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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXA13

Z-value: 0.62

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Transcription factors associated with HOXA13

Gene Symbol Gene ID Gene Info
HOXA13
ENSG00000106031.6 homeobox A13

Activity profile of HOXA13 motif

Sorted Z-values of HOXA13 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_189839046 13.82 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr12_-_91539918 12.96 ENST00000548218.1
DCN
decorin
chr6_+_121756809 11.91 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr3_-_123339418 10.06 ENST00000583087.1
MYLK
myosin light chain kinase
chr3_-_123339343 9.60 ENST00000578202.1
MYLK
myosin light chain kinase
chr12_-_91546926 8.10 ENST00000550758.1
DCN
decorin
chr3_-_112127981 6.93 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr5_-_79287060 6.81 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
MTX3
metaxin 3
chr12_+_6309517 6.46 ENST00000382519.4
ENST00000009180.4
CD9
CD9 molecule
chr1_+_43766642 6.07 ENST00000372476.3
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr12_+_120105558 5.67 ENST00000229328.5
ENST00000541640.1
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr8_+_133879193 5.58 ENST00000377869.1
ENST00000220616.4
TG
thyroglobulin
chr6_+_151042224 5.53 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr12_-_12491608 5.46 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr4_+_106631966 5.16 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
GSTCD
glutathione S-transferase, C-terminal domain containing
chr19_+_16999654 4.63 ENST00000248076.3
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr6_+_19837592 4.48 ENST00000378700.3
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr8_-_86290333 4.33 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1
carbonic anhydrase I
chr12_+_12878829 3.99 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr12_-_71182695 3.95 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr9_+_137979506 3.88 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
OLFM1
olfactomedin 1
chr14_-_92414055 3.83 ENST00000342058.4
FBLN5
fibulin 5
chr18_+_39766626 3.81 ENST00000593234.1
ENST00000585627.1
ENST00000591199.1
ENST00000586990.1
ENST00000593051.1
ENST00000593316.1
ENST00000591381.1
ENST00000585639.1
ENST00000589068.1
LINC00907
long intergenic non-protein coding RNA 907
chr8_-_95274536 3.80 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr6_+_131894284 3.74 ENST00000368087.3
ENST00000356962.2
ARG1
arginase 1
chr11_+_61891445 3.64 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP
inner centromere protein antigens 135/155kDa
chr3_+_101546827 3.56 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr9_+_706842 3.50 ENST00000382293.3
KANK1
KN motif and ankyrin repeat domains 1
chr11_-_114466477 3.41 ENST00000375478.3
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr2_-_177502254 3.21 ENST00000339037.3
AC017048.3
long intergenic non-protein coding RNA 1116
chrX_+_35816459 3.19 ENST00000399988.1
ENST00000399992.1
ENST00000399987.1
ENST00000399989.1
MAGEB16
melanoma antigen family B, 16
chr2_-_32390801 3.04 ENST00000608489.1
RP11-563N4.1
RP11-563N4.1
chr6_-_11807277 3.02 ENST00000379415.2
ADTRP
androgen-dependent TFPI-regulating protein
chr16_+_66914264 3.00 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr3_-_99569821 2.84 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr17_-_40021656 2.83 ENST00000319121.3
KLHL11
kelch-like family member 11
chr1_-_25756638 2.82 ENST00000349320.3
RHCE
Rh blood group, CcEe antigens
chr4_+_70894130 2.75 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr12_-_53074182 2.70 ENST00000252244.3
KRT1
keratin 1
chr20_-_52687059 2.69 ENST00000371435.2
ENST00000395961.3
BCAS1
breast carcinoma amplified sequence 1
chr3_-_114477787 2.66 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr7_+_95401877 2.58 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr4_+_74269956 2.57 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB
albumin
chr11_-_114466471 2.57 ENST00000424261.2
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr7_+_95401851 2.53 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr5_-_138210977 2.50 ENST00000274711.6
ENST00000521094.2
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr12_+_26274917 2.49 ENST00000538142.1
SSPN
sarcospan
chr14_+_29236269 2.41 ENST00000313071.4
FOXG1
forkhead box G1
chr15_-_99789736 2.37 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23
tetratricopeptide repeat domain 23
chr6_+_148663729 2.28 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr1_+_13910194 2.25 ENST00000376057.4
ENST00000510906.1
PDPN
podoplanin
chr12_-_8693539 2.24 ENST00000299663.3
CLEC4E
C-type lectin domain family 4, member E
chr4_-_89978299 2.18 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
FAM13A
family with sequence similarity 13, member A
chr5_-_19988339 2.11 ENST00000382275.1
CDH18
cadherin 18, type 2
chr3_-_160823158 2.04 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr11_-_104480019 2.03 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr7_+_80275752 2.01 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr8_-_9008206 2.00 ENST00000310455.3
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr3_-_149093499 1.99 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr19_+_8483272 1.95 ENST00000602117.1
MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr19_-_44809121 1.95 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
ZNF235
zinc finger protein 235
chr5_+_66254698 1.94 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr9_+_91933726 1.93 ENST00000534113.2
SECISBP2
SECIS binding protein 2
chr11_+_94706804 1.92 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr3_-_126373929 1.91 ENST00000523403.1
ENST00000524230.2
TXNRD3
thioredoxin reductase 3
chr7_+_80275621 1.91 ENST00000426978.1
ENST00000432207.1
CD36
CD36 molecule (thrombospondin receptor)
chr10_-_50970322 1.89 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chrX_-_38186775 1.88 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
RPGR
retinitis pigmentosa GTPase regulator
chr19_+_16830774 1.83 ENST00000524140.2
NWD1
NACHT and WD repeat domain containing 1
chr4_-_17513702 1.81 ENST00000428702.2
ENST00000508623.1
ENST00000513615.1
QDPR
quinoid dihydropteridine reductase
chr3_-_160822858 1.79 ENST00000488170.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr14_-_71609965 1.78 ENST00000602957.1
RP6-91H8.3
RP6-91H8.3
chr3_-_160823040 1.78 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr16_+_82090028 1.78 ENST00000568090.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr1_-_31845914 1.76 ENST00000373713.2
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr18_-_5544241 1.76 ENST00000341928.2
ENST00000540638.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr16_-_21289627 1.76 ENST00000396023.2
ENST00000415987.2
CRYM
crystallin, mu
chr13_-_36429763 1.75 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr11_+_101785727 1.74 ENST00000263468.8
KIAA1377
KIAA1377
chr18_-_52989217 1.73 ENST00000570287.2
TCF4
transcription factor 4
chr11_-_124670550 1.72 ENST00000239614.4
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr1_+_173793777 1.71 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr1_-_216978709 1.69 ENST00000360012.3
ESRRG
estrogen-related receptor gamma
chr17_+_16284104 1.69 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
UBB
ubiquitin B
chr22_+_21400229 1.65 ENST00000342608.4
ENST00000543388.1
ENST00000442047.1
AC002472.13
Leucine-rich repeat-containing protein LOC400891
chr2_-_241737128 1.63 ENST00000404283.3
KIF1A
kinesin family member 1A
chr4_+_70861647 1.61 ENST00000246895.4
ENST00000381060.2
STATH
statherin
chr22_+_39916558 1.56 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr19_-_18632861 1.54 ENST00000262809.4
ELL
elongation factor RNA polymerase II
chr14_+_100485712 1.54 ENST00000544450.2
EVL
Enah/Vasp-like
chr11_-_85565906 1.53 ENST00000544076.1
AP000974.1
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein
chr19_-_47987419 1.52 ENST00000536339.1
ENST00000595554.1
ENST00000600271.1
ENST00000338134.3
KPTN
kaptin (actin binding protein)
chr22_+_18632666 1.52 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr19_+_35773242 1.50 ENST00000222304.3
HAMP
hepcidin antimicrobial peptide
chr3_+_190333097 1.50 ENST00000412080.1
IL1RAP
interleukin 1 receptor accessory protein
chr4_+_95679072 1.47 ENST00000515059.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr4_+_72052964 1.46 ENST00000264485.5
ENST00000425175.1
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr4_-_155533787 1.44 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr19_+_859654 1.43 ENST00000592860.1
CFD
complement factor D (adipsin)
chrX_+_37850026 1.43 ENST00000341016.3
CXorf27
chromosome X open reading frame 27
chr2_+_33359646 1.42 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr7_-_27169801 1.38 ENST00000511914.1
HOXA4
homeobox A4
chr7_+_80275953 1.38 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr2_+_33359687 1.36 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr22_+_38142235 1.34 ENST00000407319.2
ENST00000403663.2
ENST00000428075.1
TRIOBP
TRIO and F-actin binding protein
chr1_+_202431859 1.33 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr16_+_75252878 1.33 ENST00000361017.4
CTRB1
chymotrypsinogen B1
chr11_+_7110165 1.29 ENST00000306904.5
RBMXL2
RNA binding motif protein, X-linked-like 2
chr21_+_39644172 1.29 ENST00000398932.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr17_+_16284399 1.29 ENST00000535788.1
UBB
ubiquitin B
chr11_+_61015594 1.28 ENST00000451616.2
PGA5
pepsinogen 5, group I (pepsinogen A)
chr9_-_21305312 1.27 ENST00000259555.4
IFNA5
interferon, alpha 5
chr16_-_66764119 1.26 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr4_-_17513851 1.25 ENST00000281243.5
QDPR
quinoid dihydropteridine reductase
chr19_+_54369608 1.21 ENST00000336967.3
MYADM
myeloid-associated differentiation marker
chr21_+_39644305 1.20 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr11_-_10590238 1.20 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr11_+_62037622 1.20 ENST00000227918.2
ENST00000525380.1
SCGB2A2
secretoglobin, family 2A, member 2
chr5_+_140535577 1.20 ENST00000539533.1
PCDHB17
Protocadherin-psi1; Uncharacterized protein
chr21_+_39644395 1.20 ENST00000398934.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr3_+_129159039 1.19 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr21_+_39628655 1.16 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr5_-_78808617 1.15 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chr7_-_27224795 1.14 ENST00000006015.3
HOXA11
homeobox A11
chr1_-_46642154 1.13 ENST00000540385.1
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr2_+_182756615 1.13 ENST00000431877.2
ENST00000320370.7
SSFA2
sperm specific antigen 2
chr2_+_33661382 1.11 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_+_78769549 1.10 ENST00000370758.1
PTGFR
prostaglandin F receptor (FP)
chr2_-_86850949 1.09 ENST00000237455.4
RNF103
ring finger protein 103
chr16_-_90096309 1.09 ENST00000408886.2
C16orf3
chromosome 16 open reading frame 3
chr6_+_73076432 1.08 ENST00000414192.2
RIMS1
regulating synaptic membrane exocytosis 1
chr4_+_25657444 1.05 ENST00000504570.1
ENST00000382051.3
SLC34A2
solute carrier family 34 (type II sodium/phosphate contransporter), member 2
chr15_-_88799661 1.05 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr1_+_78511586 1.05 ENST00000370759.3
GIPC2
GIPC PDZ domain containing family, member 2
chr18_-_52989525 1.04 ENST00000457482.3
TCF4
transcription factor 4
chr9_-_98269699 1.04 ENST00000429896.2
PTCH1
patched 1
chr20_+_55204351 1.04 ENST00000201031.2
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr1_-_207224307 1.01 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr1_-_16763911 0.99 ENST00000375577.1
ENST00000335496.1
SPATA21
spermatogenesis associated 21
chr19_+_13858593 0.99 ENST00000221554.8
CCDC130
coiled-coil domain containing 130
chr17_-_39553844 0.99 ENST00000251645.2
KRT31
keratin 31
chr4_+_70796784 0.97 ENST00000246891.4
ENST00000444405.3
CSN1S1
casein alpha s1
chr14_+_50234309 0.96 ENST00000298307.5
KLHDC2
kelch domain containing 2
chr1_-_28177255 0.93 ENST00000601459.1
AL109927.1
HCG2032222; PRO2047; Uncharacterized protein
chr4_+_90823130 0.93 ENST00000508372.1
MMRN1
multimerin 1
chr21_+_39644214 0.93 ENST00000438657.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr14_-_102706934 0.92 ENST00000523231.1
ENST00000524370.1
ENST00000517966.1
MOK
MOK protein kinase
chr5_+_67584174 0.92 ENST00000320694.8
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr19_+_36545833 0.92 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WDR62
WD repeat domain 62
chr1_+_50575292 0.92 ENST00000371821.1
ENST00000371819.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr21_+_39628852 0.91 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr18_-_53255766 0.89 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr1_-_111970353 0.87 ENST00000369732.3
OVGP1
oviductal glycoprotein 1, 120kDa
chr5_-_160973649 0.87 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr15_+_79166065 0.86 ENST00000559690.1
ENST00000559158.1
MORF4L1
mortality factor 4 like 1
chr1_+_196857144 0.84 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4
complement factor H-related 4
chr10_-_52383644 0.83 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chrX_+_49687216 0.82 ENST00000376088.3
CLCN5
chloride channel, voltage-sensitive 5
chr11_+_113779704 0.81 ENST00000537778.1
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
chr3_-_52864680 0.80 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
ITIH4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr19_+_19322758 0.78 ENST00000252575.6
NCAN
neurocan
chr12_-_52828147 0.77 ENST00000252245.5
KRT75
keratin 75
chrX_-_11284095 0.77 ENST00000303025.6
ENST00000534860.1
ARHGAP6
Rho GTPase activating protein 6
chr4_-_110723134 0.75 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr1_-_109940550 0.75 ENST00000256637.6
SORT1
sortilin 1
chr1_+_100818009 0.75 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr17_-_39507064 0.74 ENST00000007735.3
KRT33A
keratin 33A
chr7_-_50633078 0.73 ENST00000444124.2
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr16_+_81348528 0.73 ENST00000568107.2
GAN
gigaxonin
chr15_-_58571445 0.72 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chrX_+_100878079 0.71 ENST00000471229.2
ARMCX3
armadillo repeat containing, X-linked 3
chr3_+_132316081 0.71 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr8_-_63998590 0.71 ENST00000260116.4
TTPA
tocopherol (alpha) transfer protein
chr4_+_128702969 0.71 ENST00000508776.1
ENST00000439123.2
HSPA4L
heat shock 70kDa protein 4-like
chr19_-_6279932 0.71 ENST00000252674.7
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr8_-_16050288 0.70 ENST00000350896.3
MSR1
macrophage scavenger receptor 1
chr12_-_50677255 0.67 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIMA1
LIM domain and actin binding 1
chr17_-_39538550 0.66 ENST00000394001.1
KRT34
keratin 34
chr17_-_56769382 0.65 ENST00000240361.8
ENST00000349033.5
ENST00000389934.3
TEX14
testis expressed 14
chr2_+_192109911 0.64 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
MYO1B
myosin IB
chr17_+_29664830 0.64 ENST00000444181.2
ENST00000417592.2
NF1
neurofibromin 1
chr4_-_170533723 0.64 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
NEK1
NIMA-related kinase 1
chr10_-_51371321 0.63 ENST00000602930.1
AGAP8
ArfGAP with GTPase domain, ankyrin repeat and PH domain 8
chr12_+_121163538 0.63 ENST00000242592.4
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr11_-_10590118 0.62 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr19_+_852291 0.61 ENST00000263621.1
ELANE
elastase, neutrophil expressed
chr2_+_204732487 0.61 ENST00000302823.3
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr6_-_167571817 0.61 ENST00000366834.1
GPR31
G protein-coupled receptor 31
chr5_-_22853429 0.59 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr19_-_48547294 0.58 ENST00000293255.2
CABP5
calcium binding protein 5
chr15_-_55881135 0.58 ENST00000302000.6
PYGO1
pygopus family PHD finger 1
chr22_-_38577731 0.58 ENST00000335539.3
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr22_-_38577782 0.58 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr8_-_16050214 0.57 ENST00000262101.5
MSR1
macrophage scavenger receptor 1
chr11_+_60995849 0.57 ENST00000537932.1
PGA4
pepsinogen 4, group I (pepsinogen A)
chr5_-_138533973 0.55 ENST00000507002.1
ENST00000505830.1
ENST00000508639.1
ENST00000265195.5
SIL1
SIL1 nucleotide exchange factor
chr1_-_173176452 0.54 ENST00000281834.3
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr7_-_151511911 0.53 ENST00000392801.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr9_-_98269481 0.52 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
PTCH1
patched 1
chr1_+_171750776 0.50 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
METTL13
methyltransferase like 13

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 33.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
2.8 11.1 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.8 21.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.3 3.8 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
1.2 3.5 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.0 3.1 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.9 4.5 GO:0061107 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.9 2.6 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.8 5.3 GO:0072564 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.8 2.3 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.7 3.7 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.7 4.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.6 5.6 GO:0015705 iodide transport(GO:0015705)
0.6 1.8 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.6 6.5 GO:0009414 response to water deprivation(GO:0009414)
0.6 4.6 GO:0060155 platelet dense granule organization(GO:0060155)
0.6 3.4 GO:0060613 fat pad development(GO:0060613)
0.6 1.7 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.6 2.3 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.5 1.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.5 1.5 GO:1904479 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.5 5.1 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.4 3.9 GO:0003190 atrioventricular valve formation(GO:0003190)
0.4 4.0 GO:0042118 endothelial cell activation(GO:0042118)
0.4 1.6 GO:0021997 response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.4 1.9 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.4 1.5 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.4 1.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.4 0.7 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.3 1.0 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.3 1.0 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.3 3.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 4.4 GO:0035878 nail development(GO:0035878)
0.3 2.8 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 1.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.3 1.2 GO:0035720 signal transduction downstream of smoothened(GO:0007227) intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.3 1.5 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3 0.9 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.3 1.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.3 1.4 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.3 1.3 GO:0030047 actin modification(GO:0030047)
0.3 5.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.3 1.8 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 1.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 1.9 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 0.6 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.2 2.5 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.2 2.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 0.7 GO:0090212 vitamin E metabolic process(GO:0042360) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.2 1.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 6.1 GO:0045026 plasma membrane fusion(GO:0045026)
0.2 1.8 GO:0006554 lysine catabolic process(GO:0006554)
0.2 1.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 1.6 GO:0046541 saliva secretion(GO:0046541)
0.1 2.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 6.7 GO:0010107 potassium ion import(GO:0010107)
0.1 1.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.1 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 1.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 1.3 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 0.7 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.1 5.8 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.4 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 0.6 GO:1903238 neutrophil mediated killing of gram-negative bacterium(GO:0070945) positive regulation of leukocyte tethering or rolling(GO:1903238)
0.1 2.8 GO:0015695 organic cation transport(GO:0015695)
0.1 0.5 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.7 GO:0035799 ureter maturation(GO:0035799)
0.1 0.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 2.0 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 0.5 GO:0097527 Fas signaling pathway(GO:0036337) necroptotic signaling pathway(GO:0097527)
0.1 1.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 2.7 GO:0050832 defense response to fungus(GO:0050832)
0.1 0.8 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 1.8 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 1.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 1.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 1.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.6 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 0.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 1.9 GO:0000305 response to oxygen radical(GO:0000305)
0.0 1.3 GO:0051642 centrosome localization(GO:0051642)
0.0 1.1 GO:0000165 MAPK cascade(GO:0000165)
0.0 0.9 GO:0071420 cellular response to histamine(GO:0071420)
0.0 1.9 GO:0042073 intraciliary transport(GO:0042073)
0.0 1.1 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 2.7 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.2 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 4.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.4 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.4 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 2.2 GO:0002292 T cell differentiation involved in immune response(GO:0002292)
0.0 0.8 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.6 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 1.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.9 GO:0007099 centriole replication(GO:0007099)
0.0 0.3 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 3.0 GO:0000910 cytokinesis(GO:0000910)
0.0 0.2 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 2.1 GO:0070268 cornification(GO:0070268)
0.0 0.7 GO:0031529 ruffle organization(GO:0031529)
0.0 1.6 GO:0030449 regulation of complement activation(GO:0030449)
0.0 1.0 GO:0009615 response to virus(GO:0009615)
0.0 0.3 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 2.2 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 1.7 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.9 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.4 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 21.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.2 13.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.8 11.9 GO:0005916 fascia adherens(GO:0005916)
0.7 3.6 GO:0000801 central element(GO:0000801)
0.4 3.8 GO:0071953 elastic fiber(GO:0071953)
0.4 11.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 6.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 1.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.3 1.6 GO:1990037 Lewy body core(GO:1990037)
0.3 20.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 5.4 GO:0044295 axonal growth cone(GO:0044295)
0.2 0.9 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 2.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 6.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 2.0 GO:0042587 glycogen granule(GO:0042587)
0.2 1.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 1.5 GO:0045179 apical cortex(GO:0045179)
0.2 1.9 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 2.8 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 4.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 1.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 3.8 GO:0051233 spindle midzone(GO:0051233)
0.1 0.7 GO:0060091 kinocilium(GO:0060091)
0.1 1.8 GO:0033270 paranode region of axon(GO:0033270)
0.1 2.7 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 1.9 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 2.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 2.6 GO:0045095 keratin filament(GO:0045095)
0.1 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.5 GO:0032420 stereocilium(GO:0032420)
0.1 4.5 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 4.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.8 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 2.2 GO:0031672 A band(GO:0031672)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.2 GO:0043034 costamere(GO:0043034)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.6 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 1.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 5.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.0 1.6 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.9 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 2.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 2.0 GO:0030496 midbody(GO:0030496)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0043204 perikaryon(GO:0043204)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 19.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.9 5.6 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
1.9 11.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
1.0 13.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.9 5.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.8 4.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.6 3.1 GO:0070404 NADH binding(GO:0070404)
0.6 1.8 GO:0070538 oleic acid binding(GO:0070538)
0.6 2.8 GO:0050436 microfibril binding(GO:0050436)
0.5 4.3 GO:0004064 arylesterase activity(GO:0004064)
0.5 1.6 GO:0046848 hydroxyapatite binding(GO:0046848)
0.5 3.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 1.8 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.4 6.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.4 1.8 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.4 1.9 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.4 6.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 1.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.3 1.7 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.3 1.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.3 1.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.3 6.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 1.6 GO:0097108 hedgehog family protein binding(GO:0097108)
0.3 21.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 3.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 0.8 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 3.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 1.5 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.2 1.7 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 0.8 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.2 1.9 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.2 2.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 0.7 GO:0008431 vitamin E binding(GO:0008431)
0.2 2.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.2 2.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 1.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 2.6 GO:0015643 toxic substance binding(GO:0015643)
0.2 0.8 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 4.0 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 1.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.9 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 1.3 GO:0045159 myosin II binding(GO:0045159)
0.1 2.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.5 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 1.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 2.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.5 GO:0005522 profilin binding(GO:0005522)
0.1 1.9 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.9 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1 2.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 1.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.8 GO:0005319 lipid transporter activity(GO:0005319)
0.1 0.2 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 6.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 1.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 10.1 GO:0005178 integrin binding(GO:0005178)
0.1 0.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 5.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 3.9 GO:0005179 hormone activity(GO:0005179)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.5 GO:0019902 phosphatase binding(GO:0019902)
0.0 3.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 2.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.4 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 31.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.4 23.3 PID AURORA B PATHWAY Aurora B signaling
0.3 5.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 13.8 NABA COLLAGENS Genes encoding collagen proteins
0.2 6.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 7.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 5.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 3.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 3.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 6.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 1.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID SHP2 PATHWAY SHP2 signaling
0.0 0.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 21.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.7 11.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 6.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 4.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 17.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 13.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 6.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 4.6 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 1.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 18.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 2.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 2.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 3.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.9 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 1.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 3.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.9 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.1 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 2.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 3.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives