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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HIC1

Z-value: 2.23

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Transcription factors associated with HIC1

Gene Symbol Gene ID Gene Info
ENSG00000177374.8 HIC ZBTB transcriptional repressor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIC1hg19_v2_chr17_+_1959369_1959604,
hg19_v2_chr17_+_1958388_1958404
0.401.0e-09Click!

Activity profile of HIC1 motif

Sorted Z-values of HIC1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_6845384 77.19 ENST00000303635.7
calmodulin binding transcription activator 1
chr15_+_68871308 47.32 ENST00000261861.5
coronin, actin binding protein, 2B
chr16_+_58497567 43.51 ENST00000258187.5
NDRG family member 4
chr19_+_709101 43.51 ENST00000338448.5
paralemmin
chr19_+_708910 42.23 ENST00000264560.7
paralemmin
chr16_+_1662326 41.01 ENST00000397412.3
Crm, cramped-like (Drosophila)
chr18_-_74844727 40.67 ENST00000355994.2
ENST00000579129.1
myelin basic protein
chr9_-_101471479 40.29 ENST00000259455.2
gamma-aminobutyric acid (GABA) B receptor, 2
chr9_+_137979506 39.96 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
olfactomedin 1
chr20_+_44034804 39.96 ENST00000357275.2
ENST00000372720.3
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr4_-_109684120 39.96 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ethanolamine-phosphate phospho-lyase
chr19_+_35521572 36.67 ENST00000262631.5
sodium channel, voltage-gated, type I, beta subunit
chr2_-_224903995 36.07 ENST00000409304.1
ENST00000454956.1
ENST00000258405.4
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr16_+_226658 35.77 ENST00000320868.5
ENST00000397797.1
hemoglobin, alpha 1
chr19_+_35521616 35.23 ENST00000595652.1
sodium channel, voltage-gated, type I, beta subunit
chrX_+_38420783 34.83 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
tetraspanin 7
chr6_-_84419101 34.37 ENST00000520302.1
ENST00000520213.1
ENST00000439399.2
ENST00000428679.2
ENST00000437520.1
synaptosomal-associated protein, 91kDa
chr12_-_45270151 32.53 ENST00000429094.2
NEL-like 2 (chicken)
chr7_-_44365020 32.37 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
calcium/calmodulin-dependent protein kinase II beta
chr17_-_15903002 31.94 ENST00000399277.1
zinc finger, SWIM-type containing 7
chr6_-_84418841 31.90 ENST00000369694.2
ENST00000195649.6
synaptosomal-associated protein, 91kDa
chr11_-_2160611 31.86 ENST00000416167.2
insulin-like growth factor 2 (somatomedin A)
chr12_-_45270077 31.75 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chrX_+_38420623 31.70 ENST00000378482.2
tetraspanin 7
chr18_+_77439775 31.31 ENST00000299543.7
ENST00000075430.7
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr10_+_121485588 31.04 ENST00000361976.2
ENST00000369083.3
inositol polyphosphate-5-phosphatase F
chr12_+_121078355 29.84 ENST00000316803.3
calcium binding protein 1
chr10_+_124221036 29.56 ENST00000368984.3
HtrA serine peptidase 1
chr11_-_12030905 28.85 ENST00000326932.4
dickkopf WNT signaling pathway inhibitor 3
chr16_-_1661988 28.76 ENST00000426508.2
intraflagellar transport 140 homolog (Chlamydomonas)
chr20_+_44034676 28.62 ENST00000372723.3
ENST00000372722.3
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr8_-_120685608 28.50 ENST00000427067.2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr5_+_134240588 28.14 ENST00000254908.6
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr6_-_46459099 27.97 ENST00000371374.1
regulator of calcineurin 2
chr13_+_42031679 27.78 ENST00000379359.3
regulator of cell cycle
chr9_+_130374537 27.64 ENST00000373302.3
ENST00000373299.1
syntaxin binding protein 1
chr15_+_80696666 27.13 ENST00000303329.4
aryl-hydrocarbon receptor nuclear translocator 2
chr11_+_70244510 25.13 ENST00000346329.3
ENST00000301843.8
ENST00000376561.3
cortactin
chr11_-_777467 24.81 ENST00000397472.2
ENST00000524550.1
ENST00000319863.8
ENST00000526325.1
ENST00000442059.2
Parkinson disease 7 domain containing 1
chr15_+_68871569 24.61 ENST00000566799.1
coronin, actin binding protein, 2B
chr2_+_241938255 24.46 ENST00000401884.1
ENST00000405547.3
ENST00000310397.8
ENST00000342631.6
sushi, nidogen and EGF-like domains 1
chr2_-_99552620 23.85 ENST00000428096.1
ENST00000397899.2
ENST00000420294.1
KIAA1211-like
chr8_+_104152922 23.67 ENST00000309982.5
ENST00000438105.2
ENST00000297574.6
brain and acute leukemia, cytoplasmic
chr14_+_102027688 23.43 ENST00000510508.4
ENST00000359323.3
deiodinase, iodothyronine, type III
chr7_+_45613958 23.32 ENST00000297323.7
adenylate cyclase 1 (brain)
chr6_-_109330702 22.97 ENST00000356644.7
sestrin 1
chr2_-_38604398 22.43 ENST00000443098.1
ENST00000449130.1
ENST00000378954.4
ENST00000539122.1
ENST00000419554.2
ENST00000451483.1
ENST00000406122.1
atlastin GTPase 2
chr17_-_15165854 22.31 ENST00000395936.1
ENST00000395938.2
peripheral myelin protein 22
chr1_+_169075554 22.24 ENST00000367815.4
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr20_+_44035200 22.06 ENST00000372717.1
ENST00000360981.4
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr6_+_107811162 22.05 ENST00000317357.5
sine oculis binding protein homolog (Drosophila)
chr1_+_10270863 22.04 ENST00000377093.4
ENST00000263934.6
kinesin family member 1B
chr12_+_53440753 21.82 ENST00000379902.3
tensin like C1 domain containing phosphatase (tensin 2)
chr4_-_57522598 21.36 ENST00000553379.2
HOP homeobox
chr3_+_53528659 21.30 ENST00000350061.5
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr8_-_101571964 21.22 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ankyrin repeat domain 46
chr6_+_43543864 21.19 ENST00000372236.4
ENST00000535400.1
polymerase (DNA directed), eta
chr4_-_57522673 21.06 ENST00000381255.3
ENST00000317745.7
ENST00000555760.2
ENST00000556614.2
HOP homeobox
chr22_+_33197683 21.04 ENST00000266085.6
TIMP metallopeptidase inhibitor 3
chr17_+_30813576 20.93 ENST00000313401.3
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr20_-_50384864 20.80 ENST00000311637.5
ENST00000402822.1
ATPase, class II, type 9A
chr20_-_50385138 20.74 ENST00000338821.5
ATPase, class II, type 9A
chr8_-_101571933 20.56 ENST00000520311.1
ankyrin repeat domain 46
chrX_-_2418596 20.55 ENST00000381218.3
zinc finger, BED-type containing 1
chr1_-_241520525 20.47 ENST00000366565.1
regulator of G-protein signaling 7
chr7_+_4721885 20.46 ENST00000328914.4
forkhead box K1
chr9_+_17579084 20.29 ENST00000380607.4
SH3-domain GRB2-like 2
chr2_+_46524537 20.21 ENST00000263734.3
endothelial PAS domain protein 1
chr6_-_56819385 20.19 ENST00000370754.5
ENST00000449297.2
dystonin
chr10_-_81205373 20.09 ENST00000372336.3
zinc finger, CCHC domain containing 24
chr9_+_137967366 20.05 ENST00000252854.4
olfactomedin 1
chr17_-_74236382 20.02 ENST00000592271.1
ENST00000319945.6
ENST00000269391.6
ring finger protein 157
chr22_-_21213029 19.96 ENST00000572273.1
ENST00000255882.6
phosphatidylinositol 4-kinase, catalytic, alpha
chr11_-_66336060 19.81 ENST00000310325.5
cathepsin F
chr16_+_84002234 19.81 ENST00000305202.4
N-terminal EF-hand calcium binding protein 2
chr2_-_175870085 19.78 ENST00000409156.3
chimerin 1
chr10_+_126150369 19.66 ENST00000392757.4
ENST00000368842.5
ENST00000368839.1
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr19_-_460996 19.62 ENST00000264554.6
SHC (Src homology 2 domain containing) transforming protein 2
chr17_-_79139817 19.34 ENST00000326724.4
apoptosis-associated tyrosine kinase
chr4_-_57522470 19.33 ENST00000503639.3
HOP homeobox
chr19_-_19006890 19.32 ENST00000247005.6
growth differentiation factor 1
chr8_+_1922024 19.22 ENST00000320248.3
kelch repeat and BTB (POZ) domain containing 11
chr19_-_42746714 19.16 ENST00000222330.3
glycogen synthase kinase 3 alpha
chr22_-_45559642 19.05 ENST00000426282.2
CTA-217C2.1
chr2_+_20646824 18.86 ENST00000272233.4
ras homolog family member B
chr6_-_84418860 18.84 ENST00000521743.1
synaptosomal-associated protein, 91kDa
chr16_+_66914264 18.81 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr19_-_49944806 18.74 ENST00000221485.3
solute carrier family 17 (vesicular glutamate transporter), member 7
chr17_+_38083977 18.60 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
chr7_-_99756293 18.54 ENST00000316937.3
ENST00000456769.1
chromosome 7 open reading frame 43
chr3_+_32147997 18.48 ENST00000282541.5
glycerol-3-phosphate dehydrogenase 1-like
chr4_+_3768075 18.45 ENST00000509482.1
ENST00000330055.5
adrenoceptor alpha 2C
chr17_-_80656528 18.37 ENST00000538809.2
ENST00000269347.6
ENST00000571995.1
RAB40B, member RAS oncogene family
chr2_-_175869936 18.35 ENST00000409900.3
chimerin 1
chr4_+_1795012 18.18 ENST00000481110.2
ENST00000340107.4
ENST00000440486.2
ENST00000412135.2
fibroblast growth factor receptor 3
chr19_+_18718214 17.77 ENST00000600490.1
transmembrane protein 59-like
chr3_+_49027308 17.76 ENST00000383729.4
ENST00000343546.4
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr5_+_76506706 17.60 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
phosphodiesterase 8B
chrX_+_110187513 17.56 ENST00000446737.1
ENST00000425146.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr12_-_124457371 17.49 ENST00000238156.3
ENST00000545037.1
coiled-coil domain containing 92
chr21_-_34100244 17.47 ENST00000382491.3
ENST00000357345.3
ENST00000429236.1
synaptojanin 1
chr9_-_139922631 17.46 ENST00000341511.6
ATP-binding cassette, sub-family A (ABC1), member 2
chr4_+_2965307 17.41 ENST00000398051.4
ENST00000503518.2
ENST00000398052.4
ENST00000345167.6
ENST00000504933.1
ENST00000442472.2
G protein-coupled receptor kinase 4
chr7_-_22396533 17.38 ENST00000344041.6
Rap guanine nucleotide exchange factor (GEF) 5
chr3_-_149688502 17.17 ENST00000481767.1
ENST00000475518.1
profilin 2
chr1_-_6240183 17.14 ENST00000262450.3
ENST00000378021.1
chromodomain helicase DNA binding protein 5
chr7_-_124405681 17.13 ENST00000303921.2
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr22_-_39239987 17.05 ENST00000333039.2
neuronal pentraxin receptor
chr6_+_147830063 16.93 ENST00000367474.1
sterile alpha motif domain containing 5
chr12_-_53574376 16.90 ENST00000267085.4
ENST00000379850.3
ENST00000379846.1
ENST00000424990.1
cysteine sulfinic acid decarboxylase
chr11_-_108369101 16.90 ENST00000323468.5
KDEL (Lys-Asp-Glu-Leu) containing 2
chr14_+_65171099 16.87 ENST00000247226.7
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr6_+_43543942 16.87 ENST00000372226.1
ENST00000443535.1
polymerase (DNA directed), eta
chr15_-_71146480 16.87 ENST00000299213.8
La ribonucleoprotein domain family, member 6
chr2_+_220379052 16.78 ENST00000347842.3
ENST00000358078.4
acid-sensing (proton-gated) ion channel family member 4
chr6_+_31865552 16.68 ENST00000469372.1
ENST00000497706.1
complement component 2
chr2_-_86564776 16.66 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
receptor accessory protein 1
chr1_+_184356188 16.63 ENST00000235307.6
chromosome 1 open reading frame 21
chr14_+_73704201 16.60 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
papilin, proteoglycan-like sulfated glycoprotein
chr9_+_124030338 16.53 ENST00000449773.1
ENST00000432226.1
ENST00000436847.1
ENST00000394353.2
ENST00000449733.1
ENST00000412819.1
ENST00000341272.2
ENST00000373808.2
gelsolin
chr8_+_136469684 16.52 ENST00000355849.5
KH domain containing, RNA binding, signal transduction associated 3
chr16_+_3096638 16.44 ENST00000336577.4
matrix metallopeptidase 25
chr1_+_24882560 16.31 ENST00000374392.2
noncompact myelin associated protein
chr20_-_48532019 16.13 ENST00000289431.5
spermatogenesis associated 2
chr14_+_96505659 16.11 ENST00000555004.1
chromosome 14 open reading frame 132
chr3_-_149688655 16.08 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
profilin 2
chr5_-_146889619 16.05 ENST00000343218.5
dihydropyrimidinase-like 3
chr12_-_53574418 16.01 ENST00000379843.3
ENST00000453446.2
ENST00000437073.1
cysteine sulfinic acid decarboxylase
chr18_-_72265035 15.94 ENST00000585279.1
ENST00000580048.1
long intergenic non-protein coding RNA 909
chr8_-_110703819 15.93 ENST00000532779.1
ENST00000534578.1
syntabulin (syntaxin-interacting)
chr19_-_18717627 15.74 ENST00000392386.3
cytokine receptor-like factor 1
chr1_+_9599540 15.74 ENST00000302692.6
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr4_-_5890145 15.48 ENST00000397890.2
collapsin response mediator protein 1
chr11_-_62389449 15.47 ENST00000534026.1
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr9_-_91793675 15.41 ENST00000375835.4
ENST00000375830.1
SHC (Src homology 2 domain containing) transforming protein 3
chr21_-_38338773 15.40 ENST00000399120.1
ENST00000419461.1
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr9_-_139922726 15.31 ENST00000265662.5
ENST00000371605.3
ATP-binding cassette, sub-family A (ABC1), member 2
chr20_+_23016057 15.20 ENST00000255008.3
somatostatin receptor 4
chr4_+_4388805 15.16 ENST00000504171.1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr4_-_5894777 15.07 ENST00000324989.7
collapsin response mediator protein 1
chr19_+_33685490 15.07 ENST00000253193.7
low density lipoprotein receptor-related protein 3
chr13_+_27131887 14.92 ENST00000335327.5
WAS protein family, member 3
chr1_+_3569072 14.87 ENST00000378295.4
ENST00000604074.1
tumor protein p73
chr1_-_11865982 14.86 ENST00000418034.1
methylenetetrahydrofolate reductase (NAD(P)H)
chr21_-_34100341 14.78 ENST00000382499.2
ENST00000433931.2
synaptojanin 1
chr15_-_72410350 14.71 ENST00000356056.5
ENST00000424560.1
ENST00000444904.1
myosin IXA
chr9_-_140353748 14.57 ENST00000371472.2
ENST00000371475.3
ENST00000265663.7
ENST00000437259.1
ENST00000392812.4
ENST00000371474.3
ENST00000371473.3
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr15_+_29131103 14.49 ENST00000558402.1
ENST00000558330.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr19_+_16999654 14.49 ENST00000248076.3
coagulation factor II (thrombin) receptor-like 3
chr19_-_19006920 14.44 ENST00000429504.2
ENST00000427170.2
ceramide synthase 1
chr16_+_85061367 14.41 ENST00000538274.1
ENST00000258180.3
KIAA0513
chr6_+_19837592 14.28 ENST00000378700.3
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr12_+_12878829 14.24 ENST00000326765.6
apolipoprotein L domain containing 1
chr19_-_2236290 14.21 ENST00000591099.2
ENST00000586608.2
ENST00000326631.2
ENST00000587962.2
pleckstrin homology domain containing, family J member 1
chr1_+_3569129 14.14 ENST00000354437.4
ENST00000357733.3
ENST00000346387.4
tumor protein p73
chr19_+_10541462 14.13 ENST00000293683.5
phosphodiesterase 4A, cAMP-specific
chr8_+_124194752 14.06 ENST00000318462.6
family with sequence similarity 83, member A
chr3_-_52001448 14.05 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
poly(rC) binding protein 4
chrX_-_153363188 14.05 ENST00000303391.6
methyl CpG binding protein 2 (Rett syndrome)
chr9_-_136857403 14.03 ENST00000406606.3
ENST00000371850.3
vav 2 guanine nucleotide exchange factor
chr8_+_26435359 14.02 ENST00000311151.5
dihydropyrimidinase-like 2
chr1_-_21948906 13.94 ENST00000374761.2
ENST00000599760.1
RAP1 GTPase activating protein
chr16_+_1756162 13.90 ENST00000250894.4
ENST00000356010.5
mitogen-activated protein kinase 8 interacting protein 3
chr1_-_54872059 13.85 ENST00000371320.3
single stranded DNA binding protein 3
chr17_-_10101868 13.74 ENST00000432992.2
ENST00000540214.1
growth arrest-specific 7
chrX_-_8700171 13.72 ENST00000262648.3
Kallmann syndrome 1 sequence
chr5_+_149109825 13.71 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr7_+_98246588 13.71 ENST00000265634.3
neuronal pentraxin II
chr1_-_21995794 13.70 ENST00000542643.2
ENST00000374765.4
ENST00000317967.7
RAP1 GTPase activating protein
chr17_+_18163848 13.68 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
mitochondrial elongation factor 2
chr12_+_113376249 13.62 ENST00000551007.1
ENST00000548514.1
2'-5'-oligoadenylate synthetase 3, 100kDa
chr9_-_13279563 13.58 ENST00000541718.1
multiple PDZ domain protein
chr1_+_156611704 13.56 ENST00000329117.5
brevican
chr12_+_119616447 13.54 ENST00000281938.2
heat shock 22kDa protein 8
chr16_-_75498308 13.52 ENST00000569540.1
transmembrane protein 170A
chr2_-_183903133 13.49 ENST00000361354.4
NCK-associated protein 1
chr7_-_122526799 13.33 ENST00000334010.7
ENST00000313070.7
Ca++-dependent secretion activator 2
chr14_+_33408449 13.30 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
neuronal PAS domain protein 3
chr11_+_121322832 13.29 ENST00000260197.7
sortilin-related receptor, L(DLR class) A repeats containing
chr20_-_35492048 13.27 ENST00000237536.4
suppressor of glucose, autophagy associated 1
chr3_-_127541679 13.25 ENST00000265052.5
monoglyceride lipase
chr3_+_14989186 13.19 ENST00000435454.1
ENST00000323373.6
nuclear receptor subfamily 2, group C, member 2
chr7_+_2559399 13.17 ENST00000222725.5
ENST00000359574.3
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_-_85930823 13.16 ENST00000284031.8
ENST00000539042.1
dimethylarginine dimethylaminohydrolase 1
chr20_+_4667094 13.16 ENST00000424424.1
ENST00000457586.1
prion protein
chr9_+_129089088 13.15 ENST00000361171.3
ENST00000545391.1
multivesicular body subunit 12B
chr7_-_73133959 13.07 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
syntaxin 1A (brain)
chr8_+_104513086 13.06 ENST00000406091.3
regulating synaptic membrane exocytosis 2
chr3_-_149688896 13.04 ENST00000239940.7
profilin 2
chr8_-_33424636 13.03 ENST00000256257.1
ring finger protein 122
chr12_-_53574671 13.01 ENST00000444623.1
cysteine sulfinic acid decarboxylase
chr14_-_101034407 12.92 ENST00000443071.2
ENST00000557378.1
brain-enriched guanylate kinase-associated
chr17_-_4167142 12.88 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ankyrin repeat and FYVE domain containing 1
chr19_-_49140609 12.87 ENST00000601104.1
D site of albumin promoter (albumin D-box) binding protein
chr10_-_120514720 12.87 ENST00000369151.3
ENST00000340214.4
CDK2-associated, cullin domain 1
chr21_+_47878757 12.78 ENST00000400274.1
ENST00000427143.2
ENST00000318711.7
ENST00000457905.3
ENST00000466639.1
ENST00000435722.3
ENST00000417564.2
DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr9_-_130742792 12.77 ENST00000373095.1
family with sequence similarity 102, member A
chr1_-_241520385 12.76 ENST00000366564.1
regulator of G-protein signaling 7
chr12_-_112819896 12.73 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
HECT domain containing E3 ubiquitin protein ligase 4
chr12_+_125478241 12.67 ENST00000341446.8
BRI3 binding protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HIC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
24.0 71.9 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
11.5 45.9 GO:0042412 taurine biosynthetic process(GO:0042412)
11.0 88.3 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
10.4 31.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
10.2 30.5 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
10.1 50.4 GO:0061107 seminal vesicle development(GO:0061107)
9.4 18.7 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
9.3 27.8 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
9.2 27.7 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
9.2 27.6 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
9.2 27.6 GO:0007412 axon target recognition(GO:0007412) regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
9.0 36.0 GO:1904978 regulation of endosome organization(GO:1904978)
8.7 78.7 GO:0003190 atrioventricular valve formation(GO:0003190)
7.4 22.2 GO:0014807 regulation of somitogenesis(GO:0014807)
7.3 22.0 GO:1904647 response to rotenone(GO:1904647)
7.2 28.8 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
7.2 21.5 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
7.2 14.4 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134)
7.0 34.9 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
6.8 87.8 GO:2001135 regulation of endocytic recycling(GO:2001135)
6.6 19.8 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
6.6 32.8 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
6.5 91.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
6.4 19.2 GO:0006258 UDP-glucose catabolic process(GO:0006258)
6.1 12.2 GO:1990523 bone regeneration(GO:1990523)
6.0 18.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
5.9 29.6 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
5.6 22.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
5.5 22.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
5.4 38.1 GO:0071494 cellular response to UV-C(GO:0071494)
5.4 16.3 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
5.4 16.3 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
5.3 21.0 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
5.2 15.7 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
5.1 15.4 GO:0070781 response to biotin(GO:0070781)
4.9 19.6 GO:0060594 mammary gland specification(GO:0060594)
4.7 56.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
4.6 60.4 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
4.6 18.5 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072) negative regulation of protein kinase C signaling(GO:0090038)
4.6 18.4 GO:0032811 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
4.5 4.5 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
4.4 39.5 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
4.2 46.1 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
4.2 12.5 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
4.2 12.5 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
4.1 20.6 GO:1990504 dense core granule exocytosis(GO:1990504)
4.1 8.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
4.1 12.2 GO:0003383 apical constriction(GO:0003383) mesoderm migration involved in gastrulation(GO:0007509)
4.1 20.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
4.1 12.2 GO:1990502 dense core granule maturation(GO:1990502)
3.9 7.7 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
3.8 11.5 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
3.7 22.4 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
3.7 29.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
3.7 106.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
3.7 25.6 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
3.6 14.4 GO:0071492 cellular response to UV-A(GO:0071492)
3.5 17.5 GO:0097338 response to clozapine(GO:0097338)
3.5 27.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
3.3 23.4 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
3.3 10.0 GO:0048511 rhythmic process(GO:0048511)
3.3 9.9 GO:0071529 cementum mineralization(GO:0071529)
3.3 16.5 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
3.3 13.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
3.2 9.7 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
3.2 28.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
3.2 28.4 GO:0008090 retrograde axonal transport(GO:0008090)
3.1 12.5 GO:0003219 cardiac right ventricle formation(GO:0003219)
3.1 9.4 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
3.1 6.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
3.1 15.3 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
3.1 12.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
3.0 15.2 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
3.0 14.9 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
2.9 11.7 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
2.9 20.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
2.9 5.8 GO:0021586 pons maturation(GO:0021586)
2.9 11.4 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
2.9 11.4 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
2.8 8.5 GO:1900369 transcription, RNA-templated(GO:0001172) regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369) positive regulation of protein localization to nucleolus(GO:1904751)
2.8 11.3 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
2.8 11.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
2.7 8.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
2.7 10.9 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
2.7 8.1 GO:0060437 lung growth(GO:0060437)
2.7 8.0 GO:0031052 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
2.7 5.3 GO:1990164 histone H2A phosphorylation(GO:1990164)
2.7 13.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
2.6 13.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
2.6 18.2 GO:0060992 response to fungicide(GO:0060992)
2.6 23.0 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
2.5 20.2 GO:0043129 surfactant homeostasis(GO:0043129)
2.5 12.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
2.5 22.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
2.5 12.3 GO:1904139 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
2.5 7.4 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
2.4 4.9 GO:0070256 negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
2.4 2.4 GO:0007497 posterior midgut development(GO:0007497)
2.4 35.8 GO:0015671 oxygen transport(GO:0015671)
2.4 7.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
2.4 9.4 GO:0006114 glycerol biosynthetic process(GO:0006114)
2.3 11.4 GO:0071321 cellular response to cGMP(GO:0071321)
2.3 27.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
2.3 9.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
2.2 6.6 GO:0071373 luteinizing hormone signaling pathway(GO:0042700) cellular response to luteinizing hormone stimulus(GO:0071373)
2.2 24.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
2.2 13.2 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
2.2 6.5 GO:0046952 ketone body catabolic process(GO:0046952)
2.2 10.9 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
2.1 12.9 GO:0048549 positive regulation of pinocytosis(GO:0048549)
2.1 8.5 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
2.1 6.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
2.1 10.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
2.0 10.1 GO:0030035 microspike assembly(GO:0030035)
2.0 44.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
2.0 30.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
2.0 8.0 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
2.0 5.9 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
2.0 17.8 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
2.0 41.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
1.9 5.8 GO:0006566 threonine metabolic process(GO:0006566)
1.9 11.7 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
1.9 5.8 GO:0072177 mesonephric duct development(GO:0072177)
1.9 9.7 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
1.9 9.6 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.9 9.5 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
1.9 5.7 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
1.9 13.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.9 35.8 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
1.9 20.6 GO:0060022 hard palate development(GO:0060022)
1.9 7.5 GO:0001826 inner cell mass cell differentiation(GO:0001826)
1.9 13.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
1.9 5.6 GO:0010265 SCF complex assembly(GO:0010265)
1.8 12.9 GO:0007256 activation of JNKK activity(GO:0007256)
1.8 9.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
1.8 14.5 GO:0060155 platelet dense granule organization(GO:0060155)
1.8 5.4 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
1.8 19.9 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
1.8 10.7 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
1.8 5.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
1.8 5.3 GO:0100009 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
1.8 22.9 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
1.7 45.1 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
1.7 5.2 GO:2000173 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
1.7 6.9 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.7 13.7 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
1.7 5.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
1.7 17.1 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
1.7 29.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
1.7 5.0 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
1.7 6.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
1.7 16.6 GO:0042118 endothelial cell activation(GO:0042118)
1.7 52.8 GO:0008045 motor neuron axon guidance(GO:0008045)
1.6 9.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
1.6 8.2 GO:0090650 rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
1.6 4.9 GO:0043615 astrocyte cell migration(GO:0043615)
1.6 19.5 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
1.6 8.0 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
1.6 4.8 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.6 9.5 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.5 6.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
1.5 12.4 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
1.5 47.4 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
1.5 4.6 GO:0097359 UDP-glucosylation(GO:0097359)
1.5 4.6 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
1.5 9.1 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
1.5 16.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.5 7.6 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
1.5 6.0 GO:0032074 negative regulation of nuclease activity(GO:0032074)
1.5 14.9 GO:0070830 bicellular tight junction assembly(GO:0070830)
1.5 11.9 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.5 14.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
1.4 1.4 GO:0003343 proepicardium development(GO:0003342) septum transversum development(GO:0003343)
1.4 8.6 GO:0021819 layer formation in cerebral cortex(GO:0021819)
1.4 50.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
1.4 2.9 GO:0070307 lens fiber cell development(GO:0070307)
1.4 8.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
1.4 8.5 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
1.4 6.9 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
1.4 9.7 GO:0051639 actin filament network formation(GO:0051639)
1.4 13.7 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
1.4 6.8 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
1.3 9.4 GO:0043634 polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634)
1.3 9.4 GO:0042126 nitrate metabolic process(GO:0042126)
1.3 10.7 GO:0061314 Notch signaling involved in heart development(GO:0061314)
1.3 17.4 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
1.3 6.7 GO:0034334 adherens junction maintenance(GO:0034334)
1.3 8.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.3 4.0 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
1.3 7.8 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
1.3 7.8 GO:0098722 asymmetric neuroblast division(GO:0055059) asymmetric stem cell division(GO:0098722)
1.3 23.3 GO:0032060 bleb assembly(GO:0032060)
1.3 6.4 GO:1990034 calcium ion export from cell(GO:1990034)
1.3 6.4 GO:0000189 MAPK import into nucleus(GO:0000189)
1.3 19.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.3 3.8 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
1.3 46.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
1.3 12.5 GO:0030322 stabilization of membrane potential(GO:0030322)
1.3 6.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125) minus-end-directed organelle transport along microtubule(GO:0072385)
1.2 7.4 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
1.2 3.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
1.2 7.1 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929)
1.2 3.5 GO:0036071 N-glycan fucosylation(GO:0036071)
1.2 3.5 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
1.2 10.6 GO:1903140 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
1.2 8.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
1.1 3.4 GO:0043068 positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
1.1 17.0 GO:0071318 cellular response to ATP(GO:0071318)
1.1 6.5 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
1.1 8.7 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
1.1 11.9 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
1.1 3.2 GO:1902490 regulation of sperm capacitation(GO:1902490)
1.1 2.1 GO:0003348 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
1.1 2.1 GO:0031133 regulation of axon diameter(GO:0031133)
1.1 6.4 GO:0060013 righting reflex(GO:0060013)
1.1 10.6 GO:0060700 regulation of ribonuclease activity(GO:0060700)
1.1 2.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
1.1 10.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
1.0 19.8 GO:0035988 chondrocyte proliferation(GO:0035988)
1.0 5.2 GO:0009636 response to toxic substance(GO:0009636)
1.0 7.2 GO:0016322 neuron remodeling(GO:0016322)
1.0 59.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
1.0 6.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
1.0 2.0 GO:0098868 endochondral bone growth(GO:0003416) bone growth(GO:0098868)
1.0 9.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
1.0 5.0 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
1.0 8.9 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
1.0 3.9 GO:0016198 axon choice point recognition(GO:0016198)
1.0 4.9 GO:0061511 centriole elongation(GO:0061511)
1.0 13.7 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
1.0 24.4 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
1.0 6.8 GO:0035897 proteolysis in other organism(GO:0035897)
1.0 23.2 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
1.0 1.0 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
1.0 11.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
1.0 6.7 GO:0046618 drug export(GO:0046618)
1.0 5.7 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
1.0 11.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
1.0 3.8 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
1.0 10.5 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.9 32.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.9 7.4 GO:0046325 negative regulation of glucose import(GO:0046325)
0.9 21.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.9 3.7 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086) positive regulation of transcription by glucose(GO:0046016)
0.9 9.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.9 0.9 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.9 16.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.9 11.7 GO:0008089 anterograde axonal transport(GO:0008089)
0.9 7.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.9 7.2 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.9 5.3 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.9 16.0 GO:0051764 actin crosslink formation(GO:0051764)
0.9 8.9 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.9 9.7 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.9 2.6 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.8 6.8 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.8 8.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.8 8.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.8 1.7 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.8 7.5 GO:0006338 chromatin remodeling(GO:0006338)
0.8 5.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.8 2.5 GO:0033184 positive regulation of histone ubiquitination(GO:0033184) regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.8 7.4 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.8 5.7 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.8 9.7 GO:0014848 urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848)
0.8 3.9 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.8 6.2 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.8 14.7 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.8 4.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.7 19.4 GO:0097503 sialylation(GO:0097503)
0.7 3.7 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.7 14.7 GO:0005513 detection of calcium ion(GO:0005513)
0.7 7.3 GO:0030913 paranodal junction assembly(GO:0030913)
0.7 5.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.7 2.2 GO:1903401 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine transmembrane transport(GO:1903401) L-lysine import into cell(GO:1903410)
0.7 11.5 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.7 11.4 GO:0032836 glomerular basement membrane development(GO:0032836)
0.7 2.1 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.7 3.6 GO:0070166 enamel mineralization(GO:0070166)
0.7 3.5 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.7 5.6 GO:0003338 metanephros morphogenesis(GO:0003338)
0.7 2.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.7 4.8 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.7 22.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.7 10.9 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.7 11.5 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.7 3.3 GO:0060004 reflex(GO:0060004)
0.7 15.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.7 2.0 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.7 9.3 GO:0097264 self proteolysis(GO:0097264)
0.7 5.3 GO:0016926 protein desumoylation(GO:0016926)
0.7 2.6 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.7 9.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.7 3.9 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.6 1.9 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.6 1.9 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.6 1.9 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.6 1.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.6 7.7 GO:0048820 hair follicle maturation(GO:0048820)
0.6 5.9 GO:0048102 autophagic cell death(GO:0048102)
0.6 11.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.6 5.9 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.6 5.3 GO:0046578 regulation of Ras protein signal transduction(GO:0046578)
0.6 1.7 GO:0021997 neural plate axis specification(GO:0021997)
0.6 5.7 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.6 2.3 GO:0015808 L-alanine transport(GO:0015808)
0.6 5.7 GO:0060841 venous blood vessel development(GO:0060841)
0.6 1.7 GO:0009447 putrescine catabolic process(GO:0009447)
0.6 3.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.6 2.2 GO:0007018 microtubule-based movement(GO:0007018)
0.6 6.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.5 1.6 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.5 3.8 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.5 7.6 GO:0021854 hypothalamus development(GO:0021854)
0.5 5.4 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.5 4.3 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.5 3.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 1.6 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.5 9.9 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.5 3.6 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.5 2.6 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.5 4.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.5 31.9 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.5 9.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.5 9.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.5 4.5 GO:0033127 regulation of histone phosphorylation(GO:0033127)
0.5 8.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.5 10.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.5 4.0 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.5 12.3 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.5 2.0 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.5 0.5 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.5 4.9 GO:0008038 neuron recognition(GO:0008038)
0.5 12.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.5 3.3 GO:0034453 microtubule anchoring(GO:0034453)
0.5 12.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.5 15.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.5 1.9 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.5 0.5 GO:0072178 nephric duct development(GO:0072176) nephric duct morphogenesis(GO:0072178)
0.5 8.7 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.5 1.4 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.5 4.1 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.4 13.9 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.4 1.8 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.4 1.8 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.4 4.4 GO:0055123 digestive system development(GO:0055123)
0.4 3.0 GO:0090344 negative regulation of cell aging(GO:0090344)
0.4 6.7 GO:0030030 cell projection organization(GO:0030030)
0.4 1.3 GO:0072284 thyroid-stimulating hormone secretion(GO:0070460) comma-shaped body morphogenesis(GO:0072049) S-shaped body morphogenesis(GO:0072050) metanephric comma-shaped body morphogenesis(GO:0072278) metanephric S-shaped body morphogenesis(GO:0072284) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.4 6.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 2.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.4 1.2 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.4 5.7 GO:0009650 UV protection(GO:0009650)
0.4 3.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.4 3.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.4 2.8 GO:0048710 regulation of astrocyte differentiation(GO:0048710)
0.4 2.4 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.4 9.0 GO:0009435 NAD biosynthetic process(GO:0009435)
0.4 3.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.4 8.5 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.4 2.3 GO:0006196 AMP catabolic process(GO:0006196)
0.4 2.7 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.4 3.0 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.4 20.7 GO:0030516 regulation of axon extension(GO:0030516)
0.4 12.5 GO:0090102 cochlea development(GO:0090102)
0.4 5.1 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.4 9.7 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.4 9.3 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.4 1.4 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.3 4.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.3 2.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.3 15.0 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.3 1.3 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.3