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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXD11_HOXA11

Z-value: 0.85

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Transcription factors associated with HOXD11_HOXA11

Gene Symbol Gene ID Gene Info
ENSG00000128713.11 homeobox D11
ENSG00000005073.5 homeobox A11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA11hg19_v2_chr7_-_27224842_27224872,
hg19_v2_chr7_-_27224795_27224840
-0.152.7e-02Click!
HOXD11hg19_v2_chr2_+_176972000_176972025-0.143.4e-02Click!

Activity profile of HOXD11_HOXA11 motif

Sorted Z-values of HOXD11_HOXA11 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_74728998 15.24 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
myelin basic protein
chr4_+_41258786 11.81 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr16_+_15031300 10.74 ENST00000328085.6
nuclear pore complex interacting protein family, member A1
chr14_-_60097297 9.95 ENST00000395090.1
reticulon 1
chr11_-_796197 9.32 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr1_-_28527152 9.09 ENST00000321830.5
Uncharacterized protein
chr5_+_36608422 9.09 ENST00000381918.3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_-_60097524 8.77 ENST00000342503.4
reticulon 1
chr2_-_51259292 8.48 ENST00000401669.2
neurexin 1
chr2_-_51259229 8.32 ENST00000405472.3
neurexin 1
chr9_+_137979506 8.26 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
olfactomedin 1
chr8_+_107738240 7.82 ENST00000449762.2
ENST00000297447.6
oxidation resistance 1
chr12_+_6833237 7.81 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
COP9 signalosome subunit 7A
chr12_+_6833437 7.64 ENST00000534947.1
ENST00000541866.1
ENST00000534877.1
ENST00000538753.1
COP9 signalosome subunit 7A
chr2_-_207023918 7.26 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr5_-_73937244 7.10 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ectodermal-neural cortex 1 (with BTB domain)
chr9_-_93405352 7.09 ENST00000375765.3
DIRAS family, GTP-binding RAS-like 2
chrX_-_13835147 6.72 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr12_-_6580094 6.68 ENST00000361716.3
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr12_-_90049828 6.62 ENST00000261173.2
ENST00000348959.3
ATPase, Ca++ transporting, plasma membrane 1
chr12_-_90049878 6.54 ENST00000359142.3
ATPase, Ca++ transporting, plasma membrane 1
chr1_+_84630645 6.28 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_67586465 6.25 ENST00000336483.5
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr11_-_47447970 6.16 ENST00000298852.3
ENST00000530912.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr12_+_79258444 6.03 ENST00000261205.4
synaptotagmin I
chr19_-_54618650 5.92 ENST00000391757.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr14_+_73563735 5.70 ENST00000532192.1
RNA binding motif protein 25
chr2_-_207024134 5.50 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr7_-_37026108 5.42 ENST00000396045.3
engulfment and cell motility 1
chr19_+_19626531 5.41 ENST00000507754.4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr2_-_207024233 5.39 ENST00000423725.1
ENST00000233190.6
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr5_-_111093167 5.38 ENST00000446294.2
ENST00000419114.2
neuronal regeneration related protein
chr19_-_54619006 5.30 ENST00000391759.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr3_-_98241358 5.02 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
claudin domain containing 1
chr11_-_62473706 4.99 ENST00000403550.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr8_-_81083890 4.89 ENST00000518937.1
tumor protein D52
chrX_+_65382433 4.86 ENST00000374727.3
hephaestin
chr6_+_158733692 4.84 ENST00000367094.2
ENST00000367097.3
tubby like protein 4
chr4_-_174320687 4.78 ENST00000296506.3
stimulator of chondrogenesis 1
chr8_-_22089845 4.70 ENST00000454243.2
phytanoyl-CoA 2-hydroxylase interacting protein
chr7_+_73106926 4.63 ENST00000453316.1
Williams Beuren syndrome chromosome region 22
chr17_-_29624343 4.62 ENST00000247271.4
oligodendrocyte myelin glycoprotein
chr11_-_47447767 4.58 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr5_+_140227048 4.55 ENST00000532602.1
protocadherin alpha 9
chr4_-_102268628 4.47 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
protein phosphatase 3, catalytic subunit, alpha isozyme
chr12_+_49621658 4.43 ENST00000541364.1
tubulin, alpha 1c
chr19_+_1440838 4.37 ENST00000594262.1
Uncharacterized protein
chr16_-_4852915 4.37 ENST00000322048.7
rogdi homolog (Drosophila)
chr4_-_102268484 4.34 ENST00000394853.4
protein phosphatase 3, catalytic subunit, alpha isozyme
chr16_+_22501658 4.29 ENST00000415833.2
nuclear pore complex interacting protein family, member B5
chr16_-_18466642 4.25 ENST00000541810.1
ENST00000531453.2
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr2_-_136678123 4.21 ENST00000422708.1
aspartyl-tRNA synthetase
chr8_-_18666360 4.21 ENST00000286485.8
pleckstrin and Sec7 domain containing 3
chr1_+_120254510 4.18 ENST00000369409.4
phosphoglycerate dehydrogenase
chr2_+_31456874 4.17 ENST00000541626.1
EH-domain containing 3
chr11_-_62473776 4.15 ENST00000278893.7
ENST00000407022.3
ENST00000421906.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr12_-_6579808 4.13 ENST00000535180.1
ENST00000400911.3
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr1_+_229440129 4.11 ENST00000366688.3
S-phase response (cyclin related)
chr11_-_102576537 3.89 ENST00000260229.4
matrix metallopeptidase 27
chr18_-_5396271 3.84 ENST00000579951.1
erythrocyte membrane protein band 4.1-like 3
chr9_-_21305312 3.79 ENST00000259555.4
interferon, alpha 5
chr2_-_176046391 3.76 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr3_-_18480260 3.71 ENST00000454909.2
SATB homeobox 1
chr14_-_21493123 3.70 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG family member 2
chr6_-_38670897 3.56 ENST00000373365.4
glyoxalase I
chr10_+_94352956 3.56 ENST00000260731.3
kinesin family member 11
chr5_-_176057365 3.53 ENST00000310112.3
synuclein, beta
chr6_-_8102714 3.51 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr3_-_33700933 3.49 ENST00000480013.1
cytoplasmic linker associated protein 2
chr15_+_66797627 3.48 ENST00000565627.1
ENST00000564179.1
zwilch kinetochore protein
chr4_-_48782259 3.40 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRY-like
chr17_+_17082842 3.39 ENST00000579361.1
myosin phosphatase Rho interacting protein
chr3_+_157827841 3.35 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
arginine/serine-rich coiled-coil 1
chr10_-_116444371 3.33 ENST00000533213.2
ENST00000369252.4
actin binding LIM protein 1
chr13_-_47471155 3.21 ENST00000543956.1
ENST00000542664.1
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr4_+_170581213 3.16 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr1_-_101360331 3.15 ENST00000416479.1
ENST00000370113.3
exostosin-like glycosyltransferase 2
chr11_+_19798964 3.06 ENST00000527559.2
neuron navigator 2
chrX_-_37706815 2.98 ENST00000378578.4
dynein, light chain, Tctex-type 3
chr8_+_26150628 2.97 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr16_+_16429787 2.93 ENST00000331436.4
ENST00000541593.1
Protein PKD1P1
chr16_-_66764119 2.92 ENST00000569320.1
dynein, cytoplasmic 1, light intermediate chain 2
chr15_+_66797455 2.92 ENST00000446801.2
zwilch kinetochore protein
chr17_-_4843316 2.91 ENST00000544061.2
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr5_-_20575959 2.84 ENST00000507958.1
cadherin 18, type 2
chr13_+_53030107 2.84 ENST00000490903.1
ENST00000480747.1
cytoskeleton associated protein 2
chr4_+_83956237 2.79 ENST00000264389.2
COP9 signalosome subunit 4
chr2_+_101591314 2.68 ENST00000450763.1
neuronal PAS domain protein 2
chr8_-_91095099 2.66 ENST00000265431.3
calbindin 1, 28kDa
chr11_-_117748138 2.66 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr12_-_30887948 2.65 ENST00000433722.2
caprin family member 2
chr9_+_108463234 2.64 ENST00000374688.1
transmembrane protein 38B
chr16_+_16472912 2.63 ENST00000530217.2
nuclear pore complex interacting protein family, member A7
chr4_+_83956312 2.62 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COP9 signalosome subunit 4
chr8_-_95220775 2.60 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
cadherin 17, LI cadherin (liver-intestine)
chr12_-_10573149 2.57 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
killer cell lectin-like receptor subfamily C, member 3
chr12_-_71551868 2.57 ENST00000247829.3
tetraspanin 8
chr19_+_54619125 2.55 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
pre-mRNA processing factor 31
chr8_+_104892639 2.53 ENST00000436393.2
regulating synaptic membrane exocytosis 2
chr11_+_27062502 2.51 ENST00000263182.3
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chrX_+_65384052 2.47 ENST00000336279.5
ENST00000458621.1
hephaestin
chrX_+_56590002 2.46 ENST00000338222.5
ubiquilin 2
chr1_-_246357029 2.45 ENST00000391836.2
SET and MYND domain containing 3
chr2_+_64069459 2.45 ENST00000445915.2
ENST00000475462.1
UDP-glucose pyrophosphorylase 2
chr16_+_14805546 2.43 ENST00000552140.1
nuclear pore complex interacting protein family, member A3
chr2_+_74056147 2.41 ENST00000394070.2
ENST00000536064.1
STAM binding protein
chr14_-_21492113 2.40 ENST00000554094.1
NDRG family member 2
chr2_+_64068844 2.38 ENST00000337130.5
UDP-glucose pyrophosphorylase 2
chr1_-_154909329 2.38 ENST00000368467.3
phosphomevalonate kinase
chr14_-_65439132 2.37 ENST00000533601.2
RAB15, member RAS oncogene family
chr14_+_53173890 2.36 ENST00000445930.2
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr11_+_121447469 2.35 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing
chr9_+_70856397 2.34 ENST00000360171.6
COBW domain containing 3
chr14_+_24540046 2.32 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
copine VI (neuronal)
chr22_-_30642782 2.32 ENST00000249075.3
leukemia inhibitory factor
chr1_+_65730385 2.29 ENST00000263441.7
ENST00000395325.3
DnaJ (Hsp40) homolog, subfamily C, member 6
chr18_+_32556892 2.29 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
microtubule-associated protein, RP/EB family, member 2
chr12_+_4758264 2.28 ENST00000266544.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr2_+_163175394 2.26 ENST00000446271.1
ENST00000429691.2
grancalcin, EF-hand calcium binding protein
chr6_-_99842041 2.25 ENST00000254759.3
ENST00000369242.1
coenzyme Q3 methyltransferase
chrX_+_77154935 2.22 ENST00000481445.1
cytochrome c oxidase subunit VIIb
chr10_-_62493223 2.22 ENST00000373827.2
ankyrin 3, node of Ranvier (ankyrin G)
chr17_-_4843206 2.20 ENST00000576951.1
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr14_-_21492251 2.20 ENST00000554398.1
NDRG family member 2
chrX_+_65382381 2.17 ENST00000519389.1
hephaestin
chr13_-_31736027 2.15 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
heat shock 105kDa/110kDa protein 1
chr6_+_30687978 2.15 ENST00000327892.8
ENST00000435534.1
tubulin, beta class I
chr16_-_15472151 2.13 ENST00000360151.4
ENST00000543801.1
nuclear pore complex interacting protein family, member A5
chr11_+_27062272 2.13 ENST00000529202.1
ENST00000533566.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_+_73771844 2.12 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
chr18_-_24443151 2.11 ENST00000440832.3
aquaporin 4
chr17_+_53344945 2.10 ENST00000575345.1
hepatic leukemia factor
chr3_+_130569429 2.09 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATPase, Ca++ transporting, type 2C, member 1
chr14_+_56127989 2.09 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr9_+_106856831 2.05 ENST00000303219.8
ENST00000374787.3
structural maintenance of chromosomes 2
chr9_-_130829588 2.01 ENST00000373078.4
nuclear apoptosis inducing factor 1
chr12_-_71148357 2.00 ENST00000378778.1
protein tyrosine phosphatase, receptor type, R
chr17_+_48823975 1.97 ENST00000513969.1
ENST00000503728.1
LUC7-like 3 (S. cerevisiae)
chr3_+_35722487 1.96 ENST00000441454.1
cAMP-regulated phosphoprotein, 21kDa
chr8_-_66546439 1.96 ENST00000276569.3
armadillo repeat containing 1
chr15_-_55489097 1.94 ENST00000260443.4
ribosomal L24 domain containing 1
chr16_-_30441293 1.94 ENST00000565758.1
ENST00000567983.1
ENST00000319285.4
dCTP pyrophosphatase 1
chr11_+_27062860 1.93 ENST00000528583.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chrX_-_102943022 1.91 ENST00000433176.2
mortality factor 4 like 2
chr13_+_53029564 1.90 ENST00000468284.1
ENST00000378034.3
ENST00000258607.5
ENST00000378037.5
cytoskeleton associated protein 2
chr7_+_141811539 1.90 ENST00000550469.2
ENST00000477922.3
Putative inactive maltase-glucoamylase-like protein LOC93432
chr11_-_60674037 1.89 ENST00000541371.1
ENST00000227524.4
pre-mRNA processing factor 19
chrX_-_148571884 1.88 ENST00000537071.1
iduronate 2-sulfatase
chr20_+_36405665 1.88 ENST00000373469.1
catenin, beta like 1
chr16_+_14844670 1.88 ENST00000553201.1
nuclear pore complex interacting protein family, member A2
chrX_+_65384182 1.87 ENST00000441993.2
ENST00000419594.1
hephaestin
chr17_-_38545799 1.87 ENST00000577541.1
topoisomerase (DNA) II alpha 170kDa
chr5_+_135496675 1.87 ENST00000507637.1
SMAD family member 5
chr12_-_118796910 1.86 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr19_+_56152262 1.83 ENST00000325333.5
ENST00000590190.1
zinc finger protein 580
chr4_-_87281224 1.83 ENST00000395169.3
ENST00000395161.2
mitogen-activated protein kinase 10
chr16_+_57653989 1.82 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
G protein-coupled receptor 56
chr1_-_226926864 1.80 ENST00000429204.1
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr4_+_86396265 1.79 ENST00000395184.1
Rho GTPase activating protein 24
chr11_-_35441524 1.78 ENST00000395750.1
ENST00000449068.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr13_-_31736478 1.77 ENST00000445273.2
heat shock 105kDa/110kDa protein 1
chr3_-_39321512 1.75 ENST00000399220.2
chemokine (C-X3-C motif) receptor 1
chr1_+_156163880 1.74 ENST00000359511.4
ENST00000423538.2
solute carrier family 25, member 44
chr10_+_47894023 1.74 ENST00000358474.5
family with sequence similarity 21, member B
chrX_-_135962876 1.73 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RNA binding motif protein, X-linked
chr18_+_19192228 1.73 ENST00000300413.5
ENST00000579618.1
ENST00000582475.1
small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr1_-_68962805 1.72 ENST00000370966.5
DEP domain containing 1
chr11_+_27076764 1.72 ENST00000525090.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr14_+_56078695 1.72 ENST00000416613.1
kinectin 1 (kinesin receptor)
chr1_+_66797687 1.71 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
phosphodiesterase 4B, cAMP-specific
chr4_-_164534657 1.70 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr5_+_167913450 1.69 ENST00000231572.3
ENST00000538719.1
arginyl-tRNA synthetase
chr11_-_35440796 1.67 ENST00000278379.3
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_+_170440844 1.66 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
peptidylprolyl isomerase G (cyclophilin G)
chr7_-_36634181 1.66 ENST00000538464.1
acyloxyacyl hydrolase (neutrophil)
chr16_+_57653854 1.64 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
G protein-coupled receptor 56
chr2_-_166930131 1.63 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
sodium channel, voltage-gated, type I, alpha subunit
chr11_+_76745385 1.61 ENST00000533140.1
ENST00000354301.5
ENST00000528622.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr12_-_100486668 1.59 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1 binding protein 1-like
chr12_+_1800179 1.59 ENST00000357103.4
adiponectin receptor 2
chr2_+_173600514 1.58 ENST00000264111.6
Rap guanine nucleotide exchange factor (GEF) 4
chr1_+_155278539 1.57 ENST00000447866.1
farnesyl diphosphate synthase
chr17_+_58018269 1.52 ENST00000591035.1
Uncharacterized protein
chrX_-_100604184 1.52 ENST00000372902.3
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr10_-_50970322 1.52 ENST00000374103.4
oxoglutarate dehydrogenase-like
chr5_+_140749803 1.51 ENST00000576222.1
protocadherin gamma subfamily B, 3
chr16_-_21431078 1.48 ENST00000458643.2
nuclear pore complex interacting protein family, member B3
chr12_-_48099773 1.48 ENST00000432584.3
ENST00000005386.3
RNA polymerase II associated protein 3
chr12_+_19358228 1.48 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr19_-_10420459 1.48 ENST00000403352.1
ENST00000403903.3
zinc finger, GATA-like protein 1
chr9_-_21202204 1.48 ENST00000239347.3
interferon, alpha 7
chr2_-_209010874 1.47 ENST00000260988.4
crystallin, gamma B
chr22_+_41956767 1.46 ENST00000306149.7
cold shock domain containing C2, RNA binding
chr1_-_149900122 1.45 ENST00000271628.8
splicing factor 3b, subunit 4, 49kDa
chr13_-_30424821 1.45 ENST00000380680.4
ubiquitin-like 3
chr6_-_131321863 1.44 ENST00000528282.1
erythrocyte membrane protein band 4.1-like 2
chr6_+_12958137 1.43 ENST00000457702.2
ENST00000379345.2
phosphatase and actin regulator 1
chr2_-_228497888 1.41 ENST00000264387.4
ENST00000409066.1
chromosome 2 open reading frame 83
chr2_+_220143989 1.40 ENST00000336576.5
DnaJ (Hsp40) homolog, subfamily B, member 2
chr8_-_117886955 1.39 ENST00000297338.2
RAD21 homolog (S. pombe)

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD11_HOXA11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.8 GO:0007412 axon target recognition(GO:0007412)
3.0 15.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
2.9 8.8 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
2.6 13.2 GO:1990034 calcium ion export from cell(GO:1990034)
2.1 16.8 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
2.0 6.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
2.0 2.0 GO:0030001 metal ion transport(GO:0030001)
1.6 12.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.4 4.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
1.4 4.2 GO:0006566 threonine metabolic process(GO:0006566)
1.3 20.9 GO:0000338 protein deneddylation(GO:0000338)
1.3 6.3 GO:0097338 response to clozapine(GO:0097338)
1.0 4.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.9 8.3 GO:0003190 atrioventricular valve formation(GO:0003190)
0.9 4.4 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.9 5.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.8 2.5 GO:0046098 guanine metabolic process(GO:0046098)
0.8 2.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.8 7.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.8 3.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.8 2.4 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.8 9.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.8 7.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.8 3.8 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.8 3.1 GO:0021564 vagus nerve development(GO:0021564)
0.7 3.6 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.7 6.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.7 2.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.6 1.9 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.6 10.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.6 3.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.6 1.3 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.6 2.5 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.6 5.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.6 2.9 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.6 4.7 GO:1903750 negative regulation of establishment of protein localization to mitochondrion(GO:1903748) regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.6 1.7 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.6 2.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.6 2.3 GO:0060708 histone H3-K27 acetylation(GO:0043974) leukemia inhibitory factor signaling pathway(GO:0048861) spongiotrophoblast differentiation(GO:0060708) regulation of histone H3-K27 acetylation(GO:1901674)
0.6 10.7 GO:0035493 SNARE complex assembly(GO:0035493)
0.6 1.7 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.5 3.8 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.5 8.3 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.5 2.6 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.5 1.9 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.5 12.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.5 1.4 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.5 1.8 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.5 2.7 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.4 6.2 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.4 11.4 GO:0006825 copper ion transport(GO:0006825)
0.4 3.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.4 2.6 GO:0048254 snoRNA localization(GO:0048254)
0.4 2.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.4 1.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.4 1.9 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.4 2.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.4 2.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.4 1.9 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.4 1.5 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.4 21.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.4 1.8 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.4 8.5 GO:0034389 lipid particle organization(GO:0034389)
0.3 2.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.3 1.0 GO:0014807 regulation of somitogenesis(GO:0014807)
0.3 4.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.3 1.4 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.3 1.0 GO:0050923 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.3 1.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.3 1.9 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.3 1.9 GO:0001880 Mullerian duct regression(GO:0001880)
0.3 1.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.3 5.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.3 1.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.3 3.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.3 2.5 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.3 1.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.3 1.9 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.3 1.3 GO:0006574 valine catabolic process(GO:0006574)
0.3 2.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 3.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 2.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 0.7 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.2 1.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.2 1.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 4.0 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.2 1.3 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.2 4.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 0.8 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.2 0.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 2.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 2.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.2 1.0 GO:0035617 stress granule disassembly(GO:0035617)
0.2 1.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 0.8 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.6 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.2 0.8 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.2 0.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 0.6 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.2 3.4 GO:0090527 actin filament reorganization(GO:0090527)
0.2 3.6 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.2 1.9 GO:0030263 resolution of meiotic recombination intermediates(GO:0000712) apoptotic chromosome condensation(GO:0030263) regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.2 0.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 0.9 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.2 4.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 2.7 GO:0051775 response to redox state(GO:0051775)
0.2 12.5 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.2 1.0 GO:0031642 negative regulation of myelination(GO:0031642)
0.2 0.8 GO:0033344 cholesterol efflux(GO:0033344)
0.2 1.7 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.2 3.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 2.5 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 1.5 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.6 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 1.2 GO:0010265 SCF complex assembly(GO:0010265)
0.1 5.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.3 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.1 2.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.6 GO:0071233 cellular response to leucine(GO:0071233)
0.1 1.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 1.5 GO:0061458 reproductive system development(GO:0061458)
0.1 1.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.7 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.1 3.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 2.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.3 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 1.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.9 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 1.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.7 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 4.5 GO:0061512 protein localization to cilium(GO:0061512)
0.1 1.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.6 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.9 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 2.5 GO:0006833 water transport(GO:0006833)
0.1 2.4 GO:0014904 myotube cell development(GO:0014904)
0.1 1.7 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.1 2.7 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 1.0 GO:0019321 pentose metabolic process(GO:0019321)
0.1 0.7 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 2.5 GO:0051642 centrosome localization(GO:0051642)
0.1 0.6 GO:0035799 ureter maturation(GO:0035799)
0.1 2.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.1 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.1 0.7 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.7 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 3.6 GO:0042417 dopamine metabolic process(GO:0042417)
0.1 1.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.0 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 0.6 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 0.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 2.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.6 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.8 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.1 1.4 GO:0017004 cytochrome complex assembly(GO:0017004)
0.1 4.6 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.1 0.4 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.1 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.5 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 2.7 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 1.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 6.6 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 1.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.3 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 8.2 GO:0051028 mRNA transport(GO:0051028)
0.0 1.3 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.4 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 6.1 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.8 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.3 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 2.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0032900 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) regulation of neurotrophin production(GO:0032899) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911) negative regulation of receptor catabolic process(GO:2000645)
0.0 0.7 GO:0051607 defense response to virus(GO:0051607)
0.0 0.2 GO:0032328 alanine transport(GO:0032328)
0.0 3.8 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.2 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.6 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 9.1 GO:0006310 DNA recombination(GO:0006310)
0.0 6.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 1.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 3.2 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.8 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.7 GO:0006012 galactose metabolic process(GO:0006012)
0.0 2.3 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.0 1.3 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.4 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 2.9 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.6 GO:0045143 homologous chromosome segregation(GO:0045143)
0.0 1.8 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.3 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 2.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0043304 regulation of myeloid leukocyte mediated immunity(GO:0002886) regulation of mast cell activation(GO:0033003) regulation of mast cell activation involved in immune response(GO:0033006) regulation of leukocyte degranulation(GO:0043300) regulation of mast cell degranulation(GO:0043304)
0.0 0.9 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 1.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.2 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.5 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.4 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.5 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.4 GO:0010458 exit from mitosis(GO:0010458)
0.0 1.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.1 GO:1905065 protein-pyridoxal-5-phosphate linkage(GO:0018352) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.2 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.2 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 1.1 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.3 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.2 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.1 GO:0002003 angiotensin maturation(GO:0002003)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 18.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
2.2 15.2 GO:0033269 internode region of axon(GO:0033269)
1.6 6.4 GO:1990423 RZZ complex(GO:1990423)
1.6 6.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
1.2 6.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.1 13.1 GO:0031595 nuclear proteasome complex(GO:0031595)
1.0 8.8 GO:0005955 calcineurin complex(GO:0005955)
0.8 4.2 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.6 3.9 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.6 1.9 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.6 13.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.6 11.6 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.5 2.5 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.5 3.2 GO:0070852 cell body fiber(GO:0070852)
0.5 9.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.5 5.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.4 23.4 GO:0008180 COP9 signalosome(GO:0008180)
0.4 9.3 GO:0044295 axonal growth cone(GO:0044295)
0.4 1.9 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.3 3.5 GO:0045180 basal cortex(GO:0045180)
0.3 1.4 GO:0000798 nuclear cohesin complex(GO:0000798)
0.3 1.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.3 6.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 5.2 GO:0043194 axon initial segment(GO:0043194)
0.3 4.8 GO:0033270 paranode region of axon(GO:0033270)
0.3 1.5 GO:0097255 R2TP complex(GO:0097255)
0.3 4.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 3.1 GO:0005614 interstitial matrix(GO:0005614)
0.3 4.3 GO:0005687 U4 snRNP(GO:0005687)
0.3 11.8 GO:1904115 axon cytoplasm(GO:1904115)
0.2 1.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 1.9 GO:0016013 syntrophin complex(GO:0016013)
0.2 3.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 5.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 2.0 GO:0000796 condensin complex(GO:0000796)
0.2 19.5 GO:0042734 presynaptic membrane(GO:0042734)
0.2 8.7 GO:0031201 SNARE complex(GO:0031201)
0.2 1.2 GO:0030870 Mre11 complex(GO:0030870)
0.2 4.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.2 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.7 GO:0036128 CatSper complex(GO:0036128)
0.1 3.3 GO:0030673 axolemma(GO:0030673)
0.1 8.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 2.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 1.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 1.9 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.6 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 2.0 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 1.1 GO:0061574 ASAP complex(GO:0061574)
0.1 0.9 GO:0035253 ciliary rootlet(GO:0035253)
0.1 7.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 16.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 4.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 3.6 GO:0005871 kinesin complex(GO:0005871)
0.1 0.8 GO:0034709 methylosome(GO:0034709)
0.1 1.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.7 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.2 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 9.6 GO:0005643 nuclear pore(GO:0005643)
0.1 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.7 GO:0032982 myosin filament(GO:0032982)
0.1 11.7 GO:0030427 site of polarized growth(GO:0030427)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 2.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 1.2 GO:0000145 exocyst(GO:0000145)
0.1 1.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 7.7 GO:0044306 neuron projection terminus(GO:0044306)
0.1 1.4 GO:0031143 pseudopodium(GO:0031143)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.2 GO:0071564 npBAF complex(GO:0071564)
0.1 17.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 7.4 GO:0031901 early endosome membrane(GO:0031901)
0.1 2.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 2.3 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.9 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 2.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 3.4 GO:0005925 focal adhesion(GO:0005925)
0.0 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 12.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 4.1 GO:0043209 myelin sheath(GO:0043209)
0.0 10.8 GO:0016607 nuclear speck(GO:0016607)
0.0 1.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.7 GO:0016234 inclusion body(GO:0016234)
0.0 2.7 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 24.9 GO:0005739 mitochondrion(GO:0005739)
0.0 3.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 5.5 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.6 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 2.8 GO:0005874 microtubule(GO:0005874)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.7 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 1.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0070069 cytochrome complex(GO:0070069)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 11.8 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
2.1 8.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
2.0 21.9 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.6 4.8 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
1.3 15.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.3 11.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.2 6.0 GO:0030348 syntaxin-3 binding(GO:0030348)
1.2 13.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
1.1 16.8 GO:0097109 neuroligin family protein binding(GO:0097109)
1.0 5.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.9 8.8 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.9 17.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.8 4.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.8 4.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.8 2.5 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.8 2.4 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.8 6.2 GO:0043559 insulin binding(GO:0043559)
0.7 1.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.7 2.6 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.6 1.9 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.6 3.2 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.6 5.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.6 1.9 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.6 2.9 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.6 1.7 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.6 1.7 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.5 5.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.5 1.6 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.5 3.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.5 15.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.5 1.4 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.4 5.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.4 6.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 4.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 1.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.4 3.0 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.4 2.6 GO:0030621 U4 snRNA binding(GO:0030621)
0.3 1.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 1.4 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.3 1.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.3 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 1.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 1.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.3 1.8 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 1.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.3 1.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.3 1.4 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.3 2.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.3 0.8 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.3 3.5 GO:1903136 cuprous ion binding(GO:1903136)
0.3 1.0 GO:0099609 microtubule lateral binding(GO:0099609)
0.2 3.0 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 1.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 0.7 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.2 0.7 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.2 0.7 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2 5.4 GO:0002162 dystroglycan binding(GO:0002162)
0.2 3.0 GO:0048156 tau protein binding(GO:0048156)
0.2 2.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 1.2 GO:0051870 methotrexate binding(GO:0051870)
0.2 0.8 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 9.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 2.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.2 8.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 0.9 GO:0051373 FATZ binding(GO:0051373)
0.2 0.6 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.2 3.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 1.7 GO:1990446 U1 snRNP binding(GO:1990446)
0.2 4.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 2.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 2.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 0.9 GO:0005499 vitamin D binding(GO:0005499)
0.2 2.6 GO:0015250 water channel activity(GO:0015250)
0.2 1.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.4 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 2.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.4 GO:0042731 PH domain binding(GO:0042731)
0.1 2.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 3.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 3.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.8 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 1.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 2.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.9 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.9 GO:0015116 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.1 0.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.9 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 2.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 2.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 2.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 1.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 2.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 4.0 GO:0030507 spectrin binding(GO:0030507)
0.1 2.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.2 GO:0031386 protein tag(GO:0031386)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 1.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 1.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 3.7 GO:0030552 cAMP binding(GO:0030552)
0.1 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 2.2 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 1.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 3.7 GO:0019894 kinesin binding(GO:0019894)
0.1 1.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.2 GO:0097602 cullin family protein binding(GO:0097602)
0.1 2.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 1.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 3.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.9 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 1.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 2.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 2.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 2.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 2.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.2 GO:0004819 glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.1 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 2.0 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 0.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.6 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 8.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 1.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 2.4 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.4 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.9 GO:0030275 LRR domain binding(GO:0030275)
0.0 2.3 GO:0005524 ATP binding(GO:0005524) adenyl nucleotide binding(GO:0030554) adenyl ribonucleotide binding(GO:0032559)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 1.9 GO:0051536 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0 1.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 3.5 GO:0003774 motor activity(GO:0003774)
0.0 2.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 9.1 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.6 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.0 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 3.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 4.9 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 9.5 GO:0005525 GTP binding(GO:0005525)
0.0 0.8 GO:0008289 lipid binding(GO:0008289)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.6 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0005452 inorganic anion exchanger activity(GO:0005452) sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 1.2 GO:0004386 helicase activity(GO:0004386)
0.0 0.5 GO:0032947 protein complex scaffold(GO:0032947)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.2 PID IL5 PATHWAY IL5-mediated signaling events
0.2 6.0 PID IL3 PATHWAY IL3-mediated signaling events
0.2 8.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 8.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 1.8 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 10.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 5.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 1.9 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 12.3 PID CMYB PATHWAY C-MYB transcription factor network
0.1 4.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 6.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 1.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 3.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 6.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 3.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 3.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.9 PID AURORA B PATHWAY Aurora B signaling
0.0 2.5 PID E2F PATHWAY E2F transcription factor network
0.0 1.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 15.5 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.5 11.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 27.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 6.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 16.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.3 9.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 6.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 6.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 13.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 2.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 4.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 4.6 REACTOME KINESINS Genes involved in Kinesins
0.2 5.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 4.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 10.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 5.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 3.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.2 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1 5.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 2.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 1.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 2.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 6.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 7.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.3 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.1 1.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 3.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 4.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 4.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 2.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 3.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 3.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.8 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 1.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.9 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo