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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GGAAUGU

Z-value: 1.73

Motif logo

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miRNA associated with seed GGAAUGU

NamemiRBASE accession
hsa-miR-1-3p
MIMAT0000416
hsa-miR-206
MIMAT0000462
hsa-miR-613
MIMAT0003281

Activity profile of GGAAUGU motif

Sorted Z-values of GGAAUGU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_109125285 47.63 ENST00000552871.1
ENST00000261401.3
CORO1C
coronin, actin binding protein, 1C
chr1_-_159893507 37.88 ENST00000368096.1
TAGLN2
transgelin 2
chr8_-_103876965 34.49 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr1_+_26606608 32.88 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr6_+_47445467 32.74 ENST00000359314.5
CD2AP
CD2-associated protein
chr15_-_60690163 30.53 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2
annexin A2
chr15_+_65822756 30.30 ENST00000562901.1
ENST00000261875.5
ENST00000442729.2
ENST00000565299.1
ENST00000568793.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr1_+_10459111 29.99 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
PGD
phosphogluconate dehydrogenase
chr17_+_37026106 29.35 ENST00000318008.6
LASP1
LIM and SH3 protein 1
chr1_+_113161778 29.29 ENST00000263168.3
CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr12_+_69004619 29.21 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B
RAP1B, member of RAS oncogene family
chr12_+_104324112 28.26 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr1_-_154600421 27.10 ENST00000368471.3
ENST00000292205.5
ADAR
adenosine deaminase, RNA-specific
chr14_+_20937538 26.36 ENST00000361505.5
ENST00000553591.1
PNP
purine nucleoside phosphorylase
chr3_+_171758344 25.62 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr22_-_39096661 25.40 ENST00000216039.5
JOSD1
Josephin domain containing 1
chr3_-_195163803 24.89 ENST00000326793.6
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr14_+_51706886 24.31 ENST00000457354.2
TMX1
thioredoxin-related transmembrane protein 1
chr2_+_69969106 23.97 ENST00000409920.1
ENST00000394295.4
ENST00000536030.1
ANXA4
annexin A4
chr5_+_138629417 23.85 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
MATR3
matrin 3
chrX_-_153775426 23.60 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr17_+_49243639 22.86 ENST00000512737.1
ENST00000503064.1
NME1-NME2
NME1-NME2 readthrough
chr1_-_245027833 22.74 ENST00000444376.2
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr9_+_100745615 22.69 ENST00000339399.4
ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr5_+_151151471 22.65 ENST00000394123.3
ENST00000543466.1
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr8_-_101965146 22.23 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr5_+_122110691 22.20 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2
sorting nexin 2
chr5_+_86564739 21.81 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr12_-_120907459 21.80 ENST00000229390.3
SRSF9
serine/arginine-rich splicing factor 9
chr18_+_29671812 21.70 ENST00000261593.3
ENST00000578914.1
RNF138
ring finger protein 138, E3 ubiquitin protein ligase
chr11_+_118230287 21.21 ENST00000252108.3
ENST00000431736.2
UBE4A
ubiquitination factor E4A
chr14_+_56046914 21.07 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1
kinectin 1 (kinesin receptor)
chr2_-_96874553 20.90 ENST00000337288.5
ENST00000443962.1
STARD7
StAR-related lipid transfer (START) domain containing 7
chr10_+_104535994 20.59 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr1_-_89357179 20.44 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
GTF2B
general transcription factor IIB
chr17_+_57784826 20.20 ENST00000262291.4
VMP1
vacuole membrane protein 1
chr3_+_127771212 19.83 ENST00000243253.3
ENST00000481210.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr6_+_114178512 19.57 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chrX_+_123095155 19.11 ENST00000371160.1
ENST00000435103.1
STAG2
stromal antigen 2
chr12_-_46766577 19.06 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr8_+_59465728 19.06 ENST00000260130.4
ENST00000422546.2
ENST00000447182.2
ENST00000413219.2
ENST00000424270.2
ENST00000523483.1
ENST00000520168.1
SDCBP
syndecan binding protein (syntenin)
chr8_+_20054878 18.99 ENST00000276390.2
ENST00000519667.1
ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr3_-_42846021 18.83 ENST00000321331.7
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr1_-_150947343 18.72 ENST00000271688.6
ENST00000368954.5
CERS2
ceramide synthase 2
chr3_-_167452614 18.67 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
PDCD10
programmed cell death 10
chr5_+_74632993 18.57 ENST00000287936.4
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr12_-_58146048 18.44 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
CDK4
cyclin-dependent kinase 4
chr4_-_99851766 18.43 ENST00000450253.2
EIF4E
eukaryotic translation initiation factor 4E
chr6_-_86352642 18.42 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr3_-_72496035 18.33 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr14_+_19553365 18.23 ENST00000409832.3
POTEG
POTE ankyrin domain family, member G
chr11_+_86748863 18.21 ENST00000340353.7
TMEM135
transmembrane protein 135
chr18_+_3451646 17.94 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chrX_-_20159934 17.86 ENST00000379593.1
ENST00000379607.5
EIF1AX
eukaryotic translation initiation factor 1A, X-linked
chr4_-_24586140 17.82 ENST00000336812.4
DHX15
DEAH (Asp-Glu-Ala-His) box helicase 15
chr10_+_99185917 17.66 ENST00000334828.5
PGAM1
phosphoglycerate mutase 1 (brain)
chr1_-_95392635 17.44 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr12_-_76953284 17.20 ENST00000547544.1
ENST00000393249.2
OSBPL8
oxysterol binding protein-like 8
chr1_-_150208291 17.14 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr19_+_16187085 16.46 ENST00000300933.4
TPM4
tropomyosin 4
chr2_-_131850951 16.44 ENST00000409185.1
ENST00000389915.3
FAM168B
family with sequence similarity 168, member B
chr3_+_113465866 16.27 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr11_+_46354455 16.18 ENST00000343674.6
DGKZ
diacylglycerol kinase, zeta
chr11_+_34073195 16.10 ENST00000341394.4
CAPRIN1
cell cycle associated protein 1
chr15_-_64455404 15.95 ENST00000300026.3
PPIB
peptidylprolyl isomerase B (cyclophilin B)
chr10_+_93558069 15.83 ENST00000371627.4
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr2_-_131267239 15.63 ENST00000451531.2
POTEI
POTE ankyrin domain family, member I
chr7_-_87849340 15.44 ENST00000419179.1
ENST00000265729.2
SRI
sorcin
chr20_-_45984401 15.38 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr1_+_112162381 15.34 ENST00000433097.1
ENST00000369709.3
ENST00000436150.2
RAP1A
RAP1A, member of RAS oncogene family
chr20_-_52210368 15.30 ENST00000371471.2
ZNF217
zinc finger protein 217
chr11_-_76091986 15.29 ENST00000260045.3
PRKRIR
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr12_-_49351303 15.09 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr14_-_20020272 15.04 ENST00000551509.1
POTEM
POTE ankyrin domain family, member M
chr4_-_76598296 15.03 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr17_-_62502639 14.88 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr3_-_53290016 14.78 ENST00000423525.2
ENST00000423516.1
ENST00000296289.6
ENST00000462138.1
TKT
transketolase
chr17_+_57697216 14.72 ENST00000393043.1
ENST00000269122.3
CLTC
clathrin, heavy chain (Hc)
chr2_-_26101374 14.64 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr7_-_86849025 14.57 ENST00000257637.3
TMEM243
transmembrane protein 243, mitochondrial
chr9_-_36276966 14.57 ENST00000543356.2
ENST00000396594.3
GNE
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr1_-_78148324 14.05 ENST00000370801.3
ENST00000433749.1
ZZZ3
zinc finger, ZZ-type containing 3
chrX_+_41192595 14.04 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr12_-_44200052 14.01 ENST00000548315.1
ENST00000552521.1
ENST00000546662.1
ENST00000548403.1
ENST00000546506.1
TWF1
twinfilin actin-binding protein 1
chr19_+_56152262 13.92 ENST00000325333.5
ENST00000590190.1
ZNF580
zinc finger protein 580
chr20_-_36156125 13.80 ENST00000397135.1
ENST00000397137.1
BLCAP
bladder cancer associated protein
chr2_-_9770706 13.72 ENST00000381844.4
YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
chr4_+_41992489 13.57 ENST00000264451.7
SLC30A9
solute carrier family 30 (zinc transporter), member 9
chr5_+_61602055 13.55 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr19_+_7459998 13.42 ENST00000319670.9
ENST00000599752.1
ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr12_-_118797475 13.39 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr4_-_111119804 13.31 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr7_-_6523755 13.28 ENST00000436575.1
ENST00000258739.4
DAGLB
KDELR2
diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr5_-_172756506 13.15 ENST00000265087.4
STC2
stanniocalcin 2
chr7_+_100797678 13.00 ENST00000337619.5
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr1_-_35658736 12.83 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr11_+_842808 12.81 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
TSPAN4
tetraspanin 4
chr2_+_36582857 12.80 ENST00000280527.2
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr2_+_242255275 12.74 ENST00000391971.2
SEPT2
septin 2
chr7_-_105925558 12.71 ENST00000222553.3
NAMPT
nicotinamide phosphoribosyltransferase
chr17_+_30264014 12.68 ENST00000322652.5
ENST00000580398.1
SUZ12
SUZ12 polycomb repressive complex 2 subunit
chr1_-_114355083 12.56 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chr6_-_79944336 12.46 ENST00000344726.5
ENST00000275036.7
HMGN3
high mobility group nucleosomal binding domain 3
chr3_-_134093395 12.30 ENST00000249883.5
AMOTL2
angiomotin like 2
chr16_-_28222797 12.24 ENST00000569951.1
ENST00000565698.1
XPO6
exportin 6
chr12_-_102224704 12.15 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr2_-_169104651 12.09 ENST00000355999.4
STK39
serine threonine kinase 39
chr15_-_101792137 11.94 ENST00000254190.3
CHSY1
chondroitin sulfate synthase 1
chr8_-_49833978 11.60 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr4_-_10118469 11.44 ENST00000499869.2
WDR1
WD repeat domain 1
chr3_+_169684553 11.37 ENST00000337002.4
ENST00000480708.1
SEC62
SEC62 homolog (S. cerevisiae)
chr10_+_5454505 11.21 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr14_+_90863327 11.08 ENST00000356978.4
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr1_+_206557366 10.92 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr17_-_53499310 10.91 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr3_+_169940153 10.80 ENST00000295797.4
PRKCI
protein kinase C, iota
chr3_-_57583130 10.78 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr1_-_39325431 10.77 ENST00000373001.3
RRAGC
Ras-related GTP binding C
chr2_+_99225018 10.70 ENST00000357765.2
ENST00000409975.1
UNC50
unc-50 homolog (C. elegans)
chr6_-_100016527 10.63 ENST00000523985.1
ENST00000518714.1
ENST00000520371.1
CCNC
cyclin C
chr9_-_36400213 10.59 ENST00000259605.6
ENST00000353739.4
RNF38
ring finger protein 38
chr10_-_126849068 10.57 ENST00000494626.2
ENST00000337195.5
CTBP2
C-terminal binding protein 2
chr3_-_149688896 10.56 ENST00000239940.7
PFN2
profilin 2
chr17_+_38375574 10.55 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2
WAS/WASL interacting protein family, member 2
chr2_+_120517174 10.51 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr7_+_98923505 10.48 ENST00000432884.2
ENST00000262942.5
ARPC1A
actin related protein 2/3 complex, subunit 1A, 41kDa
chr6_-_53409890 10.42 ENST00000229416.6
GCLC
glutamate-cysteine ligase, catalytic subunit
chr12_-_31945172 10.35 ENST00000340398.3
H3F3C
H3 histone, family 3C
chr11_-_796197 10.22 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr5_-_32174369 9.67 ENST00000265070.6
GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr3_-_47823298 9.62 ENST00000254480.5
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr22_-_39268308 9.61 ENST00000407418.3
CBX6
chromobox homolog 6
chr11_+_118443098 9.36 ENST00000392859.3
ENST00000359415.4
ENST00000534182.2
ENST00000264028.4
ARCN1
archain 1
chr17_+_28804380 9.32 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
GOSR1
golgi SNAP receptor complex member 1
chr18_+_9913977 9.28 ENST00000400000.2
ENST00000340541.4
VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr3_-_197025447 9.26 ENST00000346964.2
ENST00000357674.4
ENST00000314062.3
ENST00000448528.2
ENST00000419553.1
DLG1
discs, large homolog 1 (Drosophila)
chr7_-_144435985 9.11 ENST00000549981.1
TPK1
thiamin pyrophosphokinase 1
chr2_+_232573208 9.10 ENST00000409115.3
PTMA
prothymosin, alpha
chr9_-_86595503 8.97 ENST00000376281.4
ENST00000376264.2
HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr7_-_5570229 8.97 ENST00000331789.5
ACTB
actin, beta
chr2_-_47403642 8.91 ENST00000456319.1
ENST00000409563.1
ENST00000272298.7
CALM2
calmodulin 2 (phosphorylase kinase, delta)
chr19_+_36706024 8.83 ENST00000443387.2
ZNF146
zinc finger protein 146
chr1_+_155179012 8.68 ENST00000609421.1
MTX1
metaxin 1
chr19_-_18392422 8.67 ENST00000252818.3
JUND
jun D proto-oncogene
chr5_+_112312416 8.55 ENST00000389063.2
DCP2
decapping mRNA 2
chr3_-_100120223 8.39 ENST00000284320.5
TOMM70A
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
chr16_+_69458428 8.36 ENST00000512062.1
ENST00000307892.8
CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
chr19_+_41725088 8.33 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr2_+_178077477 8.30 ENST00000411529.2
ENST00000435711.1
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3
chr1_+_84543734 8.04 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr17_+_2496971 8.01 ENST00000397195.5
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr6_+_15246501 7.93 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr15_-_78591912 7.86 ENST00000560569.1
ENST00000558459.1
ENST00000558311.1
WDR61
WD repeat domain 61
chr8_-_37756972 7.83 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr1_+_93913713 7.82 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr1_-_78225482 7.71 ENST00000524778.1
ENST00000370794.3
ENST00000370793.1
ENST00000370792.3
USP33
ubiquitin specific peptidase 33
chr17_-_48474828 7.69 ENST00000576448.1
ENST00000225972.7
LRRC59
leucine rich repeat containing 59
chr1_-_205719295 7.68 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr17_+_60536002 7.67 ENST00000582809.1
TLK2
tousled-like kinase 2
chr3_+_150321068 7.61 ENST00000471696.1
ENST00000477889.1
ENST00000485923.1
SELT
Selenoprotein T
chr1_-_155211017 7.58 ENST00000536770.1
ENST00000368373.3
GBA
glucosidase, beta, acid
chr15_-_59665062 7.51 ENST00000288235.4
MYO1E
myosin IE
chr15_-_73076030 7.48 ENST00000311669.8
ADPGK
ADP-dependent glucokinase
chr3_-_125094093 7.35 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
ZNF148
zinc finger protein 148
chr1_-_211752073 7.33 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr15_+_59279851 7.21 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
RNF111
ring finger protein 111
chrX_+_80457442 6.95 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr7_-_93633684 6.91 ENST00000222547.3
ENST00000425626.1
BET1
Bet1 golgi vesicular membrane trafficking protein
chr12_+_12764773 6.79 ENST00000228865.2
CREBL2
cAMP responsive element binding protein-like 2
chr13_-_107187462 6.70 ENST00000245323.4
EFNB2
ephrin-B2
chr1_+_160175117 6.54 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr11_-_85780086 6.47 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr20_-_62199427 6.41 ENST00000427522.2
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chrX_-_74376108 6.33 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr5_+_34915444 6.15 ENST00000336767.5
BRIX1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chrX_-_41782249 6.14 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr17_+_49230897 6.10 ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
NME1
NME1-NME2
NME2
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 2
chr6_+_43737939 6.04 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr3_-_185655795 6.01 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
TRA2B
transformer 2 beta homolog (Drosophila)
chr3_+_61547585 6.00 ENST00000295874.10
ENST00000474889.1
PTPRG
protein tyrosine phosphatase, receptor type, G
chr3_+_19988566 5.95 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr11_+_69455855 5.82 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr1_-_89458415 5.79 ENST00000321792.5
ENST00000370491.3
RBMXL1
CCBL2
RNA binding motif protein, X-linked-like 1
cysteine conjugate-beta lyase 2
chr2_+_191745560 5.75 ENST00000338435.4
GLS
glutaminase
chr9_+_77703414 5.74 ENST00000346234.6
OSTF1
osteoclast stimulating factor 1
chr4_+_160188889 5.66 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chrX_+_12993202 5.50 ENST00000451311.2
ENST00000380636.1
TMSB4X
thymosin beta 4, X-linked
chr15_+_89631381 5.44 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr12_+_121148228 5.35 ENST00000344651.4
UNC119B
unc-119 homolog B (C. elegans)
chr21_-_34960948 5.27 ENST00000453626.1
ENST00000303113.6
ENST00000432378.1
ENST00000303071.5
DONSON
downstream neighbor of SON
chr17_-_56084578 5.23 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
SRSF1
serine/arginine-rich splicing factor 1
chr10_-_33623564 5.20 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr6_+_71377473 5.13 ENST00000370452.3
ENST00000316999.5
ENST00000370455.3
SMAP1
small ArfGAP 1
chr3_-_11762202 5.00 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
VGLL4
vestigial like 4 (Drosophila)
chr19_+_46010674 4.99 ENST00000245932.6
ENST00000592139.1
ENST00000590603.1
VASP
vasodilator-stimulated phosphoprotein
chr4_-_22517620 4.96 ENST00000502482.1
ENST00000334304.5
GPR125
G protein-coupled receptor 125
chr11_+_35684288 4.83 ENST00000299413.5
TRIM44
tripartite motif containing 44
chr1_+_36348790 4.81 ENST00000373204.4
AGO1
argonaute RISC catalytic component 1
chr2_+_106361333 4.79 ENST00000233154.4
ENST00000451463.2
NCK2
NCK adaptor protein 2
chr6_+_12290586 4.75 ENST00000379375.5
EDN1
endothelin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of GGAAUGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
17.9 53.6 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
15.3 30.5 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
10.9 32.7 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
9.0 27.1 GO:1900369 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
8.8 26.4 GO:0006738 nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
8.6 34.5 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
7.4 14.8 GO:0019322 pentose biosynthetic process(GO:0019322)
6.8 33.9 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
6.0 47.6 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
5.9 41.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
5.3 15.9 GO:1901873 regulation of post-translational protein modification(GO:1901873)
5.3 15.8 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
5.1 15.3 GO:0097327 response to antineoplastic agent(GO:0097327)
4.6 9.3 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
4.4 17.7 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
4.0 12.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016) negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
3.9 11.6 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
3.8 19.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
3.7 18.7 GO:1903976 negative regulation of glial cell migration(GO:1903976)
3.7 18.4 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
3.5 21.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
3.5 10.4 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
3.3 22.9 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
3.2 19.1 GO:0032328 alanine transport(GO:0032328)
3.1 21.7 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
2.9 11.4 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
2.8 14.0 GO:0042256 mature ribosome assembly(GO:0042256)
2.8 14.0 GO:0030047 actin modification(GO:0030047)
2.7 40.9 GO:0090168 Golgi reassembly(GO:0090168)
2.6 7.9 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
2.6 15.4 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
2.5 2.5 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
2.5 17.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
2.4 9.7 GO:0045053 protein retention in Golgi apparatus(GO:0045053) asymmetric Golgi ribbon formation(GO:0090164)
2.3 9.4 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
2.3 2.3 GO:0072197 ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
2.3 9.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
2.2 9.0 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
2.2 13.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.2 15.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
2.1 12.8 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
2.0 28.3 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
2.0 6.0 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
2.0 2.0 GO:0021897 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
1.9 34.9 GO:0032486 Rap protein signal transduction(GO:0032486)
1.9 7.7 GO:0019046 release from viral latency(GO:0019046)
1.9 7.6 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
1.9 18.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.7 17.3 GO:0043622 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660)
1.7 1.7 GO:0003104 positive regulation of glomerular filtration(GO:0003104)
1.7 30.1 GO:0036010 protein localization to endosome(GO:0036010)
1.6 13.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
1.6 17.8 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
1.6 6.5 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
1.6 8.0 GO:0097338 response to clozapine(GO:0097338)
1.6 22.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
1.6 4.7 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
1.6 4.7 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
1.5 10.8 GO:0048194 Golgi vesicle budding(GO:0048194)
1.5 6.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
1.5 14.7 GO:1900125 regulation of hyaluronan biosynthetic process(GO:1900125)
1.4 12.7 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
1.4 8.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
1.3 2.6 GO:1905064 negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
1.3 7.5 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
1.2 7.3 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
1.2 8.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
1.2 13.3 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
1.2 3.6 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
1.2 5.9 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
1.2 10.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
1.2 3.5 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
1.2 10.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.2 13.9 GO:0051451 myoblast migration(GO:0051451)
1.2 6.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
1.1 5.7 GO:0006543 glutamine catabolic process(GO:0006543)
1.1 3.4 GO:0009996 negative regulation of cell fate specification(GO:0009996)
1.1 14.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
1.1 7.8 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
1.1 10.9 GO:0021814 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
1.1 10.8 GO:0045176 apical protein localization(GO:0045176)
1.1 14.9 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
1.0 3.1 GO:0018201 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
1.0 19.6 GO:0051764 actin crosslink formation(GO:0051764)
1.0 10.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
1.0 13.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
1.0 29.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
1.0 15.0 GO:0034063 stress granule assembly(GO:0034063)
1.0 6.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
1.0 2.0 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
1.0 6.0 GO:0051036 regulation of endosome size(GO:0051036)
1.0 22.7 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
1.0 18.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)
1.0 10.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.9 2.8 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.9 4.5 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.9 7.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.9 30.4 GO:0090383 phagosome acidification(GO:0090383)
0.9 17.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.9 30.3 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.8 5.8 GO:0070141 response to UV-A(GO:0070141)
0.8 7.2 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.8 21.3 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.8 8.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.7 5.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.7 5.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.7 3.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.7 16.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.7 3.3 GO:0072719 cellular response to cisplatin(GO:0072719)
0.7 17.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.6 3.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.6 3.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.6 6.3 GO:0015886 heme transport(GO:0015886)
0.6 7.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.6 13.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.6 12.2 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.6 1.7 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.5 10.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.5 18.2 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.5 6.1 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.5 3.5 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.5 4.5 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.5 21.8 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.5 6.5 GO:0046325 negative regulation of glucose import(GO:0046325)
0.5 26.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.5 30.0 GO:0021762 substantia nigra development(GO:0021762)
0.5 2.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.4 1.7 GO:0006408 snRNA export from nucleus(GO:0006408)
0.4 2.9 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.4 0.8 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.4 18.4 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.4 28.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.4 8.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.4 8.6 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498)
0.4 17.1 GO:0043486 histone exchange(GO:0043486)
0.4 1.8 GO:0016240 autophagosome docking(GO:0016240)
0.4 20.2 GO:0007566 embryo implantation(GO:0007566)
0.4 4.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.4 7.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.3 13.9 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.3 15.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.3 13.8 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.3 24.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.3 3.3 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.3 3.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.3 22.6 GO:0032508 DNA duplex unwinding(GO:0032508)
0.3 1.4 GO:0010265 SCF complex assembly(GO:0010265)
0.3 20.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.3 12.2 GO:0006611 protein export from nucleus(GO:0006611)
0.3 3.0 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.3 1.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 15.6 GO:0001895 retina homeostasis(GO:0001895)
0.2 5.4 GO:0048240 sperm capacitation(GO:0048240)
0.2 2.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 0.9 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2 1.5 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 10.9 GO:0019835 cytolysis(GO:0019835)
0.2 7.9 GO:0035329 hippo signaling(GO:0035329)
0.2 5.4 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.2 16.3 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.2 6.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 3.9 GO:0006829 zinc II ion transport(GO:0006829)
0.2 12.6 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.2 7.5 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 6.8 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.1 8.0 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 18.5 GO:0002576 platelet degranulation(GO:0002576)
0.1 0.8 GO:0008105 asymmetric protein localization(GO:0008105)
0.1 4.0 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.1 1.2 GO:0060033 anatomical structure regression(GO:0060033)
0.1 1.0 GO:0070828 heterochromatin organization(GO:0070828)
0.1 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 1.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 5.2 GO:0033260 nuclear DNA replication(GO:0033260)
0.1 17.1 GO:0016579 protein deubiquitination(GO:0016579)
0.1 7.8 GO:0010324 membrane invagination(GO:0010324)
0.1 1.0 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 2.0 GO:0031648 protein destabilization(GO:0031648)
0.1 4.4 GO:0050817 blood coagulation(GO:0007596) coagulation(GO:0050817)
0.1 1.0 GO:0046519 sphingoid metabolic process(GO:0046519)
0.1 10.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 2.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.3 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.1 6.5 GO:0030307 positive regulation of cell growth(GO:0030307)
0.1 3.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 4.1 GO:0051289 protein homotetramerization(GO:0051289)
0.1 0.3 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 6.4 GO:0043279 response to alkaloid(GO:0043279)
0.0 6.5 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 11.8 GO:0006413 translational initiation(GO:0006413)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 5.0 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 3.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 1.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191) vesicle uncoating(GO:0072319)
0.0 1.0 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 1.3 GO:0051028 mRNA transport(GO:0051028)
0.0 1.1 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 2.6 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 7.4 GO:0043687 post-translational protein modification(GO:0043687)
0.0 3.3 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.7 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.5 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.7 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 3.8 GO:0042493 response to drug(GO:0042493)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 30.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
5.4 27.1 GO:0044530 supraspliceosomal complex(GO:0044530)
4.5 31.8 GO:0071203 WASH complex(GO:0071203)
4.1 41.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
3.7 22.2 GO:0030905 retromer, tubulation complex(GO:0030905)
3.6 17.8 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
2.8 16.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
2.7 35.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
2.3 9.3 GO:0005797 Golgi medial cisterna(GO:0005797)
2.3 44.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
2.3 11.4 GO:0042643 actomyosin, actin portion(GO:0042643)
2.2 28.7 GO:0016600 flotillin complex(GO:0016600)
2.2 15.4 GO:0044326 dendritic spine neck(GO:0044326)
2.1 32.9 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
2.0 12.2 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
2.0 7.9 GO:0055087 Ski complex(GO:0055087)
1.9 20.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.9 13.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
1.8 14.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
1.8 14.6 GO:0042382 paraspeckles(GO:0042382)
1.6 19.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.5 7.7 GO:0030891 VCB complex(GO:0030891)
1.3 12.7 GO:0001739 sex chromatin(GO:0001739)
1.2 19.6 GO:0043073 germ cell nucleus(GO:0043073)
1.2 21.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
1.2 4.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.1 10.9 GO:0044327 dendritic spine head(GO:0044327)
1.1 8.7 GO:0035976 AP1 complex(GO:0035976)
1.1 6.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
1.0 8.0 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
1.0 12.7 GO:0097227 sperm annulus(GO:0097227)
0.9 9.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.9 1.8 GO:1903349 omegasome membrane(GO:1903349)
0.9 9.0 GO:0097433 dense body(GO:0097433)
0.9 49.2 GO:0031941 filamentous actin(GO:0031941)
0.8 10.1 GO:0043219 lateral loop(GO:0043219)
0.8 51.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.8 17.1 GO:0000812 Swr1 complex(GO:0000812)
0.8 10.6 GO:0097470 ribbon synapse(GO:0097470)
0.8 14.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.8 10.8 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.8 7.6 GO:0097443 sorting endosome(GO:0097443)
0.7 6.0 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.7 16.5 GO:0071141 SMAD protein complex(GO:0071141)
0.7 4.2 GO:0070545 PeBoW complex(GO:0070545)
0.7 15.8 GO:0000242 pericentriolar material(GO:0000242)
0.7 19.5 GO:0035861 site of double-strand break(GO:0035861)
0.6 10.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.6 3.6 GO:0000322 storage vacuole(GO:0000322)
0.6 20.2 GO:0000421 autophagosome membrane(GO:0000421)
0.6 8.3 GO:0033643 host cell part(GO:0033643)
0.5 36.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.5 28.3 GO:0031519 PcG protein complex(GO:0031519)
0.5 38.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.5 13.5 GO:0097228 sperm principal piece(GO:0097228)
0.5 5.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.5 37.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.4 8.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 6.1 GO:0005652 nuclear lamina(GO:0005652)
0.4 2.0 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.4 11.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.4 8.6 GO:0071564 npBAF complex(GO:0071564)
0.4 2.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.3 16.0 GO:0043198 dendritic shaft(GO:0043198)
0.3 2.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.3 9.1 GO:0002102 podosome(GO:0002102)
0.3 1.7 GO:0005916 fascia adherens(GO:0005916)
0.3 20.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 3.5 GO:0005577 fibrinogen complex(GO:0005577)
0.3 29.3 GO:0031985 Golgi cisterna(GO:0031985)
0.3 78.6 GO:0031965 nuclear membrane(GO:0031965)
0.2 5.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 33.0 GO:0032587 ruffle membrane(GO:0032587)
0.2 19.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 40.1 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.2 10.6 GO:0036126 sperm flagellum(GO:0036126)
0.2 5.4 GO:0035869 ciliary transition zone(GO:0035869)
0.2 26.6 GO:0005903 brush border(GO:0005903)
0.2 5.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 3.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 15.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 18.8 GO:0070469 respiratory chain(GO:0070469)
0.2 6.5 GO:0005801 cis-Golgi network(GO:0005801)
0.2 7.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 3.2 GO:0009925 basal plasma membrane(GO:0009925)
0.2 8.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 17.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 13.9 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 22.2 GO:0005741 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.1 21.5 GO:0030027 lamellipodium(GO:0030027)
0.1 5.8 GO:1990904 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.1 24.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 34.7 GO:0016324 apical plasma membrane(GO:0016324)
0.1 10.9 GO:0031902 late endosome membrane(GO:0031902)
0.1 3.5 GO:0005771 multivesicular body(GO:0005771)
0.1 3.1 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.1 2.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 11.0 GO:0043197 dendritic spine(GO:0043197)
0.1 13.4 GO:0000922 spindle pole(GO:0000922)
0.1 7.7 GO:0005882 intermediate filament(GO:0005882)
0.1 3.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 7.6 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.3 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 4.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 4.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 12.8 GO:0005925 focal adhesion(GO:0005925)
0.0 10.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 74.0 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 2.5 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.9 GO:0010008 endosome membrane(GO:0010008)
0.0 0.3 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.8 26.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
7.9 23.6 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
7.2 21.7 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
6.8 27.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
6.4 19.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
5.1 30.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
4.9 14.8 GO:0004802 transketolase activity(GO:0004802)
4.9 34.5 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
4.4 22.2 GO:1990460 leptin receptor binding(GO:1990460)
4.4 17.7 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
4.2 12.7 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
4.1 12.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
4.0 11.9 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
3.3 13.3 GO:0005046 KDEL sequence binding(GO:0005046)
3.1 18.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
3.1 9.3 GO:0033149 FFAT motif binding(GO:0033149)
2.8 38.8 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
2.6 28.3 GO:0046790 virion binding(GO:0046790)
2.5 14.9 GO:0035500 MH2 domain binding(GO:0035500)
2.4 7.2 GO:0032184 SUMO polymer binding(GO:0032184)
2.3 18.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
2.2 13.3 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.2 30.3 GO:0030215 semaphorin receptor binding(GO:0030215)
1.9 7.6 GO:0004348 glucosylceramidase activity(GO:0004348)
1.7 23.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
1.6 24.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
1.6 14.7 GO:0032051 clathrin light chain binding(GO:0032051)
1.6 9.7 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.6 21.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
1.6 4.7 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
1.5 10.6 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.5 17.8 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
1.4 20.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.4 8.3 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.3 4.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
1.3 24.0 GO:0004859 phospholipase inhibitor activity(GO:0004859)
1.2 24.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
1.2 3.6 GO:0032427 GBD domain binding(GO:0032427)
1.1 5.7 GO:0004359 glutaminase activity(GO:0004359)
1.1 9.1 GO:0016778 diphosphotransferase activity(GO:0016778)
1.1 30.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
1.1 15.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
1.1 8.6 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
1.0 3.1 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
1.0 25.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
1.0 10.5 GO:0097016 L27 domain binding(GO:0097016)
0.9 4.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.9 10.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.9 8.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.9 40.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.9 3.5 GO:0070051 fibrinogen binding(GO:0070051)
0.9 34.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.8 13.8 GO:0043022 ribosome binding(GO:0043022)
0.8 18.6 GO:0070402 NADPH binding(GO:0070402)
0.8 10.4 GO:0016595 glutamate binding(GO:0016595)
0.8 11.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.8 25.6 GO:0003785 actin monomer binding(GO:0003785)
0.8 21.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.8 10.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.7 17.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.7 7.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.7 24.4 GO:0070717 poly-purine tract binding(GO:0070717)
0.7 19.6 GO:0070410 co-SMAD binding(GO:0070410)
0.7 8.0 GO:0034452 dynactin binding(GO:0034452)
0.6 49.4 GO:0019003 GDP binding(GO:0019003)
0.6 10.8 GO:0004697 protein kinase C activity(GO:0004697)
0.6 6.3 GO:0015232 heme transporter activity(GO:0015232)
0.6 7.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.6 21.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.6 15.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.6 37.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.6 22.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.6 5.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.6 15.1 GO:0070034 telomerase RNA binding(GO:0070034)
0.6 8.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.5 131.2 GO:0051015 actin filament binding(GO:0051015)
0.5 6.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.5 3.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.5 21.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.5 8.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 15.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.5 18.0 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.5 1.0 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.5 6.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.5 2.4 GO:0050693 LBD domain binding(GO:0050693)
0.5 5.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.5 1.8 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.4 6.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 10.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4 1.7 GO:0071253 connexin binding(GO:0071253)
0.4 63.1 GO:0044325 ion channel binding(GO:0044325)
0.4 16.9 GO:0019894 kinesin binding(GO:0019894)
0.4 5.0 GO:0005522 profilin binding(GO:0005522)
0.4 2.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 17.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.3 3.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.3 3.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.3 25.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.3 5.1 GO:0030276 clathrin binding(GO:0030276)
0.3 17.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 4.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.3 0.8 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 32.9 GO:0008565 protein transporter activity(GO:0008565)
0.3 2.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.2 7.9 GO:0032452 histone demethylase activity(GO:0032452)
0.2 19.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 6.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 1.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 0.7 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 13.5 GO:0003777 microtubule motor activity(GO:0003777)
0.2 2.9 GO:0051400 BH domain binding(GO:0051400)
0.2 18.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.2 13.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 0.8 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 10.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 49.8 GO:0045296 cadherin binding(GO:0045296)
0.1 10.9 GO:0060089 receptor activity(GO:0004872) molecular transducer activity(GO:0060089)
0.1 19.3 GO:0020037 heme binding(GO:0020037)
0.1 2.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 10.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.7 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.0 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 4.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 12.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 9.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.1 GO:0008252 nucleotidase activity(GO:0008252)
0.1 5.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 1.0 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.8 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1 12.8 GO:0003823 antigen binding(GO:0003823)
0.1 1.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 4.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 2.5 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 4.0 GO:0004386 helicase activity(GO:0004386)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0032027 C-X-C chemokine receptor activity(GO:0016494) myosin light chain binding(GO:0032027)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 39.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.0 19.1 PID IL5 PATHWAY IL5-mediated signaling events
1.0 48.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.9 39.0 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.9 30.3 PID IL3 PATHWAY IL3-mediated signaling events
0.5 14.4 PID INSULIN PATHWAY Insulin Pathway
0.5 26.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.5 32.7 PID PLK1 PATHWAY PLK1 signaling events
0.5 37.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.5 22.0 PID ARF6 PATHWAY Arf6 signaling events
0.5 20.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.4 28.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.4 15.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 26.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 18.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.3 8.6 PID CDC42 PATHWAY CDC42 signaling events
0.3 11.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3 6.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.3 8.0 PID REELIN PATHWAY Reelin signaling pathway
0.3 51.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 9.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.3 7.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 30.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 4.7 PID ENDOTHELIN PATHWAY Endothelins
0.2 18.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 5.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 13.8 PID E2F PATHWAY E2F transcription factor network
0.2 1.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 8.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 3.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 6.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 8.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 2.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 7.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 17.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 1.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 6.7 PID P73PATHWAY p73 transcription factor network
0.0 2.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 26.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
2.1 22.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
2.0 28.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.8 44.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
1.2 19.8 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
1.2 35.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
1.2 29.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.1 29.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.9 9.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.9 16.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.9 27.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.9 18.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.9 29.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.8 25.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.8 15.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.7 30.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.6 13.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.6 8.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.6 18.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.6 13.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.6 20.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.5 3.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.5 13.5 REACTOME KINESINS Genes involved in Kinesins
0.5 22.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.5 13.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.5 7.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.5 15.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.4 34.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.4 8.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 3.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.4 16.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.4 5.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.4 25.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.4 42.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.4 29.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 34.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.3 20.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.3 30.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 11.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.3 10.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 7.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 17.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 2.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 9.0 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2 17.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 5.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 12.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 2.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 10.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 7.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 14.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.2 34.2 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.2 15.1 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 23.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 5.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 12.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 24.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 7.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 3.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 2.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 3.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors