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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for HOXC13
Z-value: 1.08
Motif logo
Transcription factors associated with HOXC13
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HOXC13
|
ENSG00000123364.3 | homeobox C13 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXC13 | hg19_v2_chr12_+_54332535_54332636 | 0.53 | 6.3e-17 | Click! |
Activity profile of HOXC13 motif
Sorted Z-values of HOXC13 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_112127981 | 95.00 |
ENST00000486726.2
|
RP11-231E6.1
|
RP11-231E6.1 |
| chr12_-_91539918 | 31.44 |
ENST00000548218.1
|
DCN
|
decorin |
| chr5_-_79287060 | 28.04 |
ENST00000512560.1
ENST00000509852.1 ENST00000512528.1 |
MTX3
|
metaxin 3 |
| chr4_+_106631966 | 26.82 |
ENST00000360505.5
ENST00000510865.1 ENST00000509336.1 |
GSTCD
|
glutathione S-transferase, C-terminal domain containing |
| chr4_+_175204818 | 24.14 |
ENST00000503780.1
|
CEP44
|
centrosomal protein 44kDa |
| chr1_+_90460661 | 20.23 |
ENST00000340281.4
ENST00000361911.5 ENST00000370447.3 ENST00000455342.2 |
ZNF326
|
zinc finger protein 326 |
| chr6_+_151042224 | 20.20 |
ENST00000358517.2
|
PLEKHG1
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 1 |
| chr3_-_195310802 | 19.75 |
ENST00000421243.1
ENST00000453131.1 |
APOD
|
apolipoprotein D |
| chr11_-_104480019 | 17.74 |
ENST00000536529.1
ENST00000545630.1 ENST00000538641.1 |
RP11-886D15.1
|
RP11-886D15.1 |
| chr2_-_177502254 | 16.44 |
ENST00000339037.3
|
AC017048.3
|
long intergenic non-protein coding RNA 1116 |
| chr6_-_33041378 | 15.20 |
ENST00000428995.1
|
HLA-DPA1
|
major histocompatibility complex, class II, DP alpha 1 |
| chr12_-_91546926 | 14.73 |
ENST00000550758.1
|
DCN
|
decorin |
| chr19_+_16999654 | 14.17 |
ENST00000248076.3
|
F2RL3
|
coagulation factor II (thrombin) receptor-like 3 |
| chr6_-_33239712 | 13.53 |
ENST00000436044.2
|
VPS52
|
vacuolar protein sorting 52 homolog (S. cerevisiae) |
| chr11_-_85565906 | 12.56 |
ENST00000544076.1
|
AP000974.1
|
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein |
| chr19_+_7011509 | 12.41 |
ENST00000377296.3
|
AC025278.1
|
Uncharacterized protein |
| chr11_+_61891445 | 11.69 |
ENST00000394818.3
ENST00000533896.1 ENST00000278849.4 |
INCENP
|
inner centromere protein antigens 135/155kDa |
| chr4_+_95679072 | 11.51 |
ENST00000515059.1
|
BMPR1B
|
bone morphogenetic protein receptor, type IB |
| chr22_+_23101182 | 10.98 |
ENST00000390312.2
|
IGLV2-14
|
immunoglobulin lambda variable 2-14 |
| chr7_-_152373216 | 9.99 |
ENST00000359321.1
|
XRCC2
|
X-ray repair complementing defective repair in Chinese hamster cells 2 |
| chr17_-_2415169 | 9.63 |
ENST00000263092.6
ENST00000538844.1 ENST00000576976.1 |
METTL16
|
methyltransferase like 16 |
| chr19_+_21264980 | 9.61 |
ENST00000596053.1
ENST00000597086.1 ENST00000596143.1 ENST00000596367.1 ENST00000601416.1 |
ZNF714
|
zinc finger protein 714 |
| chr2_+_89986318 | 9.58 |
ENST00000491977.1
|
IGKV2D-29
|
immunoglobulin kappa variable 2D-29 |
| chr3_-_155461515 | 9.56 |
ENST00000399242.2
|
AC104472.1
|
CDNA FLJ26134 fis, clone TMS03713; Uncharacterized protein |
| chr15_+_71184931 | 9.48 |
ENST00000560369.1
ENST00000260382.5 |
LRRC49
|
leucine rich repeat containing 49 |
| chr1_+_43766642 | 9.40 |
ENST00000372476.3
|
TIE1
|
tyrosine kinase with immunoglobulin-like and EGF-like domains 1 |
| chr4_-_71532339 | 9.26 |
ENST00000254801.4
|
IGJ
|
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides |
| chr19_+_45409011 | 8.95 |
ENST00000252486.4
ENST00000446996.1 ENST00000434152.1 |
APOE
|
apolipoprotein E |
| chr19_-_18632861 | 8.82 |
ENST00000262809.4
|
ELL
|
elongation factor RNA polymerase II |
| chr19_+_13858593 | 8.65 |
ENST00000221554.8
|
CCDC130
|
coiled-coil domain containing 130 |
| chr6_-_49681235 | 8.34 |
ENST00000339139.4
|
CRISP2
|
cysteine-rich secretory protein 2 |
| chr22_+_39916558 | 8.01 |
ENST00000337304.2
ENST00000396680.1 |
ATF4
|
activating transcription factor 4 |
| chr1_+_158815588 | 7.88 |
ENST00000438394.1
|
MNDA
|
myeloid cell nuclear differentiation antigen |
| chr15_+_71185148 | 7.61 |
ENST00000443425.2
ENST00000560755.1 |
LRRC49
|
leucine rich repeat containing 49 |
| chr3_-_123339418 | 7.59 |
ENST00000583087.1
|
MYLK
|
myosin light chain kinase |
| chr6_-_11807277 | 7.20 |
ENST00000379415.2
|
ADTRP
|
androgen-dependent TFPI-regulating protein |
| chr12_-_114841703 | 7.16 |
ENST00000526441.1
|
TBX5
|
T-box 5 |
| chr6_-_52628271 | 7.14 |
ENST00000493422.1
|
GSTA2
|
glutathione S-transferase alpha 2 |
| chr3_-_123339343 | 7.10 |
ENST00000578202.1
|
MYLK
|
myosin light chain kinase |
| chr14_-_82089405 | 6.93 |
ENST00000554211.1
|
RP11-799P8.1
|
RP11-799P8.1 |
| chr14_-_50065882 | 6.64 |
ENST00000539688.1
|
AL139099.1
|
Full-length cDNA clone CS0DK012YO09 of HeLa cells of Homo sapiens (human); Uncharacterized protein |
| chr8_+_95565947 | 6.62 |
ENST00000523011.1
|
RP11-267M23.4
|
RP11-267M23.4 |
| chr8_+_133879193 | 6.58 |
ENST00000377869.1
ENST00000220616.4 |
TG
|
thyroglobulin |
| chr5_-_64920115 | 6.45 |
ENST00000381018.3
ENST00000274327.7 |
TRIM23
|
tripartite motif containing 23 |
| chr20_-_52687059 | 6.26 |
ENST00000371435.2
ENST00000395961.3 |
BCAS1
|
breast carcinoma amplified sequence 1 |
| chr1_-_149832704 | 6.18 |
ENST00000392933.1
ENST00000369157.2 ENST00000392932.4 |
HIST2H4B
|
histone cluster 2, H4b |
| chr12_-_53207842 | 6.12 |
ENST00000458244.2
|
KRT4
|
keratin 4 |
| chr4_+_88720698 | 5.97 |
ENST00000226284.5
|
IBSP
|
integrin-binding sialoprotein |
| chr10_-_79398250 | 5.89 |
ENST00000286627.5
|
KCNMA1
|
potassium large conductance calcium-activated channel, subfamily M, alpha member 1 |
| chr13_+_103451399 | 5.85 |
ENST00000257336.1
ENST00000448849.2 |
BIVM
|
basic, immunoglobulin-like variable motif containing |
| chr9_+_137979506 | 5.82 |
ENST00000539529.1
ENST00000392991.4 ENST00000371793.3 |
OLFM1
|
olfactomedin 1 |
| chr10_-_79397740 | 5.78 |
ENST00000372440.1
ENST00000480683.1 |
KCNMA1
|
potassium large conductance calcium-activated channel, subfamily M, alpha member 1 |
| chr5_-_180076580 | 5.77 |
ENST00000502649.1
|
FLT4
|
fms-related tyrosine kinase 4 |
| chr10_+_70847852 | 5.76 |
ENST00000242465.3
|
SRGN
|
serglycin |
| chrX_-_38186775 | 5.74 |
ENST00000339363.3
ENST00000309513.3 ENST00000338898.3 ENST00000342811.3 ENST00000378505.2 |
RPGR
|
retinitis pigmentosa GTPase regulator |
| chr18_-_52989217 | 5.72 |
ENST00000570287.2
|
TCF4
|
transcription factor 4 |
| chr2_+_103035102 | 5.68 |
ENST00000264260.2
|
IL18RAP
|
interleukin 18 receptor accessory protein |
| chr2_+_162016827 | 5.64 |
ENST00000429217.1
ENST00000406287.1 ENST00000402568.1 |
TANK
|
TRAF family member-associated NFKB activator |
| chr6_-_33239612 | 5.53 |
ENST00000482399.1
ENST00000445902.2 |
VPS52
|
vacuolar protein sorting 52 homolog (S. cerevisiae) |
| chr12_+_102514019 | 5.45 |
ENST00000537257.1
ENST00000358383.5 ENST00000392911.2 |
PARPBP
|
PARP1 binding protein |
| chr5_-_41261540 | 5.41 |
ENST00000263413.3
|
C6
|
complement component 6 |
| chr14_-_106963409 | 5.30 |
ENST00000390621.2
|
IGHV1-45
|
immunoglobulin heavy variable 1-45 |
| chr12_-_52828147 | 5.26 |
ENST00000252245.5
|
KRT75
|
keratin 75 |
| chr19_-_6279932 | 5.22 |
ENST00000252674.7
|
MLLT1
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 |
| chr11_-_85376121 | 5.21 |
ENST00000527447.1
|
CREBZF
|
CREB/ATF bZIP transcription factor |
| chr19_-_47987419 | 5.20 |
ENST00000536339.1
ENST00000595554.1 ENST00000600271.1 ENST00000338134.3 |
KPTN
|
kaptin (actin binding protein) |
| chr17_-_56769382 | 5.14 |
ENST00000240361.8
ENST00000349033.5 ENST00000389934.3 |
TEX14
|
testis expressed 14 |
| chr4_+_118955500 | 5.09 |
ENST00000296499.5
|
NDST3
|
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 |
| chr19_-_11456935 | 4.95 |
ENST00000590788.1
ENST00000586590.1 ENST00000589555.1 ENST00000586956.1 ENST00000593256.2 ENST00000447337.1 ENST00000591677.1 ENST00000586701.1 ENST00000589655.1 |
TMEM205
RAB3D
|
transmembrane protein 205 RAB3D, member RAS oncogene family |
| chr12_-_9360966 | 4.91 |
ENST00000261336.2
|
PZP
|
pregnancy-zone protein |
| chr3_-_112320749 | 4.91 |
ENST00000610103.1
|
RP11-572C15.6
|
RP11-572C15.6 |
| chr4_+_70894130 | 4.90 |
ENST00000526767.1
ENST00000530128.1 ENST00000381057.3 |
HTN3
|
histatin 3 |
| chr1_+_149804218 | 4.69 |
ENST00000610125.1
|
HIST2H4A
|
histone cluster 2, H4a |
| chr17_+_3118915 | 4.64 |
ENST00000304094.1
|
OR1A1
|
olfactory receptor, family 1, subfamily A, member 1 |
| chr3_-_172241250 | 4.63 |
ENST00000420541.2
ENST00000241261.2 |
TNFSF10
|
tumor necrosis factor (ligand) superfamily, member 10 |
| chr7_+_80275752 | 4.62 |
ENST00000419819.2
|
CD36
|
CD36 molecule (thrombospondin receptor) |
| chr20_+_36946029 | 4.60 |
ENST00000417318.1
|
BPI
|
bactericidal/permeability-increasing protein |
| chr1_-_47407111 | 4.58 |
ENST00000371904.4
|
CYP4A11
|
cytochrome P450, family 4, subfamily A, polypeptide 11 |
| chr10_-_79398127 | 4.55 |
ENST00000372443.1
|
KCNMA1
|
potassium large conductance calcium-activated channel, subfamily M, alpha member 1 |
| chr9_-_5304432 | 4.54 |
ENST00000416837.1
ENST00000308420.3 |
RLN2
|
relaxin 2 |
| chrX_+_41583408 | 4.53 |
ENST00000302548.4
|
GPR82
|
G protein-coupled receptor 82 |
| chr11_+_61015594 | 4.50 |
ENST00000451616.2
|
PGA5
|
pepsinogen 5, group I (pepsinogen A) |
| chr10_+_51549498 | 4.43 |
ENST00000358559.2
ENST00000298239.6 |
MSMB
|
microseminoprotein, beta- |
| chr11_+_94706804 | 4.36 |
ENST00000335080.5
|
KDM4D
|
lysine (K)-specific demethylase 4D |
| chr12_-_118796910 | 4.34 |
ENST00000541186.1
ENST00000539872.1 |
TAOK3
|
TAO kinase 3 |
| chr19_+_859654 | 4.33 |
ENST00000592860.1
|
CFD
|
complement factor D (adipsin) |
| chr11_+_3011093 | 4.30 |
ENST00000332881.2
|
AC131971.1
|
HCG1782999; PRO0943; Uncharacterized protein |
| chr3_-_126373929 | 4.26 |
ENST00000523403.1
ENST00000524230.2 |
TXNRD3
|
thioredoxin reductase 3 |
| chr15_-_58571445 | 4.24 |
ENST00000558231.1
|
ALDH1A2
|
aldehyde dehydrogenase 1 family, member A2 |
| chr4_-_120243545 | 4.18 |
ENST00000274024.3
|
FABP2
|
fatty acid binding protein 2, intestinal |
| chr8_+_101170563 | 4.13 |
ENST00000520508.1
ENST00000388798.2 |
SPAG1
|
sperm associated antigen 1 |
| chr17_+_29664830 | 4.05 |
ENST00000444181.2
ENST00000417592.2 |
NF1
|
neurofibromin 1 |
| chr7_-_27169801 | 4.04 |
ENST00000511914.1
|
HOXA4
|
homeobox A4 |
| chr11_+_30252549 | 4.03 |
ENST00000254122.3
ENST00000417547.1 |
FSHB
|
follicle stimulating hormone, beta polypeptide |
| chr4_+_70861647 | 4.02 |
ENST00000246895.4
ENST00000381060.2 |
STATH
|
statherin |
| chr6_+_20534672 | 3.94 |
ENST00000274695.4
ENST00000378624.4 |
CDKAL1
|
CDK5 regulatory subunit associated protein 1-like 1 |
| chr5_+_150020214 | 3.93 |
ENST00000307662.4
|
SYNPO
|
synaptopodin |
| chr11_+_63606373 | 3.89 |
ENST00000402010.2
ENST00000315032.8 ENST00000377809.4 ENST00000413835.2 ENST00000377810.3 |
MARK2
|
MAP/microtubule affinity-regulating kinase 2 |
| chr17_-_8286484 | 3.87 |
ENST00000582556.1
ENST00000584164.1 ENST00000293842.5 ENST00000584343.1 ENST00000578812.1 ENST00000583011.1 |
RPL26
|
ribosomal protein L26 |
| chr2_+_48796120 | 3.85 |
ENST00000394754.1
|
STON1-GTF2A1L
|
STON1-GTF2A1L readthrough |
| chr18_+_61554932 | 3.81 |
ENST00000299502.4
ENST00000457692.1 ENST00000413956.1 |
SERPINB2
|
serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| chr11_+_118175132 | 3.80 |
ENST00000361763.4
|
CD3E
|
CD3e molecule, epsilon (CD3-TCR complex) |
| chr19_+_36545833 | 3.80 |
ENST00000401500.2
ENST00000270301.7 ENST00000427823.2 |
WDR62
|
WD repeat domain 62 |
| chr10_+_13628933 | 3.79 |
ENST00000417658.1
ENST00000320054.4 |
PRPF18
|
pre-mRNA processing factor 18 |
| chr1_-_89591749 | 3.77 |
ENST00000370466.3
|
GBP2
|
guanylate binding protein 2, interferon-inducible |
| chr15_-_44069741 | 3.74 |
ENST00000319359.3
|
ELL3
|
elongation factor RNA polymerase II-like 3 |
| chr9_+_21967137 | 3.68 |
ENST00000441769.2
|
C9orf53
|
chromosome 9 open reading frame 53 |
| chr10_-_70287172 | 3.62 |
ENST00000539557.1
|
SLC25A16
|
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 |
| chr15_-_99789736 | 3.62 |
ENST00000560235.1
ENST00000394132.2 ENST00000560860.1 ENST00000558078.1 ENST00000394136.1 ENST00000262074.4 ENST00000558613.1 ENST00000394130.1 ENST00000560772.1 |
TTC23
|
tetratricopeptide repeat domain 23 |
| chr18_-_5544241 | 3.57 |
ENST00000341928.2
ENST00000540638.2 |
EPB41L3
|
erythrocyte membrane protein band 4.1-like 3 |
| chr1_+_153003671 | 3.57 |
ENST00000307098.4
|
SPRR1B
|
small proline-rich protein 1B |
| chr20_+_37590942 | 3.55 |
ENST00000373325.2
ENST00000252011.3 ENST00000373323.4 |
DHX35
|
DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| chr10_-_51371321 | 3.51 |
ENST00000602930.1
|
AGAP8
|
ArfGAP with GTPase domain, ankyrin repeat and PH domain 8 |
| chr1_+_192544857 | 3.43 |
ENST00000367459.3
ENST00000469578.2 |
RGS1
|
regulator of G-protein signaling 1 |
| chr2_+_162016916 | 3.40 |
ENST00000405852.1
|
TANK
|
TRAF family member-associated NFKB activator |
| chr4_+_71248795 | 3.39 |
ENST00000304915.3
|
SMR3B
|
submaxillary gland androgen regulated protein 3B |
| chr11_+_60995849 | 3.33 |
ENST00000537932.1
|
PGA4
|
pepsinogen 4, group I (pepsinogen A) |
| chr21_+_39628655 | 3.33 |
ENST00000398925.1
ENST00000398928.1 ENST00000328656.4 ENST00000443341.1 |
KCNJ15
|
potassium inwardly-rectifying channel, subfamily J, member 15 |
| chr1_-_55266926 | 3.18 |
ENST00000371276.4
|
TTC22
|
tetratricopeptide repeat domain 22 |
| chr15_-_78538025 | 3.14 |
ENST00000560817.1
|
ACSBG1
|
acyl-CoA synthetase bubblegum family member 1 |
| chr7_-_38389573 | 3.12 |
ENST00000390344.2
|
TRGV5
|
T cell receptor gamma variable 5 |
| chr16_+_81348528 | 3.03 |
ENST00000568107.2
|
GAN
|
gigaxonin |
| chr14_-_106668095 | 3.01 |
ENST00000390606.2
|
IGHV3-20
|
immunoglobulin heavy variable 3-20 |
| chr10_-_70287231 | 2.98 |
ENST00000609923.1
|
SLC25A16
|
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 |
| chr8_-_95274536 | 2.97 |
ENST00000297596.2
ENST00000396194.2 |
GEM
|
GTP binding protein overexpressed in skeletal muscle |
| chr1_-_47407136 | 2.95 |
ENST00000462347.1
ENST00000371905.1 ENST00000310638.4 |
CYP4A11
|
cytochrome P450, family 4, subfamily A, polypeptide 11 |
| chr11_+_62037622 | 2.94 |
ENST00000227918.2
ENST00000525380.1 |
SCGB2A2
|
secretoglobin, family 2A, member 2 |
| chr12_-_13248598 | 2.94 |
ENST00000337630.6
ENST00000545699.1 |
GSG1
|
germ cell associated 1 |
| chr11_+_49050504 | 2.92 |
ENST00000332682.7
|
TRIM49B
|
tripartite motif containing 49B |
| chr12_-_13248562 | 2.90 |
ENST00000457134.2
ENST00000537302.1 |
GSG1
|
germ cell associated 1 |
| chr7_+_80275621 | 2.89 |
ENST00000426978.1
ENST00000432207.1 |
CD36
|
CD36 molecule (thrombospondin receptor) |
| chr9_-_21351377 | 2.88 |
ENST00000380210.1
|
IFNA6
|
interferon, alpha 6 |
| chr6_-_32784687 | 2.80 |
ENST00000447394.1
ENST00000438763.2 |
HLA-DOB
|
major histocompatibility complex, class II, DO beta |
| chr7_+_80275953 | 2.80 |
ENST00000538969.1
ENST00000544133.1 ENST00000433696.2 |
CD36
|
CD36 molecule (thrombospondin receptor) |
| chr18_-_52989525 | 2.77 |
ENST00000457482.3
|
TCF4
|
transcription factor 4 |
| chr2_+_210444142 | 2.77 |
ENST00000360351.4
ENST00000361559.4 |
MAP2
|
microtubule-associated protein 2 |
| chr6_-_146057144 | 2.70 |
ENST00000367519.3
|
EPM2A
|
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| chr13_-_46964177 | 2.69 |
ENST00000389908.3
|
KIAA0226L
|
KIAA0226-like |
| chr3_+_129159039 | 2.69 |
ENST00000507564.1
ENST00000431818.2 ENST00000504021.1 ENST00000349441.2 ENST00000348417.2 ENST00000440957.2 |
IFT122
|
intraflagellar transport 122 homolog (Chlamydomonas) |
| chr1_+_171107241 | 2.69 |
ENST00000236166.3
|
FMO6P
|
flavin containing monooxygenase 6 pseudogene |
| chr2_+_162016804 | 2.68 |
ENST00000392749.2
ENST00000440506.1 |
TANK
|
TRAF family member-associated NFKB activator |
| chr17_-_39553844 | 2.67 |
ENST00000251645.2
|
KRT31
|
keratin 31 |
| chr12_-_13248705 | 2.63 |
ENST00000396310.2
|
GSG1
|
germ cell associated 1 |
| chrX_+_49687216 | 2.62 |
ENST00000376088.3
|
CLCN5
|
chloride channel, voltage-sensitive 5 |
| chr19_+_21106081 | 2.62 |
ENST00000300540.3
ENST00000595854.1 ENST00000601284.1 ENST00000328178.8 ENST00000599885.1 ENST00000596476.1 ENST00000345030.6 |
ZNF85
|
zinc finger protein 85 |
| chr9_-_37034028 | 2.59 |
ENST00000520281.1
ENST00000446742.1 ENST00000522003.1 ENST00000523145.1 ENST00000414447.1 ENST00000377847.2 ENST00000377853.2 ENST00000377852.2 ENST00000523241.1 ENST00000520154.1 ENST00000358127.4 |
PAX5
|
paired box 5 |
| chr5_-_39270725 | 2.59 |
ENST00000512138.1
ENST00000512982.1 ENST00000540520.1 |
FYB
|
FYN binding protein |
| chrX_+_133733457 | 2.58 |
ENST00000440614.1
|
RP11-308B5.2
|
RP11-308B5.2 |
| chr16_+_28565230 | 2.56 |
ENST00000317058.3
|
CCDC101
|
coiled-coil domain containing 101 |
| chr4_+_128702969 | 2.53 |
ENST00000508776.1
ENST00000439123.2 |
HSPA4L
|
heat shock 70kDa protein 4-like |
| chr2_+_138721850 | 2.50 |
ENST00000329366.4
ENST00000280097.3 |
HNMT
|
histamine N-methyltransferase |
| chr11_-_89541743 | 2.44 |
ENST00000329758.1
|
TRIM49
|
tripartite motif containing 49 |
| chr12_-_57630873 | 2.42 |
ENST00000556732.1
|
NDUFA4L2
|
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
| chr1_+_246887349 | 2.39 |
ENST00000366510.3
|
SCCPDH
|
saccharopine dehydrogenase (putative) |
| chr7_+_106505912 | 2.38 |
ENST00000359195.3
|
PIK3CG
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma |
| chr6_-_46922659 | 2.37 |
ENST00000265417.7
|
GPR116
|
G protein-coupled receptor 116 |
| chr7_+_57509877 | 2.27 |
ENST00000420713.1
|
ZNF716
|
zinc finger protein 716 |
| chr1_+_17559776 | 2.26 |
ENST00000537499.1
ENST00000413717.2 ENST00000536552.1 |
PADI1
|
peptidyl arginine deiminase, type I |
| chr6_+_29426230 | 2.22 |
ENST00000442615.1
|
OR2H1
|
olfactory receptor, family 2, subfamily H, member 1 |
| chr10_+_52750930 | 2.21 |
ENST00000401604.2
|
PRKG1
|
protein kinase, cGMP-dependent, type I |
| chr11_-_124670550 | 2.20 |
ENST00000239614.4
|
MSANTD2
|
Myb/SANT-like DNA-binding domain containing 2 |
| chr7_+_106505696 | 2.16 |
ENST00000440650.2
ENST00000496166.1 ENST00000473541.1 |
PIK3CG
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma |
| chr1_+_174128639 | 2.16 |
ENST00000251507.4
|
RABGAP1L
|
RAB GTPase activating protein 1-like |
| chr11_+_89764274 | 2.16 |
ENST00000448984.1
ENST00000432771.1 |
TRIM49C
|
tripartite motif containing 49C |
| chr1_+_12976450 | 2.16 |
ENST00000361079.2
|
PRAMEF7
|
PRAME family member 7 |
| chr2_+_138722028 | 2.06 |
ENST00000280096.5
|
HNMT
|
histamine N-methyltransferase |
| chr5_-_58571935 | 2.03 |
ENST00000503258.1
|
PDE4D
|
phosphodiesterase 4D, cAMP-specific |
| chr4_-_170533723 | 2.02 |
ENST00000510533.1
ENST00000439128.2 ENST00000511633.1 ENST00000512193.1 ENST00000507142.1 |
NEK1
|
NIMA-related kinase 1 |
| chr9_-_95244781 | 1.97 |
ENST00000375544.3
ENST00000375543.1 ENST00000395538.3 ENST00000450139.2 |
ASPN
|
asporin |
| chr1_+_55107449 | 1.96 |
ENST00000421030.2
ENST00000545244.1 ENST00000339553.5 ENST00000409996.1 ENST00000454855.2 |
MROH7
|
maestro heat-like repeat family member 7 |
| chr16_-_68033356 | 1.94 |
ENST00000393847.1
ENST00000573808.1 ENST00000572624.1 |
DPEP2
|
dipeptidase 2 |
| chr5_-_180076613 | 1.88 |
ENST00000261937.6
ENST00000393347.3 |
FLT4
|
fms-related tyrosine kinase 4 |
| chr17_-_3496171 | 1.87 |
ENST00000399756.4
|
TRPV1
|
transient receptor potential cation channel, subfamily V, member 1 |
| chr1_+_78511586 | 1.86 |
ENST00000370759.3
|
GIPC2
|
GIPC PDZ domain containing family, member 2 |
| chr15_+_71228826 | 1.82 |
ENST00000558456.1
ENST00000560158.2 ENST00000558808.1 ENST00000559806.1 ENST00000559069.1 |
LRRC49
|
leucine rich repeat containing 49 |
| chr12_-_4647606 | 1.76 |
ENST00000261250.3
ENST00000541014.1 ENST00000545746.1 ENST00000542080.1 |
C12orf4
|
chromosome 12 open reading frame 4 |
| chr22_+_32439019 | 1.76 |
ENST00000266088.4
|
SLC5A1
|
solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| chr10_-_69455873 | 1.76 |
ENST00000433211.2
|
CTNNA3
|
catenin (cadherin-associated protein), alpha 3 |
| chrY_+_23698778 | 1.69 |
ENST00000303902.5
|
RBMY1A1
|
RNA binding motif protein, Y-linked, family 1, member A1 |
| chr10_-_6019984 | 1.64 |
ENST00000525219.2
|
IL15RA
|
interleukin 15 receptor, alpha |
| chr3_-_99569821 | 1.61 |
ENST00000487087.1
|
FILIP1L
|
filamin A interacting protein 1-like |
| chr1_+_206858232 | 1.59 |
ENST00000294981.4
|
MAPKAPK2
|
mitogen-activated protein kinase-activated protein kinase 2 |
| chr14_-_106725723 | 1.58 |
ENST00000390609.2
|
IGHV3-23
|
immunoglobulin heavy variable 3-23 |
| chr17_+_43861680 | 1.55 |
ENST00000314537.5
|
CRHR1
|
corticotropin releasing hormone receptor 1 |
| chr14_-_106816253 | 1.55 |
ENST00000390615.2
|
IGHV3-33
|
immunoglobulin heavy variable 3-33 |
| chr8_-_86290333 | 1.52 |
ENST00000521846.1
ENST00000523022.1 ENST00000524324.1 ENST00000519991.1 ENST00000520663.1 ENST00000517590.1 ENST00000522579.1 ENST00000522814.1 ENST00000522662.1 ENST00000523858.1 ENST00000519129.1 |
CA1
|
carbonic anhydrase I |
| chr1_+_213224572 | 1.40 |
ENST00000543470.1
ENST00000366960.3 ENST00000366959.3 ENST00000543354.1 |
RPS6KC1
|
ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
| chr8_+_1993152 | 1.35 |
ENST00000262113.4
|
MYOM2
|
myomesin 2 |
| chr5_-_169725231 | 1.30 |
ENST00000046794.5
|
LCP2
|
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
| chr1_-_150208320 | 1.29 |
ENST00000534220.1
|
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr6_+_19837592 | 1.27 |
ENST00000378700.3
|
ID4
|
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| chr3_-_46037299 | 1.25 |
ENST00000296137.2
|
FYCO1
|
FYVE and coiled-coil domain containing 1 |
| chr3_+_185080908 | 1.23 |
ENST00000265026.3
|
MAP3K13
|
mitogen-activated protein kinase kinase kinase 13 |
| chr17_-_39646116 | 1.18 |
ENST00000328119.6
|
KRT36
|
keratin 36 |
| chr6_+_160327974 | 1.18 |
ENST00000252660.4
|
MAS1
|
MAS1 oncogene |
| chrX_+_113818545 | 1.17 |
ENST00000371951.1
ENST00000276198.1 ENST00000371950.3 |
HTR2C
|
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled |
| chr6_-_76782371 | 1.07 |
ENST00000369950.3
ENST00000369963.3 |
IMPG1
|
interphotoreceptor matrix proteoglycan 1 |
| chr2_-_86850949 | 1.03 |
ENST00000237455.4
|
RNF103
|
ring finger protein 103 |
| chr3_-_52864680 | 1.00 |
ENST00000406595.1
ENST00000485816.1 ENST00000434759.3 ENST00000346281.5 ENST00000266041.4 |
ITIH4
|
inter-alpha-trypsin inhibitor heavy chain family, member 4 |
| chr1_-_154150651 | 1.00 |
ENST00000302206.5
|
TPM3
|
tropomyosin 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXC13
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.6 | 19.8 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 6.4 | 19.1 | GO:0048611 | ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) |
| 3.8 | 46.2 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 3.0 | 9.0 | GO:1902995 | regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) |
| 2.7 | 8.0 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 2.4 | 7.2 | GO:0003218 | cardiac left ventricle formation(GO:0003218) |
| 2.3 | 11.5 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 2.2 | 8.8 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 1.9 | 9.6 | GO:0080009 | mRNA methylation(GO:0080009) |
| 1.9 | 5.8 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 1.8 | 14.7 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 1.8 | 14.2 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 1.7 | 6.6 | GO:0003095 | pressure natriuresis(GO:0003095) |
| 1.5 | 18.1 | GO:0060083 | smooth muscle contraction involved in micturition(GO:0060083) |
| 1.5 | 10.3 | GO:2000332 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 1.4 | 5.4 | GO:0001970 | positive regulation of activation of membrane attack complex(GO:0001970) |
| 1.3 | 4.0 | GO:0061534 | gamma-aminobutyric acid secretion, neurotransmission(GO:0061534) |
| 1.3 | 3.8 | GO:0071048 | nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048) |
| 1.3 | 7.6 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 1.0 | 3.0 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 1.0 | 5.0 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.9 | 2.8 | GO:0002581 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) |
| 0.9 | 4.4 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 0.9 | 5.1 | GO:0032466 | negative regulation of cytokinesis(GO:0032466) |
| 0.8 | 5.5 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.8 | 3.9 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.8 | 3.8 | GO:0002913 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) |
| 0.8 | 4.6 | GO:0001692 | histamine metabolic process(GO:0001692) |
| 0.8 | 4.5 | GO:0010897 | negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252) |
| 0.7 | 6.6 | GO:0015705 | iodide transport(GO:0015705) |
| 0.7 | 2.7 | GO:0035720 | signal transduction downstream of smoothened(GO:0007227) intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 0.7 | 2.0 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.7 | 5.2 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.6 | 5.8 | GO:0003190 | atrioventricular valve formation(GO:0003190) |
| 0.6 | 7.6 | GO:0060312 | regulation of blood vessel remodeling(GO:0060312) |
| 0.6 | 4.0 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 0.6 | 3.4 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.5 | 3.6 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.5 | 5.1 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.5 | 4.2 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.5 | 24.0 | GO:0032784 | regulation of DNA-templated transcription, elongation(GO:0032784) |
| 0.5 | 2.3 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 0.4 | 4.0 | GO:0046541 | saliva secretion(GO:0046541) |
| 0.4 | 7.9 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
| 0.4 | 4.6 | GO:0043031 | negative regulation of macrophage activation(GO:0043031) |
| 0.3 | 3.9 | GO:0099563 | modification of synaptic structure(GO:0099563) |
| 0.3 | 1.5 | GO:0051458 | corticosterone secretion(GO:0035934) corticotropin secretion(GO:0051458) regulation of corticosterone secretion(GO:2000852) |
| 0.3 | 1.3 | GO:0061107 | prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107) |
| 0.3 | 1.8 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) |
| 0.2 | 2.0 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) |
| 0.2 | 9.4 | GO:0045026 | plasma membrane fusion(GO:0045026) |
| 0.2 | 4.7 | GO:2000269 | regulation of fibroblast apoptotic process(GO:2000269) |
| 0.2 | 1.2 | GO:0010513 | positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) |
| 0.2 | 1.6 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.2 | 2.0 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.2 | 0.9 | GO:0061146 | Peyer's patch morphogenesis(GO:0061146) |
| 0.2 | 4.6 | GO:0097296 | activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296) |
| 0.2 | 4.1 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
| 0.2 | 2.6 | GO:0021670 | lateral ventricle development(GO:0021670) |
| 0.2 | 15.2 | GO:0032729 | positive regulation of interferon-gamma production(GO:0032729) |
| 0.2 | 1.3 | GO:1901098 | regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098) |
| 0.2 | 0.6 | GO:0034343 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
| 0.2 | 1.8 | GO:0086073 | cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
| 0.2 | 4.3 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.2 | 22.6 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.2 | 17.3 | GO:0070268 | cornification(GO:0070268) |
| 0.2 | 2.9 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
| 0.2 | 7.5 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.1 | 2.2 | GO:0060087 | relaxation of vascular smooth muscle(GO:0060087) |
| 0.1 | 3.1 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.1 | 4.9 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.1 | 5.7 | GO:0042073 | intraciliary transport(GO:0042073) |
| 0.1 | 0.7 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.1 | 19.5 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.1 | 4.2 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 0.1 | 4.3 | GO:0000305 | response to oxygen radical(GO:0000305) |
| 0.1 | 3.8 | GO:0007099 | centriole replication(GO:0007099) |
| 0.1 | 2.7 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
| 0.1 | 11.7 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.1 | 2.6 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 0.3 | GO:0001555 | oocyte growth(GO:0001555) |
| 0.1 | 3.9 | GO:0051646 | mitochondrion localization(GO:0051646) |
| 0.1 | 1.2 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
| 0.1 | 3.3 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 0.5 | GO:0002933 | lipid hydroxylation(GO:0002933) |
| 0.1 | 2.8 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.1 | 3.9 | GO:0006400 | tRNA modification(GO:0006400) |
| 0.1 | 5.2 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.1 | 1.8 | GO:0043304 | regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304) |
| 0.1 | 2.3 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.1 | 4.5 | GO:0030819 | positive regulation of cAMP biosynthetic process(GO:0030819) |
| 0.1 | 7.8 | GO:0007586 | digestion(GO:0007586) |
| 0.1 | 6.0 | GO:0030282 | bone mineralization(GO:0030282) |
| 0.0 | 1.0 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.0 | 0.4 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.0 | 3.8 | GO:0071357 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.0 | 2.4 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.0 | 0.7 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.0 | 6.6 | GO:0006839 | mitochondrial transport(GO:0006839) |
| 0.0 | 1.0 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.0 | 1.3 | GO:0045576 | mast cell activation(GO:0045576) |
| 0.0 | 1.5 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.0 | 0.7 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 1.7 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 0.7 | GO:0006337 | nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) |
| 0.0 | 9.4 | GO:0009615 | response to virus(GO:0009615) |
| 0.0 | 7.6 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
| 0.0 | 1.9 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 1.3 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 0.3 | GO:0006366 | transcription from RNA polymerase II promoter(GO:0006366) |
| 0.0 | 1.6 | GO:0008283 | cell proliferation(GO:0008283) |
| 0.0 | 2.0 | GO:0060271 | cilium morphogenesis(GO:0060271) |
| 0.0 | 0.3 | GO:0002377 | immunoglobulin production(GO:0002377) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.7 | 20.2 | GO:0044609 | DBIRD complex(GO:0044609) |
| 4.8 | 19.1 | GO:1990745 | EARP complex(GO:1990745) |
| 3.3 | 46.2 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 3.0 | 9.0 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 2.3 | 11.7 | GO:0000801 | central element(GO:0000801) |
| 1.5 | 4.5 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 1.3 | 8.0 | GO:1990037 | Lewy body core(GO:1990037) |
| 1.3 | 3.8 | GO:0071020 | post-spliceosomal complex(GO:0071020) |
| 0.9 | 11.5 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.9 | 18.0 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.8 | 7.8 | GO:0097486 | multivesicular body lumen(GO:0097486) |
| 0.6 | 5.4 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.5 | 10.7 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.5 | 2.8 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.4 | 2.7 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.4 | 3.9 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.3 | 3.8 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.3 | 10.3 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.3 | 8.8 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.3 | 5.8 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.3 | 1.3 | GO:0036398 | TCR signalosome(GO:0036398) |
| 0.3 | 11.4 | GO:0045095 | keratin filament(GO:0045095) |
| 0.2 | 4.0 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.2 | 3.6 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.2 | 10.1 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.2 | 14.7 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.2 | 29.0 | GO:0030496 | midbody(GO:0030496) |
| 0.2 | 9.0 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.2 | 2.4 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.2 | 4.4 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.2 | 5.2 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 16.2 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 0.7 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 0.1 | 3.8 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.1 | 1.8 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.1 | 28.0 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.1 | 12.5 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.1 | 4.3 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 1.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 1.9 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.1 | 1.3 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.1 | 2.3 | GO:0032982 | myosin filament(GO:0032982) |
| 0.1 | 2.0 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 3.9 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.1 | 16.4 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.1 | 5.7 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.1 | 3.6 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 1.0 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 1.0 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 1.0 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 1.0 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 3.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 2.0 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 3.5 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 3.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 2.3 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 4.5 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 45.2 | GO:0005615 | extracellular space(GO:0005615) |
| 0.0 | 0.3 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 3.3 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 7.6 | GO:0043235 | receptor complex(GO:0043235) |
| 0.0 | 6.0 | GO:0005813 | centrosome(GO:0005813) |
| 0.0 | 6.7 | GO:0005874 | microtubule(GO:0005874) |
| 0.0 | 2.6 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 2.8 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 2.1 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 1.9 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 4.0 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 18.5 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 3.3 | GO:0005765 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 9.6 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 3.0 | 9.0 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 2.9 | 14.7 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 2.4 | 14.2 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 2.3 | 16.2 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 1.7 | 10.3 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 1.7 | 6.6 | GO:0018685 | alkane 1-monooxygenase activity(GO:0018685) |
| 1.3 | 4.0 | GO:0046848 | hydroxyapatite binding(GO:0046848) |
| 1.3 | 18.0 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 1.3 | 11.5 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 1.3 | 3.8 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 1.3 | 7.6 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.8 | 5.1 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.7 | 8.5 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.6 | 4.5 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.6 | 7.6 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.6 | 46.2 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.5 | 1.9 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) |
| 0.5 | 2.3 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 0.4 | 8.0 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.4 | 2.2 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.4 | 1.8 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.4 | 4.3 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.4 | 19.8 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.4 | 4.2 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.3 | 1.5 | GO:0015056 | corticotrophin-releasing factor receptor activity(GO:0015056) |
| 0.3 | 2.7 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.2 | 2.5 | GO:0042608 | T cell receptor binding(GO:0042608) |
| 0.2 | 1.2 | GO:0001595 | angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945) |
| 0.2 | 4.4 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.2 | 3.1 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.2 | 2.9 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.2 | 20.2 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.2 | 1.8 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.2 | 19.1 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.2 | 1.5 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.2 | 5.0 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.2 | 12.5 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.2 | 3.3 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.2 | 10.1 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.2 | 3.9 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.2 | 4.0 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.2 | 7.5 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 4.6 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.1 | 22.1 | GO:0003823 | antigen binding(GO:0003823) |
| 0.1 | 7.7 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 3.4 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 9.4 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.1 | 2.0 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.1 | 1.2 | GO:0043176 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.1 | 3.9 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.1 | 2.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 4.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 1.9 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.1 | 1.0 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.1 | 2.0 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) structural molecule activity conferring elasticity(GO:0097493) |
| 0.1 | 1.2 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.1 | 1.6 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 6.6 | GO:0015297 | antiporter activity(GO:0015297) |
| 0.1 | 3.4 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.1 | 7.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 3.9 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.1 | 9.1 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 0.5 | GO:0016713 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) |
| 0.1 | 1.9 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 1.5 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 3.5 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.0 | 8.8 | GO:0019902 | phosphatase binding(GO:0019902) |
| 0.0 | 6.0 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 1.3 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 6.2 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.7 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.9 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 3.7 | GO:0035326 | enhancer binding(GO:0035326) |
| 0.0 | 4.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.7 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 9.5 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 0.3 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 0.7 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 1.3 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 1.0 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 1.0 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 4.4 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.0 | 1.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 1.9 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 1.4 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.0 | 1.4 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 55.0 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.8 | 14.2 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.4 | 26.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.4 | 7.6 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.2 | 9.5 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.2 | 11.5 | PID BMP PATHWAY | BMP receptor signaling |
| 0.1 | 2.0 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 8.0 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 4.5 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 4.0 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 4.6 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.1 | 3.3 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.1 | 6.7 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 8.5 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 1.3 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 1.6 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 2.9 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.1 | 2.6 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.1 | 3.4 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 1.9 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 2.5 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 4.1 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 4.0 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.9 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 0.7 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 1.2 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 4.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 46.2 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.9 | 7.2 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.8 | 19.0 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.6 | 8.0 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.5 | 6.6 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.4 | 9.0 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.4 | 7.6 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.3 | 4.5 | REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
| 0.3 | 14.2 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.3 | 11.5 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.3 | 11.1 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.3 | 4.0 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.2 | 10.9 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.2 | 13.4 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.2 | 4.3 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.2 | 8.8 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.2 | 5.4 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.2 | 4.6 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.2 | 5.1 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.2 | 3.3 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.2 | 8.5 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.2 | 7.3 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.1 | 3.9 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.1 | 11.7 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 10.3 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 6.6 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.1 | 1.5 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 1.2 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.1 | 1.6 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.1 | 2.2 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.1 | 3.8 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 1.0 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 3.6 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 2.5 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 1.8 | REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds |
| 0.0 | 3.0 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |