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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GLI3

Z-value: 1.03

Motif logo

Transcription factors associated with GLI3

Gene Symbol Gene ID Gene Info
ENSG00000106571.8 GLI family zinc finger 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLI3hg19_v2_chr7_-_42276612_422767820.341.8e-07Click!

Activity profile of GLI3 motif

Sorted Z-values of GLI3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_153839149 24.09 ENST00000465093.1
ENST00000465817.1
Rho guanine nucleotide exchange factor (GEF) 26
chr8_-_27462822 15.32 ENST00000522098.1
clusterin
chr22_+_23247030 13.72 ENST00000390324.2
immunoglobulin lambda joining 3
chr19_+_35521616 13.29 ENST00000595652.1
sodium channel, voltage-gated, type I, beta subunit
chr8_-_27468842 13.08 ENST00000523500.1
clusterin
chr19_+_45417921 12.88 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
apolipoprotein C-I
chr11_-_111783919 12.13 ENST00000531198.1
ENST00000533879.1
crystallin, alpha B
chr19_+_45417812 12.07 ENST00000592535.1
apolipoprotein C-I
chr5_-_42825983 11.40 ENST00000506577.1
selenoprotein P, plasma, 1
chr11_-_111784005 11.39 ENST00000527899.1
crystallin, alpha B
chr3_+_45067659 11.31 ENST00000296130.4
C-type lectin domain family 3, member B
chr1_+_6845384 11.10 ENST00000303635.7
calmodulin binding transcription activator 1
chr19_+_45417504 10.97 ENST00000588750.1
ENST00000588802.1
apolipoprotein C-I
chr19_+_45418067 10.56 ENST00000589078.1
ENST00000586638.1
apolipoprotein C-I
chr4_-_57524061 10.38 ENST00000508121.1
HOP homeobox
chr6_-_159420780 10.10 ENST00000449822.1
radial spoke 3 homolog (Chlamydomonas)
chr9_-_98079965 9.83 ENST00000289081.3
Fanconi anemia, complementation group C
chr1_-_204380919 9.55 ENST00000367188.4
protein phosphatase 1, regulatory subunit 15B
chr5_-_149792295 9.38 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74 molecule, major histocompatibility complex, class II invariant chain
chr9_+_139871948 9.38 ENST00000224167.2
ENST00000457950.1
ENST00000371625.3
ENST00000371623.3
prostaglandin D2 synthase 21kDa (brain)
chr10_-_90712520 9.05 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr3_-_15469006 8.93 ENST00000443029.1
ENST00000383790.3
ENST00000383789.5
methyltransferase like 6
chr17_+_4710391 8.65 ENST00000263088.6
ENST00000572940.1
phospholipase D2
chr19_-_17185848 8.55 ENST00000593360.1
HAUS augmin-like complex, subunit 8
chr2_-_201936302 8.30 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
family with sequence similarity 126, member B
chr19_-_16653226 8.07 ENST00000198939.6
calcium homeostasis endoplasmic reticulum protein
chr8_-_27468945 7.98 ENST00000405140.3
clusterin
chr14_+_29236269 7.97 ENST00000313071.4
forkhead box G1
chr16_+_85061367 7.95 ENST00000538274.1
ENST00000258180.3
KIAA0513
chr2_+_17935383 7.88 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chr20_+_62185491 7.78 ENST00000370097.1
chromosome 20 open reading frame 195
chr12_-_6798616 7.45 ENST00000355772.4
ENST00000417772.3
ENST00000396801.3
ENST00000396799.2
zinc finger protein 384
chr19_+_2096868 7.40 ENST00000395296.1
ENST00000395301.3
IZUMO family member 4
chr14_+_94577074 7.39 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr4_+_166300084 7.27 ENST00000402744.4
carboxypeptidase E
chr2_+_17935119 7.22 ENST00000317402.7
GEN1 Holliday junction 5' flap endonuclease
chr1_+_156123359 7.19 ENST00000368284.1
ENST00000368286.2
ENST00000438830.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr22_+_23241661 7.17 ENST00000390322.2
immunoglobulin lambda joining 2
chr8_+_21916710 7.15 ENST00000523266.1
ENST00000519907.1
dematin actin binding protein
chr19_-_16653325 7.05 ENST00000546361.2
calcium homeostasis endoplasmic reticulum protein
chr3_+_10068095 7.00 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
Fanconi anemia, complementation group D2
chr11_-_111783595 6.98 ENST00000528628.1
crystallin, alpha B
chr19_+_35521572 6.83 ENST00000262631.5
sodium channel, voltage-gated, type I, beta subunit
chr2_-_136875712 6.81 ENST00000241393.3
chemokine (C-X-C motif) receptor 4
chr14_+_102027688 6.77 ENST00000510508.4
ENST00000359323.3
deiodinase, iodothyronine, type III
chr11_-_12030629 6.70 ENST00000396505.2
dickkopf WNT signaling pathway inhibitor 3
chr8_+_21916680 6.68 ENST00000358242.3
ENST00000415253.1
dematin actin binding protein
chr1_-_20834586 6.67 ENST00000264198.3
mitochondrial E3 ubiquitin protein ligase 1
chr15_+_81591757 6.56 ENST00000558332.1
interleukin 16
chr7_+_150498783 6.53 ENST00000475536.1
ENST00000468689.1
transmembrane protein 176A
chr12_-_6798523 6.48 ENST00000319770.3
zinc finger protein 384
chr3_-_46506358 6.46 ENST00000417439.1
ENST00000431944.1
lactotransferrin
chr20_-_50808236 6.44 ENST00000361387.2
ZFP64 zinc finger protein
chr1_+_156123318 6.42 ENST00000368285.3
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr19_+_39897453 6.33 ENST00000597629.1
ENST00000248673.3
ENST00000594045.1
ENST00000594442.1
ZFP36 ring finger protein
chr3_+_15468862 6.28 ENST00000396842.2
ELL associated factor 1
chr1_+_36396313 6.21 ENST00000324350.5
argonaute RISC catalytic component 3
chr16_+_84209539 6.16 ENST00000569735.1
dynein, axonemal, assembly factor 1
chr12_-_6798410 6.16 ENST00000361959.3
ENST00000436774.2
ENST00000544482.1
zinc finger protein 384
chr7_+_150498610 6.15 ENST00000461345.1
transmembrane protein 176A
chr15_+_84116106 6.08 ENST00000535412.1
ENST00000324537.5
SH3-domain GRB2-like 3
chr19_+_48281842 6.05 ENST00000509570.2
selenoprotein W, 1
chr12_-_45270151 6.02 ENST00000429094.2
NEL-like 2 (chicken)
chr20_+_36149602 5.99 ENST00000062104.2
ENST00000346199.2
neuronatin
chr12_-_13248705 5.92 ENST00000396310.2
germ cell associated 1
chr17_+_17942684 5.91 ENST00000376345.3
GID complex subunit 4
chr12_-_45270077 5.88 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chr17_+_17942594 5.87 ENST00000268719.4
GID complex subunit 4
chr12_-_122751002 5.85 ENST00000267199.4
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr21_-_45079341 5.84 ENST00000443485.1
ENST00000291560.2
heat shock transcription factor 2 binding protein
chr19_-_46318561 5.69 ENST00000221538.3
radial spoke head 6 homolog A (Chlamydomonas)
chr11_-_65640325 5.62 ENST00000307998.6
EGF containing fibulin-like extracellular matrix protein 2
chr19_-_46318486 5.57 ENST00000597055.1
radial spoke head 6 homolog A (Chlamydomonas)
chr6_-_46703069 5.47 ENST00000538237.1
ENST00000274793.7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr6_-_167040731 5.41 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr19_+_35629702 5.39 ENST00000351325.4
FXYD domain containing ion transport regulator 1
chr1_-_21978312 5.38 ENST00000359708.4
ENST00000290101.4
RAP1 GTPase activating protein
chr1_+_11866270 5.38 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
chloride channel, voltage-sensitive 6
chr21_-_46330545 5.35 ENST00000320216.6
ENST00000397852.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_-_11866034 5.23 ENST00000376590.3
methylenetetrahydrofolate reductase (NAD(P)H)
chr3_-_127542051 5.22 ENST00000398104.1
monoglyceride lipase
chr3_-_15140629 5.17 ENST00000507357.1
ENST00000449050.1
ENST00000253699.3
ENST00000435849.3
ENST00000476527.2
zinc finger, FYVE domain containing 20
chr6_-_28367510 5.11 ENST00000361028.1
zinc finger and SCAN domain containing 12
chr11_-_65640198 5.10 ENST00000528176.1
EGF containing fibulin-like extracellular matrix protein 2
chr19_+_44084696 5.09 ENST00000562255.1
ENST00000569031.2
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr15_+_59499031 5.03 ENST00000307144.4
lactate dehydrogenase A-like 6B
chr3_+_49591881 5.01 ENST00000296452.4
bassoon presynaptic cytomatrix protein
chr19_+_58790314 5.01 ENST00000196548.5
ENST00000608843.1
Zinc finger protein 8
zinc finger protein 8
chr12_+_50355647 5.01 ENST00000293599.6
aquaporin 5
chr4_-_17812309 4.97 ENST00000382247.1
ENST00000536863.1
DDB1 and CUL4 associated factor 16
chr1_-_11865982 4.96 ENST00000418034.1
methylenetetrahydrofolate reductase (NAD(P)H)
chr19_+_1103936 4.95 ENST00000354171.8
ENST00000589115.1
glutathione peroxidase 4
chr9_-_123476612 4.92 ENST00000426959.1
multiple EGF-like-domains 9
chr16_+_28834303 4.88 ENST00000340394.8
ENST00000325215.6
ENST00000395547.2
ENST00000336783.4
ENST00000382686.4
ENST00000564304.1
ataxin 2-like
chrX_-_40506766 4.87 ENST00000378421.1
ENST00000440784.2
ENST00000327877.5
ENST00000378426.1
ENST00000378418.2
chromosome X open reading frame 38
chr19_-_3869012 4.86 ENST00000592398.1
ENST00000262961.4
ENST00000439086.2
zinc finger RNA binding protein 2
chr10_-_27444143 4.86 ENST00000477432.1
YME1-like 1 ATPase
chr9_-_131872928 4.86 ENST00000455830.2
ENST00000393384.3
ENST00000318080.2
carnitine O-acetyltransferase
chr11_-_2160180 4.85 ENST00000381406.4
insulin-like growth factor 2 (somatomedin A)
chr4_-_74847800 4.82 ENST00000296029.3
platelet factor 4
chr4_+_72052964 4.74 ENST00000264485.5
ENST00000425175.1
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr12_+_10365404 4.74 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr14_-_107114267 4.68 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr19_-_33793430 4.64 ENST00000498907.2
CCAAT/enhancer binding protein (C/EBP), alpha
chr9_+_134000948 4.61 ENST00000359428.5
ENST00000411637.2
ENST00000451030.1
nucleoporin 214kDa
chr9_+_34458771 4.51 ENST00000437363.1
ENST00000242317.4
dynein, axonemal, intermediate chain 1
chr1_+_9005917 4.49 ENST00000549778.1
ENST00000480186.3
ENST00000377443.2
ENST00000377436.3
ENST00000377442.2
carbonic anhydrase VI
chr19_-_4454081 4.48 ENST00000591919.1
UBX domain protein 6
chr16_+_67381289 4.45 ENST00000435835.3
leucine rich repeat containing 36
chr7_-_994302 4.45 ENST00000265846.5
ArfGAP with dual PH domains 1
chr17_+_42219267 4.43 ENST00000319977.4
ENST00000585683.1
chromosome 17 open reading frame 53
chr19_+_782755 4.41 ENST00000606242.1
ENST00000586061.1
AC006273.5
chr4_-_5894777 4.41 ENST00000324989.7
collapsin response mediator protein 1
chr7_-_105029812 4.41 ENST00000482897.1
SRSF protein kinase 2
chr19_+_48281803 4.40 ENST00000601048.1
selenoprotein W, 1
chr5_-_180237445 4.39 ENST00000393340.3
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr16_+_20817761 4.37 ENST00000568046.1
ENST00000261377.6
Putative RNA exonuclease NEF-sp
chr16_+_67381263 4.34 ENST00000541146.1
ENST00000563189.1
ENST00000290940.7
leucine rich repeat containing 36
chr19_+_49999631 4.32 ENST00000270625.2
ENST00000596873.1
ENST00000594493.1
ENST00000599561.1
ribosomal protein S11
chr8_+_133931648 4.28 ENST00000519178.1
ENST00000542445.1
thyroglobulin
chr19_+_4969116 4.27 ENST00000588337.1
ENST00000159111.4
ENST00000381759.4
lysine (K)-specific demethylase 4B
chr6_+_163148973 4.27 ENST00000366888.2
PARK2 co-regulated
chr1_+_19923454 4.25 ENST00000602662.1
ENST00000602293.1
ENST00000322753.6
MINOS1-NBL1 readthrough
mitochondrial inner membrane organizing system 1
chr12_-_13248562 4.17 ENST00000457134.2
ENST00000537302.1
germ cell associated 1
chr17_+_7531281 4.16 ENST00000575729.1
ENST00000340624.5
sex hormone-binding globulin
chr12_-_10542617 4.15 ENST00000240618.6
killer cell lectin-like receptor subfamily K, member 1
chr1_+_11866207 4.13 ENST00000312413.6
ENST00000346436.6
chloride channel, voltage-sensitive 6
chr19_+_5455421 4.12 ENST00000222033.4
zinc and ring finger 4
chr2_+_220379052 4.12 ENST00000347842.3
ENST00000358078.4
acid-sensing (proton-gated) ion channel family member 4
chr17_+_42219383 4.11 ENST00000245382.6
chromosome 17 open reading frame 53
chr16_+_57702099 4.10 ENST00000333493.4
ENST00000327655.6
G protein-coupled receptor 97
chr11_-_116708302 4.10 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
apolipoprotein A-I
chr10_+_134145614 4.10 ENST00000368615.3
ENST00000392638.2
ENST00000344079.5
ENST00000356571.4
ENST00000368614.3
leucine rich repeat containing 27
chrX_-_48056199 4.09 ENST00000311798.1
ENST00000347757.1
synovial sarcoma, X breakpoint 5
chr17_-_73851285 4.08 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WW domain binding protein 2
chr4_+_76932326 4.06 ENST00000513353.1
ENST00000341029.5
ADP-ribosyltransferase 3
chr12_-_52887034 4.05 ENST00000330722.6
keratin 6A
chr19_+_36208877 4.02 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
Histone-lysine N-methyltransferase 2B
chr14_-_60097524 3.98 ENST00000342503.4
reticulon 1
chr17_-_1420182 3.98 ENST00000421807.2
inositol polyphosphate-5-phosphatase K
chr1_-_31845914 3.98 ENST00000373713.2
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr12_-_13248732 3.96 ENST00000396302.3
germ cell associated 1
chr5_+_80597419 3.96 ENST00000254037.2
ENST00000407610.3
ENST00000380199.5
zinc finger, CCHC domain containing 9
chr20_+_44098346 3.95 ENST00000372676.3
WAP four-disulfide core domain 2
chr14_-_94856987 3.95 ENST00000449399.3
ENST00000404814.4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr9_+_90112590 3.92 ENST00000472284.1
death-associated protein kinase 1
chr6_-_46703430 3.91 ENST00000537365.1
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr19_-_19754354 3.90 ENST00000587238.1
GEM interacting protein
chr11_+_111783450 3.88 ENST00000537382.1
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr21_-_46340884 3.88 ENST00000302347.5
ENST00000517819.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr14_-_94857004 3.87 ENST00000557492.1
ENST00000448921.1
ENST00000437397.1
ENST00000355814.4
ENST00000393088.4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr19_-_12886327 3.87 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
hook microtubule-tethering protein 2
chr14_-_106330072 3.87 ENST00000488476.1
immunoglobulin heavy joining 5
chr14_-_94856951 3.86 ENST00000553327.1
ENST00000556955.1
ENST00000557118.1
ENST00000440909.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr17_+_8339189 3.85 ENST00000585098.1
ENST00000380025.4
ENST00000402554.3
ENST00000584866.1
ENST00000582490.1
nudE neurodevelopment protein 1-like 1
chr7_-_150974494 3.84 ENST00000392811.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr20_+_42143136 3.83 ENST00000373134.1
l(3)mbt-like 1 (Drosophila)
chr1_-_229569834 3.80 ENST00000366684.3
ENST00000366683.2
actin, alpha 1, skeletal muscle
chr3_-_169899504 3.77 ENST00000474275.1
ENST00000484931.1
ENST00000494943.1
ENST00000497658.1
ENST00000465896.1
ENST00000475729.1
ENST00000495893.2
ENST00000481639.1
ENST00000467570.1
ENST00000466189.1
polyhomeotic homolog 3 (Drosophila)
chr3_-_53080047 3.77 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
Scm-like with four mbt domains 1
chr16_-_55867146 3.77 ENST00000422046.2
carboxylesterase 1
chr14_-_21492113 3.75 ENST00000554094.1
NDRG family member 2
chr3_+_187871060 3.74 ENST00000448637.1
LIM domain containing preferred translocation partner in lipoma
chr6_-_52859968 3.74 ENST00000370959.1
glutathione S-transferase alpha 4
chr11_+_1889880 3.73 ENST00000405957.2
lymphocyte-specific protein 1
chr11_-_2170786 3.72 ENST00000300632.5
insulin-like growth factor 2 (somatomedin A)
chr20_+_44098385 3.72 ENST00000217425.5
ENST00000339946.3
WAP four-disulfide core domain 2
chr3_-_127542021 3.72 ENST00000434178.2
monoglyceride lipase
chr5_-_95297534 3.72 ENST00000513343.1
ENST00000431061.2
elongation factor, RNA polymerase II, 2
chr15_+_63569731 3.71 ENST00000261879.5
APH1B gamma secretase subunit
chr9_+_131218336 3.68 ENST00000372814.3
outer dense fiber of sperm tails 2
chr1_+_27114589 3.67 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
phosphatidylinositol glycan anchor biosynthesis, class V
chr19_+_35630022 3.67 ENST00000589209.1
FXYD domain containing ion transport regulator 1
chr5_-_79551838 3.65 ENST00000509193.1
ENST00000512972.2
serine incorporator 5
chr1_-_157108266 3.64 ENST00000326786.4
ets variant 3
chr16_-_89556942 3.63 ENST00000301030.4
ankyrin repeat domain 11
chr20_+_49348081 3.62 ENST00000371610.2
par-6 family cell polarity regulator beta
chr19_+_18208603 3.61 ENST00000262811.6
microtubule associated serine/threonine kinase 3
chr6_+_89790459 3.61 ENST00000369472.1
proline-rich nuclear receptor coactivator 1
chr6_-_41747595 3.61 ENST00000373018.3
fibroblast growth factor receptor substrate 3
chr16_-_850723 3.56 ENST00000248150.4
guanine nucleotide binding protein (G protein), gamma 13
chr2_+_25015968 3.55 ENST00000380834.2
ENST00000473706.1
centromere protein O
chr20_-_62258394 3.53 ENST00000370077.1
glucocorticoid modulatory element binding protein 2
chr14_+_105155925 3.52 ENST00000330634.7
ENST00000398337.4
ENST00000392634.4
inverted formin, FH2 and WH2 domain containing
chr20_+_44637526 3.51 ENST00000372330.3
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chrX_-_7895755 3.46 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
patatin-like phospholipase domain containing 4
chr12_-_54978086 3.46 ENST00000553113.1
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr7_-_108166505 3.45 ENST00000426128.2
ENST00000427008.1
ENST00000388728.5
ENST00000257694.8
ENST00000422087.1
ENST00000453144.1
ENST00000436062.1
patatin-like phospholipase domain containing 8
chr9_+_87285539 3.45 ENST00000359847.3
neurotrophic tyrosine kinase, receptor, type 2
chr12_-_54582655 3.44 ENST00000504338.1
ENST00000514685.1
ENST00000504797.1
ENST00000513838.1
ENST00000505128.1
ENST00000337581.3
ENST00000503306.1
ENST00000243112.5
ENST00000514196.1
ENST00000506169.1
ENST00000507904.1
ENST00000508394.2
single-strand-selective monofunctional uracil-DNA glycosylase 1
chr19_+_708910 3.44 ENST00000264560.7
paralemmin
chr14_-_106322288 3.43 ENST00000390559.2
immunoglobulin heavy constant mu
chr9_+_90112767 3.42 ENST00000408954.3
death-associated protein kinase 1
chr21_-_46348694 3.41 ENST00000355153.4
ENST00000397850.2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr9_-_113800317 3.41 ENST00000374431.3
lysophosphatidic acid receptor 1
chr8_-_98290087 3.40 ENST00000322128.3
TSPY-like 5
chr11_-_115630900 3.40 ENST00000537070.1
ENST00000499809.1
ENST00000514294.2
ENST00000535683.1
long intergenic non-protein coding RNA 900
chr1_+_92414928 3.40 ENST00000362005.3
ENST00000370389.2
ENST00000399546.2
ENST00000423434.1
ENST00000394530.3
ENST00000440509.1
bromodomain, testis-specific
chrX_+_52780318 3.39 ENST00000375515.3
ENST00000276049.6
synovial sarcoma, X breakpoint 2B
chr11_-_117103208 3.37 ENST00000320934.3
ENST00000530269.1
proprotein convertase subtilisin/kexin type 7

Network of associatons between targets according to the STRING database.

First level regulatory network of GLI3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
11.6 46.5 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
6.7 20.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
6.1 36.4 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
5.0 15.1 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
2.6 10.5 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
2.4 7.1 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
2.3 9.3 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
2.3 13.8 GO:0070560 protein secretion by platelet(GO:0070560)
2.2 6.5 GO:1900159 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
2.1 12.8 GO:0090131 mesenchyme migration(GO:0090131)
2.1 2.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
2.1 2.1 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
2.0 10.2 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
2.0 23.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
1.9 9.4 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
1.8 5.4 GO:0071810 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
1.8 5.4 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
1.8 8.9 GO:0045918 negative regulation of cytolysis(GO:0045918)
1.7 13.9 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
1.7 6.9 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
1.7 30.5 GO:0007021 tubulin complex assembly(GO:0007021)
1.7 6.7 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
1.7 13.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
1.7 6.6 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.7 5.0 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
1.6 1.6 GO:0050684 regulation of mRNA processing(GO:0050684)
1.6 4.9 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
1.6 4.8 GO:0051037 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
1.6 9.6 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
1.6 10.9 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
1.5 4.4 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
1.5 7.3 GO:0030070 insulin processing(GO:0030070)
1.3 6.7 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
1.3 4.0 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.3 8.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.2 6.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
1.2 7.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.1 3.3 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
1.1 13.1 GO:0036158 outer dynein arm assembly(GO:0036158)
1.1 9.6 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
1.0 6.2 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
1.0 3.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
1.0 3.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
1.0 14.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
1.0 4.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
1.0 14.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.0 5.0 GO:0015670 carbon dioxide transport(GO:0015670)
1.0 4.0 GO:0042335 cuticle development(GO:0042335)
1.0 3.0 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
1.0 6.8 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
1.0 4.9 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.0 8.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.9 6.5 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.9 3.7 GO:0003095 pressure natriuresis(GO:0003095)
0.9 4.4 GO:0035063 nuclear speck organization(GO:0035063)
0.8 4.2 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.8 2.5 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.8 3.2 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.8 2.4 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.8 2.4 GO:0009447 putrescine catabolic process(GO:0009447)
0.8 2.4 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.8 0.8 GO:0046164 alcohol catabolic process(GO:0046164)
0.8 3.9 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.8 3.8 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.8 3.0 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.7 2.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046) establishment of meiotic spindle localization(GO:0051295)
0.7 3.6 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.7 12.8 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.7 2.0 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.7 4.0 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.7 3.3 GO:0002159 desmosome assembly(GO:0002159)
0.6 3.2 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.6 4.5 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.6 7.0 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.6 2.5 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.6 12.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.6 6.0 GO:0009249 protein lipoylation(GO:0009249)
0.6 2.4 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.6 4.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.6 2.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.6 9.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.5 2.2 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.5 3.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.5 1.6 GO:1902996 regulation of neurofibrillary tangle assembly(GO:1902996)
0.5 2.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.5 4.3 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.5 2.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.5 2.7 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626) response to odorant(GO:1990834)
0.5 4.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.5 2.1 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.5 1.6 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.5 3.6 GO:0009597 detection of virus(GO:0009597)
0.5 10.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.5 2.6 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.5 2.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.5 1.5 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.5 3.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.5 10.5 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.5 2.0 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.5 1.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.5 2.0 GO:0071373 cellular response to luteinizing hormone stimulus(GO:0071373)
0.5 3.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.5 2.0 GO:0019086 late viral transcription(GO:0019086)
0.5 8.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.5 4.3 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.5 1.9 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.5 1.4 GO:1900082 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.5 0.5 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.5 0.9 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.5 1.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.5 6.5 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.5 1.8 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.5 3.6 GO:0015705 iodide transport(GO:0015705)
0.5 3.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.4 1.8 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.4 1.3 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.4 3.6 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.4 4.9 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.4 1.3 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.4 1.8 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.4 1.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.4 3.4 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.4 3.9 GO:0008090 retrograde axonal transport(GO:0008090)
0.4 12.7 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.4 6.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.4 2.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 3.8 GO:1904424 regulation of GTP binding(GO:1904424)
0.4 4.6 GO:0045945 urea cycle(GO:0000050) positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.4 2.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.4 3.8 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.4 1.7 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.4 1.2 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.4 6.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.4 1.2 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.4 0.8 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.4 1.9 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.4 1.9 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.4 3.8 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.4 1.1 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.4 2.2 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.4 2.5 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.4 1.4 GO:0015808 L-alanine transport(GO:0015808)
0.4 1.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.4 7.8 GO:0097502 mannosylation(GO:0097502)
0.4 1.4 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.3 1.0 GO:0044705 mating behavior(GO:0007617) reproductive behavior(GO:0019098) multi-organism reproductive behavior(GO:0044705)
0.3 1.0 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.3 1.0 GO:0070086 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.3 1.0 GO:0090155 glucosylceramide biosynthetic process(GO:0006679) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.3 2.9 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.3 4.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.3 2.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.3 0.3 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.3 2.6 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.3 0.6 GO:0060992 response to fungicide(GO:0060992)
0.3 4.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.3 5.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.3 5.7 GO:0090494 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.3 1.0 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.3 0.9 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) mesoderm migration involved in gastrulation(GO:0007509) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.3 0.9 GO:1903960 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960)
0.3 0.9 GO:0001554 luteolysis(GO:0001554)
0.3 4.0 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.3 6.0 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.3 1.5 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.3 0.9 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.3 1.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.3 0.9 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.3 2.8 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.3 2.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 2.8 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.3 10.2 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.3 6.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.3 2.5 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.3 4.4 GO:0045475 locomotor rhythm(GO:0045475)
0.3 6.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.3 3.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 1.6 GO:0019732 antifungal humoral response(GO:0019732)
0.3 2.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.3 1.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3 1.9 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.3 1.3 GO:0051384 response to glucocorticoid(GO:0051384)
0.3 1.3 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.3 3.4 GO:0045008 depyrimidination(GO:0045008)
0.3 1.6 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.3 13.5 GO:0015701 bicarbonate transport(GO:0015701)
0.3 2.6 GO:0033327 Leydig cell differentiation(GO:0033327)
0.3 2.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.3 0.8 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.3 2.3 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.3 1.5 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.3 1.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 15.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 1.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 6.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.2 1.4 GO:0070383 DNA cytosine deamination(GO:0070383)
0.2 1.2 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.2 0.7 GO:1903413 cellular response to bile acid(GO:1903413)
0.2 0.7 GO:0009584 detection of visible light(GO:0009584)
0.2 4.6 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.2 1.8 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.2 1.8 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 0.7 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.2 0.9 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.2 1.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 0.4 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.2 4.6 GO:0045109 intermediate filament organization(GO:0045109)
0.2 0.7 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.2 17.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.2 5.3 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.2 3.7 GO:0007220 Notch receptor processing(GO:0007220)
0.2 0.6 GO:0034201 response to oleic acid(GO:0034201)
0.2 1.5 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.2 2.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.2 0.6 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.2 4.3 GO:0097186 amelogenesis(GO:0097186)
0.2 0.6 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.2 0.8 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415)
0.2 8.7 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.2 2.8 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.2 2.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 1.2 GO:0048102 autophagic cell death(GO:0048102)
0.2 3.7 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 5.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.2 3.7 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 5.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 1.1 GO:0006196 AMP catabolic process(GO:0006196)
0.2 1.9 GO:0030916 otic vesicle formation(GO:0030916)
0.2 0.9 GO:0051012 microtubule sliding(GO:0051012)
0.2 1.9 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 0.6 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.2 1.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 3.6 GO:0060325 face morphogenesis(GO:0060325)
0.2 1.8 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 1.8 GO:0060033 anatomical structure regression(GO:0060033)
0.2 1.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.6 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.2 2.8 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.2 0.7 GO:0035617 stress granule disassembly(GO:0035617)
0.2 4.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.5 GO:0042476 odontogenesis(GO:0042476)
0.2 0.7 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 0.2 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.2 1.7 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.2 1.7 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 1.5 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 0.7 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.2 0.5 GO:0051697 protein delipidation(GO:0051697)
0.2 16.3 GO:0007286 spermatid development(GO:0007286)
0.2 5.3 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.2 6.5 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.2 0.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 6.1 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.1 1.3 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 1.5 GO:0015871 choline transport(GO:0015871)
0.1 2.9 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 3.1 GO:0045821 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.1 1.6 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.6 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 8.6 GO:0006953 acute-phase response(GO:0006953)
0.1 2.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 1.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.6 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 2.1 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.1 0.8 GO:0006591 ornithine metabolic process(GO:0006591)
0.1 0.3 GO:0072143 renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.1 1.7 GO:0015671 gas transport(GO:0015669) oxygen transport(GO:0015671)
0.1 1.4 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.1 5.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 1.4 GO:0010212 response to ionizing radiation(GO:0010212)
0.1 2.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 5.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 2.9 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 1.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 4.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.8 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 3.4 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.8 GO:0045794 negative regulation of cell volume(GO:0045794)
0.1 1.8 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 2.7 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 1.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.2 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 0.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 3.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 3.7 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.5 GO:0051601 exocyst localization(GO:0051601)
0.1 2.7 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 2.8 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.6 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 2.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 1.9 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 5.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 2.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 1.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 1.1 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.2 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.1 2.2 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 0.5 GO:2001256 negative regulation of mast cell activation involved in immune response(GO:0033007) negative regulation of mast cell degranulation(GO:0043305) regulation of store-operated calcium entry(GO:2001256)
0.1 1.8 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 1.0 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.5 GO:0080009 mRNA methylation(GO:0080009)
0.1 1.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.7 GO:0051451 myoblast migration(GO:0051451)
0.1 3.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.4 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 1.8 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.1 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 2.7 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 1.0 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 0.2 GO:0035989 tendon development(GO:0035989) negative regulation of gastrulation(GO:2000542)
0.1 0.7 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 1.0 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.3 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 3.0 GO:0051972 regulation of telomerase activity(GO:0051972)
0.1 0.6 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.1 3.3 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.0 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 1.5 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 3.5 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.1 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.4 GO:0030728 ovulation(GO:0030728)
0.1 0.8 GO:0045023 G0 to G1 transition(GO:0045023)
0.1 0.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.3 GO:0043931 ossification involved in bone maturation(GO:0043931)
0.1 1.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.5 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 0.1 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.1 1.2 GO:0006706 steroid catabolic process(GO:0006706)
0.1 0.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 0.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.9 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 1.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 4.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.0 GO:0060612 adipose tissue development(GO:0060612)
0.1 3.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 2.1 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.1 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.7 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 1.0 GO:0001502 cartilage condensation(GO:0001502)
0.1 4.4 GO:0005977 glycogen metabolic process(GO:0005977)
0.1 2.4 GO:0003407 neural retina development(GO:0003407)
0.1 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.3 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 1.4 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 1.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.2 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.7 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 1.1 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.7 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 1.2 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 2.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.5 GO:0015886 heme transport(GO:0015886)
0.0 1.2 GO:0030866 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 1.4 GO:1901186 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 3.2 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 2.3 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 1.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.9 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 1.1 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0048541 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146)
0.0 2.0 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.0 0.2 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.8 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.9 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 1.4 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.6 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.3 GO:0007625 grooming behavior(GO:0007625)
0.0 0.2 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 2.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.4 GO:0035418 protein localization to synapse(GO:0035418)
0.0 1.5 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 1.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.4 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.6 GO:0006476 protein deacetylation(GO:0006476)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.8 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.0 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.3 GO:0015698 inorganic anion transport(GO:0015698)
0.0 9.0 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.0 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.1 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 1.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.6 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.8 GO:0001764 neuron migration(GO:0001764)
0.0 0.6 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.8 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 46.7 GO:0042627 chylomicron(GO:0042627)
2.5 12.6 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
2.4 40.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
2.3 11.3 GO:0001652 granular component(GO:0001652)
2.3 9.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
2.1 33.7 GO:0097512 cardiac myofibril(GO:0097512)
2.0 14.0 GO:0001520 outer dense fiber(GO:0001520)
1.6 4.8 GO:0097679 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
1.5 4.6 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
1.5 10.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
1.3 9.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.3 3.9 GO:0060053 neurofilament cytoskeleton(GO:0060053)
1.3 6.3 GO:0031501 mannosyltransferase complex(GO:0031501)
1.2 20.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
1.2 20.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.0 3.9 GO:0070695 FHF complex(GO:0070695)
1.0 8.6 GO:0070652 HAUS complex(GO:0070652)
0.9 4.7 GO:0070847 core mediator complex(GO:0070847)
0.9 2.8 GO:0043159 acrosomal matrix(GO:0043159)
0.9 3.7 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.9 6.5 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) phagocytic vesicle lumen(GO:0097013)
0.9 12.5 GO:0070578 RISC-loading complex(GO:0070578)
0.9 7.1 GO:0036157 outer dynein arm(GO:0036157)
0.8 4.9 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.8 3.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.8 11.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.7 3.0 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.7 5.9 GO:0071439 clathrin complex(GO:0071439)
0.7 2.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.7 4.2 GO:0061617 MICOS complex(GO:0061617)
0.7 2.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.7 2.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.6 2.5 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.6 3.0 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.6 9.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.5 3.6 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.5 1.4 GO:0005607 laminin-2 complex(GO:0005607)
0.5 9.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4 2.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.4 7.7 GO:0097225 sperm midpiece(GO:0097225)
0.4 19.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.4 1.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.4 5.2 GO:0043194 axon initial segment(GO:0043194)
0.4 3.0 GO:0034706 sodium channel complex(GO:0034706)
0.4 1.5 GO:0070876 SOSS complex(GO:0070876)
0.4 16.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.3 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.3 3.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.3 3.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 0.6 GO:0070852 cell body fiber(GO:0070852)
0.3 3.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.3 0.9 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.3 1.8 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.3 3.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 3.3 GO:0005915 zonula adherens(GO:0005915)
0.3 3.8 GO:0035102 PRC1 complex(GO:0035102)
0.3 2.1 GO:0000322 storage vacuole(GO:0000322)
0.3 11.7 GO:0032590 dendrite membrane(GO:0032590)
0.3 2.1 GO:0044294 dendritic growth cone(GO:0044294)
0.3 3.1 GO:0000800 lateral element(GO:0000800)
0.2 2.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 1.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 3.4 GO:0036038 MKS complex(GO:0036038)
0.2 0.7 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 1.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 1.8 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 2.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 1.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 11.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 2.2 GO:0035253 ciliary rootlet(GO:0035253)
0.2 3.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.2 1.3 GO:0030061 mitochondrial crista(GO:0030061)
0.2 2.6 GO:0044295 axonal growth cone(GO:0044295)
0.2 6.6 GO:0043198 dendritic shaft(GO:0043198)
0.2 1.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 3.2 GO:0005861 troponin complex(GO:0005861)
0.2 3.8 GO:0071564 npBAF complex(GO:0071564)
0.2 1.4 GO:0061574 ASAP complex(GO:0061574)
0.2 0.5 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2 1.2 GO:0005593 FACIT collagen trimer(GO:0005593)
0.2 36.5 GO:0001726 ruffle(GO:0001726)
0.2 3.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 5.5 GO:0016528 sarcoplasm(GO:0016528)
0.1 5.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.0 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.6 GO:0043293 apoptosome(GO:0043293)
0.1 2.1 GO:0051233 spindle midzone(GO:0051233)
0.1 0.4 GO:0016938 kinesin I complex(GO:0016938)
0.1 2.9 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 2.3 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.8 GO:0034464 BBSome(GO:0034464)
0.1 3.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 2.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 4.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 3.7 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.1 11.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 4.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.6 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 9.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 4.3 GO:0045095 keratin filament(GO:0045095)
0.1 4.5 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.8 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 2.3 GO:0001772 immunological synapse(GO:0001772)
0.1 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.1 5.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.1 GO:0042629 mast cell granule(GO:0042629)
0.1 1.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.5 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 2.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.9 GO:0005901 caveola(GO:0005901)
0.1 1.6 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.1 4.1 GO:0036064 ciliary basal body(GO:0036064)
0.1 6.0 GO:0035580 specific granule lumen(GO:0035580)
0.1 6.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.6 GO:0005796 Golgi lumen(GO:0005796)
0.1 6.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 4.9 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 2.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 2.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.1 1.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 2.4 GO:0001533 cornified envelope(GO:0001533)
0.1 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 3.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 4.2 GO:0005802 trans-Golgi network(GO:0005802)
0.1 3.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 2.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 1.0 GO:0042101 T cell receptor complex(GO:0042101)
0.0 10.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 5.5 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 3.4 GO:0005776 autophagosome(GO:0005776)
0.0 2.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.5 GO:0005903 brush border(GO:0005903)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.8 GO:0016235 aggresome(GO:0016235)
0.0 1.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.7 GO:0043204 perikaryon(GO:0043204)
0.0 3.0 GO:0030426 growth cone(GO:0030426)
0.0 3.8 GO:0044306 neuron projection terminus(GO:0044306)
0.0 2.7 GO:0043197 dendritic spine(GO:0043197)
0.0 2.1 GO:0005604 basement membrane(GO:0005604)
0.0 13.1 GO:0045202 synapse(GO:0045202)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 2.7 GO:0030424 axon(GO:0030424)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 5.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 4.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 1.9 GO:0043235 receptor complex(GO:0043235)
0.0 0.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 21.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
6.4 50.8 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
2.3 9.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
2.2 9.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
2.0 10.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
1.9 7.7 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
1.9 15.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.9 5.7 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
1.8 9.2 GO:0042289 MHC class II protein binding(GO:0042289)
1.8 36.4 GO:0051787 misfolded protein binding(GO:0051787)
1.8 12.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
1.8 10.5 GO:0042577 lipid phosphatase activity(GO:0042577)
1.7 6.9 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.6 6.3 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
1.5 3.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.5 9.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.4 12.8 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
1.3 4.0 GO:0070538 oleic acid binding(GO:0070538)
1.3 3.8 GO:0032093 SAM domain binding(GO:0032093)
1.2 4.9 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
1.1 14.7 GO:0019957 C-C chemokine binding(GO:0019957)
1.1 6.8 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
1.1 3.3 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.1 3.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.0 3.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
1.0 2.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.0 2.9 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
1.0 4.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.9 2.8 GO:0004040 amidase activity(GO:0004040) fucose binding(GO:0042806)
0.9 0.9 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.9 3.7 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.9 27.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.9 3.6 GO:0031716 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.9 5.3 GO:0048039 ubiquinone binding(GO:0048039)
0.9 3.4 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.9 3.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.8 4.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.8 14.3 GO:0038191 neuropilin binding(GO:0038191)
0.8 2.5 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.8 4.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.8 8.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.8 2.4 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.8 3.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.8 7.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.8 3.2 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.8 3.8 GO:0004771 sterol esterase activity(GO:0004771)
0.7 4.5 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.7 2.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.7 2.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.7 2.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.7 5.0 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.7 2.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.7 2.0 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.7 2.6 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.6 2.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.6 2.5 GO:0016160 amylase activity(GO:0016160)
0.6 2.5 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.6 4.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.6 4.9 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.6 1.8 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.6 2.4 GO:0035939 microsatellite binding(GO:0035939)
0.6 4.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.6 1.7 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.6 2.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5 4.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.5 6.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.5 7.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.5 4.2 GO:0005497 androgen binding(GO:0005497)
0.5 8.3 GO:0015250 water channel activity(GO:0015250)
0.5 5.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.5 1.5 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.5 1.5 GO:0098770 FBXO family protein binding(GO:0098770)
0.5 6.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.5 2.4 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.5 8.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.5 5.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.5 1.4 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.5 6.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.5 3.2 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.4 8.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.4 2.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.4 1.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.4 9.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.4 3.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.4 3.0 GO:0070573 metallodipeptidase activity(GO:0070573)
0.4 5.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.4 1.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.4 4.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.4 4.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 12.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 6.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.4 7.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.4 18.6 GO:0030507 spectrin binding(GO:0030507)
0.4 7.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4 1.9 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.4 1.5 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.4 10.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.4 19.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.4 1.8 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 1.0 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.3 3.8 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.3 1.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 0.7 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.3 4.7 GO:0030957 Tat protein binding(GO:0030957)
0.3 33.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 1.0 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.3 6.0 GO:0004622 lysophospholipase activity(GO:0004622)
0.3 1.0 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.3 2.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.3 1.9 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3 1.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.3 5.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 1.3 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.3 6.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.3 13.6 GO:0005158 insulin receptor binding(GO:0005158)
0.3 0.9 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.3 2.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 5.1 GO:0031005 filamin binding(GO:0031005)
0.3 8.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 3.3 GO:0004875 complement receptor activity(GO:0004875)
0.3 1.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.3 4.0 GO:0000030 mannosyltransferase activity(GO:0000030)
0.3 0.9 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.3 1.4 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.3 6.2 GO:0035198 miRNA binding(GO:0035198)
0.3 0.8 GO:0019961 interferon binding(GO:0019961)
0.3 11.7 GO:0015485 cholesterol binding(GO:0015485)
0.3 0.8 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 4.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.3 17.0 GO:0070063 RNA polymerase binding(GO:0070063)
0.3 7.4 GO:0005521 lamin binding(GO:0005521)
0.3 5.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 3.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 2.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 1.5 GO:0039552 RIG-I binding(GO:0039552)
0.2 2.2 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.7 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.2 4.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 0.9 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 0.7 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.2 3.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 0.6 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 2.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2 1.2 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.2 1.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 1.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 1.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.2 1.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 2.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 5.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 4.4 GO:0050780 dopamine receptor binding(GO:0050780)
0.2 1.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 3.2 GO:0043295 glutathione binding(GO:0043295)
0.2 1.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 1.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 1.3 GO:0042169 SH2 domain binding(GO:0042169)
0.2 1.8 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.2 1.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 2.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 0.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 0.7 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.2 7.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 1.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 1.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 5.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.2 2.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 1.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.2 0.5 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2 0.8 GO:0097157 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) pre-mRNA intronic binding(GO:0097157)
0.2 3.1 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 1.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 2.9 GO:0016805 dipeptidase activity(GO:0016805)
0.2 2.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 3.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 4.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.8 GO:0048185 activin binding(GO:0048185)
0.1 1.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 15.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 1.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 2.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 1.3 GO:0031433 telethonin binding(GO:0031433)
0.1 1.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 2.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 1.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 5.3 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 6.6 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.1 0.7 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 1.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.5 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 3.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 2.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 12.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.0 GO:0019864 IgG binding(GO:0019864)
0.1 1.5 GO:0070700 BMP receptor binding(GO:0070700)
0.1 18.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 2.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 0.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 2.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.6 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.6 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 1.6 GO:0016918 retinal binding(GO:0016918)
0.1 4.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 2.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 2.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.6 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 3.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 2.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 1.6 GO:0044548 S100 protein binding(GO:0044548)
0.1 3.3 GO:0030332 cyclin binding(GO:0030332)
0.1 2.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 9.4 GO:0044325 ion channel binding(GO:0044325)
0.1 0.9 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 2.3 GO:0043236 laminin binding(GO:0043236)
0.1 1.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 2.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 7.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 15.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 2.1 GO:0030371 translation repressor activity(GO:0030371)
0.1 1.1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 0.3 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 1.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 5.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.6 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.1 0.6 GO:0043028 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 1.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 4.1 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.1 5.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 2.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.4 GO:0008066 glutamate receptor activity(GO:0008066)
0.0 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 8.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.0 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.8 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.0 1.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 2.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 3.7 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 2.2 GO:0017022 myosin binding(GO:0017022)
0.0 2.6 GO:0019955 cytokine binding(GO:0019955)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 6.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0016917 GABA receptor activity(GO:0016917)
0.0 0.8 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.0 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 1.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.1 GO:0019843 rRNA binding(GO:0019843)
0.0 2.5 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.0 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.1 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0048487 beta-tubulin binding(GO:0048487)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.7 1.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.5 3.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.4 22.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.4 9.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 6.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.3 47.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.3 11.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.3 0.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.3 0.8 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 9.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.3 13.4 PID IFNG PATHWAY IFN-gamma pathway
0.2 2.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 4.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 4.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 0.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 3.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 9.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 1.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 4.9 PID SHP2 PATHWAY SHP2 signaling
0.2 5.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.2 8.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 6.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 0.6 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.2 4.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 6.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 2.9 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 4.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 6.8 PID BARD1 PATHWAY BARD1 signaling events
0.1 4.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 4.8 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 3.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 8.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 20.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 3.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 2.3 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 1.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 4.0 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 5.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 0.9 PID REELIN PATHWAY Reelin signaling pathway
0.1 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.7 PID RAS PATHWAY Regulation of Ras family activation
0.1 5.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 0.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 2.3 PID ARF6 PATHWAY Arf6 signaling events
0.1 3.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 2.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 2.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 2.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 12.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 0.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 3.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 5.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 3.6 REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR Genes involved in Downstream signaling of activated FGFR
1.6 6.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
1.4 6.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.1 2.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.9 0.9 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.9 12.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.8 27.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.8 1.6 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.6 17.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.5 2.2 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.4 12.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4 5.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.4 9.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 5.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.4 10.0 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.4 5.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 9.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 7.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 5.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 3.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.3 0.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 6.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.3 39.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 10.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 3.7 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.2 4.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 4.2 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.2 21.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 7.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 3.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 6.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 3.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 6.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 3.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 5.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 10.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 2.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 1.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 4.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 4.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 3.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 4.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 0.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 5.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 5.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 3.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 5.2 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 7.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.1 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1 6.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 2.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.0 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 1.8 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 8.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.6 REACTOME DEFENSINS Genes involved in Defensins
0.1 1.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 4.6 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 1.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 5.9 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 8.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 9.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.0 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 2.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 4.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.8 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 2.7 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 2.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.7 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.9 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 6.1 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 4.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 2.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.0 0.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 2.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion