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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for HNF1A_HNF1B
Z-value: 2.00
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Transcription factors associated with HNF1A_HNF1B
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HNF1A
|
ENSG00000135100.13 | HNF1 homeobox A |
|
HNF1B
|
ENSG00000108753.8 | HNF1 homeobox B |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HNF1A | hg19_v2_chr12_+_121416489_121416552 | 0.52 | 1.0e-16 | Click! |
Activity profile of HNF1A_HNF1B motif
Sorted Z-values of HNF1A_HNF1B motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_-_64225508 | 56.35 |
ENST00000205948.6
|
APOH
|
apolipoprotein H (beta-2-glycoprotein I) |
| chr4_-_72649763 | 56.27 |
ENST00000513476.1
|
GC
|
group-specific component (vitamin D binding protein) |
| chr4_+_74301880 | 45.80 |
ENST00000395792.2
ENST00000226359.2 |
AFP
|
alpha-fetoprotein |
| chr4_+_155484155 | 41.46 |
ENST00000509493.1
|
FGB
|
fibrinogen beta chain |
| chr19_-_36304201 | 37.30 |
ENST00000301175.3
|
PRODH2
|
proline dehydrogenase (oxidase) 2 |
| chr14_-_94854926 | 37.12 |
ENST00000402629.1
ENST00000556091.1 ENST00000554720.1 |
SERPINA1
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| chr6_+_161123270 | 37.00 |
ENST00000366924.2
ENST00000308192.9 ENST00000418964.1 |
PLG
|
plasminogen |
| chr4_-_155511887 | 36.16 |
ENST00000302053.3
ENST00000403106.3 |
FGA
|
fibrinogen alpha chain |
| chr4_+_155484103 | 34.96 |
ENST00000302068.4
|
FGB
|
fibrinogen beta chain |
| chr4_+_74269956 | 31.37 |
ENST00000295897.4
ENST00000415165.2 ENST00000503124.1 ENST00000509063.1 ENST00000401494.3 |
ALB
|
albumin |
| chr2_+_234601512 | 31.01 |
ENST00000305139.6
|
UGT1A6
|
UDP glucuronosyltransferase 1 family, polypeptide A6 |
| chr2_+_234668894 | 30.43 |
ENST00000305208.5
ENST00000608383.1 ENST00000360418.3 |
UGT1A8
UGT1A1
|
UDP glucuronosyltransferase 1 family, polypeptide A1 UDP glucuronosyltransferase 1 family, polypeptide A8 |
| chr9_-_123812542 | 29.58 |
ENST00000223642.1
|
C5
|
complement component 5 |
| chr7_-_50633078 | 26.77 |
ENST00000444124.2
|
DDC
|
dopa decarboxylase (aromatic L-amino acid decarboxylase) |
| chr15_+_58724184 | 26.73 |
ENST00000433326.2
|
LIPC
|
lipase, hepatic |
| chr19_+_50016610 | 25.12 |
ENST00000596975.1
|
FCGRT
|
Fc fragment of IgG, receptor, transporter, alpha |
| chr4_+_74347400 | 22.53 |
ENST00000226355.3
|
AFM
|
afamin |
| chr10_+_5135981 | 22.23 |
ENST00000380554.3
|
AKR1C3
|
aldo-keto reductase family 1, member C3 |
| chr2_+_234637754 | 21.75 |
ENST00000482026.1
ENST00000609767.1 |
UGT1A3
UGT1A1
|
UDP glucuronosyltransferase 1 family, polypeptide A3 UDP glucuronosyltransferase 1 family, polypeptide A8 |
| chr5_+_176513868 | 21.24 |
ENST00000292408.4
|
FGFR4
|
fibroblast growth factor receptor 4 |
| chr1_+_207277590 | 21.18 |
ENST00000367070.3
|
C4BPA
|
complement component 4 binding protein, alpha |
| chr2_+_88047606 | 20.63 |
ENST00000359481.4
|
PLGLB2
|
plasminogen-like B2 |
| chr8_-_17752996 | 20.12 |
ENST00000381841.2
ENST00000427924.1 |
FGL1
|
fibrinogen-like 1 |
| chr6_-_161085291 | 19.96 |
ENST00000316300.5
|
LPA
|
lipoprotein, Lp(a) |
| chr2_-_88427568 | 19.46 |
ENST00000393750.3
ENST00000295834.3 |
FABP1
|
fatty acid binding protein 1, liver |
| chr7_+_45927956 | 17.97 |
ENST00000275525.3
ENST00000457280.1 |
IGFBP1
|
insulin-like growth factor binding protein 1 |
| chr14_-_94759408 | 17.57 |
ENST00000554723.1
|
SERPINA10
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
| chr2_-_87248975 | 17.53 |
ENST00000409310.2
ENST00000355705.3 |
PLGLB1
|
plasminogen-like B1 |
| chr5_+_176513895 | 17.20 |
ENST00000503708.1
ENST00000393648.2 ENST00000514472.1 ENST00000502906.1 ENST00000292410.3 ENST00000510911.1 |
FGFR4
|
fibroblast growth factor receptor 4 |
| chr14_-_94759361 | 16.93 |
ENST00000393096.1
|
SERPINA10
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
| chr14_-_94759595 | 16.70 |
ENST00000261994.4
|
SERPINA10
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
| chr10_+_115312766 | 16.33 |
ENST00000351270.3
|
HABP2
|
hyaluronan binding protein 2 |
| chr7_+_45928079 | 16.17 |
ENST00000468955.1
|
IGFBP1
|
insulin-like growth factor binding protein 1 |
| chr3_+_186383741 | 15.94 |
ENST00000232003.4
|
HRG
|
histidine-rich glycoprotein |
| chr4_+_3443614 | 15.79 |
ENST00000382774.3
ENST00000511533.1 |
HGFAC
|
HGF activator |
| chr19_+_50016411 | 15.73 |
ENST00000426395.3
ENST00000600273.1 ENST00000599988.1 |
FCGRT
|
Fc fragment of IgG, receptor, transporter, alpha |
| chr22_-_30970560 | 15.52 |
ENST00000402369.1
ENST00000406361.1 |
GAL3ST1
|
galactose-3-O-sulfotransferase 1 |
| chr11_+_64323098 | 15.30 |
ENST00000301891.4
|
SLC22A11
|
solute carrier family 22 (organic anion/urate transporter), member 11 |
| chr6_-_25930819 | 15.25 |
ENST00000360488.3
|
SLC17A2
|
solute carrier family 17, member 2 |
| chr14_+_95027772 | 14.98 |
ENST00000555095.1
ENST00000298841.5 ENST00000554220.1 ENST00000553780.1 |
SERPINA4
SERPINA5
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| chr14_+_65171099 | 14.97 |
ENST00000247226.7
|
PLEKHG3
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| chr12_-_91574142 | 14.44 |
ENST00000547937.1
|
DCN
|
decorin |
| chr19_+_11350278 | 14.35 |
ENST00000252453.8
|
C19orf80
|
chromosome 19 open reading frame 80 |
| chr17_+_41052808 | 14.10 |
ENST00000592383.1
ENST00000253801.2 ENST00000585489.1 |
G6PC
|
glucose-6-phosphatase, catalytic subunit |
| chr14_+_21156915 | 13.92 |
ENST00000397990.4
ENST00000555597.1 |
ANG
RNASE4
|
angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4 |
| chr17_+_1646130 | 13.91 |
ENST00000453066.1
ENST00000324015.3 ENST00000450523.2 ENST00000453723.1 ENST00000382061.4 |
SERPINF2
|
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
| chr20_+_42187682 | 13.89 |
ENST00000373092.3
ENST00000373077.1 |
SGK2
|
serum/glucocorticoid regulated kinase 2 |
| chr6_-_25930904 | 13.86 |
ENST00000377850.3
|
SLC17A2
|
solute carrier family 17, member 2 |
| chr9_-_98079965 | 13.23 |
ENST00000289081.3
|
FANCC
|
Fanconi anemia, complementation group C |
| chr11_-_117695449 | 12.71 |
ENST00000292079.2
|
FXYD2
|
FXYD domain containing ion transport regulator 2 |
| chr4_-_110723335 | 12.33 |
ENST00000394634.2
|
CFI
|
complement factor I |
| chr1_+_17906970 | 12.17 |
ENST00000375415.1
|
ARHGEF10L
|
Rho guanine nucleotide exchange factor (GEF) 10-like |
| chr10_+_135340859 | 12.10 |
ENST00000252945.3
ENST00000421586.1 ENST00000418356.1 |
CYP2E1
|
cytochrome P450, family 2, subfamily E, polypeptide 1 |
| chr11_+_46740730 | 11.86 |
ENST00000311907.5
ENST00000530231.1 ENST00000442468.1 |
F2
|
coagulation factor II (thrombin) |
| chr6_-_52628271 | 11.86 |
ENST00000493422.1
|
GSTA2
|
glutathione S-transferase alpha 2 |
| chr4_-_100212132 | 11.80 |
ENST00000209668.2
|
ADH1A
|
alcohol dehydrogenase 1A (class I), alpha polypeptide |
| chr20_+_42187608 | 11.61 |
ENST00000373100.1
|
SGK2
|
serum/glucocorticoid regulated kinase 2 |
| chr4_-_110723194 | 11.60 |
ENST00000394635.3
|
CFI
|
complement factor I |
| chr14_-_57960545 | 10.92 |
ENST00000526336.1
ENST00000216445.3 |
C14orf105
|
chromosome 14 open reading frame 105 |
| chr2_+_234627424 | 10.58 |
ENST00000373409.3
|
UGT1A4
|
UDP glucuronosyltransferase 1 family, polypeptide A4 |
| chr11_+_64323156 | 10.49 |
ENST00000377585.3
|
SLC22A11
|
solute carrier family 22 (organic anion/urate transporter), member 11 |
| chrX_-_105282712 | 10.24 |
ENST00000372563.1
|
SERPINA7
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
| chr8_-_70745575 | 10.16 |
ENST00000524945.1
|
SLCO5A1
|
solute carrier organic anion transporter family, member 5A1 |
| chr9_-_94712434 | 9.97 |
ENST00000375708.3
|
ROR2
|
receptor tyrosine kinase-like orphan receptor 2 |
| chr7_-_44580861 | 9.91 |
ENST00000546276.1
ENST00000289547.4 ENST00000381160.3 ENST00000423141.1 |
NPC1L1
|
NPC1-like 1 |
| chr16_+_20462783 | 9.83 |
ENST00000574251.1
ENST00000576361.1 ENST00000417235.2 ENST00000573854.1 ENST00000424070.1 ENST00000536134.1 ENST00000219054.6 ENST00000575690.1 ENST00000571894.1 |
ACSM2A
|
acyl-CoA synthetase medium-chain family member 2A |
| chr4_-_110723134 | 9.81 |
ENST00000510800.1
ENST00000512148.1 |
CFI
|
complement factor I |
| chr14_+_65171315 | 9.67 |
ENST00000394691.1
|
PLEKHG3
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| chr21_-_47575481 | 9.62 |
ENST00000291670.5
ENST00000397748.1 ENST00000359679.2 ENST00000355384.2 ENST00000397746.3 ENST00000397743.1 |
FTCD
|
formimidoyltransferase cyclodeaminase |
| chr16_-_20587599 | 9.62 |
ENST00000566384.1
ENST00000565232.1 ENST00000567001.1 ENST00000565322.1 ENST00000569344.1 ENST00000329697.6 ENST00000414188.2 ENST00000568882.1 |
ACSM2B
|
acyl-CoA synthetase medium-chain family member 2B |
| chr10_+_101542462 | 9.56 |
ENST00000370449.4
ENST00000370434.1 |
ABCC2
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| chr8_-_95220775 | 9.41 |
ENST00000441892.2
ENST00000521491.1 ENST00000027335.3 |
CDH17
|
cadherin 17, LI cadherin (liver-intestine) |
| chr8_+_21911054 | 8.93 |
ENST00000519850.1
ENST00000381470.3 |
DMTN
|
dematin actin binding protein |
| chr6_+_7541845 | 8.85 |
ENST00000418664.2
|
DSP
|
desmoplakin |
| chr12_-_91546926 | 8.77 |
ENST00000550758.1
|
DCN
|
decorin |
| chr10_-_52645379 | 8.77 |
ENST00000395489.2
|
A1CF
|
APOBEC1 complementation factor |
| chr17_-_202579 | 8.48 |
ENST00000577079.1
ENST00000331302.7 ENST00000536489.2 |
RPH3AL
|
rabphilin 3A-like (without C2 domains) |
| chr2_+_234621551 | 8.46 |
ENST00000608381.1
ENST00000373414.3 |
UGT1A1
UGT1A5
|
UDP glucuronosyltransferase 1 family, polypeptide A8 UDP glucuronosyltransferase 1 family, polypeptide A5 |
| chr20_+_42984330 | 8.11 |
ENST00000316673.4
ENST00000609795.1 ENST00000457232.1 ENST00000609262.1 |
HNF4A
|
hepatocyte nuclear factor 4, alpha |
| chr10_-_52645416 | 8.07 |
ENST00000374001.2
ENST00000373997.3 ENST00000373995.3 ENST00000282641.2 ENST00000395495.1 ENST00000414883.1 |
A1CF
|
APOBEC1 complementation factor |
| chr16_+_20775024 | 7.82 |
ENST00000289416.5
|
ACSM3
|
acyl-CoA synthetase medium-chain family member 3 |
| chr10_+_74451883 | 7.45 |
ENST00000373053.3
ENST00000357157.6 |
MCU
|
mitochondrial calcium uniporter |
| chr1_+_119911425 | 7.28 |
ENST00000361035.4
ENST00000325945.3 |
HAO2
|
hydroxyacid oxidase 2 (long chain) |
| chr2_-_228244013 | 7.16 |
ENST00000304568.3
|
TM4SF20
|
transmembrane 4 L six family member 20 |
| chr16_-_66952742 | 7.11 |
ENST00000565235.2
ENST00000568632.1 ENST00000565796.1 |
CDH16
|
cadherin 16, KSP-cadherin |
| chr6_+_126070726 | 6.98 |
ENST00000368364.3
|
HEY2
|
hes-related family bHLH transcription factor with YRPW motif 2 |
| chr4_+_100495864 | 6.97 |
ENST00000265517.5
ENST00000422897.2 |
MTTP
|
microsomal triglyceride transfer protein |
| chr4_-_76944621 | 6.67 |
ENST00000306602.1
|
CXCL10
|
chemokine (C-X-C motif) ligand 10 |
| chr2_+_234526272 | 6.45 |
ENST00000373450.4
|
UGT1A1
|
UDP glucuronosyltransferase 1 family, polypeptide A8 |
| chr17_+_26800296 | 6.29 |
ENST00000444914.3
ENST00000314669.5 |
SLC13A2
|
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 |
| chr1_-_20141763 | 6.20 |
ENST00000375121.2
|
RNF186
|
ring finger protein 186 |
| chr6_+_25754927 | 6.14 |
ENST00000377905.4
ENST00000439485.2 |
SLC17A4
|
solute carrier family 17, member 4 |
| chr22_-_30968813 | 5.95 |
ENST00000443111.2
ENST00000443136.1 ENST00000426220.1 |
GAL3ST1
|
galactose-3-O-sulfotransferase 1 |
| chr1_+_63063152 | 5.89 |
ENST00000371129.3
|
ANGPTL3
|
angiopoietin-like 3 |
| chr9_+_82186682 | 5.62 |
ENST00000376552.2
|
TLE4
|
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) |
| chr12_-_102874416 | 5.61 |
ENST00000392904.1
ENST00000337514.6 |
IGF1
|
insulin-like growth factor 1 (somatomedin C) |
| chr6_-_25874440 | 5.58 |
ENST00000361703.6
ENST00000397060.4 |
SLC17A3
|
solute carrier family 17 (organic anion transporter), member 3 |
| chr16_+_89696692 | 5.55 |
ENST00000261615.4
|
DPEP1
|
dipeptidase 1 (renal) |
| chr17_+_26800648 | 5.53 |
ENST00000545060.1
|
SLC13A2
|
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 |
| chr6_+_131571535 | 5.39 |
ENST00000474850.2
|
AKAP7
|
A kinase (PRKA) anchor protein 7 |
| chr2_+_27719697 | 5.38 |
ENST00000264717.2
ENST00000424318.2 |
GCKR
|
glucokinase (hexokinase 4) regulator |
| chr15_+_48498480 | 5.34 |
ENST00000380993.3
ENST00000396577.3 |
SLC12A1
|
solute carrier family 12 (sodium/potassium/chloride transporter), member 1 |
| chr16_-_66952779 | 5.32 |
ENST00000570262.1
ENST00000394055.3 ENST00000299752.4 |
CDH16
|
cadherin 16, KSP-cadherin |
| chr11_+_560956 | 5.28 |
ENST00000397582.3
ENST00000344375.4 ENST00000397583.3 |
RASSF7
|
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 |
| chr6_+_31707725 | 5.26 |
ENST00000375755.3
ENST00000375742.3 ENST00000375750.3 ENST00000425703.1 ENST00000534153.4 ENST00000375703.3 ENST00000375740.3 |
MSH5
|
mutS homolog 5 |
| chr22_-_22337154 | 5.17 |
ENST00000413067.2
ENST00000437929.1 ENST00000456075.1 ENST00000434517.1 ENST00000424393.1 ENST00000449704.1 ENST00000437103.1 |
TOP3B
|
topoisomerase (DNA) III beta |
| chr3_-_137893721 | 5.15 |
ENST00000505015.2
ENST00000260803.4 |
DBR1
|
debranching RNA lariats 1 |
| chr4_-_1166954 | 5.06 |
ENST00000514490.1
ENST00000431380.1 ENST00000503765.1 |
SPON2
|
spondin 2, extracellular matrix protein |
| chr5_+_175976324 | 4.98 |
ENST00000261944.5
|
CDHR2
|
cadherin-related family member 2 |
| chr13_-_103719196 | 4.97 |
ENST00000245312.3
|
SLC10A2
|
solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
| chr17_+_26800756 | 4.97 |
ENST00000537681.1
|
SLC13A2
|
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 |
| chr8_-_87755878 | 4.95 |
ENST00000320005.5
|
CNGB3
|
cyclic nucleotide gated channel beta 3 |
| chr14_-_65409438 | 4.91 |
ENST00000557049.1
|
GPX2
|
glutathione peroxidase 2 (gastrointestinal) |
| chr12_+_70132632 | 4.83 |
ENST00000378815.6
ENST00000483530.2 ENST00000325555.9 |
RAB3IP
|
RAB3A interacting protein |
| chr1_+_57320437 | 4.79 |
ENST00000361249.3
|
C8A
|
complement component 8, alpha polypeptide |
| chr16_+_20775358 | 4.70 |
ENST00000440284.2
|
ACSM3
|
acyl-CoA synthetase medium-chain family member 3 |
| chr7_+_130126012 | 4.69 |
ENST00000341441.5
|
MEST
|
mesoderm specific transcript |
| chr20_-_7921090 | 4.63 |
ENST00000378789.3
|
HAO1
|
hydroxyacid oxidase (glycolate oxidase) 1 |
| chr1_+_104293028 | 4.61 |
ENST00000370079.3
|
AMY1C
|
amylase, alpha 1C (salivary) |
| chr12_-_102874378 | 4.52 |
ENST00000456098.1
|
IGF1
|
insulin-like growth factor 1 (somatomedin C) |
| chr7_-_27219849 | 4.50 |
ENST00000396344.4
|
HOXA10
|
homeobox A10 |
| chr21_+_39628655 | 4.49 |
ENST00000398925.1
ENST00000398928.1 ENST00000328656.4 ENST00000443341.1 |
KCNJ15
|
potassium inwardly-rectifying channel, subfamily J, member 15 |
| chr12_-_102874330 | 4.42 |
ENST00000307046.8
|
IGF1
|
insulin-like growth factor 1 (somatomedin C) |
| chr22_-_22337204 | 4.39 |
ENST00000430142.1
ENST00000357179.5 |
TOP3B
|
topoisomerase (DNA) III beta |
| chr21_+_39628852 | 4.31 |
ENST00000398938.2
|
KCNJ15
|
potassium inwardly-rectifying channel, subfamily J, member 15 |
| chr12_+_100897130 | 4.30 |
ENST00000551379.1
ENST00000188403.7 ENST00000551184.1 |
NR1H4
|
nuclear receptor subfamily 1, group H, member 4 |
| chr8_-_124749609 | 4.28 |
ENST00000262219.6
ENST00000419625.1 |
ANXA13
|
annexin A13 |
| chr7_+_141695633 | 4.13 |
ENST00000549489.2
|
MGAM
|
maltase-glucoamylase (alpha-glucosidase) |
| chr13_+_96085847 | 3.91 |
ENST00000376873.3
|
CLDN10
|
claudin 10 |
| chr7_-_150020578 | 3.82 |
ENST00000478393.1
|
ACTR3C
|
ARP3 actin-related protein 3 homolog C (yeast) |
| chr22_+_31002779 | 3.81 |
ENST00000215838.3
|
TCN2
|
transcobalamin II |
| chr7_+_130126165 | 3.75 |
ENST00000427521.1
ENST00000416162.2 ENST00000378576.4 |
MEST
|
mesoderm specific transcript |
| chr6_-_127840453 | 3.70 |
ENST00000556132.1
|
SOGA3
|
SOGA family member 3 |
| chr22_+_31003190 | 3.68 |
ENST00000407817.3
|
TCN2
|
transcobalamin II |
| chr22_+_45098067 | 3.64 |
ENST00000336985.6
ENST00000403696.1 ENST00000457960.1 ENST00000361473.5 |
PRR5
PRR5-ARHGAP8
|
proline rich 5 (renal) PRR5-ARHGAP8 readthrough |
| chr12_+_100867694 | 3.64 |
ENST00000392986.3
ENST00000549996.1 |
NR1H4
|
nuclear receptor subfamily 1, group H, member 4 |
| chr14_-_65409502 | 3.62 |
ENST00000389614.5
|
GPX2
|
glutathione peroxidase 2 (gastrointestinal) |
| chr9_+_102861515 | 3.60 |
ENST00000262457.2
ENST00000541287.1 ENST00000262456.2 ENST00000374921.3 |
INVS
|
inversin |
| chr2_-_162931052 | 3.60 |
ENST00000360534.3
|
DPP4
|
dipeptidyl-peptidase 4 |
| chr6_-_29013017 | 3.55 |
ENST00000377175.1
|
OR2W1
|
olfactory receptor, family 2, subfamily W, member 1 |
| chr4_-_69536346 | 3.49 |
ENST00000338206.5
|
UGT2B15
|
UDP glucuronosyltransferase 2 family, polypeptide B15 |
| chr7_+_141695671 | 3.46 |
ENST00000497673.1
ENST00000475668.2 |
MGAM
|
maltase-glucoamylase (alpha-glucosidase) |
| chr22_+_31003133 | 3.45 |
ENST00000405742.3
|
TCN2
|
transcobalamin II |
| chr19_-_42133420 | 3.38 |
ENST00000221954.2
ENST00000600925.1 |
CEACAM4
|
carcinoembryonic antigen-related cell adhesion molecule 4 |
| chrX_+_16668278 | 3.26 |
ENST00000380200.3
|
S100G
|
S100 calcium binding protein G |
| chr12_+_21284118 | 3.20 |
ENST00000256958.2
|
SLCO1B1
|
solute carrier organic anion transporter family, member 1B1 |
| chr6_+_167704838 | 3.12 |
ENST00000366829.2
|
UNC93A
|
unc-93 homolog A (C. elegans) |
| chr12_-_102874102 | 3.08 |
ENST00000392905.2
|
IGF1
|
insulin-like growth factor 1 (somatomedin C) |
| chr6_+_106534192 | 2.91 |
ENST00000369091.2
ENST00000369096.4 |
PRDM1
|
PR domain containing 1, with ZNF domain |
| chr7_+_120629653 | 2.77 |
ENST00000450913.2
ENST00000340646.5 |
CPED1
|
cadherin-like and PC-esterase domain containing 1 |
| chr17_+_68071458 | 2.73 |
ENST00000589377.1
|
KCNJ16
|
potassium inwardly-rectifying channel, subfamily J, member 16 |
| chr14_+_24590560 | 2.72 |
ENST00000558325.1
|
RP11-468E2.6
|
RP11-468E2.6 |
| chr12_+_100867486 | 2.71 |
ENST00000548884.1
|
NR1H4
|
nuclear receptor subfamily 1, group H, member 4 |
| chr16_-_87970122 | 2.67 |
ENST00000309893.2
|
CA5A
|
carbonic anhydrase VA, mitochondrial |
| chr10_-_72648541 | 2.58 |
ENST00000299299.3
|
PCBD1
|
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| chr1_+_207262170 | 2.47 |
ENST00000367078.3
|
C4BPB
|
complement component 4 binding protein, beta |
| chr12_-_18243075 | 2.45 |
ENST00000536890.1
|
RERGL
|
RERG/RAS-like |
| chr4_-_69434245 | 2.40 |
ENST00000317746.2
|
UGT2B17
|
UDP glucuronosyltransferase 2 family, polypeptide B17 |
| chr17_+_68071389 | 2.36 |
ENST00000283936.1
ENST00000392671.1 |
KCNJ16
|
potassium inwardly-rectifying channel, subfamily J, member 16 |
| chr12_-_18243119 | 2.15 |
ENST00000538724.1
ENST00000229002.2 |
RERGL
|
RERG/RAS-like |
| chr5_-_35195338 | 2.13 |
ENST00000509839.1
|
PRLR
|
prolactin receptor |
| chr20_+_35973080 | 2.10 |
ENST00000445403.1
|
SRC
|
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog |
| chr11_-_128894053 | 2.00 |
ENST00000392657.3
|
ARHGAP32
|
Rho GTPase activating protein 32 |
| chr6_+_167704798 | 1.94 |
ENST00000230256.3
|
UNC93A
|
unc-93 homolog A (C. elegans) |
| chr6_-_117747015 | 1.91 |
ENST00000368508.3
ENST00000368507.3 |
ROS1
|
c-ros oncogene 1 , receptor tyrosine kinase |
| chr1_+_104159999 | 1.91 |
ENST00000414303.2
ENST00000423678.1 |
AMY2A
|
amylase, alpha 2A (pancreatic) |
| chr2_-_47572105 | 1.86 |
ENST00000419035.1
ENST00000448713.1 ENST00000450550.1 ENST00000413185.2 |
AC073283.4
|
AC073283.4 |
| chr13_+_27825706 | 1.85 |
ENST00000272274.4
ENST00000319826.4 ENST00000326092.4 |
RPL21
|
ribosomal protein L21 |
| chr1_+_36789335 | 1.81 |
ENST00000373137.2
|
RP11-268J15.5
|
RP11-268J15.5 |
| chr1_+_207262881 | 1.74 |
ENST00000451804.2
|
C4BPB
|
complement component 4 binding protein, beta |
| chr15_+_58430368 | 1.70 |
ENST00000558772.1
ENST00000219919.4 |
AQP9
|
aquaporin 9 |
| chr4_+_169013666 | 1.64 |
ENST00000359299.3
|
ANXA10
|
annexin A10 |
| chr4_-_70518941 | 1.63 |
ENST00000286604.4
ENST00000505512.1 ENST00000514019.1 |
UGT2A1
UGT2A1
|
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus |
| chr20_+_43029911 | 1.60 |
ENST00000443598.2
ENST00000316099.4 ENST00000415691.2 |
HNF4A
|
hepatocyte nuclear factor 4, alpha |
| chr6_-_29343068 | 1.60 |
ENST00000396806.3
|
OR12D3
|
olfactory receptor, family 12, subfamily D, member 3 |
| chr16_-_420514 | 1.57 |
ENST00000199706.8
|
MRPL28
|
mitochondrial ribosomal protein L28 |
| chr1_+_205197304 | 1.51 |
ENST00000358024.3
|
TMCC2
|
transmembrane and coiled-coil domain family 2 |
| chrX_+_1710484 | 1.49 |
ENST00000313871.3
ENST00000381261.3 |
AKAP17A
|
A kinase (PRKA) anchor protein 17A |
| chr16_-_420338 | 1.48 |
ENST00000450882.1
ENST00000441883.1 ENST00000447696.1 ENST00000389675.2 |
MRPL28
|
mitochondrial ribosomal protein L28 |
| chr1_+_207262627 | 1.36 |
ENST00000391923.1
|
C4BPB
|
complement component 4 binding protein, beta |
| chr3_-_169587621 | 1.34 |
ENST00000523069.1
ENST00000316428.5 ENST00000264676.5 |
LRRC31
|
leucine rich repeat containing 31 |
| chr1_-_159684371 | 1.33 |
ENST00000255030.5
ENST00000437342.1 ENST00000368112.1 ENST00000368111.1 ENST00000368110.1 ENST00000343919.2 |
CRP
|
C-reactive protein, pentraxin-related |
| chr10_-_38146510 | 1.30 |
ENST00000395867.3
|
ZNF248
|
zinc finger protein 248 |
| chr1_-_207206092 | 1.27 |
ENST00000359470.5
ENST00000461135.2 |
C1orf116
|
chromosome 1 open reading frame 116 |
| chr3_+_38307293 | 1.26 |
ENST00000311856.4
|
SLC22A13
|
solute carrier family 22 (organic anion/urate transporter), member 13 |
| chr3_-_192445289 | 1.16 |
ENST00000430714.1
ENST00000418610.1 ENST00000448795.1 ENST00000445105.2 |
FGF12
|
fibroblast growth factor 12 |
| chr4_-_987217 | 1.06 |
ENST00000361661.2
ENST00000398516.2 |
SLC26A1
|
solute carrier family 26 (anion exchanger), member 1 |
| chr12_-_8693539 | 0.94 |
ENST00000299663.3
|
CLEC4E
|
C-type lectin domain family 4, member E |
| chr4_+_187187098 | 0.90 |
ENST00000403665.2
ENST00000264692.4 |
F11
|
coagulation factor XI |
| chr19_-_11639931 | 0.89 |
ENST00000592312.1
ENST00000590480.1 ENST00000585318.1 ENST00000252440.7 ENST00000417981.2 ENST00000270517.7 |
ECSIT
|
ECSIT signalling integrator |
| chr10_-_101690650 | 0.83 |
ENST00000543621.1
|
DNMBP
|
dynamin binding protein |
| chr12_+_20963647 | 0.83 |
ENST00000381545.3
|
SLCO1B3
|
solute carrier organic anion transporter family, member 1B3 |
| chrX_+_120181457 | 0.78 |
ENST00000328078.1
|
GLUD2
|
glutamate dehydrogenase 2 |
| chr7_-_122840015 | 0.77 |
ENST00000194130.2
|
SLC13A1
|
solute carrier family 13 (sodium/sulfate symporter), member 1 |
| chr21_-_19775973 | 0.76 |
ENST00000284885.3
|
TMPRSS15
|
transmembrane protease, serine 15 |
| chr12_+_60058458 | 0.69 |
ENST00000548610.1
|
SLC16A7
|
solute carrier family 16 (monocarboxylate transporter), member 7 |
| chr12_+_20963632 | 0.69 |
ENST00000540853.1
ENST00000261196.2 |
SLCO1B3
|
solute carrier organic anion transporter family, member 1B3 |
| chr22_+_32439019 | 0.63 |
ENST00000266088.4
|
SLC5A1
|
solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| chr11_+_1860200 | 0.62 |
ENST00000381911.1
|
TNNI2
|
troponin I type 2 (skeletal, fast) |
| chr11_-_83393457 | 0.61 |
ENST00000404783.3
|
DLG2
|
discs, large homolog 2 (Drosophila) |
Network of associatons between targets according to the STRING database.
First level regulatory network of HNF1A_HNF1B
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 13.4 | 67.1 | GO:0070980 | biphenyl catabolic process(GO:0070980) |
| 12.3 | 37.0 | GO:2000048 | interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 11.8 | 117.6 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 10.6 | 10.6 | GO:0006789 | bilirubin conjugation(GO:0006789) |
| 10.5 | 31.4 | GO:0019836 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
| 9.9 | 29.6 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
| 9.8 | 98.1 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
| 8.9 | 26.8 | GO:0052314 | serotonin biosynthetic process(GO:0042427) phytoalexin metabolic process(GO:0052314) |
| 7.7 | 38.4 | GO:1903412 | response to bile acid(GO:1903412) |
| 7.4 | 22.2 | GO:0016095 | polyprenol catabolic process(GO:0016095) |
| 7.3 | 51.2 | GO:0008218 | bioluminescence(GO:0008218) |
| 6.2 | 37.3 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 5.8 | 40.9 | GO:0002414 | immunoglobulin transcytosis in epithelial cells(GO:0002414) |
| 5.0 | 15.1 | GO:0016999 | antibiotic metabolic process(GO:0016999) |
| 4.4 | 31.0 | GO:0052696 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 3.6 | 50.9 | GO:0046415 | urate metabolic process(GO:0046415) |
| 3.6 | 10.7 | GO:0090294 | nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250) |
| 3.5 | 17.6 | GO:1904073 | trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) |
| 3.2 | 9.6 | GO:0019557 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
| 3.1 | 45.8 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 3.0 | 27.4 | GO:0045959 | regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027) |
| 3.0 | 15.0 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 2.8 | 16.8 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 2.8 | 13.9 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 2.4 | 21.5 | GO:0019375 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 2.4 | 9.4 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 2.3 | 46.7 | GO:0034374 | low-density lipoprotein particle remodeling(GO:0034374) |
| 2.3 | 7.0 | GO:0010621 | negative regulation of transcription by transcription factor localization(GO:0010621) |
| 2.2 | 15.6 | GO:0055091 | phospholipid homeostasis(GO:0055091) |
| 2.1 | 23.2 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 2.0 | 12.1 | GO:0010193 | response to ozone(GO:0010193) |
| 2.0 | 10.0 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) |
| 1.9 | 19.5 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 1.9 | 89.7 | GO:0051180 | vitamin transport(GO:0051180) |
| 1.9 | 7.6 | GO:0000023 | maltose metabolic process(GO:0000023) |
| 1.9 | 35.3 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 1.8 | 8.9 | GO:1901731 | positive regulation of platelet aggregation(GO:1901731) |
| 1.7 | 5.0 | GO:0090675 | intermicrovillar adhesion(GO:0090675) |
| 1.5 | 4.6 | GO:0009441 | glycolate metabolic process(GO:0009441) |
| 1.3 | 6.7 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
| 1.3 | 8.8 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 1.2 | 7.5 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 1.2 | 11.8 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 1.1 | 13.4 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 1.1 | 34.1 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.9 | 9.9 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.9 | 3.6 | GO:0036343 | psychomotor behavior(GO:0036343) |
| 0.9 | 9.8 | GO:0036112 | medium-chain fatty-acyl-CoA metabolic process(GO:0036112) |
| 0.9 | 7.0 | GO:0034197 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.8 | 12.7 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 0.7 | 13.2 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
| 0.6 | 6.2 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.6 | 5.3 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.6 | 2.9 | GO:0033078 | extrathymic T cell differentiation(GO:0033078) |
| 0.6 | 2.3 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.6 | 9.6 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.5 | 38.5 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.5 | 2.1 | GO:0071393 | cellular response to progesterone stimulus(GO:0071393) |
| 0.5 | 1.9 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
| 0.4 | 12.9 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.4 | 0.8 | GO:0006537 | glutamate biosynthetic process(GO:0006537) |
| 0.4 | 11.1 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.4 | 2.1 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 0.3 | 10.9 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.3 | 3.6 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.3 | 0.9 | GO:0051919 | positive regulation of fibrinolysis(GO:0051919) |
| 0.3 | 2.6 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.3 | 38.5 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.3 | 5.0 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.3 | 1.8 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
| 0.2 | 12.5 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 0.2 | 37.6 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.2 | 7.0 | GO:1901685 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.2 | 4.5 | GO:0060065 | uterus development(GO:0060065) |
| 0.2 | 0.7 | GO:0006848 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.2 | 8.5 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
| 0.2 | 14.5 | GO:0006835 | dicarboxylic acid transport(GO:0006835) |
| 0.1 | 5.4 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.1 | 3.9 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 0.7 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.1 | 5.6 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.1 | 8.5 | GO:0098869 | cellular oxidant detoxification(GO:0098869) |
| 0.1 | 9.6 | GO:0035383 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
| 0.1 | 0.6 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) |
| 0.1 | 5.1 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 0.1 | 7.3 | GO:0009062 | fatty acid catabolic process(GO:0009062) |
| 0.1 | 3.4 | GO:0006909 | phagocytosis(GO:0006909) |
| 0.1 | 2.7 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.0 | 5.3 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 0.4 | GO:0098908 | regulation of neuronal action potential(GO:0098908) |
| 0.0 | 22.9 | GO:0006979 | response to oxidative stress(GO:0006979) |
| 0.0 | 2.2 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.0 | 1.1 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.0 | 2.0 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.0 | 6.7 | GO:0007498 | mesoderm development(GO:0007498) |
| 0.0 | 5.3 | GO:0070507 | regulation of microtubule cytoskeleton organization(GO:0070507) |
| 0.0 | 1.5 | GO:0042982 | amyloid precursor protein metabolic process(GO:0042982) |
| 0.0 | 7.2 | GO:0045861 | negative regulation of proteolysis(GO:0045861) |
| 0.0 | 3.6 | GO:0090090 | negative regulation of canonical Wnt signaling pathway(GO:0090090) |
| 0.0 | 1.0 | GO:0051341 | regulation of oxidoreductase activity(GO:0051341) |
| 0.0 | 0.0 | GO:0002276 | basophil activation involved in immune response(GO:0002276) |
| 0.0 | 0.9 | GO:0002292 | T cell differentiation involved in immune response(GO:0002292) |
| 0.0 | 1.8 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 1.1 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.0 | 0.6 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
| 0.0 | 0.8 | GO:0006898 | receptor-mediated endocytosis(GO:0006898) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 11.3 | 146.6 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 6.2 | 37.0 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 5.6 | 16.8 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 5.0 | 15.0 | GO:0036030 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 3.8 | 34.4 | GO:0005579 | membrane attack complex(GO:0005579) |
| 3.5 | 67.1 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 3.3 | 56.3 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 2.5 | 17.6 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 2.4 | 19.5 | GO:0045179 | apical cortex(GO:0045179) |
| 2.3 | 13.9 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 1.9 | 13.2 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 1.9 | 13.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 1.9 | 7.5 | GO:1990246 | uniplex complex(GO:1990246) |
| 1.7 | 23.2 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 1.1 | 9.6 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 1.0 | 5.0 | GO:0044214 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 1.0 | 26.7 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.8 | 20.0 | GO:0034358 | plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777) |
| 0.7 | 159.2 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.6 | 12.7 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.6 | 8.8 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.5 | 175.2 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.5 | 8.9 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.3 | 5.3 | GO:0032300 | mismatch repair complex(GO:0032300) |
| 0.3 | 7.0 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.3 | 5.5 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.3 | 10.7 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.3 | 16.1 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.2 | 11.9 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.2 | 3.6 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.2 | 7.7 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.2 | 73.7 | GO:0030133 | transport vesicle(GO:0030133) |
| 0.2 | 26.2 | GO:0031227 | intrinsic component of endoplasmic reticulum membrane(GO:0031227) |
| 0.1 | 31.7 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 2.2 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.1 | 7.6 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.1 | 10.9 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 32.3 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 21.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 2.1 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.1 | 81.3 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 32.7 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.1 | 4.9 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.5 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.0 | 64.3 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 5.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 28.7 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 3.1 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.0 | 0.6 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 5.1 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.0 | 1.8 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 3.6 | GO:0005819 | spindle(GO:0005819) |
| 0.0 | 1.9 | GO:0009986 | cell surface(GO:0009986) |
| 0.0 | 2.9 | GO:0005576 | extracellular region(GO:0005576) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 11.3 | 56.3 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 10.2 | 40.9 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 9.9 | 59.5 | GO:0005499 | vitamin D binding(GO:0005499) |
| 9.3 | 37.3 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 5.6 | 22.5 | GO:0008431 | vitamin E binding(GO:0008431) |
| 5.6 | 16.8 | GO:0015361 | low-affinity sodium:dicarboxylate symporter activity(GO:0015361) |
| 5.6 | 22.2 | GO:0047718 | enone reductase activity(GO:0035671) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718) |
| 4.6 | 37.0 | GO:1990405 | protein antigen binding(GO:1990405) |
| 4.0 | 11.9 | GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899) |
| 3.8 | 38.4 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 3.6 | 32.0 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 3.6 | 10.7 | GO:0038181 | bile acid receptor activity(GO:0038181) chenodeoxycholic acid binding(GO:1902122) |
| 3.5 | 14.1 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 3.4 | 34.1 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 3.4 | 40.8 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
| 3.2 | 129.6 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 3.1 | 21.5 | GO:0050694 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 2.9 | 25.8 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 2.8 | 19.5 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 2.4 | 9.6 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
| 2.4 | 9.5 | GO:0016160 | amylase activity(GO:0016160) |
| 2.4 | 9.4 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
| 2.3 | 46.7 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 2.3 | 13.9 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 2.0 | 11.8 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 2.0 | 31.4 | GO:0015643 | toxic substance binding(GO:0015643) |
| 1.7 | 7.0 | GO:0035939 | microsatellite binding(GO:0035939) |
| 1.7 | 10.0 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 1.6 | 9.6 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 1.3 | 6.7 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 1.2 | 5.0 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 1.2 | 128.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 1.2 | 9.6 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 1.2 | 11.9 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 1.1 | 25.5 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 1.1 | 5.4 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 1.0 | 10.9 | GO:0031419 | cobalamin binding(GO:0031419) |
| 1.0 | 8.8 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.8 | 12.7 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.8 | 5.5 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.8 | 13.9 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.8 | 8.5 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.7 | 76.4 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.7 | 4.9 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.7 | 29.6 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.6 | 2.6 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
| 0.6 | 12.1 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.6 | 33.7 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.6 | 2.3 | GO:0015265 | glycerol channel activity(GO:0015254) urea channel activity(GO:0015265) |
| 0.5 | 16.1 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.5 | 26.8 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.4 | 2.1 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 0.4 | 5.3 | GO:0015377 | cation:chloride symporter activity(GO:0015377) |
| 0.4 | 9.9 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.4 | 37.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.3 | 23.2 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.3 | 8.5 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.3 | 1.3 | GO:0033265 | choline binding(GO:0033265) |
| 0.3 | 5.3 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 0.3 | 2.1 | GO:0071253 | connexin binding(GO:0071253) |
| 0.2 | 5.9 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
| 0.2 | 9.7 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.2 | 1.8 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.2 | 5.4 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.2 | 7.0 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.2 | 0.8 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.2 | 8.9 | GO:0043621 | protein self-association(GO:0043621) |
| 0.2 | 5.1 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.2 | 3.6 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.2 | 5.1 | GO:0016891 | endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) |
| 0.2 | 0.7 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.2 | 8.3 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.2 | 16.8 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.2 | 2.7 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.1 | 4.8 | GO:0001848 | complement binding(GO:0001848) |
| 0.1 | 5.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 33.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 7.0 | GO:0005548 | phospholipid transporter activity(GO:0005548) |
| 0.1 | 5.6 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 26.1 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.1 | 2.9 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 1.1 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.6 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.0 | 1.5 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 4.5 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 8.2 | GO:0016787 | hydrolase activity(GO:0016787) |
| 0.0 | 1.2 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 1.9 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.0 | 2.0 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 0.3 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 0.0 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
| 0.0 | 1.4 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 2.0 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 151.7 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 1.9 | 147.0 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.7 | 175.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.4 | 21.2 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.4 | 23.2 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.4 | 17.6 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.4 | 8.8 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.3 | 28.4 | PID FGF PATHWAY | FGF signaling pathway |
| 0.3 | 10.0 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.3 | 13.2 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.2 | 10.7 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.2 | 4.9 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.2 | 5.1 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.2 | 12.2 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.2 | 6.7 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.1 | 4.5 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 7.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 8.8 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 8.5 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 6.2 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 20.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 5.9 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.1 | 3.6 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 6.9 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 1.3 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 2.1 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 2.0 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 2.0 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 8.5 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.0 | 0.8 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 2.9 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.5 | 119.9 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 4.3 | 112.7 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 2.8 | 71.1 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 2.7 | 38.4 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 2.6 | 41.1 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 2.3 | 61.1 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 1.6 | 35.7 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 1.5 | 33.7 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 1.5 | 56.3 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 1.5 | 11.8 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 1.2 | 20.0 | REACTOME LIPOPROTEIN METABOLISM | Genes involved in Lipoprotein metabolism |
| 1.2 | 25.8 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 1.2 | 18.2 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 1.2 | 12.8 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 1.2 | 26.8 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.9 | 23.2 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.7 | 12.1 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.5 | 21.5 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.5 | 13.2 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.5 | 8.8 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.4 | 13.9 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.4 | 51.2 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.4 | 19.5 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.3 | 11.9 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.3 | 9.7 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.3 | 9.6 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.3 | 3.6 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.2 | 12.7 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.2 | 9.6 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.2 | 2.7 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.2 | 2.3 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.2 | 9.0 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.2 | 2.1 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.1 | 19.5 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.1 | 2.1 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.1 | 6.7 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 3.9 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 16.8 | REACTOME MRNA PROCESSING | Genes involved in mRNA Processing |
| 0.1 | 0.9 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.1 | 3.5 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.1 | 5.3 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.1 | 14.5 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.1 | 6.4 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 3.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 1.8 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |