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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GLIS1

Z-value: 0.28

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Transcription factors associated with GLIS1

Gene Symbol Gene ID Gene Info
ENSG00000174332.3 GLIS family zinc finger 1

Activity profile of GLIS1 motif

Sorted Z-values of GLIS1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_190992087 5.14 ENST00000553598.1
double homeobox 4 like 7
chr19_-_49828438 4.14 ENST00000454748.3
ENST00000598828.1
ENST00000335875.4
solute carrier family 6, member 16
chr4_+_191008560 3.64 ENST00000554690.1
double homeobox 4 like 3
chr4_+_190995380 3.43 ENST00000555191.1
double homeobox 4 like 6
chr4_+_191001979 3.16 ENST00000538692.1
double homeobox 4 like 4
chr4_+_191005267 3.10 ENST00000556625.1
double homeobox 4
chr4_+_191011860 3.10 ENST00000440426.1
double homeobox 4 like 2
chr4_+_190998673 3.02 ENST00000554668.1
double homeobox 4 like 5
chr19_+_40697514 2.05 ENST00000253055.3
mitogen-activated protein kinase kinase kinase 10
chr11_+_66886717 1.88 ENST00000398645.2
lysine (K)-specific demethylase 2A
chr11_+_68671310 1.72 ENST00000255078.3
ENST00000539224.1
immunoglobulin mu binding protein 2
chr18_+_11751466 1.28 ENST00000535121.1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr16_+_58059470 0.60 ENST00000219271.3
matrix metallopeptidase 15 (membrane-inserted)

Network of associatons between targets according to the STRING database.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.3 2.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.9 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 4.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.5 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 1.7 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.6 GO:0035987 endodermal cell differentiation(GO:0035987)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0032797 SMN complex(GO:0032797)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 1.7 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 1.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 4.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix