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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GGAAGAC

Z-value: 0.54

Motif logo

logo of

miRNA associated with seed GGAAGAC

NamemiRBASE accession
hsa-miR-7-5p
MIMAT0000252

Activity profile of GGAAGAC motif

Sorted Z-values of GGAAGAC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_10979750 8.09 ENST00000339600.5
NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr5_-_111093406 7.05 ENST00000379671.3
NREP
neuronal regeneration related protein
chr2_-_161350305 6.78 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr3_-_12705600 6.29 ENST00000542177.1
ENST00000442415.2
ENST00000251849.4
RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
chr20_+_35202909 6.17 ENST00000558530.1
ENST00000558028.1
ENST00000560025.1
TGIF2-C20orf24
TGIF2
TGIF2-C20orf24 readthrough
TGFB-induced factor homeobox 2
chr1_+_113161778 6.06 ENST00000263168.3
CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr2_-_131850951 5.37 ENST00000409185.1
ENST00000389915.3
FAM168B
family with sequence similarity 168, member B
chr12_-_106641728 5.30 ENST00000378026.4
CKAP4
cytoskeleton-associated protein 4
chr5_+_31532373 5.03 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
C5orf22
chromosome 5 open reading frame 22
chr18_-_9614515 4.93 ENST00000400556.3
ENST00000400555.3
PPP4R1
protein phosphatase 4, regulatory subunit 1
chr8_+_26435359 4.70 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr2_-_62115725 4.65 ENST00000538252.1
ENST00000544079.1
ENST00000394440.3
CCT4
chaperonin containing TCP1, subunit 4 (delta)
chr3_-_195808952 4.50 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
TFRC
transferrin receptor
chr3_+_141106643 4.45 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr14_-_90085458 4.43 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr6_-_16761678 4.43 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr15_+_57210818 4.37 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12
transcription factor 12
chr10_+_70883908 4.35 ENST00000263559.6
ENST00000395098.1
ENST00000546041.1
ENST00000541711.1
VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr19_-_47616992 4.28 ENST00000253048.5
ZC3H4
zinc finger CCCH-type containing 4
chr5_-_133340326 4.06 ENST00000425992.1
ENST00000395044.3
ENST00000395047.2
VDAC1
voltage-dependent anion channel 1
chr3_-_149688896 3.71 ENST00000239940.7
PFN2
profilin 2
chr5_+_177019159 3.67 ENST00000332598.6
TMED9
transmembrane emp24 protein transport domain containing 9
chr3_-_125313934 3.67 ENST00000296220.5
OSBPL11
oxysterol binding protein-like 11
chr3_-_18466787 3.60 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr1_+_206557366 3.56 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr4_-_99851766 3.55 ENST00000450253.2
EIF4E
eukaryotic translation initiation factor 4E
chr12_-_46766577 3.53 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr14_+_70078303 3.51 ENST00000342745.4
KIAA0247
KIAA0247
chr1_-_114355083 3.34 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chr17_-_48474828 3.29 ENST00000576448.1
ENST00000225972.7
LRRC59
leucine rich repeat containing 59
chr2_+_178257372 3.24 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr4_-_90758227 3.15 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr13_-_110438914 3.15 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr4_-_76598296 2.99 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr8_-_28243934 2.93 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395
zinc finger protein 395
chr14_+_19553365 2.85 ENST00000409832.3
POTEG
POTE ankyrin domain family, member G
chrX_+_49028265 2.77 ENST00000376322.3
ENST00000376327.5
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr3_+_196466710 2.72 ENST00000327134.3
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr5_+_137688285 2.66 ENST00000314358.5
KDM3B
lysine (K)-specific demethylase 3B
chr8_+_107670064 2.66 ENST00000312046.6
OXR1
oxidation resistance 1
chr6_-_24721054 2.64 ENST00000378119.4
C6orf62
chromosome 6 open reading frame 62
chr3_+_126707437 2.59 ENST00000393409.2
ENST00000251772.4
PLXNA1
plexin A1
chr17_+_38375574 2.56 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2
WAS/WASL interacting protein family, member 2
chr1_-_95392635 2.56 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr20_+_35234137 2.50 ENST00000344795.3
ENST00000373852.5
C20orf24
chromosome 20 open reading frame 24
chr1_-_205719295 2.49 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr1_-_109584608 2.46 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47
WD repeat domain 47
chr14_-_20020272 2.44 ENST00000551509.1
POTEM
POTE ankyrin domain family, member M
chr10_-_112064665 2.42 ENST00000369603.5
SMNDC1
survival motor neuron domain containing 1
chr14_+_23340822 2.37 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr3_-_33686743 2.36 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr11_-_46142948 2.29 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr2_+_7057523 2.27 ENST00000320892.6
RNF144A
ring finger protein 144A
chr3_-_52312636 2.17 ENST00000296490.3
WDR82
WD repeat domain 82
chr2_-_227664474 2.13 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr10_-_88281494 2.07 ENST00000298767.5
WAPAL
wings apart-like homolog (Drosophila)
chr3_-_57583130 2.01 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr17_-_79885576 1.87 ENST00000574686.1
ENST00000357736.4
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr11_-_70507901 1.76 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr4_+_129730779 1.74 ENST00000226319.6
PHF17
jade family PHD finger 1
chr8_+_59323823 1.69 ENST00000399598.2
UBXN2B
UBX domain protein 2B
chr12_-_58240470 1.67 ENST00000548823.1
ENST00000398073.2
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr7_-_32931387 1.66 ENST00000304056.4
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr2_-_220041617 1.61 ENST00000451647.1
ENST00000360507.5
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr11_+_9406169 1.54 ENST00000379719.3
ENST00000527431.1
IPO7
importin 7
chr2_-_97535708 1.53 ENST00000305476.5
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr3_-_125094093 1.46 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
ZNF148
zinc finger protein 148
chr11_-_115375107 1.43 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chrX_+_40944871 1.36 ENST00000378308.2
ENST00000324545.8
USP9X
ubiquitin specific peptidase 9, X-linked
chr3_+_30648066 1.18 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr1_+_229440129 1.16 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr10_+_43278217 1.16 ENST00000374518.5
BMS1
BMS1 ribosome biogenesis factor
chrX_+_70752917 1.13 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr11_-_31839488 1.13 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
PAX6
paired box 6
chr8_-_145013711 1.09 ENST00000345136.3
PLEC
plectin
chr2_+_220042933 1.08 ENST00000430297.2
FAM134A
family with sequence similarity 134, member A
chr3_+_112280857 1.06 ENST00000492406.1
ENST00000468642.1
SLC35A5
solute carrier family 35, member A5
chr16_-_18812746 1.03 ENST00000546206.2
ENST00000562819.1
ENST00000562234.2
ENST00000304414.7
ENST00000567078.2
ARL6IP1
RP11-1035H13.3
ADP-ribosylation factor-like 6 interacting protein 1
Uncharacterized protein
chr5_+_17217669 1.02 ENST00000322611.3
BASP1
brain abundant, membrane attached signal protein 1
chrX_-_148586804 1.01 ENST00000428056.2
ENST00000340855.6
ENST00000370441.4
ENST00000370443.4
IDS
iduronate 2-sulfatase
chr3_+_45636219 1.00 ENST00000273317.4
LIMD1
LIM domains containing 1
chr7_+_7606497 1.00 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
MIOS
missing oocyte, meiosis regulator, homolog (Drosophila)
chr1_+_66797687 0.92 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr5_+_154238096 0.88 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
CNOT8
CCR4-NOT transcription complex, subunit 8
chr6_+_111195973 0.85 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr17_+_40985407 0.85 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr3_+_142720366 0.84 ENST00000493782.1
ENST00000397933.2
ENST00000473835.2
ENST00000493598.2
U2SURP
U2 snRNP-associated SURP domain containing
chr1_+_229406847 0.82 ENST00000366690.4
RAB4A
RAB4A, member RAS oncogene family
chr4_-_103748880 0.82 ENST00000453744.2
ENST00000349311.8
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr2_-_242212227 0.82 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
HDLBP
high density lipoprotein binding protein
chr12_+_65563329 0.79 ENST00000308330.2
LEMD3
LEM domain containing 3
chr4_+_39699664 0.76 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
UBE2K
ubiquitin-conjugating enzyme E2K
chr14_-_70883708 0.76 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr1_-_40157345 0.76 ENST00000372844.3
HPCAL4
hippocalcin like 4
chr2_+_201676256 0.74 ENST00000452206.1
ENST00000410110.2
ENST00000409600.1
BZW1
basic leucine zipper and W2 domains 1
chr16_-_12009735 0.73 ENST00000439887.2
ENST00000434724.2
GSPT1
G1 to S phase transition 1
chr9_-_123555655 0.71 ENST00000340778.5
ENST00000453291.1
ENST00000608872.1
FBXW2
F-box and WD repeat domain containing 2
chr16_+_69345243 0.71 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr8_+_42249418 0.70 ENST00000521158.1
ENST00000022615.4
VDAC3
voltage-dependent anion channel 3
chr14_+_73603126 0.69 ENST00000557356.1
ENST00000556864.1
ENST00000556533.1
ENST00000556951.1
ENST00000557293.1
ENST00000553719.1
ENST00000553599.1
ENST00000556011.1
ENST00000394157.3
ENST00000357710.4
ENST00000324501.5
ENST00000560005.2
ENST00000555254.1
ENST00000261970.3
ENST00000344094.3
ENST00000554131.1
ENST00000557037.1
PSEN1
presenilin 1
chr9_-_110251836 0.69 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr1_-_70671216 0.67 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr6_+_13615554 0.67 ENST00000451315.2
NOL7
nucleolar protein 7, 27kDa
chr18_-_53255766 0.66 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr15_-_65809581 0.65 ENST00000341861.5
DPP8
dipeptidyl-peptidase 8
chr20_-_30310336 0.64 ENST00000434194.1
ENST00000376062.2
BCL2L1
BCL2-like 1
chr17_-_4269768 0.64 ENST00000396981.2
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr16_+_28962128 0.64 ENST00000564978.1
ENST00000320805.4
NFATC2IP
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
chr10_+_80828774 0.63 ENST00000334512.5
ZMIZ1
zinc finger, MIZ-type containing 1
chr10_+_81107216 0.62 ENST00000394579.3
ENST00000225174.3
PPIF
peptidylprolyl isomerase F
chr7_+_139044621 0.62 ENST00000354926.4
C7orf55-LUC7L2
C7orf55-LUC7L2 readthrough
chr12_+_56367697 0.62 ENST00000553116.1
ENST00000360299.5
ENST00000548068.1
ENST00000549915.1
ENST00000551459.1
ENST00000448789.2
RAB5B
RAB5B, member RAS oncogene family
chr6_-_134639180 0.61 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr3_-_72496035 0.60 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr3_-_69435224 0.57 ENST00000398540.3
FRMD4B
FERM domain containing 4B
chr9_+_128509624 0.53 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chr7_+_128379346 0.53 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr2_-_166651191 0.51 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr1_+_87170247 0.50 ENST00000370558.4
SH3GLB1
SH3-domain GRB2-like endophilin B1
chr10_+_74033672 0.49 ENST00000307365.3
DDIT4
DNA-damage-inducible transcript 4
chr5_+_145826867 0.48 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr1_+_36348790 0.47 ENST00000373204.4
AGO1
argonaute RISC catalytic component 1
chr15_+_77712993 0.46 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
HMG20A
high mobility group 20A
chr1_-_115053781 0.44 ENST00000358465.2
ENST00000369543.2
TRIM33
tripartite motif containing 33
chr3_+_180630090 0.39 ENST00000357559.4
ENST00000305586.7
FXR1
fragile X mental retardation, autosomal homolog 1
chr17_-_1465924 0.38 ENST00000573231.1
ENST00000576722.1
ENST00000576761.1
ENST00000576010.2
ENST00000313486.7
ENST00000539476.1
PITPNA
phosphatidylinositol transfer protein, alpha
chr3_-_150264272 0.37 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr18_-_51751132 0.36 ENST00000256429.3
MBD2
methyl-CpG binding domain protein 2
chr3_-_195270162 0.36 ENST00000438848.1
ENST00000328432.3
PPP1R2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr14_+_23790655 0.34 ENST00000397276.2
PABPN1
poly(A) binding protein, nuclear 1
chr11_+_107879459 0.33 ENST00000393094.2
CUL5
cullin 5
chr17_+_28804380 0.32 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
GOSR1
golgi SNAP receptor complex member 1
chr17_+_68165657 0.29 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr15_+_72766651 0.29 ENST00000379887.4
ARIH1
ariadne RBR E3 ubiquitin protein ligase 1
chr9_-_128469456 0.27 ENST00000427078.1
ENST00000373496.3
ENST00000433483.1
ENST00000350766.3
ENST00000373503.3
ENST00000373511.2
ENST00000394060.3
ENST00000265960.3
ENST00000394063.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr1_-_244013384 0.26 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr11_+_85956182 0.26 ENST00000327320.4
ENST00000351625.6
ENST00000534595.1
EED
embryonic ectoderm development
chrX_+_108780062 0.25 ENST00000372106.1
NXT2
nuclear transport factor 2-like export factor 2
chr1_+_193091080 0.24 ENST00000367435.3
CDC73
cell division cycle 73
chr9_-_14314066 0.23 ENST00000397575.3
NFIB
nuclear factor I/B
chr3_-_133969437 0.23 ENST00000460933.1
ENST00000296084.4
RYK
receptor-like tyrosine kinase
chr16_-_74640986 0.23 ENST00000422840.2
ENST00000565260.1
ENST00000447066.2
ENST00000205061.5
GLG1
golgi glycoprotein 1
chr11_-_85780086 0.23 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr12_-_14133053 0.23 ENST00000609686.1
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr2_+_234263120 0.21 ENST00000264057.2
ENST00000427930.1
DGKD
diacylglycerol kinase, delta 130kDa
chr7_+_106809406 0.20 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1
HMG-box transcription factor 1
chr16_+_85646763 0.19 ENST00000411612.1
ENST00000253458.7
GSE1
Gse1 coiled-coil protein
chr8_+_87354945 0.18 ENST00000517970.1
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr16_+_16043406 0.18 ENST00000399410.3
ENST00000399408.2
ENST00000346370.5
ENST00000351154.5
ENST00000345148.5
ENST00000349029.5
ABCC1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
chr15_+_68346501 0.17 ENST00000249636.6
PIAS1
protein inhibitor of activated STAT, 1
chr7_-_75368248 0.17 ENST00000434438.2
ENST00000336926.6
HIP1
huntingtin interacting protein 1
chr1_-_47069955 0.15 ENST00000341183.5
ENST00000496619.1
MKNK1
MAP kinase interacting serine/threonine kinase 1
chr1_-_85156216 0.14 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr10_-_98945677 0.13 ENST00000266058.4
ENST00000371041.3
SLIT1
slit homolog 1 (Drosophila)
chr1_+_224301787 0.12 ENST00000366862.5
ENST00000424254.2
FBXO28
F-box protein 28
chr3_-_121468602 0.11 ENST00000340645.5
GOLGB1
golgin B1
chr2_-_70995307 0.10 ENST00000264436.4
ENST00000355733.3
ENST00000447731.2
ENST00000430656.1
ENST00000413157.2
ADD2
adducin 2 (beta)
chr3_+_11314099 0.10 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
ATG7
autophagy related 7
chr17_-_42143963 0.09 ENST00000585388.1
ENST00000293406.3
LSM12
LSM12 homolog (S. cerevisiae)
chr20_-_16554078 0.09 ENST00000354981.2
ENST00000355755.3
ENST00000378003.2
ENST00000408042.1
KIF16B
kinesin family member 16B
chr5_+_71403061 0.08 ENST00000512974.1
ENST00000296755.7
MAP1B
microtubule-associated protein 1B
chr7_+_148936732 0.08 ENST00000335870.2
ZNF212
zinc finger protein 212
chr12_+_58166431 0.08 ENST00000333012.5
METTL21B
methyltransferase like 21B
chr17_-_56406117 0.07 ENST00000268893.6
ENST00000355701.3
BZRAP1
benzodiazepine receptor (peripheral) associated protein 1
chr14_+_75469606 0.07 ENST00000266126.5
EIF2B2
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
chr1_+_206643787 0.07 ENST00000367120.3
IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr17_+_57970469 0.07 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr3_-_138553594 0.06 ENST00000477593.1
ENST00000483968.1
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr1_+_184356188 0.03 ENST00000235307.6
C1orf21
chromosome 1 open reading frame 21
chr22_+_40573921 0.02 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr8_+_23386305 0.02 ENST00000519973.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr11_-_75062730 0.02 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr17_+_5390220 0.01 ENST00000381165.3
MIS12
MIS12 kinetochore complex component
chr3_-_88108192 0.01 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr5_+_149887672 0.01 ENST00000261797.6
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

Network of associatons between targets according to the STRING database.

First level regulatory network of GGAAGAC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.9 3.7 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.7 2.7 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.6 3.2 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.6 2.5 GO:0019046 release from viral latency(GO:0019046)
0.6 3.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.6 3.5 GO:0032328 alanine transport(GO:0032328)
0.5 5.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.5 4.6 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.4 6.3 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.4 0.8 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.4 1.2 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.4 8.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 1.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4 1.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.4 3.6 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.3 6.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.3 0.6 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.3 3.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 2.7 GO:0072718 response to cisplatin(GO:0072718)
0.3 2.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 0.9 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 2.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.7 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 0.7 GO:0090611 mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.2 0.7 GO:0071409 negative regulation of muscle hyperplasia(GO:0014740) cellular response to cycloheximide(GO:0071409)
0.2 1.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 3.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 4.3 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.2 1.0 GO:2001076 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.2 4.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.2 6.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 4.1 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.2 2.0 GO:0031584 activation of phospholipase D activity(GO:0031584) apical protein localization(GO:0045176)
0.2 4.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 3.0 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253) stress granule assembly(GO:0034063)
0.2 1.0 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 2.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 2.0 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.6 GO:0046898 response to cycloheximide(GO:0046898)
0.1 1.0 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 2.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.5 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 1.0 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.7 GO:0015853 adenine transport(GO:0015853)
0.1 0.3 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.8 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.1 0.5 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 1.2 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 4.1 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.1 0.6 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.2 GO:0061643 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.1 1.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 1.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 1.8 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.9 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.8 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 1.7 GO:0042330 chemotaxis(GO:0006935) taxis(GO:0042330)
0.0 6.1 GO:0048675 axon extension(GO:0048675)
0.0 0.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 1.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0090296 late nucleophagy(GO:0044805) regulation of mitochondrial DNA replication(GO:0090296) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) single-organism membrane invagination(GO:1902534)
0.0 0.2 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 1.0 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.6 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.4 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.4 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 1.9 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 1.5 GO:0021762 substantia nigra development(GO:0021762)
0.0 10.0 GO:0006260 DNA replication(GO:0006260)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.7 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 2.6 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.2 GO:1903318 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 1.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.7 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
0.0 0.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 5.0 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.6 GO:0016925 protein sumoylation(GO:0016925)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0030289 protein phosphatase 4 complex(GO:0030289)
1.4 4.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.9 4.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.9 6.1 GO:0071203 WASH complex(GO:0071203)
0.6 8.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.4 2.1 GO:0005899 insulin receptor complex(GO:0005899)
0.4 4.6 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.3 4.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 3.5 GO:0033391 chromatoid body(GO:0033391)
0.3 3.6 GO:0044327 dendritic spine head(GO:0044327)
0.3 5.3 GO:0042599 lamellar body(GO:0042599)
0.2 0.7 GO:0018444 translation release factor complex(GO:0018444)
0.2 2.4 GO:0045180 basal cortex(GO:0045180)
0.2 2.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 6.3 GO:0031143 pseudopodium(GO:0031143)
0.2 2.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 4.8 GO:0046930 pore complex(GO:0046930)
0.2 1.0 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 0.8 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.8 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.3 GO:0005883 neurofilament(GO:0005883)
0.1 3.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 3.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.5 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 3.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.1 3.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 2.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.8 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 3.7 GO:0043195 terminal bouton(GO:0043195)
0.0 2.3 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.8 GO:0032433 filopodium tip(GO:0032433)
0.0 2.7 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 1.2 GO:0030686 90S preribosome(GO:0030686)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.5 GO:0005903 brush border(GO:0005903)
0.0 3.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 3.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 4.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 7.0 GO:0005874 microtubule(GO:0005874)
0.0 2.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.1 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
1.5 4.5 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.9 4.4 GO:0034046 poly(G) binding(GO:0034046)
0.6 3.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.5 4.8 GO:0015288 porin activity(GO:0015288)
0.4 3.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.4 1.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3 1.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 1.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.3 8.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 1.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 6.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 4.4 GO:0035497 cAMP response element binding(GO:0035497)
0.2 4.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 1.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 0.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 5.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.2 2.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 2.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 4.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.7 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 2.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 2.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 2.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.5 GO:0038191 neuropilin binding(GO:0038191)
0.1 2.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 3.7 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.8 GO:0019956 chemokine binding(GO:0019956)
0.1 1.1 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1 1.8 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.6 GO:0051434 BH3 domain binding(GO:0051434)
0.1 3.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.6 GO:0031386 protein tag(GO:0031386)
0.1 5.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 6.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.4 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 1.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 3.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 3.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 0.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 2.2 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 9.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 2.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 5.5 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 6.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 3.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 5.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.7 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 3.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 4.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.6 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.3 7.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 6.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 10.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 3.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 8.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 5.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 4.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 3.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 5.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 3.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 8.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 4.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 4.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 1.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 3.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 2.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 3.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling