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GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for IRF7

Z-value: 1.22

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Transcription factors associated with IRF7

Gene Symbol Gene ID Gene Info
IRF7
ENSG00000185507.15 interferon regulatory factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF7hg19_v2_chr11_-_615570_615728-0.291.2e-05Click!

Activity profile of IRF7 motif

Sorted Z-values of IRF7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_55237484 29.08 ENST00000394609.2
RTN4
reticulon 4
chr2_-_151344172 28.03 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr12_+_19358228 27.27 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr4_+_41614909 24.42 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chrX_+_102631248 23.52 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_+_102883620 22.61 ENST00000372626.3
TCEAL1
transcription elongation factor A (SII)-like 1
chrX_+_103031421 20.71 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
PLP1
proteolipid protein 1
chr12_-_50616382 20.62 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chrX_+_103031758 19.83 ENST00000303958.2
ENST00000361621.2
PLP1
proteolipid protein 1
chr12_-_118498958 18.44 ENST00000315436.3
WSB2
WD repeat and SOCS box containing 2
chr11_+_19799327 17.49 ENST00000540292.1
NAV2
neuron navigator 2
chr10_+_91152303 17.09 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr3_-_47950745 15.75 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr1_+_948803 15.46 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr12_-_50616122 13.44 ENST00000552823.1
ENST00000552909.1
LIMA1
LIM domain and actin binding 1
chr12_-_26278030 13.44 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr5_+_140749803 13.42 ENST00000576222.1
PCDHGB3
protocadherin gamma subfamily B, 3
chr15_+_65843130 13.41 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr15_+_80733570 13.28 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr9_-_36276966 13.18 ENST00000543356.2
ENST00000396594.3
GNE
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr8_+_80523321 12.91 ENST00000518111.1
STMN2
stathmin-like 2
chr17_-_76975925 12.86 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
LGALS3BP
lectin, galactoside-binding, soluble, 3 binding protein
chr11_+_9406169 12.85 ENST00000379719.3
ENST00000527431.1
IPO7
importin 7
chr7_+_75931861 12.67 ENST00000248553.6
HSPB1
heat shock 27kDa protein 1
chrX_-_13835461 12.42 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr14_-_69446034 11.92 ENST00000193403.6
ACTN1
actinin, alpha 1
chr1_-_149900122 11.91 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr14_-_102552659 11.90 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr8_+_26150628 11.84 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr4_+_41614720 11.76 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr11_+_69455855 11.45 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr5_+_140734570 11.43 ENST00000571252.1
PCDHGA4
protocadherin gamma subfamily A, 4
chr18_-_21977748 11.19 ENST00000399441.4
ENST00000319481.3
OSBPL1A
oxysterol binding protein-like 1A
chr21_-_27542972 11.18 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
APP
amyloid beta (A4) precursor protein
chr14_+_58711539 10.90 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3
chr14_-_69445968 10.87 ENST00000438964.2
ACTN1
actinin, alpha 1
chr14_+_73563735 10.84 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr9_+_33264861 10.67 ENST00000223500.8
CHMP5
charged multivesicular body protein 5
chr8_+_132916318 10.63 ENST00000254624.5
ENST00000522709.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr4_-_176923483 10.34 ENST00000280187.7
ENST00000512509.1
GPM6A
glycoprotein M6A
chr1_-_246357029 10.19 ENST00000391836.2
SMYD3
SET and MYND domain containing 3
chrX_+_102883887 10.15 ENST00000372625.3
ENST00000372624.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr15_+_96875657 10.02 ENST00000559679.1
ENST00000394171.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr3_-_114035026 9.94 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr20_+_10199468 9.72 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chrX_-_13835147 9.62 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr12_-_54652060 9.43 ENST00000552562.1
CBX5
chromobox homolog 5
chr9_+_33265011 9.39 ENST00000419016.2
CHMP5
charged multivesicular body protein 5
chr11_-_119293872 9.39 ENST00000524970.1
THY1
Thy-1 cell surface antigen
chr14_-_70883708 9.20 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr15_-_37393406 9.18 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr5_-_146461027 9.10 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr4_+_113739244 9.10 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ANK2
ankyrin 2, neuronal
chr1_+_165796753 8.92 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr11_-_111794446 8.77 ENST00000527950.1
CRYAB
crystallin, alpha B
chr10_-_95242044 8.57 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chrX_-_20236970 8.51 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr7_-_123197733 8.49 ENST00000470123.1
ENST00000471770.1
NDUFA5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr9_-_21187598 8.49 ENST00000421715.1
IFNA4
interferon, alpha 4
chr1_-_21377383 8.41 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr2_-_37384175 8.21 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
chr10_-_95241951 8.15 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr1_-_21377447 8.11 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chrX_+_21958674 8.04 ENST00000404933.2
SMS
spermine synthase
chr1_+_84630645 8.03 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_55352834 7.86 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chr4_-_87281224 7.86 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr7_-_134143841 7.84 ENST00000285930.4
AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr8_+_85618155 7.78 ENST00000523850.1
ENST00000521376.1
RALYL
RALY RNA binding protein-like
chrX_+_77154935 7.74 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chrX_+_146993534 7.68 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
FMR1
fragile X mental retardation 1
chr17_-_47723943 7.41 ENST00000510476.1
ENST00000503676.1
SPOP
speckle-type POZ protein
chrX_-_102941596 7.38 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
MORF4L2
mortality factor 4 like 2
chr17_-_65362678 7.35 ENST00000357146.4
ENST00000356126.3
PSMD12
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chrX_+_21958814 7.23 ENST00000379404.1
ENST00000415881.2
SMS
spermine synthase
chrX_+_146993449 7.19 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
FMR1
fragile X mental retardation 1
chr15_+_78832747 7.13 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
chrX_+_56590002 7.08 ENST00000338222.5
UBQLN2
ubiquilin 2
chr14_+_90864504 7.02 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr1_+_84630053 6.98 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_92919043 6.95 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr12_+_79258547 6.91 ENST00000457153.2
SYT1
synaptotagmin I
chr18_+_12947981 6.90 ENST00000262124.11
SEH1L
SEH1-like (S. cerevisiae)
chr2_-_55277692 6.82 ENST00000394611.2
RTN4
reticulon 4
chr8_+_109455845 6.73 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr15_+_96876340 6.72 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr6_+_63921351 6.71 ENST00000370659.1
FKBP1C
FK506 binding protein 1C
chr9_-_21305312 6.66 ENST00000259555.4
IFNA5
interferon, alpha 5
chr10_+_91092241 6.59 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chrX_+_119737806 6.51 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr4_-_87281196 6.47 ENST00000359221.3
MAPK10
mitogen-activated protein kinase 10
chr11_-_33757950 6.46 ENST00000533403.1
ENST00000528700.1
ENST00000527577.1
ENST00000395850.3
ENST00000351554.3
CD59
CD59 molecule, complement regulatory protein
chr11_-_321050 6.41 ENST00000399808.4
IFITM3
interferon induced transmembrane protein 3
chr9_-_21228221 6.30 ENST00000413767.2
IFNA17
interferon, alpha 17
chr4_-_139163491 6.29 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr7_+_134576151 6.23 ENST00000393118.2
CALD1
caldesmon 1
chr11_+_46402297 6.15 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chrX_-_34675391 6.07 ENST00000275954.3
TMEM47
transmembrane protein 47
chr7_+_112063192 6.06 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr1_-_154580616 6.05 ENST00000368474.4
ADAR
adenosine deaminase, RNA-specific
chr8_+_54764346 5.97 ENST00000297313.3
ENST00000344277.6
RGS20
regulator of G-protein signaling 20
chr9_-_21202204 5.86 ENST00000239347.3
IFNA7
interferon, alpha 7
chr6_+_151561506 5.85 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr3_+_141106643 5.79 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr14_-_54908043 5.79 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr5_-_11589131 5.72 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chrX_-_48980098 5.68 ENST00000156109.5
GPKOW
G patch domain and KOW motifs
chr7_+_55177416 5.63 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr10_+_94352956 5.61 ENST00000260731.3
KIF11
kinesin family member 11
chr2_-_190044480 5.59 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr7_-_93519471 5.54 ENST00000451238.1
TFPI2
tissue factor pathway inhibitor 2
chr3_-_197026152 5.52 ENST00000419354.1
DLG1
discs, large homolog 1 (Drosophila)
chr14_-_21924209 5.47 ENST00000557364.1
CHD8
chromodomain helicase DNA binding protein 8
chr2_+_120687335 5.45 ENST00000544261.1
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr10_-_91174215 5.40 ENST00000371837.1
LIPA
lipase A, lysosomal acid, cholesterol esterase
chr1_-_103574024 5.35 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
COL11A1
collagen, type XI, alpha 1
chr13_-_46543805 5.33 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr6_+_151561085 5.33 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr7_+_100797678 5.23 ENST00000337619.5
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr10_+_95517660 5.22 ENST00000371413.3
LGI1
leucine-rich, glioma inactivated 1
chr1_+_155829286 5.22 ENST00000368324.4
SYT11
synaptotagmin XI
chr11_+_57480046 5.15 ENST00000378312.4
ENST00000278422.4
TMX2
thioredoxin-related transmembrane protein 2
chr12_+_12878829 5.11 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr15_+_42694573 5.10 ENST00000397200.4
ENST00000569827.1
CAPN3
calpain 3, (p94)
chrX_+_100878079 5.09 ENST00000471229.2
ARMCX3
armadillo repeat containing, X-linked 3
chr17_+_3379284 5.05 ENST00000263080.2
ASPA
aspartoacylase
chr16_-_4850471 5.05 ENST00000592019.1
ENST00000586153.1
ROGDI
rogdi homolog (Drosophila)
chr5_+_34915444 5.04 ENST00000336767.5
BRIX1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr9_-_140353748 4.96 ENST00000371472.2
ENST00000371475.3
ENST00000265663.7
ENST00000437259.1
ENST00000392812.4
ENST00000371474.3
ENST00000371473.3
NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr6_-_116601044 4.96 ENST00000368608.3
TSPYL1
TSPY-like 1
chr4_-_77135046 4.95 ENST00000264896.2
SCARB2
scavenger receptor class B, member 2
chr12_+_15699286 4.95 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr5_-_11588907 4.94 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chrX_+_23682379 4.92 ENST00000379349.1
PRDX4
peroxiredoxin 4
chr11_+_46402583 4.89 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr7_-_30066233 4.88 ENST00000222803.5
FKBP14
FK506 binding protein 14, 22 kDa
chr17_+_41363854 4.71 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr14_-_35099315 4.69 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
SNX6
sorting nexin 6
chr10_+_95517566 4.67 ENST00000542308.1
LGI1
leucine-rich, glioma inactivated 1
chr7_+_100797726 4.67 ENST00000429457.1
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chrX_-_99891796 4.66 ENST00000373020.4
TSPAN6
tetraspanin 6
chr7_-_42971759 4.63 ENST00000538645.1
ENST00000445517.1
ENST00000223321.4
PSMA2
proteasome (prosome, macropain) subunit, alpha type, 2
chr11_-_117186946 4.62 ENST00000313005.6
ENST00000528053.1
BACE1
beta-site APP-cleaving enzyme 1
chr9_-_13175823 4.58 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr11_+_27062272 4.57 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr10_+_95517616 4.54 ENST00000371418.4
LGI1
leucine-rich, glioma inactivated 1
chr8_+_101162812 4.52 ENST00000353107.3
ENST00000522439.1
POLR2K
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr13_-_30424821 4.48 ENST00000380680.4
UBL3
ubiquitin-like 3
chr11_+_47600562 4.47 ENST00000263774.4
ENST00000529276.1
ENST00000528192.1
ENST00000530295.1
ENST00000534208.1
ENST00000534716.2
NDUFS3
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
chr7_+_121513143 4.43 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chrX_+_80457442 4.41 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr4_+_113568207 4.35 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr18_+_3451646 4.34 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr3_-_194393206 4.33 ENST00000265245.5
LSG1
large 60S subunit nuclear export GTPase 1
chr20_-_33999766 4.28 ENST00000349714.5
ENST00000438533.1
ENST00000359226.2
ENST00000374384.2
ENST00000374377.5
ENST00000407996.2
ENST00000424405.1
ENST00000542501.1
ENST00000397554.1
ENST00000540457.1
ENST00000374380.2
ENST00000374385.5
UQCC1
ubiquinol-cytochrome c reductase complex assembly factor 1
chr3_+_154797877 4.28 ENST00000462745.1
ENST00000493237.1
MME
membrane metallo-endopeptidase
chr21_-_35281399 4.28 ENST00000418933.1
ATP5O
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr15_+_80364901 4.18 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
ZFAND6
zinc finger, AN1-type domain 6
chr8_+_97597148 4.17 ENST00000521590.1
SDC2
syndecan 2
chr11_+_46402744 4.16 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr3_-_42306248 4.16 ENST00000334681.5
CCK
cholecystokinin
chr19_+_17378278 4.14 ENST00000596335.1
ENST00000601436.1
ENST00000595632.1
BABAM1
BRISC and BRCA1 A complex member 1
chr9_-_21995300 4.13 ENST00000498628.2
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr6_-_131291572 4.07 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr20_-_3767324 4.03 ENST00000379751.4
CENPB
centromere protein B, 80kDa
chr2_-_37899323 3.96 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr12_+_113376157 3.94 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr3_+_119316689 3.90 ENST00000273371.4
PLA1A
phospholipase A1 member A
chr12_-_51422017 3.84 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chrX_-_100914781 3.83 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
ARMCX2
armadillo repeat containing, X-linked 2
chr9_+_21409146 3.80 ENST00000380205.1
IFNA8
interferon, alpha 8
chr18_+_3451584 3.78 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr10_+_115439630 3.76 ENST00000369318.3
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr11_+_35211429 3.74 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44
CD44 molecule (Indian blood group)
chr17_-_46682321 3.70 ENST00000225648.3
ENST00000484302.2
HOXB6
homeobox B6
chr14_-_100841670 3.70 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
WARS
tryptophanyl-tRNA synthetase
chr14_-_24615805 3.65 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr10_+_115439699 3.64 ENST00000369315.1
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr13_+_29233218 3.63 ENST00000380842.4
POMP
proteasome maturation protein
chr10_+_115439282 3.62 ENST00000369321.2
ENST00000345633.4
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr20_-_48732472 3.60 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr17_-_38978847 3.60 ENST00000269576.5
KRT10
keratin 10
chr20_+_25388293 3.59 ENST00000262460.4
ENST00000429262.2
GINS1
GINS complex subunit 1 (Psf1 homolog)
chr18_+_3262954 3.58 ENST00000584539.1
MYL12B
myosin, light chain 12B, regulatory
chr9_-_32526299 3.56 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr4_-_48782259 3.55 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL
FRY-like
chr2_-_188419200 3.53 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr19_+_17378159 3.52 ENST00000598188.1
ENST00000359435.4
ENST00000599474.1
ENST00000599057.1
ENST00000601043.1
ENST00000447614.2
BABAM1
BRISC and BRCA1 A complex member 1
chr1_-_94374946 3.52 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chr12_-_27090896 3.51 ENST00000539625.1
ENST00000538727.1
ASUN
asunder spermatogenesis regulator
chr2_+_169312350 3.51 ENST00000305747.6
CERS6
ceramide synthase 6
chr13_+_53216565 3.50 ENST00000357495.2
HNRNPA1L2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr12_+_27863706 3.49 ENST00000081029.3
ENST00000538315.1
ENST00000542791.1
MRPS35
mitochondrial ribosomal protein S35
chr15_+_91643442 3.49 ENST00000394232.1
SV2B
synaptic vesicle glycoprotein 2B
chr15_-_41624685 3.48 ENST00000560640.1
ENST00000220514.3
OIP5
Opa interacting protein 5
chr16_+_14726672 3.46 ENST00000261658.2
ENST00000563971.1
BFAR
bifunctional apoptosis regulator
chr12_-_58165870 3.45 ENST00000257848.7
METTL1
methyltransferase like 1
chr19_+_30863271 3.44 ENST00000355537.3
ZNF536
zinc finger protein 536
chr15_+_63354769 3.42 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr1_-_115300579 3.39 ENST00000358528.4
ENST00000525132.1
CSDE1
cold shock domain containing E1, RNA-binding

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
5.1 15.3 GO:0006597 spermine biosynthetic process(GO:0006597)
4.4 17.5 GO:0021564 vagus nerve development(GO:0021564)
4.2 16.7 GO:0009956 radial pattern formation(GO:0009956)
4.0 48.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
4.0 11.9 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
3.2 12.7 GO:0099640 axo-dendritic protein transport(GO:0099640)
3.1 9.4 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
3.1 12.3 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
3.0 14.9 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
3.0 11.9 GO:0043335 protein unfolding(GO:0043335)
2.9 14.5 GO:0097338 response to clozapine(GO:0097338)
2.6 15.7 GO:0051012 microtubule sliding(GO:0051012)
2.6 7.8 GO:0006059 hexitol metabolic process(GO:0006059) response to methylglyoxal(GO:0051595)
2.6 10.4 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
2.5 15.3 GO:0030421 defecation(GO:0030421)
2.3 6.9 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
2.3 38.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
2.2 11.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
2.2 8.9 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
2.2 22.0 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.2 6.5 GO:0002188 translation reinitiation(GO:0002188)
2.0 6.1 GO:0007518 myoblast fate determination(GO:0007518)
2.0 6.0 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
1.9 9.7 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.9 5.6 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
1.8 14.3 GO:0007258 JUN phosphorylation(GO:0007258)
1.7 5.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
1.7 6.7 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.7 5.0 GO:0006533 aspartate catabolic process(GO:0006533)
1.7 6.6 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
1.6 4.9 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
1.6 32.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
1.6 6.5 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
1.6 7.9 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
1.5 16.7 GO:0001778 plasma membrane repair(GO:0001778)
1.4 5.6 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
1.4 11.0 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.3 20.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
1.3 5.0 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
1.2 7.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.2 4.8 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
1.2 8.2 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
1.2 5.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
1.1 9.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
1.1 3.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.1 25.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
1.1 5.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
1.1 6.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.1 4.3 GO:0071492 cellular response to UV-A(GO:0071492)
1.0 7.3 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
1.0 11.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
1.0 9.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
1.0 13.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
1.0 3.0 GO:0006624 vacuolar protein processing(GO:0006624)
1.0 3.0 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
1.0 4.9 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.9 2.8 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.9 22.8 GO:0030220 platelet formation(GO:0030220)
0.9 3.6 GO:0043248 proteasome assembly(GO:0043248)
0.9 3.6 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.9 2.7 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.9 3.5 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.9 5.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.8 5.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.8 13.4 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.8 2.4 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.8 5.5 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.8 2.4 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.8 6.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.8 5.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.7 11.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.7 3.7 GO:1903588 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.7 2.9 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.7 6.6 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.7 2.2 GO:0021569 rhombomere 3 development(GO:0021569)
0.7 2.1 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.7 10.2 GO:0006999 nuclear pore organization(GO:0006999)
0.7 2.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.7 4.7 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.6 1.9 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.6 4.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.6 11.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.6 4.2 GO:0008218 bioluminescence(GO:0008218)
0.6 35.0 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.6 2.9 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.6 2.3 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.6 2.3 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.6 4.4 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.5 4.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.5 4.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.5 5.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.5 8.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.5 6.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.5 4.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.5 5.9 GO:0035455 response to interferon-alpha(GO:0035455)
0.4 3.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.4 6.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.4 1.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.4 3.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.4 2.1 GO:0015692 lead ion transport(GO:0015692)
0.4 2.5 GO:0044857 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.4 1.3 GO:0086044 pulmonary valve formation(GO:0003193) atrial ventricular junction remodeling(GO:0003294) foramen ovale closure(GO:0035922) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.4 3.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.4 4.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.4 2.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 8.5 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.4 1.1 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.4 7.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 2.8 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 10.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 3.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.3 3.6 GO:0042118 endothelial cell activation(GO:0042118)
0.3 6.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.3 4.0 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.3 1.6 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.3 3.3 GO:0006554 lysine catabolic process(GO:0006554)
0.3 3.3 GO:0030042 actin filament depolymerization(GO:0030042)
0.3 5.6 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.3 4.1 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.3 0.9 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.3 2.0 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.3 7.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.3 12.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 2.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.3 1.7 GO:0061635 regulation of protein complex stability(GO:0061635)
0.3 11.5 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.3 5.7 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.3 1.6 GO:0070383 DNA cytosine deamination(GO:0070383)
0.3 6.2 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.3 1.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.3 0.8 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.3 29.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.3 2.4 GO:0034214 protein hexamerization(GO:0034214)
0.3 2.6 GO:0060013 righting reflex(GO:0060013)
0.3 0.3 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.3 1.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2 12.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 1.0 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.2 6.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 10.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.2 1.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 5.5 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.2 3.0 GO:0006511 ubiquitin-dependent protein catabolic process(GO:0006511)
0.2 1.6 GO:0006102 isocitrate metabolic process(GO:0006102)
0.2 0.7 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.2 2.9 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.2 13.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 2.9 GO:0016081 synaptic vesicle docking(GO:0016081)
0.2 2.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.2 9.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.2 1.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.2 15.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.2 2.4 GO:0051601 exocyst localization(GO:0051601)
0.2 0.6 GO:0071314 cellular response to cocaine(GO:0071314)
0.2 11.6 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.2 4.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 0.6 GO:0045112 integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.2 1.6 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 0.8 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.2 1.1 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 0.7 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 2.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.7 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.2 0.5 GO:1901524 regulation of macromitophagy(GO:1901524) positive regulation of macromitophagy(GO:1901526) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.2 1.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 6.9 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 10.9 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 7.1 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.2 0.8 GO:0051552 flavone metabolic process(GO:0051552)
0.2 33.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.2 3.1 GO:0071420 cellular response to histamine(GO:0071420)
0.2 0.3 GO:0060437 lung growth(GO:0060437)
0.2 3.8 GO:0001783 B cell apoptotic process(GO:0001783)
0.2 1.4 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.0 GO:1901529 positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 5.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.3 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 1.4 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.1 2.9 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 1.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 2.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 4.5 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.1 1.6 GO:0071285 cellular response to lithium ion(GO:0071285) establishment of integrated proviral latency(GO:0075713)
0.1 0.8 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 6.1 GO:0008542 visual learning(GO:0008542)
0.1 1.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 3.0 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.9 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.5 GO:0030070 insulin processing(GO:0030070)
0.1 0.5 GO:1904141 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 4.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 2.8 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.1 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 3.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 1.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 1.3 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 1.8 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.1 2.4 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 3.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 5.8 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.4 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.1 9.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 0.3 GO:0051597 response to methylmercury(GO:0051597)
0.1 8.4 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.1 1.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 32.3 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.1 0.2 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.1 1.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 2.8 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 1.0 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 1.7 GO:0043276 anoikis(GO:0043276)
0.1 5.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 9.9 GO:0007411 axon guidance(GO:0007411)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 2.1 GO:0070527 platelet aggregation(GO:0070527)
0.0 1.4 GO:0006400 tRNA modification(GO:0006400)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 5.8 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 1.4 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 2.5 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.8 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.8 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 1.7 GO:0021549 cerebellum development(GO:0021549)
0.0 0.4 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 2.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 1.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 1.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0044804 nucleophagy(GO:0044804)
0.0 0.4 GO:0033189 response to vitamin A(GO:0033189)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 4.6 GO:0043687 post-translational protein modification(GO:0043687)
0.0 3.9 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 14.9 GO:0019034 viral replication complex(GO:0019034)
2.4 9.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
2.4 2.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
2.1 25.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
2.0 7.8 GO:0097454 Schwann cell microvillus(GO:0097454)
1.9 38.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
1.9 5.6 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
1.9 5.6 GO:0005588 collagen type V trimer(GO:0005588)
1.7 6.9 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.6 11.2 GO:1990812 growth cone filopodium(GO:1990812)
1.5 16.7 GO:0005614 interstitial matrix(GO:0005614)
1.5 4.4 GO:0072534 perineuronal net(GO:0072534)
1.5 22.1 GO:0005916 fascia adherens(GO:0005916)
1.4 9.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
1.3 5.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.2 6.0 GO:0044530 supraspliceosomal complex(GO:0044530)
1.1 3.4 GO:0018444 translation release factor complex(GO:0018444)
1.0 6.1 GO:0008537 proteasome activator complex(GO:0008537)
1.0 15.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.0 6.9 GO:0061700 GATOR2 complex(GO:0061700)
1.0 13.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
1.0 7.7 GO:0070552 BRISC complex(GO:0070552)
0.9 4.7 GO:0097422 tubular endosome(GO:0097422)
0.9 3.6 GO:0000811 GINS complex(GO:0000811)
0.9 6.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.8 2.4 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.8 16.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.7 6.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.7 25.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.7 7.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.7 3.6 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.7 12.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.7 13.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.7 3.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.7 6.7 GO:0097255 R2TP complex(GO:0097255)
0.7 6.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.7 7.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.6 9.2 GO:0030478 actin cap(GO:0030478)
0.6 6.6 GO:0016600 flotillin complex(GO:0016600)
0.6 5.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.6 3.0 GO:0033503 HULC complex(GO:0033503)
0.6 5.3 GO:0005915 zonula adherens(GO:0005915)
0.6 2.8 GO:0071797 LUBAC complex(GO:0071797)
0.5 14.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.5 11.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.5 10.3 GO:0044295 axonal growth cone(GO:0044295)
0.5 7.0 GO:0097512 cardiac myofibril(GO:0097512)
0.5 5.5 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.5 7.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.4 6.7 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.4 35.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.4 1.8 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.4 2.1 GO:0070826 paraferritin complex(GO:0070826)
0.4 11.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.4 5.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 2.6 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.3 4.2 GO:0043203 axon hillock(GO:0043203)
0.3 5.8 GO:0032059 bleb(GO:0032059)
0.3 1.7 GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.3 2.3 GO:0000813 ESCRT I complex(GO:0000813)
0.3 11.9 GO:0031430 M band(GO:0031430)
0.3 4.1 GO:0008091 spectrin(GO:0008091)
0.3 12.7 GO:1904115 axon cytoplasm(GO:1904115)
0.3 3.5 GO:0010369 chromocenter(GO:0010369)
0.3 1.6 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.3 2.3 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.3 4.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 3.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 4.8 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.2 6.3 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 3.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 12.6 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.2 16.4 GO:0072686 mitotic spindle(GO:0072686)
0.2 2.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 39.8 GO:0043209 myelin sheath(GO:0043209)
0.2 2.8 GO:0035102 PRC1 complex(GO:0035102)
0.2 2.4 GO:0005686 U2 snRNP(GO:0005686)
0.2 1.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.9 GO:0031905 early endosome lumen(GO:0031905)
0.2 5.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 2.5 GO:0001533 cornified envelope(GO:0001533)
0.2 11.4 GO:0005643 nuclear pore(GO:0005643)
0.2 2.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 4.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 3.6 GO:0099738 cell cortex region(GO:0099738)
0.2 5.6 GO:0005871 kinesin complex(GO:0005871)
0.2 0.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 1.3 GO:0042382 paraspeckles(GO:0042382)
0.1 8.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 7.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 4.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 2.8 GO:0070822 Sin3-type complex(GO:0070822)
0.1 7.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 3.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 2.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 8.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 6.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 8.7 GO:0005901 caveola(GO:0005901)
0.1 2.9 GO:0030686 90S preribosome(GO:0030686)
0.1 24.4 GO:0005770 late endosome(GO:0005770)
0.1 15.2 GO:0030427 site of polarized growth(GO:0030427)
0.1 13.7 GO:0043204 perikaryon(GO:0043204)
0.1 2.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 7.1 GO:0005776 autophagosome(GO:0005776)
0.1 4.3 GO:0015030 Cajal body(GO:0015030)
0.1 3.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 2.9 GO:0045171 intercellular bridge(GO:0045171)
0.1 13.7 GO:0005681 spliceosomal complex(GO:0005681)
0.1 1.3 GO:0005922 connexon complex(GO:0005922)
0.1 1.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.1 3.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 2.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 4.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 3.1 GO:0042641 actomyosin(GO:0042641)
0.1 7.8 GO:0008021 synaptic vesicle(GO:0008021)
0.1 0.9 GO:0030425 dendrite(GO:0030425)
0.1 4.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 8.1 GO:0005840 ribosome(GO:0005840)
0.0 2.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 16.1 GO:0005925 focal adhesion(GO:0005925)
0.0 2.7 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 8.0 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 2.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.2 GO:0005874 microtubule(GO:0005874)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.9 GO:0070821 tertiary granule membrane(GO:0070821)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.7 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
3.4 40.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
3.0 14.9 GO:0034046 poly(G) binding(GO:0034046)
2.7 8.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
2.7 27.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
2.4 14.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
2.3 32.7 GO:0005132 type I interferon receptor binding(GO:0005132)
1.5 4.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
1.5 13.4 GO:0043426 MRF binding(GO:0043426)
1.4 6.9 GO:0030348 syntaxin-3 binding(GO:0030348)
1.3 10.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.3 15.5 GO:0031386 protein tag(GO:0031386)
1.3