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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HMGA1

Z-value: 0.88

Motif logo

Transcription factors associated with HMGA1

Gene Symbol Gene ID Gene Info
ENSG00000137309.15 high mobility group AT-hook 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMGA1hg19_v2_chr6_+_34204642_34204664-0.235.5e-04Click!

Activity profile of HMGA1 motif

Sorted Z-values of HMGA1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91539918 12.44 ENST00000548218.1
decorin
chr4_+_155484155 11.57 ENST00000509493.1
fibrinogen beta chain
chr1_+_196621002 11.32 ENST00000367429.4
ENST00000439155.2
complement factor H
chr3_-_195310802 10.20 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr12_-_91546926 9.75 ENST00000550758.1
decorin
chr2_+_189839046 8.60 ENST00000304636.3
ENST00000317840.5
collagen, type III, alpha 1
chr4_-_143226979 8.57 ENST00000514525.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr12_-_91573249 7.83 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr1_+_196621156 7.64 ENST00000359637.2
complement factor H
chr12_-_71551652 7.51 ENST00000546561.1
tetraspanin 8
chr14_-_61748550 7.40 ENST00000555868.1
transmembrane protein 30B
chr12_-_91574142 7.10 ENST00000547937.1
decorin
chrX_-_13835461 7.08 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr6_+_153552455 7.00 ENST00000392385.2
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr4_+_74301880 6.80 ENST00000395792.2
ENST00000226359.2
alpha-fetoprotein
chr4_+_74269956 6.70 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
albumin
chr5_-_147211226 6.65 ENST00000296695.5
serine peptidase inhibitor, Kazal type 1
chr4_+_55095264 6.32 ENST00000257290.5
platelet-derived growth factor receptor, alpha polypeptide
chr12_+_12938541 6.07 ENST00000356591.4
apolipoprotein L domain containing 1
chr4_+_88896819 5.84 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
secreted phosphoprotein 1
chr12_-_91505608 5.79 ENST00000266718.4
lumican
chrX_-_73072534 5.77 ENST00000429829.1
X inactive specific transcript (non-protein coding)
chr4_-_88450244 5.73 ENST00000503414.1
SPARC-like 1 (hevin)
chr2_+_1418154 5.68 ENST00000423320.1
ENST00000382198.1
thyroid peroxidase
chr2_-_86333244 5.66 ENST00000263857.6
ENST00000409681.1
polymerase (RNA) I polypeptide A, 194kDa
chr1_-_57045228 5.65 ENST00000371250.3
phosphatidic acid phosphatase type 2B
chr4_-_155533787 5.47 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
fibrinogen gamma chain
chr4_+_74275057 5.39 ENST00000511370.1
albumin
chrX_+_103031421 5.39 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
proteolipid protein 1
chr5_-_147211190 5.22 ENST00000510027.2
serine peptidase inhibitor, Kazal type 1
chr11_+_93479588 5.16 ENST00000526335.1
chromosome 11 open reading frame 54
chr4_+_155484103 5.03 ENST00000302068.4
fibrinogen beta chain
chr8_-_82395461 5.02 ENST00000256104.4
fatty acid binding protein 4, adipocyte
chr3_+_148508845 4.82 ENST00000491148.1
carboxypeptidase B1 (tissue)
chr7_-_16844611 4.76 ENST00000401412.1
ENST00000419304.2
anterior gradient 2
chr10_-_5046042 4.57 ENST00000421196.3
ENST00000455190.1
aldo-keto reductase family 1, member C2
chr4_-_134070250 4.51 ENST00000505289.1
ENST00000509715.1
RP11-9G1.3
chr7_+_134430212 4.35 ENST00000436461.2
caldesmon 1
chr2_-_152589670 4.24 ENST00000604864.1
ENST00000603639.1
nebulin
chr11_-_111781554 4.23 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chr7_+_94023873 4.22 ENST00000297268.6
collagen, type I, alpha 2
chr1_+_89829610 4.05 ENST00000370456.4
ENST00000535065.1
guanylate binding protein family, member 6
chr15_-_99789736 4.02 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
tetratricopeptide repeat domain 23
chr2_-_238323007 3.98 ENST00000295550.4
collagen, type VI, alpha 3
chr7_+_75932863 3.88 ENST00000429938.1
heat shock 27kDa protein 1
chr19_-_10333842 3.84 ENST00000317726.4
CTD-2369P2.2
chr17_-_66951474 3.79 ENST00000269080.2
ATP-binding cassette, sub-family A (ABC1), member 8
chr1_+_104159999 3.77 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr13_-_45010939 3.76 ENST00000261489.2
TSC22 domain family, member 1
chr17_-_64216748 3.75 ENST00000585162.1
apolipoprotein H (beta-2-glycoprotein I)
chr9_-_21202204 3.47 ENST00000239347.3
interferon, alpha 7
chr4_-_186696425 3.43 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chrX_-_13835147 3.41 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr3_+_109128961 3.39 ENST00000489670.1
RP11-702L6.4
chr8_+_22224811 3.39 ENST00000381237.1
solute carrier family 39 (zinc transporter), member 14
chr3_-_167191814 3.38 ENST00000466903.1
ENST00000264677.4
serpin peptidase inhibitor, clade I (pancpin), member 2
chr1_-_237167718 3.34 ENST00000464121.2
metallothionein 1H-like 1
chr4_-_186877806 3.27 ENST00000355634.5
sorbin and SH3 domain containing 2
chr17_-_64225508 3.24 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr7_+_20686946 3.24 ENST00000443026.2
ENST00000406935.1
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr5_+_140739537 3.23 ENST00000522605.1
protocadherin gamma subfamily B, 2
chr21_-_43735628 3.21 ENST00000291525.10
ENST00000518498.1
trefoil factor 3 (intestinal)
chr17_-_10452929 3.14 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
myosin, heavy chain 2, skeletal muscle, adult
chr11_-_13517565 3.10 ENST00000282091.1
ENST00000529816.1
parathyroid hormone
chr12_+_101988627 2.99 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
myosin binding protein C, slow type
chr5_+_137203465 2.97 ENST00000239926.4
myotilin
chr6_-_52859046 2.94 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
glutathione S-transferase alpha 4
chr6_-_52705641 2.93 ENST00000370989.2
glutathione S-transferase alpha 5
chr2_+_79252834 2.90 ENST00000409471.1
regenerating islet-derived 3 gamma
chr17_+_41857793 2.87 ENST00000449302.3
chromosome 17 open reading frame 105
chr4_-_186697044 2.84 ENST00000437304.2
sorbin and SH3 domain containing 2
chr9_-_95298314 2.82 ENST00000344604.5
ENST00000375540.1
extracellular matrix protein 2, female organ and adipocyte specific
chr8_-_17555164 2.81 ENST00000297488.6
microtubule associated tumor suppressor 1
chr11_-_2906979 2.80 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr13_-_38172863 2.77 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
periostin, osteoblast specific factor
chr2_+_196313239 2.74 ENST00000413290.1
AC064834.1
chr4_+_71248795 2.74 ENST00000304915.3
submaxillary gland androgen regulated protein 3B
chr9_+_71944241 2.72 ENST00000257515.8
family with sequence similarity 189, member A2
chr7_+_134551583 2.69 ENST00000435928.1
caldesmon 1
chr9_+_706842 2.59 ENST00000382293.3
KN motif and ankyrin repeat domains 1
chr3_+_109128837 2.52 ENST00000497996.1
RP11-702L6.4
chr19_+_41509851 2.51 ENST00000593831.1
ENST00000330446.5
cytochrome P450, family 2, subfamily B, polypeptide 6
chr11_-_2162468 2.50 ENST00000434045.2
insulin-like growth factor 2 (somatomedin A)
chr9_-_98079965 2.50 ENST00000289081.3
Fanconi anemia, complementation group C
chr12_+_54422142 2.49 ENST00000243108.4
homeobox C6
chr18_-_64271363 2.44 ENST00000262150.2
cadherin 19, type 2
chr15_+_80733570 2.41 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
aryl-hydrocarbon receptor nuclear translocator 2
chr14_-_90798418 2.40 ENST00000354366.3
NRDE-2, necessary for RNA interference, domain containing
chr5_-_160279207 2.39 ENST00000327245.5
ATPase, class V, type 10B
chr10_-_21661870 2.37 ENST00000433460.1
RP11-275N1.1
chr14_-_82000140 2.34 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
sel-1 suppressor of lin-12-like (C. elegans)
chr4_-_100242549 2.34 ENST00000305046.8
ENST00000394887.3
alcohol dehydrogenase 1B (class I), beta polypeptide
chr3_-_149095652 2.33 ENST00000305366.3
transmembrane 4 L six family member 1
chr12_-_102591604 2.32 ENST00000329406.4
pro-melanin-concentrating hormone
chr9_-_123812542 2.31 ENST00000223642.1
complement component 5
chr7_-_99277610 2.30 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
cytochrome P450, family 3, subfamily A, polypeptide 5
chr17_-_47755338 2.30 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
speckle-type POZ protein
chr2_+_79252822 2.30 ENST00000272324.5
regenerating islet-derived 3 gamma
chr10_+_114710516 2.29 ENST00000542695.1
ENST00000346198.4
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr10_-_69597810 2.27 ENST00000483798.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr12_+_14572070 2.24 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
activating transcription factor 7 interacting protein
chr10_+_92980517 2.22 ENST00000336126.5
polycomb group ring finger 5
chr3_+_149191723 2.22 ENST00000305354.4
transmembrane 4 L six family member 4
chr5_-_41261540 2.19 ENST00000263413.3
complement component 6
chr5_+_137203557 2.17 ENST00000515645.1
myotilin
chr2_-_211168332 2.16 ENST00000341685.4
myosin, light chain 1, alkali; skeletal, fast
chr9_-_21187598 2.15 ENST00000421715.1
interferon, alpha 4
chr5_+_118812237 2.14 ENST00000513628.1
hydroxysteroid (17-beta) dehydrogenase 4
chr1_+_215740709 2.13 ENST00000259154.4
potassium channel tetramerization domain containing 3
chr5_+_140762268 2.13 ENST00000518325.1
protocadherin gamma subfamily A, 7
chr12_-_111358372 2.11 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chr5_+_137203541 2.07 ENST00000421631.2
myotilin
chr7_-_55930443 2.05 ENST00000388975.3
septin 14
chr1_-_153013588 2.04 ENST00000360379.3
small proline-rich protein 2D
chr14_-_21270995 2.04 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
ribonuclease, RNase A family, 1 (pancreatic)
chr7_-_152373216 2.00 ENST00000359321.1
X-ray repair complementing defective repair in Chinese hamster cells 2
chr12_-_54582655 2.00 ENST00000504338.1
ENST00000514685.1
ENST00000504797.1
ENST00000513838.1
ENST00000505128.1
ENST00000337581.3
ENST00000503306.1
ENST00000243112.5
ENST00000514196.1
ENST00000506169.1
ENST00000507904.1
ENST00000508394.2
single-strand-selective monofunctional uracil-DNA glycosylase 1
chr17_+_68071458 1.99 ENST00000589377.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr2_+_17721920 1.96 ENST00000295156.4
visinin-like 1
chr3_+_69915385 1.95 ENST00000314589.5
microphthalmia-associated transcription factor
chr2_-_217560248 1.94 ENST00000233813.4
insulin-like growth factor binding protein 5
chr14_-_70883708 1.93 ENST00000256366.4
synaptojanin 2 binding protein
chr20_-_23731893 1.92 ENST00000398402.1
cystatin SN
chr6_-_46293378 1.90 ENST00000330430.6
regulator of calcineurin 2
chr5_+_118812294 1.88 ENST00000509514.1
hydroxysteroid (17-beta) dehydrogenase 4
chr3_-_50340996 1.88 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
hyaluronoglucosaminidase 1
chrX_+_65384052 1.87 ENST00000336279.5
ENST00000458621.1
hephaestin
chr4_-_89744314 1.86 ENST00000508369.1
family with sequence similarity 13, member A
chr12_-_16759711 1.86 ENST00000447609.1
LIM domain only 3 (rhombotin-like 2)
chr5_+_140753444 1.85 ENST00000517434.1
protocadherin gamma subfamily A, 6
chr4_-_57547454 1.83 ENST00000556376.2
HOP homeobox
chr16_-_71610985 1.82 ENST00000355962.4
tyrosine aminotransferase
chr17_-_6915646 1.80 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
Uncharacterized protein
chr1_+_180601139 1.80 ENST00000367590.4
ENST00000367589.3
xenotropic and polytropic retrovirus receptor 1
chr6_+_126102292 1.79 ENST00000368357.3
nuclear receptor coactivator 7
chr7_-_120498357 1.79 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr6_-_151773232 1.78 ENST00000444024.1
ENST00000367303.4
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr11_+_22696314 1.74 ENST00000532398.1
ENST00000433790.1
growth arrest-specific 2
chr12_+_32655048 1.72 ENST00000427716.2
ENST00000266482.3
FYVE, RhoGEF and PH domain containing 4
chr6_+_161123270 1.71 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
plasminogen
chr12_+_20963632 1.71 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr12_-_102872317 1.69 ENST00000424202.2
insulin-like growth factor 1 (somatomedin C)
chr2_+_145780767 1.69 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
testis expressed 41 (non-protein coding)
chr12_+_20963647 1.65 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr3_-_148939835 1.65 ENST00000264613.6
ceruloplasmin (ferroxidase)
chr10_-_62149433 1.65 ENST00000280772.2
ankyrin 3, node of Ranvier (ankyrin G)
chr2_-_206950781 1.61 ENST00000403263.1
INO80 complex subunit D
chr11_+_1940925 1.61 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
troponin T type 3 (skeletal, fast)
chr5_-_125930929 1.61 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
aldehyde dehydrogenase 7 family, member A1
chr13_-_41240717 1.60 ENST00000379561.5
forkhead box O1
chr1_+_152881014 1.59 ENST00000368764.3
ENST00000392667.2
involucrin
chr2_-_69870747 1.59 ENST00000409068.1
AP2 associated kinase 1
chr15_+_49462397 1.59 ENST00000396509.2
galactokinase 2
chr5_-_107703556 1.59 ENST00000496714.1
F-box and leucine-rich repeat protein 17
chr6_+_151646800 1.58 ENST00000354675.6
A kinase (PRKA) anchor protein 12
chr2_-_188312971 1.58 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
calcitonin receptor-like
chr10_-_69597915 1.58 ENST00000225171.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr12_+_21207503 1.57 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr4_-_47983519 1.56 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chr3_+_111717600 1.55 ENST00000273368.4
transgelin 3
chr15_-_55657428 1.55 ENST00000568543.1
cell cycle progression 1
chr12_+_8995832 1.54 ENST00000541459.1
alpha-2-macroglobulin-like 1
chr9_-_21142144 1.50 ENST00000380229.2
interferon, omega 1
chr12_+_101988774 1.50 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
myosin binding protein C, slow type
chr4_-_100212132 1.48 ENST00000209668.2
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr9_-_21995249 1.48 ENST00000494262.1
cyclin-dependent kinase inhibitor 2A
chrX_+_138612889 1.47 ENST00000218099.2
ENST00000394090.2
coagulation factor IX
chr20_-_14318248 1.46 ENST00000378053.3
ENST00000341420.4
fibronectin leucine rich transmembrane protein 3
chr10_-_101825151 1.45 ENST00000441382.1
carboxypeptidase N, polypeptide 1
chr4_-_89744365 1.44 ENST00000513837.1
ENST00000503556.1
family with sequence similarity 13, member A
chr7_-_137028498 1.43 ENST00000393083.2
pleiotrophin
chr13_+_73629107 1.43 ENST00000539231.1
Kruppel-like factor 5 (intestinal)
chr10_+_118305435 1.42 ENST00000369221.2
pancreatic lipase
chr15_+_49462434 1.41 ENST00000558145.1
ENST00000543495.1
ENST00000544523.1
ENST00000560138.1
galactokinase 2
chrX_-_102941596 1.41 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
mortality factor 4 like 2
chr3_-_124653579 1.41 ENST00000478191.1
ENST00000311075.3
mucin 13, cell surface associated
chr17_+_3379284 1.41 ENST00000263080.2
aspartoacylase
chr2_-_87248975 1.39 ENST00000409310.2
ENST00000355705.3
plasminogen-like B1
chr14_+_39736582 1.38 ENST00000556148.1
ENST00000348007.3
CTAGE family, member 5
chr3_+_69985792 1.37 ENST00000531774.1
microphthalmia-associated transcription factor
chr4_+_88754069 1.37 ENST00000395102.4
ENST00000497649.2
matrix extracellular phosphoglycoprotein
chr3_-_46608010 1.37 ENST00000395905.3
leucine rich repeat containing 2
chr13_+_113760098 1.37 ENST00000346342.3
ENST00000541084.1
ENST00000375581.3
coagulation factor VII (serum prothrombin conversion accelerator)
chr7_-_99381798 1.36 ENST00000415003.1
ENST00000354593.2
cytochrome P450, family 3, subfamily A, polypeptide 4
chr7_+_134528635 1.36 ENST00000445569.2
caldesmon 1
chr5_+_66254698 1.35 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
microtubule associated serine/threonine kinase family member 4
chr2_-_224467093 1.33 ENST00000305409.2
secretogranin II
chr2_+_210517895 1.32 ENST00000447185.1
microtubule-associated protein 2
chr7_-_99381884 1.32 ENST00000336411.2
cytochrome P450, family 3, subfamily A, polypeptide 4
chr2_+_172543919 1.32 ENST00000452242.1
ENST00000340296.4
dynein, cytoplasmic 1, intermediate chain 2
chr12_+_19358228 1.31 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr13_+_49684445 1.30 ENST00000398316.3
fibronectin type III domain containing 3A
chr6_+_26158343 1.27 ENST00000377777.4
ENST00000289316.2
histone cluster 1, H2bd
chr6_+_134758827 1.27 ENST00000431422.1
long intergenic non-protein coding RNA 1010
chr3_+_171561127 1.26 ENST00000334567.5
ENST00000450693.1
transmembrane protein 212
chrX_+_65384182 1.26 ENST00000441993.2
ENST00000419594.1
hephaestin
chr2_+_157330081 1.24 ENST00000409674.1
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr4_-_89744457 1.24 ENST00000395002.2
family with sequence similarity 13, member A
chr5_+_92919043 1.22 ENST00000327111.3
nuclear receptor subfamily 2, group F, member 1
chr8_-_110620284 1.21 ENST00000529690.1
syntabulin (syntaxin-interacting)

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.1 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
3.4 10.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
3.1 37.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
2.1 6.3 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
2.0 11.9 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
1.9 5.8 GO:0035938 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
1.7 5.2 GO:0044278 cell wall disruption in other organism(GO:0044278)
1.7 16.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.4 5.7 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
1.2 5.0 GO:0009822 alkaloid catabolic process(GO:0009822)
1.1 2.2 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.1 8.7 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
1.1 8.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.1 4.2 GO:0007525 somatic muscle development(GO:0007525)
1.0 3.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
1.0 9.7 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.0 3.9 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.9 22.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.9 2.8 GO:1990523 bone regeneration(GO:1990523)
0.9 2.6 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.8 5.9 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.8 3.2 GO:0048749 compound eye development(GO:0048749)
0.8 4.6 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.7 4.3 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.7 1.4 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.7 4.0 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.7 4.6 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.6 1.9 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.6 1.9 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.6 7.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.5 1.6 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.5 6.1 GO:0042118 endothelial cell activation(GO:0042118)
0.5 1.4 GO:0006533 aspartate catabolic process(GO:0006533)
0.5 3.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.5 6.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.4 1.7 GO:0032571 response to vitamin K(GO:0032571)
0.4 8.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.4 1.6 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.4 2.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.4 1.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 13.1 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.4 2.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.4 3.8 GO:0042908 xenobiotic transport(GO:0042908)
0.4 1.1 GO:0003218 cardiac left ventricle formation(GO:0003218) cell migration involved in vasculogenesis(GO:0035441)
0.4 2.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 3.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.3 5.0 GO:0071285 cellular response to lithium ion(GO:0071285)
0.3 2.0 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.3 1.0 GO:0006711 estrogen catabolic process(GO:0006711)
0.3 3.0 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.3 5.5 GO:0031639 plasminogen activation(GO:0031639)
0.3 1.0 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.3 1.6 GO:1902617 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) response to fluoride(GO:1902617)
0.3 4.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 1.0 GO:0003099 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.3 1.0 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.3 5.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.3 4.4 GO:0043589 skin morphogenesis(GO:0043589)
0.3 1.9 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.3 1.5 GO:0030070 insulin processing(GO:0030070)
0.3 0.9 GO:0002933 lipid hydroxylation(GO:0002933)
0.3 2.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.3 2.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.3 0.8 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.3 1.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.3 1.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 2.0 GO:0019563 glycerol catabolic process(GO:0019563)
0.3 2.5 GO:0006069 ethanol oxidation(GO:0006069)
0.2 3.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 0.7 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 0.7 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 1.9 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 4.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 1.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.2 0.9 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 1.6 GO:0042426 choline catabolic process(GO:0042426)
0.2 5.7 GO:0006590 thyroid hormone generation(GO:0006590)
0.2 0.7 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.2 0.7 GO:0032252 secretory granule localization(GO:0032252)
0.2 1.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 1.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 2.3 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 1.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 1.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.2 1.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 0.4 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 0.8 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.2 0.6 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.2 1.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 0.5 GO:0051697 protein delipidation(GO:0051697)
0.2 1.6 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 0.7 GO:0071231 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) cellular response to folic acid(GO:0071231)
0.2 0.2 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.2 10.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 5.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 1.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 1.0 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.2 0.5 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.2 2.0 GO:0045008 depyrimidination(GO:0045008)
0.2 3.0 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.6 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 7.0 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.7 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 3.7 GO:0006825 copper ion transport(GO:0006825)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 0.6 GO:1900738 psychomotor behavior(GO:0036343) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.3 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 0.6 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.1 0.9 GO:0015705 iodide transport(GO:0015705)
0.1 0.4 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 1.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 2.4 GO:0070168 negative regulation of bone mineralization(GO:0030502) negative regulation of biomineral tissue development(GO:0070168)
0.1 0.5 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 3.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.8 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.9 GO:0033084 regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 1.9 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 18.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.4 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.6 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 2.4 GO:0016246 RNA interference(GO:0016246)
0.1 7.2 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 1.7 GO:0010842 retina layer formation(GO:0010842)
0.1 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.5 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 1.3 GO:0060973 cell migration involved in heart development(GO:0060973)
0.1 2.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 1.4 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 2.4 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 1.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.7 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 2.9 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 0.5 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 1.1 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.1 2.9 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 2.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 1.3 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.4 GO:0010513 regulation of phosphatidylinositol biosynthetic process(GO:0010511) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.7 GO:0070166 enamel mineralization(GO:0070166) regulation of tooth mineralization(GO:0070170)
0.1 0.9 GO:0009650 UV protection(GO:0009650)
0.1 0.2 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.1 1.8 GO:0010107 potassium ion import(GO:0010107)
0.1 0.3 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.5 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) membrane depolarization during SA node cell action potential(GO:0086046)
0.1 1.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.6 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 3.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.9 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 5.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.4 GO:0034378 chylomicron assembly(GO:0034378)
0.1 3.1 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 0.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.7 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 2.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 0.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 1.0 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.1 0.4 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.5 GO:0051552 flavone metabolic process(GO:0051552)
0.1 1.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.6 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.1 0.2 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.6 GO:0019627 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.0 1.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425) valyl-tRNA aminoacylation(GO:0006438)
0.0 2.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.5 GO:0061053 somite development(GO:0061053)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.9 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 2.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 1.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 3.1 GO:0007586 digestion(GO:0007586)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 2.0 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.7 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.9 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.9 GO:0000305 response to oxygen radical(GO:0000305)
0.0 1.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.5 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.8 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 1.7 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.0 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 6.9 GO:0006936 muscle contraction(GO:0006936)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 3.7 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.7 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.6 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.1 GO:0060687 antral ovarian follicle growth(GO:0001547) prostate epithelial cord elongation(GO:0060523) regulation of branching involved in prostate gland morphogenesis(GO:0060687) prostate gland morphogenetic growth(GO:0060737)
0.0 0.4 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.2 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.2 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.2 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 41.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.6 21.4 GO:0005577 fibrinogen complex(GO:0005577)
1.6 18.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.0 3.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.7 4.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.6 5.7 GO:0005579 membrane attack complex(GO:0005579)
0.6 8.4 GO:0030478 actin cap(GO:0030478)
0.5 2.3 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.4 2.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 3.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.4 6.3 GO:0097512 cardiac myofibril(GO:0097512)
0.4 7.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 1.1 GO:0097679 other organism cytoplasm(GO:0097679)
0.4 2.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.3 2.0 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 5.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 1.7 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2 2.1 GO:0016013 syntrophin complex(GO:0016013)
0.2 2.4 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.7 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 1.1 GO:0070847 core mediator complex(GO:0070847)
0.2 1.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 1.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 4.8 GO:0032982 myosin filament(GO:0032982)
0.2 0.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 2.2 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.6 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 0.7 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 22.8 GO:0030018 Z disc(GO:0030018)
0.1 13.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.1 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.6 GO:0005927 muscle tendon junction(GO:0005927)
0.1 1.0 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 9.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 1.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 5.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.2 GO:1990357 terminal web(GO:1990357)
0.1 1.2 GO:0097433 dense body(GO:0097433)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.3 GO:0031045 dense core granule(GO:0031045)
0.1 1.6 GO:0005861 troponin complex(GO:0005861)
0.1 1.0 GO:0033270 paranode region of axon(GO:0033270)
0.1 6.4 GO:0005811 lipid particle(GO:0005811)
0.1 2.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 6.0 GO:0005902 microvillus(GO:0005902)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 2.9 GO:0001533 cornified envelope(GO:0001533)
0.1 17.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 2.8 GO:0043195 terminal bouton(GO:0043195)
0.0 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 48.0 GO:0005615 extracellular space(GO:0005615)
0.0 7.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 5.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.7 GO:0031904 endosome lumen(GO:0031904)
0.0 4.1 GO:0001726 ruffle(GO:0001726)
0.0 0.7 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.4 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 3.7 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.8 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.9 9.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
1.4 7.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.3 3.9 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
1.1 12.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.0 3.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.9 5.7 GO:0004447 iodide peroxidase activity(GO:0004447)
0.9 3.8 GO:0016160 amylase activity(GO:0016160)
0.9 2.8 GO:0070052 collagen V binding(GO:0070052)
0.9 2.7 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.9 7.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.8 19.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.8 12.4 GO:0015643 toxic substance binding(GO:0015643)
0.8 4.6 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.7 46.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.7 4.0 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.6 8.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.6 1.8 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.6 2.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.5 5.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.5 1.6 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.5 4.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 2.0 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.5 1.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.5 1.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.4 5.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 2.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.4 8.7 GO:0002162 dystroglycan binding(GO:0002162)
0.4 1.6 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.4 1.6 GO:0004948 calcitonin receptor activity(GO:0004948)
0.3 2.0 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 2.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.3 29.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 1.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 1.0 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.3 1.0 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.3 7.3 GO:0005523 tropomyosin binding(GO:0005523)
0.3 1.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 5.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.3 1.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.3 1.2 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.3 5.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.3 5.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 0.8 GO:0005549 odorant binding(GO:0005549)
0.2 0.7 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.2 0.7 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 4.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 3.0 GO:0001968 fibronectin binding(GO:0001968)
0.2 0.7 GO:0005148 prolactin receptor binding(GO:0005148)
0.2 4.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 1.5 GO:1990405 protein antigen binding(GO:1990405)
0.2 1.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.2 1.5 GO:0045499 chemorepellent activity(GO:0045499)
0.2 1.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 21.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 3.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 10.5 GO:0015485 cholesterol binding(GO:0015485)
0.2 0.9 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 2.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 0.9 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.2 2.0 GO:0000150 recombinase activity(GO:0000150)
0.2 2.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 0.7 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 1.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.2 0.5 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.2 3.1 GO:0048018 receptor agonist activity(GO:0048018)
0.2 1.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.6 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 1.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 4.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 6.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 3.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 6.6 GO:0005518 collagen binding(GO:0005518)
0.1 0.5 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 13.0 GO:0051087 chaperone binding(GO:0051087)
0.1 1.6 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.8 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.9 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 2.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.7 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 2.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 2.7 GO:0030546 receptor activator activity(GO:0030546)
0.1 0.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 1.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.3 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 3.4 GO:0000146 microfilament motor activity(GO:0000146)
0.1 1.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.0 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
0.1 0.9 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.3 GO:0035473 lipase binding(GO:0035473)
0.1 4.3 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.8 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.2 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1 0.9 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 1.1 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.1 2.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.2 GO:0042805 actinin binding(GO:0042805)
0.1 1.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 3.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 7.8 GO:0005178 integrin binding(GO:0005178)
0.1 2.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.8 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.5 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 1.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 2.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 2.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 3.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.1 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.6 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 2.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 10.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.0 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 5.1 GO:0005525 GTP binding(GO:0005525)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0005507 copper ion binding(GO:0005507)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 41.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.4 44.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.3 20.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 2.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 5.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 11.6 PID AP1 PATHWAY AP-1 transcription factor network
0.1 3.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 15.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 5.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 1.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 1.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.9 PID ATR PATHWAY ATR signaling pathway
0.0 2.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.1 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 9.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 4.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 5.7 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.3 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 39.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.3 21.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
1.0 16.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.8 21.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.8 3.9 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.6 9.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.5 8.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.4 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.4 5.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 2.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 2.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 3.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.3 17.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 5.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 4.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 6.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 5.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 7.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 15.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 7.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 4.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 8.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 5.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 5.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 5.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 2.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 2.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.0 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.1 2.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.8 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 8.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.0 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.1 0.7 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 3.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 2.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.0 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 1.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 4.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.1 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 2.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.5 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 3.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 1.2 REACTOME SIGNALING BY FGFR MUTANTS Genes involved in Signaling by FGFR mutants
0.0 1.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 2.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis