.9 4.5 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.9 5.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.8 10.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.7 6.8 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.7 2.0 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.7 9.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.6 6.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.6 3.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.6 7.1 GO:0051665 membrane raft localization(GO:0051665)
0.6 2.4 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.5 15.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.5 1.5 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.5 9.5 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.5 1.5 GO:1903028 positive regulation of opsonization(GO:1903028)
0.5 3.9 GO:0035897 proteolysis in other organism(GO:0035897)
0.4 1.3 GO:2000523 dendritic cell dendrite assembly(GO:0097026) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.4 3.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.4 3.8 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.4 1.6 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.4 3.9 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.4 17.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4 7.6 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.4 3.6 GO:0051660 establishment of centrosome localization(GO:0051660)
0.3 31.3 GO:0070527 platelet aggregation(GO:0070527)
0.3 1.3 GO:0032621 interleukin-18 production(GO:0032621)
0.3 19.7 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.3 7.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.3 1.2 GO:0061743 motor learning(GO:0061743)
0.3 1.2 GO:0071461 cellular response to redox state(GO:0071461)
0.3 3.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 1.5 GO:0006740 NADPH regeneration(GO:0006740)
0.3 10.9 GO:0019430 removal of superoxide radicals(GO:0019430)
0.3 1.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.3 2.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 1.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.3 1.3 GO:0018158 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) protein oxidation(GO:0018158)
0.2 9.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 2.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.2 5.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 1.9 GO:0051014 actin filament severing(GO:0051014)
0.2 28.2 GO:0051225 spindle assembly(GO:0051225)
0.2 0.9 GO:0033590 response to cobalamin(GO:0033590)
0.2 4.8 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.2 3.7 GO:0043248 proteasome assembly(GO:0043248)
0.2 0.9 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 5.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 1.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 4.1 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 15.7 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.2 1.4 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.2 5.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 1.2 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.2 4.6 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.2 1.3 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.2 2.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 3.5 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 11.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 4.1 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.1 0.4 GO:1901977 negative regulation of isotype switching(GO:0045829) negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
0.1 5.2 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 1.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 1.7 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 4.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.9 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 3.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 5.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 1.4 GO:0016180 snRNA processing(GO:0016180)
0.1 0.4 GO:0015692 lead ion transport(GO:0015692)
0.1 0.3 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.1 4.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 6.5 GO:0002062 chondrocyte differentiation(GO:0002062)
0.1 2.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 3.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 3.3 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.1 0.5 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.1 1.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 2.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.5 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.5 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 3.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 4.2 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 1.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.7 GO:0030728 ovulation(GO:0030728)
0.0 0.8 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.5 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 2.6 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 5.7 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 5.0 GO:0007411 axon guidance(GO:0007411)
0.0 0.4 GO:0050892 intestinal absorption(GO:0050892)
0.0 4.1 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.3 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.5 GO:0033565 ESCRT-0 complex(GO:0033565)
3.1 28.2 GO:0070652 HAUS complex(GO:0070652)
2.0 10.0 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
1.7 13.6 GO:0005610 laminin-5 complex(GO:0005610)
1.5 7.6 GO:0045323 interleukin-1 receptor complex(GO:0045323)
1.3 12.1 GO:0005638 lamin filament(GO:0005638)
1.2 3.6 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
1.2 21.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
1.2 5.8 GO:0043564 Ku70:Ku80 complex(GO:0043564)
1.0 19.3 GO:0036020 endolysosome membrane(GO:0036020)
0.8 6.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.8 10.3 GO:0097433 dense body(GO:0097433)
0.8 8.3 GO:0071438 invadopodium membrane(GO:0071438)
0.7 5.2 GO:0031415 NatA complex(GO:0031415)
0.7 5.2 GO:0044294 dendritic growth cone(GO:0044294)
0.4 5.1 GO:0042555 MCM complex(GO:0042555)
0.4 4.7 GO:0009925 basal plasma membrane(GO:0009925)
0.4 1.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.4 5.6 GO:0008290 F-actin capping protein complex(GO:0008290) Flemming body(GO:0090543)
0.4 3.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 11.8 GO:0032420 stereocilium(GO:0032420)
0.3 5.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 7.0 GO:0031105 septin complex(GO:0031105)
0.3 10.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 0.9 GO:0071159 NF-kappaB complex(GO:0071159)
0.3 5.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 1.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 24.5 GO:0042734 presynaptic membrane(GO:0042734)
0.2 1.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 2.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 3.6 GO:0032059 bleb(GO:0032059)
0.2 16.4 GO:0034707 chloride channel complex(GO:0034707)
0.2 2.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 1.4 GO:0032039 integrator complex(GO:0032039)
0.1 1.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.3 GO:0097413 Lewy body(GO:0097413)
0.1 3.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 6.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 20.1 GO:0034399 nuclear periphery(GO:0034399)
0.1 19.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 3.6 GO:0043034 costamere(GO:0043034)
0.1 7.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 6.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.5 GO:0042641 actomyosin(GO:0042641)
0.1 7.4 GO:0005604 basement membrane(GO:0005604)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 7.3 GO:0016324 apical plasma membrane(GO:0016324)
0.1 0.5 GO:0005827 polar microtubule(GO:0005827)
0.1 6.8 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 3.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 10.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 4.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 3.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 12.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 3.5 GO:0000922 spindle pole(GO:0000922)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 7.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.3 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 12.5 GO:0016604 nuclear body(GO:0016604)
0.0 0.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 4.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.8 GO:0005819 spindle(GO:0005819)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.7 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
2.8 8.3 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
2.6 13.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
2.3 16.3 GO:0004849 uridine kinase activity(GO:0004849)
2.1 6.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
1.7 10.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.5 4.5 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
1.4 4.1 GO:0004324 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
1.3 5.3 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
1.3 6.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
1.3 10.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.2 10.9 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.1 7.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
1.0 6.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.0 3.9 GO:0035276 aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.9 3.8 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.9 2.6 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.9 12.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.8 4.9 GO:0003998 acylphosphatase activity(GO:0003998)
0.8 5.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.7 3.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.7 27.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.7 10.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.7 5.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.6 3.9 GO:1990254 keratin filament binding(GO:1990254)
0.6 19.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.6 10.6 GO:0048156 tau protein binding(GO:0048156)
0.6 5.8 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.5 11.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.5 3.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.5 2.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.5 2.4 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.4 5.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.3 16.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.3 1.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.3 1.5 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.3 13.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.3 13.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 3.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 1.4 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 1.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 2.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 1.4 GO:0038132 neuregulin binding(GO:0038132)
0.2 8.3 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.2 1.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 5.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2 6.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 3.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 2.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 4.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 4.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 1.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 6.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 8.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 11.5 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1 1.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 1.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 33.4 GO:0003924 GTPase activity(GO:0003924)
0.1 5.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.1 GO:0008252 nucleotidase activity(GO:0008252)
0.1 1.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 3.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 2.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.4 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 13.7 GO:0000287 magnesium ion binding(GO:0000287)
0.1 3.6 GO:0043621 protein self-association(GO:0043621)
0.1 4.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 2.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 31.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.5 GO:0043531 ADP binding(GO:0043531)
0.0 1.4 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 9.4 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 3.8 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 5.3 GO:0051015 actin filament binding(GO:0051015)
0.0 3.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 5.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 2.2 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 3.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.5 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 52.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.5 13.1 PID ARF 3PATHWAY Arf1 pathway
0.4 14.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 7.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 8.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.3 25.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.3 6.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.3 7.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.3 22.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 10.9 PID IL1 PATHWAY IL1-mediated signaling events
0.2 3.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 11.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 17.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 13.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 13.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 5.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 6.5 PID RAS PATHWAY Regulation of Ras family activation
0.2 6.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 8.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 5.7 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 13.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 15.1 PID E2F PATHWAY E2F transcription factor network
0.1 1.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 3.8 PID TNF PATHWAY TNF receptor signaling pathway
0.1 5.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 6.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 3.3 PID PLK1 PATHWAY PLK1 signaling events
0.1 10.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 2.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 4.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 18.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.6 7.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.5 9.9 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.5 13.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 13.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.5 3.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.5 16.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.4 9.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.4 18.7 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.4 5.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 5.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.3 11.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.3 5.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 6.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.3 3.9 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.3 6.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.3 7.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.3 8.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.3 11.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 5.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 1.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 3.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.2 14.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2 2.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 4.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 3.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 13.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 10.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 6.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 3.4 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.2 5.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 14.4 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 3.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 8.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 22.6 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.1 5.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.9 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 4.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 13.0 REACTOME TRANSLATION Genes involved in Translation
0.0 1.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.1 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins