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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXB8

Z-value: 1.02

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Transcription factors associated with HOXB8

Gene Symbol Gene ID Gene Info
HOXB8
ENSG00000120068.5 homeobox B8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB8hg19_v2_chr17_-_46692287_46692317,
hg19_v2_chr17_-_46691990_46692066		-0.366.1e-08Click!

Activity profile of HOXB8 motif

Sorted Z-values of HOXB8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_14521379 18.50 ENST00000249923.3
ENST00000529866.1
ENST00000439561.2
ENST00000534771.1
COPB1
coatomer protein complex, subunit beta 1
chr8_+_98788003 17.13 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr6_+_63921399 16.81 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chrX_-_77225135 14.55 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr8_-_27695552 14.40 ENST00000522944.1
ENST00000301905.4
PBK
PDZ binding kinase
chrX_+_119737806 13.90 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr1_+_224544552 13.63 ENST00000465271.1
ENST00000366858.3
CNIH4
cornichon family AMPA receptor auxiliary protein 4
chr1_+_224544572 13.60 ENST00000366857.5
ENST00000366856.3
CNIH4
cornichon family AMPA receptor auxiliary protein 4
chr11_+_101983176 12.93 ENST00000524575.1
YAP1
Yes-associated protein 1
chr1_-_63988846 12.80 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr4_+_83956237 12.76 ENST00000264389.2
COPS4
COP9 signalosome subunit 4
chr5_+_159848854 11.84 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1
pituitary tumor-transforming 1
chr19_+_50180317 11.62 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr19_-_10697895 11.59 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr7_-_87856280 11.40 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chr7_-_87856303 11.10 ENST00000394641.3
SRI
sorcin
chr10_+_62538089 10.89 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chr4_+_108925787 10.51 ENST00000454409.2
HADH
hydroxyacyl-CoA dehydrogenase
chr12_-_54653313 10.39 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr10_+_5488564 10.10 ENST00000449083.1
ENST00000380359.3
NET1
neuroepithelial cell transforming 1
chr6_+_34204642 10.06 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr7_+_107224364 10.04 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr16_+_30064411 10.03 ENST00000338110.5
ALDOA
aldolase A, fructose-bisphosphate
chr3_+_139063372 9.92 ENST00000478464.1
MRPS22
mitochondrial ribosomal protein S22
chr12_+_16109519 9.89 ENST00000526530.1
DERA
deoxyribose-phosphate aldolase (putative)
chr3_-_64009658 9.80 ENST00000394431.2
PSMD6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr1_-_197115818 9.80 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr2_+_192141611 9.80 ENST00000392316.1
MYO1B
myosin IB
chr16_+_84801852 9.77 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr16_+_30064444 9.76 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
ALDOA
aldolase A, fructose-bisphosphate
chrX_-_102943022 9.62 ENST00000433176.2
MORF4L2
mortality factor 4 like 2
chr15_-_72523454 9.53 ENST00000565154.1
ENST00000565184.1
ENST00000389093.3
ENST00000449901.2
ENST00000335181.5
ENST00000319622.6
PKM
pyruvate kinase, muscle
chr6_+_63921351 9.38 ENST00000370659.1
FKBP1C
FK506 binding protein 1C
chr17_-_40288449 9.30 ENST00000552162.1
ENST00000550504.1
RAB5C
RAB5C, member RAS oncogene family
chr6_+_24667257 9.28 ENST00000537591.1
ENST00000230048.4
ACOT13
acyl-CoA thioesterase 13
chrX_+_56590002 9.26 ENST00000338222.5
UBQLN2
ubiquilin 2
chr11_-_47664072 9.22 ENST00000542981.1
ENST00000530428.1
ENST00000302503.3
MTCH2
mitochondrial carrier 2
chr2_-_10587897 9.17 ENST00000405333.1
ENST00000443218.1
ODC1
ornithine decarboxylase 1
chr20_+_34802295 9.17 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr9_-_70465758 9.13 ENST00000489273.1
CBWD5
COBW domain containing 5
chr16_-_46655538 9.13 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr6_+_57037089 9.06 ENST00000370693.5
BAG2
BCL2-associated athanogene 2
chr10_+_62538248 8.95 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chr14_+_56078695 8.88 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chr14_+_78174414 8.81 ENST00000557342.1
ENST00000238688.5
ENST00000557623.1
ENST00000557431.1
ENST00000556831.1
ENST00000556375.1
ENST00000553981.1
SLIRP
SRA stem-loop interacting RNA binding protein
chr3_+_138340049 8.81 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr10_+_94352956 8.77 ENST00000260731.3
KIF11
kinesin family member 11
chr9_-_86593238 8.73 ENST00000351839.3
HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr5_-_10761206 8.73 ENST00000432074.2
ENST00000230895.6
DAP
death-associated protein
chr8_-_81083341 8.69 ENST00000519303.2
TPD52
tumor protein D52
chr16_+_15489603 8.57 ENST00000568766.1
ENST00000287594.7
RP11-1021N1.1
MPV17L
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chrX_+_114827818 8.53 ENST00000420625.2
PLS3
plastin 3
chr17_+_8191815 8.41 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr19_+_52932435 8.33 ENST00000301085.4
ZNF534
zinc finger protein 534
chr12_+_96252706 8.31 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr11_-_63376013 8.26 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr2_+_102456277 8.15 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_+_27886330 8.15 ENST00000326019.6
SLC4A1AP
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr12_-_54652060 8.09 ENST00000552562.1
CBX5
chromobox homolog 5
chr6_-_24667232 8.06 ENST00000378198.4
TDP2
tyrosyl-DNA phosphodiesterase 2
chr1_-_246357029 8.05 ENST00000391836.2
SMYD3
SET and MYND domain containing 3
chr2_-_151344172 8.05 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr15_-_55489097 8.03 ENST00000260443.4
RSL24D1
ribosomal L24 domain containing 1
chr2_-_152146385 8.03 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr11_+_844406 8.02 ENST00000397404.1
TSPAN4
tetraspanin 4
chr4_+_69681710 8.02 ENST00000265403.7
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B10
chr3_+_87276407 7.99 ENST00000471660.1
ENST00000263780.4
ENST00000494980.1
CHMP2B
charged multivesicular body protein 2B
chr11_+_2405833 7.99 ENST00000527343.1
ENST00000464784.2
CD81
CD81 molecule
chr2_+_219110149 7.99 ENST00000456575.1
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr2_-_176046391 7.88 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr22_+_40742497 7.83 ENST00000216194.7
ADSL
adenylosuccinate lyase
chr16_-_2314222 7.81 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr15_-_72523924 7.67 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
PKM
pyruvate kinase, muscle
chr1_+_145883868 7.67 ENST00000447947.2
GPR89C
G protein-coupled receptor 89C
chr5_-_86708670 7.64 ENST00000504878.1
CCNH
cyclin H
chr12_-_14956396 7.61 ENST00000535328.1
ENST00000261167.2
WBP11
WW domain binding protein 11
chr14_-_23504432 7.59 ENST00000425762.2
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr20_-_49575058 7.53 ENST00000371584.4
ENST00000371583.5
ENST00000413082.1
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr11_-_102323740 7.51 ENST00000398136.2
TMEM123
transmembrane protein 123
chr14_+_35591928 7.49 ENST00000605870.1
ENST00000557404.3
KIAA0391
KIAA0391
chr14_-_23504337 7.48 ENST00000361611.6
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr4_+_113568207 7.44 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr19_+_50180409 7.42 ENST00000391851.4
PRMT1
protein arginine methyltransferase 1
chr4_-_72649763 7.33 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr22_+_40742512 7.25 ENST00000454266.2
ENST00000342312.6
ADSL
adenylosuccinate lyase
chr3_-_107777208 7.18 ENST00000398258.3
CD47
CD47 molecule
chr12_+_53693812 7.13 ENST00000549488.1
C12orf10
chromosome 12 open reading frame 10
chr5_+_138609782 7.09 ENST00000361059.2
ENST00000514694.1
ENST00000504203.1
ENST00000502929.1
ENST00000394800.2
ENST00000509644.1
ENST00000505016.1
MATR3
matrin 3
chr12_+_20963632 7.04 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr5_-_86708833 7.02 ENST00000256897.4
CCNH
cyclin H
chr22_+_24951436 7.01 ENST00000215829.3
SNRPD3
small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr11_-_47447970 6.98 ENST00000298852.3
ENST00000530912.1
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr2_+_234637754 6.98 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr14_-_71107921 6.96 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr11_-_122931881 6.93 ENST00000526110.1
ENST00000227378.3
HSPA8
heat shock 70kDa protein 8
chr3_-_64009102 6.90 ENST00000478185.1
ENST00000482510.1
ENST00000497323.1
ENST00000492933.1
ENST00000295901.4
PSMD6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr18_+_3252206 6.90 ENST00000578562.2
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr13_+_28519343 6.79 ENST00000381026.3
ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr19_-_14945933 6.78 ENST00000322301.3
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr15_-_77376269 6.77 ENST00000558745.1
TSPAN3
tetraspanin 3
chr3_-_145878954 6.77 ENST00000282903.5
ENST00000360060.3
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr9_-_69229650 6.75 ENST00000416428.1
CBWD6
COBW domain containing 6
chr4_-_103749179 6.73 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr12_+_4647950 6.68 ENST00000321524.7
ENST00000543041.1
ENST00000228843.9
ENST00000352618.4
ENST00000544927.1
RAD51AP1
RAD51 associated protein 1
chr13_+_29233218 6.67 ENST00000380842.4
POMP
proteasome maturation protein
chr12_+_64798095 6.66 ENST00000332707.5
XPOT
exportin, tRNA
chrX_+_13707235 6.64 ENST00000464506.1
RAB9A
RAB9A, member RAS oncogene family
chr12_+_117013656 6.61 ENST00000556529.1
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr2_+_102413726 6.58 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr12_+_20963647 6.58 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr15_-_66679019 6.58 ENST00000568216.1
ENST00000562124.1
ENST00000570251.1
TIPIN
TIMELESS interacting protein
chr3_+_52245458 6.56 ENST00000459884.1
ALAS1
aminolevulinate, delta-, synthase 1
chr11_+_18417813 6.54 ENST00000540430.1
ENST00000379412.5
LDHA
lactate dehydrogenase A
chr1_-_200589859 6.53 ENST00000367350.4
KIF14
kinesin family member 14
chr3_-_185538849 6.51 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_-_151735937 6.50 ENST00000368829.3
ENST00000368830.3
MRPL9
mitochondrial ribosomal protein L9
chr2_-_190044480 6.46 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr19_-_20748541 6.43 ENST00000427401.4
ENST00000594419.1
ZNF737
zinc finger protein 737
chr2_-_225362533 6.38 ENST00000451538.1
CUL3
cullin 3
chr19_-_49121054 6.36 ENST00000546623.1
ENST00000084795.5
RPL18
ribosomal protein L18
chr7_+_55177416 6.30 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr10_+_47894572 6.29 ENST00000355876.5
FAM21B
family with sequence similarity 21, member B
chr13_+_30002846 6.29 ENST00000542829.1
MTUS2
microtubule associated tumor suppressor candidate 2
chr10_+_5135981 6.28 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chrX_-_106243451 6.24 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr11_+_17316870 6.23 ENST00000458064.2
NUCB2
nucleobindin 2
chr2_+_201997492 6.22 ENST00000494258.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr5_+_138609441 6.21 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
MATR3
matrin 3
chr14_-_54908043 6.19 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr12_+_21525818 6.13 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP
islet amyloid polypeptide
chr8_+_31497271 6.09 ENST00000520407.1
NRG1
neuregulin 1
chr10_+_122610687 6.04 ENST00000263461.6
WDR11
WD repeat domain 11
chr7_-_32529973 6.03 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr10_+_17686124 6.02 ENST00000377524.3
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr15_+_66679155 6.00 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr6_-_131321863 5.99 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr1_-_95391315 5.97 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr20_+_56964253 5.88 ENST00000395802.3
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr4_+_83956312 5.86 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COPS4
COP9 signalosome subunit 4
chr2_-_74735707 5.79 ENST00000233630.6
PCGF1
polycomb group ring finger 1
chr15_-_75249793 5.79 ENST00000322177.5
RPP25
ribonuclease P/MRP 25kDa subunit
chr2_-_191115229 5.78 ENST00000409820.2
ENST00000410045.1
HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr1_-_6420737 5.75 ENST00000541130.1
ENST00000377845.3
ACOT7
acyl-CoA thioesterase 7
chr6_-_24667180 5.73 ENST00000545995.1
TDP2
tyrosyl-DNA phosphodiesterase 2
chr3_+_138340067 5.71 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr11_-_47447767 5.69 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr3_+_105086056 5.64 ENST00000472644.2
ALCAM
activated leukocyte cell adhesion molecule
chr14_-_67826486 5.60 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr11_-_62609281 5.54 ENST00000525239.1
ENST00000538098.2
WDR74
WD repeat domain 74
chr8_-_101719159 5.53 ENST00000520868.1
ENST00000522658.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr1_+_24018269 5.53 ENST00000374550.3
RPL11
ribosomal protein L11
chr14_+_61201445 5.50 ENST00000261245.4
ENST00000539616.2
MNAT1
MNAT CDK-activating kinase assembly factor 1
chr2_-_225434538 5.50 ENST00000409096.1
CUL3
cullin 3
chr7_-_123198284 5.46 ENST00000355749.2
NDUFA5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr4_-_17513851 5.46 ENST00000281243.5
QDPR
quinoid dihydropteridine reductase
chr2_+_234621551 5.44 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr2_+_187454749 5.41 ENST00000261023.3
ENST00000374907.3
ITGAV
integrin, alpha V
chr4_-_103749205 5.40 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr8_-_141810634 5.37 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr5_-_122372354 5.35 ENST00000306442.4
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr4_+_75230853 5.34 ENST00000244869.2
EREG
epiregulin
chr1_+_110546700 5.32 ENST00000359172.3
ENST00000393614.4
AHCYL1
adenosylhomocysteinase-like 1
chr8_-_29208183 5.31 ENST00000240100.2
DUSP4
dual specificity phosphatase 4
chr1_-_145826450 5.27 ENST00000462900.2
GPR89A
G protein-coupled receptor 89A
chr1_-_54405773 5.22 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr1_-_54411255 5.22 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr4_-_69215467 5.18 ENST00000579690.1
YTHDC1
YTH domain containing 1
chr15_+_48624300 5.17 ENST00000455976.2
ENST00000559540.1
DUT
deoxyuridine triphosphatase
chr10_+_115674530 5.16 ENST00000451472.1
AL162407.1
CDNA FLJ20147 fis, clone COL07954; HCG1781466; Uncharacterized protein
chr6_-_13621126 5.14 ENST00000600057.1
AL441883.1
Uncharacterized protein
chr2_-_27886460 5.13 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
SUPT7L
suppressor of Ty 7 (S. cerevisiae)-like
chr2_-_150444116 5.13 ENST00000428879.1
ENST00000422782.2
MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr20_-_54967187 5.07 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA
aurora kinase A
chr4_+_169418195 5.05 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr8_-_91095099 5.04 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr11_+_134201768 5.02 ENST00000535456.2
ENST00000339772.7
GLB1L2
galactosidase, beta 1-like 2
chr11_-_102401469 5.02 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr20_-_49575081 4.97 ENST00000371588.5
ENST00000371582.4
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr1_-_35450897 4.85 ENST00000373337.3
ZMYM6NB
ZMYM6 neighbor
chr19_+_24009879 4.84 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr9_+_33795533 4.70 ENST00000379405.3
PRSS3
protease, serine, 3
chr16_-_66764119 4.69 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr3_+_149192475 4.62 ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr8_-_101718991 4.61 ENST00000517990.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr6_+_114178512 4.60 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr9_-_70490107 4.57 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5
COBW domain containing 5
chr15_+_69706643 4.56 ENST00000352331.4
ENST00000260363.4
KIF23
kinesin family member 23
chr1_+_155179012 4.56 ENST00000609421.1
MTX1
metaxin 1
chr7_-_127983877 4.55 ENST00000415472.2
ENST00000478061.1
ENST00000223073.2
ENST00000459726.1
RBM28
RNA binding motif protein 28
chr2_+_234580525 4.55 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr7_+_16793160 4.50 ENST00000262067.4
TSPAN13
tetraspanin 13
chr2_+_130737223 4.47 ENST00000410061.2
RAB6C
RAB6C, member RAS oncogene family
chr11_+_44117260 4.46 ENST00000358681.4
EXT2
exostosin glycosyltransferase 2
chr2_+_161993412 4.46 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr3_+_105085734 4.46 ENST00000306107.5
ALCAM
activated leukocyte cell adhesion molecule
chr14_-_74959978 4.45 ENST00000541064.1
NPC2
Niemann-Pick disease, type C2
chr5_+_125758865 4.42 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr1_+_214776516 4.41 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr7_-_86849883 4.39 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr7_-_22862406 4.39 ENST00000372879.4
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 15.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
4.6 13.9 GO:0002188 translation reinitiation(GO:0002188)
3.9 19.5 GO:0070980 biphenyl catabolic process(GO:0070980)
3.7 14.7 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
3.6 14.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
3.3 19.8 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
3.2 22.5 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
3.2 19.0 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
3.0 11.9 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
2.9 17.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
2.7 2.7 GO:0006789 bilirubin conjugation(GO:0006789)
2.7 8.0 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
2.5 10.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
2.5 12.5 GO:0019348 dolichol metabolic process(GO:0019348)
2.4 14.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
2.3 9.3 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
2.3 9.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
2.2 8.8 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
2.2 8.7 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
2.1 8.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
2.1 8.4 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
2.1 6.3 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
2.0 8.0 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
2.0 8.0 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
1.9 5.7 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.9 9.3 GO:0051552 flavone metabolic process(GO:0051552)
1.9 14.9 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
1.8 9.2 GO:0070585 protein localization to mitochondrion(GO:0070585)
1.8 5.5 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
1.8 5.3 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
1.8 8.8 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
1.7 5.2 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
1.7 6.7 GO:0043248 proteasome assembly(GO:0043248)
1.6 9.9 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
1.6 6.5 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
1.5 10.7 GO:0061738 late endosomal microautophagy(GO:0061738)
1.5 14.7 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
1.4 4.3 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
1.4 5.5 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
1.4 4.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
1.4 4.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
1.3 4.0 GO:0006106 fumarate metabolic process(GO:0006106)
1.3 6.6 GO:0048478 replication fork protection(GO:0048478)
1.3 6.5 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
1.3 20.9 GO:0000338 protein deneddylation(GO:0000338)
1.3 3.9 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
1.3 6.4 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.2 11.2 GO:0030091 protein repair(GO:0030091)
1.2 16.9 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
1.2 8.3 GO:0046485 ether lipid metabolic process(GO:0046485)
1.2 15.2 GO:0052695 cellular glucuronidation(GO:0052695)
1.2 5.8 GO:0006574 valine catabolic process(GO:0006574)
1.1 8.0 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
1.1 4.6 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.1 10.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.1 11.2 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.1 19.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.0 3.1 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.0 3.1 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
1.0 4.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
1.0 4.0 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
1.0 6.0 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
1.0 6.0 GO:0090170 regulation of Golgi inheritance(GO:0090170)
1.0 2.0 GO:0003213 cardiac right atrium morphogenesis(GO:0003213)
1.0 9.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.9 6.6 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.9 5.7 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.9 3.7 GO:0009189 dTTP biosynthetic process(GO:0006235) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.9 2.8 GO:0035284 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.9 5.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.9 2.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.9 3.5 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.9 6.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.9 4.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.8 5.0 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.8 9.8 GO:0070986 left/right axis specification(GO:0070986)
0.8 10.1 GO:0051451 myoblast migration(GO:0051451)
0.7 4.5 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.7 3.0 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.7 0.7 GO:0009441 glycolate metabolic process(GO:0009441)
0.7 9.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.7 6.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.7 4.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.7 2.0 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.7 6.1 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.7 31.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.6 14.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.6 11.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.6 6.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.6 12.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.6 9.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.6 5.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.6 3.6 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.6 4.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.6 3.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.6 2.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.6 3.4 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.6 6.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.5 2.7 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.5 4.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.5 3.7 GO:0042426 choline catabolic process(GO:0042426)
0.5 68.1 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.5 3.6 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.5 6.6 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.5 1.5 GO:0016199 axon midline choice point recognition(GO:0016199) cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.5 2.9 GO:0051012 microtubule sliding(GO:0051012)
0.5 3.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.5 14.4 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.5 6.5 GO:0006089 lactate metabolic process(GO:0006089)
0.5 20.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.5 15.3 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.5 2.8 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.5 1.8 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.5 0.9 GO:0071233 cellular response to leucine(GO:0071233)
0.5 2.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.5 9.5 GO:0051764 actin crosslink formation(GO:0051764)
0.4 8.1 GO:0008228 opsonization(GO:0008228)
0.4 5.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.4 6.0 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.4 6.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.4 3.8 GO:0051026 chiasma assembly(GO:0051026)
0.4 2.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.4 9.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.4 10.1 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.4 4.4 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.4 6.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.4 1.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.4 8.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.4 11.7 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.4 1.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.4 5.5 GO:0007512 adult heart development(GO:0007512)
0.4 16.2 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.4 0.4 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.4 0.7 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.4 9.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 5.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.3 14.7 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 12.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.3 3.4 GO:0070836 caveola assembly(GO:0070836)
0.3 3.0 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.3 8.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.3 6.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.3 4.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.3 0.9 GO:0060437 lung growth(GO:0060437)
0.3 1.6 GO:0060356 leucine import(GO:0060356)
0.3 2.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.3 0.9 GO:0003274 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) endocardial cushion fusion(GO:0003274)
0.3 0.6 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.3 8.0 GO:0014904 myotube cell development(GO:0014904)
0.3 16.6 GO:0006301 postreplication repair(GO:0006301)
0.3 1.8 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.3 5.8 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.3 9.0 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.3 28.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.3 1.2 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.3 1.5 GO:0007386 compartment pattern specification(GO:0007386)
0.3 3.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.3 1.4 GO:0097338 response to clozapine(GO:0097338)
0.3 0.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.3 2.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.3 6.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 0.8 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.3 11.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.3 2.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 2.0 GO:0015693 magnesium ion transport(GO:0015693)
0.3 2.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.3 5.0 GO:0044849 estrous cycle(GO:0044849)
0.2 3.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.2 8.9 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.2 2.5 GO:0030916 otic vesicle formation(GO:0030916)
0.2 1.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 1.4 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 3.8 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.2 2.3 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.2 16.3 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.2 2.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.2 5.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 4.7 GO:0003334 keratinocyte development(GO:0003334)
0.2 4.0 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.2 4.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 1.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.8 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2 2.3 GO:0051601 exocyst localization(GO:0051601)
0.2 2.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.2 0.8 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.2 1.9 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.2 5.0 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 0.6 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 1.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 2.5 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 1.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 4.2 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.2 0.6 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001)
0.2 1.8 GO:0008210 estrogen metabolic process(GO:0008210)
0.2 2.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2 1.3 GO:0003344 pericardium morphogenesis(GO:0003344)
0.2 6.0 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 0.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 2.9 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.2 2.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.2 4.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 2.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.2 1.0 GO:0016554 cytidine to uridine editing(GO:0016554) DNA deamination(GO:0045006) DNA cytosine deamination(GO:0070383)
0.2 1.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.2 0.3 GO:0036034 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.2 6.7 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 0.8 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 4.9 GO:0051642 centrosome localization(GO:0051642)
0.2 8.1 GO:0051452 intracellular pH reduction(GO:0051452)
0.2 1.1 GO:0018212 peptidyl-tyrosine phosphorylation(GO:0018108) peptidyl-tyrosine modification(GO:0018212)
0.1 2.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.6 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.1 8.0 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 4.6 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 1.7 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 2.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.9 GO:0009249 protein lipoylation(GO:0009249)
0.1 8.8 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.3 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.1 1.1 GO:0009642 response to light intensity(GO:0009642)
0.1 18.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 11.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 4.1 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 1.3 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 1.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 14.5 GO:0006302 double-strand break repair(GO:0006302)
0.1 5.5 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.1 0.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 0.5 GO:0050955 thermoception(GO:0050955)
0.1 0.6 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.1 5.0 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 0.5 GO:0046185 aldehyde catabolic process(GO:0046185)
0.1 6.6 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.1 4.6 GO:0042246 tissue regeneration(GO:0042246)
0.1 0.9 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 1.9 GO:0006379 mRNA cleavage(GO:0006379)
0.1 1.3 GO:0036315 cellular response to sterol(GO:0036315)
0.1 0.8 GO:0016559 peroxisome fission(GO:0016559) protein import into peroxisome membrane(GO:0045046)
0.1 1.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 2.6 GO:0070849 response to epidermal growth factor(GO:0070849) cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 3.0 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.1 0.8 GO:0051289 protein homotetramerization(GO:0051289)
0.1 0.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.9 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 1.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 0.7 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.6 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 5.5 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 0.6 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 1.3 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 0.2 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 1.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.4 GO:0035264 multicellular organism growth(GO:0035264)
0.1 4.3 GO:0070527 platelet aggregation(GO:0070527)
0.1 1.7 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 6.5 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.4 GO:0006414 translational elongation(GO:0006414)
0.1 2.3 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.5 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 1.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.8 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.1 0.6 GO:0051493 regulation of cytoskeleton organization(GO:0051493)
0.1 3.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 1.2 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.0 1.9 GO:1902400 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.8 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.3 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 1.6 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.3 GO:0001701 in utero embryonic development(GO:0001701)
0.0 1.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.5 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 1.3 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 2.1 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 2.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.6 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 3.5 GO:0030183 B cell differentiation(GO:0030183)
0.0 3.5 GO:0001764 neuron migration(GO:0001764)
0.0 0.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.3 GO:0036260 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 0.4 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 0.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.8 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.8 GO:0021766 hippocampus development(GO:0021766)
0.0 2.4 GO:0045333 cellular respiration(GO:0045333)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.4 GO:0006833 water transport(GO:0006833)
0.0 5.2 GO:0010608 posttranscriptional regulation of gene expression(GO:0010608)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.7 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.3 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.3 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.8 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
4.0 19.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
3.7 14.7 GO:0070985 TFIIK complex(GO:0070985)
3.2 22.5 GO:0044326 dendritic spine neck(GO:0044326)
2.9 14.5 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
2.8 14.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
2.7 19.0 GO:0034709 methylosome(GO:0034709)
2.7 8.0 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
2.2 6.5 GO:0005588 collagen type V trimer(GO:0005588)
2.1 6.3 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
2.0 6.0 GO:0033565 ESCRT-0 complex(GO:0033565)
1.9 7.7 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
1.9 15.3 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
1.9 18.5 GO:0030126 COPI vesicle coat(GO:0030126)
1.8 7.1 GO:0031417 NatC complex(GO:0031417)
1.7 14.9 GO:0072687 meiotic spindle(GO:0072687)
1.6 8.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
1.4 5.7 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
1.4 4.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
1.3 4.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
1.2 13.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.2 17.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
1.1 9.9 GO:0005827 polar microtubule(GO:0005827)
1.1 4.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.1 12.7 GO:0031595 nuclear proteasome complex(GO:0031595)
1.1 9.5 GO:0061574 ASAP complex(GO:0061574)
1.0 19.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.0 6.9 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
1.0 6.8 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.9 15.1 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.9 4.6 GO:0097149 centralspindlin complex(GO:0097149)
0.9 6.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.8 16.7 GO:0005838 proteasome regulatory particle(GO:0005838)
0.8 5.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.8 7.3 GO:0031298 replication fork protection complex(GO:0031298)
0.7 2.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.7 9.0 GO:0000815 ESCRT III complex(GO:0000815)
0.6 4.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.6 11.2 GO:0097342 ripoptosome(GO:0097342)
0.6 10.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.6 3.0 GO:0097422 tubular endosome(GO:0097422)
0.6 4.0 GO:0000812 Swr1 complex(GO:0000812)
0.6 9.4 GO:0097228 sperm principal piece(GO:0097228)
0.6 4.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.5 5.5 GO:0005675 holo TFIIH complex(GO:0005675)
0.5 1.9 GO:0030914 STAGA complex(GO:0030914)
0.5 10.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.4 7.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.4 2.0 GO:0097255 R2TP complex(GO:0097255)
0.4 4.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.4 3.2 GO:0030990 intraciliary transport particle(GO:0030990)
0.4 20.1 GO:0008180 COP9 signalosome(GO:0008180)
0.4 4.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.4 9.8 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.4 2.5 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4 4.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.3 4.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 2.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.3 6.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.3 5.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 8.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.3 31.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 16.4 GO:0031430 M band(GO:0031430)
0.3 2.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.3 1.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.3 3.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 1.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 9.6 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.3 20.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 3.6 GO:0005577 fibrinogen complex(GO:0005577)
0.3 14.8 GO:0016235 aggresome(GO:0016235)
0.3 13.3 GO:0005871 kinesin complex(GO:0005871)
0.3 5.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.3 2.1 GO:0070552 BRISC complex(GO:0070552)
0.3 16.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.3 37.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.3 2.5 GO:0000243 commitment complex(GO:0000243)
0.2 3.5 GO:0031932 TORC2 complex(GO:0031932)
0.2 12.5 GO:0001772 immunological synapse(GO:0001772)
0.2 0.7 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 11.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 26.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 4.0 GO:0005839 proteasome core complex(GO:0005839)
0.2 9.8 GO:0002102 podosome(GO:0002102)
0.2 6.1 GO:0030673 axolemma(GO:0030673)
0.2 4.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 4.0 GO:0005685 U1 snRNP(GO:0005685)
0.2 1.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2 1.6 GO:0061700 GATOR2 complex(GO:0061700)
0.2 1.3 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.2 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.2 6.6 GO:0000421 autophagosome membrane(GO:0000421)
0.2 2.6 GO:0097470 ribbon synapse(GO:0097470)
0.2 1.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.2 5.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 5.3 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.2 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.9 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 5.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 4.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 2.4 GO:0043073 germ cell nucleus(GO:0043073)
0.2 6.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 1.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.2 13.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 1.1 GO:0044194 cytolytic granule(GO:0044194)
0.2 13.1 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.2 3.8 GO:0000795 synaptonemal complex(GO:0000795)
0.1 1.9 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 9.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 2.3 GO:0000145 exocyst(GO:0000145)
0.1 20.4 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 5.0 GO:0005776 autophagosome(GO:0005776)
0.1 1.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 7.7 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.4 GO:0001740 Barr body(GO:0001740)
0.1 0.3 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 1.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 8.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 2.9 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.1 0.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 4.1 GO:0043034 costamere(GO:0043034)
0.1 8.8 GO:0032432 actin filament bundle(GO:0032432)
0.1 0.4 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 7.3 GO:0016459 myosin complex(GO:0016459)
0.1 5.8 GO:0014704 intercalated disc(GO:0014704)
0.1 8.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 5.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 15.0 GO:0005681 spliceosomal complex(GO:0005681)
0.1 9.5 GO:0030496 midbody(GO:0030496)
0.1 3.1 GO:0072686 mitotic spindle(GO:0072686)
0.1 4.8 GO:0043195 terminal bouton(GO:0043195)
0.1 1.3 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.6 GO:0032433 filopodium tip(GO:0032433)
0.1 2.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 2.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 2.7 GO:0000786 nucleosome(GO:0000786)
0.1 5.5 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.5 GO:0005604 basement membrane(GO:0005604)
0.1 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 42.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 12.6 GO:0010008 endosome membrane(GO:0010008)
0.0 8.9 GO:0005770 late endosome(GO:0005770)
0.0 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 3.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.6 GO:0045095 keratin filament(GO:0045095)
0.0 1.0 GO:0035869 ciliary transition zone(GO:0035869)
0.0 2.8 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 4.5 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.0 GO:1902494 catalytic complex(GO:1902494)
0.0 2.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 4.8 GO:0005769 early endosome(GO:0005769)
0.0 17.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.3 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.3 GO:0090544 BAF-type complex(GO:0090544)
0.0 3.7 GO:0043209 myelin sheath(GO:0043209)
0.0 4.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 5.4 GO:0005819 spindle(GO:0005819)
0.0 0.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 3.1 GO:0016605 PML body(GO:0016605)
0.0 7.1 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 1.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.9 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.8 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
4.3 17.2 GO:0004743 pyruvate kinase activity(GO:0004743)
4.2 12.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
3.6 14.5 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
3.3 9.9 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
3.0 18.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
3.0 11.9 GO:0031208 POZ domain binding(GO:0031208)
2.7 27.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
2.3 7.0 GO:0071209 U7 snRNA binding(GO:0071209)
2.2 6.6 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
2.1 6.2 GO:0033149 FFAT motif binding(GO:0033149)
2.1 12.4 GO:0005499 vitamin D binding(GO:0005499)
1.9 7.7 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
1.9 5.7 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.9 15.1 GO:0016842 amidine-lyase activity(GO:0016842)
1.9 18.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.8 14.7 GO:0004111 creatine kinase activity(GO:0004111)
1.8 7.4 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
1.8 19.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.8 5.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.7 5.2 GO:0004170 dUTP diphosphatase activity(GO:0004170)
1.7 57.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
1.7 40.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
1.7 8.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
1.5 7.7 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
1.5 1.5 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
1.4 4.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.4 4.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
1.3 20.3 GO:0004526 ribonuclease P activity(GO:0004526)
1.3 6.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.3 7.5 GO:0004447 iodide peroxidase activity(GO:0004447)
1.2 6.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.2 8.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.2 20.8 GO:0016289 CoA hydrolase activity(GO:0016289)
1.2 12.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
1.1 3.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.1 5.5 GO:0070404 NADH binding(GO:0070404)
1.0 4.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
1.0 11.9 GO:1990459 transferrin receptor binding(GO:1990459)
1.0 4.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.0 7.9 GO:0045504 dynein heavy chain binding(GO:0045504)
1.0 20.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.9 3.8 GO:0008431 vitamin E binding(GO:0008431)
0.9 6.5 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.9 5.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.9 26.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.9 8.0 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.8 14.9 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.8 2.3 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.8 9.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.7 10.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.7 4.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.7 3.4 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.6 6.9 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.6 5.0 GO:0004565 beta-galactosidase activity(GO:0004565)
0.6 3.7 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.6 6.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.6 6.0 GO:0042731 PH domain binding(GO:0042731)
0.6 10.1 GO:0008494 translation activator activity(GO:0008494)
0.6 0.6 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.6 2.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 18.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.6 22.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.6 4.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.6 2.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.6 6.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.6 5.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.6 10.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.6 5.5 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.5 14.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.5 2.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.5 3.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.5 24.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.5 8.7 GO:0070513 death domain binding(GO:0070513)
0.5 6.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.5 1.8 GO:0017040 ceramidase activity(GO:0017040)
0.5 1.8 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.4 13.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 4.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.4 3.5 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.4 4.4 GO:0015266 protein channel activity(GO:0015266)
0.4 12.9 GO:0070064 proline-rich region binding(GO:0070064)
0.4 3.0 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.4 1.7 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.4 9.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.4 3.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.4 5.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.4 8.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.4 1.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.4 1.1 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.4 1.5 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.4 11.2 GO:0005123 death receptor binding(GO:0005123)
0.4 4.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 7.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 5.4 GO:0008432 JUN kinase binding(GO:0008432)
0.3 2.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.3 2.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.3 13.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.3 5.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 7.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.3 4.5 GO:0043295 glutathione binding(GO:0043295)
0.3 1.8 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.3 2.0 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.3 3.0 GO:0004312 fatty acid synthase activity(GO:0004312)
0.3 4.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.3 0.8 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.3 4.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.3 0.8 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.3 17.9 GO:0035064 methylated histone binding(GO:0035064)
0.3 2.0 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 4.0 GO:0070628 proteasome binding(GO:0070628)
0.2 3.0 GO:0034452 dynactin binding(GO:0034452)
0.2 1.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 5.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 1.4 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.2 0.9 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.2 17.7 GO:0019003 GDP binding(GO:0019003)
0.2 2.8 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 1.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 2.7 GO:0015248 sterol transporter activity(GO:0015248)
0.2 1.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.2 1.7 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 42.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 2.0 GO:0051425 PTB domain binding(GO:0051425)
0.2 4.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 5.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 4.4 GO:0070840 dynein complex binding(GO:0070840)
0.2 1.3 GO:0008142 oxysterol binding(GO:0008142)
0.2 13.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 1.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 2.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 8.8 GO:0019894 kinesin binding(GO:0019894)
0.2 1.3 GO:0045499 chemorepellent activity(GO:0045499)
0.2 4.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 0.5 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2 5.3 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.2 4.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 6.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 2.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 10.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 2.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 2.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 0.8 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 2.0 GO:0048018 receptor agonist activity(GO:0048018)
0.1 2.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.8 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 8.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.7 GO:0008430 selenium binding(GO:0008430)
0.1 8.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 3.7 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 2.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 4.6 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.3 GO:0016160 amylase activity(GO:0016160)
0.1 0.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 4.7 GO:0031491 nucleosome binding(GO:0031491)
0.1 1.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.5 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 8.0 GO:0002020 protease binding(GO:0002020)
0.1 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 4.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 0.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 8.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 3.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 2.5 GO:0017069 snRNA binding(GO:0017069)
0.1 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.7 GO:0016421 CoA carboxylase activity(GO:0016421)
0.1 7.6 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 1.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 3.2 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.3 GO:0070728 leucine binding(GO:0070728)
0.1 0.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 3.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.8 GO:0017166 vinculin binding(GO:0017166)
0.1 0.7 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.8 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 3.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 3.7 GO:0046332 SMAD binding(GO:0046332)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 21.6 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 1.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0015250 water channel activity(GO:0015250)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 5.8 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.3 GO:0005507 copper ion binding(GO:0005507)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 1.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.8 GO:0017046 peptide hormone binding(GO:0017046)
0.0 2.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 1.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 2.5 GO:0003924 GTPase activity(GO:0003924)
0.0 0.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 19.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 36.9 PID AURORA B PATHWAY Aurora B signaling
0.6 18.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.4 19.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.4 20.4 PID BARD1 PATHWAY BARD1 signaling events
0.4 26.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.4 11.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 37.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 13.5 PID CD40 PATHWAY CD40/CD40L signaling
0.3 11.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 5.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 13.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 9.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 16.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 5.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 22.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 7.9 PID ATR PATHWAY ATR signaling pathway
0.2 9.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 4.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 10.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 7.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 5.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 3.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 6.6 PID CDC42 PATHWAY CDC42 signaling events
0.1 3.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 2.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 4.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 2.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 0.8 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 2.3 PID INSULIN PATHWAY Insulin Pathway
0.1 2.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 4.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 6.0 PID CMYB PATHWAY C-MYB transcription factor network
0.1 4.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.4 PID ATM PATHWAY ATM pathway
0.0 2.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.0 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 2.6 PID E2F PATHWAY E2F transcription factor network
0.0 1.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 49.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.9 18.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
1.8 25.8 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
1.1 17.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
1.0 15.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.9 16.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.9 12.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.9 26.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.9 15.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.8 14.4 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.8 12.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.8 17.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.7 57.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.7 18.5 REACTOME KINESINS Genes involved in Kinesins
0.7 23.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.7 18.8 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.6 14.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.6 5.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.5 8.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.5 12.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.4 4.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4 12.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.4 6.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.4 12.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.4 9.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.4 11.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.4 6.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.4 12.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 21.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 3.1 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.3 6.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 21.3 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.3 6.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 3.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 8.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 9.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.2 4.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 6.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.2 3.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 12.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 6.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 30.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 2.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 1.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 3.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 1.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 4.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 9.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 3.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 11.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 3.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 2.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 2.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 3.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 3.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 2.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 15.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 9.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 2.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 3.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 3.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 8.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 3.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 1.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.9 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 2.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 3.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 4.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 2.3 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 2.0 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 2.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins