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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GUAGUGU

Z-value: 0.87

Motif logo

logo of

miRNA associated with seed GUAGUGU

NamemiRBASE accession
hsa-miR-142-3p.1
MIMAT0000434

Activity profile of GUAGUGU motif

Sorted Z-values of GUAGUGU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_38869410 19.03 ENST00000358869.2
FAM114A1
family with sequence similarity 114, member A1
chr2_+_187454749 18.54 ENST00000261023.3
ENST00000374907.3
ITGAV
integrin, alpha V
chr22_-_36236265 13.89 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_+_198365122 13.31 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr12_+_66217911 12.60 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr2_-_86790593 12.42 ENST00000263856.4
ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr11_+_9406169 12.07 ENST00000379719.3
ENST00000527431.1
IPO7
importin 7
chr6_+_114178512 12.01 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr6_+_13615554 11.93 ENST00000451315.2
NOL7
nucleolar protein 7, 27kDa
chr19_+_16187085 11.56 ENST00000300933.4
TPM4
tropomyosin 4
chr6_-_30712313 11.27 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr10_+_17686124 11.25 ENST00000377524.3
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr7_-_6523755 11.17 ENST00000436575.1
ENST00000258739.4
DAGLB
KDELR2
diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chrX_-_153285395 11.09 ENST00000369980.3
IRAK1
interleukin-1 receptor-associated kinase 1
chr12_-_44200052 10.91 ENST00000548315.1
ENST00000552521.1
ENST00000546662.1
ENST00000548403.1
ENST00000546506.1
TWF1
twinfilin actin-binding protein 1
chr1_-_78148324 10.35 ENST00000370801.3
ENST00000433749.1
ZZZ3
zinc finger, ZZ-type containing 3
chr2_-_161350305 10.20 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr3_+_100428268 10.04 ENST00000240851.4
TFG
TRK-fused gene
chr3_-_123603137 9.78 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK
myosin light chain kinase
chrX_+_134166333 9.53 ENST00000257013.7
FAM127A
family with sequence similarity 127, member A
chr2_+_198380289 9.37 ENST00000233892.4
ENST00000409916.1
MOB4
MOB family member 4, phocein
chr1_+_7831323 8.93 ENST00000054666.6
VAMP3
vesicle-associated membrane protein 3
chr1_+_224544552 8.54 ENST00000465271.1
ENST00000366858.3
CNIH4
cornichon family AMPA receptor auxiliary protein 4
chr10_+_63661053 8.28 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr1_+_94883931 8.12 ENST00000394233.2
ENST00000454898.2
ENST00000536817.1
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr17_-_8534067 7.63 ENST00000360416.3
ENST00000269243.4
MYH10
myosin, heavy chain 10, non-muscle
chr16_-_66785699 7.27 ENST00000258198.2
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr12_-_117628333 7.18 ENST00000427718.2
FBXO21
F-box protein 21
chrX_-_102942961 6.81 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
MORF4L2
mortality factor 4 like 2
chr6_-_134639180 6.69 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr2_-_61765315 6.66 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr17_-_48474828 6.59 ENST00000576448.1
ENST00000225972.7
LRRC59
leucine rich repeat containing 59
chr1_-_205719295 6.45 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr2_-_65357225 6.06 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A
RAB1A, member RAS oncogene family
chr1_+_93913713 6.01 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chrX_-_134186144 5.79 ENST00000370775.2
FAM127B
family with sequence similarity 127, member B
chr9_-_14314066 5.73 ENST00000397575.3
NFIB
nuclear factor I/B
chr19_-_17356697 5.71 ENST00000291442.3
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr7_+_6414128 5.54 ENST00000348035.4
ENST00000356142.4
RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
chr5_+_95066823 5.51 ENST00000506817.1
ENST00000379982.3
RHOBTB3
Rho-related BTB domain containing 3
chr2_+_9346892 5.45 ENST00000281419.3
ENST00000315273.4
ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr3_+_187930719 5.43 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr21_-_44846999 5.32 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr22_-_36784035 5.32 ENST00000216181.5
MYH9
myosin, heavy chain 9, non-muscle
chr4_-_139163491 5.07 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr20_-_45984401 4.78 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr14_-_23504087 4.75 ENST00000493471.2
ENST00000460922.2
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr5_+_42423872 4.56 ENST00000230882.4
ENST00000357703.3
GHR
growth hormone receptor
chr11_+_34642656 4.27 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr1_+_25071848 4.26 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr3_-_176914238 4.26 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr13_-_31038370 4.19 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr10_-_32345305 4.06 ENST00000302418.4
KIF5B
kinesin family member 5B
chr11_+_57520715 3.98 ENST00000524630.1
ENST00000529919.1
ENST00000399039.4
ENST00000533189.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr9_+_36190853 3.96 ENST00000433436.2
ENST00000538225.1
ENST00000540080.1
CLTA
clathrin, light chain A
chr19_+_54694119 3.81 ENST00000456872.1
ENST00000302937.4
ENST00000429671.2
TSEN34
TSEN34 tRNA splicing endonuclease subunit
chr1_+_11072696 3.70 ENST00000240185.3
ENST00000476201.1
TARDBP
TAR DNA binding protein
chr7_-_151217001 3.51 ENST00000262187.5
RHEB
Ras homolog enriched in brain
chr4_-_102268628 3.47 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr16_-_87525651 3.38 ENST00000268616.4
ZCCHC14
zinc finger, CCHC domain containing 14
chr2_-_11484710 3.37 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr7_-_105752651 3.33 ENST00000470347.1
ENST00000455385.2
SYPL1
synaptophysin-like 1
chr15_+_66161871 3.31 ENST00000569896.1
RAB11A
RAB11A, member RAS oncogene family
chr12_-_101801505 3.20 ENST00000539055.1
ENST00000551688.1
ENST00000551671.1
ENST00000261636.8
ARL1
ADP-ribosylation factor-like 1
chr5_-_142783175 3.10 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr4_-_40631859 3.06 ENST00000295971.7
ENST00000319592.4
RBM47
RNA binding motif protein 47
chr10_-_61666267 3.04 ENST00000263102.6
CCDC6
coiled-coil domain containing 6
chrX_-_41782249 3.04 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr14_+_57735614 3.02 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr6_+_34857019 2.95 ENST00000360359.3
ENST00000535627.1
ANKS1A
ankyrin repeat and sterile alpha motif domain containing 1A
chr1_-_31538517 2.94 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
PUM1
pumilio RNA-binding family member 1
chr10_+_134351319 2.88 ENST00000368594.3
ENST00000368593.3
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr11_-_796197 2.81 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr8_+_61429416 2.77 ENST00000262646.7
ENST00000531289.1
RAB2A
RAB2A, member RAS oncogene family
chr1_+_116184566 2.77 ENST00000355485.2
ENST00000369510.4
VANGL1
VANGL planar cell polarity protein 1
chr1_+_24069642 2.73 ENST00000418390.2
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr1_+_32645269 2.69 ENST00000373610.3
TXLNA
taxilin alpha
chr10_-_81205373 2.67 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr4_-_129208940 2.67 ENST00000296425.5
PGRMC2
progesterone receptor membrane component 2
chr15_+_85523671 2.59 ENST00000310298.4
ENST00000557957.1
PDE8A
phosphodiesterase 8A
chr11_+_70244510 2.53 ENST00000346329.3
ENST00000301843.8
ENST00000376561.3
CTTN
cortactin
chr11_-_65381643 2.44 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr10_+_5726764 2.41 ENST00000328090.5
ENST00000496681.1
FAM208B
family with sequence similarity 208, member B
chr3_+_128968437 2.33 ENST00000314797.6
COPG1
coatomer protein complex, subunit gamma 1
chr11_-_85780086 2.26 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr3_-_50396978 2.24 ENST00000266025.3
TMEM115
transmembrane protein 115
chr20_-_30310336 2.20 ENST00000434194.1
ENST00000376062.2
BCL2L1
BCL2-like 1
chr1_+_218519577 1.95 ENST00000366930.4
ENST00000366929.4
TGFB2
transforming growth factor, beta 2
chr7_-_41742697 1.90 ENST00000242208.4
INHBA
inhibin, beta A
chr19_-_15560730 1.73 ENST00000389282.4
ENST00000263381.7
WIZ
widely interspaced zinc finger motifs
chr1_+_87170247 1.69 ENST00000370558.4
SH3GLB1
SH3-domain GRB2-like endophilin B1
chr12_+_110719032 1.68 ENST00000395494.2
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr13_+_49550015 1.54 ENST00000492622.2
FNDC3A
fibronectin type III domain containing 3A
chr6_-_132834184 1.54 ENST00000367941.2
ENST00000367937.4
STX7
syntaxin 7
chr6_+_7107999 1.51 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr9_-_16870704 1.46 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr5_-_156486120 1.44 ENST00000522693.1
HAVCR1
hepatitis A virus cellular receptor 1
chr5_-_133512683 1.43 ENST00000353411.6
SKP1
S-phase kinase-associated protein 1
chr16_-_4166186 1.42 ENST00000294016.3
ADCY9
adenylate cyclase 9
chr8_-_28243934 1.40 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395
zinc finger protein 395
chr2_-_39664405 1.38 ENST00000341681.5
ENST00000263881.3
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chrX_+_28605516 1.28 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr17_+_44668035 1.27 ENST00000398238.4
ENST00000225282.8
NSF
N-ethylmaleimide-sensitive factor
chr18_-_23670546 1.25 ENST00000542743.1
ENST00000545952.1
ENST00000539849.1
ENST00000415083.2
SS18
synovial sarcoma translocation, chromosome 18
chr3_-_114790179 1.24 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr3_+_20081515 1.02 ENST00000263754.4
KAT2B
K(lysine) acetyltransferase 2B
chr9_-_80646374 0.97 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr2_+_204192942 0.88 ENST00000295851.5
ENST00000261017.5
ABI2
abl-interactor 2
chr6_-_36953833 0.84 ENST00000538808.1
ENST00000460219.1
ENST00000373616.5
ENST00000373627.5
MTCH1
mitochondrial carrier 1
chr5_-_114961858 0.82 ENST00000282382.4
ENST00000456936.3
ENST00000408996.4
TMED7-TICAM2
TMED7
TICAM2
TMED7-TICAM2 readthrough
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
chr6_-_136610911 0.79 ENST00000530767.1
ENST00000527759.1
ENST00000527536.1
ENST00000529826.1
ENST00000531224.1
ENST00000353331.4
BCLAF1
BCL2-associated transcription factor 1
chr14_-_21737610 0.74 ENST00000320084.7
ENST00000449098.1
ENST00000336053.6
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr6_+_53659746 0.69 ENST00000370888.1
LRRC1
leucine rich repeat containing 1
chr12_+_122242597 0.65 ENST00000267197.5
SETD1B
SET domain containing 1B
chr15_+_79165151 0.64 ENST00000331268.5
MORF4L1
mortality factor 4 like 1
chr3_+_23986748 0.60 ENST00000312521.4
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr10_-_65225722 0.53 ENST00000399251.1
JMJD1C
jumonji domain containing 1C
chrX_+_37208521 0.51 ENST00000378628.4
PRRG1
proline rich Gla (G-carboxyglutamic acid) 1
chr5_+_140625147 0.51 ENST00000231173.3
PCDHB15
protocadherin beta 15
chr11_+_120207787 0.45 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr6_+_163835669 0.39 ENST00000453779.2
ENST00000275262.7
ENST00000392127.2
ENST00000361752.3
QKI
QKI, KH domain containing, RNA binding
chr18_-_33647487 0.38 ENST00000590898.1
ENST00000357384.4
ENST00000319040.6
ENST00000588737.1
ENST00000399022.4
RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr10_+_31608054 0.35 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr16_-_74700737 0.30 ENST00000576652.1
ENST00000572337.1
ENST00000571750.1
ENST00000572990.1
ENST00000361070.4
RFWD3
ring finger and WD repeat domain 3
chr3_-_150264272 0.29 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr13_+_49280951 0.26 ENST00000282018.3
CYSLTR2
cysteinyl leukotriene receptor 2
chr21_-_39870339 0.26 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr10_-_119806085 0.26 ENST00000355624.3
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr5_+_6714718 0.25 ENST00000230859.6
ENST00000515721.1
PAPD7
PAP associated domain containing 7
chr6_-_31628512 0.20 ENST00000375911.1
C6orf47
chromosome 6 open reading frame 47
chr17_-_4806369 0.16 ENST00000293780.4
CHRNE
cholinergic receptor, nicotinic, epsilon (muscle)
chr15_-_52821247 0.08 ENST00000399231.3
ENST00000399233.2
MYO5A
myosin VA (heavy chain 12, myoxin)

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAGUGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 18.5 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
4.2 12.6 GO:2000685 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
2.5 7.6 GO:0021592 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
2.3 13.9 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
2.2 10.9 GO:0030047 actin modification(GO:0030047)
2.0 8.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
1.8 5.5 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
1.8 5.3 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
1.6 6.5 GO:0019046 release from viral latency(GO:0019046)
1.6 11.2 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
1.6 12.4 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
1.3 5.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
1.3 8.9 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
1.3 3.8 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
1.2 3.5 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
1.1 4.6 GO:0000255 allantoin metabolic process(GO:0000255)
1.1 8.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.0 4.2 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
1.0 11.2 GO:0006621 protein retention in ER lumen(GO:0006621)
1.0 1.9 GO:0051795 positive regulation of catagen(GO:0051795)
1.0 6.7 GO:0070294 renal sodium ion absorption(GO:0070294)
1.0 6.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.8 3.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.8 3.3 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.8 5.7 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.8 4.1 GO:0035617 stress granule disassembly(GO:0035617)
0.8 4.8 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.7 2.9 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.7 4.3 GO:0060613 fat pad development(GO:0060613)
0.7 10.7 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.6 1.9 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.6 12.0 GO:0051764 actin crosslink formation(GO:0051764)
0.6 1.7 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.6 1.7 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.5 3.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.4 2.9 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.4 7.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.4 3.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.4 1.5 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.4 3.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.4 4.3 GO:0001886 endothelial cell morphogenesis(GO:0001886) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.3 2.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.3 1.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3 6.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.3 5.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.3 2.3 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.3 2.5 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.3 2.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.3 3.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.3 7.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 5.7 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.2 1.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.2 4.0 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.2 2.9 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.2 3.0 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 7.3 GO:0051642 centrosome localization(GO:0051642)
0.2 1.7 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 8.3 GO:0060612 adipose tissue development(GO:0060612)
0.2 1.5 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.2 3.5 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 1.4 GO:0010265 SCF complex assembly(GO:0010265)
0.1 11.6 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 0.8 GO:0071651 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 2.3 GO:0051683 establishment of Golgi localization(GO:0051683)
0.1 4.0 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 11.3 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 1.5 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 2.6 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.1 0.3 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 1.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 12.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 1.4 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 1.5 GO:0043586 tongue development(GO:0043586)
0.1 7.1 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.1 11.8 GO:2001020 regulation of response to DNA damage stimulus(GO:2001020)
0.1 0.8 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.1 0.3 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.1 3.0 GO:0016197 endosomal transport(GO:0016197)
0.1 3.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 13.3 GO:0006457 protein folding(GO:0006457)
0.0 0.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.7 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.6 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 1.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 4.5 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.0 1.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 1.4 GO:0030260 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 18.5 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
3.7 11.1 GO:0033565 ESCRT-0 complex(GO:0033565)
2.6 13.0 GO:0097513 myosin II filament(GO:0097513)
2.2 11.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
1.5 4.6 GO:0070195 growth hormone receptor complex(GO:0070195)
1.1 12.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.0 12.4 GO:0000815 ESCRT III complex(GO:0000815)
1.0 3.8 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.8 12.0 GO:0043073 germ cell nucleus(GO:0043073)
0.7 3.7 GO:0005726 perichromatin fibrils(GO:0005726) interchromatin granule(GO:0035061)
0.7 3.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.6 1.9 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.6 11.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.6 11.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.6 6.7 GO:0005642 annulate lamellae(GO:0005642)
0.5 5.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.4 4.0 GO:0071439 clathrin complex(GO:0071439)
0.4 2.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.4 10.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.3 4.0 GO:0005915 zonula adherens(GO:0005915)
0.3 3.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.3 4.1 GO:0035253 ciliary rootlet(GO:0035253)
0.3 4.7 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.2 7.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 7.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 3.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 11.2 GO:0005801 cis-Golgi network(GO:0005801)
0.2 2.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 3.0 GO:0005652 nuclear lamina(GO:0005652)
0.2 1.7 GO:0097470 ribbon synapse(GO:0097470)
0.2 2.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 15.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 9.6 GO:0031201 SNARE complex(GO:0031201)
0.2 1.4 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 8.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 9.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 15.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.0 GO:0005955 calcineurin complex(GO:0005955)
0.1 11.5 GO:0005643 nuclear pore(GO:0005643)
0.1 5.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 11.9 GO:0030175 filopodium(GO:0030175)
0.1 3.9 GO:0043198 dendritic shaft(GO:0043198)
0.1 2.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 4.3 GO:0005902 microvillus(GO:0005902)
0.1 11.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.7 GO:0000421 autophagosome membrane(GO:0000421)
0.1 5.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 3.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 3.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.3 GO:0071564 npBAF complex(GO:0071564)
0.0 2.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.6 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 2.9 GO:0043005 neuron projection(GO:0043005)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 3.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.7 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.3 GO:0031514 motile cilium(GO:0031514)
0.0 14.7 GO:0005794 Golgi apparatus(GO:0005794)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.6 GO:0035501 MH1 domain binding(GO:0035501)
2.8 11.2 GO:0005046 KDEL sequence binding(GO:0005046)
2.5 12.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
2.0 9.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.6 11.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
1.3 3.8 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
1.2 8.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.0 4.1 GO:0099609 microtubule lateral binding(GO:0099609)
1.0 5.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.9 5.5 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.9 8.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.7 4.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.7 12.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.6 1.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.6 1.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.6 3.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.6 2.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.6 6.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.6 1.7 GO:0070984 SET domain binding(GO:0070984)
0.6 13.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.5 6.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 5.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.4 7.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.4 5.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 3.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 10.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 2.9 GO:0042731 inositol-polyphosphate 5-phosphatase activity(GO:0004445) PH domain binding(GO:0042731)
0.3 12.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.3 2.8 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 3.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 1.0 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 2.2 GO:0051434 BH3 domain binding(GO:0051434)
0.2 11.6 GO:0005080 protein kinase C binding(GO:0005080)
0.2 7.6 GO:0003785 actin monomer binding(GO:0003785)
0.2 5.4 GO:0070064 proline-rich region binding(GO:0070064)
0.2 4.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 1.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 4.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 2.5 GO:0005522 profilin binding(GO:0005522)
0.1 11.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 11.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 4.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 5.6 GO:0019905 syntaxin binding(GO:0019905)
0.1 3.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 1.7 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 6.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 12.9 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 19.9 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 4.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 3.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.5 GO:0019003 GDP binding(GO:0019003)
0.0 2.7 GO:0005496 steroid binding(GO:0005496)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 1.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 9.1 GO:0019900 kinase binding(GO:0019900)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 24.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.5 14.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.4 6.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.4 21.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 4.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 12.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 4.0 PID ARF 3PATHWAY Arf1 pathway
0.2 3.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 8.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 6.7 PID INSULIN PATHWAY Insulin Pathway
0.1 11.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 2.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 5.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 6.1 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.4 PID IFNG PATHWAY IFN-gamma pathway
0.1 4.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 1.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 5.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 3.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.5 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 1.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 PID TNF PATHWAY TNF receptor signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 11.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.0 11.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
1.0 18.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.9 23.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.5 22.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4 8.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.4 21.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 11.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 6.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 4.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 4.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 5.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 3.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 4.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 4.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 5.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 2.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 5.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 6.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 7.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 4.4 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1 3.6 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+