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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXC13

Z-value: 1.08

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Transcription factors associated with HOXC13

Gene Symbol Gene ID Gene Info
HOXC13
ENSG00000123364.3 homeobox C13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC13hg19_v2_chr12_+_54332535_543326360.536.3e-17Click!

Activity profile of HOXC13 motif

Sorted Z-values of HOXC13 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_112127981 95.00 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr12_-_91539918 31.44 ENST00000548218.1
DCN
decorin
chr5_-_79287060 28.04 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
MTX3
metaxin 3
chr4_+_106631966 26.82 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
GSTCD
glutathione S-transferase, C-terminal domain containing
chr4_+_175204818 24.14 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr1_+_90460661 20.23 ENST00000340281.4
ENST00000361911.5
ENST00000370447.3
ENST00000455342.2
ZNF326
zinc finger protein 326
chr6_+_151042224 20.20 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr3_-_195310802 19.75 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr11_-_104480019 17.74 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr2_-_177502254 16.44 ENST00000339037.3
AC017048.3
long intergenic non-protein coding RNA 1116
chr6_-_33041378 15.20 ENST00000428995.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr12_-_91546926 14.73 ENST00000550758.1
DCN
decorin
chr19_+_16999654 14.17 ENST00000248076.3
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr6_-_33239712 13.53 ENST00000436044.2
VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr11_-_85565906 12.56 ENST00000544076.1
AP000974.1
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein
chr19_+_7011509 12.41 ENST00000377296.3
AC025278.1
Uncharacterized protein
chr11_+_61891445 11.69 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP
inner centromere protein antigens 135/155kDa
chr4_+_95679072 11.51 ENST00000515059.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr22_+_23101182 10.98 ENST00000390312.2
IGLV2-14
immunoglobulin lambda variable 2-14
chr7_-_152373216 9.99 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr17_-_2415169 9.63 ENST00000263092.6
ENST00000538844.1
ENST00000576976.1
METTL16
methyltransferase like 16
chr19_+_21264980 9.61 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714
zinc finger protein 714
chr2_+_89986318 9.58 ENST00000491977.1
IGKV2D-29
immunoglobulin kappa variable 2D-29
chr3_-_155461515 9.56 ENST00000399242.2
AC104472.1
CDNA FLJ26134 fis, clone TMS03713; Uncharacterized protein
chr15_+_71184931 9.48 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr1_+_43766642 9.40 ENST00000372476.3
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr4_-_71532339 9.26 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr19_+_45409011 8.95 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE
apolipoprotein E
chr19_-_18632861 8.82 ENST00000262809.4
ELL
elongation factor RNA polymerase II
chr19_+_13858593 8.65 ENST00000221554.8
CCDC130
coiled-coil domain containing 130
chr6_-_49681235 8.34 ENST00000339139.4
CRISP2
cysteine-rich secretory protein 2
chr22_+_39916558 8.01 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr1_+_158815588 7.88 ENST00000438394.1
MNDA
myeloid cell nuclear differentiation antigen
chr15_+_71185148 7.61 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr3_-_123339418 7.59 ENST00000583087.1
MYLK
myosin light chain kinase
chr6_-_11807277 7.20 ENST00000379415.2
ADTRP
androgen-dependent TFPI-regulating protein
chr12_-_114841703 7.16 ENST00000526441.1
TBX5
T-box 5
chr6_-_52628271 7.14 ENST00000493422.1
GSTA2
glutathione S-transferase alpha 2
chr3_-_123339343 7.10 ENST00000578202.1
MYLK
myosin light chain kinase
chr14_-_82089405 6.93 ENST00000554211.1
RP11-799P8.1
RP11-799P8.1
chr14_-_50065882 6.64 ENST00000539688.1
AL139099.1
Full-length cDNA clone CS0DK012YO09 of HeLa cells of Homo sapiens (human); Uncharacterized protein
chr8_+_95565947 6.62 ENST00000523011.1
RP11-267M23.4
RP11-267M23.4
chr8_+_133879193 6.58 ENST00000377869.1
ENST00000220616.4
TG
thyroglobulin
chr5_-_64920115 6.45 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr20_-_52687059 6.26 ENST00000371435.2
ENST00000395961.3
BCAS1
breast carcinoma amplified sequence 1
chr1_-_149832704 6.18 ENST00000392933.1
ENST00000369157.2
ENST00000392932.4
HIST2H4B
histone cluster 2, H4b
chr12_-_53207842 6.12 ENST00000458244.2
KRT4
keratin 4
chr4_+_88720698 5.97 ENST00000226284.5
IBSP
integrin-binding sialoprotein
chr10_-_79398250 5.89 ENST00000286627.5
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr13_+_103451399 5.85 ENST00000257336.1
ENST00000448849.2
BIVM
basic, immunoglobulin-like variable motif containing
chr9_+_137979506 5.82 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
OLFM1
olfactomedin 1
chr10_-_79397740 5.78 ENST00000372440.1
ENST00000480683.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr5_-_180076580 5.77 ENST00000502649.1
FLT4
fms-related tyrosine kinase 4
chr10_+_70847852 5.76 ENST00000242465.3
SRGN
serglycin
chrX_-_38186775 5.74 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
RPGR
retinitis pigmentosa GTPase regulator
chr18_-_52989217 5.72 ENST00000570287.2
TCF4
transcription factor 4
chr2_+_103035102 5.68 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr2_+_162016827 5.64 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr6_-_33239612 5.53 ENST00000482399.1
ENST00000445902.2
VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr12_+_102514019 5.45 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARPBP
PARP1 binding protein
chr5_-_41261540 5.41 ENST00000263413.3
C6
complement component 6
chr14_-_106963409 5.30 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr12_-_52828147 5.26 ENST00000252245.5
KRT75
keratin 75
chr19_-_6279932 5.22 ENST00000252674.7
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr11_-_85376121 5.21 ENST00000527447.1
CREBZF
CREB/ATF bZIP transcription factor
chr19_-_47987419 5.20 ENST00000536339.1
ENST00000595554.1
ENST00000600271.1
ENST00000338134.3
KPTN
kaptin (actin binding protein)
chr17_-_56769382 5.14 ENST00000240361.8
ENST00000349033.5
ENST00000389934.3
TEX14
testis expressed 14
chr4_+_118955500 5.09 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr19_-_11456935 4.95 ENST00000590788.1
ENST00000586590.1
ENST00000589555.1
ENST00000586956.1
ENST00000593256.2
ENST00000447337.1
ENST00000591677.1
ENST00000586701.1
ENST00000589655.1
TMEM205
RAB3D
transmembrane protein 205
RAB3D, member RAS oncogene family
chr12_-_9360966 4.91 ENST00000261336.2
PZP
pregnancy-zone protein
chr3_-_112320749 4.91 ENST00000610103.1
RP11-572C15.6
RP11-572C15.6
chr4_+_70894130 4.90 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr1_+_149804218 4.69 ENST00000610125.1
HIST2H4A
histone cluster 2, H4a
chr17_+_3118915 4.64 ENST00000304094.1
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr3_-_172241250 4.63 ENST00000420541.2
ENST00000241261.2
TNFSF10
tumor necrosis factor (ligand) superfamily, member 10
chr7_+_80275752 4.62 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr20_+_36946029 4.60 ENST00000417318.1
BPI
bactericidal/permeability-increasing protein
chr1_-_47407111 4.58 ENST00000371904.4
CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
chr10_-_79398127 4.55 ENST00000372443.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr9_-_5304432 4.54 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chrX_+_41583408 4.53 ENST00000302548.4
GPR82
G protein-coupled receptor 82
chr11_+_61015594 4.50 ENST00000451616.2
PGA5
pepsinogen 5, group I (pepsinogen A)
chr10_+_51549498 4.43 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chr11_+_94706804 4.36 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr12_-_118796910 4.34 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr19_+_859654 4.33 ENST00000592860.1
CFD
complement factor D (adipsin)
chr11_+_3011093 4.30 ENST00000332881.2
AC131971.1
HCG1782999; PRO0943; Uncharacterized protein
chr3_-_126373929 4.26 ENST00000523403.1
ENST00000524230.2
TXNRD3
thioredoxin reductase 3
chr15_-_58571445 4.24 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr4_-_120243545 4.18 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr8_+_101170563 4.13 ENST00000520508.1
ENST00000388798.2
SPAG1
sperm associated antigen 1
chr17_+_29664830 4.05 ENST00000444181.2
ENST00000417592.2
NF1
neurofibromin 1
chr7_-_27169801 4.04 ENST00000511914.1
HOXA4
homeobox A4
chr11_+_30252549 4.03 ENST00000254122.3
ENST00000417547.1
FSHB
follicle stimulating hormone, beta polypeptide
chr4_+_70861647 4.02 ENST00000246895.4
ENST00000381060.2
STATH
statherin
chr6_+_20534672 3.94 ENST00000274695.4
ENST00000378624.4
CDKAL1
CDK5 regulatory subunit associated protein 1-like 1
chr5_+_150020214 3.93 ENST00000307662.4
SYNPO
synaptopodin
chr11_+_63606373 3.89 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2
MAP/microtubule affinity-regulating kinase 2
chr17_-_8286484 3.87 ENST00000582556.1
ENST00000584164.1
ENST00000293842.5
ENST00000584343.1
ENST00000578812.1
ENST00000583011.1
RPL26
ribosomal protein L26
chr2_+_48796120 3.85 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr18_+_61554932 3.81 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr11_+_118175132 3.80 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr19_+_36545833 3.80 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WDR62
WD repeat domain 62
chr10_+_13628933 3.79 ENST00000417658.1
ENST00000320054.4
PRPF18
pre-mRNA processing factor 18
chr1_-_89591749 3.77 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr15_-_44069741 3.74 ENST00000319359.3
ELL3
elongation factor RNA polymerase II-like 3
chr9_+_21967137 3.68 ENST00000441769.2
C9orf53
chromosome 9 open reading frame 53
chr10_-_70287172 3.62 ENST00000539557.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr15_-_99789736 3.62 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23
tetratricopeptide repeat domain 23
chr18_-_5544241 3.57 ENST00000341928.2
ENST00000540638.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr1_+_153003671 3.57 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr20_+_37590942 3.55 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr10_-_51371321 3.51 ENST00000602930.1
AGAP8
ArfGAP with GTPase domain, ankyrin repeat and PH domain 8
chr1_+_192544857 3.43 ENST00000367459.3
ENST00000469578.2
RGS1
regulator of G-protein signaling 1
chr2_+_162016916 3.40 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr4_+_71248795 3.39 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chr11_+_60995849 3.33 ENST00000537932.1
PGA4
pepsinogen 4, group I (pepsinogen A)
chr21_+_39628655 3.33 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_-_55266926 3.18 ENST00000371276.4
TTC22
tetratricopeptide repeat domain 22
chr15_-_78538025 3.14 ENST00000560817.1
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr7_-_38389573 3.12 ENST00000390344.2
TRGV5
T cell receptor gamma variable 5
chr16_+_81348528 3.03 ENST00000568107.2
GAN
gigaxonin
chr14_-_106668095 3.01 ENST00000390606.2
IGHV3-20
immunoglobulin heavy variable 3-20
chr10_-_70287231 2.98 ENST00000609923.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr8_-_95274536 2.97 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr1_-_47407136 2.95 ENST00000462347.1
ENST00000371905.1
ENST00000310638.4
CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
chr11_+_62037622 2.94 ENST00000227918.2
ENST00000525380.1
SCGB2A2
secretoglobin, family 2A, member 2
chr12_-_13248598 2.94 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chr11_+_49050504 2.92 ENST00000332682.7
TRIM49B
tripartite motif containing 49B
chr12_-_13248562 2.90 ENST00000457134.2
ENST00000537302.1
GSG1
germ cell associated 1
chr7_+_80275621 2.89 ENST00000426978.1
ENST00000432207.1
CD36
CD36 molecule (thrombospondin receptor)
chr9_-_21351377 2.88 ENST00000380210.1
IFNA6
interferon, alpha 6
chr6_-_32784687 2.80 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr7_+_80275953 2.80 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr18_-_52989525 2.77 ENST00000457482.3
TCF4
transcription factor 4
chr2_+_210444142 2.77 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr6_-_146057144 2.70 ENST00000367519.3
EPM2A
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr13_-_46964177 2.69 ENST00000389908.3
KIAA0226L
KIAA0226-like
chr3_+_129159039 2.69 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr1_+_171107241 2.69 ENST00000236166.3
FMO6P
flavin containing monooxygenase 6 pseudogene
chr2_+_162016804 2.68 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr17_-_39553844 2.67 ENST00000251645.2
KRT31
keratin 31
chr12_-_13248705 2.63 ENST00000396310.2
GSG1
germ cell associated 1
chrX_+_49687216 2.62 ENST00000376088.3
CLCN5
chloride channel, voltage-sensitive 5
chr19_+_21106081 2.62 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
ZNF85
zinc finger protein 85
chr9_-_37034028 2.59 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5
paired box 5
chr5_-_39270725 2.59 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chrX_+_133733457 2.58 ENST00000440614.1
RP11-308B5.2
RP11-308B5.2
chr16_+_28565230 2.56 ENST00000317058.3
CCDC101
coiled-coil domain containing 101
chr4_+_128702969 2.53 ENST00000508776.1
ENST00000439123.2
HSPA4L
heat shock 70kDa protein 4-like
chr2_+_138721850 2.50 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr11_-_89541743 2.44 ENST00000329758.1
TRIM49
tripartite motif containing 49
chr12_-_57630873 2.42 ENST00000556732.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_+_246887349 2.39 ENST00000366510.3
SCCPDH
saccharopine dehydrogenase (putative)
chr7_+_106505912 2.38 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr6_-_46922659 2.37 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chr7_+_57509877 2.27 ENST00000420713.1
ZNF716
zinc finger protein 716
chr1_+_17559776 2.26 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1
peptidyl arginine deiminase, type I
chr6_+_29426230 2.22 ENST00000442615.1
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr10_+_52750930 2.21 ENST00000401604.2
PRKG1
protein kinase, cGMP-dependent, type I
chr11_-_124670550 2.20 ENST00000239614.4
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr7_+_106505696 2.16 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr1_+_174128639 2.16 ENST00000251507.4
RABGAP1L
RAB GTPase activating protein 1-like
chr11_+_89764274 2.16 ENST00000448984.1
ENST00000432771.1
TRIM49C
tripartite motif containing 49C
chr1_+_12976450 2.16 ENST00000361079.2
PRAMEF7
PRAME family member 7
chr2_+_138722028 2.06 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr5_-_58571935 2.03 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_170533723 2.02 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
NEK1
NIMA-related kinase 1
chr9_-_95244781 1.97 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr1_+_55107449 1.96 ENST00000421030.2
ENST00000545244.1
ENST00000339553.5
ENST00000409996.1
ENST00000454855.2
MROH7
maestro heat-like repeat family member 7
chr16_-_68033356 1.94 ENST00000393847.1
ENST00000573808.1
ENST00000572624.1
DPEP2
dipeptidase 2
chr5_-_180076613 1.88 ENST00000261937.6
ENST00000393347.3
FLT4
fms-related tyrosine kinase 4
chr17_-_3496171 1.87 ENST00000399756.4
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr1_+_78511586 1.86 ENST00000370759.3
GIPC2
GIPC PDZ domain containing family, member 2
chr15_+_71228826 1.82 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr12_-_4647606 1.76 ENST00000261250.3
ENST00000541014.1
ENST00000545746.1
ENST00000542080.1
C12orf4
chromosome 12 open reading frame 4
chr22_+_32439019 1.76 ENST00000266088.4
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr10_-_69455873 1.76 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chrY_+_23698778 1.69 ENST00000303902.5
RBMY1A1
RNA binding motif protein, Y-linked, family 1, member A1
chr10_-_6019984 1.64 ENST00000525219.2
IL15RA
interleukin 15 receptor, alpha
chr3_-_99569821 1.61 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr1_+_206858232 1.59 ENST00000294981.4
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr14_-_106725723 1.58 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr17_+_43861680 1.55 ENST00000314537.5
CRHR1
corticotropin releasing hormone receptor 1
chr14_-_106816253 1.55 ENST00000390615.2
IGHV3-33
immunoglobulin heavy variable 3-33
chr8_-_86290333 1.52 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1
carbonic anhydrase I
chr1_+_213224572 1.40 ENST00000543470.1
ENST00000366960.3
ENST00000366959.3
ENST00000543354.1
RPS6KC1
ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr8_+_1993152 1.35 ENST00000262113.4
MYOM2
myomesin 2
chr5_-_169725231 1.30 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_-_150208320 1.29 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr6_+_19837592 1.27 ENST00000378700.3
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr3_-_46037299 1.25 ENST00000296137.2
FYCO1
FYVE and coiled-coil domain containing 1
chr3_+_185080908 1.23 ENST00000265026.3
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr17_-_39646116 1.18 ENST00000328119.6
KRT36
keratin 36
chr6_+_160327974 1.18 ENST00000252660.4
MAS1
MAS1 oncogene
chrX_+_113818545 1.17 ENST00000371951.1
ENST00000276198.1
ENST00000371950.3
HTR2C
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
chr6_-_76782371 1.07 ENST00000369950.3
ENST00000369963.3
IMPG1
interphotoreceptor matrix proteoglycan 1
chr2_-_86850949 1.03 ENST00000237455.4
RNF103
ring finger protein 103
chr3_-_52864680 1.00 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
ITIH4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr1_-_154150651 1.00 ENST00000302206.5
TPM3
tropomyosin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.6 19.8 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
6.4 19.1 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
3.8 46.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
3.0 9.0 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
2.7 8.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
2.4 7.2 GO:0003218 cardiac left ventricle formation(GO:0003218)
2.3 11.5 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
2.2 8.8 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
1.9 9.6 GO:0080009 mRNA methylation(GO:0080009)
1.9 5.8 GO:0033364 mast cell secretory granule organization(GO:0033364)
1.8 14.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.8 14.2 GO:0060155 platelet dense granule organization(GO:0060155)
1.7 6.6 GO:0003095 pressure natriuresis(GO:0003095)
1.5 18.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
1.5 10.3 GO:2000332 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
1.4 5.4 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.3 4.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
1.3 3.8 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
1.3 7.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.0 3.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
1.0 5.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.9 2.8 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.9 4.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.9 5.1 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.8 5.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.8 3.9 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.8 3.8 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.8 4.6 GO:0001692 histamine metabolic process(GO:0001692)
0.8 4.5 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.7 6.6 GO:0015705 iodide transport(GO:0015705)
0.7 2.7 GO:0035720 signal transduction downstream of smoothened(GO:0007227) intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.7 2.0 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.7 5.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.6 5.8 GO:0003190 atrioventricular valve formation(GO:0003190)
0.6 7.6 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.6 4.0 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.6 3.4 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.5 3.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.5 5.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.5 4.2 GO:0035799 ureter maturation(GO:0035799)
0.5 24.0 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.5 2.3 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.4 4.0 GO:0046541 saliva secretion(GO:0046541)
0.4 7.9 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.4 4.6 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.3 3.9 GO:0099563 modification of synaptic structure(GO:0099563)
0.3 1.5 GO:0051458 corticosterone secretion(GO:0035934) corticotropin secretion(GO:0051458) regulation of corticosterone secretion(GO:2000852)
0.3 1.3 GO:0061107 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.3 1.8 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.2 2.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 9.4 GO:0045026 plasma membrane fusion(GO:0045026)
0.2 4.7 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.2 1.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 1.6 GO:0044351 macropinocytosis(GO:0044351)
0.2 2.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 0.9 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.2 4.6 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.2 4.1 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.2 2.6 GO:0021670 lateral ventricle development(GO:0021670)
0.2 15.2 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.2 1.3 GO:1901098 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.2 0.6 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 1.8 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2 4.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 22.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 17.3 GO:0070268 cornification(GO:0070268)
0.2 2.9 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 7.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 2.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 3.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 4.9 GO:0050832 defense response to fungus(GO:0050832)
0.1 5.7 GO:0042073 intraciliary transport(GO:0042073)
0.1 0.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 19.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 4.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 4.3 GO:0000305 response to oxygen radical(GO:0000305)
0.1 3.8 GO:0007099 centriole replication(GO:0007099)
0.1 2.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 11.7 GO:0016925 protein sumoylation(GO:0016925)
0.1 2.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.3 GO:0001555 oocyte growth(GO:0001555)
0.1 3.9 GO:0051646 mitochondrion localization(GO:0051646)
0.1 1.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 3.3 GO:0010107 potassium ion import(GO:0010107)
0.1 0.5 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 2.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 3.9 GO:0006400 tRNA modification(GO:0006400)
0.1 5.2 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 1.8 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.1 2.3 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 4.5 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.1 7.8 GO:0007586 digestion(GO:0007586)
0.1 6.0 GO:0030282 bone mineralization(GO:0030282)
0.0 1.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 3.8 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 2.4 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 6.6 GO:0006839 mitochondrial transport(GO:0006839)
0.0 1.0 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 1.3 GO:0045576 mast cell activation(GO:0045576)
0.0 1.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.7 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498)
0.0 9.4 GO:0009615 response to virus(GO:0009615)
0.0 7.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.3 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.3 GO:0006366 transcription from RNA polymerase II promoter(GO:0006366)
0.0 1.6 GO:0008283 cell proliferation(GO:0008283)
0.0 2.0 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.3 GO:0002377 immunoglobulin production(GO:0002377)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 20.2 GO:0044609 DBIRD complex(GO:0044609)
4.8 19.1 GO:1990745 EARP complex(GO:1990745)
3.3 46.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
3.0 9.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
2.3 11.7 GO:0000801 central element(GO:0000801)
1.5 4.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.3 8.0 GO:1990037 Lewy body core(GO:1990037)
1.3 3.8 GO:0071020 post-spliceosomal complex(GO:0071020)
0.9 11.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.9 18.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.8 7.8 GO:0097486 multivesicular body lumen(GO:0097486)
0.6 5.4 GO:0005579 membrane attack complex(GO:0005579)
0.5 10.7 GO:0042588 zymogen granule(GO:0042588)
0.5 2.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 2.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.4 3.9 GO:0097427 microtubule bundle(GO:0097427)
0.3 3.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 10.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 8.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 5.8 GO:0044295 axonal growth cone(GO:0044295)
0.3 1.3 GO:0036398 TCR signalosome(GO:0036398)
0.3 11.4 GO:0045095 keratin filament(GO:0045095)
0.2 4.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 3.6 GO:0033270 paranode region of axon(GO:0033270)
0.2 10.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 14.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 29.0 GO:0030496 midbody(GO:0030496)
0.2 9.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 2.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 4.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 5.2 GO:0032420 stereocilium(GO:0032420)
0.1 16.2 GO:0005901 caveola(GO:0005901)
0.1 0.7 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 3.8 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.8 GO:0005916 fascia adherens(GO:0005916)
0.1 28.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 12.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 4.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 2.3 GO:0032982 myosin filament(GO:0032982)
0.1 2.0 GO:0000242 pericentriolar material(GO:0000242)
0.1 3.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 16.4 GO:0032993 protein-DNA complex(GO:0032993)
0.1 5.7 GO:0036064 ciliary basal body(GO:0036064)
0.1 3.6 GO:0001533 cornified envelope(GO:0001533)
0.1 1.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 3.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 3.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.3 GO:0005882 intermediate filament(GO:0005882)
0.0 4.5 GO:0005923 bicellular tight junction(GO:0005923)
0.0 45.2 GO:0005615 extracellular space(GO:0005615)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 3.3 GO:0005769 early endosome(GO:0005769)
0.0 7.6 GO:0043235 receptor complex(GO:0043235)
0.0 6.0 GO:0005813 centrosome(GO:0005813)
0.0 6.7 GO:0005874 microtubule(GO:0005874)
0.0 2.6 GO:0001650 fibrillar center(GO:0001650)
0.0 2.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 4.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 18.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 3.3 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
3.0 9.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
2.9 14.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
2.4 14.2 GO:0015057 thrombin receptor activity(GO:0015057)
2.3 16.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
1.7 10.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
1.7 6.6 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
1.3 4.0 GO:0046848 hydroxyapatite binding(GO:0046848)
1.3 18.0 GO:0032395 MHC class II receptor activity(GO:0032395)
1.3 11.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
1.3 3.8 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
1.3 7.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.8 5.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.7 8.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.6 4.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.6 7.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.6 46.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.5 1.9 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.5 2.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.4 8.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.4 2.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.4 1.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.4 4.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.4 19.8 GO:0015485 cholesterol binding(GO:0015485)
0.4 4.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.3 1.5 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.3 2.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 2.5 GO:0042608 T cell receptor binding(GO:0042608)
0.2 1.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.2 4.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 3.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 2.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 20.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 1.8 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 19.1 GO:0019905 syntaxin binding(GO:0019905)
0.2 1.5 GO:0004064 arylesterase activity(GO:0004064)
0.2 5.0 GO:0031489 myosin V binding(GO:0031489)
0.2 12.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.2 3.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 10.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 3.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 4.0 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.2 7.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 4.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 22.1 GO:0003823 antigen binding(GO:0003823)
0.1 7.7 GO:0005518 collagen binding(GO:0005518)
0.1 3.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 9.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 2.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 1.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 3.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 2.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 4.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.0 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 2.0 GO:0051371 muscle alpha-actinin binding(GO:0051371) structural molecule activity conferring elasticity(GO:0097493)
0.1 1.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 6.6 GO:0015297 antiporter activity(GO:0015297)
0.1 3.4 GO:0005504 fatty acid binding(GO:0005504)
0.1 7.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 9.1 GO:0005179 hormone activity(GO:0005179)
0.1 0.5 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 1.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 3.5 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 8.8 GO:0019902 phosphatase binding(GO:0019902)
0.0 6.0 GO:0005178 integrin binding(GO:0005178)
0.0 1.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 6.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.0 3.7 GO:0035326 enhancer binding(GO:0035326)
0.0 4.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 9.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 1.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 4.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.4 GO:0035091 phosphatidylinositol binding(GO:0035091)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 55.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.8 14.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.4 26.4 PID AURORA B PATHWAY Aurora B signaling
0.4 7.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 9.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 11.5 PID BMP PATHWAY BMP receptor signaling
0.1 2.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 8.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 4.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 4.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 4.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 3.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 6.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 8.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 2.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 3.4 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 1.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 4.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 4.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 4.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 46.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.9 7.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.8 19.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.6 8.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.5 6.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.4 9.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 7.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 4.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.3 14.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.3 11.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.3 11.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.3 4.0 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 10.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 13.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 4.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 8.8 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.2 5.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 4.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 5.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 3.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 8.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 7.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 3.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 11.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 10.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 6.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 2.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 3.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.8 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 3.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation