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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HSF1

Z-value: 1.22

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Transcription factors associated with HSF1

Gene Symbol Gene ID Gene Info
ENSG00000185122.6 heat shock transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF1hg19_v2_chr8_+_145515263_145515299-0.127.8e-02Click!

Activity profile of HSF1 motif

Sorted Z-values of HSF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_33041378 41.32 ENST00000428995.1
major histocompatibility complex, class II, DP alpha 1
chr19_+_1065922 26.17 ENST00000539243.2
histocompatibility (minor) HA-1
chr1_+_111415757 22.73 ENST00000429072.2
ENST00000271324.5
CD53 molecule
chr4_-_84030996 21.37 ENST00000411416.2
placenta-specific 8
chr2_-_89513402 18.91 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr6_-_32557610 18.30 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr1_-_153363452 18.04 ENST00000368732.1
ENST00000368733.3
S100 calcium binding protein A8
chr6_-_32498046 17.51 ENST00000374975.3
major histocompatibility complex, class II, DR beta 5
chr6_+_32605195 17.31 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr14_-_106092403 17.14 ENST00000390543.2
immunoglobulin heavy constant gamma 4 (G4m marker)
chr5_+_118690466 13.11 ENST00000503646.1
tumor necrosis factor, alpha-induced protein 8
chr7_+_150264365 13.05 ENST00000255945.2
ENST00000461940.1
GTPase, IMAP family member 4
chr16_+_85942594 12.20 ENST00000566369.1
interferon regulatory factor 8
chr14_-_106926724 11.80 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr6_+_32811885 11.76 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr3_-_46506563 11.73 ENST00000231751.4
lactotransferrin
chr6_-_41909561 11.65 ENST00000372991.4
cyclin D3
chr3_-_46506358 11.52 ENST00000417439.1
ENST00000431944.1
lactotransferrin
chr6_-_41909466 11.45 ENST00000414200.2
cyclin D3
chr6_+_32605134 11.11 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
major histocompatibility complex, class II, DQ alpha 1
chr22_-_17680472 10.95 ENST00000330232.4
cat eye syndrome chromosome region, candidate 1
chr1_+_161494036 10.89 ENST00000309758.4
heat shock 70kDa protein 6 (HSP70B')
chr14_-_106573756 10.80 ENST00000390601.2
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr2_-_201729284 10.69 ENST00000434813.2
CDC-like kinase 1
chr6_-_41909191 10.21 ENST00000512426.1
ENST00000372987.4
cyclin D3
chr19_-_54876558 10.21 ENST00000391742.2
ENST00000434277.2
leukocyte-associated immunoglobulin-like receptor 1
chr6_-_32812420 10.16 ENST00000374881.2
proteasome (prosome, macropain) subunit, beta type, 8
chr2_+_85922491 9.86 ENST00000526018.1
granulysin
chr6_+_29910301 9.77 ENST00000376809.5
ENST00000376802.2
major histocompatibility complex, class I, A
chr19_-_2051223 9.34 ENST00000309340.7
ENST00000589534.1
ENST00000250896.3
ENST00000589509.1
MAP kinase interacting serine/threonine kinase 2
chr6_-_32811771 9.08 ENST00000395339.3
ENST00000374882.3
proteasome (prosome, macropain) subunit, beta type, 8
chr6_+_35265586 8.63 ENST00000542066.1
ENST00000316637.5
differentially expressed in FDCP 6 homolog (mouse)
chr22_-_26961328 8.30 ENST00000398110.2
tyrosylprotein sulfotransferase 2
chr7_+_150434430 8.07 ENST00000358647.3
GTPase, IMAP family member 5
chr7_-_139763521 8.03 ENST00000263549.3
poly (ADP-ribose) polymerase family, member 12
chr15_-_55581954 7.88 ENST00000336787.1
RAB27A, member RAS oncogene family
chr5_-_171615315 7.28 ENST00000176763.5
serine/threonine kinase 10
chr14_-_106552755 7.23 ENST00000390600.2
immunoglobulin heavy variable 3-9
chr17_-_39661849 7.14 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
keratin 13
chr11_+_809961 7.13 ENST00000530797.1
ribosomal protein, large, P2
chr1_+_212782012 7.03 ENST00000341491.4
ENST00000366985.1
activating transcription factor 3
chr2_+_61404624 7.00 ENST00000394457.3
AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)
chr14_+_23012122 6.98 ENST00000390534.1
T cell receptor alpha joining 3
chr11_-_102323489 6.96 ENST00000361236.3
transmembrane protein 123
chr1_-_17215868 6.81 ENST00000422124.1
RP11-108M9.4
chr5_-_169694286 6.78 ENST00000521416.1
ENST00000520344.1
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_-_17216109 6.72 ENST00000416869.1
RP11-108M9.4
chr19_-_54876414 6.60 ENST00000474878.1
ENST00000348231.4
leukocyte-associated immunoglobulin-like receptor 1
chr22_-_26986045 6.58 ENST00000442495.1
ENST00000440953.1
ENST00000450022.1
ENST00000338754.4
tyrosylprotein sulfotransferase 2
chr12_+_10460549 6.58 ENST00000543420.1
ENST00000543777.1
killer cell lectin-like receptor subfamily D, member 1
chr12_-_57505121 6.51 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
signal transducer and activator of transcription 6, interleukin-4 induced
chr6_+_89674246 6.49 ENST00000369474.1
Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741
chr6_-_167369612 6.49 ENST00000507747.1
RP11-514O12.4
chr5_-_175964366 6.43 ENST00000274811.4
ring finger protein 44
chr6_+_31783291 6.33 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr18_-_19284724 6.33 ENST00000580981.1
ENST00000289119.2
abhydrolase domain containing 3
chr11_-_104840093 6.32 ENST00000417440.2
ENST00000444739.2
caspase 4, apoptosis-related cysteine peptidase
chr16_+_68119764 6.27 ENST00000570212.1
ENST00000562926.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr11_-_64512273 6.24 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr1_+_6105974 6.06 ENST00000378083.3
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr1_-_20306909 6.00 ENST00000375111.3
ENST00000400520.3
phospholipase A2, group IIA (platelets, synovial fluid)
chr22_-_36556821 5.91 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
apolipoprotein L, 3
chr5_+_156696362 5.89 ENST00000377576.3
cytoplasmic FMR1 interacting protein 2
chr19_+_47813110 5.85 ENST00000355085.3
complement component 5a receptor 1
chr14_-_25045446 5.82 ENST00000216336.2
cathepsin G
chr22_-_29196546 5.81 ENST00000403532.3
ENST00000216037.6
X-box binding protein 1
chr17_-_76123101 5.69 ENST00000392467.3
transmembrane channel-like 6
chr11_-_104905840 5.67 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr16_+_222846 5.63 ENST00000251595.6
ENST00000397806.1
hemoglobin, alpha 2
chr19_+_13842559 5.53 ENST00000586600.1
coiled-coil domain containing 130
chr12_+_6898638 5.45 ENST00000011653.4
CD4 molecule
chr21_+_42733870 5.43 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
myxovirus (influenza virus) resistance 2 (mouse)
chr14_-_106725723 5.37 ENST00000390609.2
immunoglobulin heavy variable 3-23
chr18_+_57567180 5.26 ENST00000316660.6
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr15_+_81589254 5.26 ENST00000394652.2
interleukin 16
chr14_-_106668095 5.22 ENST00000390606.2
immunoglobulin heavy variable 3-20
chr14_-_107049312 5.16 ENST00000390627.2
immunoglobulin heavy variable 3-53
chr4_-_25865159 5.01 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr13_-_49018789 4.98 ENST00000378434.4
lysophosphatidic acid receptor 6
chr11_+_117063295 4.96 ENST00000525478.1
ENST00000532062.1
SID1 transmembrane family, member 2
chr12_+_51632508 4.95 ENST00000449723.3
DAZ associated protein 2
chr12_+_10460417 4.89 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
killer cell lectin-like receptor subfamily D, member 1
chr1_+_212738676 4.70 ENST00000366981.4
ENST00000366987.2
activating transcription factor 3
chr7_+_130020932 4.67 ENST00000484324.1
carboxypeptidase A1 (pancreatic)
chr1_-_236030216 4.62 ENST00000389794.3
ENST00000389793.2
lysosomal trafficking regulator
chr20_-_4795747 4.61 ENST00000379376.2
Ras association (RalGDS/AF-6) domain family member 2
chr22_+_37309662 4.58 ENST00000403662.3
ENST00000262825.5
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr7_+_150065278 4.56 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
replication initiator 1
chr1_-_225615599 4.51 ENST00000421383.1
ENST00000272163.4
lamin B receptor
chr3_+_42947600 4.49 ENST00000328199.6
ENST00000541208.1
zinc finger protein 662
chr11_+_10471836 4.47 ENST00000444303.2
adenosine monophosphate deaminase 3
chrX_-_73072534 4.45 ENST00000429829.1
X inactive specific transcript (non-protein coding)
chr21_+_35445827 4.40 ENST00000608209.1
ENST00000381151.3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr16_+_1583567 4.37 ENST00000566264.1
transmembrane protein 204
chr16_+_28943260 4.33 ENST00000538922.1
ENST00000324662.3
ENST00000567541.1
CD19 molecule
chr5_+_40909354 4.28 ENST00000313164.9
complement component 7
chr10_+_114133773 4.27 ENST00000354655.4
acyl-CoA synthetase long-chain family member 5
chrX_-_47518498 4.20 ENST00000335890.2
ubiquitously-expressed, prefoldin-like chaperone
chr20_-_44455976 4.18 ENST00000372555.3
troponin C type 2 (fast)
chr2_+_219247021 4.16 ENST00000539932.1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr6_+_31795506 4.16 ENST00000375650.3
heat shock 70kDa protein 1B
chrX_+_64887512 4.16 ENST00000360270.5
moesin
chr11_+_65190245 4.13 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr17_-_56350797 4.12 ENST00000577220.1
myeloperoxidase
chr19_+_55014085 4.08 ENST00000351841.2
leukocyte-associated immunoglobulin-like receptor 2
chr7_+_102715315 4.06 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
armadillo repeat containing 10
chrX_+_13752832 4.04 ENST00000380550.3
ENST00000398395.3
ENST00000340096.6
ENST00000380567.1
oral-facial-digital syndrome 1
chr21_-_43735446 3.98 ENST00000398431.2
trefoil factor 3 (intestinal)
chr2_+_102624977 3.96 ENST00000441002.1
interleukin 1 receptor, type II
chr11_-_1785139 3.94 ENST00000236671.2
cathepsin D
chr13_-_79979919 3.94 ENST00000267229.7
RNA binding motif protein 26
chr19_-_14629224 3.92 ENST00000254322.2
DnaJ (Hsp40) homolog, subfamily B, member 1
chr16_-_15180257 3.92 ENST00000540462.1
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr21_-_34144157 3.90 ENST00000331923.4
PAX3 and PAX7 binding protein 1
chr16_+_28996572 3.85 ENST00000360872.5
ENST00000566177.1
ENST00000354453.4
linker for activation of T cells
chr1_-_225616515 3.73 ENST00000338179.2
ENST00000425080.1
lamin B receptor
chr1_+_22307592 3.72 ENST00000400277.2
chymotrypsin-like elastase family, member 3B
chr14_-_106518922 3.69 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr12_-_52911718 3.68 ENST00000548409.1
keratin 5
chr17_-_3595181 3.63 ENST00000552050.1
purinergic receptor P2X, ligand-gated ion channel, 5
chr16_-_20339123 3.62 ENST00000381360.5
glycoprotein 2 (zymogen granule membrane)
chr13_-_79979952 3.62 ENST00000438724.1
RNA binding motif protein 26
chr16_-_20338748 3.61 ENST00000575582.1
ENST00000341642.5
ENST00000381362.4
ENST00000572347.1
ENST00000572478.1
ENST00000302555.5
glycoprotein 2 (zymogen granule membrane)
chr20_+_46130671 3.58 ENST00000371998.3
ENST00000371997.3
nuclear receptor coactivator 3
chr3_-_48936272 3.57 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chrX_+_15767971 3.57 ENST00000479740.1
ENST00000454127.2
carbonic anhydrase VB, mitochondrial
chr7_+_80275752 3.56 ENST00000419819.2
CD36 molecule (thrombospondin receptor)
chr15_-_55563072 3.55 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A, member RAS oncogene family
chrX_-_154563889 3.54 ENST00000369449.2
ENST00000321926.4
chloride intracellular channel 2
chr9_-_97402531 3.54 ENST00000415431.1
fructose-1,6-bisphosphatase 1
chr17_+_8339189 3.53 ENST00000585098.1
ENST00000380025.4
ENST00000402554.3
ENST00000584866.1
ENST00000582490.1
nudE neurodevelopment protein 1-like 1
chr7_+_114562172 3.53 ENST00000393486.1
ENST00000257724.3
MyoD family inhibitor domain containing
chr8_-_61880248 3.49 ENST00000525556.1
AC022182.3
chr19_+_55014013 3.47 ENST00000301202.2
leukocyte-associated immunoglobulin-like receptor 2
chrX_-_230884 3.46 ENST00000400701.3
ENST00000326153.4
GTP binding protein 6 (putative)
chr8_-_101321584 3.46 ENST00000523167.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr13_-_79980315 3.44 ENST00000438737.2
RNA binding motif protein 26
chr4_-_48136217 3.44 ENST00000264316.4
TXK tyrosine kinase
chr6_-_131949305 3.35 ENST00000368053.4
ENST00000354577.4
ENST00000403834.3
ENST00000540546.1
ENST00000368068.3
ENST00000368060.3
mediator complex subunit 23
chr2_-_225811747 3.34 ENST00000409592.3
dedicator of cytokinesis 10
chr3_-_150920979 3.34 ENST00000309180.5
ENST00000480322.1
G protein-coupled receptor 171
chr7_-_99573640 3.34 ENST00000411734.1
alpha-2-glycoprotein 1, zinc-binding
chr1_+_67773044 3.33 ENST00000262345.1
ENST00000371000.1
interleukin 12 receptor, beta 2
chr18_+_9136758 3.31 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ankyrin repeat domain 12
chr16_-_79634595 3.27 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr7_-_99573677 3.22 ENST00000292401.4
alpha-2-glycoprotein 1, zinc-binding
chr1_-_160832642 3.21 ENST00000368034.4
CD244 molecule, natural killer cell receptor 2B4
chr3_+_101443476 3.20 ENST00000327230.4
ENST00000494050.1
centrosomal protein 97kDa
chr20_-_23731569 3.20 ENST00000304749.2
cystatin SN
chr8_+_142402089 3.19 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
protein tyrosine phosphatase type IVA, member 3
chr3_-_187454281 3.17 ENST00000232014.4
B-cell CLL/lymphoma 6
chr11_+_46354455 3.16 ENST00000343674.6
diacylglycerol kinase, zeta
chr12_-_108154925 3.15 ENST00000228437.5
PR domain containing 4
chrY_-_180884 3.15 ENSTR0000400701.3
ENSTR0000326153.4
GTP binding protein 6 (putative)
chrX_+_108779870 3.12 ENST00000372107.1
nuclear transport factor 2-like export factor 2
chr9_+_123970052 3.11 ENST00000373823.3
gelsolin
chr9_+_140513438 3.11 ENST00000462484.1
ENST00000334856.6
ENST00000460843.1
euchromatic histone-lysine N-methyltransferase 1
chr13_+_31191920 3.10 ENST00000255304.4
ubiquitin specific peptidase like 1
chr14_-_106586656 3.07 ENST00000390602.2
immunoglobulin heavy variable 3-13
chr18_+_13611763 3.07 ENST00000585931.1
low density lipoprotein receptor class A domain containing 4
chrX_-_47518527 3.03 ENST00000333119.3
ubiquitously-expressed, prefoldin-like chaperone
chr10_-_125851961 3.01 ENST00000346248.5
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr2_-_191878874 2.99 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
signal transducer and activator of transcription 1, 91kDa
chr16_+_28996416 2.98 ENST00000395456.2
ENST00000454369.2
linker for activation of T cells
chr22_+_41253080 2.98 ENST00000541156.1
ENST00000414396.1
ENST00000357137.4
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr2_+_58655461 2.98 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
long intergenic non-protein coding RNA 1122
chr12_-_123011536 2.94 ENST00000331738.7
ENST00000354654.2
arginine/serine-rich coiled-coil 2
chr8_+_38677850 2.92 ENST00000518809.1
ENST00000520611.1
transforming, acidic coiled-coil containing protein 1
chr7_+_80275621 2.91 ENST00000426978.1
ENST00000432207.1
CD36 molecule (thrombospondin receptor)
chr6_-_32784687 2.90 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr12_+_51632600 2.88 ENST00000549555.1
ENST00000439799.2
ENST00000425012.2
DAZ associated protein 2
chr6_+_32936353 2.87 ENST00000374825.4
bromodomain containing 2
chr7_-_115608304 2.82 ENST00000457268.1
transcription factor EC
chr1_-_228613026 2.81 ENST00000366696.1
histone cluster 3, H3
chr11_+_64323098 2.78 ENST00000301891.4
solute carrier family 22 (organic anion/urate transporter), member 11
chr19_-_5680499 2.76 ENST00000587589.1
chromosome 19 open reading frame 70
chr12_-_123011476 2.71 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
arginine/serine-rich coiled-coil 2
chr7_+_130020180 2.69 ENST00000481342.1
ENST00000011292.3
ENST00000604896.1
carboxypeptidase A1 (pancreatic)
chr10_+_93683519 2.69 ENST00000265990.6
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
chr12_+_51632638 2.67 ENST00000549732.2
DAZ associated protein 2
chr20_+_43803517 2.67 ENST00000243924.3
peptidase inhibitor 3, skin-derived
chr6_-_46620522 2.65 ENST00000275016.2
cytochrome P450, family 39, subfamily A, polypeptide 1
chr14_+_39734482 2.64 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
CTAGE family, member 5
chr8_-_56987057 2.61 ENST00000518875.1
ribosomal protein S20
chr17_-_43138357 2.58 ENST00000342350.5
dephospho-CoA kinase domain containing
chr9_-_98079965 2.57 ENST00000289081.3
Fanconi anemia, complementation group C
chr2_-_190627481 2.55 ENST00000264151.5
ENST00000520350.1
ENST00000521630.1
ENST00000517895.1
O-sialoglycoprotein endopeptidase-like 1
chr1_+_152635854 2.51 ENST00000368784.1
late cornified envelope 2D
chr7_+_43622664 2.50 ENST00000319357.5
serine/threonine kinase 17a
chr21_+_39644214 2.49 ENST00000438657.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr6_-_131949200 2.48 ENST00000539158.1
ENST00000368058.1
mediator complex subunit 23
chr10_+_102222798 2.48 ENST00000343737.5
wingless-type MMTV integration site family, member 8B
chr8_-_29940464 2.48 ENST00000521265.1
ENST00000536273.1
transmembrane protein 66
chr17_+_56315936 2.45 ENST00000543544.1
lactoperoxidase
chr19_+_5681011 2.43 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
hydroxysteroid (11-beta) dehydrogenase 1-like
chr19_+_782755 2.43 ENST00000606242.1
ENST00000586061.1
AC006273.5
chr1_-_6260896 2.39 ENST00000497965.1
ribosomal protein L22
chr6_+_88182643 2.35 ENST00000369556.3
ENST00000544441.1
ENST00000369552.4
ENST00000369557.5
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr17_-_34313685 2.35 ENST00000435911.2
ENST00000586216.1
ENST00000394509.4
chemokine (C-C motif) ligand 14
chr16_-_33647696 2.32 ENST00000558425.1
ENST00000569103.2
Uncharacterized protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 23.3 GO:1900159 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
5.0 14.9 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
4.3 21.4 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
3.9 11.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
3.7 18.3 GO:0002399 MHC class II protein complex assembly(GO:0002399)
3.3 9.9 GO:0002818 intracellular defense response(GO:0002818)
2.7 19.1 GO:0032119 sequestering of zinc ion(GO:0032119)
1.9 5.8 GO:0038178 complement component C5a signaling pathway(GO:0038178)
1.9 5.8 GO:0035470 positive regulation of vascular wound healing(GO:0035470) regulation of lactation(GO:1903487)
1.9 11.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
1.7 6.7 GO:0005986 sucrose biosynthetic process(GO:0005986)
1.6 6.5 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
1.5 6.2 GO:2000697 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
1.5 4.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
1.5 4.6 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
1.5 13.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.3 29.2 GO:0044146 negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
1.2 4.8 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.2 21.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
1.1 9.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
1.1 3.2 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
1.1 3.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
1.0 22.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
1.0 4.0 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
1.0 3.9 GO:0003335 corneocyte development(GO:0003335)
1.0 2.9 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.9 1.9 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.9 1.9 GO:0070662 mast cell proliferation(GO:0070662)
0.8 2.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.8 4.2 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.8 4.2 GO:1902023 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.8 6.1 GO:0070995 NADPH oxidation(GO:0070995)
0.7 4.5 GO:0006196 AMP catabolic process(GO:0006196)
0.7 8.0 GO:0043587 tongue morphogenesis(GO:0043587)
0.7 87.6 GO:0031295 T cell costimulation(GO:0031295)
0.7 5.0 GO:0033227 dsRNA transport(GO:0033227)
0.7 4.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.6 2.5 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.6 40.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.6 3.1 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.6 3.6 GO:0035624 receptor transactivation(GO:0035624)
0.6 15.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.6 25.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.6 1.7 GO:0071529 cementum mineralization(GO:0071529)
0.6 2.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.6 1.7 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.5 2.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.5 5.3 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.5 5.7 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.5 8.5 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.5 5.4 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.5 2.0 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.5 8.8 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.5 0.9 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.5 1.4 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.5 4.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.5 3.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.4 3.1 GO:0060992 response to fungicide(GO:0060992)
0.4 1.3 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.4 4.4 GO:0015791 polyol transport(GO:0015791)
0.4 5.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.4 1.3 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.4 3.3 GO:0032649 regulation of interferon-gamma production(GO:0032649)
0.4 2.0 GO:0046449 creatinine metabolic process(GO:0046449)
0.4 1.2 GO:0044793 negative regulation by host of viral process(GO:0044793)
0.4 4.0 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.4 3.9 GO:0007000 nucleolus organization(GO:0007000)
0.4 2.7 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.4 3.1 GO:0016926 protein desumoylation(GO:0016926)
0.4 2.3 GO:0019532 oxalate transport(GO:0019532)
0.4 1.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.4 2.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.4 34.6 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.4 3.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 34.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.3 1.4 GO:0035995 detection of muscle stretch(GO:0035995)
0.3 6.0 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.3 3.5 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.3 1.6 GO:0051182 coenzyme transport(GO:0051182)
0.3 3.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.3 0.9 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.3 2.8 GO:0015747 urate transport(GO:0015747)
0.3 2.7 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.3 3.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.3 3.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.3 0.9 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.3 5.6 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.3 3.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.3 0.8 GO:2000724 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.3 0.5 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.3 3.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.3 1.8 GO:0042126 nitrate metabolic process(GO:0042126)
0.3 5.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.2 1.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 2.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.2 1.0 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.2 1.7 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.2 1.6 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.2 1.2 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2 7.3 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.2 2.6 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.2 1.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 1.8 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 2.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 1.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 2.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 1.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 1.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.2 0.9 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.2 1.7 GO:0006531 aspartate metabolic process(GO:0006531)
0.2 1.4 GO:0070475 rRNA base methylation(GO:0070475)
0.2 1.2 GO:0001955 blood vessel maturation(GO:0001955)
0.2 14.2 GO:0045576 mast cell activation(GO:0045576)
0.2 2.3 GO:0090220 meiotic telomere clustering(GO:0045141) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.2 1.4 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 0.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 5.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 5.0 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.2 3.6 GO:0051181 cofactor transport(GO:0051181)
0.2 11.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 1.7 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2 1.7 GO:0032025 response to cobalt ion(GO:0032025)
0.1 1.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 1.5 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 2.7 GO:0007620 copulation(GO:0007620)
0.1 4.4 GO:0001945 lymph vessel development(GO:0001945)
0.1 1.6 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 1.0 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 18.8 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.4 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 1.8 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 3.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 2.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.9 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.4 GO:0015860 pyrimidine nucleobase transport(GO:0015855) purine nucleoside transmembrane transport(GO:0015860) purine nucleobase transmembrane transport(GO:1904823)
0.1 1.0 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.1 0.9 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 1.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.1 2.6 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 1.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 3.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 4.6 GO:0010107 potassium ion import(GO:0010107)
0.1 0.9 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.2 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.1 0.8 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 1.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 1.9 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 0.5 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 11.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 1.2 GO:0021554 optic nerve development(GO:0021554)
0.1 3.1 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 2.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 5.8 GO:0018149 peptide cross-linking(GO:0018149)
0.1 2.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 2.2 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.1 3.0 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 0.9 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1 0.3 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
0.1 1.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.8 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.2 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 3.6 GO:0015701 bicarbonate transport(GO:0015701)
0.1 3.1 GO:0001510 RNA methylation(GO:0001510)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 2.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 1.3 GO:0008203 cholesterol metabolic process(GO:0008203)
0.1 4.3 GO:0006968 cellular defense response(GO:0006968)
0.1 0.5 GO:0045023 G0 to G1 transition(GO:0045023)
0.1 2.1 GO:0007140 male meiosis(GO:0007140)
0.1 2.8 GO:0016233 telomere capping(GO:0016233)
0.1 0.9 GO:0005513 detection of calcium ion(GO:0005513)
0.1 3.0 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.1 4.0 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.3 GO:0098743 cell aggregation(GO:0098743)
0.1 0.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 5.8 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.1 2.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.9 GO:0021984 adenohypophysis development(GO:0021984)
0.1 1.6 GO:0016578 histone deubiquitination(GO:0016578)
0.1 1.1 GO:0019054 modulation by virus of host process(GO:0019054)
0.1 3.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.7 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.8 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 1.8 GO:0006298 mismatch repair(GO:0006298)
0.0 3.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.7 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 3.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.2 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 1.3 GO:0046039 GTP metabolic process(GO:0046039)
0.0 1.6 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 1.0 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 2.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 2.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 1.9 GO:0006826 iron ion transport(GO:0006826)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)
0.0 1.2 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.6 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 1.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 1.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 2.1 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.9 GO:0030574 collagen catabolic process(GO:0030574)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 108.4 GO:0042613 MHC class II protein complex(GO:0042613)
4.7 33.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
3.9 11.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
3.9 31.0 GO:1990111 spermatoproteasome complex(GO:1990111)
1.7 10.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
1.5 6.1 GO:1990031 pinceau fiber(GO:1990031)
1.4 6.8 GO:0036398 TCR signalosome(GO:0036398)
1.2 3.5 GO:0060053 neurofilament cytoskeleton(GO:0060053)
1.0 11.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.9 9.8 GO:0042611 MHC protein complex(GO:0042611)
0.8 41.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.6 11.9 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.5 30.7 GO:0001772 immunological synapse(GO:0001772)
0.5 2.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.5 4.3 GO:0005579 membrane attack complex(GO:0005579)
0.4 1.3 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.4 2.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 26.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4 1.7 GO:0043293 apoptosome(GO:0043293)
0.4 4.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 1.7 GO:0071546 pi-body(GO:0071546)
0.3 6.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.3 1.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.3 1.7 GO:0032444 activin responsive factor complex(GO:0032444)
0.3 7.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 11.2 GO:0045095 keratin filament(GO:0045095)
0.3 28.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 5.5 GO:0042101 T cell receptor complex(GO:0042101)
0.2 1.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 1.5 GO:0008537 proteasome activator complex(GO:0008537)
0.2 13.1 GO:0016235 aggresome(GO:0016235)
0.2 3.1 GO:0030478 actin cap(GO:0030478)
0.2 4.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 1.7 GO:0032389 MutLalpha complex(GO:0032389)
0.2 1.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 6.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 2.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 7.3 GO:0001533 cornified envelope(GO:0001533)
0.2 4.0 GO:0034451 centriolar satellite(GO:0034451)
0.2 2.0 GO:0097433 dense body(GO:0097433)
0.2 1.9 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.2 5.2 GO:0042629 mast cell granule(GO:0042629)
0.1 17.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 0.9 GO:0016600 flotillin complex(GO:0016600)
0.1 4.6 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 2.8 GO:0005861 troponin complex(GO:0005861)
0.1 0.4 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 13.1 GO:0035579 specific granule membrane(GO:0035579)
0.1 10.9 GO:0005814 centriole(GO:0005814)
0.1 2.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 2.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 10.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 1.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 23.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 8.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.3 GO:0033268 node of Ranvier(GO:0033268)
0.1 4.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 4.4 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 4.4 GO:0030175 filopodium(GO:0030175)
0.0 3.1 GO:0005657 replication fork(GO:0005657)
0.0 3.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 2.6 GO:0015030 Cajal body(GO:0015030)
0.0 3.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0031105 septin complex(GO:0031105)
0.0 2.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 7.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.5 GO:0016605 PML body(GO:0016605)
0.0 1.0 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0032590 dendrite membrane(GO:0032590)
0.0 2.1 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.4 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.0 0.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.0 0.9 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 3.5 GO:0016607 nuclear speck(GO:0016607)
0.0 0.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.6 GO:0000790 nuclear chromatin(GO:0000790)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 18.0 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
5.2 72.6 GO:0032395 MHC class II receptor activity(GO:0032395)
5.0 14.9 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
2.7 8.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
2.3 11.5 GO:0023024 MHC class I protein complex binding(GO:0023024)
1.9 5.8 GO:0004878 complement component C5a receptor activity(GO:0004878)
1.7 6.7 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.5 4.6 GO:0004914 interleukin-5 receptor activity(GO:0004914)
1.5 45.6 GO:0042605 peptide antigen binding(GO:0042605)
1.4 4.3 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
1.4 4.2 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
1.4 5.5 GO:0042289 MHC class II protein binding(GO:0042289)
1.3 3.9 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
1.3 6.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
1.1 6.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
1.0 31.0 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.9 3.7 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.9 12.0 GO:0050700 CARD domain binding(GO:0050700)
0.8 5.0 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.8 3.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.8 4.0 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.8 2.3 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.8 41.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.7 2.9 GO:0005502 11-cis retinal binding(GO:0005502)
0.6 1.9 GO:0030350 iron-responsive element binding(GO:0030350)
0.6 2.5 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.6 3.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.6 1.8 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.6 5.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.6 1.7 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.5 4.4 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.5 6.0 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.5 31.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.5 5.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.5 1.6 GO:0051185 coenzyme transporter activity(GO:0051185)
0.5 3.0 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.5 4.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 9.3 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.5 16.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.5 1.4 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.5 2.3 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.4 1.8 GO:0008940 nitrate reductase activity(GO:0008940)
0.4 11.4 GO:0031489 myosin V binding(GO:0031489)
0.4 1.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.4 3.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.4 3.6 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 6.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.3 1.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 6.6 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.3 4.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 2.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 2.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 1.9 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.3 2.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.3 1.5 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.3 0.9 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.3 2.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 0.8 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.3 3.5 GO:0030957 Tat protein binding(GO:0030957)
0.3 0.8 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.3 4.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 3.1 GO:0045159 myosin II binding(GO:0045159)
0.3 0.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.3 4.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 5.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 1.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 1.5 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.2 1.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 10.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 7.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.8 GO:0003696 satellite DNA binding(GO:0003696)
0.2 8.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 6.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 9.3 GO:0050699 WW domain binding(GO:0050699)
0.2 3.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 3.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 1.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 8.0 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.2 15.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 7.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 1.9 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 0.9 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.2 6.1 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.2 2.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 3.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 2.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 1.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 1.9 GO:0003951 NAD+ kinase activity(GO:0003951)
0.2 29.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 0.9 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.2 0.7 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.2 21.5 GO:0003823 antigen binding(GO:0003823)
0.2 1.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 1.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.2 1.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 1.2 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.1 GO:0005497 androgen binding(GO:0005497)
0.1 1.4 GO:0031433 telethonin binding(GO:0031433)
0.1 1.7 GO:0043199 sulfate binding(GO:0043199)
0.1 2.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 3.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.4 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350) pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.1 1.3 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.0 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 3.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.6 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.8 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 1.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 3.1 GO:0070412 R-SMAD binding(GO:0070412)
0.1 10.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 3.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 1.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 1.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 2.4 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.0 GO:0070403 NAD+ binding(GO:0070403)
0.1 6.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 1.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 2.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.8 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1 3.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 7.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.1 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 5.8 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 2.3 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 1.1 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 3.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 2.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 3.0 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 4.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 2.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 3.8 GO:0031072 heat shock protein binding(GO:0031072)
0.0 8.0 GO:0008201 heparin binding(GO:0008201)
0.0 1.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.6 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 1.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.2 GO:0008009 chemokine activity(GO:0008009)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.7 GO:0004386 helicase activity(GO:0004386)
0.0 1.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.7 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 4.4 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.1 GO:0043621 protein self-association(GO:0043621)
0.0 3.4 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 2.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 4.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 3.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 12.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.6 14.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.6 33.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.5 4.6 PID IL5 PATHWAY IL5-mediated signaling events
0.5 23.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.4 11.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.4 9.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.4 10.9 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.4 15.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.3 5.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.3 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 3.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 4.4 PID IL23 PATHWAY IL23-mediated signaling events
0.2 9.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 2.3 PID IL27 PATHWAY IL27-mediated signaling events
0.2 20.1 PID AP1 PATHWAY AP-1 transcription factor network
0.2 1.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 3.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 4.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 1.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 7.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 10.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 4.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 6.5 PID AURORA A PATHWAY Aurora A signaling
0.1 1.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 4.0 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 3.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 5.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 4.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 4.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.3 PID CD40 PATHWAY CD40/CD40L signaling
0.1 1.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 5.7 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 6.3 PID E2F PATHWAY E2F transcription factor network
0.1 3.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 14.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.0 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.4 PID ATM PATHWAY ATM pathway
0.0 2.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 111.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.0 9.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.8 5.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.7 28.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.5 51.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.5 3.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.5 14.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.4 32.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.4 11.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.4 5.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.3 6.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 2.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 12.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 3.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 5.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 6.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.2 17.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 12.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 4.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.2 4.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2 3.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.2 7.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 2.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 3.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 6.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 4.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 4.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 4.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 5.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 3.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 18.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 3.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 4.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 17.5 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.1 1.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 3.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.6 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 0.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 0.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 2.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 2.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 2.3 REACTOME TRANSLATION Genes involved in Translation
0.0 4.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 3.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements