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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GTF2I

Z-value: 0.97

Motif logo

Transcription factors associated with GTF2I

Gene Symbol Gene ID Gene Info
ENSG00000077809.8 general transcription factor IIi

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GTF2Ihg19_v2_chr7_+_74072011_740721190.441.4e-11Click!

Activity profile of GTF2I motif

Sorted Z-values of GTF2I motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_23775971 14.92 ENST00000250405.5
BCL2-like 2
chr1_+_169075554 13.63 ENST00000367815.4
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_+_169077172 13.28 ENST00000499679.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr15_-_37392703 12.90 ENST00000382766.2
ENST00000444725.1
Meis homeobox 2
chrX_+_102631844 10.65 ENST00000372634.1
ENST00000299872.7
nerve growth factor receptor (TNFRSF16) associated protein 1
chr22_-_36236265 10.16 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_-_20812690 10.06 ENST00000375078.3
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr4_-_16900242 9.76 ENST00000502640.1
ENST00000506732.1
LIM domain binding 2
chr12_-_16759711 9.62 ENST00000447609.1
LIM domain only 3 (rhombotin-like 2)
chr12_-_45270151 8.98 ENST00000429094.2
NEL-like 2 (chicken)
chr5_+_92919043 8.64 ENST00000327111.3
nuclear receptor subfamily 2, group F, member 1
chr12_-_45270077 8.60 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chr4_-_16900410 8.59 ENST00000304523.5
LIM domain binding 2
chr6_-_29600832 8.09 ENST00000377016.4
ENST00000376977.3
ENST00000377034.4
gamma-aminobutyric acid (GABA) B receptor, 1
chr4_-_16900217 8.05 ENST00000441778.2
LIM domain binding 2
chr15_-_37392086 7.85 ENST00000561208.1
Meis homeobox 2
chr1_+_164528866 7.69 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr8_+_26371763 7.69 ENST00000521913.1
dihydropyrimidinase-like 2
chr2_+_159313452 7.61 ENST00000389757.3
ENST00000389759.3
plakophilin 4
chr8_-_30670053 7.56 ENST00000518564.1
protein phosphatase 2, catalytic subunit, beta isozyme
chr17_+_2496971 7.21 ENST00000397195.5
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr4_-_16900184 6.98 ENST00000515064.1
LIM domain binding 2
chr15_-_73925651 6.90 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
neuroplastin
chr7_+_69064300 6.88 ENST00000342771.4
autism susceptibility candidate 2
chr1_-_68698222 6.69 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
wntless Wnt ligand secretion mediator
chrX_-_134156502 6.55 ENST00000391440.1
family with sequence similarity 127, member C
chr5_+_138629389 6.54 ENST00000504045.1
ENST00000504311.1
ENST00000502499.1
matrin 3
chr6_+_30852130 6.39 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
discoidin domain receptor tyrosine kinase 1
chr2_+_54683419 6.26 ENST00000356805.4
spectrin, beta, non-erythrocytic 1
chr4_-_176923483 6.11 ENST00000280187.7
ENST00000512509.1
glycoprotein M6A
chr19_+_35629702 6.07 ENST00000351325.4
FXYD domain containing ion transport regulator 1
chr1_-_95391315 5.88 ENST00000545882.1
ENST00000415017.1
calponin 3, acidic
chr13_-_36705425 5.82 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
doublecortin-like kinase 1
chr12_+_110718921 5.81 ENST00000308664.6
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr6_+_114178512 5.80 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr1_+_27022839 5.79 ENST00000457599.2
AT rich interactive domain 1A (SWI-like)
chrX_+_118370288 5.78 ENST00000535419.1
progesterone receptor membrane component 1
chr11_-_72385437 5.70 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
phosphodiesterase 2A, cGMP-stimulated
chr13_-_45150392 5.63 ENST00000501704.2
TSC22 domain family, member 1
chr7_+_100770328 5.50 ENST00000223095.4
ENST00000445463.2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr2_+_62933001 5.49 ENST00000263991.5
ENST00000354487.3
EH domain binding protein 1
chr19_+_35630022 5.47 ENST00000589209.1
FXYD domain containing ion transport regulator 1
chr11_-_125366089 5.21 ENST00000366139.3
ENST00000278919.3
fasciculation and elongation protein zeta 1 (zygin I)
chr14_-_60337684 5.13 ENST00000267484.5
reticulon 1
chr2_-_56150910 5.09 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
EGF containing fibulin-like extracellular matrix protein 1
chr5_+_138629417 5.02 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
matrin 3
chr6_+_43739697 5.00 ENST00000230480.6
vascular endothelial growth factor A
chr14_-_23822061 4.82 ENST00000397260.3
solute carrier family 22, member 17
chr1_+_160175117 4.79 ENST00000360472.4
phosphoprotein enriched in astrocytes 15
chrX_+_118370211 4.78 ENST00000217971.7
progesterone receptor membrane component 1
chr14_-_23822080 4.71 ENST00000397267.1
ENST00000354772.3
solute carrier family 22, member 17
chr8_+_97506033 4.70 ENST00000518385.1
syndecan 2
chr1_+_160175201 4.69 ENST00000368076.1
phosphoprotein enriched in astrocytes 15
chr7_+_121513143 4.69 ENST00000393386.2
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr1_+_87797351 4.68 ENST00000370542.1
LIM domain only 4
chr16_-_65155979 4.67 ENST00000562325.1
ENST00000268603.4
cadherin 11, type 2, OB-cadherin (osteoblast)
chr15_-_37393406 4.58 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr12_-_45269430 4.46 ENST00000395487.2
NEL-like 2 (chicken)
chr17_-_15165854 4.44 ENST00000395936.1
ENST00000395938.2
peripheral myelin protein 22
chr2_-_227664474 4.44 ENST00000305123.5
insulin receptor substrate 1
chr20_-_49547910 4.42 ENST00000396032.3
activity-dependent neuroprotector homeobox
chr1_+_64059332 4.35 ENST00000540265.1
phosphoglucomutase 1
chr5_+_138089100 4.35 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr14_-_103987679 4.33 ENST00000553610.1
creatine kinase, brain
chr2_+_182756615 4.31 ENST00000431877.2
ENST00000320370.7
sperm specific antigen 2
chr9_+_87284622 4.30 ENST00000395882.1
neurotrophic tyrosine kinase, receptor, type 2
chr1_-_244013384 4.30 ENST00000366539.1
v-akt murine thymoma viral oncogene homolog 3
chr1_+_86046433 4.27 ENST00000451137.2
cysteine-rich, angiogenic inducer, 61
chr4_-_157892498 4.26 ENST00000502773.1
platelet derived growth factor C
chr1_-_68299130 4.25 ENST00000370982.3
guanine nucleotide binding protein (G protein), gamma 12
chr8_+_104152922 4.22 ENST00000309982.5
ENST00000438105.2
ENST00000297574.6
brain and acute leukemia, cytoplasmic
chr4_+_41361616 4.22 ENST00000513024.1
LIM and calponin homology domains 1
chr5_+_138629337 4.20 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
matrin 3
chr14_-_21491305 4.16 ENST00000554531.1
NDRG family member 2
chr12_+_12870055 4.14 ENST00000228872.4
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr5_-_111092930 4.06 ENST00000257435.7
neuronal regeneration related protein
chr17_-_36891830 4.04 ENST00000578487.1
polycomb group ring finger 2
chr20_-_49547731 4.03 ENST00000396029.3
activity-dependent neuroprotector homeobox
chr1_+_166808692 4.03 ENST00000367876.4
pogo transposable element with KRAB domain
chr15_+_22892663 4.01 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
cytoplasmic FMR1 interacting protein 1
chr3_+_105085734 3.99 ENST00000306107.5
activated leukocyte cell adhesion molecule
chr2_-_39664405 3.99 ENST00000341681.5
ENST00000263881.3
mitogen-activated protein kinase kinase kinase kinase 3
chr12_+_107168342 3.98 ENST00000392837.4
RIC8 guanine nucleotide exchange factor B
chr14_+_32546485 3.91 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
Rho GTPase activating protein 5
chr3_+_115342159 3.90 ENST00000305124.6
growth associated protein 43
chr1_-_68698197 3.86 ENST00000370973.2
ENST00000370971.1
wntless Wnt ligand secretion mediator
chr20_+_10199468 3.85 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr3_+_105086056 3.83 ENST00000472644.2
activated leukocyte cell adhesion molecule
chr2_-_55277436 3.82 ENST00000354474.6
reticulon 4
chr9_+_133320301 3.82 ENST00000352480.5
argininosuccinate synthase 1
chr3_+_115342349 3.80 ENST00000393780.3
growth associated protein 43
chr5_+_140772381 3.79 ENST00000398604.2
protocadherin gamma subfamily A, 8
chr6_+_19837592 3.78 ENST00000378700.3
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr5_-_73936451 3.78 ENST00000537006.1
ectodermal-neural cortex 1 (with BTB domain)
chr1_+_10271674 3.76 ENST00000377086.1
kinesin family member 1B
chr7_+_6414128 3.73 ENST00000348035.4
ENST00000356142.4
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
chr9_+_137967366 3.64 ENST00000252854.4
olfactomedin 1
chr6_-_6007200 3.63 ENST00000244766.2
neuritin 1
chr6_-_52860171 3.60 ENST00000370963.4
glutathione S-transferase alpha 4
chr2_+_36582857 3.56 ENST00000280527.2
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr5_+_71403061 3.53 ENST00000512974.1
ENST00000296755.7
microtubule-associated protein 1B
chr10_-_15413035 3.53 ENST00000378116.4
ENST00000455654.1
family with sequence similarity 171, member A1
chr19_-_49149553 3.48 ENST00000084798.4
carbonic anhydrase XI
chr6_-_52859968 3.47 ENST00000370959.1
glutathione S-transferase alpha 4
chr9_+_126773880 3.45 ENST00000373615.4
LIM homeobox 2
chr16_+_15528332 3.43 ENST00000566490.1
chromosome 16 open reading frame 45
chr19_+_40854559 3.42 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
phospholipase D family, member 3
chr1_-_87380002 3.41 ENST00000331835.5
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr17_+_45727204 3.40 ENST00000290158.4
karyopherin (importin) beta 1
chr5_-_111093167 3.40 ENST00000446294.2
ENST00000419114.2
neuronal regeneration related protein
chr9_-_139940608 3.38 ENST00000371601.4
neural proliferation, differentiation and control, 1
chr11_+_63742050 3.38 ENST00000314133.3
ENST00000535431.1
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr18_+_46065393 3.35 ENST00000256413.3
CBP80/20-dependent translation initiation factor
chr1_+_64058939 3.31 ENST00000371084.3
phosphoglucomutase 1
chr19_-_2015699 3.31 ENST00000255608.4
BTB (POZ) domain containing 2
chr14_+_32546274 3.28 ENST00000396582.2
Rho GTPase activating protein 5
chr2_-_200322723 3.27 ENST00000417098.1
SATB homeobox 2
chr17_-_1303462 3.23 ENST00000573026.1
ENST00000575977.1
ENST00000571732.1
ENST00000264335.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
chr15_+_49170083 3.21 ENST00000530028.2
EP300 interacting inhibitor of differentiation 1
chr2_-_55277692 3.21 ENST00000394611.2
reticulon 4
chr12_+_56473628 3.20 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr17_+_35851570 3.19 ENST00000394386.1
dual specificity phosphatase 14
chr9_-_14314066 3.18 ENST00000397575.3
nuclear factor I/B
chr6_-_16761678 3.18 ENST00000244769.4
ENST00000436367.1
ataxin 1
chr6_+_30850697 3.15 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
discoidin domain receptor tyrosine kinase 1
chr2_-_55277654 3.15 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
reticulon 4
chr20_+_34742650 3.14 ENST00000373945.1
ENST00000338074.2
erythrocyte membrane protein band 4.1-like 1
chr12_+_120933859 3.14 ENST00000242577.6
ENST00000548214.1
ENST00000392508.2
dynein, light chain, LC8-type 1
chr5_-_146833485 3.13 ENST00000398514.3
dihydropyrimidinase-like 3
chr11_+_2405833 3.13 ENST00000527343.1
ENST00000464784.2
CD81 molecule
chr16_+_56225248 3.12 ENST00000262493.6
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr4_+_41540160 3.12 ENST00000503057.1
ENST00000511496.1
LIM and calponin homology domains 1
chrX_+_54834791 3.11 ENST00000218439.4
ENST00000375058.1
ENST00000375060.1
melanoma antigen family D, 2
chr14_-_51562745 3.10 ENST00000298355.3
tripartite motif containing 9
chr12_+_120933904 3.09 ENST00000550178.1
ENST00000550845.1
ENST00000549989.1
ENST00000552870.1
dynein, light chain, LC8-type 1
chr15_+_41523335 3.08 ENST00000334660.5
calcineurin-like EF-hand protein 1
chr12_-_6484715 3.08 ENST00000228916.2
sodium channel, non-voltage-gated 1 alpha subunit
chrX_-_1511617 3.06 ENST00000381401.5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr7_+_98923505 3.06 ENST00000432884.2
ENST00000262942.5
actin related protein 2/3 complex, subunit 1A, 41kDa
chr4_-_102268484 3.05 ENST00000394853.4
protein phosphatase 3, catalytic subunit, alpha isozyme
chr10_+_74033672 3.04 ENST00000307365.3
DNA-damage-inducible transcript 4
chr2_-_74601758 3.02 ENST00000407639.2
ENST00000409438.1
dynactin 1
chr2_-_55277512 3.00 ENST00000402434.2
reticulon 4
chr6_-_33385854 2.99 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr11_+_75273246 2.98 ENST00000526397.1
ENST00000529643.1
ENST00000525492.1
ENST00000530284.1
ENST00000532356.1
ENST00000524558.1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr9_-_14314566 2.98 ENST00000397579.2
nuclear factor I/B
chr12_+_6833237 2.98 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
COP9 signalosome subunit 7A
chr3_+_11034403 2.96 ENST00000287766.4
ENST00000425938.1
solute carrier family 6 (neurotransmitter transporter), member 1
chr2_+_198365095 2.94 ENST00000409468.1
heat shock 10kDa protein 1
chr6_-_47277634 2.92 ENST00000296861.2
tumor necrosis factor receptor superfamily, member 21
chr10_+_114709999 2.91 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chrX_+_56590002 2.89 ENST00000338222.5
ubiquilin 2
chr12_-_115121962 2.87 ENST00000349155.2
T-box 3
chr16_-_65155833 2.87 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_+_223889285 2.87 ENST00000433674.2
calpain 2, (m/II) large subunit
chr19_-_39330818 2.87 ENST00000594769.1
ENST00000602021.1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
chr1_+_205473720 2.85 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
cyclin-dependent kinase 18
chr19_+_56152262 2.84 ENST00000325333.5
ENST00000590190.1
zinc finger protein 580
chr1_+_77747656 2.84 ENST00000354567.2
adenylate kinase 5
chr2_-_50574856 2.84 ENST00000342183.5
neurexin 1
chr9_-_14314518 2.83 ENST00000397581.2
nuclear factor I/B
chr16_+_8768422 2.83 ENST00000268251.8
ENST00000564714.1
4-aminobutyrate aminotransferase
chr9_+_71789081 2.82 ENST00000377245.4
tight junction protein 2
chr14_-_21492113 2.80 ENST00000554094.1
NDRG family member 2
chr1_-_113247543 2.79 ENST00000414971.1
ENST00000534717.1
ras homolog family member C
chr4_-_102268628 2.79 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
protein phosphatase 3, catalytic subunit, alpha isozyme
chr16_-_29910853 2.78 ENST00000308713.5
seizure related 6 homolog (mouse)-like 2
chr13_-_67804445 2.78 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
protocadherin 9
chr17_+_37026284 2.77 ENST00000433206.2
ENST00000435347.3
LIM and SH3 protein 1
chr11_-_64410787 2.75 ENST00000301894.2
neurexin 2
chr4_-_74124502 2.75 ENST00000358602.4
ENST00000330838.6
ENST00000561029.1
ankyrin repeat domain 17
chr7_-_23510086 2.75 ENST00000258729.3
insulin-like growth factor 2 mRNA binding protein 3
chr11_+_75273101 2.75 ENST00000533603.1
ENST00000358171.3
ENST00000526242.1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr5_+_125758813 2.75 ENST00000285689.3
ENST00000515200.1
GRAM domain containing 3
chr12_+_110719032 2.74 ENST00000395494.2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr5_+_173472607 2.74 ENST00000303177.3
ENST00000519867.1
Neuron-specific protein family member 2
chr3_-_168864427 2.73 ENST00000468789.1
MDS1 and EVI1 complex locus
chr6_-_56819385 2.73 ENST00000370754.5
ENST00000449297.2
dystonin
chr6_-_33385870 2.72 ENST00000488034.1
cutA divalent cation tolerance homolog (E. coli)
chr12_-_53893399 2.72 ENST00000267079.2
mitogen-activated protein kinase kinase kinase 12
chr9_+_71789133 2.69 ENST00000348208.4
ENST00000265384.7
tight junction protein 2
chr2_+_8822113 2.69 ENST00000396290.1
ENST00000331129.3
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr20_+_44035847 2.68 ENST00000372712.2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr2_-_47403642 2.68 ENST00000456319.1
ENST00000409563.1
ENST00000272298.7
calmodulin 2 (phosphorylase kinase, delta)
chr2_-_152684977 2.65 ENST00000428992.2
ENST00000295087.8
ADP-ribosylation factor-like 5A
chr7_+_134551583 2.65 ENST00000435928.1
caldesmon 1
chr8_+_104513086 2.65 ENST00000406091.3
regulating synaptic membrane exocytosis 2
chr6_-_33385655 2.65 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr20_+_57427765 2.63 ENST00000371100.4
GNAS complex locus
chr3_-_134093275 2.63 ENST00000513145.1
ENST00000422605.2
angiomotin like 2
chr10_-_62493223 2.63 ENST00000373827.2
ankyrin 3, node of Ranvier (ankyrin G)
chr5_+_125758865 2.62 ENST00000542322.1
ENST00000544396.1
GRAM domain containing 3
chr22_-_39639021 2.62 ENST00000455790.1
platelet-derived growth factor beta polypeptide
chr7_+_30951461 2.62 ENST00000311813.4
aquaporin 1 (Colton blood group)
chr3_+_183894566 2.62 ENST00000439647.1
adaptor-related protein complex 2, mu 1 subunit
chr7_+_65552756 2.60 ENST00000450043.1
AC068533.7
chr12_-_16761007 2.58 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr19_-_6502590 2.57 ENST00000264071.2
tubulin, beta 4A class IVa
chr1_+_160085501 2.56 ENST00000361216.3
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr11_+_62475130 2.54 ENST00000294117.5
guanine nucleotide binding protein (G protein), gamma 3

Network of associatons between targets according to the STRING database.

First level regulatory network of GTF2I

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 26.9 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
3.5 10.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
2.9 8.6 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
2.8 13.8 GO:1903275 regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
2.7 8.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
2.1 10.7 GO:1904274 tricellular tight junction assembly(GO:1904274)
2.0 12.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.9 5.8 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
1.9 9.5 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.9 5.7 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
1.8 5.5 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
1.8 12.7 GO:0060011 Sertoli cell proliferation(GO:0060011)
1.7 15.6 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
1.7 6.9 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.7 5.0 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
1.6 9.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.6 9.5 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
1.6 22.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
1.6 6.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
1.6 6.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
1.5 9.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.5 10.6 GO:0021540 corpus callosum morphogenesis(GO:0021540)
1.5 2.9 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
1.4 4.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.4 4.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
1.3 4.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
1.3 9.0 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.3 6.3 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
1.3 3.8 GO:1904647 response to rotenone(GO:1904647)
1.2 3.7 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
1.2 8.5 GO:0033484 nitric oxide homeostasis(GO:0033484)
1.2 9.6 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.2 3.6 GO:0052031 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
1.2 4.6 GO:0010159 specification of organ position(GO:0010159)
1.2 1.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
1.2 4.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
1.1 29.4 GO:0010669 epithelial structure maintenance(GO:0010669)
1.1 3.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.1 3.2 GO:1904529 regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
1.0 4.2 GO:0031291 Ran protein signal transduction(GO:0031291)
1.0 4.1 GO:0048749 compound eye development(GO:0048749)
1.0 5.0 GO:1903976 negative regulation of glial cell migration(GO:1903976)
1.0 3.9 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.9 2.8 GO:0009183 ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.9 9.3 GO:0016198 axon choice point recognition(GO:0016198)
0.9 0.9 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.9 0.9 GO:0061386 closure of optic fissure(GO:0061386)
0.9 2.6 GO:0072019 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.9 5.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.8 2.5 GO:0021778 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.8 2.5 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.8 3.3 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.8 4.1 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.8 0.8 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.8 3.1 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.8 3.8 GO:0061107 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.7 3.0 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.7 2.9 GO:0003095 pressure natriuresis(GO:0003095)
0.7 2.9 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.7 7.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.7 6.4 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.7 4.3 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.7 5.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.7 2.8 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.7 0.7 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.7 2.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.7 3.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.7 4.7 GO:0008218 bioluminescence(GO:0008218)
0.7 4.7 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.7 2.0 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.7 2.6 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.7 2.0 GO:0035989 tendon development(GO:0035989)
0.7 2.6 GO:0072660 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.6 1.9 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.6 2.6 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.6 5.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.6 5.6 GO:0021978 telencephalon regionalization(GO:0021978)
0.6 3.7 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.6 0.6 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.6 6.6 GO:0045176 apical protein localization(GO:0045176)
0.6 7.7 GO:0019388 galactose catabolic process(GO:0019388)
0.6 1.7 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.6 4.6 GO:0003190 atrioventricular valve formation(GO:0003190)
0.6 1.7 GO:0048627 myoblast development(GO:0048627)
0.6 6.3 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.6 6.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.6 0.6 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.6 1.7 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.6 3.4 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.5 7.1 GO:0042659 regulation of cell fate specification(GO:0042659)
0.5 1.1 GO:0060166 olfactory pit development(GO:0060166)
0.5 8.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.5 1.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.5 5.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.5 2.1 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.5 2.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.5 2.1 GO:0090677 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.5 1.0 GO:0097327 response to antineoplastic agent(GO:0097327)
0.5 3.1 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.5 1.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.5 3.0 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.5 10.6 GO:0051764 actin crosslink formation(GO:0051764)
0.5 0.5 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.5 0.5 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.5 3.8 GO:0006526 arginine biosynthetic process(GO:0006526)
0.5 2.8 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.5 2.8 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.5 1.4 GO:0070295 renal water absorption(GO:0070295)
0.4 2.2 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.4 0.4 GO:0003162 atrioventricular node development(GO:0003162)
0.4 3.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.4 7.0 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.4 1.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.4 1.7 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.4 3.5 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.4 27.7 GO:0008542 visual learning(GO:0008542)
0.4 1.3 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.4 1.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.4 1.3 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.4 3.4 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.4 3.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.4 3.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 2.1 GO:1990910 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
0.4 1.2 GO:0006404 RNA import into nucleus(GO:0006404)
0.4 2.0 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) positive regulation of retinal ganglion cell axon guidance(GO:1902336) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.4 3.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.4 0.8 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.4 1.5 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.4 7.2 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.4 5.9 GO:0000338 protein deneddylation(GO:0000338)
0.4 1.8 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.4 1.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.4 7.3 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.4 1.4 GO:0043335 protein unfolding(GO:0043335)
0.4 1.8 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.3 3.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.3 2.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.3 2.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.3 1.7 GO:0030070 insulin processing(GO:0030070)
0.3 2.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.3 0.7 GO:1900238 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.3 2.0 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.3 6.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.3 1.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.3 0.7 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.3 3.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.3 1.0 GO:0060022 hard palate development(GO:0060022)
0.3 1.9 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 2.3 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.3 6.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.3 1.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.3 3.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.3 3.4 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.3 1.5 GO:0006543 glutamine catabolic process(GO:0006543)
0.3 1.8 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.3 3.5 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.3 6.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.3 0.9 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.3 0.3 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.3 1.2 GO:0042412 taurine biosynthetic process(GO:0042412)
0.3 2.9 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.3 2.9 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.3 1.1 GO:0002159 desmosome assembly(GO:0002159)
0.3 0.6 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.3 4.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.3 0.8 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.3 2.0 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.3 4.4 GO:0032060 bleb assembly(GO:0032060)
0.3 2.8 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.3 2.5 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.3 1.6 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.3 1.3 GO:0021759 globus pallidus development(GO:0021759)
0.3 2.4 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.3 2.7 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.3 1.3 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 2.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 2.1 GO:0006983 ER overload response(GO:0006983)
0.3 4.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.3 0.8 GO:0001554 luteolysis(GO:0001554)
0.3 0.8 GO:0021612 rhombomere 5 development(GO:0021571) facial nerve structural organization(GO:0021612)
0.3 0.8 GO:0035900 response to isolation stress(GO:0035900)
0.3 0.5 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.3 1.8 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 1.9 GO:0015693 magnesium ion transport(GO:0015693)
0.2 2.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 1.0 GO:0043489 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.2 0.7 GO:0061743 motor learning(GO:0061743)
0.2 1.6 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 0.5 GO:0043254 regulation of protein complex assembly(GO:0043254)
0.2 0.9 GO:0019046 release from viral latency(GO:0019046)
0.2 0.9 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2 0.2 GO:1904037 positive regulation of epithelial cell apoptotic process(GO:1904037)
0.2 2.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 0.5 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.2 0.7 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2 0.9 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.2 1.8 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 7.1 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.2 1.1 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.2 7.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 6.4 GO:0008104 protein localization(GO:0008104)
0.2 1.3 GO:0006012 galactose metabolic process(GO:0006012)
0.2 2.5 GO:0097062 dendritic spine maintenance(GO:0097062)
0.2 1.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2 1.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 5.0 GO:0061157 mRNA destabilization(GO:0061157)
0.2 3.7 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.2 1.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 1.0 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.8 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.2 3.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.2 0.6 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 1.2 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.2 1.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 1.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125) minus-end-directed organelle transport along microtubule(GO:0072385)
0.2 0.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 1.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.2 2.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 1.7 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 7.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.2 0.9 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.2 4.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 0.9 GO:0006449 regulation of translational termination(GO:0006449)
0.2 1.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 0.5 GO:1903412 response to bile acid(GO:1903412)
0.2 1.4 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.2 0.7 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.2 0.8 GO:0060356 leucine import(GO:0060356)
0.2 1.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.2 9.4 GO:0046677 response to antibiotic(GO:0046677)
0.2 1.0 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 5.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 0.3 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.2 2.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 7.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.2 1.1 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.2 0.5 GO:0031133 regulation of axon diameter(GO:0031133)
0.2 0.5 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.2 3.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 2.6 GO:0016540 protein autoprocessing(GO:0016540)
0.2 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2 0.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 0.8 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 0.9 GO:0006477 protein sulfation(GO:0006477)
0.2 0.5 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 2.8 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.2 1.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 1.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 1.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.7 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.6 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.7 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1 0.7 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.1 4.9 GO:0035329 hippo signaling(GO:0035329)
0.1 4.0 GO:0002076 osteoblast development(GO:0002076)
0.1 1.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.8 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.1 4.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 3.2 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 5.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 2.7 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.8 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 3.9 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 3.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.6 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 1.7 GO:0031103 axon regeneration(GO:0031103)
0.1 2.0 GO:0015800 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.1 1.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 2.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.7 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 1.1 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.6 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.7 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.8 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 1.1 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.3 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 0.4 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.1 0.3 GO:0032909 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.1 2.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 1.0 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 4.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.6 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 0.3 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 0.6 GO:0019050 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526) cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 1.5 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.1 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 1.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.8 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 2.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 1.6 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 1.3 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 3.2 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 1.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.9 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 2.8 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.1 0.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.4 GO:1902065 response to L-glutamate(GO:1902065)
0.1 5.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 1.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) regulation of glycogen (starch) synthase activity(GO:2000465) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 2.0 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 1.6 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 2.1 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.9 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.0 GO:0019915 lipid storage(GO:0019915)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.6 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.9 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 2.5 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.1 1.6 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 2.8 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.9 GO:0003091 renal water homeostasis(GO:0003091)
0.1 1.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.8 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.1 2.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.3 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.1 0.7 GO:0032264 IMP salvage(GO:0032264)
0.1 0.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.8 GO:1901741 regulation of myoblast fusion(GO:1901739) positive regulation of myoblast fusion(GO:1901741)
0.1 1.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.1 0.9 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 2.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.5 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 1.5 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 3.8 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 2.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 1.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 1.6 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.1 0.8 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 1.5 GO:0002369 T cell cytokine production(GO:0002369)
0.1 0.6 GO:0019724 immunoglobulin mediated immune response(GO:0016064) B cell mediated immunity(GO:0019724)
0.1 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426) retinal blood vessel morphogenesis(GO:0061304)
0.1 0.8 GO:0030252 growth hormone secretion(GO:0030252)
0.1 2.6 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 1.5 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.5 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 1.8 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.4 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.2 GO:0034442 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.4 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.0 1.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.8 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.3 GO:0050915 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) sensory perception of sour taste(GO:0050915)
0.0 0.6 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.6 GO:0007567 parturition(GO:0007567)
0.0 0.3 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.0 0.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.2 GO:1903242 regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0 2.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.0 GO:0030516 regulation of axon extension(GO:0030516)
0.0 0.2 GO:2000254 regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 2.0 GO:2001234 negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 1.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 1.0 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 1.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.3 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 2.0 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 5.2 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 3.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.7 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 1.6 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.4 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 1.2 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0098868 endochondral bone growth(GO:0003416) bone growth(GO:0098868)
0.0 0.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.3 GO:0051683 establishment of Golgi localization(GO:0051683) Golgi reassembly(GO:0090168)
0.0 0.5 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.9 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.1 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.5 GO:0042551 neuron maturation(GO:0042551)
0.0 0.2 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.4 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.4 GO:0002190 cap-independent translational initiation(GO:0002190) IRES-dependent translational initiation(GO:0002192)
0.0 0.1 GO:0097384 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129) cellular lipid biosynthetic process(GO:0097384)
0.0 1.1 GO:0072384 organelle transport along microtubule(GO:0072384)
0.0 0.8 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 0.5 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.9 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.3 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 2.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.0 GO:0048548 regulation of pinocytosis(GO:0048548) positive regulation of pinocytosis(GO:0048549) dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099) citrate metabolic process(GO:0006101)
0.0 0.6 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.0 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.4 GO:0051028 mRNA transport(GO:0051028)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.7 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 0.8 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.0 GO:0035646 endosome to melanosome transport(GO:0035646) pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.2 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.6 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.6 GO:0065002 intracellular protein transmembrane transport(GO:0065002)
0.0 0.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.2 GO:0009411 response to UV(GO:0009411)
0.0 0.6 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
2.2 44.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.9 5.6 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
1.8 10.7 GO:0061689 tricellular tight junction(GO:0061689)
1.6 4.7 GO:0072534 perineuronal net(GO:0072534)
1.1 7.7 GO:0032584 growth cone membrane(GO:0032584)
1.0 20.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
1.0 13.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
1.0 3.0 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
1.0 4.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.0 3.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.9 7.2 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.9 6.3 GO:0032437 cuticular plate(GO:0032437)
0.9 4.4 GO:0005899 insulin receptor complex(GO:0005899)
0.9 2.6 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.8 8.3 GO:0001739 sex chromatin(GO:0001739)
0.8 3.3 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.7 9.7 GO:0097470 ribbon synapse(GO:0097470)
0.7 6.2 GO:0005955 calcineurin complex(GO:0005955)
0.7 2.7 GO:0031673 H zone(GO:0031673)
0.7 13.3 GO:0044295 axonal growth cone(GO:0044295)
0.7 6.0 GO:0005915 zonula adherens(GO:0005915)
0.7 2.0 GO:0005588 collagen type V trimer(GO:0005588)
0.6 3.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.6 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.6 3.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.5 6.1 GO:0060077 inhibitory synapse(GO:0060077)
0.5 1.0 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.5 0.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.5 5.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.4 3.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.4 2.6 GO:0033269 internode region of axon(GO:0033269)
0.4 4.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.4 1.5 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.4 5.8 GO:0043073 germ cell nucleus(GO:0043073)
0.4 4.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.4 1.8 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.4 1.4 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.3 2.8 GO:0005587 collagen type IV trimer(GO:0005587)
0.3 1.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.3 11.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 3.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.3 8.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 15.6 GO:0008180 COP9 signalosome(GO:0008180)
0.3 9.0 GO:0030057 desmosome(GO:0030057)
0.3 3.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 1.8 GO:0072487 MSL complex(GO:0072487)
0.3 0.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 2.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 3.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 1.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.3 1.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 1.7 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.2 6.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.2 3.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 1.9 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 15.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 1.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 2.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 4.2 GO:0042627 chylomicron(GO:0042627)
0.2 4.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 2.5 GO:0005642 annulate lamellae(GO:0005642)
0.2 11.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 3.0 GO:0005869 dynactin complex(GO:0005869)
0.2 0.6 GO:0000798 nuclear cohesin complex(GO:0000798)
0.2 2.2 GO:0032797 SMN complex(GO:0032797)
0.2 10.9 GO:0042734 presynaptic membrane(GO:0042734)
0.2 3.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 1.9 GO:0043218 compact myelin(GO:0043218)
0.2 1.7 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 0.4 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 3.2 GO:0030056 hemidesmosome(GO:0030056)
0.2 30.1 GO:0030426 growth cone(GO:0030426)
0.2 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 0.7 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 2.7 GO:0030478 actin cap(GO:0030478)
0.2 3.9 GO:0034706 sodium channel complex(GO:0034706)
0.2 8.1 GO:0005871 kinesin complex(GO:0005871)
0.2 3.0 GO:0034399 nuclear periphery(GO:0034399)
0.2 1.7 GO:0071953 elastic fiber(GO:0071953)
0.2 1.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 0.6 GO:0036126 sperm flagellum(GO:0036126)
0.2 2.6 GO:0031143 pseudopodium(GO:0031143)
0.2 1.8 GO:0033270 paranode region of axon(GO:0033270)
0.2 1.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.2 0.5 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 40.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 1.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 1.8 GO:0033268 node of Ranvier(GO:0033268)
0.1 4.5 GO:0042101 T cell receptor complex(GO:0042101)
0.1 4.7 GO:0005685 U1 snRNP(GO:0005685)
0.1 17.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 2.0 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 4.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.8 GO:0032420 stereocilium(GO:0032420)
0.1 1.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 3.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.9 GO:0005638 lamin filament(GO:0005638)
0.1 2.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 2.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.8 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.1 1.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 2.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.7 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 1.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.7 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 1.5 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.6 GO:0098827 endoplasmic reticulum subcompartment(GO:0098827)
0.1 2.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.4 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.7 GO:0070852 cell body fiber(GO:0070852)
0.1 3.1 GO:0001772 immunological synapse(GO:0001772)
0.1 1.9 GO:0005605 basal lamina(GO:0005605)
0.1 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 9.2 GO:0005875 microtubule associated complex(GO:0005875)
0.1 6.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 4.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.4 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.5 GO:1990393 3M complex(GO:1990393)
0.1 1.4 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 1.4 GO:0000786 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.1 27.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 3.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.5 GO:0000145 exocyst(GO:0000145)
0.1 0.6 GO:0071203 WASH complex(GO:0071203)
0.1 31.6 GO:0031252 cell leading edge(GO:0031252)
0.1 0.9 GO:0045180 basal cortex(GO:0045180)
0.1 2.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 32.7 GO:0043025 neuronal cell body(GO:0043025)
0.1 5.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.4 GO:0030427 site of polarized growth(GO:0030427)
0.1 22.9 GO:0016324 apical plasma membrane(GO:0016324)
0.1 0.7 GO:0000125 PCAF complex(GO:0000125)
0.1 1.4 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.1 0.8 GO:0099738 cell cortex region(GO:0099738)
0.1 0.8 GO:0030914 STAGA complex(GO:0030914)
0.1 4.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.2 GO:0032433 filopodium tip(GO:0032433)
0.1 0.7 GO:0044754 autolysosome(GO:0044754)
0.1 0.7 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 1.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 0.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 13.3 GO:0031301 integral component of organelle membrane(GO:0031301)
0.1 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.4 GO:0002102 podosome(GO:0002102)
0.1 0.4 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.8 GO:1990752 microtubule end(GO:1990752)
0.1 0.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.7 GO:0005903 brush border(GO:0005903)
0.1 1.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 1.9 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 3.1 GO:0005811 lipid particle(GO:0005811)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0031201 SNARE complex(GO:0031201)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 2.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 5.1 GO:0030424 axon(GO:0030424)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.2 GO:0045177 apical part of cell(GO:0045177)
0.0 2.2 GO:0098793 presynapse(GO:0098793)
0.0 3.3 GO:0030133 transport vesicle(GO:0030133)
0.0 3.5 GO:0043209 myelin sheath(GO:0043209)
0.0 12.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 2.8 GO:0005938 cell cortex(GO:0005938)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)
0.0 2.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.5 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 16.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.7 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.0 GO:1990904 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.0 2.0 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 1.7 GO:0005840 ribosome(GO:0005840)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 5.3 GO:0019866 organelle inner membrane(GO:0019866)
0.0 5.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0019867 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 1.0 GO:0010008 endosome membrane(GO:0010008)
0.0 0.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
2.6 7.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
2.5 27.3 GO:0030274 LIM domain binding(GO:0030274)
2.0 10.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.8 29.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.8 7.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.8 10.7 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
1.5 4.6 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
1.4 5.6 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
1.3 7.7 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.2 15.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
1.0 5.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.0 3.9 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.9 5.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.9 5.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.9 0.9 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.9 2.6 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.9 3.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.8 3.3 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.8 5.0 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.8 6.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.8 2.5 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.8 4.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.8 4.9 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.8 4.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.8 3.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.8 7.7 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.8 10.6 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.7 5.9 GO:0004111 creatine kinase activity(GO:0004111)
0.7 2.9 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.7 13.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.7 5.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.7 2.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.7 13.3 GO:0051400 BH domain binding(GO:0051400)
0.6 3.2 GO:0034046 poly(G) binding(GO:0034046)
0.6 1.8 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.6 3.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6 1.7 GO:0005047 signal recognition particle binding(GO:0005047)
0.6 3.9 GO:0050815 phosphoserine binding(GO:0050815)
0.6 3.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.6 2.8 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.5 1.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.5 1.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.5 3.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.5 2.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.5 4.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.5 3.0 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.5 1.9 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.4 2.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.4 4.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.4 2.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.4 2.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.4 2.8 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.4 5.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 5.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.4 1.5 GO:0005046 KDEL sequence binding(GO:0005046)
0.4 7.8 GO:0044548 S100 protein binding(GO:0044548)
0.4 1.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.4 4.8 GO:0038132 neuregulin binding(GO:0038132)
0.4 3.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 1.8 GO:0050816 phosphothreonine binding(GO:0050816)
0.3 1.0 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.3 4.1 GO:0042301 phosphate ion binding(GO:0042301)
0.3 1.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.3 1.0 GO:0015616 DNA translocase activity(GO:0015616)
0.3 3.9 GO:1990459 transferrin receptor binding(GO:1990459)
0.3 1.9 GO:0043237 laminin-1 binding(GO:0043237)
0.3 3.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 1.3 GO:0035473 lipase binding(GO:0035473)
0.3 3.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 8.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 1.5 GO:0004359 glutaminase activity(GO:0004359)
0.3 2.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 1.8 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.3 4.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 7.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 1.2 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.3 22.4 GO:0005507 copper ion binding(GO:0005507)
0.3 0.8 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.3 13.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 3.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 14.6 GO:0005080 protein kinase C binding(GO:0005080)
0.3 3.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 5.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 6.6 GO:0030506 ankyrin binding(GO:0030506)
0.3 1.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.3 0.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 0.8 GO:0048030 disaccharide binding(GO:0048030)
0.3 0.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.3 1.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 2.5 GO:0042731 PH domain binding(GO:0042731)
0.2 1.7 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 1.0 GO:0035939 microsatellite binding(GO:0035939)
0.2 3.9 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 4.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 1.7 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.2 1.2 GO:0005534 galactose binding(GO:0005534)
0.2 1.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.7 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.2 1.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2 0.7 GO:0017129 triglyceride binding(GO:0017129)
0.2 5.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 7.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 2.6 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 1.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 3.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 3.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 1.4 GO:0030911 TPR domain binding(GO:0030911)
0.2 0.8 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 2.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 1.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 4.3 GO:0043236 laminin binding(GO:0043236)
0.2 0.8 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2 1.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 1.0 GO:0008494 translation activator activity(GO:0008494)
0.2 2.4 GO:0033691 sialic acid binding(GO:0033691)
0.2 1.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 1.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 4.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 1.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 3.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 1.2 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 1.5 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.2 3.5 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.2 2.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 7.4 GO:0042169 SH2 domain binding(GO:0042169)
0.2 4.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 0.2 GO:0031433 telethonin binding(GO:0031433)
0.2 0.9 GO:0098821 BMP receptor activity(GO:0098821)
0.2 2.0 GO:0031005 filamin binding(GO:0031005)
0.2 0.9 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 1.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 0.9 GO:0043532 angiostatin binding(GO:0043532)
0.2 1.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.2 2.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 7.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 1.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 1.0 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 3.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.8 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 3.0 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.7 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 3.4 GO:0005521 lamin binding(GO:0005521)
0.1 0.4 GO:0086078 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.1 0.5 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 1.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 1.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 8.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 2.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.5 GO:0004461 lactose synthase activity(GO:0004461)
0.1 2.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.4 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.9 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.6 GO:0035497 cAMP response element binding(GO:0035497)
0.1 4.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 3.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.7 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 1.4 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 34.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 0.7 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.9 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 4.0 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.1 3.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 2.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 3.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 2.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.4 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 10.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 4.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.4 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 2.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 5.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.5 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 2.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 2.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.8 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 3.7 GO:0030507 spectrin binding(GO:0030507)
0.1 1.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 1.2 GO:0000339 RNA cap binding(GO:0000339)
0.1 1.1 GO:0031386 protein tag(GO:0031386)
0.1 0.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.4 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 1.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.4 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.1 4.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 3.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 2.2 GO:0042056 chemoattractant activity(GO:0042056)
0.1 29.4 GO:0045296 cadherin binding(GO:0045296)
0.1 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 2.2 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.6 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.1 0.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 2.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.8 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1 0.5 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 0.3 GO:0045118 azole transporter activity(GO:0045118)
0.1 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.5 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.2 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 3.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 5.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 2.6 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.8 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.4 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 4.9 GO:0020037 heme binding(GO:0020037)
0.0 3.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 20.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.0 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 8.3 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 3.2 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 12.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 4.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0043199 sulfate binding(GO:0043199)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0005319 lipid transporter activity(GO:0005319)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 25.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 7.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.4 39.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.4 0.7 PID MYC PATHWAY C-MYC pathway
0.3 4.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.3 10.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.3 6.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 9.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 1.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 13.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 16.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 1.7 PID IL3 PATHWAY IL3-mediated signaling events
0.2 7.9 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.2 5.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 34.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 2.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.2 6.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 6.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.2 PID ARF 3PATHWAY Arf1 pathway
0.1 0.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 5.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 5.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.0 PID BMP PATHWAY BMP receptor signaling
0.1 3.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 4.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 3.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 4.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 5.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.4 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 2.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 0.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 1.3 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 4.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 8.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 1.6 ST GAQ PATHWAY G alpha q Pathway
0.1 3.4 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 2.9 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.1 PID RHOA PATHWAY RhoA signaling pathway
0.1 4.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 4.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 3.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 2.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 37.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.7 9.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.6 17.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.6 10.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.6 6.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.6 3.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5 17.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.5 13.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.4 8.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.4 11.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.4 9.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.4 12.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 10.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 6.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.3 5.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 4.7 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.3 6.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.3 9.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.3 11.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.3 5.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3 3.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 7.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 3.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 8.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 3.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 23.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.2 7.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 7.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 4.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 2.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 1.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 2.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 2.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 3.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 7.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 10.1 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.2 5.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 6.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 1.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 5.9 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 2.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 10.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 2.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 10.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 7.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 5.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 4.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 3.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 1.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 3.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 8.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 10.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 2.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 6.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 7.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 1.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.9 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.1 7.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 3.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 2.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.1 REACTOME KINESINS Genes involved in Kinesins
0.0 2.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.0 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 7.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.5 REACTOME S PHASE Genes involved in S Phase
0.0 0.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC